메뉴 건너뛰기




Volumn 162, Issue 6, 2004, Pages 623-634

Enhancement of radiation cytotoxicity by UCN-01 in non-small cell lung carcinoma cells

Author keywords

[No Author keywords available]

Indexed keywords

7 HYDROXYSTAUROSPORINE; PROTEIN P53; SMALL INTERFERING RNA;

EID: 9244260517     PISSN: 00337587     EISSN: None     Source Type: Journal    
DOI: 10.1667/RR3253     Document Type: Article
Times cited : (15)

References (54)
  • 2
    • 0036337742 scopus 로고    scopus 로고
    • Current and future therapeutic approaches in locally advanced (stage III) non-small cell lung cancer
    • A. Davies, D. R. Gandara, P. Lara, Z. Goldberg, P. Roberts and D. Lau, Current and future therapeutic approaches in locally advanced (stage III) non-small cell lung cancer. Semin. Oncol. 29, 10-16 (2002).
    • (2002) Semin. Oncol. , vol.29 , pp. 10-16
    • Davies, A.1    Gandara, D.R.2    Lara, P.3    Goldberg, Z.4    Roberts, P.5    Lau, D.6
  • 3
    • 0037317521 scopus 로고    scopus 로고
    • The role of p53 in determining sensitivity to radiotherapy
    • A. V. Gudkov and E. A. Komarova, The role of p53 in determining sensitivity to radiotherapy. Nat. Rev. Cancer 3, 117-129 (2003).
    • (2003) Nat. Rev. Cancer , vol.3 , pp. 117-129
    • Gudkov, A.V.1    Komarova, E.A.2
  • 5
    • 0033533612 scopus 로고    scopus 로고
    • 14-3-3Sigma is required to prevent mitotic catastrophe after DNA damage
    • T. A. Chan, H. Hermeking, C. Lengauer, K. W. Kinzler and B. Vogelstein, 14-3-3Sigma is required to prevent mitotic catastrophe after DNA damage. Nature 401, 616-620 (1999).
    • (1999) Nature , vol.401 , pp. 616-620
    • Chan, T.A.1    Hermeking, H.2    Lengauer, C.3    Kinzler, K.W.4    Vogelstein, B.5
  • 7
    • 0027137816 scopus 로고
    • Mutations of the p53 gene as a predictor of poor prognosis in patients with non-small-cell lung cancer
    • T. Mitsudomi, T. Oyama, T. Kusano, T. Osaki, R. Nakanishi and T. Shirakusa, Mutations of the p53 gene as a predictor of poor prognosis in patients with non-small-cell lung cancer. J. Natl. Cancer Inst. 85, 2018-2023 (1993).
    • (1993) J. Natl. Cancer Inst. , vol.85 , pp. 2018-2023
    • Mitsudomi, T.1    Oyama, T.2    Kusano, T.3    Osaki, T.4    Nakanishi, R.5    Shirakusa, T.6
  • 8
    • 0025246110 scopus 로고
    • Universal control mechanism regulating onset of M-phase
    • P. Nurse, Universal control mechanism regulating onset of M-phase. Nature 344, 503-508 (1990).
    • (1990) Nature , vol.344 , pp. 503-508
    • Nurse, P.1
  • 9
    • 0028880855 scopus 로고
    • Cyclins, cyclin-dependent kinases and cdk inhibitors: Implications in cell cycle control and cancer
    • T. K. MacLachlan, N. Sang and A. Giordano, Cyclins, cyclin-dependent kinases and cdk inhibitors: Implications in cell cycle control and cancer. Crit. Rev. Eukaryot. Gene Expr. 5, 127-156 (1995).
    • (1995) Crit. Rev. Eukaryot. Gene Expr. , vol.5 , pp. 127-156
    • MacLachlan, T.K.1    Sang, N.2    Giordano, A.3
  • 11
    • 0030867582 scopus 로고    scopus 로고
    • Conservation of the Chk1 checkpoint pathway in mammals: Linkage of DNA damage to Cdk regulation through Cdc25
    • Y. Sanchez, C. Wong, R. S. Thoma, R. Richman, Z. Wu, H. Piwnica-Worms and S. J. Elledge, Conservation of the Chk1 checkpoint pathway in mammals: Linkage of DNA damage to Cdk regulation through Cdc25. Science 277, 1497-1501 (1997).
