-
1
-
-
24644441655
-
The role of radiotherapy in cancer treatment: Estimating optimal utilization from a review of evidence-based clinical guidelines
-
DOI 10.1002/cncr.21324
-
Delaney, G., Jacob, S., Featherstone, C. & Barton, M. The role of radiotherapy in cancer treatment: estimating optimal utilization from a review of evidence-based clinical guidelines. Cancer 104, 1129-1137 (2005). (Pubitemid 41278947)
-
(2005)
Cancer
, vol.104
, Issue.6
, pp. 1129-1137
-
-
Delaney, G.1
Jacob, S.2
Featherstone, C.3
Barton, M.4
-
3
-
-
77951540327
-
Recent advances in radiotherapy
-
Bhide, S. A. & Nutting, C. M. Recent advances in radiotherapy. BMC Med. 8, 25 (2010).
-
(2010)
BMC Med.
, vol.8
, pp. 25
-
-
Bhide, S.A.1
Nutting, C.M.2
-
4
-
-
26444466467
-
Prognostic value of tumor oxygenation in 397 head and neck tumors after primary radiation therapy. An international multi-center study
-
DOI 10.1016/j.radonc.2005.06.038, PII S0167814005002823
-
Nordsmark, M. et al. Prognostic value of tumor oxygenation in 397 head and neck tumors after primary radiation therapy. An international multi-center study. Radiother. Oncol. 77, 18-24 (2005). (Pubitemid 41503384)
-
(2005)
Radiotherapy and Oncology
, vol.77
, Issue.1
, pp. 18-24
-
-
Nordsmark, M.1
Bentzen, S.M.2
Rudat, V.3
Brizel, D.4
Lartigau, E.5
Stadler, P.6
Becker, A.7
Adam, M.8
Molls, M.9
Dunst, J.10
Terris, D.J.11
Overgaard, J.12
-
5
-
-
21744437791
-
Repopulation of cancer cells during therapy: An important cause of treatment failure
-
DOI 10.1038/nrc1650
-
Kim, J. J. & Tannock, I. F. Repopulation of cancer cells during therapy: an important cause of treatment failure. Nature Rev. Cancer 5, 516-525 (2005). (Pubitemid 40942828)
-
(2005)
Nature Reviews Cancer
, vol.5
, Issue.7
, pp. 516-525
-
-
Kim, J.J.1
Tannock, I.F.2
-
6
-
-
0023894783
-
The hazard of accelerated tumor clonogen repopulation during radiotherapy
-
Withers, H. R., Taylor, J. M. & Maciejewski, B. The hazard of accelerated tumor clonogen repopulation during radiotherapy. Acta Oncol. 27, 131-146 (1988).
-
(1988)
Acta Oncol.
, vol.27
, pp. 131-146
-
-
Withers, H.R.1
Taylor, J.M.2
MacIejewski, B.3
-
7
-
-
0027379128
-
Intrinsic radiosensitivity and prediction of patient response to radiotherapy for carcinoma of the cervix
-
West, C. M., Davidson, S. E., Roberts, S. A. & Hunter, R. D. Intrinsic radiosensitivity and prediction of patient response to radiotherapy for carcinoma of the cervix. Br. J. Cancer 68, 819-823 (1993). (Pubitemid 23301293)
-
(1993)
British Journal of Cancer
, vol.68
, Issue.4
, pp. 819-823
-
-
West, C.M.L.1
Davidson, S.E.2
Roberts, S.A.3
Hunter, R.D.4
-
8
-
-
77952389941
-
Inhibition of Mac-1 (CD11b/CD18) enhances tumor response to radiation by reducing myeloid cell recruitment
-
Ahn, G. O. et al. Inhibition of Mac-1 (CD11b/CD18) enhances tumor response to radiation by reducing myeloid cell recruitment. Proc. Natl Acad. Sci. USA 107, 8363-8368 (2010).
-
(2010)
Proc. Natl Acad. Sci. USA
, vol.107
, pp. 8363-8368
-
-
Ahn, G.O.1
-
9
-
-
77949697909
-
Inhibition of vasculogenesis, but not angiogenesis, prevents the recurrence of glioblastoma after irradiation in mice
-
Kioi, M. et al. Inhibition of vasculogenesis, but not angiogenesis, prevents the recurrence of glioblastoma after irradiation in mice. J. Clin. Invest. 120, 694-705 (2010).
-
(2010)
J. Clin. Invest.
, vol.120
, pp. 694-705
-
-
Kioi, M.1
-
10
-
-
70350504453
-
The DNA-damage response in human biology and disease
-
Jackson, S. P. & Bartek, J. The DNA-damage response in human biology and disease. Nature 461, 1071-1078 (2009).
-
(2009)
Nature
, vol.461
, pp. 1071-1078
-
-
Jackson, S.P.1
Bartek, J.2
-
11
-
-
42049089502
-
DNA damage responses: Mechanisms and roles in human disease: 2007 G. H.-A. Clowes Memorial Award Lecture
-
Kastan, M. B. DNA damage responses: mechanisms and roles in human disease: 2007 G. H.-A. Clowes Memorial Award Lecture. Mol. Cancer Res. 6, 517-524 (2008).
-
(2008)
Mol. Cancer Res.
, vol.6
, pp. 517-524
-
-
Kastan, M.-B.1
-
12
-
-
35548978945
-
The impact of a negligent G2/M checkpoint on genomic instability and cancer induction
-
DOI 10.1038/nrc2248, PII NRC2248
-
Lobrich, M. & Jeggo, P. A. The impact of a negligent G2/M checkpoint on genomic instability and cancer induction. Nature Rev. Cancer 7, 861-869 (2007). (Pubitemid 350006255)
-
(2007)
Nature Reviews Cancer
, vol.7
, Issue.11
, pp. 861-869
-
-
Lobrich, M.1
Jeggo, P.A.2
-
13
-
-
77649175453
-
Genomic instability-an evolving hallmark of cancer
-
Negrini, S., Gorgoulis, V. G. & Halazonetis, T. D. Genomic instability-an evolving hallmark of cancer. Nature Rev. Mol. Cell Biol. 11, 220-228 (2010).
-
(2010)
Nature Rev. Mol. Cell Biol.
, vol.11
, pp. 220-228
-
-
Negrini, S.1
Gorgoulis, V.G.2
Halazonetis, T.-D.3
-
14
-
-
23844520213
-
ATM activation in normal human tissues and testicular cancer
-
Bartkova, J. et al. ATM activation in normal human tissues and testicular cancer. Cell Cycle 4, 838-845 (2005). (Pubitemid 41353838)
-
(2005)
Cell Cycle
, vol.4
, Issue.6
, pp. 838-845
-
-
Bartkova, J.1
Bakkenist, C.J.2
Rajpert-De Meyts, E.3
Skakkebaek, N.E.4
Sehested, M.5
Lukas, J.6
Kastan, M.B.7
Bartek, J.8
-
15
-
-
72049089840
-
Cellular radiosensitivity: How much better do we understand it?
-
Jeggo, P. & Lavin, M. F. Cellular radiosensitivity: how much better do we understand it? Int. J. Radiat. Biol. 85, 1061-1081 (2009).
-
(2009)
Int. J. Radiat. Biol.
, vol.85
, pp. 1061-1081
-
-
Jeggo, P.1
Lavin, M.-F.2
-
16
-
-
29244437908
-
The role of double-strand break repair - Insights from human genetics
-
DOI 10.1038/nrg1746
-
O'Driscoll, M. & Jeggo, P. A. The role of double-strand break repair - insights from human genetics. Nature Rev. Genet. 7, 45-54 (2006). (Pubitemid 41828947)
-
(2006)
Nature Reviews Genetics
, vol.7
, Issue.1
, pp. 45-54
-
-
O'Driscoll, M.1
Jeggo, P.A.2
-
17
-
-
34247599335
-
A unified view of base excision repair: Lesion-dependent protein complexes regulated by post-translational modification
-
DOI 10.1016/j.dnarep.2007.01.009, PII S1568786407000274
-
Almeida, K. H. & Sobol, R. W. A unified view of base excision repair: lesion-dependent protein complexes regulated by post-translational modification. DNA Repair (Amst). 6, 695-711 (2007). (Pubitemid 46670095)
-
(2007)
DNA Repair
, vol.6
, Issue.6
, pp. 695-711
-
-
Almeida, K.H.1
Sobol, R.W.2
-
18
-
-
48249095920
-
Single-strand break repair and genetic disease
-
Caldecott, K. W. Single-strand break repair and genetic disease. Nature Rev. Genet. 9, 619-631 (2008).
-
(2008)
Nature Rev. Genet.
, vol.9
, pp. 619-631
-
-
Caldecott, K.-W.1
-
19
-
-
0034876617
-
Securing genome stability by orchestrating DNA repair: Removal of radiation-induced clustered lesions in DNA
-
DOI 10.1002/bies.1104
-
Dianov, G. L., O'Neill, P. & Goodhead, D. T. Securing genome stability by orchestrating DNA repair: removal of radiation-induced clustered lesions in DNA. Bioessays 23, 745-749 (2001). (Pubitemid 32792519)
-
(2001)
BioEssays
, vol.23
, Issue.8
, pp. 745-749
-
-
Dianov, G.L.1
O'Neill, P.2
Goodhead, D.T.3
-
20
-
-
0034753408
-
Contribution of base lesions to radiation-induced clustered DNA damage: Implication for models of radiation response
-
Jenner, T. J., Fulford, J. & O'Neill, P. Contribution of base lesions to radiation-induced clustered DNA damage: implication for models of radiation response. Radiat. Res. 156, 590-593 (2001). (Pubitemid 33027533)
-
(2001)
Radiation Research
, vol.156
, Issue.5
, pp. 590-593
-
-
Jenner, T.J.1
Fulford, J.2
O'Neill, P.3
-
21
-
-
0141619287
-
Radiosensitization and DNA repair inhibition by the combined use of novel inhibitors of DNA-dependent protein kinase and poly(ADP-ribose) polymerase-1
-
Veuger, S. J., Curtin, N. J., Richardson, C. J., Smith, G. C. & Durkacz, B. W. Radiosensitization and DNA repair inhibition by the combined use of novel inhibitors of DNA-dependent protein kinase and poly(ADP-ribose) polymerase-1. Cancer Res. 63, 6008-6015 (2003). (Pubitemid 37187504)
-
(2003)
Cancer Research
, vol.63
, Issue.18
, pp. 6008-6015
-
-
Veuger, S.J.1
Curtin, N.J.2
Richardson, C.J.3
Smith, G.C.M.4
Durkacz, B.W.5
-
22
-
-
9744271049
-
Identification and characterization of a novel and specific inhibitor of the ataxia-telangiectasia mutated kinase ATM
-
DOI 10.1158/0008-5472.CAN-04-2727
-
Hickson, I. et al. Identification and characterization of a novel and specific inhibitor of the ataxia-telangiectasia mutated kinase ATM. Cancer Res. 64, 9152-9159 (2004). (Pubitemid 39665530)
-
(2004)
Cancer Research
, vol.64
, Issue.24
, pp. 9152-9159
-
-
Hickson, I.1
Zhao, Y.2
Richardson, C.J.3
Green, S.J.4
Martin, N.M.B.5
Orr, A.I.6
Reaper, P.M.7
Jackson, S.P.8
Curtin, N.J.9
Smith, G.C.M.10
-
23
-
-
54749148734
-
Transient inhibition of ATM kinase is sufficient to enhance cellular sensitivity to ionizing radiation
-
Rainey, M. D., Charlton, M. E., Stanton, R. V. & Kastan, M. B. Transient inhibition of ATM kinase is sufficient to enhance cellular sensitivity to ionizing radiation. Cancer Res. 68, 7466-7474 (2008).
-
(2008)
Cancer Res.
, vol.68
, pp. 7466-7474
-
-
Rainey, M.D.1
Charlton, M.E.2
Stanton, R.V.3
Kastan, M.B.4
-
24
-
-
77956487620
-
Poly(ADP-ribose) polymerase inhibition as a model for synthetic lethality in developing radiation oncology targets
-
Chalmers, A. J., Lakshman, M., Chan, N. & Bristow,-R. G. Poly(ADP-ribose) polymerase inhibition as a model for synthetic lethality in developing radiation oncology targets. Semin. Radiat. Oncol. 20, 274-281 (2010).
-
(2010)
Semin. Radiat. Oncol.
, vol.20
, pp. 274-281
-
-
Chalmers, A.J.1
Lakshman, M.2
Chan, N.3
Bristow, R.G.4
-
25
-
-
33645469913
-
Radiosensitization by the poly(ADP-ribose) polymerase inhibitor 4-amino-1,8-naphthalimide is specific of the S phase of the cell cycle and involves arrest of DNA synthesis
-
Noel, G. et al. Radiosensitization by the poly(ADP-ribose) polymerase inhibitor 4-amino-1,8-naphthalimide is specific of the S phase of the cell cycle and involves arrest of DNA synthesis. Mol. Cancer Ther. 5, 564-574 (2006).
-
(2006)
Mol. Cancer Ther.
, vol.5
, pp. 564-574
-
-
Noel, G.1
-
26
-
-
54049112348
-
Replication-dependent radiosensitization of human glioma cells by inhibition of poly(ADP-Ribose) polymerase: Mechanisms and therapeutic potential
-
Dungey, F. A., Loser, D. A. & Chalmers, A. J. Replication-dependent radiosensitization of human glioma cells by inhibition of poly(ADP-Ribose) polymerase: mechanisms and therapeutic potential. Int. J. Radiat. Oncol. Biol. Phys. 72, 1188-1197 (2008).
-
(2008)
Int. J. Radiat. Oncol. Biol. Phys.
, vol.72
, pp. 1188-1197
-
-
Dungey, F.A.1
Loser, D.A.2
Chalmers, A.-J.3
-
27
-
-
10744226451
-
Anticancer chemosensitization and radiosensitization by the novel poly(ADP-ribose) polymerase-1 inhibitor AG14361
-
Calabrese, C. R. et al. Anticancer chemosensitization and radiosensitization by the novel poly(ADP-ribose) polymerase-1 inhibitor AG14361. J. Natl. Cancer Inst. 96, 56-67 (2004).
