-
1
-
-
39749106670
-
Identifying breast cancer druggable oncogenic alterations: Lessons learned and future targeted options
-
Ocaña, A., Pandiella, A., Identifying breast cancer druggable oncogenic alterations: lessons learned and future targeted options. Clin. Cancer Res. 2008, 14, 961-970.
-
(2008)
Clin. Cancer Res
, vol.14
, pp. 961-970
-
-
Ocaña, A.1
Pandiella, A.2
-
2
-
-
0027285606
-
The lifetime risk of developing breast cancer
-
Feuer, E. J., Wun, L. M., Boring, C. C., Flanders, W. D. et al., The lifetime risk of developing breast cancer. J. Natl. Cancer Inst. 1993, 85, 892-897.
-
(1993)
J. Natl. Cancer Inst
, vol.85
, pp. 892-897
-
-
Feuer, E.J.1
Wun, L.M.2
Boring, C.C.3
Flanders, W.D.4
-
3
-
-
43149120688
-
Development of new targeted therapies for breast cancer
-
Doyle, D. M., Miller, K. D., Development of new targeted therapies for breast cancer. Breast Cancer 2008, 15, 49-56.
-
(2008)
Breast Cancer
, vol.15
, pp. 49-56
-
-
Doyle, D.M.1
Miller, K.D.2
-
4
-
-
0028345763
-
Reactive oxygen species in tumorigenesis
-
Feig, D. I., Reid, T. M., Loeb, L. A., Reactive oxygen species in tumorigenesis. Cancer Res. 1994, 54, 1890s-1894s.
-
(1994)
Cancer Res
, vol.54
-
-
Feig, D.I.1
Reid, T.M.2
Loeb, L.A.3
-
5
-
-
33748165596
-
Reactive oxygen species in cancer cells: Live by the sword, die by the sword
-
Schumacker, P. T., Reactive oxygen species in cancer cells: live by the sword, die by the sword. Cancer Cell 2006, 10, 175-176.
-
(2006)
Cancer Cell
, vol.10
, pp. 175-176
-
-
Schumacker, P.T.1
-
6
-
-
33750913133
-
Redox regulation of human thioredoxin network
-
Kondo, N., Nakamura, H., Masutani, H., Yodoi, J., Redox regulation of human thioredoxin network. Antioxid. Redox. Signal. 2006, 8, 1881-1890.
-
(2006)
Antioxid. Redox. Signal
, vol.8
, pp. 1881-1890
-
-
Kondo, N.1
Nakamura, H.2
Masutani, H.3
Yodoi, J.4
-
7
-
-
33751183316
-
Ginsenoside-Rh2-induced mitochondrial depolarization and apoptosis are associated with reactive oxygen species- and Ca21-mediated c-Jun NH2-terminal kinase 1 activation in HeLa cells
-
Ham, Y. M., Lim, J. H., Na, H. K., Choi, J. S. et al., Ginsenoside-Rh2-induced mitochondrial depolarization and apoptosis are associated with reactive oxygen species- and Ca21-mediated c-Jun NH2-terminal kinase 1 activation in HeLa cells. J. Pharmacol. Exp. Ther. 2006, 319, 1276-1285.
-
(2006)
J. Pharmacol. Exp. Ther
, vol.319
, pp. 1276-1285
-
-
Ham, Y.M.1
Lim, J.H.2
Na, H.K.3
Choi, J.S.4
-
8
-
-
33751180574
-
Reactive oxygen species mediate caspase activation and apoptosis induced by lipoic acid in human lung epithelial cancer cells through Bcl-2 down-regulation
-
Moungjaroen, J., Nimmannit, U., Callery, P. S., Wang, L. et al., Reactive oxygen species mediate caspase activation and apoptosis induced by lipoic acid in human lung epithelial cancer cells through Bcl-2 down-regulation. J. Pharmacol. Exp. Ther. 2006, 319, 1062-1069.
-
(2006)
J. Pharmacol. Exp. Ther
, vol.319
, pp. 1062-1069
-
-
Moungjaroen, J.1
Nimmannit, U.2
Callery, P.S.3
Wang, L.4
-
9
-
-
25644457401
-
Genipininduced apoptosis in hepatoma cells is mediated by reactive oxygenspecies/c-Jun NH2-terminal kinase-dependent activation of mitochondrial pathway
-
Kim, B. C., Kim, H. G., Lee, S. A., Lim, S. et al., Genipininduced apoptosis in hepatoma cells is mediated by reactive oxygenspecies/c-Jun NH2-terminal kinase-dependent activation of mitochondrial pathway. Biochem. Pharmacol. 2005, 70, 1398-1407.