    • (1997) Science , vol.277 , pp. 1497-1501
    • Sanchez, Y.1    Wong, C.2    Thoma, R.S.3    Richman, R.4    Wu, Z.5    Piwnica-Worms, H.6    Elledge, S.J.7
  • 12
    • 0030768948 scopus 로고    scopus 로고
    • Cdc25 mitotic inducer targeted by chk1 DNA damage checkpoint kinase
    • B. Furnari, N. Rhind and P. Russell, Cdc25 mitotic inducer targeted by chk1 DNA damage checkpoint kinase. Science 277, 1495-1497 (1997).
    • (1997) Science , vol.277 , pp. 1495-1497
    • Furnari, B.1    Rhind, N.2    Russell, P.3
  • 13
    • 0032973830 scopus 로고    scopus 로고
    • Basis for the checkpoint signal specificity that regulates Chk1 and Cds1 protein kinases
    • J. M. Brondello, M. N. Boddy, B. Furnari and P. Russell, Basis for the checkpoint signal specificity that regulates Chk1 and Cds1 protein kinases. Mol. Cell Biol. 19, 4262-4269 (1999).
    • (1999) Mol. Cell Biol. , vol.19 , pp. 4262-4269
    • Brondello, J.M.1    Boddy, M.N.2    Furnari, B.3    Russell, P.4
  • 15
    • 0035823105 scopus 로고    scopus 로고
    • 2 checkpoints and enhances apoptotic activity in HEK-293 cells
    • 2 checkpoints and enhances apoptotic activity in HEK-293 cells. FEBS Lett. 505, 7-12 (2001).
    • (2001) FEBS Lett. , vol.505 , pp. 7-12
    • Yu, Q.1    Rose, J.H.2    Zhang, H.3    Pommier, Y.4
  • 19
    • 0026425587 scopus 로고
    • Antitumor activity of UCN-01, a selective inhibitor of protein kinase C, in murine and human tumor models
    • S. Akinaga, K. Gomi, M. Morimoto, T. Tamaoki and M. Okabe, Antitumor activity of UCN-01, a selective inhibitor of protein kinase C, in murine and human tumor models. Cancer Res. 51, 4888-4892 (1991).
    • (1991) Cancer Res. , vol.51 , pp. 4888-4892
    • Akinaga, S.1    Gomi, K.2    Morimoto, M.3    Tamaoki, T.4    Okabe, M.5
  • 20
    • 0036300312 scopus 로고    scopus 로고
    • 7-Hydroxystaurosporine (UCN-01) preferentially sensitizes cells with a disrupted TP53 to gamma radiation in lung cancer cell lines
    • H. H. Xiao, Y. Makeyev, J. Butler, B. Vikram and W. A. Franklin, 7-Hydroxystaurosporine (UCN-01) preferentially sensitizes cells with a disrupted TP53 to gamma radiation in lung cancer cell lines. Radiat. Res. 158, 84-93 (2002).
    • (2002) Radiat. Res. , vol.158 , pp. 84-93
    • Xiao, H.H.1    Makeyev, Y.2    Butler, J.3    Vikram, B.4    Franklin, W.A.5
  • 21
    • 0030679652 scopus 로고    scopus 로고
    • The effect of UCN-01 (7-hydroxystaurosporine), a potent inhibitor of protein kinase C, on fractionated radiotherapy or daily chemotherapy of a murine fibrosarcoma
    • E. Tsuchida and M. Urano, The effect of UCN-01 (7-hydroxystaurosporine), a potent inhibitor of protein kinase C, on fractionated radiotherapy or daily chemotherapy of a murine fibrosarcoma. Int. J. Radiat. Oncol. Biol. Phys. 39, 1153-1161 (1997).