-
(2004)
J. Natl. Cancer Inst.
, vol.96
, pp. 56-67
-
-
Calabrese, C.R.1
-
28
-
-
34249784216
-
Inhibition of poly(ADP-ribose) polymerase enhances cell death and improves tumor growth delay in irradiated lung cancer models
-
DOI 10.1158/1078-0432.CCR-06-2872
-
Albert, J. M. et al. Inhibition of poly(ADP-ribose) polymerase enhances cell death and improves tumor growth delay in irradiated lung cancer models. Clin. Cancer Res. 13, 3033-3042 (2007). (Pubitemid 46849580)
-
(2007)
Clinical Cancer Research
, vol.13
, Issue.10
, pp. 3033-3042
-
-
Albert, J.M.1
Cao, C.2
Kwang, W.K.3
Willey, C.D.4
Geng, L.5
Xiao, D.6
Wang, H.7
Sandler, A.8
Johnson, D.H.9
Colevas, A.D.10
Low, J.11
Rothenberg, M.L.12
Lu, B.13
-
29
-
-
77950867012
-
Novel therapeutics in combination with radiotherapy to improve cancer treatment: Rationale, mechanisms of action and clinical perspective
-
Verheij, M., Vens, C. & van Triest, B. Novel therapeutics in combination with radiotherapy to improve cancer treatment: rationale, mechanisms of action and clinical perspective. Drug Resist. Updat. 13, 29-43 (2010).
-
(2010)
Drug Resist. Updat.
, vol.13
, pp. 29-43
-
-
Verheij, M.1
Vens, C.2
Van Triest, B.3
-
30
-
-
66749155332
-
Identification and characterization of inhibitors of human apurinic/apyrimidinic endonuclease APE1
-
Simeonov, A. et al. Identification and characterization of inhibitors of human apurinic/apyrimidinic endonuclease APE1. PLoS One 4, e5740 (2009).
-
(2009)
PLoS One
, vol.4
-
-
Simeonov, A.1
-
31
-
-
77955095659
-
Human AP endonuclease 1 (APE1): From mechanistic insights to druggable target in cancer
-
Abbotts, R. & Madhusudan, S. Human AP endonuclease 1 (APE1): from mechanistic insights to druggable target in cancer. Cancer Treat Rev. 36, 425-435 (2010).
-
(2010)
Cancer Treat Rev.
, vol.36
, pp. 425-435
-
-
Abbotts, R.1
Madhusudan, S.2
-
32
-
-
77950842499
-
A small interfering RNA screen of genes involved in DNA repair identifies tumor-specific radiosensitization by POLQ knockdown
-
Higgins, G. S. et al. A small interfering RNA screen of genes involved in DNA repair identifies tumor-specific radiosensitization by POLQ knockdown. Cancer Res. 70, 2984-2993 (2010).
-
(2010)
Cancer Res.
, vol.70
, pp. 2984-2993
-
-
Higgins, G.S.1
-
33
-
-
79251525596
-
Overexpression of POLQ confers a poor prognosis in early breast cancer patients
-
Higgins, G. S. et al. Overexpression of POLQ confers a poor prognosis in early breast cancer patients. Oncotarget. 1, 175-184 (2010).
-
(2010)
Oncotarget.
, vol.1
, pp. 175-184
-
-
Higgins, G.S.1
-
34
-
-
77955820979
-
DNA polymerase theta up-regulation is associated with poor survival in breast cancer, perturbs DNA replication, and promotes genetic instability
-
Lemee, F. et al. DNA polymerase theta up-regulation is associated with poor survival in breast cancer, perturbs DNA replication, and promotes genetic instability. Proc. Natl Acad. Sci. USA 107, 13390-13395 (2010).
-
(2010)
Proc. Natl Acad. Sci. USA
, vol.107
, pp. 13390-13395
-
-
Lemee, F.1
-
35
-
-
66249149058
-
EGFRvIII and DNA double-strand break repair: A molecular mechanism for radioresistance in glioblastoma
-
Mukherjee, B. et al. EGFRvIII and DNA double-strand break repair: a molecular mechanism for radioresistance in glioblastoma. Cancer Res. 69, 4252-4259 (2009).
-
(2009)
Cancer Res.
, vol.69
, pp. 4252-4259
-
-
Mukherjee, B.1
-
36
-
-
39749166975
-
DNA repair pathways as targets for cancer therapy
-
DOI 10.1038/nrc2342, PII NRC2342
-
Helleday, T., Petermann, E., Lundin, C., Hodgson, B. & Sharma, R. A. DNA repair pathways as targets for cancer therapy. Nature Rev. Cancer 8, 193-204 (2008). (Pubitemid 351301852)
-
(2008)
Nature Reviews Cancer
, vol.8
, Issue.3
, pp. 193-204
-
-
Helleday, T.1
Petermann, E.2
Lundin, C.3
Hodgson, B.4
Sharma, R.A.5
-
37
-
-
25444497278
-
The concept of synthetic lethality in the context of anticancer therapy
-
DOI 10.1038/nrc1691, PII N1691
-
Kaelin, W. G. Jr. The concept of synthetic lethality in the context of anticancer therapy. Nature Rev. Cancer 5, 689-698 (2005). (Pubitemid 41486362)
-
(2005)
Nature Reviews Cancer
, vol.5
, Issue.9
, pp. 689-698
-
-
Kaelin Jr., W.G.1
-
38
-
-
17244375049
-
Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase
-
DOI 10.1038/nature03443
-
Bryant, H. E. et al. Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase. Nature 434, 913-917 (2005). (Pubitemid 40559005)
-
(2005)
Nature
, vol.434
, Issue.7035
, pp. 913-917
-
-
Bryant, H.E.1
Schultz, N.2
Thomas, H.D.3
Parker, K.M.4
Flower, D.5
Lopez, E.6
Kyle, S.7
Meuth, M.8
Curtin, N.J.9
Helleday, T.10
-
39
-
-
17244373777
-
Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy
-
DOI 10.1038/nature03445
-
Farmer, H. et al. Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy. Nature 434, 917-921 (2005). (Pubitemid 40559006)
-
(2005)
Nature
, vol.434
, Issue.7035
, pp. 917-921
-
-
Farmer, H.1
McCabe, H.2
Lord, C.J.3
Tutt, A.H.J.4
Johnson, D.A.5
Richardson, T.B.6
Santarosa, M.7
Dillon, K.J.8
Hickson, I.9
Knights, C.10
Martin, N.M.B.11
Jackson, S.P.12
Smith, G.C.M.13
Ashworth, A.14
-
40
-
-
34248184445
-
Fanconi anemia pathway-deficient tumor cells are hypersensitive to inhibition of ataxia telangiectasia mutated
-
DOI 10.1172/JCI31245
-
Kennedy, R. D. et al. Fanconi anemia pathway-deficient tumor cells are hypersensitive to inhibition of ataxia telangiectasia mutated. J. Clin. Invest. 117, 1440-1449 (2007). (Pubitemid 46718432)
-
(2007)
Journal of Clinical Investigation
, vol.117
, Issue.5
, pp. 1440-1449
-
-
Kennedy, R.D.1
Chen, C.C.2
Stuckert, P.3
Archila, E.M.4
De La Vega, M.A.5
Moreau, L.A.6
Shimamura, A.7
D'Andrea, A.D.8
-
41
-
-
76649091939
-
ATM deficiency sensitizes mantle cell lymphoma cells to poly(ADP-ribose) polymerase-1 inhibitors
-
Williamson, C. T. et al. ATM deficiency sensitizes mantle cell lymphoma cells to poly(ADP-ribose) polymerase-1 inhibitors. Mol. Cancer Ther. 9, 347-357 (2010).
-
(2010)
Mol. Cancer Ther.
, vol.9
, pp. 347-357
-
-
Williamson, C.T.1
-
42
-
-
33748065304
-
Deficiency in the repair of DNA damage by homologous recombination and sensitivity to poly(ADP-ribose) polymerase inhibition
-
DOI 10.1158/0008-5472.CAN-06-0140
-
McCabe, N. et al. Deficiency in the repair of DNA damage by homologous recombination and sensitivity to poly(ADP-ribose) polymerase inhibition. Cancer Res. 66, 8109-8115 (2006). (Pubitemid 44299177)
-
(2006)
Cancer Research
, vol.66
, Issue.16
, pp. 8109-8115
-
-
McCabe, N.1
Turner, N.C.2
Lord, C.J.3
Kluzek, K.4
Bialkowska, A.5
Swift, S.6
Giavara, S.7
O'Connor, M.J.8
Tutt, A.N.9
Zdzienicka, M.Z.10
Smith, G.C.M.11
Ashworth, A.12
-
43
-
-
77956490653
-
Targeting base excision repair as a sensitization strategy in radiotherapy
-
Vens, C. & Begg, A. C. Targeting base excision repair as a sensitization strategy in radiotherapy. Semin. Radiat. Oncol. 20, 241-249 (2010).
-
(2010)
Semin. Radiat. Oncol.
, vol.20
, pp. 241-249
-
-
Vens, C.1
Begg, A.-C.2
-
44
-
-
78449302142
-
Targeted radiosensitization of cells expressing truncated DNA Polymerase β
-
Neijenhuis, S., Verwijs-Janssen, M., van den Broek, L. J., Begg, A. C. & Vens, C. Targeted radiosensitization of cells expressing truncated DNA Polymerase β. Cancer Res. 70, 8706-8714 (2010).
-
(2010)
Cancer Res.
, vol.70
, pp. 8706-8714
-
-
Neijenhuis, S.1
Verwijs-Janssen, M.2
Van Den Broek, L.J.3
Begg, A.C.4
Vens, C.5
-
45
-
-
39749114978
-
Hypoxia and metabolism: Hypoxia, DNA repair and genetic instability
-
DOI 10.1038/nrc2344, PII NRC2344
-
Bristow, R. G. & Hill, R. P. Hypoxia and metabolism. Hypoxia, DNA repair and genetic instability. Nature Rev. Cancer 8, 180-192 (2008). (Pubitemid 351301853)
-
(2008)
Nature Reviews Cancer
, vol.8
, Issue.3
, pp. 180-192
-
-
Bristow, R.G.1
Hill, R.P.2
-
46
-
-
39049163047
-
Chronic hypoxia decreases synthesis of homologous recombination proteins to offset chemoresistance and radioresistance
-
DOI 10.1158/0008-5472.CAN-07-5472
-
Chan, N. et al. Chronic hypoxia decreases synthesis of homologous recombination proteins to offset chemoresistance and radioresistance. Cancer Res. 68, 605-614 (2008). (Pubitemid 351380090)
-
(2008)
Cancer Research
, vol.68
, Issue.2
, pp. 605-614
-
-
Chan, N.1
Koritzinsky, M.2
Zhao, H.3
Bindra, R.4
Glazer, P.M.5
Powell, S.6
Belmaaza, A.7
Wouters, B.8
Bristow, R.G.9
-
47
-
-
29244439933
-
Hypoxia-induced down-regulation of BRCA1 expression by E2Fs
-
DOI 10.1158/0008-5472.CAN-05-2119
-
Bindra, R. S. et al. Hypoxia-induced down-regulation of BRCA1 expression by E2Fs. Cancer Res. 65, 11597-11604 (2005). (Pubitemid 41821719)
-
(2005)
Cancer Research
, vol.65
, Issue.24
, pp. 11597-11604
-
-
Bindra, R.S.1
Gibson, S.L.2
Meng, A.3
Westermark, U.4
Jasin, M.5
Pierce, A.J.6
Bristow, R.G.7
Classon, M.K.8
Glazer, P.M.9
-
48
-
-
4544324453
-
Down-regulation of Rad51 and decreased homologous recombination in hypoxic cancer cells
-
DOI 10.1128/MCB.24.19.8504-8518.2004
-
Bindra, R. S. et al. Down-regulation of Rad51 and decreased homologous recombination in hypoxic cancer cells. Mol. Cell Biol. 24, 8504-8518 (2004). (Pubitemid 39245072)
-
(2004)
Molecular and Cellular Biology
, vol.24
, Issue.19
, pp. 8504-8518
-
-
Bindra, R.S.1
Schaffer, P.J.2
Meng, A.3
Woo, J.4
Maseide, K.5
Roth, M.E.6
Lizardi, P.7
Hedley, D.W.8
Bristow, R.G.9
Glazer, P.M.10
-
49
-
-
77954358148
-
PTEN loss compromises homologous recombination repair in astrocytes: Implications for glioblastoma therapy with temozolomide or poly(ADP-ribose) polymerase inhibitors
-
McEllin, B. et al. PTEN loss compromises homologous recombination repair in astrocytes: implications for glioblastoma therapy with temozolomide or poly(ADP-ribose) polymerase inhibitors. Cancer Res. 70, 5457-5464 (2010).
-
(2010)
Cancer Res.
, vol.70
, pp. 5457-5464
-
-
McEllin, B.1
-
50
-
-
77149157867
-
Synthetic lethal targeting of PTEN mutant cells with PARP inhibitors
-
Mendes-Pereira, A. M. et al. Synthetic lethal targeting of PTEN mutant cells with PARP inhibitors. EMBO Mol. Med. 1, 315-322 (2009).
-
(2009)
EMBO Mol. Med.
, vol.1
, pp. 315-322
-
-
Mendes-Pereira, A.M.1
-
51
-
-
77958049428
-
PTEN deficiency in endometrioid endometrial adenocarcinomas predicts sensitivity to PARP inhibitors
-
Dedes, K. J. et al. PTEN deficiency in endometrioid endometrial adenocarcinomas predicts sensitivity to PARP inhibitors. Sci. Transl. Med. 2, 53ra75 (2010).
-
(2010)
Sci. Transl. Med.
, vol.2
-
-
Dedes, K.J.1
-
52
-
-
77956294131
-
Targeting EGFR induced oxidative stress by PARP1 inhibition in glioblastoma therapy
-
Nitta, M. et al. Targeting EGFR induced oxidative stress by PARP1 inhibition in glioblastoma therapy. PLoS ONE 5, e10767 (2010).
