-
1
-
-
0034176782
-
Exploiting the hypoxic cancer cell: Mechanisms and therapeutic strategies
-
J.M. Brown Exploiting the hypoxic cancer cell: mechanisms and therapeutic strategies Mol Med Today 6 2000 157 162
-
(2000)
Mol Med Today
, vol.6
, pp. 157-162
-
-
Brown, J.M.1
-
2
-
-
0035925098
-
Tumor hypoxia: Definitions and current clinical, biologic, and molecular aspects
-
M. Hockel, and P. Vaupel Tumor hypoxia: Definitions and current clinical, biologic, and molecular aspects J Natl Cancer Inst 93 2001 266 276
-
(2001)
J Natl Cancer Inst
, vol.93
, pp. 266-276
-
-
Hockel, M.1
Vaupel, P.2
-
3
-
-
0015412531
-
The phenomenon of reoxygenation and its implications for fractionated radiotherapy
-
R.F. Kallman The phenomenon of reoxygenation and its implications for fractionated radiotherapy Radiology 105 1972 135 142
-
(1972)
Radiology
, vol.105
, pp. 135-142
-
-
Kallman, R.F.1
-
4
-
-
0022537042
-
Tumor oxygenation and reoxygenation during radiation therapy: Their importance in predicting tumor response
-
R.F. Kallman, and M.J. Dorie Tumor oxygenation and reoxygenation during radiation therapy: their importance in predicting tumor response Int J Radiat Oncol Biol Phys 12 1986 681 685
-
(1986)
Int J Radiat Oncol Biol Phys
, vol.12
, pp. 681-685
-
-
Kallman, R.F.1
Dorie, M.J.2
-
5
-
-
0018760476
-
Evidence for acutely hypoxic cells in mouse tumours, and a possible mechanism of reoxygenation
-
J.M. Brown Evidence for acutely hypoxic cells in mouse tumours, and a possible mechanism of reoxygenation Br J Radiol 52 1979 650 656
-
(1979)
Br J Radiol
, vol.52
, pp. 650-656
-
-
Brown, J.M.1
-
6
-
-
0030022252
-
Tumor oxygenation predicts for the likelihood of distant metastases in human soft tissue sarcoma
-
D.M. Brizel, S.P. Scully, and J.M. Harrelson Tumor oxygenation predicts for the likelihood of distant metastases in human soft tissue sarcoma Cancer Res 56 1996 941 943
-
(1996)
Cancer Res
, vol.56
, pp. 941-943
-
-
Brizel, D.M.1
Scully, S.P.2
Harrelson, J.M.3
-
7
-
-
0029775242
-
Association between tumor hypoxia and malignant progression in advanced cancer of the uterine cervix
-
M. Hockel, K. Schlenger, and B. Aral Association between tumor hypoxia and malignant progression in advanced cancer of the uterine cervix Cancer Res 56 1996 4509 4515
-
(1996)
Cancer Res
, vol.56
, pp. 4509-4515
-
-
Hockel, M.1
Schlenger, K.2
Aral, B.3
-
8
-
-
0032708195
-
Oxygenation of head and neck cancer: Changes during radiotherapy and impact on treatment outcome
-
D.M. Brizel, R.K. Dodge, and R.W. Clough Oxygenation of head and neck cancer: Changes during radiotherapy and impact on treatment outcome Radiother Oncol 53 1999 113 117
-
(1999)
Radiother Oncol
, vol.53
, pp. 113-117
-
-
Brizel, D.M.1
Dodge, R.K.2
Clough, R.W.3
-
9
-
-
0033922706
-
Hypoxia-induced treatment failure in advanced squamous cell carcinoma of the uterine cervix is primarily due to hypoxia-induced radiation resistance rather than hypoxia-induced metastasis
-
E.K. Rofstad, K. Sundfor, and H. Lyng Hypoxia-induced treatment failure in advanced squamous cell carcinoma of the uterine cervix is primarily due to hypoxia-induced radiation resistance rather than hypoxia-induced metastasis Br J Cancer 83 2000 354 359
-
(2000)
Br J Cancer
, vol.83
, pp. 354-359
-
-
Rofstad, E.K.1
Sundfor, K.2
Lyng, H.3
-
10
-
-
0030926491
-
Cells at intermediate oxygen levels can be more important than the "hypoxic fraction" in determining tumor response to fractionated radiotherapy
-
B.G. Wouters, and J.M. Brown Cells at intermediate oxygen levels can be more important than the "hypoxic fraction" in determining tumor response to fractionated radiotherapy Radiat Res 147 1997 541 550