    • (1997) Int. J. Radiat. Oncol. Biol. Phys. , vol.39 , pp. 1153-1161
    • Tsuchida, E.1    Urano, M.2
  • 22
    • 0036675996 scopus 로고    scopus 로고
    • 7-Hydroxystaurosporine (UCN-01) and ionizing radiation combine to inhibit the growth of Bcl-2-overexpressing U937 leukemia cells through a non-apoptotic mechanism
    • L. Cartee, H. Sankala, C. Davis, R. Smith, S. Maggio, P. S. Lin, P. Dent and S. Grant, 7-Hydroxystaurosporine (UCN-01) and ionizing radiation combine to inhibit the growth of Bcl-2-overexpressing U937 leukemia cells through a non-apoptotic mechanism. Int. J. Oncol. 21, 351-359 (2002).
    • (2002) Int. J. Oncol. , vol.21 , pp. 351-359
    • Cartee, L.1    Sankala, H.2    Davis, C.3    Smith, R.4    Maggio, S.5    Lin, P.S.6    Dent, P.7    Grant, S.8
  • 23
    • 0037194414 scopus 로고    scopus 로고
    • 2 checkpoint by the staurosporine derivative UCN-01 is associated with radiosensitisation in a subset of colorectal tumour cell lines
    • 2 checkpoint by the staurosporine derivative UCN-01 is associated with radiosensitisation in a subset of colorectal tumour cell lines. Br. J. Cancer 87, 352-358 (2002).
    • (2002) Br. J. Cancer , vol.87 , pp. 352-358
    • Playle, L.C.1    Hicks, D.J.2    Qualtrough, D.3    Paraskeva, C.4
  • 24
    • 0034655281 scopus 로고    scopus 로고
    • The radiosensitizing agent 7-hydroxystaurosporine (UCN-01) inhibits the DNA damage checkpoint kinase hChk1
    • E. C. Busby, D. F. Leistritz, R. T. Abraham, L. M. Karnitz and J. N. Sarkaria, The radiosensitizing agent 7-hydroxystaurosporine (UCN-01) inhibits the DNA damage checkpoint kinase hChk1. Cancer Res. 60, 2108-2112 (2000).
    • (2000) Cancer Res. , vol.60 , pp. 2108-2112
    • Busby, E.C.1    Leistritz, D.F.2    Abraham, R.T.3    Karnitz, L.M.4    Sarkaria, J.N.5
  • 29
    • 0027232037 scopus 로고
    • Enhancement of antitumor activity of mitomycin C in vitro and in vivo by UCN-01, a selective inhibitor of protein kinase C
    • S. Akinaga, K. Nomura, K. Gomi and M. Okabe, Enhancement of antitumor activity of mitomycin C in vitro and in vivo by UCN-01, a selective inhibitor of protein kinase C. Cancer Chemother. Pharmacol. 32, 183-189 (1993).
    • (1993) Cancer Chemother. Pharmacol. , vol.32 , pp. 183-189
    • Akinaga, S.1    Nomura, K.2    Gomi, K.3    Okabe, M.4
  • 30
    • 0030870632 scopus 로고    scopus 로고
    • Abrogation of an S-phase checkpoint and potentiation of camptothecin cytotoxicity by 7-hydroxystaurosporine (UCN-01) in human cancer cell lines, possibly influenced by p53 function
    • R. G. Shao, C. X. Cao, T. Shimizu, P. M. O'Connor, K. W. Kohn and Y. Pommier, Abrogation of an S-phase checkpoint and potentiation of camptothecin cytotoxicity by 7-hydroxystaurosporine (UCN-01) in human cancer cell lines, possibly influenced by p53 function. Cancer Res. 57, 4029-4035 (1997).
    • (1997) Cancer Res. , vol.57 , pp. 4029-4035
    • Shao, R.G.1    Cao, C.X.2    Shimizu, T.3    O'Connor, P.M.4    Kohn, K.W.5    Pommier, Y.6
  • 32
    • 0030706078 scopus 로고    scopus 로고
    • UCN-01 in ovary cancer cells: Effective as a single agent and in combination with cis-diamminedichloroplatinum(II) independent of p53 status
    • A. Husain, X. J. Yan, N. Resales, C. Aghajanian, G. K. Schwartz and D. R. Spriggs, UCN-01 in ovary cancer cells: Effective as a single agent and in combination with cis-diamminedichloroplatinum(II) independent of p53 status. Clin. Cancer Res. 3, 2089-2097 (1997).
