Hirudin ameliorates intestinal radiation toxicity in the rat: Support for thrombin inhibition as strategy to minimize side-effects after radiation therapy and as countermeasure against radiation exposure

Journal of Thrombosis and Haemostasis

Volumn 2, Issue 11, 2004, Pages 2027-2035

  Wang, J ^a   Zheng, H ^a   Ou, X ^a   Albertson, C M ^a   Fink, L M ^a,b   Herbert, J M ^c   Hauer Jensen, Martin ^a,b,d  

^a UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

^b CENTRAL ARKANSAS VETERANS HEALTHCARE SYSTEM   (United States)

^c SANOFI   (France)

^d UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

Author keywords

Endothelium; Intestine; Radiation injuries; Thrombin

Indexed keywords

HIRUDIN; HIRUDIN AMELIORATES; RECOMBINANT HIRUDIN; THROMBIN INHIBITOR; UNCLASSIFIED DRUG;

ANTICOAGULATION; ARTICLE; CONTROLLED STUDY; DRUG EFFICACY; DRUG MECHANISM; DRUG TARGETING; ENDOTHELIUM; ENTEROPATHY; ENZYME ACTIVITY; FIBRIN DEPOSITION; HUMAN; NONHUMAN; PREVALENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RADIATION EXPOSURE; RADIATION INJURY; RAT; SMALL INTESTINE DISEASE; THROMBOSIS; UPREGULATION; X RAY;

ANIMALS; FIBRIN; GAMMA RAYS; HIRUDINS; INTESTINAL DISEASES; INTESTINES; MALE; RADIATION INJURIES; RADIATION TOLERANCE; RADIATION-PROTECTIVE AGENTS; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER; THROMBIN; THROMBOPLASTIN;

EID: 13244299030     PISSN: 15387933     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1538-7836.2004.00960.x     Document Type: Article

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