-
(1997)
Radiat Res
, vol.147
, pp. 541-550
-
-
Wouters, B.G.1
Brown, J.M.2
-
11
-
-
33847646451
-
Results of a phase i dose-escalation study using single-fraction stereotactic radiotherapy for lung tumors
-
Q.-T. Le, B.W. Loo, and A. Ho Results of a phase I dose-escalation study using single-fraction stereotactic radiotherapy for lung tumors J Thorac Oncol 1 2006 802 809
-
(2006)
J Thorac Oncol
, vol.1
, pp. 802-809
-
-
Le, Q.-T.1
Loo, B.W.2
Ho, A.3
-
12
-
-
77953333694
-
Tumor size is a critical determinant of local control in single fraction stereotactic radiotherapy of pulmonary tumors
-
B.W. Loo, J. Shen, and S. Quinlan-Davidson Tumor size is a critical determinant of local control in single fraction stereotactic radiotherapy of pulmonary tumors Int J Radiat Oncol Biol Phys 72 2008 S467 S468
-
(2008)
Int J Radiat Oncol Biol Phys
, vol.72
-
-
Loo, B.W.1
Shen, J.2
Quinlan-Davidson, S.3
-
13
-
-
54049131325
-
Stereotactic body radiation therapy in centrally and superiorly located stage i or isolated recurrent non-small-cell lung cancer
-
J.Y. Chang, P.A. Balter, and L. Dong Stereotactic body radiation therapy in centrally and superiorly located stage I or isolated recurrent non-small-cell lung cancer Int J Radiat Oncol Biol Phys 72 2008 967 971
-
(2008)
Int J Radiat Oncol Biol Phys
, vol.72
, pp. 967-971
-
-
Chang, J.Y.1
Balter, P.A.2
Dong, L.3
-
14
-
-
68049136288
-
Stereotactic body radiation therapy for early-stage non-small-cell lung carcinoma: Four-year results of a prospective phase II study
-
A.J. Fakiris, R.C. McGarry, and C.T. Yiannoutsos Stereotactic body radiation therapy for early-stage non-small-cell lung carcinoma: Four-year results of a prospective phase II study Int J Radiat Oncol Biol Phys 75 2009 677 682
-
(2009)
Int J Radiat Oncol Biol Phys
, vol.75
, pp. 677-682
-
-
Fakiris, A.J.1
McGarry, R.C.2
Yiannoutsos, C.T.3
-
15
-
-
38849205524
-
Universal survival curve and single fraction equivalent dose: Useful tools in understanding potency of ablative radiotherapy
-
C. Park, L. Papiez, and S. Zhang Universal survival curve and single fraction equivalent dose: Useful tools in understanding potency of ablative radiotherapy Int J Radiat Oncol Biol Phys 70 2008 847 852
-
(2008)
Int J Radiat Oncol Biol Phys
, vol.70
, pp. 847-852
-
-
Park, C.1
Papiez, L.2
Zhang, S.3
-
16
-
-
77949484687
-
Adjuvant whole brain radiotherapy vs. observation after radiosurgery or surgical resection of 1-3 cerebral metastases: Results of the EORTC 22952-26001 study
-
M. Kocher, R.P. Mueller, and M.U. Abacioglu Adjuvant whole brain radiotherapy vs. observation after radiosurgery or surgical resection of 1-3 cerebral metastases: Results of the EORTC 22952-26001 study Int J Radiat Oncol Biol Phys 75 2009 S5
-
(2009)
Int J Radiat Oncol Biol Phys
, vol.75
, pp. 5
-
-
Kocher, M.1
Mueller, R.P.2
Abacioglu, M.U.3
-
17
-
-
27144516385
-
Dose-response in stereotactic irradiation of lung tumors
-
J. Wulf, K. Baier, and G. Mueller Dose-response in stereotactic irradiation of lung tumors Radiother Oncol 77 2005 83 87
-
(2005)
Radiother Oncol
, vol.77
, pp. 83-87
-
-
Wulf, J.1
Baier, K.2
Mueller, G.3
-
18
-
-
34547510573
-
Hypofractionated stereotactic radiotherapy (HypoFXSRT) for stage i non-small cell lung cancer: Updated results of 257 patients in a Japanese multi-institutional study
-
H. Onishi, H. Shirato, and Y. Nagata Hypofractionated stereotactic radiotherapy (HypoFXSRT) for stage I non-small cell lung cancer: Updated results of 257 patients in a Japanese multi-institutional study J Thorac Oncol 2 2007 S94 S100
-
(2007)
J Thorac Oncol
, vol.2
-
-
