Genistein induces cell apoptosis in MDA-MB-231 breast cancer cells via the mitogen-activated protein kinase pathway

Toxicology in Vitro

Volumn 22, Issue 7, 2008, Pages 1749-1753

  Li, Zhong ^a   Li, Jing ^a   Mo, Baoqing ^a   Hu, Chunyan ^a   Liu, Huaqing ^a   Qi, Hong ^a   Wang, Xinru ^a   Xu, Jida ^a  

^a NANJING MEDICAL UNIVERSITY   (China)

Author keywords

Apoptosis; Breast cancer cells; Genistein; MAPK pathway

Indexed keywords

CASPASE 3; DNA; GENISTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 7; MITOGEN ACTIVATED PROTEIN KINASE KINASE 5; PROTEIN BAX; PROTEIN BCL 2; SYNAPTOTAGMIN I;

APOPTOSIS; ARTICLE; BINDING SITE; BREAST CANCER; CANCER CELL; CELL GROWTH; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA BINDING; DOWN REGULATION; DRUG INHIBITION; ENZYME ACTIVITY; HUMAN; HUMAN CELL; PROTEIN EXPRESSION; REGULATORY MECHANISM; UPREGULATION;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; BREAST NEOPLASMS; CELL LINE, TUMOR; CELL PROLIFERATION; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; GENISTEIN; HUMANS; MAP KINASE KINASE 5; MITOGEN-ACTIVATED PROTEIN KINASE 7; MITOGEN-ACTIVATED PROTEIN KINASES; NF-KAPPA B; SOYBEANS;

GLYCINE MAX;

EID: 51749113325     PISSN: 08872333     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tiv.2008.08.001     Document Type: Article

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