Indole-3-carbinol triggers aryl hydrocarbon receptor-dependent estrogen receptor (ER)α protein degradation in breast cancer cells disrupting an ERαGATA3 transcriptional cross-regulatory loop

Molecular Biology of the Cell

Volumn 21, Issue 7, 2010, Pages 1166-1177

  Marconett, Crystal N ^a   Sundar, Shyam N ^a   Poindexter, Kevin M ^a   Stueve, Theresa R ^a   Bjeldanes, Leonard F ^b   Firestone, Gary L ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3 INDOLEMETHANOL; ANTINEOPLASTIC AGENT; AROMATIC HYDROCARBON RECEPTOR; CARBON 13; ESTROGEN RECEPTOR ALPHA; TRANSCRIPTION FACTOR GATA 3;

3' UNTRANSLATED REGION; ARTICLE; BRASSICA; BREAST CANCER; CANCER CELL; CELL DISRUPTION; CHROMATIN IMMUNOPRECIPITATION; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; IMMUNOPRECIPITATION; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN INTERACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UBIQUITINATION; VEGETABLE; WESTERN BLOTTING;

BLOTTING, WESTERN; BRASSICA; BREAST NEOPLASMS; CELL LINE, TUMOR; ESTROGEN RECEPTOR ALPHA; GATA3 TRANSCRIPTION FACTOR; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; IMMUNOPRECIPITATION; INDOLES; MODELS, BIOLOGICAL; PROMOTER REGIONS, GENETIC; RECEPTORS, ARYL HYDROCARBON; RNA, SMALL INTERFERING; UBIQUITIN;

BRASSICA;

EID: 77950667476     PISSN: 10591524     EISSN: None     Source Type: Journal    
DOI: 10.1091/mbc.E09-08-0689     Document Type: Article

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