Onishi, H.1
Shirato, H.2
Nagata, Y.3
-
19
-
-
34547508285
-
The North American experience with stereotactic body radiation therapy in non-small cell lung cancer
-
R.D. Timmerman, C. Park, and B.D. Kavanagh The North American experience with stereotactic body radiation therapy in non-small cell lung cancer J Thorac Oncol 2 2007 S101 S112
-
(2007)
J Thorac Oncol
, vol.2
-
-
Timmerman, R.D.1
Park, C.2
Kavanagh, B.D.3
-
20
-
-
57649100364
-
Observation of a dose-control relationship for lung and liver tumors after stereotactic body radiation therapy
-
R. McCammon, T.E. Schefter, and L.E. Gaspar Observation of a dose-control relationship for lung and liver tumors after stereotactic body radiation therapy Int J Radiat Oncol Biol Phys 73 2009 112 118
-
(2009)
Int J Radiat Oncol Biol Phys
, vol.73
, pp. 112-118
-
-
McCammon, R.1
Schefter, T.E.2
Gaspar, L.E.3
-
21
-
-
34250888085
-
Stereotactic single-dose radiotherapy (radiosurgery) of early stage nonsmall-cell lung cancer (NSCLC)
-
H. Hof, M. Muenter, and D. Oetzel Stereotactic single-dose radiotherapy (radiosurgery) of early stage nonsmall-cell lung cancer (NSCLC) Cancer 110 2007 148 155
-
(2007)
Cancer
, vol.110
, pp. 148-155
-
-
Hof, H.1
Muenter, M.2
Oetzel, D.3
-
22
-
-
0002377529
-
Oxygenation status of human tumors: A reappraisal using computerized pO2 histography
-
P.W. Vaupel, and M. Hockel Oxygenation status of human tumors: A reappraisal using computerized pO2 histography P.W. Vaupel, D.K. Kelleher, M. Gunderoth, Tumor oxygenation 1995 Gustav Fischer Verlag Stuttgart 219 232
-
(1995)
Tumor Oxygenation
, pp. 219-232
-
-
Vaupel, P.W.1
Hockel, M.2
-
23
-
-
0033405294
-
The hypoxic cell: A target for selective cancer therapy-eighteenth Bruce F. Cain Memorial Award lecture
-
J.M. Brown The hypoxic cell: A target for selective cancer therapy-eighteenth Bruce F. Cain Memorial Award lecture Cancer Res 59 1999 5863 5870
-
(1999)
Cancer Res
, vol.59
, pp. 5863-5870
-
-
Brown, J.M.1
-
24
-
-
33645079888
-
An evaluation of tumor oxygenation and gene expression in patients with early stage non-small cell lung cancers
-
Q.-T. Le, E. Chen, and A. Salim An evaluation of tumor oxygenation and gene expression in patients with early stage non-small cell lung cancers Clin Cancer Res 12 2006 1507 1514
-
(2006)
Clin Cancer Res
, vol.12
, pp. 1507-1514
-
-
Le, Q.-T.1
Chen, E.2
Salim, A.3
-
25
-
-
0035341568
-
Relationship between pattern of enhancement and local control of brain metastases after radiosurgery
-
K.A. Goodman, P.K. Sneed, and M.W. McDermott Relationship between pattern of enhancement and local control of brain metastases after radiosurgery Int J Radiat Oncol Biol Phys 50 2001 139 146
-
(2001)
Int J Radiat Oncol Biol Phys
, vol.50
, pp. 139-146
-
-
Goodman, K.A.1
Sneed, P.K.2
McDermott, M.W.3
-
26
-
-
60049088476
-
Stereotactic radiotherapy for unresectable adenocarcinoma of the pancreas
-
D.T. Chang, D. Schellenberg, and J. Shen Stereotactic radiotherapy for unresectable adenocarcinoma of the pancreas Cancer 115 2009 665 672
-
(2009)
Cancer
, vol.115
, pp. 665-672
-
-
Chang, D.T.1
Schellenberg, D.2
Shen, J.3
-
27
-
-
43049152789
-
High-dose, single-fraction image-guided intensity-modulated radiotherapy for metastatic spinal lesions
-
Y. Yamada, M.H. Bilsky, and D.M. Lovelock High-dose, single-fraction image-guided intensity-modulated radiotherapy for metastatic spinal lesions Int J Radiat Oncol Biol Phys 71 2008 484 490
-
(2008)
Int J Radiat Oncol Biol Phys
, vol.71
, pp. 484-490
-
-
Yamada, Y.1
Bilsky, M.H.2
Lovelock, D.M.3
-
28
-
-
70349479538
-
Highly tumorigenic lung cancer CD133+ cells display stem-like features and are spared by cisplatin treatment
