Indole-3-carbinol inhibits Sp1-induced matrix metalloproteinase-2 expression to attenuate migration and invasion of breast cancer cells

Journal of Agricultural and Food Chemistry

Volumn 57, Issue 1, 2009, Pages 76-82

  Hung, Wen Chun ^a   Chang, Hui Chiu ^a,b  

^a NATIONAL SUN YAT SEN UNIVERSITY   (Taiwan)

^b KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

Author keywords

Extracellular signal regulated kinase; Indole 3 carbinol; Matrix metalloproteinase; Sp1

Indexed keywords

3 INDOLEMETHANOL; GELATINASE A; INDOLE DERIVATIVE; INDOLE-3-CARBINOL; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR SP1;

ARTICLE; BINDING SITE; BRASSICACEAE; BREAST TUMOR; CANCER INVASION; CELL MOTION; CHEMISTRY; DRUG ANTAGONISM; DRUG EFFECT; GENE EXPRESSION; GENETICS; HUMAN; METABOLISM; PROMOTER REGION; SIGNAL TRANSDUCTION; TUMOR CELL LINE;

BINDING SITES; BRASSICACEAE; BREAST NEOPLASMS; CELL LINE, TUMOR; CELL MOVEMENT; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GENE EXPRESSION; HUMANS; INDOLES; MATRIX METALLOPROTEINASE 2; NEOPLASM INVASIVENESS; PROMOTER REGIONS, GENETIC; RNA, MESSENGER; SIGNAL TRANSDUCTION; SP1 TRANSCRIPTION FACTOR;

EID: 59849109215     PISSN: 00218561     EISSN: None     Source Type: Journal    
DOI: 10.1021/jf802881d     Document Type: Article

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