    • (1997) Clin. Cancer Res. , vol.3 , pp. 2089-2097
    • Husain, A.1    Yan, X.J.2    Resales, N.3    Aghajanian, C.4    Schwartz, G.K.5    Spriggs, D.R.6
  • 34
    • 0033635741 scopus 로고    scopus 로고
    • UCN-01 (7-hydroxystaurosporine) enhances 5-fluorouracil cytotoxicity through down-regulation of thymidylate synthetase messenger RNA
    • S. Abe, T. Kubota, Y. Otani, T. Furukawa, M. Watanabe, K. Kumai and M. Kitajima, UCN-01 (7-hydroxystaurosporine) enhances 5-fluorouracil cytotoxicity through down-regulation of thymidylate synthetase messenger RNA. Jpn. J. Cancer Res. 91, 1192-1198 (2000).
    • (2000) Jpn. J. Cancer Res. , vol.91 , pp. 1192-1198
    • Abe, S.1    Kubota, T.2    Otani, Y.3    Furukawa, T.4    Watanabe, M.5    Kumai, K.6    Kitajima, M.7
  • 39
    • 0001934857 scopus 로고    scopus 로고
    • Mitotic death: A mechanism of survival? A review
    • J. Erenpreisa and M. S. Cragg, Mitotic death: A mechanism of survival? A review. Cancer Cell Int. 1, 1 (2001).
    • (2001) Cancer Cell Int. , vol.1 , pp. 1
    • Erenpreisa, J.1    Cragg, M.S.2
  • 40
    • 0034324572 scopus 로고    scopus 로고
    • UCN-01 and camptothecin induce DNA double-strand breaks in p53 mutant tumor cells, but not in normal or p53 negative epithelial cells
    • C. B. Jones, M. K. Clements, A. Redkar and S. S. Daoud, UCN-01 and camptothecin induce DNA double-strand breaks in p53 mutant tumor cells, but not in normal or p53 negative epithelial cells. Int. J. Oncol. 17, 1043-1051 (2000).
    • (2000) Int. J. Oncol. , vol.17 , pp. 1043-1051
    • Jones, C.B.1    Clements, M.K.2    Redkar, A.3    Daoud, S.S.4
  • 41
    • 9244233663 scopus 로고    scopus 로고
    • ISVC. SAS Institute, Cary, NC, 1999
    • ISVC. SAS Institute, Cary, NC, 1999.
  • 44
    • 0030615323 scopus 로고    scopus 로고
    • 1 phase accumulation induced by UCN-01 is associated with dephosphorylation of Rb and CDK2 proteins as well as induction of CDK inhibitor p21/Cip1/WAF1/Sdi1 in p53-mutated human epidermoid carcinoma A431 cells
    • 1 phase accumulation induced by UCN-01 is associated with dephosphorylation of Rb and CDK2 proteins as well as induction of CDK inhibitor p21/Cip1/WAF1/Sdi1 in p53-mutated human epidermoid carcinoma A431 cells. Cancer Res. 57, 1495-1501 (1997).
    • (1997) Cancer Res. , vol.57 , pp. 1495-1501
    • Akiyama, T.1    Yoshida, T.2    Tsujita, T.3    Shimizu, M.4    Mizukami, T.5    Okabe, M.6    Akinaga, S.7
  • 45
    • 0034905291 scopus 로고    scopus 로고
    • UCN-01 suppresses E2F-1 mediated by ubiquitin-proteasome-dependent degradation
    • C. T. Hsueh, Y. C. Wu and G. K. Schwanz, UCN-01 suppresses E2F-1 mediated by ubiquitin-proteasome-dependent degradation. Clin. Cancer Res. 7, 669-674 (2001).
