Radiosensitization and DNA repair inhibition by the combined use of novel inhibitors of DNA-dependent protein kinase and poly(ADP-ribose) polymerase-1

Cancer Research

Volumn 63, Issue 18, 2003, Pages 6008-6015

  Veuger, Stephany J ^a   Curtin, Nicola J ^a   Richardson, Caroline J ^b   Smith, Graeme C M ^b   Durkacz, Barbara W ^a  

^a NEWCASTLE UNIVERSITY   (United Kingdom)

^b KuDOS Pharmaceuticals   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

1 (4 DIMETHYLAMINOMETHYLPHENYL) 8,9 DIHYDRO 7H 2,7,9A BENZ[CD]AZULEN 6 ONE; 2 (MORPHOLIN 4 YL) BENZO[H]CHOMEN 4 ONE; AG 14361; DNA DEPENDENT PROTEIN KINASE; DOUBLE STRANDED DNA; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE INHIBITOR; NU 7026; PROTEIN KINASE INHIBITOR; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CANCER CHEMOTHERAPY; CELL CYCLE G0 PHASE; CELL KILLING; CONTROLLED STUDY; CORRELATION ANALYSIS; CYTOTOXICITY; DNA REPAIR; DNA STRAND BREAKAGE; DRUG RESISTANCE; ENZYME INHIBITION; HUMAN; HUMAN CELL; IONIZING RADIATION; LETHALITY; PRIORITY JOURNAL; RADIOSENSITIZATION;

AZULENES; BENZODIAZEPINES; CHROMONES; DNA DAMAGE; DNA REPAIR; DNA-ACTIVATED PROTEIN KINASE; DNA-BINDING PROTEINS; ENZYME INHIBITORS; HELA CELLS; HUMANS; MORPHOLINES; NUCLEAR PROTEINS; POLY(ADP-RIBOSE) POLYMERASES; PROTEIN-SERINE-THREONINE KINASES; RADIATION TOLERANCE; RADIATION-SENSITIZING AGENTS;

EID: 0141619287     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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