-
(2010)
PLoS ONE
, vol.5
-
-
Nitta, M.1
-
53
-
-
0030611754
-
Loss of p21(Waf1/Cip1) sensitizes tumors to radiation by an apoptosis- independent mechanism
-
Wouters, B. G., Giaccia, A. J., Denko, N. C. & Brown, J. M. Loss of p21Waf1/Cip1 sensitizes tumors to radiation by an apoptosis-independent mechanism. Cancer Res. 57, 4703-4706 (1997). (Pubitemid 27468970)
-
(1997)
Cancer Research
, vol.57
, Issue.21
, pp. 4703-4706
-
-
Wouters, B.G.1
Giaccia, A.J.2
Denko, N.C.3
Brown, J.M.4
-
54
-
-
0027893001
-
Loss of a p53-associated G1 checkpoint does not decrease cell survival following DNA damage
-
Slichenmyer, W. J., Nelson, W. G., Slebos, R. J. & Kastan, M. B. Loss of a p53-associated G1 checkpoint does not decrease cell survival following DNA damage. Cancer Res. 53, 4164-4168 (1993). (Pubitemid 24146760)
-
(1993)
Cancer Research
, vol.53
, Issue.18
, pp. 4164-4168
-
-
Slichenmyer, W.J.1
Nelson, W.G.2
Slebos, R.J.3
Kastan, M.B.4
-
55
-
-
38949147038
-
G2 checkpoint abrogation and checkpoint kinase-1 targeting in the treatment of cancer
-
DOI 10.1038/sj.bjc.6604208, PII 6604208
-
Bucher, N. & Britten, C. D. G2 checkpoint abrogation and checkpoint kinase-1 targeting in the treatment of cancer. Br. J. Cancer 98, 523-528 (2008). (Pubitemid 351214533)
-
(2008)
British Journal of Cancer
, vol.98
, Issue.3
, pp. 523-528
-
-
Bucher, N.1
Britten, C.D.2
-
56
-
-
9244260517
-
Enhancement of radiation cytotoxicity by UCN-01 in non-small cell lung carcinoma cells
-
Mack, P. C. et al. Enhancement of radiation cytotoxicity by UCN-01 in non-small cell lung carcinoma cells. Radiat. Res. 162, 623-634 (2004).
-
(2004)
Radiat. Res.
, vol.162
, pp. 623-634
-
-
MacK, P.C.1
-
57
-
-
10844237358
-
Inhibition of Chk1 by CEP-3891 accelerates mitotic nuclear fragmentation in response to ionizing radiation
-
DOI 10.1158/0008-5472.CAN-04-2434
-
Syljuasen, R. G. et al. Inhibition of Chk1 by CEP-3891 accelerates mitotic nuclear fragmentation in response to ionizing Radiation. Cancer Res. 64, 9035-9040 (2004). (Pubitemid 39665514)
-
(2004)
Cancer Research
, vol.64
, Issue.24
, pp. 9035-9040
-
-
Syljuasen, R.G.1
Sorensen, C.S.2
Nylandsted, J.3
Lukas, C.4
Lukas, J.5
Bartek, J.6
-
58
-
-
36949012288
-
Targeted cancer therapies based on the inhibition of DNA strand break repair
-
DOI 10.1038/sj.onc.1210879, PII 1210879
-
O'Connor, M. J., Martin, N. M. & Smith, G. C. Targeted cancer therapies based on the inhibition of DNA strand break repair. Oncogene 26, 7816-7824 (2007). (Pubitemid 350242461)
-
(2007)
Oncogene
, vol.26
, Issue.56
, pp. 7816-7824
-
-
O'Connor, M.J.1
Martin, N.M.B.2
Smith, G.C.M.3
-
59
-
-
52949139387
-
AZD7762, a novel checkpoint kinase inhibitor, drives checkpoint abrogation and potentiates DNA-targeted therapies
-
Zabludoff, S. D. et al. AZD7762, a novel checkpoint kinase inhibitor, drives checkpoint abrogation and potentiates DNA-targeted therapies. Mol. Cancer Ther. 7, 2955-2966 (2008).
-
(2008)
Mol. Cancer Ther.
, vol.7
, pp. 2955-2966
-
-
Zabludoff, S.D.1
-
60
-
-
77953770987
-
Mechanism of radiosensitization by the Chk1/2 inhibitor AZD7762 involves abrogation of the G2 checkpoint and inhibition of homologous recombinational DNA repair
-
Morgan, M. A. et al. Mechanism of radiosensitization by the Chk1/2 inhibitor AZD7762 involves abrogation of the G2 checkpoint and inhibition of homologous recombinational DNA repair. Cancer Res. 70, 4972-4981 (2010).
-
(2010)
Cancer Res.
, vol.70
, pp. 4972-4981
-
-
Morgan, M.A.1
-
61
-
-
34250865564
-
CDC25 phosphatases in cancer cells: Key players? Good targets?
-
DOI 10.1038/nrc2169, PII NRC2169
-
Boutros, R., Lobjois, V. & Ducommun, B. CDC25 phosphatases in cancer cells: key players? Good targets? Nature Rev. Cancer 7, 495-507 (2007). (Pubitemid 46985396)
-
(2007)
Nature Reviews Cancer
, vol.7
, Issue.7
, pp. 495-507
-
-
Boutros, R.1
Lobjois, V.2
Ducommun, B.3
-
62
-
-
60549098070
-
CDC25 inhibitors as anticancer agents are moving forward
-
Brezak, M. C., Kasprzyk, P. G., Galcera, M. O., Lavergne, O. & Prevost, G. P. CDC25 inhibitors as anticancer agents are moving forward. Anticancer Agents Med. Chem. 8, 857-862 (2008).
-
(2008)
Anticancer Agents Med. Chem.
, vol.8
, pp. 857-862
-
-
Brezak, M.C.1
Kasprzyk, P.G.2
Galcera, M.O.3
Lavergne, O.4
Prevost, G.-P.5
-
63
-
-
70350238489
-
Improved ATM kinase inhibitor KU-60019 radiosensitizes glioma cells, compromises insulin, AKT and ERK prosurvival signaling, and inhibits migration and invasion
-
Golding, S. E. et al. Improved ATM kinase inhibitor KU-60019 radiosensitizes glioma cells, compromises insulin, AKT and ERK prosurvival signaling, and inhibits migration and invasion. Mol. Cancer Ther. 8, 2894-2902 (2009).
-
(2009)
Mol. Cancer Ther.
, vol.8
, pp. 2894-2902
-
-
Golding, S.E.1
-
64
-
-
65449142073
-
CHK1 inhibition as a strategy for targeting Fanconi Anemia (FA) DNA repair pathway deficient tumors
-
Chen, C. C., Kennedy, R. D., Sidi, S., Look, A. T. & D'Andrea, A. CHK1 inhibition as a strategy for targeting Fanconi Anemia (FA) DNA repair pathway deficient tumors. Mol. Cancer 8, 24 (2009).
-
(2009)
Mol. Cancer
, vol.8
, pp. 24
-
-
Chen, C.C.1
Kennedy, R.D.2
Sidi, S.3
Look, A.T.4
D'Andrea, A.5
-
65
-
-
33845303212
-
Inhibition of transforming growth factor-β1 signaling attenuates ataxia telangiectasia mutated activity in response to genotoxic stress
-
DOI 10.1158/0008-5472.CAN-06-2565
-
Kirshner, J. et al. Inhibition of transforming growth factor-beta1 signaling attenuates ataxia telangiectasia mutated activity in response to genotoxic stress. Cancer Res. 66, 10861-10869 (2006). (Pubitemid 44876983)
-
(2006)
Cancer Research
, vol.66
, Issue.22
, pp. 10861-10869
-
-
Kirshner, J.1
Jobling, M.F.2
Pajares, M.J.3
Ravani, S.A.4
Glick, A.B.5
Lavin, M.J.6
Koslov, S.7
Shiloh, Y.8
Barcellos-Hoff, M.H.9
-
66
-
-
0034644539
-
Cell signaling by receptor tyrosine kinases
-
Schlessinger, J. Cell signaling by receptor tyrosine kinases. Cell 103, 211-225 (2000).
-
(2000)
Cell
, vol.103
, pp. 211-225
-
-
Schlessinger, J.1
-
67
-
-
43049131769
-
Targeting the PI3K/Akt/mTOR pathway: Effective combinations and clinical considerations
-
LoPiccolo, J., Blumenthal, G. M., Bernstein, W. B. & Dennis, P. A. Targeting the PI3K/Akt/mTOR pathway: effective combinations and clinical considerations. Drug Resist. Updat. 11, 32-50 (2008).
-
(2008)
Drug Resist. Updat.
, vol.11
, pp. 32-50
-
-
Lopiccolo, J.1
Blumenthal, G.M.2
Bernstein, W.B.3
Dennis, P.-A.4
-
68
-
-
24744452428
-
Selective inhibition of Ras, phosphoinositide 3 kinase, and Akt isoforms increases the radiosensitivity of human carcinoma cell lines
-
Kim, I. A. et al. Selective inhibition of Ras, phosphoinositide 3 kinase, and Akt isoforms increases the radiosensitivity of human carcinoma cell lines. Cancer Res. 65, 7902-7910 (2005).
-
(2005)
Cancer Res.
, vol.65
, pp. 7902-7910
-
-
Kim, I.A.1
-
69
-
-
32144433159
-
Radiotherapy plus cetuximab for squamous-cell carcinoma of the head and neck
-
DOI 10.1056/NEJMoa053422
-
Bonner, J. A. et al. Radiotherapy plus cetuximab for squamous-cell carcinoma of the head and neck. N.-Engl. J. Med. 354, 567-578 (2006). (Pubitemid 43209104)
-
(2006)
New England Journal of Medicine
, vol.354
, Issue.6
, pp. 567-578
-
-
Bonner, J.A.1
Harari, P.M.2
Giralt, J.3
Azarnia, N.4
Shin, D.M.5
Cohen, R.B.6
Jones, C.U.7
Sur, R.8
Raben, D.9
Jassem, J.10
Ove, R.11
Kies, M.S.12
Baselga, J.13
Youssoufian, H.14
Amellal, N.15
Rowinsky, E.K.16
Ang, K.K.17
-
70
-
-
73249143536
-
Radiotherapy plus cetuximab for locoregionally advanced head and neck cancer: 5-year survival data from a phase 3 randomised trial, and relation between cetuximab-induced rash and survival
-
Bonner, J. A. et al. Radiotherapy plus cetuximab for locoregionally advanced head and neck cancer: 5-year survival data from a phase 3 randomised trial, and relation between cetuximab-induced rash and survival. Lancet Oncol. 11, 21-28 (2010).
-
(2010)
Lancet Oncol.
, vol.11
, pp. 21-28
-
-
Bonner, J.A.1
-
71
-
-
0036795061
-
Enhancement of antitumor activity of ionizing radiation by combined treatment with the selective epidermal growth factor receptor-tyrosine kinase inhibitor ZD1839 (Iressa)
-
Bianco, C. et al. Enhancement of antitumor activity of ionizing radiation by combined treatment with the selective epidermal growth factor receptor-tyrosine kinase inhibitor ZD1839 (Iressa). Clin. Cancer Res. 8, 3250-3258 (2002). (Pubitemid 35155038)
-
(2002)
Clinical Cancer Research
, vol.8
, Issue.10
, pp. 3250-3258
-
-
Bianco, C.1
Tortora, G.2
Bianco, R.3
Caputo, R.4
Veneziani, B.M.5
Caputo, R.6
Damiano, V.7
Troiani, T.8
Fontanini, G.9
Raben, D.10
Pepe, S.11
Bianco, A.R.12
Ciardiello, F.13
-
72
-
-
34247877768
-
Effect of epidermal growth factor receptor inhibitor class in the treatment of head and neck cancer with concurrent radiochemotherapy in vivo
-
DOI 10.1158/1078-0432.CCR-06-2582
-
Feng, F. Y. et al. Effect of epidermal growth factor receptor inhibitor class in the treatment of head and neck cancer with concurrent radiochemotherapy in vivo. Clin. Cancer Res. 13, 2512-2518 (2007). (Pubitemid 46698604)
-
(2007)
Clinical Cancer Research
, vol.13
, Issue.8
, pp. 2512-2518
-
-
Feng, F.Y.1
Lopez, C.A.2
Normolle, D.P.3
Varambally, S.4
Li, X.5
Chun, P.Y.6
Davis, M.A.7
Lawrence, T.S.8
Nyati, M.K.9
-
73
-
-
70449509655
-
Heterogeneity of tumour response to combined radiotherapy and EGFR inhibitors: Differences between antibodies and TK inhibitors
-
Krause, M., Gurtner, K., Deuse, Y. & Baumann, M. Heterogeneity of tumour response to combined radiotherapy and EGFR inhibitors: differences between antibodies and TK inhibitors. Int. J. Radiat. Biol. 85, 943-954 (2009).
-
(2009)
Int. J. Radiat. Biol.
, vol.85
, pp. 943-954
-
-
Krause, M.1
Gurtner, K.2
Deuse, Y.3
Baumann, M.4
-
74
-
-
0035341494
-
Enhancement of radiosensitivity by proteasome inhibition: Implications for a role of NF-κB
-
Russo, S. M. et al. Enhancement of radiosensitivity by proteasome inhibition: implications for a role of NF-κB. Int. J. Radiat. Oncol. Biol. Phys. 50, 183-193 (2001).
-
(2001)
Int. J. Radiat. Oncol. Biol. Phys.
, vol.50
, pp. 183-193
-
-
Russo, S.M.1
-
75
-
-
77649341172
-
Targeting transcription factor NF-κB to overcome chemoresistance and radioresistance in cancer therapy
-
Li, F. & Sethi, G. Targeting transcription factor NF-κB to overcome chemoresistance and radioresistance in cancer therapy. Biochim. Biophys. Acta. 1805, 167-180 (2010).
-
(2010)
Biochim. Biophys. Acta.
, vol.1805
, pp. 167-180
-
-
Li, F.1
Sethi, G.2
-
76
-
-
16844366650
-
Nuclear factor-κB inhibitors as sensitizers to anticancer drugs
-
DOI 10.1038/nrc1588
-
Nakanishi, C. & Toi, M. Nuclear factor-κB inhibitors as sensitizers to anticancer drugs. Nature Rev. Cancer. 5, 297-309 (2005). (Pubitemid 40488635)
-
(2005)
Nature Reviews Cancer
, vol.5
, Issue.4
, pp. 297-309
-
-
Nakanishi, C.1
Toi, M.2
-
77
-
-
60149100173
-
Ionizing radiation-induced NF-kappaB activation requires PARP-1 function to confer radioresistance
-
Veuger, S. J., Hunter, J. E. & Durkacz, B. W. Ionizing radiation-induced NF-kappaB activation requires PARP-1 function to confer radioresistance. Oncogene 28, 832-842 (2009).
