Contribution of base lesions to radiation-induced clustered DNA damage: Implication for models of radiation response

Radiation Research

Volumn 156, Issue 5 II, 2001, Pages 590-593

  Jenner, T J ^a   Fulford, J ^a   O'Neill, P ^a  

^a MRC Harwell   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

DNA BASE; PLASMID DNA;

ALPHA RADIATION; BIOPHYSICS; CONFERENCE PAPER; DNA DAMAGE; ENERGY; GAMMA RADIATION; IONIZING RADIATION; MODEL; NONHUMAN; PRIORITY JOURNAL;

EID: 0034753408     PISSN: 00337587     EISSN: None     Source Type: Journal    
DOI: 10.1667/0033-7587(2001)156[0590:cobltr]2.0.co;2     Document Type: Conference Paper

References (26)

1. Effects of radiations of different qualities on cells: Molecular mechanisms of damage and repair
2. DNA damage produced by ionising radiation in mammalian cells: Identities, mechanisms of formation and reparability
3. Primary free radical processes in DNA
4. DNA damage induced in cells by gamma and UVA radiations: Calibrated comet assay, with HPLC/GC-MS and HPLC-EC measurements
5. Misrejoining of DNA double-strand breaks in primary and transformed human and rodent cells: A comparison between the HPRT region and other genomic locations
6. In vitro repair of synthetic ionizing radiation-induced multiply damaged DNA sites
7. The action of Escherichia coli endonuclease III on multiply damaged sites in DNA
8. Clustered DNA damage, influence on damage excision by xrs5 nuclear extracts and Escherichia coli Nth and Fpg proteins
9. Induction and rejoining of DNA double-strand breaks in V79-4 mammalian cells following gamma- and α-irradiation
10. A review of dsb induction data for varying quality radiations
11. Radiation chemical mechanisms of single- and double-strand break formation in irradiated SV40 DNA
12. DNA double strand break repair determines the RBE of alpha particles
13. Biochemistry of DNA lesions
14. The complexity of radiation-induced DNA damage as revealed by exposure to cell extracts
15. The severity of alpha-particle-induced DNA damage is revealed by exposure to cell-free extracts
16. Radiation-chemistry of d(TpApCpG) in oxygenated solution
17. A study of endonuclease III-sensitive sites in irradiated DNA: Detection of αparticle-induced oxidative damage
18. DNA strand-break yields after post-irradiation incubation with base excision repair endonucleases implicate hydroxyl radical pairs in double-strand break formation
19. On the experimental distinction between ssbs and dsbs in circular DNA
20. 4He ions
21. Quantitative modelling of DNA damage using Monte Carlo track structure methods
22. Clustered DNA damages induced in isolated DNA and in human cells by low doses of ionizing radiation
23. Clustered damages and total lesions induced in DNA by ionizing radiation: Oxidised bases and strand breaks
24. Gel electrophoresis method for quantification of gamma ray induced single- and double-strand breaks in DNA irradiated in vitro
25. Radiation-induced heat-labile sites that convert into DNA double-strand breaks