-
(2005)
Biochem. Pharmacol
, vol.70
, pp. 1398-1407
-
-
Kim, B.C.1
Kim, H.G.2
Lee, S.A.3
Lim, S.4
-
10
-
-
1542405935
-
Reactive oxygen species (ROS), troublemakers between nuclear factor-kappaB (NF-kappaB) and c-Jun NH(2)-terminal kinase (JNK)
-
Zhang, Y., Chen, F., Reactive oxygen species (ROS), troublemakers between nuclear factor-kappaB (NF-kappaB) and c-Jun NH(2)-terminal kinase (JNK). Cancer Res. 2004, 64, 1902-1905.
-
(2004)
Cancer Res
, vol.64
, pp. 1902-1905
-
-
Zhang, Y.1
Chen, F.2
-
11
-
-
34547641948
-
Isoobtusilactone A induces cell cycle arrest and apoptosis through reactive oxygen species/apoptosis signal-regulating kinase 1 signaling pathway in human breast cancer cells
-
Kuo, P. L., Chen, C. Y., Hsu, Y. L., Isoobtusilactone A induces cell cycle arrest and apoptosis through reactive oxygen species/apoptosis signal-regulating kinase 1 signaling pathway in human breast cancer cells. Cancer Res. 2007, 67, 7406-7420.
-
(2007)
Cancer Res
, vol.67
, pp. 7406-7420
-
-
Kuo, P.L.1
Chen, C.Y.2
Hsu, Y.L.3
-
12
-
-
33947379619
-
Cancer preventive properties of ginger: A brief review
-
Shukla, Y., Singh, M., Cancer preventive properties of ginger: a brief review. Food Chem. Toxicol. 2007, 45, 683-690.
-
(2007)
Food Chem. Toxicol
, vol.45
, pp. 683-690
-
-
Shukla, Y.1
Singh, M.2
-
13
-
-
4143081630
-
Zerumbone, a tropical ginger sesquiterpene, activates phase II drug metabolizing enzymes
-
Nakamura, Y., Yoshida, C., Murakami, A., Ohigashi, H. et al., Zerumbone, a tropical ginger sesquiterpene, activates phase II drug metabolizing enzymes. FEBS Lett. 2004, 572, 245-250.
-
(2004)
FEBS Lett
, vol.572
, pp. 245-250
-
-
Nakamura, Y.1
Yoshida, C.2
Murakami, A.3
Ohigashi, H.4
-
14
-
-
23844534499
-
Isolation of a natural antioxidant, dehydrozingerone from Zingiber officinale and synthesis of its analogues for recognition of effective antioxidant and antityrosinase agents
-
Kuo, P. C., Damu, A. G., Cherng, C. Y., Jeng, J. F. et al., Isolation of a natural antioxidant, dehydrozingerone from Zingiber officinale and synthesis of its analogues for recognition of effective antioxidant and antityrosinase agents. Arch. Pharm. Res. 2005, 28, 518-528.
-
(2005)
Arch. Pharm. Res
, vol.28
, pp. 518-528
-
-
Kuo, P.C.1
Damu, A.G.2
Cherng, C.Y.3
Jeng, J.F.4
-
15
-
-
50149122595
-
Mosquito larvicidal activity of isolated compounds from the rhizome of Zingiber officinale
-
Rahuman, A. A., Gopalakrishnan, G., Venkatesan, P., Geetha, K., Bagavan, A., Mosquito larvicidal activity of isolated compounds from the rhizome of Zingiber officinale. Phytother. Res. 2008, 22, 1035-1039.
-
(2008)
Phytother. Res
, vol.22
, pp. 1035-1039
-
-
Rahuman, A.A.1
Gopalakrishnan, G.2
Venkatesan, P.3
Geetha, K.4
Bagavan, A.5
-
16
-
-
34247842982
-
6-Shogaol (alkanone from ginger) induces apoptotic cell death of human hepatoma p53 mutant Mahlavu subline via an oxidative stress-mediated caspase-dependent mechanism
-
Chen, C. Y., Liu, T. Z., Liu, Y. W., Tseng, W. C. et al., 6-Shogaol (alkanone from ginger) induces apoptotic cell death of human hepatoma p53 mutant Mahlavu subline via an oxidative stress-mediated caspase-dependent mechanism. J. Agric. Food Chem. 2007, 55, 948-954.