-
(2009)
Oncogene
, vol.28
, pp. 832-842
-
-
Veuger, S.J.1
Hunter, J.E.2
Durkacz, B.W.3
-
78
-
-
63849257538
-
Induction of autophagic cell death and radiosensitization by the pharmacological inhibition of nuclear factor-kappa B activation in human glioma cell lines
-
Tsuboi, Y. et al. Induction of autophagic cell death and radiosensitization by the pharmacological inhibition of nuclear factor-kappa B activation in human glioma cell lines. J.-Neurosurg. 110, 594-604 (2009).
-
(2009)
J.-Neurosurg.
, vol.110
, pp. 594-604
-
-
Tsuboi, Y.1
-
79
-
-
69549084702
-
Curcumin modulates the radiosensitivity of colorectal cancer cells by suppressing constitutive and inducible NF-kappaB activity
-
Sandur, S. K. et al. Curcumin modulates the radiosensitivity of colorectal cancer cells by suppressing constitutive and inducible NF-kappaB activity. Int. J. Radiat. Oncol. Biol. Phys. 75, 534-542 (2009).
-
(2009)
Int. J. Radiat. Oncol. Biol. Phys.
, vol.75
, pp. 534-542
-
-
Sandur, S.K.1
-
80
-
-
33847066413
-
Extracellular signal-related kinase positively regulates ataxia telangiectasia mutated, homologous recombination repair, and the DNA damage response
-
Golding, S. E. et al. Extracellular signal-related kinase positively regulates ataxia telangiectasia mutated, homologous recombination repair, and the DNA damage response. Cancer Res. 67, 1046-1053 (2007).
-
(2007)
Cancer Res.
, vol.67
, pp. 1046-1053
-
-
Golding, S.E.1
-
81
-
-
77955277480
-
The epidermal growth factor receptor modulates DNA double-strand break repair by regulating non-homologous end-joining
-
Kriegs, M. et al. The epidermal growth factor receptor modulates DNA double-strand break repair by regulating non-homologous end-joining. DNA Repair (Amst). 9, 889-897 (2010).
-
(2010)
DNA Repair (Amst).
, vol.9
, pp. 889-897
-
-
Kriegs, M.1
-
82
-
-
36849026669
-
New rationales for using TGFβ inhibitors in radiotherapy
-
DOI 10.1080/09553000701711063, PII 783640046
-
Andarawewa, K. L., Paupert, J., Pal, A. & Barcellos-Hoff, M. H. New rationales for using TGFbeta inhibitors in radiotherapy. Int. J. Radiat. Biol. 83, 803-811 (2007). (Pubitemid 350219100)
-
(2007)
International Journal of Radiation Biology
, vol.83
, Issue.11-12
, pp. 803-811
-
-
Andarawewa, K.L.1
Paupert, J.2
Pal, A.3
Barcellos-Hoff, M.H.4
-
83
-
-
34250189244
-
TGFβ-1 dependent fast stimulation of ATM and p53 phosphorylation following exposure to ionizing radiation does not involve TGFβ-receptor I signalling
-
DOI 10.1016/j.radonc.2007.05.013, PII S0167814007001909, Highlights from the 10th International ESTRO-Wolfsberg Meeting on Molecular Radiation Biology/Oncology 2007
-
Wiegman, E. M., Blaese, M. A., Loeffler, H., Coppes, R. P. & Rodemann, H. P. TGFbeta-1 dependent fast stimulation of ATM and p53 phosphorylation following exposure to ionizing radiation does not involve TGFbeta-receptor I signalling. Radiother. Oncol. 83, 289-295 (2007). (Pubitemid 46907986)
-
(2007)
Radiotherapy and Oncology
, vol.83
, Issue.3
, pp. 289-295
-
-
Wiegman, E.M.1
Blaese, M.A.2
Loeffler, H.3
Coppes, R.P.4
Rodemann, H.P.5
-
84
-
-
0141757460
-
MAPK pathways in radiation responses
-
DOI 10.1038/sj.onc.1206701
-
Dent, P., Yacoub, A., Fisher, P. B., Hagan, M. P. & Grant, S. MAPK pathways in radiation responses. Oncogene 22, 5885-5896 (2003). (Pubitemid 37176709)
-
(2003)
Oncogene
, vol.22
, Issue.37 REV. ISSUE 3
, pp. 5885-5896
-
-
Dent, P.1
Yacoub, A.2
Fisher, P.B.3
Hagan, M.P.4
Grant, S.5
-
85
-
-
0029976817
-
An essential role for NF-κB in preventing TNF-α-induced cell death
-
DOI 10.1126/science.274.5288.782
-
Beg, A. A. & Baltimore, D. An essential role for NF-kappaB in preventing TNF-alpha-induced cell death. Science. 274, 782-784 (1996). (Pubitemid 26398258)
-
(1996)
Science
, vol.274
, Issue.5288
, pp. 782-784
-
-
Beg, A.A.1
Baltimore, D.2
-
86
-
-
14644407525
-
The role of apoptosis in cancer development and treatment response
-
DOI 10.1038/nrc1570
-
Brown, J. M. & Attardi, L. D. The role of apoptosis in cancer development and treatment response. Nature Rev. Cancer 5, 231-237 (2005). (Pubitemid 40314954)
-
(2005)
Nature Reviews Cancer
, vol.5
, Issue.3
, pp. 231-237
-
-
Brown, J.M.1
Attardi, L.D.2
-
87
-
-
33746088022
-
Blockage of epidermal growth factor receptor-phosphatidylinositol 3-kinase-AKT signaling increases radiosensitivity of K-RAS mutated human tumor cells in vitro by affecting DNA repair
-
DOI 10.1158/1078-0432.CCR-05-2454
-
Toulany, M. et al. Blockage of epidermal growth factor receptor-phosphatidylinositol 3-kinase-AKT signaling increases radiosensitivity of K-RAS mutated human tumor cells in vitro by affecting DNA repair. Clin. Cancer Res. 12, 4119-4126 (2006). (Pubitemid 44078101)
-
(2006)
Clinical Cancer Research
, vol.12
, Issue.13
, pp. 4119-4126
-
-
Toulany, M.1
Kasten-Pisula, U.2
Brammer, I.3
Wang, S.4
Chen, J.5
Dittmann, K.6
Baumann, M.7
Dikomey, E.8
Rodemann, H.P.9
-
88
-
-
24744449739
-
Radiation-induced epidermal growth factor receptor nuclear import is linked to activation of DNA-dependent protein kinase
-
DOI 10.1074/jbc.M506591200
-
Dittmann, K. et al. Radiation-induced epidermal growth factor receptor nuclear import is linked to activation of DNA-dependent protein kinase. J.-Biol. Chem. 280, 31182-31189 (2005). (Pubitemid 41291855)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.35
, pp. 31182-31189
-
-
Dittmann, K.1
Mayer, C.2
Fehrenbacher, B.3
Schaller, M.4
Raju, U.5
Milas, L.6
Chen, D.J.7
Kehlbach, R.8
Rodemann, H.P.9
-
89
-
-
34547121206
-
Hypoxia in cancer: Significance and impact on clinical outcome
-
DOI 10.1007/s10555-007-9055-1, Special issue on Hypoxia and Cancer, Guest Editor: Gregg L. Semenza
-
Vaupel, P. & Mayer, A. Hypoxia in cancer: significance and impact on clinical outcome. Cancer Metastasis Rev. 26, 225-239 (2007). (Pubitemid 47101660)
-
(2007)
Cancer and Metastasis Reviews
, vol.26
, Issue.2
, pp. 225-239
-
-
Vaupel, P.1
Mayer, A.2
-
90
-
-
0030926491
-
Cells at intermediate oxygen levels can be more important than the 'hypoxic fraction' in determining tumor response to fractionated radiotherapy
-
Wouters, B. G. & Brown, J. M. Cells at intermediate oxygen levels can be more important than the "hypoxic fraction" in determining tumor response to fractionated radiotherapy. Radiat. Res. 147, 541-550 (1997). (Pubitemid 27204090)
-
(1997)
Radiation Research
, vol.147
, Issue.5
, pp. 541-550
-
-
Wouters, B.G.1
Brown, J.M.2
-
91
-
-
35148881028
-
Drug resistance and the solid tumor microenvironment
-
Tredan, O., Galmarini, C. M., Patel, K. & Tannock, I. F. Drug resistance and the solid tumor microenvironment. J. Natl. Cancer Inst. 99, 1441-1454 (2007).
-
(2007)
J. Natl. Cancer Inst.
, vol.99
, pp. 1441-1454
-
-
Tredan, O.1
Galmarini, C.M.2
Patel, K.3
Tannock, I.-F.4
-
92
-
-
0029051439
-
Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension
-
Wang, G. L., Jiang, B. H., Rue, E. A. & Semenza, G. L. Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension. Proc. Natl Acad. Sci. USA 92, 5510-5514 (1995).
-
(1995)
Proc. Natl Acad. Sci. USA
, vol.92
, pp. 5510-5514
-
-
Wang, G.L.1
Jiang, B.H.2
Rue, E.A.3
Semenza, G.-L.4
-
93
-
-
68349135032
-
Regulation of autophagy through multiple independent hypoxic signaling pathways
-
Rouschop, K. M. & Wouters, B. G. Regulation of autophagy through multiple independent hypoxic signaling pathways. Curr. Mol. Med. 9, 417-424 (2009).
-
(2009)
Curr. Mol. Med.
, vol.9
, pp. 417-424
-
-
Rouschop, K.M.1
Wouters, B.-G.2
-
94
-
-
33644551073
-
Gene expression programs in response to hypoxia: Cell type specificity and prognostic significance in human cancers
-
Chi, J. T. et al. Gene expression programs in response to hypoxia: cell type specificity and prognostic significance in human cancers. PLoS Med. 3, e47 (2006).
-
(2006)
PLoS Med.
, vol.3
-
-
Chi, J.T.1
-
95
-
-
34248172298
-
Relation of a hypoxia metagene derived from head and neck cancer to prognosis of multiple cancers
-
DOI 10.1158/0008-5472.CAN-06-3322
-
Winter, S. C. et al. Relation of a hypoxia metagene derived from head and neck cancer to prognosis of multiple cancers. Cancer Res. 67, 3441-3449 (2007). (Pubitemid 46724885)
-
(2007)
Cancer Research
, vol.67
, Issue.7
, pp. 3441-3449
-
-
Winter, S.C.1
Buffa, F.M.2
Silva, P.3
Miller, C.4
Valentine, H.R.5
Turley, H.6
Shah, K.A.7
Cox, G.J.8
Corbridge, R.J.9
Homer, J.J.10
Musgrove, B.11
Slevin, N.12
Sloan, P.13
Price, P.14
West, C.M.L.15
Harris, A.L.16
-
96
-
-
34250323878
-
Impact of supervised gene signatures of early hypoxia on patient survival
-
DOI 10.1016/j.radonc.2007.05.002, PII S0167814007001843, Highlights from the 10th International ESTRO-Wolfsberg Meeting on Molecular Radiation Biology/Oncology 2007
-
Seigneuric, R. et al. Impact of supervised gene signatures of early hypoxia on patient survival. Radiother. Oncol. 83, 374-382 (2007). (Pubitemid 46915549)
-
(2007)
Radiotherapy and Oncology
, vol.83
, Issue.3
, pp. 374-382
-
-
Seigneuric, R.1
Starmans, M.H.W.2
Fung, G.3
Krishnapuram, B.4
Nuyten, D.S.A.5
Van Erk, A.6
Magagnin, M.G.7
Rouschop, K.M.8
Krishnan, S.9
Rao, R.B.10
Evelo, C.T.A.11
Begg, A.C.12
Wouters, B.G.13
Lambin, P.14
-
97
-
-
0025939872
-
A therapeutic benefit from combining normobaric carbogen or oxygen with nicotinamide in fractionated X-ray treatments
-
Kjellen, E., Joiner, M. C., Collier, J. M., Johns, H. & Rojas, A. A therapeutic benefit from combining normobaric carbogen or oxygen with nicotinamide in fractionated X-ray treatments. Radiother. Oncol. 22, 81-91 (1991).
-
(1991)
Radiother. Oncol.
, vol.22
, pp. 81-91
-
-
Kjellen, E.1
Joiner, M.C.2
Collier, J.M.3
Johns, H.4
Rojas, A.5
-
98
-
-
0036898268
-
ARCON: A novel biology-based approach in radiotherapy
-
DOI 10.1016/S1470-2045(02)00929-4
-
Kaanders, J. H., Bussink, J. & van der Kogel, A. J. ARCON: a novel biology-based approach in radiotherapy. Lancet Oncol. 3, 728-737 (2002). (Pubitemid 35446742)
-
(2002)
Lancet Oncology
, vol.3
, Issue.12
, pp. 728-737
-
-
Kaanders, J.H.A.M.1
Bussink, J.2
Van Der Kogel, A.J.3
-
99
-
-
0026580317
-
Carbogen breathing: A system for use in man
-
Dische, S., Rojas, A., Rugg, T., Hong, A. & Michael, B. D. Carbogen breathing: a system for use in man. Br. J. Radiol. 65, 87-90 (1992).
-
(1992)
Br. J. Radiol.