-
G. Bertolini, L. Roz, and P. Perego Highly tumorigenic lung cancer CD133+ cells display stem-like features and are spared by cisplatin treatment Proc Natl Acad Sci U S A 106 2009 16281 16286
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 16281-16286
-
-
Bertolini, G.1
Roz, L.2
Perego, P.3
-
29
-
-
0038626211
-
Tumor response to radiotherapy regulated by endothelial cell apoptosis
-
M. Garcia-Barros, F. Paris, and C. Cordon-Cardo Tumor response to radiotherapy regulated by endothelial cell apoptosis Science 300 2003 1155 1159
-
(2003)
Science
, vol.300
, pp. 1155-1159
-
-
Garcia-Barros, M.1
Paris, F.2
Cordon-Cardo, C.3
-
30
-
-
33750612133
-
Excessive toxicity when treating central tumors in a phase II study of stereotactic body radiation therapy for medically inoperable early-stage lung cancer
-
R. Timmerman, R. McGarry, and C. Yiannoutsos Excessive toxicity when treating central tumors in a phase II study of stereotactic body radiation therapy for medically inoperable early-stage lung cancer J Clin Oncol 24 2006 4833 4839
-
(2006)
J Clin Oncol
, vol.24
, pp. 4833-4839
-
-
Timmerman, R.1
McGarry, R.2
Yiannoutsos, C.3
-
31
-
-
70350599744
-
Brachial plexopathy from stereotactic body radiotherapy in early-stage NSCLC: Dose-limiting toxicity in apical tumor sites
-
J.A. Forquer, A.J. Fakiris, and R.D. Timmerman Brachial plexopathy from stereotactic body radiotherapy in early-stage NSCLC: Dose-limiting toxicity in apical tumor sites Radiother Oncol 93 2009 408 413
-
(2009)
Radiother Oncol
, vol.93
, pp. 408-413
-
-
Forquer, J.A.1
Fakiris, A.J.2
Timmerman, R.D.3
-
32
-
-
65649107349
-
Radiation-induced rib fractures after hypofractionated stereotactic body radiation therapy of non-small cell lung cancer: A dose- and volume-response analysis
-
N. Pettersson, J. Nyman, and K.A. Johansson Radiation-induced rib fractures after hypofractionated stereotactic body radiation therapy of non-small cell lung cancer: A dose- and volume-response analysis Radiother Oncol 91 2009 360 368
-
(2009)
Radiother Oncol
, vol.91
, pp. 360-368
-
-
Pettersson, N.1
Nyman, J.2
Johansson, K.A.3
-
33
-
-
76049089527
-
Chest wall volume receiving >30 Gy predicts risk of severe pain and/or rib fracture after lung stereotactic body radiotherapy
-
N.E. Dunlap, J. Cai, and G.B. Biedermann Chest wall volume receiving >30 Gy predicts risk of severe pain and/or rib fracture after lung stereotactic body radiotherapy Int J Radiat Oncol Biol Phys 76 2009 796 801
-
(2009)
Int J Radiat Oncol Biol Phys
, vol.76
, pp. 796-801
-
-
Dunlap, N.E.1
Cai, J.2
Biedermann, G.B.3
-
34
-
-
56349111938
-
Acute skin toxicity following stereotactic body radiation therapy for stage i non-small-cell lung cancer: Who's at risk?
-
B.S. Hoppe, B. Laser, and A.V. Kowalski Acute skin toxicity following stereotactic body radiation therapy for stage I non-small-cell lung cancer: Who's at risk? Int J Radiat Oncol Biol Phys 72 2008 1283 1286
-
(2008)
Int J Radiat Oncol Biol Phys
, vol.72
, pp. 1283-1286
-
-
Hoppe, B.S.1
Laser, B.2
Kowalski, A.V.3
-
35
-
-
0017124222
-
Optimum fractionation of the C3H mouse mammary carcinoma using x-rays, the hypoxic-cell radiosensitizer Ro-07-0582, or fast neutrons
-
J.F. Fowler, P.W. Sheldon, and J. Denekamp Optimum fractionation of the C3H mouse mammary carcinoma using x-rays, the hypoxic-cell radiosensitizer Ro-07-0582, or fast neutrons Int J Radiat Oncol Biol Phys 1 1976 579 592
-
(1976)
Int J Radiat Oncol Biol Phys
, vol.1
, pp. 579-592
-
-
Fowler, J.F.1
Sheldon, P.W.2
Denekamp, J.3
-
36
-
-
0021236301
-
Clinical trials of radiosensitizers: What should we expect?