-
(2007)
J. Agric. Food Chem
, vol.55
, pp. 948-954
-
-
Chen, C.Y.1
Liu, T.Z.2
Liu, Y.W.3
Tseng, W.C.4
-
17
-
-
38049068003
-
In vitro and in vivo modulation of testosterone mediated alterations in apoptosis related proteins by [6]-gingerol
-
Shukla, Y., Prasad, S., Tripathi, C., Singh, M. et al., In vitro and in vivo modulation of testosterone mediated alterations in apoptosis related proteins by [6]-gingerol. Mol. Nutr. Food Res. 2007, 51, 1492-1502.
-
(2007)
Mol. Nutr. Food Res
, vol.51
, pp. 1492-1502
-
-
Shukla, Y.1
Prasad, S.2
Tripathi, C.3
Singh, M.4
-
18
-
-
0032431687
-
Induction of apoptosis in HL-60 cells by pungent vanilloids, [6]-gingerol and [6]-paradol
-
Lee, E., Surh, Y. J., Induction of apoptosis in HL-60 cells by pungent vanilloids, [6]-gingerol and [6]-paradol. Cancer Lett. 1998, 134, 163-168.
-
(1998)
Cancer Lett
, vol.134
, pp. 163-168
-
-
Lee, E.1
Surh, Y.J.2
-
19
-
-
23644434954
-
5-HT3 receptor blocking activity of arylalkanes isolated from the rhizome of Zingiber officinale
-
Abdel-Aziz, H., Nahrstedt, A., Petereit, F., Windeck, T. et al., 5-HT3 receptor blocking activity of arylalkanes isolated from the rhizome of Zingiber officinale. Planta Med. 2005, 71, 609-616.
-
(2005)
Planta Med
, vol.71
, pp. 609-616
-
-
Abdel-Aziz, H.1
Nahrstedt, A.2
Petereit, F.3
Windeck, T.4
-
20
-
-
0019949095
-
Inhibitors of prostaglandin biosynthesis from ginger
-
Tokyo
-
Kiuchi, F., Shibuya, M., Sankawa, U., Inhibitors of prostaglandin biosynthesis from ginger. Chem. Pharm. Bull. (Tokyo) 1982, 30, 754-757.
-
(1982)
Chem. Pharm. Bull
, vol.30
, pp. 754-757
-
-
Kiuchi, F.1
Shibuya, M.2
Sankawa, U.3
-
21
-
-
2142753013
-
Diarylheptanoids from the rhizomes of Zingiber officinale
-
Ma, J., Jin, X., Yang, L., Liu, Z. L., Diarylheptanoids from the rhizomes of Zingiber officinale. Phytochemistry 2004, 65, 1137-1143.
-
(2004)
Phytochemistry
, vol.65
, pp. 1137-1143
-
-
Ma, J.1
Jin, X.2
Yang, L.3
Liu, Z.L.4
-
22
-
-
0016318441
-
Cellular tumorigenicity in nude mice: Correlation with cell growth in semi-solid medium
-
Freedman, V. H., Shin, S. I., Cellular tumorigenicity in nude mice: correlation with cell growth in semi-solid medium. Cell 1974, 3, 355-359.
-
(1974)
Cell
, vol.3
, pp. 355-359
-
-
Freedman, V.H.1
Shin, S.I.2
-
23
-
-
33644904306
-
Thioredoxin-ASK1 complex levels regulate ROS-mediated p38 MAPK pathway activity in livers of aged and long-lived Snell dwarf mice
-
Hsieh, C. C., Papaconstantinou, J., Thioredoxin-ASK1 complex levels regulate ROS-mediated p38 MAPK pathway activity in livers of aged and long-lived Snell dwarf mice. FASEB J. 2006, 20, 259-268.