, vol.65
, pp. 87-90
-
-
Dische, S.1
Rojas, A.2
Rugg, T.3
Hong, A.4
Michael, B.-D.5
-
100
-
-
0027717135
-
A convenient and reliable method for carbogen breathing in man
-
DOI 10.1016/0167-8140(93)90153-Y
-
Kaanders, J. H. & van der Maazen, R. W. A convenient and reliable method for carbogen breathing in man. Radiother. Oncol. 29, 341-343 (1993). (Pubitemid 24025356)
-
(1993)
Radiotherapy and Oncology
, vol.29
, Issue.3
, pp. 341-343
-
-
Kaanders, J.H.A.M.1
-
101
-
-
0027373144
-
Enhanced oxygenation in vivo by allosteric inhibitors of hemoglobin saturation
-
Khandelwal, S. R. et al. Enhanced oxygenation in vivo by allosteric inhibitors of hemoglobin saturation. Am. J.-Physiol. 265, H1450-H1453 (1993). (Pubitemid 23327742)
-
(1993)
American Journal of Physiology - Heart and Circulatory Physiology
, vol.265
, Issue.4
-
-
Khandelwal, S.R.1
Randad, R.S.2
Lin, P.-S.3
Meng, H.4
Pittman, R.N.5
Kontos, H.A.6
Choi, S.C.7
Abraham, D.J.8
Schmidt-Ullrich, R.9
-
102
-
-
0034875068
-
Enhancement of tumor oxygenation and radiation response by the allosteric effector of hemoglobin, RSR13
-
Amorino, G. P. et al. Enhancement of tumor oxygenation and radiation response by the allosteric effector of hemoglobin, RSR13. Radiat. Res. 156, 294-300 (2001). (Pubitemid 32801098)
-
(2001)
Radiation Research
, vol.156
, Issue.3
, pp. 294-300
-
-
Amorino, G.P.1
Lee, H.2
Holburn, G.E.3
Paschal, C.B.4
Hercules, S.K.5
Shyr, Y.6
Steffen, R.P.7
Choy, H.8
-
103
-
-
37349077910
-
Improved survival, quality of life, and quality-adjusted survival in breast cancer patients treated with efaproxiral (Efaproxyn) plus whole-brain radiation therapy for brain metastases
-
DOI 10.1097/COC.0b013e3180653c0d, PII 0000042120071200000004
-
Scott, C., Suh, J., Stea, B., Nabid, A. & Hackman, J. Improved survival, quality of life, and quality-adjusted survival in breast cancer patients treated with efaproxiral (Efaproxyn) plus whole-brain radiation therapy for brain metastases. Am. J. Clin. Oncol. 30, 580-587 (2007). (Pubitemid 350307182)
-
(2007)
American Journal of Clinical Oncology: Cancer Clinical Trials
, vol.30
, Issue.6
, pp. 580-587
-
-
Scott, C.1
Suh, J.2
Stea, B.3
Nabid, A.4
Hackman, J.5
-
104
-
-
0031909654
-
A randomized double-blind phase III study of nimorazole as a hypoxic radiosensitizer of primary radiotherapy in supraglottic larynx and pharynx carcinoma. Results of the Danish Head and Neck Cancer Study (DAHANCA) Protocol 5-85
-
DOI 10.1016/S0167-8140(97)00220-X, PII S016781409700220X
-
Overgaard, J. et al. A randomized double-blind phase III study of nimorazole as a hypoxic radiosensitizer of primary radiotherapy in supraglottic larynx and pharynx carcinoma. Results of the Danish Head and Neck Cancer Study (DAHANCA) Protocol 5-85 Radiother. Oncol. 46, 135-146 (1998). (Pubitemid 28109172)
-
(1998)
Radiotherapy and Oncology
, vol.46
, Issue.2
, pp. 135-146
-
-
Overgaard, J.1
Hansen, H.S.2
Overgaard, M.3
Bastholt, L.4
Berthelsen, A.5
Specht, L.6
Lindelov, B.7
Jorgensen, K.8
-
105
-
-
77956529790
-
Stereotactic ablative radiotherapy should be combined with a hypoxic cell radiosensitizer
-
Brown, J. M., Diehn, M. & Loo, B. W. Jr. Stereotactic ablative radiotherapy should be combined with a hypoxic cell radiosensitizer. Int. J. Radiat. Oncol. Biol. Phys. 78, 323-327 (2010).
-
(2010)
Int. J. Radiat. Oncol. Biol. Phys.
, vol.78
, pp. 323-327
-
-
Brown, J.M.1
Diehn, M.2
Loo Jr., B.W.3
-
106
-
-
0026417645
-
Therapeutic advantage of hypoxic cells in tumors: A theoretical study
-
Brown, J. M. & Koong, A. Therapeutic advantage of hypoxic cells in tumors: a theoretical study. J. Natl. Cancer Inst. 83, 178-185 (1991).
-
(1991)
J. Natl. Cancer Inst.
, vol.83
, pp. 178-185
-
-
Brown, J.M.1
Koong, A.2
-
107
-
-
77954600498
-
Tirapazamine, cisplatin, and radiation versus cisplatin and radiation for advanced squamous cell carcinoma of the head and neck (TROG 02.02, HeadSTART): A phase III trial of the Trans-Tasman Radiation Oncology Group
-
Rischin, D. et al. Tirapazamine, cisplatin, and radiation versus cisplatin and radiation for advanced squamous cell carcinoma of the head and neck (TROG 02.02, HeadSTART): a phase III trial of the Trans-Tasman Radiation Oncology Group. J. Clin. Oncol. 28, 2989-2995 (2010).
-
(2010)
J. Clin. Oncol.
, vol.28
, pp. 2989-2995
-
-
Rischin, D.1
-
108
-
-
77958060317
-
Pharmacokinetic/pharmacodynamic modeling identifies SN30000 and SN29751 as tirapazamine analogues with improved tissue penetration and hypoxic cell killing in tumors
-
Hicks, K. O. et al. Pharmacokinetic/pharmacodynamic modeling identifies SN30000 and SN29751 as tirapazamine analogues with improved tissue penetration and hypoxic cell killing in tumors. Clin. Cancer Res. 16, 4946-4957 (2010).
-
(2010)
Clin. Cancer Res.
, vol.16
, pp. 4946-4957
-
-
Hicks, K.O.1
-
109
-
-
74949118681
-
The unfolded protein response protects human tumor cells during hypoxia through regulation of the autophagy genes MAP1LC3B and ATG5
-
Rouschop, K. M. et al. The unfolded protein response protects human tumor cells during hypoxia through regulation of the autophagy genes MAP1LC3B and ATG5. J. Clin. Invest. 120, 127-141 (2010).
-
(2010)
J. Clin. Invest.
, vol.120
, pp. 127-141
-
-
Rouschop, K.M.1
-
110
-
-
68049144956
-
Tumor vascular changes mediated by inhibition of oncogenic signaling
-
Qayum, N. et al. Tumor vascular changes mediated by inhibition of oncogenic signaling. Cancer Res. 69, 6347-6354 (2009).
-
(2009)
Cancer Res.
, vol.69
, pp. 6347-6354
-
-
Qayum, N.1
-
111
-
-
0035266246
-
The farnesyltransferase inhibitor L744,832 reduces hypoxia in tumors expressing activated H-ras
-
Cohen-Jonathan, E. et al. The farnesyltransferase inhibitor L744,832 reduces hypoxia in tumors expressing activated H-ras. Cancer Res. 61, 2289-2293 (2001). (Pubitemid 32692061)
-
(2001)
Cancer Research
, vol.61
, Issue.5
, pp. 2289-2293
-
-
Cohen-Jonathan, E.1
Evans, S.M.2
Koch, C.J.3
Muschel, R.J.4
McKenna, W.G.5
Wu, J.6
Bernhard, E.J.7
-
112
-
-
0032581277
-
Role of HIF-1α in hypoxiamediated apoptosis, cell proliferation and tumour angiogenesis
-
DOI 10.1038/28867
-
Carmeliet, P. et al. Role of HIF-1alpha in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis. Nature 394, 485-490 (1998). (Pubitemid 28373960)
-
(1998)
Nature
, vol.394
, Issue.6692
, pp. 485-490
-
-
Carmeliet, P.1
Dor, Y.2
Herber, J.-M.3
Fukumura, D.4
Brusselmans, K.5
Dewerchin, M.6
Neeman, M.7
Bono, F.8
Abramovitch, R.9
Maxwell, P.10
Koch, C.J.11
Ratcliffe, P.12
Moons, L.13
Jain, R.K.14
Collen, D.15
Keshet, E.16
-
113
-
-
65949123145
-
Influence of bone marrow-derived hematopoietic cells on the tumor response to radiotherapy: Experimental models and clinical perspectives
-
Ahn, G. O. & Brown, J. M. Influence of bone marrow-derived hematopoietic cells on the tumor response to radiotherapy: experimental models and clinical perspectives. Cell Cycle. 8, 970-976 (2009).
-
(2009)
Cell Cycle.
, vol.8
, pp. 970-976
-
-
Ahn, G.O.1
Brown, J.M.2
-
114
-
-
67650742630
-
Role of endothelial progenitors and other bone marrow-derived cells in the development of the tumor vasculature
-
Ahn, G. O. & Brown, J. M. Role of endothelial progenitors and other bone marrow-derived cells in the development of the tumor vasculature. Angiogenesis. 12, 159-164 (2009).
-
(2009)
Angiogenesis.
, vol.12
, pp. 159-164
-
-
Ahn, G.O.1
Brown, J.M.2
-
115
-
-
39849100541
-
Matrix metalloproteinase-9 is required for tumor vasculogenesis but not for angiogenesis: Role of bone marrow-derived myelomonocytic cells
-
DOI 10.1016/j.ccr.2007.11.032, PII S1535610808000020
-
Ahn, G. O. & Brown, J. M. Matrix metalloproteinase-9 is required for tumor vasculogenesis but not for angiogenesis: role of bone marrow-derived myelomonocytic cells. Cancer Cell 13, 193-205 (2008). (Pubitemid 351318369)
-
(2008)
Cancer Cell
, vol.13
, Issue.3
, pp. 193-205
-
-
Ahn, G.-O.1
Brown, J.M.2
-
116
-
-
0038626211
-
Tumor response to radiotherapy regulated by endothelial cell apoptosis
-
DOI 10.1126/science.1082504
-
Garcia-Barros, M. et al. Tumor response to radiotherapy regulated by endothelial cell apoptosis. Science 300, 1155-1159 (2003). (Pubitemid 36583102)
-
(2003)
Science
, vol.300
, Issue.5622
, pp. 1155-1159
-
-
Garcia-Barros, M.1
Paris, F.2
Cordon-Cardo, C.3
Lyden, D.4
Rafii, S.5
Haimovitz-Friedman, A.6
Fuks, Z.7
Kolesnick, R.8
-
117
-
-
9244246263
-
Models for evaluating agents intended for the prophylaxis, mitigation and treatment of radiation injuries report of an NCI workshop, December 3-4, 2003
-
DOI 10.1667/RR3276
-
Stone, H. B. et al. Models for evaluating agents intended for the prophylaxis, mitigation and treatment of radiation injuries. Report of an NCI Workshop, December 3-4, 2003. Radiat. Res. 162, 711-728 (2004). (Pubitemid 39552901)
-
(2004)
Radiation Research
, vol.162
, Issue.6
, pp. 711-728
-
-
Stone, H.B.1
Moulder, J.E.2
Coleman, C.N.3
Ang, K.K.4
Anscher, M.S.5
Barcellos-Hoff, M.H.6
Dynan, W.S.7
Fike, J.R.8
Grdina, D.J.9
Greenberger, J.S.10
Hauer-Jensen, M.11
Hill, R.P.12
Kolesnick, R.N.13
MacVittie, T.J.14
Marks, C.15
McBride, W.H.16
Metting, N.17
Pellmar, T.18
Purucker, M.19
Robbins, M.E.20
Schiestl, R.H.21
Seed, T.M.22
Tomaszewski, J.E.23
Travis, E.L.24
Wallner, P.E.25
Wolpert, M.26
Zaharevitz, D.27
more..
-
118
-
-
0000416892
-
Cysteine protection against X irradiation
-
Patt, H. M., Tyree, E. B., Straube, R. L. & Smith, D. E. Cysteine protection against X irradiation. Science 110, 213-214 (1949).
-
(1949)
Science
, vol.110
, pp. 213-214
-
-
Patt, H.M.1
Tyree, E.B.2
Straube, R.L.3
Smith, D.E.4
-
119
-
-
67651176009
-
History and development of radiation-protective agents
-
Weiss, J. F. & Landauer, M. R. History and development of radiation-protective agents. Int. J. Radiat. Biol. 85, 539-573 (2009).
-
(2009)
Int. J. Radiat. Biol.
, vol.85
, pp. 539-573
-
-
Weiss, J.F.1
Landauer, M.R.2
-
120
-
-
0019985141
-
Radioprotection of mouse skin by WR-2721: The critical influence of oxygen tension
-
Denekamp, J., Michael, B. D., Rojas, A. & Stewart, F. A. Radioprotection of mouse skin by WR-2721: the critical influence of oxygen tension. Int. J. Radiat. Oncol. Biol. Phys. 8, 531-534 (1982). (Pubitemid 12090574)
-
(1982)
International Journal of Radiation Oncology Biology Physics
, vol.8
, Issue.3-4
, pp. 531-534
-
-
Denekamp, J.1
Michael, B.D.2
Rojas, A.3
Stewart, F.A.4
-
121
-
-
58149335531
-
American Society of Clinical Oncology 2008 clinical practice guideline update: Use of chemotherapy and radiation therapy protectants
-
Hensley, M. L. et al. American Society of Clinical Oncology 2008 clinical practice guideline update: use of chemotherapy and radiation therapy protectants. J. Clin. Oncol. 27, 127-145 (2009).