    • (2001) Clin. Cancer Res. , vol.7 , pp. 669-674
    • Hsueh, C.T.1    Wu, Y.C.2    Schwanz, G.K.3
  • 46
    • 0029871688 scopus 로고    scopus 로고
    • UCN-01, 7-hydroxyl-staurosporine, inhibits kinase activity of cyclin-dependent kinases and reduces the phosphorylation of the retinoblastoma susceptibility gene product in A549 human lung cancer cell line
    • K. Kawakami, H. Futami, J. Takahara and K. Yamaguchi, UCN-01, 7-hydroxyl-staurosporine, inhibits kinase activity of cyclin-dependent kinases and reduces the phosphorylation of the retinoblastoma susceptibility gene product in A549 human lung cancer cell line. Biochem. Biophys. Res. Commun. 219, 778-783 (1996).
    • (1996) Biochem. Biophys. Res. Commun. , vol.219 , pp. 778-783
    • Kawakami, K.1    Futami, H.2    Takahara, J.3    Yamaguchi, K.4
  • 47
    • 0027157590 scopus 로고
    • Cell cycle arrest and growth inhibition by the protein kinase antagonist UCN-01 in human breast carcinoma cells
    • C. M. Seynaeve, M. Stetler-Stevenson, S. Sebers, G. Kaur, E. A. Sausville and P. J. Worland, Cell cycle arrest and growth inhibition by the protein kinase antagonist UCN-01 in human breast carcinoma cells. Cancer Res. 53, 2081-2086 (1993).
    • (1993) Cancer Res. , vol.53 , pp. 2081-2086
    • Seynaeve, C.M.1    Stetler-Stevenson, M.2    Sebers, S.3    Kaur, G.4    Sausville, E.A.5    Worland, P.J.6
  • 49
    • 0033568223 scopus 로고    scopus 로고
    • Cell cycle checkpoint abrogator UCN-01 inhibits DNA repair: Association with attenuation of the interaction of XPA and ERCC1 nucleotide excision repair proteins
    • H. Jiang and L. Y. Yang, Cell cycle checkpoint abrogator UCN-01 inhibits DNA repair: Association with attenuation of the interaction of XPA and ERCC1 nucleotide excision repair proteins. Cancer Res. 59, 4529-4534 (1999).
    • (1999) Cancer Res. , vol.59 , pp. 4529-4534
    • Jiang, H.1    Yang, L.Y.2
  • 50
    • 0037034928 scopus 로고    scopus 로고
    • Interference with PDK1-Akt survival signaling pathway by UCN-01 (7-hydroxystaurosporine)
    • S. Sato, N. Fujita and T. Tsuruo, Interference with PDK1-Akt survival signaling pathway by UCN-01 (7-hydroxystaurosporine). Oncogene 21, 1727-1738 (2002).
    • (2002) Oncogene , vol.21 , pp. 1727-1738
    • Sato, S.1    Fujita, N.2    Tsuruo, T.3
  • 53
    • 0034084735 scopus 로고    scopus 로고
    • Physiological modeling of altered pharmacokinetics of a novel anticancer drug, UCN-01 (7-hydroxystaurosporine), caused by slow dissociation of UCN-01 from human alpha1-acid glycoprotein
    • E. Fuse, A. Hashimoto, N. Sato, H. Tanii, T. Kuwabara, S. Kobayashi and Y. Sugiyama, Physiological modeling of altered pharmacokinetics of a novel anticancer drug, UCN-01 (7-hydroxystaurosporine), caused by slow dissociation of UCN-01 from human alpha1-acid . glycoprotein. Pharm. Res. 17, 553-564 (2000).
    • (2000) Pharm. Res. , vol.17 , pp. 553-564
    • Fuse, E.1    Hashimoto, A.2    Sato, N.3    Tanii, H.4    Kuwabara, T.5    Kobayashi, S.6    Sugiyama, Y.7
  • 54
    • 0036057475 scopus 로고    scopus 로고
    • The cell cycle as a target for cancer therapy: Basic and clinical findings with the small molecule inhibitors flavopiridol and UCN-01
    • A. M. Senderowicz, The cell cycle as a target for cancer therapy: Basic and clinical findings with the small molecule inhibitors flavopiridol and UCN-01. Oncologist 7 (Suppl. 2), 12-19 (2002).
    • (2002) Oncologist , vol.7 , Issue.2 SUPPL. , pp. 12-19
    • Senderowicz, A.M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.