-
(2006)
FASEB J
, vol.20
, pp. 259-268
-
-
Hsieh, C.C.1
Papaconstantinou, J.2
-
24
-
-
0030665150
-
The role of Cdc2 feedback loop control in the DNA damage checkpoint in mammalian cells
-
Poon, R. Y., Chau, M. S., Yamashita, K., Hunter, T., The role of Cdc2 feedback loop control in the DNA damage checkpoint in mammalian cells. Cancer Res. 1997, 57, 5168-5178.
-
(1997)
Cancer Res
, vol.57
, pp. 5168-5178
-
-
Poon, R.Y.1
Chau, M.S.2
Yamashita, K.3
Hunter, T.4
-
25
-
-
13244256828
-
Regulation of Cdc25C activity during the meiotic G2/M transition
-
Perdiguero, E., Nebreda, A. R., Regulation of Cdc25C activity during the meiotic G2/M transition. Cell Cycle 2004, 3, 733-737.
-
(2004)
Cell Cycle
, vol.3
, pp. 733-737
-
-
Perdiguero, E.1
Nebreda, A.R.2
-
26
-
-
0034641918
-
The biochemistry of apoptosis
-
Hengartner, M. O., The biochemistry of apoptosis. Nature 2000, 407, 770-776.
-
(2000)
Nature
, vol.407
, pp. 770-776
-
-
Hengartner, M.O.1
-
27
-
-
33847328289
-
The Bcl-2 apoptotic switch in cancer development and therapy
-
Adams, J. M., Cory, S., The Bcl-2 apoptotic switch in cancer development and therapy. Oncogene 2007, 26, 1324-1337.
-
(2007)
Oncogene
, vol.26
, pp. 1324-1337
-
-
Adams, J.M.1
Cory, S.2
-
28
-
-
33847349283
-
Reactive oxygen species: A breath of life or death? Clin
-
Fruehauf, J. P., Jr. Meyskens, F. L., Reactive oxygen species: a breath of life or death? Clin. Cancer Res. 2007, 13, 789-794.
-
(2007)
Cancer Res
, vol.13
, pp. 789-794
-
-
Fruehauf, J.P.1
Meyskens Jr., F.L.2
-
29
-
-
33644559338
-
Xanthine oxidase-dependent regulation of hypoxia-inducible factor in cancer cells
-
Griguer, C. E., Oliva, C. R., Kelley, E. E., Giles, G. I. et al., Xanthine oxidase-dependent regulation of hypoxia-inducible factor in cancer cells. Cancer Res. 2006, 66, 2257-2263.
-
(2006)
Cancer Res
, vol.66
, pp. 2257-2263
-
-
Griguer, C.E.1
Oliva, C.R.2
Kelley, E.E.3
Giles, G.I.4
-
30
-
-
33744910333
-
C-Jun NH(2)-terminal kinase signaling axis regulates diallyl trisulfide-induced generation of reactive oxygen species and cell cycle arrest in human prostate cancer cells
-
Antosiewicz, J., Herman-Antosiewicz, A., Marynowski, S. W., Singh, S.V., c-Jun NH(2)-terminal kinase signaling axis regulates diallyl trisulfide-induced generation of reactive oxygen species and cell cycle arrest in human prostate cancer cells. Cancer Res. 2006, 66, 5379-5386.
-
(2006)
Cancer Res
, vol.66
, pp. 5379-5386
-
-
Antosiewicz, J.1
Herman-Antosiewicz, A.2
Marynowski, S.W.3
Singh, S.V.4
-
31
-
-
20444505248
-
Emodin induces apoptosis in human lung adenocarcinoma cells through a reactive oxygen species-dependent mitochondrial signaling pathway
-
Su, T. T., Chang, H. L., Shyue, S. K., Hsu, S. L., Emodin induces apoptosis in human lung adenocarcinoma cells through a reactive oxygen species-dependent mitochondrial signaling pathway. Biochem. Pharmacol. 2005, 70, 229-241.
-
(2005)
Biochem. Pharmacol
, vol.70
, pp. 229-241
-
-
Su, T.T.1
Chang, H.L.2
Shyue, S.K.3
Hsu, S.L.4
-
32
-
-
33744994567
-
Glutathione in cancer biology and therapy
-
Estrela, J. M., Ortega, A., Obrador, E., Glutathione in cancer biology and therapy. Crit. Rev. Clin. Lab. Sci. 2006, 43, 143-181.