-
(2009)
J. Clin. Oncol.
, vol.27
, pp. 127-145
-
-
Hensley, M.L.1
-
122
-
-
0042383184
-
Effect of amifostine on toxicities associated with radiochemotherapy in patients with locally advanced non-small-cell lung cancer
-
DOI 10.1016/S0360-3016(03)00590-X
-
Antonadou, D. et al. Effect of amifostine on toxicities associated with radiochemotherapy in patients with locally advanced non-small-cell lung cancer. Int. J. Radiat. Oncol. Biol. Phys. 57, 402-408 (2003). (Pubitemid 37040936)
-
(2003)
International Journal of Radiation Oncology Biology Physics
, vol.57
, Issue.2
, pp. 402-408
-
-
Antonadou, D.1
Throuvalas, N.2
Petridis, A.3
Bolanos, N.4
Sagriotis, A.5
Synodinou, M.6
-
123
-
-
12144286602
-
Effects of amifostine on acute toxicity from concurrent chemotherapy and radiotherapy for inoperable non-small-cell lung cancer: Report of a randomized comparative trial
-
DOI 10.1016/j.ijrobp.2003.10.005, PII S0360301603020935
-
Komaki, R. et al. Effects of amifostine on acute toxicity from concurrent chemotherapy and radiotherapy for inoperable non-small-cell lung cancer: report of a randomized comparative trial. Int. J. Radiat. Oncol. Biol. Phys. 58, 1369-1377 (2004). (Pubitemid 38438296)
-
(2004)
International Journal of Radiation Oncology Biology Physics
, vol.58
, Issue.5
, pp. 1369-1377
-
-
Komaki, R.1
Lee, J.S.2
Milas, L.3
Lee, H.K.4
Fossella, F.V.5
Herbst, R.S.6
Allen, P.K.7
Liao, Z.8
Stevens, C.W.9
Lu, C.10
Zinner, R.G.11
Papadimitrakopoulou, V.A.12
Kies, M.S.13
Blumenschein Jr., G.R.14
Pisters, K.M.15
Glisson, B.S.16
Kurie, J.17
Kaplan, B.18
Garza, V.P.19
Mooring, D.20
Tucker, S.L.21
Cox, J.D.22
more..
-
124
-
-
0037268373
-
Chemical radioprotection: A critical review of amifostine as a cytoprotector in radiotherapy
-
DOI 10.1053/srao.2003.50006
-
Andreassen, C. N., Grau, C. & Lindegaard, J. C. Chemical radioprotection: a critical review of amifostine as a cytoprotector in radiotherapy. Semin. Radiat. Oncol. 13, 62-72 (2003). (Pubitemid 36173261)
-
(2003)
Seminars in Radiation Oncology
, vol.13
, Issue.1
, pp. 62-72
-
-
Andreassen, C.N.1
Grau, C.2
Lindegaard, J.C.3
-
125
-
-
28944446549
-
Reduction of oral mucositis by palifermin (rHuKGF): Dose-effect of rHuKGF
-
DOI 10.1080/09553000500196136
-
Dorr, W., Heider, K. & Spekl, K. Reduction of oral mucositis by palifermin (rHuKGF): dose-effect of rHuKGF. Int. J. Radiat. Biol. 81, 557-565 (2005). (Pubitemid 41784877)
-
(2005)
International Journal of Radiation Biology
, vol.81
, Issue.8
, pp. 557-565
-
-
Dorr, W.1
Heider, K.2
Spekl, K.3
-
126
-
-
0032030965
-
Keratinocyte growth factor protects mice from chemotherapy and radiation-induced gastrointestinal injury and mortality
-
Farrell, C. L. et al. Keratinocyte growth factor protects mice from chemotherapy and radiation-induced gastrointestinal injury and mortality. Cancer Res. 58, 933-939 (1998). (Pubitemid 28182461)
-
(1998)
Cancer Research
, vol.58
, Issue.5
, pp. 933-939
-
-
Farrell, C.L.1
Bready, J.V.2
Rex, K.L.3
Chen, J.N.4
DiPalma, C.R.5
Whitcomb, K.L.6
Yin, S.7
Hill, D.C.8
Wiemann, B.9
Starnes, C.O.10
Havill, A.M.11
Lu, Z.-N.12
Aukerman, S.L.13
Pierce, G.F.14
Thomason, A.15
Potten, C.S.16
Ulich, T.R.17
Lacey, D.L.18
-
127
-
-
0030868946
-
Enhancement of murine intestinal stem cell survival after irradiation by keratinocyte growth factor
-
DOI 10.2307/3579609
-
Khan, W. B., Shui, C., Ning, S. & Knox, S. J. Enhancement of murine intestinal stem cell survival after irradiation by keratinocyte growth factor. Radiat. Res. 148, 248-253 (1997). (Pubitemid 27374102)
-
(1997)
Radiation Research
, vol.148
, Issue.3
, pp. 248-253
-
-
Khan, W.B.1
Shui, C.2
Ning, S.3
Knox, S.J.4
-
128
-
-
10044275308
-
The protective effect of recombinant human keratinocyte growth factor on radiation-induced pulmonary toxicity in rats
-
DOI 10.1016/j.ijrobp.2004.07.729, PII S0360301604025751
-
Chen, L. et al. The protective effect of recombinant human keratinocyte growth factor on radiation-induced pulmonary toxicity in rats. Int. J. Radiat. Oncol. Biol. Phys. 60, 1520-1529 (2004). (Pubitemid 39601870)
-
(2004)
International Journal of Radiation Oncology Biology Physics
, vol.60
, Issue.5
, pp. 1520-1529
-
-
Chen, L.1
Brizel, D.M.2
Rabbani, Z.N.3
Samulski, T.V.4
Farrell, C.L.5
Larrier, N.6
Anscher, M.S.7
Vujaskovic, Z.8
-
129
-
-
10344242939
-
Palifermin for oral mucositis after intensive therapy for hematologic cancers
-
DOI 10.1056/NEJMoa040125
-
Spielberger, R. et al. Palifermin for oral mucositis after intensive therapy for hematologic cancers. N.-Engl. J.-Med. 351, 2590-2598 (2004). (Pubitemid 39628580)
-
(2004)
New England Journal of Medicine
, vol.351
, Issue.25
, pp. 2590-2598
-
-
Spielberger, R.1
Stiff, P.2
Bensinger, W.3
Gentile, T.4
Weisdorf, D.5
Kewalramani, T.6
Shea, T.7
Yanovich, S.8
Hansen, K.9
Noga, S.10
McCarty, J.11
LeMaistre, F.12
Sung, E.C.13
Blazar, B.R.14
Elhardt, D.15
Chen, M.-G.16
Emmanouilides, C.17
-
130
-
-
33748670457
-
The pathological response to DNA damage does not contribute to p53-mediated tumour suppression
-
DOI 10.1038/nature05077, PII NATURE05077
-
Christophorou, M. A., Ringshausen, I., Finch, A. J., Swigart, L. B. & Evan, G. I. The pathological response to DNA damage does not contribute to p53-mediated tumour suppression. Nature 443, 214-217 (2006). (Pubitemid 44387609)
-
(2006)
Nature
, vol.443
, Issue.7108
, pp. 214-217
-
-
Christophorou, M.A.1
Ringshausen, I.2
Finch, A.J.3
Swigart, L.B.4
Evan, G.I.5
-
131
-
-
0033543728
-
A chemical inhibitor of p53 that protects mice from the side effects of cancer therapy
-
DOI 10.1126/science.285.5434.1733
-
Komarov, P. G. et al. A chemical inhibitor of p53 that protects mice from the side effects of cancer therapy. Science 285, 1733-1737 (1999). (Pubitemid 29428873)
-
(1999)
Science
, vol.285
, Issue.5434
, pp. 1733-1737
-
-
Komarov, P.G.1
Komarova, E.A.2
Kondratov, R.V.3
Christov-Tselkov, K.4
Coon, J.S.5
Chernov, M.V.6
Gudkov, A.V.7
-
132
-
-
42049095095
-
An agonist of toll-like receptor 5 has radioprotective activity in mouse and primate models
-
DOI 10.1126/science.1154986
-
Burdelya, L. G. et al. An agonist of toll-like receptor 5 has radioprotective activity in mouse and primate models. Science 320, 226-230 (2008). (Pubitemid 351521417)
-
(2008)
Science
, vol.320
, Issue.5873
, pp. 226-230
-
-
Burdelya, L.G.1
Krivokrysenko, V.I.2
Tallant, T.C.3
Strom, E.4
Gleiberman, A.S.5
Gupta, D.6
Kurnasov, O.V.7
Fort, F.L.8
Osterman, A.L.9
DiDonato, J.A.10
Feinstein, E.11
Gudkov, A.V.12
-
133
-
-
0031821938
-
In vivo radioprotective effects of angiogenic growth factors on the small bowel of C3H mice
-
DOI 10.2307/3579856
-
Okunieff, P. et al. In vivo radioprotective effects of angiogenic growth factors on the small bowel of C3H mice. Radiat. Res. 150, 204-211 (1998). (Pubitemid 28347981)
-
(1998)
Radiation Research
, vol.150
, Issue.2
, pp. 204-211
-
-
Okunieff, P.1
Mester, M.2
Wang, J.3
Maddox, T.4
Gong, X.5
Tang, D.6
Coffee, M.7
Ding, I.8
-
134
-
-
0035854479
-
Endothelial apoptosis as the primary lesion initiating intestinal radiation damage in mice
-
DOI 10.1126/science.1060191
-
Paris, F. et al. Endothelial apoptosis as the primary lesion initiating intestinal radiation damage in mice. Science 293, 293-297 (2001). (Pubitemid 32694744)
-
(2001)
Science
, vol.293
, Issue.5528
, pp. 293-297
-
-
Paris, F.1
Fuks, Z.2
Kang, A.3
Capodieci, P.4
Juan, G.5
Ehleiter, D.6
Haimovitz-Friedman, A.7
Cordon-Cardo, C.8
Kolesnick, R.9
-
135
-
-
0028238298
-
Basic fibroblast growth factor protects endothelial cells against radiation-induced programmed cell death in vitro and in vivo
-
Fuks, Z. et al. Basic fibroblast growth factor protects endothelial cells against radiation-induced programmed cell death in vitro and in vivo. Cancer Res. 54, 2582-2590 (1994). (Pubitemid 24173742)
-
(1994)
Cancer Research
, vol.54
, Issue.10
, pp. 2582-2590
-
-
Fuks, Z.1
Persaud, R.S.2
Alfieri, A.3
McLoughlin, M.4
Ehleiter, D.5
Schwartz, J.L.6
Seddon, A.P.7
Cordon-Cardo, C.8
Haimovitz-Friedman, A.9
-
136
-
-
34247176671
-
No significant endothelial apoptosis in the radiation-induced gastrointestinal syndrome
-
DOI 10.1016/j.ijrobp.2006.12.069, PII S0360301607001174
-
Schuller, B. W. et al. No significant endothelial apoptosis in the radiation-induced gastrointestinal syndrome. Int. J. Radiat. Oncol. Biol. Phys. 68, 205-210 (2007). (Pubitemid 46589862)
-
(2007)
International Journal of Radiation Oncology Biology Physics
, vol.68
, Issue.1
, pp. 205-210
-
-
Schuller, B.W.1
Rogers, A.B.2
Cormier, K.S.3
Riley, K.J.4
Binns, P.J.5
Julius, R.6
Hawthorne, M.F.7
Coderre, J.A.8
-
137
-
-
1642580868
-
Radiation, the Ideal Cytotoxic Agent for Studying the Cell Biology of Tissues such as the Small Intestine
-
DOI 10.1667/RR3104
-
Potten, C. S. Radiation, the ideal cytotoxic agent for studying the cell biology of tissues such as the small intestine. Radiat. Res. 161, 123-136 (2004). (Pubitemid 38129805)
-
(2004)
Radiation Research
, vol.161
, Issue.2
, pp. 123-136
-
-
Potten, C.S.1
-
138
-
-
0028812221
-
Basic fibroblast growth factor does not protect against classical radiation pneumonitis in two strains of mice
-
Tee, P. G. & Travis, E. L. Basic fibroblast growth factor does not protect against classical radiation pneumonitis in two strains of mice. Cancer Res. 55, 298-302 (1995).
-
(1995)
Cancer Res.
, vol.55
, pp. 298-302
-
-
Tee, P.G.1
Travis, E.L.2
-
139
-
-
75749114436
-
P53 Controls radiation-induced gastrointestinal syndrome in mice independent of apoptosis
-
Kirsch, D. G. et al. p53 Controls Radiation-Induced Gastrointestinal Syndrome in Mice Independent of Apoptosis. Science 327, 593-596 (2010).
-
(2010)
Science
, vol.327
, pp. 593-596
-
-
Kirsch, D.G.1
-
140
-
-
0042527679
-
Bowel injury: Current and evolving management strategies
-
Hauer-Jensen, M., Wang, J. & Denham, J. W. Bowel injury: current and evolving management strategies. Semin. Radiat. Oncol. 13, 357-371 (2003). (Pubitemid 36962656)
-
(2003)
Seminars in Radiation Oncology
, vol.13
, Issue.3
, pp. 357-371
-
-
Hauer-Jensen, M.1
Wang, J.2
Denham, J.W.3
-
141
-
-
0034178260
-
TGF-β1 and radiation fibrosis: A master switch and a specific therapeutic target?
-
DOI 10.1016/S0360-3016(00)00435-1, PII S0360301600004351
-
Martin, M., Lefaix, J. & Delanian, S. TGF-beta1 and radiation fibrosis: a master switch and a specific therapeutic target? Int. J. Radiat. Oncol. Biol. Phys. 47, 277-290 (2000). (Pubitemid 30236366)
-
(2000)
International Journal of Radiation Oncology Biology Physics
, vol.47
, Issue.2
, pp. 277-290
-
-
Martin, M.1
Lefaix, J.-L.2
Delanian, S.3
-
142
-
-
33747826874
-
Preventing or reducing late side effects of radiation therapy: Radiobiology meets molecular pathology
-
DOI 10.1038/nrc1950, PII NRC1950
-
Bentzen, S. M. Preventing or reducing late side effects of radiation therapy: radiobiology meets molecular pathology. Nature Rev. Cancer 6, 702-713 (2006). (Pubitemid 44286002)
-
(2006)
Nature Reviews Cancer
, vol.6
, Issue.9
, pp. 702-713
-
-
Bentzen, S.M.1
-
143
-
-
0034320191
-
Recombinant soluble transforming growth factor beta type II receptor ameliorates radiation enteropathy in mice
-
Zheng, H., Wang, J., Koteliansky, V. E., Gotwals, P. J. & Hauer-Jensen, M. Recombinant soluble transforming growth factor beta type II receptor ameliorates radiation enteropathy in mice. Gastroenterology 119, 1286-1296 (2000).
