Resveratrol inhibits phorbol ester-induced cyclooxygenase-2 expression in mouse skin: MAPKs and AP-1 as potential molecular targets

BioFactors

Volumn 21, Issue 1-4, 2004, Pages 33-39

  Kundu, Joydeb Kumar ^a   Chun, Kyung Soo ^a   Kim, Sue O ^a   Surh, Young Joon ^a  

^a Seoul National University   (South Korea)

Author keywords

Activator protein 1; Chemoprevention; Cyclooxygenase 2 (COX 2); Mitogen activated protein kinase (MAPK); Mouse skin carcinogenesis; Resveratrol

Indexed keywords

CYCLOOXYGENASE 2; MITOGEN ACTIVATED PROTEIN KINASE; PHORBOL 13 ACETATE 12 MYRISTATE; RESVERATROL; TRANSCRIPTION FACTOR AP 1; ANTINEOPLASTIC AGENT; MITOGEN ACTIVATED PROTEIN KINASE P38; PROSTAGLANDIN SYNTHASE; STILBENE DERIVATIVE;

ANIMAL TISSUE; CONFERENCE PAPER; CONTROLLED STUDY; DNA BINDING; DOSE RESPONSE; DRUG EFFECT; ENZYME MECHANISM; FEMALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN TARGETING; REGULATORY MECHANISM; SKIN CARCINOGENESIS; ANIMAL; ARTICLE; DRUG ANTAGONISM; ENZYMOLOGY; GENE EXPRESSION REGULATION; GENETICS; INSTITUTE FOR CANCER RESEARCH MOUSE; METABOLISM; SKIN;

VITACEAE;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; CYCLOOXYGENASE 2; FEMALE; GENE EXPRESSION REGULATION, ENZYMOLOGIC; MICE; MICE, INBRED ICR; MITOGEN-ACTIVATED PROTEIN KINASES; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; SKIN; STILBENES; TETRADECANOYLPHORBOL ACETATE; TRANSCRIPTION FACTOR AP-1;

EID: 16444382588     PISSN: 09516433     EISSN: None     Source Type: Journal    
DOI: 10.1002/biof.552210108     Document Type: Conference Paper

References (27)

