Administration of the peroxisomal proliferator-activated receptor γ agonist pioglitazone during fractionated brain irradiation prevents radiation-induced cognitive impairment

International Journal of Radiation Oncology Biology Physics

Volumn 67, Issue 1, 2007, Pages 6-9

  Zhao, Weiling ^a   Payne, Valerie ^a   Tommasi, Ellen ^a   Diz, Debra I ^a   Hsu, Fang Chi ^a   Robbins, Mike E ^a  

^a WAKE FOREST SCHOOL OF MEDICINE   (United States)

Author keywords

Cognitive impairment; Pioglitazone; PPAR ; Rat brain; Whole brain irradiation

Indexed keywords

BIODIVERSITY; BRAIN; IRRADIATION; NUTRITION; PATIENT TREATMENT; TUMORS;

COGNITIVE IMPAIRMENT; PIOGLITAZONE; PPARΓ; RAT BRAIN; WHOLE BRAIN IRRADIATION;

PROTEINS;

PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA AGONIST; PIOGLITAZONE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN RADIATION; COGNITION; COGNITIVE DEFECT; CONTROLLED STUDY; DRUG TOLERANCE; FISCHER 344 RAT; MALE; NONHUMAN; PRIORITY JOURNAL; QUALITY OF LIFE; RADIATION DOSE FRACTIONATION; RAT; RAT STRAIN; TREATMENT PLANNING; TREATMENT RESPONSE;

ANALYSIS OF VARIANCE; ANIMALS; BODY WEIGHT; BRAIN; COGNITION; COGNITION DISORDERS; CRANIAL IRRADIATION; DRUG ADMINISTRATION SCHEDULE; INSULIN; MALE; PPAR GAMMA; RADIATION DOSAGE; RANDOM ALLOCATION; RATS; RATS, INBRED F344; THIAZOLIDINEDIONES;

EID: 33845604482     PISSN: 03603016     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijrobp.2006.09.036     Document Type: Article

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