-
J.M. Brown Clinical trials of radiosensitizers: What should we expect? Int J Radiat Oncol Biol Phys 10 1984 425 429
-
(1984)
Int J Radiat Oncol Biol Phys
, vol.10
, pp. 425-429
-
-
Brown, J.M.1
-
37
-
-
0028176906
-
RTOG #89-06: A phase i study to evaluate intraoperative radiation therapy and the hypoxic cell sensitizer etanidazole in locally advanced malignancies
-
F.E. Halberg, D. Cosmatis, and L.L. Gunderson RTOG #89-06: A phase I study to evaluate intraoperative radiation therapy and the hypoxic cell sensitizer etanidazole in locally advanced malignancies Int J Radiat Oncol Biol Phys 28 1994 201 206
-
(1994)
Int J Radiat Oncol Biol Phys
, vol.28
, pp. 201-206
-
-
Halberg, F.E.1
Cosmatis, D.2
Gunderson, L.L.3
-
38
-
-
0018895221
-
Interaction of misonidazole and oxygen in the radiosensitization of mammalian cells
-
C.C. Ling, H.B. Michaels, and E.R. Epp Interaction of misonidazole and oxygen in the radiosensitization of mammalian cells Int J Radiat Oncol Biol Phys 6 1980 583 589
-
(1980)
Int J Radiat Oncol Biol Phys
, vol.6
, pp. 583-589
-
-
Ling, C.C.1
Michaels, H.B.2
Epp, E.R.3
-
39
-
-
0023910003
-
Misonidazole in fractionated radiotherapy of a murine mammary carcinoma: Comparison of tumor and normal tissue response
-
H.B. Stone Misonidazole in fractionated radiotherapy of a murine mammary carcinoma: Comparison of tumor and normal tissue response Int J Radiat Oncol Biol Phys 14 1988 957 962
-
(1988)
Int J Radiat Oncol Biol Phys
, vol.14
, pp. 957-962
-
-
Stone, H.B.1
-
40
-
-
0030069889
-
Modification of hypoxia-induced radioresistance in tumors by the use of oxygen and sensitizers
-
J. Overgaard, and M.R. Horsman Modification of hypoxia-induced radioresistance in tumors by the use of oxygen and sensitizers Semin Radiat Oncol 6 1996 10 21
-
(1996)
Semin Radiat Oncol
, vol.6
, pp. 10-21
-
-
Overgaard, J.1
Horsman, M.R.2
-
41
-
-
41849142252
-
A phase I-B trial of the radiosensitizer: Etanidazole (SR-2508) with radiosurgery for the treatment of recurrent previously irradiated primary brain tumors or brain metastases (RTOG study 95-02)
-
R.E. Drzymala, T.H. Wasserman, and M. Won A phase I-B trial of the radiosensitizer: Etanidazole (SR-2508) with radiosurgery for the treatment of recurrent previously irradiated primary brain tumors or brain metastases (RTOG study 95-02) Radiother Oncol 87 2008 89 92
-
(2008)
Radiother Oncol
, vol.87
, pp. 89-92
-
-
Drzymala, R.E.1
Wasserman, T.H.2
Won, M.3
-
42
-
-
46549089743
-
Efficacy of novel hypoxic cell sensitiser doranidazole in the treatment of locally advanced pancreatic cancer: Long-term results of a placebo-controlled randomised study
-
K. Karasawa, M. Sunamura, and A. Okamoto Efficacy of novel hypoxic cell sensitiser doranidazole in the treatment of locally advanced pancreatic cancer: Long-term results of a placebo-controlled randomised study Radiother Oncol 87 2008 326 330
-
(2008)
Radiother Oncol
, vol.87
, pp. 326-330
-
-
Karasawa, K.1
Sunamura, M.2
Okamoto, A.3
-
43
-
-
0017117480
-
Radiation and high-dose metronidazole in supratentorial glioblastomas
-
R. Urtasun, P. Band, and J.D. Chapman Radiation and high-dose metronidazole in supratentorial glioblastomas N Engl J Med 294 1976 1364 1367
-
(1976)
N Engl J Med
, vol.294
, pp. 1364-1367
-
-
Urtasun, R.1
Band, P.2
Chapman, J.D.3
-
44
-
-
0019976883
-
Radiation and nitroimidazoles in supratentorial high grade gliomas: A second clinical trial
-
R. Urtasun, M.L. Feldstein, and J. Partington Radiation and nitroimidazoles in supratentorial high grade gliomas: a second clinical trial Br J Cancer 46 1982 101 108
-
(1982)
Br J Cancer
, vol.46
, pp. 101-108
-
-
Urtasun, R.1
Feldstein, M.L.2
Partington, J.3
|