1. M. Jang, L. Cai, G.O. Udeani, K.V. Slowing, C.F. Thomas, C.W. Beecher, H.H. Fong, N.R. Farnsworth, A.D. Kinghorn, R.G. Mehta, R.C. Moon and J.M. Pezzuto, Cancer chemopreventive activity of resveratrol, a natural product derived from grapes, Science 275 (1997), 218-220.
2. P.M. Kris-Etherton, K.D. Hecker, A. Bonanome, S.M. Coval, A.E. Binkoski, K.F. Hilpert, A.E. Griel and T.D. Etherton, Bioactive compounds in foods: their role in the prevention of cardiovascular disease and cancer, Am. J. Med. 113 (2002), 71S-88S.
3. H.J. Kim, E.J. Chang, S.J. Bae, S.M. Shim, H.D. Park, C.H. Rhee, J.H. Park and S.W. Choi, Cytotoxic and antimutagenic stilbenes from seeds of Paeonia lactiflora, Arch. Pharm. Res. 25 (2002), 293-299.
4. Z. Dong, Molecular mechanism of the chemopreventive effect of resveratrol, Mutat Res. 523-524 (2003), 145-150.
5. Y. Cao and S.M. Prescott, Many actions of cyclooxygenase-2 in cellular dynamics and in cancer, J. Cell Physiol. 190 (2002), 279-286.
6. S. Mohan and J.B. Epstein, Carcinogenesis and cyclooxygenase: the potential role of COX-2 inhibition in upper aerodigestive tract cancer, Oral Oncol. 39 (2003), 537-546.
7. K. Muller-Decker, G. Neufang, I. Berger, M. Neumann, F. Marks and G. Furstenberger, Transgenic cyclooxygenase-2 overexpression sensitizes mouse skin for carcinogenesis, Proc. Natl. Acad. Sci. USA 99 (2002), 12483-12488.
8. H.F. Tiano, C.D. Loftin, J. Akunda, C.A. Lee, J. Spalding, A. Sessoms, D.B. Dunson, E.G. Rogan, S.G. Morham, R.C. Smart and R. Langenbach, Deficiency of either cyclooxygenase (COX)-1 or COX-2 alters epidermal differentiation and reduces mouse skin tumorigenesis, Cancer Res. 62 (2002), 3395-3401.
9. Y.-J. Surh, Anti-tumor promoting potential of selected spice ingredients with antioxidative and anti-inflammatory activities: a short review, Food Chem. Toxicol. 40 (2002), 1091-1097.
10. Y.-J. Surh, K.-S. Chun, H.H. Cha, S.S. Han, Y.S. Keum, K.K. Park and S.S. Lee, Molecular mechanisms underlying chemopreventive activities of anti-inflammatory phytochemicals: down-regulation of COX-2 and iNOS through suppression of NF-kappa B activation, Mutat. Res. 480-481 (2001), 243-268.
11. K. Subbaramaiah, W.J. Chung, P. Michaluart, N. Telang, T. Tanabe, H. Inoue, M. Jang, J.M. Pezzuto and A.J. Dannenberg, Resveratrol inhibits cyclooxygenase-2 transcription and activity in phorbol ester-treated human mammary epithelial cells, J. Biol. Chem. 273 (1998), 21875-21882.
12. K. Subbaramaiah, P. Michaluart, W.J. Chung, T. Tanabe, N. Telang and A.J. Dannenberg, Resveratrol inhibits cyclooxygenase-2 transcription in human mammary epithelial cells, Ann. N. Y. Acad. Sci. 889 (1999), 214-223.
13. S. Banerjee, C. Bueso-Ramos and B.B. Aggarwal, Suppression of 7,12-dimethylbenz(a)anthracene-induced mammary carcinogenesis in rats by resveratrol: role of nuclear factor-kappaB, cyclooxygenase 2, and matrix metalloprotease 9, Cancer Res. 62 (2002), 4945-4954.
14. J.K. Kundu, H.K. Na, K.-S. Chun, Y.K. Kim, S.J. Lee, S.S. Lee, O.S. Lee, Y.C. Sim and Y.-J. Surh, Inhibition of phorbol ester-induced COX-2 expression by epigallocatechin gallate in mouse skin and cultured human mammary epithelial cells, J. Nutr. 133 (2003), 3805S-3810S.
15. S.S. Han, Y.-S. Keum, H.J. Seo, K.-S. Chun, S.S. Lee and Y.-J. Surh, Capsaicin suppresses phorbol ester-induced activation of NF-κB/Rel and AP-1 transcription factors in mouse epidermis, Cancer Lett. 164 (2001), 119-126.
16. Y.-J. Surh, Cancer chemoprevention with dietary phytochemicals, Nature Rev Cancer 3 (2003), 768-780.
17. K. Subbaramaiah and A.J. Dannenberg, Cyclooxygenase 2: a molecular target for cancer prevention and treatment, Trends Pharmacol. Sci. 24 (2003), 96-102.
18. Y.-J. Surh, H.-K. Na, J.-Y. Lee and Y.-S. Keum, Molecular mechanisms underlying anti-tumor promoting activities of heat-processed Panax ginseng C.A. Meyer, J. Korean Med. Sci. 16 (2001), S38-S41.
19. 2 in anti-promotive process, J. Cell Physiol. 193 (2002), 93-102.
20. K.-S. Chun, Y.-S. Keum, S.S. Han, Y.S. Song, S.H. Kim and Y.-J. Surh, Curcumin inhibits phorbol ester-induced expression of cyclooxygenase-2 in mouse skin through suppression of extracellular signal-regulated kinase activity and NF-κB activation, Carcinogenesis 24 (2003), 1515-1524.
21. W. Xie, B.S. Fletcher, R.D. Andersen and H.R. Herschman, v-src induction of the TIS10/PGS2 prostaglandin synthase gene is mediated by an ATF/CRE transcription response element, Mol. Cell Biol. 14 (1994), 6531-6539.
22. D.J. Wadleigh and H.R. Herschman, Transcriptional regulation of the cyclooxygenase-2 gene by diverse ligands in murine osteoblasts, Biochem. Biophys. Res. Commun. 264 (1999), 865-870.
23. Y. Kim and S.M. Fischer, Transcriptional regulation of cyclooxygenase-2 in mouse skin carcinoma cells. Regulatory role of CCAAT/enhancer-binding proteins in the differential expression of cyclooxygenase-2 in normal and neoplastic tissues, J. Biol. Chem. 273 (1998), 27686-27694.
24. K. Cieslik, Y. Zhu and K.K. Wu, Salicylate suppresses macrophage nitric-oxide synthase-2 and cyclo-oxygenase-2 expression by inhibiting CCAAT/enhancer-binding protein-beta binding via a common signaling pathway, J. Biol. Chem. 277 (2002), 49304-49310.
25. K.-S. Chun, Y.-S. Song, S.-H. Kim and Y.-J. Surh, Celecoxib inhibits phorbol ester-induced COX-2 expression, AP-1 activation in mouse skin, Carcinogenesis 25 (2004), 713-722.
26. R. Yu, V. Hebbar, D.W. Kim, S. Mandlekar, J.M. Pezzuto and A.N. Kong, Resveratrol inhibits phorbol ester and UV-induced activator protein 1 activation by interfering with mitogen-activated protein kinase pathways, Mol. Pharmacol. 60 (2001), 217-224.
27. S.K. Manna, A. Mukhopadhyay and B.B. Aggarwal, Resveratrol suppresses TNF-induced activation of nuclear transcription factors NF-kappa B, activator protein-1, and apoptosis: potential role of reactive oxygen intermediates and lipid peroxidation, J. Immunol. 164 (2000), 6509-6519.