-
(2000)
Gastroenterology
, vol.119
, pp. 1286-1296
-
-
Zheng, H.1
Wang, J.2
Koteliansky, V.E.3
Gotwals, P.J.4
Hauer-Jensen, M.5
-
144
-
-
33646919832
-
Antitransforming growth factor-β antibody 1D11 ameliorates normal tissue damage caused by high-dose radiation
-
DOI 10.1016/j.ijrobp.2006.02.051, PII S0360301606003920
-
Anscher, M. S., Thrasher, B., Rabbani, Z., Teicher, B. & Vujaskovic, Z. Antitransforming growth factor-beta antibody 1D11 ameliorates normal tissue damage caused by high-dose radiation. Int. J. Radiat. Oncol. Biol. Phys. 65, 876-881 (2006). (Pubitemid 43795819)
-
(2006)
International Journal of Radiation Oncology Biology Physics
, vol.65
, Issue.3
, pp. 876-881
-
-
Anscher, M.S.1
Thrasher, B.2
Rabbani, Z.3
Teicher, B.4
Vujaskovic, Z.5
-
145
-
-
34848906040
-
Pravastatin inhibits the Rho/CCN2/extracellular matrix cascade in human fibrosis explants and improves radiation-induced intestinal fibrosis in rats
-
DOI 10.1158/1078-0432.CCR-07-0625
-
Haydont, V. et al. Pravastatin Inhibits the Rho/CCN2/extracellular matrix cascade in human fibrosis explants and improves radiation-induced intestinal fibrosis in rats. Clin. Cancer Res. 13, 5331-5340 (2007). (Pubitemid 47510357)
-
(2007)
Clinical Cancer Research
, vol.13
, Issue.18
, pp. 5331-5340
-
-
Haydont, V.1
Bourgier, C.2
Pocard, M.3
Lusinchi, A.4
Aigueperse, J.5
Mathe, D.6
Bourhis, J.7
Vozenin-Brotons, M.-C.8
-
146
-
-
0029073677
-
Amelioration of radiation nephropathy by acetylsalicylic acid
-
Verheij, M., Stewart, F. A., Oussoren, Y., Weening, J. J. & Dewit, L. Amelioration of radiation nephropathy by acetylsalicylic acid. Int. J. Radiat. Biol. 67, 587-596 (1995).
-
(1995)
Int. J. Radiat. Biol.
, vol.67
, pp. 587-596
-
-
Verheij, M.1
Stewart, F.A.2
Oussoren, Y.3
Weening, J.J.4
Dewit, L.5
-
147
-
-
0036149561
-
Short-term inhibition of ADP-induced platelet aggregation by clopidogrel ameliorates radiation-induced toxicity in rat small intestine
-
Wang, J. et al. Short-term inhibition of ADP-induced platelet aggregation by clopidogrel ameliorates radiation-induced toxicity in rat small intestine. Thromb. Haemost. 87, 122-128 (2002). (Pubitemid 34092586)
-
(2002)
Thrombosis and Haemostasis
, vol.87
, Issue.1
, pp. 122-128
-
-
Wang, J.1
Albertson, C.M.2
Zheng, H.3
Fink, L.M.4
Herbert, J.-M.5
Hauer-Jensen, M.6
-
148
-
-
13244299030
-
Hirudin ameliorates intestinal radiation toxicity in the rat: Support for thrombin inhibition as strategy to minimize side-effects after radiation therapy and as countermeasure against radiation exposure
-
DOI 10.1111/j.1538-7836.2004.00960.x
-
Wang, J. et al. Hirudin ameliorates intestinal radiation toxicity in the rat: support for thrombin inhibition as strategy to minimize side-effects after radiation therapy and as countermeasure against radiation exposure. J.-Thromb. Haemost. 2, 2027-2035 (2004). (Pubitemid 40192757)
-
(2004)
Journal of Thrombosis and Haemostasis
, vol.2
, Issue.11
, pp. 2027-2035
-
-
Wang, J.1
Zheng, H.2
Ou, X.3
Albertson, C.M.4
Fink, L.M.5
Herbert, J.-M.6
Hauer-Jensen, M.7
-
149
-
-
0028100021
-
Treatment of radiation-induced nervous system injury with heparin and warfarin
-
Glantz, M. J. et al. Treatment of radiation-induced nervous system injury with heparin and warfarin. Neurology 44, 2020-2027 (1994). (Pubitemid 24349499)
-
(1994)
Neurology
, vol.44
, Issue.11
, pp. 2020-2027
-
-
Glantz, M.J.1
Burger, P.C.2
Friedman, A.H.3
Radtke, R.A.4
Massey, E.W.5
Schold Jr., S.C.6
-
150
-
-
0346993594
-
Pentoxifylline in prevention of radiation-induced lung toxicity in patients with breast and lung cancer: A double-blind randomized trial
-
DOI 10.1016/S0360-3016(03)01444-5
-
Ozturk, B., Egehan, I., Atavci, S. & Kitapci, M. Pentoxifylline in prevention of radiation-induced lung toxicity in patients with breast and lung cancer: a double-blind randomized trial. Int. J. Radiat. Oncol. Biol. Phys. 58, 213-219 (2004). (Pubitemid 38010355)
-
(2004)
International Journal of Radiation Oncology Biology Physics
, vol.58
, Issue.1
, pp. 213-219
-
-
Ozturk, B.1
Egehan, I.2
Atavci, S.3
Kitapci, M.4
-
152
-
-
33845604482
-
Administration of the peroxisomal proliferator-activated receptor γ agonist pioglitazone during fractionated brain irradiation prevents radiation-induced cognitive impairment
-
DOI 10.1016/j.ijrobp.2006.09.036, PII S0360301606031282
-
Zhao, W. et al. Administration of the peroxisomal proliferator-activated receptor gamma agonist pioglitazone during fractionated brain irradiation prevents radiation-induced cognitive impairment. Int. J. Radiat. Oncol. Biol. Phys. 67, 6-9 (2007). (Pubitemid 44959517)
-
(2007)
International Journal of Radiation Oncology Biology Physics
, vol.67
, Issue.1
, pp. 6-9
-
-
Zhao, W.1
Payne, V.2
Tommasi, E.3
Diz, D.I.4
Hsu, F.-C.5
Robbins, M.E.6
-
153
-
-
3042763035
-
Effect of administration of lovastatin on the development of late pulmonary effects after whole-lung irradiation in a murine model
-
DOI 10.1667/RR3168
-
Williams, J. P. et al. Effect of administration of lovastatin on the development of late pulmonary effects after whole-lung irradiation in a murine model. Radiat. Res. 161, 560-567 (2004). (Pubitemid 40754225)
-
(2004)
Radiation Research
, vol.161
, Issue.5
, pp. 560-567
-
-
Williams, J.P.1
Hernady, E.2
Johnston, C.J.3
Reed, C.M.4
Fenton, B.5
Okunieff, P.6
Finkelstein, J.N.7
-
154
-
-
34547429997
-
Simvastatin Ameliorates Radiation Enteropathy Development After Localized, Fractionated Irradiation by a Protein C-Independent Mechanism
-
DOI 10.1016/j.ijrobp.2007.03.036, PII S0360301607005597
-
Wang, J. et al. Simvastatin ameliorates radiation enteropathy development after localized, fractionated irradiation by a protein C-independent mechanism. Int. J. Radiat. Oncol. Biol. Phys. 68, 1483-1490 (2007). (Pubitemid 47176821)
-
(2007)
International Journal of Radiation Oncology Biology Physics
, vol.68
, Issue.5
, pp. 1483-1490
-
-
Wang, J.1
Boerma, M.2
Fu, Q.3
Kulkarni, A.4
Fink, L.M.5
Hauer-Jensen, M.6
-
155
-
-
55049088301
-
Calcium channel blockers may radionsensitize patients to radiation proctitis while statins
-
NSAIDs may radioprotect: a case-control study
-
Irwin, B. C. et al. Calcium channel blockers may radionsensitize patients to radiation proctitis while statins, NSAIDs may radioprotect: a case-control study. Gastroenterology Abstr. 130 (Suppl. 2), A-460 (2006).
-
(2006)
Gastroenterology Abstr.
, vol.130
, Issue.SUPPL. 2
-
-
Irwin, B.C.1
-
156
-
-
34248381622
-
Treatment of radiation nephropathy with ACE inhibitors and AII Type-1 and Type-2 receptor antagonists
-
DOI 10.2174/138161207780618821
-
Moulder, J. E., Fish., B. L. & Cohen, E. P. Treatment of radiation nephropathy with ACE inhibitors and AII type-1 and type-2 receptor antagonists. Curr. Pharm. Des 13, 1317-1325 (2007). (Pubitemid 46746369)
-
(2007)
Current Pharmaceutical Design
, vol.13
, Issue.13
, pp. 1317-1325
-
-
Moulder, J.E.1
Fish, B.L.2
Cohen, E.P.3
-
157
-
-
29244450469
-
Pathogenic role of the renin-angiotensin system in modulating radiation-induced late effects
-
DOI 10.1016/j.ijrobp.2005.08.033, PII S0360301605025782
-
Robbins, M. E. & Diz, D. I. Pathogenic role of the renin-angiotensin system in modulating radiation-induced late effects. Int. J. Radiat. Oncol. Biol. Phys. 64, 6-12 (2006). (Pubitemid 41831202)
-
(2006)
International Journal of Radiation Oncology Biology Physics
, vol.64
, Issue.1
, pp. 6-12
-
-
Robbins, M.E.1
Diz, D.I.2
-
158
-
-
1642580869
-
Modification of radiation injury by ramipril, inhibitor of angiotensin-converting enzyme, on optic neuropathy in the rat
-
DOI 10.1667/RR3124
-
Kim, J. H. et al. Modification of radiation injury by ramipril, inhibitor of angiotensin-converting enzyme, on optic neuropathy in the rat. Radiat. Res. 161, 137-142 (2004). (Pubitemid 38129806)
-
(2004)
Radiation Research
, vol.161
, Issue.2
, pp. 137-142
-
-
Kim, J.H.1
Brown, S.L.2
Kolozsvary, A.3
Jenrow, K.A.4
Ryu, S.5
Rosenblum, M.L.6
Carretero, O.A.7
-
159
-
-
40949138809
-
Captopril to mitigate chronic renal failure after hematopoietic stem cell transplantation: A randomized controlled trial
-
DOI 10.1016/j.ijrobp.2007.08.041, PII S0360301607039922
-
Cohen, E. P. et al. Captopril to mitigate chronic renal failure after hematopoietic stem cell transplantation: a randomized controlled trial. Int. J. Radiat. Oncol. Biol. Phys. 70, 1546-1551 (2008). (Pubitemid 351417757)
-
(2008)
International Journal of Radiation Oncology Biology Physics
, vol.70
, Issue.5
, pp. 1546-1551
-
-
Cohen, E.P.1
Irving, A.A.2
Drobyski, W.R.3
Klein, J.P.4
Passweg, J.5
Talano, J.-A.M.6
Juckett, M.B.7
Moulder, J.E.8
-
160
-
-
0342369395
-
Can angiotensin-converting enzyme inhibitors protect against symptomatic radiation pneumonitis?
-
Wang, L. W. et al. Can. angiotensin-converting enzyme inhibitors protect against symptomatic radiation pneumonitis? Radiat. Res. 153, 405-410 (2000). (Pubitemid 30185393)
-
(2000)
Radiation Research
, vol.153
, Issue.4
, pp. 405-410
-
-
Wang, L.W.1
Fu, X.-L.2
Clough, R.3
Sibley, G.4
Fan, M.5
Bentel, G.C.6
Marks, L.B.7
Anscher, M.S.8
-
161
-
-
0142186658
-
Overexpression of extracellular superoxide dismutase protects mice from radiation-induced lung injury
-
DOI 10.1016/S0360-3016(03)01369-5
-
Kang, S. K. et al. Overexpression of extracellular superoxide dismutase protects mice from radiation-induced lung injury. Int. J. Radiat. Oncol. Biol. Phys. 57, 1056-1066 (2003). (Pubitemid 37324124)
-
(2003)
International Journal of Radiation Oncology Biology Physics
, vol.57
, Issue.4
, pp. 1056-1066
-
-
Kang, S.K.1
Rabbani, Z.N.2
Folz, R.J.3
Golson, M.L.4
Huang, H.5
Yu, D.6
Samulski, T.S.7
Dewhirst, M.W.8
Anscher, M.S.9
Vujaskovic, Z.10
-
162
-
-
26844552427
-
Overexpression of extracellular superoxide dismutase reduces acute radiation induced lung toxicity
-
Rabbani, Z. N. et al. Overexpression of extracellular superoxide dismutase reduces acute radiation induced lung toxicity. BMC Cancer 5, 59 (2005).
-
(2005)
BMC Cancer
, vol.5
, pp. 59
-
-
Rabbani, Z.N.1
-
163
-
-
50649102345
-
Radioprotection in vitro and in vivo by minicircle plasmid carrying the human manganese superoxide dismutase transgene
-
Zhang, X. et al. Radioprotection in vitro and in vivo by minicircle plasmid carrying the human manganese superoxide dismutase transgene. Hum. Gene Ther. 19, 820-826 (2008).
-
(2008)
Hum. Gene Ther.
, vol.19
, pp. 820-826
-
-
Zhang, X.1
-
164
-
-
0029996626
-
Successful treatment of radiation-induced fibrosis using Cu/Zn-SOD and Mn-SOD: An experimental study
-
Lefaix, J. L. et al. Successful treatment of radiation-induced fibrosis using Cu/Zn-SOD and Mn-SOD: an experimental study. Int. J. Radiat. Oncol. Biol. Phys. 35, 305-312 (1996).
-
(1996)
Int. J. Radiat. Oncol. Biol. Phys.