-
(2006)
Crit. Rev. Clin. Lab. Sci
, vol.43
, pp. 143-181
-
-
Estrela, J.M.1
Ortega, A.2
Obrador, E.3
-
33
-
-
32444433202
-
Free radicals, metals and antioxidants in oxidative stressinduced cancer
-
Valko, M., Rhodes, C. J., Moncol, J., Izakovic, M., Mazur, M., Free radicals, metals and antioxidants in oxidative stressinduced cancer. Chem. Biol. Interact. 2006, 160, 1-40.
-
(2006)
Chem. Biol. Interact
, vol.160
, pp. 1-40
-
-
Valko, M.1
Rhodes, C.J.2
Moncol, J.3
Izakovic, M.4
Mazur, M.5
-
34
-
-
13944274587
-
Up-regulation of c-Jun-NH2-kinase pathway contributes to the induction of mitochondria-mediated apoptosis by alpha-tocopheryl succinate in human prostate cancer cells
-
Zu, K., Hawthorn, L., Ip, C., Up-regulation of c-Jun-NH2-kinase pathway contributes to the induction of mitochondria-mediated apoptosis by alpha-tocopheryl succinate in human prostate cancer cells. Mol. Cancer Ther. 2005, 4, 43-50.
-
(2005)
Mol. Cancer Ther
, vol.4
, pp. 43-50
-
-
Zu, K.1
Hawthorn, L.2
Ip, C.3
-
35
-
-
33846805634
-
Eupalmerin acetate, a novel anticancer agent from Caribbean gorgonian octocorals, induces apoptosis in malignant glioma cells via the c-Jun NH2-terminal kinase pathway
-
Iwamaru, A., Iwado, E., Kondo, S., Newman, R. A. et al., Eupalmerin acetate, a novel anticancer agent from Caribbean gorgonian octocorals, induces apoptosis in malignant glioma cells via the c-Jun NH2-terminal kinase pathway. Mol. Cancer Ther. 2007, 6, 184-192.
-
(2007)
Mol. Cancer Ther
, vol.6
, pp. 184-192
-
-
Iwamaru, A.1
Iwado, E.2
Kondo, S.3
Newman, R.A.4
-
36
-
-
2442501565
-
Ascorbic acid suppresses drug-induced apoptosis in human colon cancer cells by scavenging mitochondrial superoxide anions
-
Wenzel, U., Nickel, A., Kuntz, S., Daniel, H., Ascorbic acid suppresses drug-induced apoptosis in human colon cancer cells by scavenging mitochondrial superoxide anions. Carcinogenesis 2004, 25, 703-712.
-
(2004)
Carcinogenesis
, vol.25
, pp. 703-712
-
-
Wenzel, U.1
Nickel, A.2
Kuntz, S.3
Daniel, H.4
-
37
-
-
0037430452
-
Overexpression of mitogenactivated protein kinase phosphatases MKP1, MKP2 in human breast cancer
-
Wang, H. Y., Cheng, Z., Malbon, C. C., Overexpression of mitogenactivated protein kinase phosphatases MKP1, MKP2 in human breast cancer. Cancer Lett. 2003, 191, 229-237.
-
(2003)
Cancer Lett
, vol.191
, pp. 229-237
-
-
Wang, H.Y.1
Cheng, Z.2
Malbon, C.C.3
-
38
-
-
33745967219
-
Plumbagin (5-hydroxy-2-methyl-1,4-naphthoquinone) induces apoptosis and cell cycle arrest in A549 cells through p53 accumulation via c-Jun NH2-terminal kinasemediated phosphorylation at serine 15 in vitro and in vivo
-
Hsu, Y. L., Cho, C. Y., Kuo, P. L., Huang, Y. T., Lin, C. C., Plumbagin (5-hydroxy-2-methyl-1,4-naphthoquinone) induces apoptosis and cell cycle arrest in A549 cells through p53 accumulation via c-Jun NH2-terminal kinasemediated phosphorylation at serine 15 in vitro and in vivo. J. Pharmacol. Exp. Ther. 2006, 318, 484-494.
-
(2006)
J. Pharmacol. Exp. Ther
, vol.318
, pp. 484-494
-
-
Hsu, Y.L.1
Cho, C.Y.2
Kuo, P.L.3
Huang, Y.T.4
Lin, C.C.5
|