Indole-3-carbinol inhibits the expression of cyclin-dependent kinase-6 and induces a G1 cell cycle arrest of human breast cancer cells independent of estrogen receptor signaling

Journal of Biological Chemistry

Volumn 273, Issue 7, 1998, Pages 3838-3847

  Cover, Carolyn M ^a   Hsieh, S Jean ^a   Tran, Susan H ^a   Hallden, Gunnell ^a   Kim, Gloria S ^a   Bjeldanes, Leonard F ^b   Firestone, Gary L ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3 INDOLEMETHANOL; CYCLIN DEPENDENT KINASE; CYCLIN DEPENDENT KINASE INHIBITOR; ESTROGEN RECEPTOR; RETINOBLASTOMA PROTEIN; TAMOXIFEN;

ARTICLE; BREAST CANCER; CANCER INHIBITION; CELL CYCLE G1 PHASE; CELL STRAIN MCF 7; CONTROLLED STUDY; HORMONE RECEPTOR INTERACTION; HUMAN; HUMAN CELL; PRIORITY JOURNAL;

BREAST NEOPLASMS; CELL CYCLE; CELL DIVISION; CYCLIN-DEPENDENT KINASE 6; CYCLIN-DEPENDENT KINASES; DNA REPLICATION; ESTROGEN ANTAGONISTS; FLOW CYTOMETRY; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; INDOLES; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; RECEPTORS, ESTROGEN; RETINOBLASTOMA PROTEIN; RNA, MESSENGER; SIGNAL TRANSDUCTION; TAMOXIFEN; TUMOR CELLS, CULTURED;

BRASSICA; BRASSICA OLERACEA VAR. BOTRYTIS; BRASSICA OLERACEA VAR. CAPITATA; BRASSICA OLERACEA VAR. GEMMIFERA;

EID: 0032512820     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.273.7.3838     Document Type: Article

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