, vol.35
, pp. 305-312
-
-
Lefaix, J.L.1
-
165
-
-
0028066981
-
Successful treatment of radiation-induced fibrosis using liposomal Cu/Zn superoxide dismutase: Clinical trial
-
DOI 10.1016/0167-8140(94)90444-8
-
Delanian, S. et al. Successful treatment of radiation-induced fibrosis using liposomal Cu/Zn superoxide dismutase: clinical trial. Radiother. Oncol. 32, 12-20 (1994). (Pubitemid 24246759)
-
(1994)
Radiotherapy and Oncology
, vol.32
, Issue.1
, pp. 12-20
-
-
Delanian, S.1
-
166
-
-
33947577419
-
Current management for late normal tissue injury: Radiation-induced fibrosis and necrosis
-
DOI 10.1016/j.semradonc.2006.11.006, PII S105342960600107X, Late Normal Tissue Injury
-
Delanian, S. & Lefaix, J. L. Current management for late normal tissue injury: radiation-induced fibrosis and necrosis. Semin. Radiat. Oncol. 17, 99-107 (2007). (Pubitemid 46476864)
-
(2007)
Seminars in Radiation Oncology
, vol.17
, Issue.2
, pp. 99-107
-
-
Delanian, S.1
Lefaix, J.-L.2
-
167
-
-
2942713709
-
A small molecular weight catalytic metalloporphyrin antioxidant with superoxide dismutase (SOD) mimetic properties protects lungs from radiation-induced injury
-
DOI 10.1016/S0891-5849(02)00980-2, PII S0891584902009802
-
Vujaskovic, Z. et al. A small molecular weight catalytic metalloporphyrin antioxidant with superoxide dismutase (SOD) mimetic properties protects lungs from radiation-induced injury. Free Radic. Biol. Med. 33, 857-863 (2002). (Pubitemid 35232320)
-
(2002)
Free Radical Biology and Medicine
, vol.33
, Issue.6
, pp. 857-863
-
-
Vujaskovic, Z.1
Batinic-Haberle, I.2
Rabbani, Z.N.3
Feng, Q.-F.4
Kang, S.K.5
Spasojevic, I.6
Samulski, T.V.7
Fridovich, I.8
Dewhirst, M.W.9
Anscher, M.S.10
-
168
-
-
0038352140
-
Randomized, placebo-controlled trial of combined pentoxifylline and tocopherol for regression of superficial radiation-induced fibrosis
-
DOI 10.1200/JCO.2003.06.064
-
Delanian, S., Porcher, R., Balla-Mekias, S. & Lefaix, J. L. Randomized, placebo-controlled trial of combined pentoxifylline and tocopherol for regression of superficial radiation-induced fibrosis. J. Clin. Oncol. 21, 2545-2550 (2003). (Pubitemid 46606336)
-
(2003)
Journal of Clinical Oncology
, vol.21
, Issue.13
, pp. 2545-2550
-
-
Delanian, S.1
Porcher, R.2
Balla-Mekias, S.3
Lefaix, J.-L.4
-
169
-
-
79957578310
-
Complete restoration of refractory mandibular osteoradionecrosis by prolonged treatment with a Pentoxifylline-Tocopherol-Clodronate Combination (PENTOCLO): A Phase II Trial
-
16-Jul (doi: 10.1016/j.ijrobp2010.03.029.)
-
Delanian, S., Chatel, C., Porcher, R., Depondt, J. & Lefaix, J. L. Complete restoration of refractory mandibular osteoradionecrosis by prolonged treatment with a Pentoxifylline-Tocopherol-Clodronate Combination (PENTOCLO): a Phase II Trial. Int. J. Radiat. Oncol. Biol. Phys. 16-Jul 2010 (doi: 10.1016/j.ijrobp.2010.03.0290
-
(2010)
Int. J. Radiat. Oncol. Biol. Phys.
-
-
Delanian, S.1
Chatel, C.2
Porcher, R.3
Depondt, J.4
Lefaix, J.L.5
-
170
-
-
33947374287
-
Endothelial progenitor cells: A promising therapeutic alternative for cardiovascular disease
-
DOI 10.1111/j.1540-8183.2007.00251.x
-
Dong, C. & Goldschmidt-Clermont, P. J. Endothelial progenitor cells: a promising therapeutic alternative for cardiovascular disease. J.-Interv. Cardiol. 20, 93-99 (2007). (Pubitemid 46457444)
-
(2007)
Journal of Interventional Cardiology
, vol.20
, Issue.2
, pp. 93-99
-
-
Dong, C.1
Goldschmidt-Clermont, P.J.2
-
171
-
-
34247857552
-
Biologic properties of endothelial progenitor cells and their potential for cell therapy
-
DOI 10.1016/j.pcad.2007.02.004, PII S0033062007000230
-
Young, P. P., Vaughan, D. E. & Hatzopoulos, A. K. Biologic properties of endothelial progenitor cells and their potential for cell therapy. Prog. Cardiovasc. Dis. 49, 421-429 (2007). (Pubitemid 46693946)
-
(2007)
Progress in Cardiovascular Diseases
, vol.49
, Issue.6
, pp. 421-429
-
-
Young, P.P.1
Vaughan, D.E.2
Hatzopoulos, A.K.3
-
173
-
-
60649106574
-
Stem cell therapy to reduce radiation-induced normal tissue damage
-
Coppes, R. P., van der Goot, A. & Lombaert, I. M. Stem cell therapy to reduce radiation-induced normal tissue damage. Semin. Radiat. Oncol. 19, 112-121 (2009).
-
(2009)
Semin. Radiat. Oncol.
, vol.19
, pp. 112-121
-
-
Coppes, R.P.1
Van Der Goot, A.2
Lombaert, I.-M.3
-
174
-
-
4644229803
-
Bone marrow origin of cells with capacity for homing and differentiation to esophageal squamous epithelium
-
DOI 10.1667/RR3224
-
Epperly, M. W. et al. Bone marrow origin of cells with capacity for homing and differentiation to esophageal squamous epithelium. Radiat. Res. 162, 233-240 (2004). (Pubitemid 39295423)
-
(2004)
Radiation Research
, vol.162
, Issue.3
, pp. 233-240
-
-
Epperly, M.W.1
Guo, H.2
Shen, H.3
Niu, Y.4
Zhang, X.5
Jefferson, M.6
Sikora, C.A.7
Greenberger, J.S.8
-
175
-
-
33645689430
-
Mobilization of bone marrow stem cells by granulocyte colony-stimulating factor ameliorates radiation-induced damage to salivary glands
-
Lombaert, I. M. et al. Mobilization of bone marrow stem cells by granulocyte colony-stimulating factor ameliorates radiation-induced damage to salivary glands. Clin. Cancer Res. 12, 1804-1812 (2006).
-
(2006)
Clin. Cancer Res.
, vol.12
, pp. 1804-1812
-
-
Lombaert, I.M.1
-
176
-
-
59449098254
-
Cytokine treatment improves parenchymal and vascular damage of salivary glands after irradiation
-
Lombaert, I. M. et al. Cytokine treatment improves parenchymal and vascular damage of salivary glands after irradiation. Clin. Cancer Res. 14, 7741-7750 (2008).
-
(2008)
Clin. Cancer Res.
, vol.14
, pp. 7741-7750
-
-
Lombaert, I.M.1
-
177
-
-
33846405634
-
Human mesenchymal stem cells favour healing of the cutaneous radiation syndrome in a xenogenic transplant model
-
DOI 10.1007/s00277-006-0166-5
-
Francois, S. et al. Human mesenchymal stem cells favour healing of the cutaneous radiation syndrome in a xenogenic transplant model. Ann. Hematol. 86, 1-8 (2007). (Pubitemid 46138311)
-
(2007)
Annals of Hematology
, vol.86
, Issue.1
, pp. 1-8
-
-
Francois, S.1
Mouiseddine, M.2
Mathieu, N.3
Semont, A.4
Monti, P.5
Dudoignon, N.6
Sache, A.7
Boutarfa, A.8
Thierry, D.9
Gourmelon, P.10
Chapel, A.11
-
178
-
-
77952243854
-
Mesenchymal stem cells improve small intestinal integrity through regulation of endogenous epithelial cell homeostasis
-
Semont, A. et al. Mesenchymal stem cells improve small intestinal integrity through regulation of endogenous epithelial cell homeostasis. Cell Death Differ. 17, 952-961 (2010).
-
(2010)
Cell Death Differ.
, vol.17
, pp. 952-961
-
-
Semont, A.1
-
179
-
-
35048898697
-
New approach to radiation burn treatment by dosimetry-guided surgery combined with autologous mesenchymal stem cell therapy
-
DOI 10.2217/17460751.2.5.785
-
Lataillade, J. J. et al. New approach to radiation burn treatment by dosimetry-guided surgery combined with autologous mesenchymal stem cell therapy. Regen. Med. 2, 785-794 (2007). (Pubitemid 47554832)
-
(2007)
Regenerative Medicine
, vol.2
, Issue.5
, pp. 785-794
-
-
Lataillade, J.J.1
Doucet, C.2
Bey, E.3
Carsin, H.4
Huet, C.5
Clairand, I.6
Bottollier-Depois, J.F.7
Chapel, A.8
Ernou, I.9
Gourven, M.10
Boutin, L.11
Hayden, A.12
Carcamo, C.13
Buglova, E.14
Joussemet, M.15
De Revel, T.16
Gourmelon, P.17
-
180
-
-
44349145010
-
Rescue of salivary gland function after stem cell transplantation in irradiated glands
-
Lombaert, I. M. et al. Rescue of salivary gland function after stem cell transplantation in irradiated glands. PLoS ONE 3, e2063 (2008).
-
(2008)
PLoS ONE
, vol.3
-
-
Lombaert, I.M.1
-
181
-
-
0034806368
-
Modification of radiation myelopathy by the transplantation of neural stem cells in the rat
-
Rezvani, M. et al. Modification of radiation myelopathy by the transplantation of neural stem cells in the rat. Radiat. Res. 156, 408-412 (2001). (Pubitemid 32904994)
-
(2001)
Radiation Research
, vol.156
, Issue.4
, pp. 408-412
-
-
Rezvani, M.1
Birds, D.A.2
Hodges, H.3
Hopewell, J.W.4
Milledew, K.5
Wilkinson, J.H.6
-
182
-
-
0032053823
-
The unique physiology of solid tumors: Opportunities (and problems) for cancer therapy
-
Brown, J. M. & Giaccia, A. J. The unique physiology of solid tumors: opportunities (and problems) for cancer therapy. Cancer Res. 58, 1408-1416 (1998). (Pubitemid 28193601)
-
(1998)
Cancer Research
, vol.58
, Issue.7
, pp. 1408-1416
-
-
Brown, J.M.1
Giaccia, A.J.2
-
183
-
-
2342471392
-
Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib
-
DOI 10.1056/NEJMoa040938
-
Lynch, T. J. et al. Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib. N.-Engl. J.-Med. 350, 2129-2139 (2004). (Pubitemid 38637993)
-
(2004)
New England Journal of Medicine
, vol.350
, Issue.21
, pp. 2129-2139
-
-
Lynch, T.J.1
Bell, D.W.2
Sordella, R.3
Gurubhagavatula, S.4
Okimoto, R.A.5
Brannigan, B.W.6
Harris, P.L.7
Haserlat, S.M.8
Supko, J.G.9
Haluska, F.G.10
Louis, D.N.11
Christiani, D.C.12
Settleman, J.13
Haber, D.A.14
-
184
-
-
54949085398
-
K-ras mutations and benefit from cetuximab in advanced colorectal cancer
-
Karapetis, C. S. et al. K-ras mutations and benefit from cetuximab in advanced colorectal cancer. N.-Engl. J.-Med. 359, 1757-1765 (2008).
-
(2008)
N.-Engl. J.-Med.
, vol.359
, pp. 1757-1765
-
-
Karapetis, C.S.1
-
185
-
-
60849097255
-
Gene-expression signatures in breast cancer
-
Sotiriou, C. & Pusztai, L. Gene-expression signatures in breast cancer. N.-Engl. J.-Med. 360, 790-800 (2009).
-
(2009)
N.-Engl. J.-Med.
, vol.360
, pp. 790-800
-
-
Sotiriou, C.1
Pusztai, L.2
-
186
-
-
77951115122
-
International network of cancer genome projects
-
International network of cancer genome projects. Nature 464, 993-998 (2010).
-
(2010)
Nature
, vol.464
, pp. 993-998
-
-
-
187
-
-
33745276511
-
Increased expression of pAKT is associated with radiation resistance in cervical cancer
-
Kim, T. J. et al. Increased expression of pAKT is associated with radiation resistance in cervical cancer. Br. J. Cancer. 94, 1678-1682 (2006).
-
(2006)
Br. J. Cancer.
, vol.94
, pp. 1678-1682
-
-
Kim, T.J.1
-
188
-
-
0036304685
-
Local recurrence in head and neck cancer: Relationship to radiation resistance and signal transduction
-
Gupta, A. K. et al. Local recurrence in head and neck cancer: relationship to radiation resistance and signal transduction. Clin. Cancer Res. 8, 885-892 (2002). (Pubitemid 34742122)
-
(2002)
Clinical Cancer Research
, vol.8
, Issue.3
, pp. 885-892
-
-
Gupta, A.K.1
McKenna, W.G.2
Weber, C.N.3
Feldman, M.D.4
Goldsmith, J.D.5
Mick, R.6
Machtay, M.7
Rosenthal, D.I.8
Bakanauskas, V.J.9
Cerniglia, G.J.10
Bernhard, E.J.11
Weber, R.S.12
Muschel, R.J.13
-
189
-
-
69449090092
-
Utility of DNA repair protein foci for the detection of putative BRCA1 pathway defects in breast cancer biopsies
-
Willers, H. et al. Utility of DNA repair protein foci for the detection of putative BRCA1 pathway defects in breast cancer biopsies. Mol. Cancer Res. 7, 1304-1309 (2009).
-
(2009)
Mol. Cancer Res.
, vol.7
, pp. 1304-1309
-
-
Willers, H.1
-
190
-
-
0028000889
-
Radiobiological considerations in the design of clinical trials
-
Bentzen, S. M. Radiobiological considerations in the design of clinical trials. Radiother. Oncol. 32, 1-11 (1994).
-
(1994)
Radiother. Oncol.
, vol.32
, pp. 1-11
-
-
Bentzen, S.-M.1
-
191
-
-
77953576200
-
A new method for synthesizing radiation dose-response data from multiple trials applied to prostate cancer
-
Diez, P., Vogelius, I. S. & Bentzen, S. M. A new method for synthesizing radiation dose-response data from multiple trials applied to prostate cancer. Int. J. Radiat. Oncol. Biol. Phys. 77, 1066-1071 (2010).
-
(2010)
Int. J. Radiat. Oncol. Biol. Phys.
, vol.77
, pp. 1066-1071
-
-
Diez, P.1
Vogelius, I.S.2
Bentzen, S.-M.3
|