Simvastatin Ameliorates Radiation Enteropathy Development After Localized, Fractionated Irradiation by a Protein C-Independent Mechanism

International Journal of Radiation Oncology Biology Physics

Volumn 68, Issue 5, 2007, Pages 1483-1490

  Wang, Junru ^a   Boerma, Marjan ^a   Fu, Qiang ^a   Kulkarni, Ashwini ^a   Fink, Louis M ^c   Hauer Jensen, Martin ^a,b  

^a CENTRAL ARKANSAS VETERANS HEALTHCARE SYSTEM   (United States)

^b UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

^c NEVADA CANCER INSTITUTE   (United States)

Author keywords

Endothelium; Hydroxymethylglutaryl CoA reductase inhibitors; Intestine; Radiation injuries

Indexed keywords

ACTIVATION ANALYSIS; IMMUNOLOGY; PROTEINS; RADIOTHERAPY; TISSUE ENGINEERING;

ENDOTHELIUM; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; INTESTINE; RADIATION INJURIES; RADIATION RESPONSES;

RADIATION EFFECTS;

COLLAGEN TYPE 1; PROTEIN C; SIMVASTATIN; THROMBOMODULIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; HISTOLOGY; IMMUNOHISTOCHEMISTRY; INTESTINE WALL; IRRADIATION; MALE; MORPHOMETRICS; MOUSE; MUCOSA CELL; MUTANT; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PRIORITY JOURNAL; PROTECTION; RADIATION ENTEROPATHY; RADIATION PROTECTION; RAT; REGULATORY MECHANISM; SHAM FEEDING; SMALL INTESTINE; THICKNESS;

ANIMALS; ANTILIPEMIC AGENTS; C-REACTIVE PROTEIN; DRUG EVALUATION, PRECLINICAL; FEMALE; INTESTINE, SMALL; MALE; MICE; RADIATION INJURIES, EXPERIMENTAL; RADIATION-PROTECTIVE AGENTS; RATS; RATS, SPRAGUE-DAWLEY; SIMVASTATIN;

EID: 34547429997     PISSN: 03603016     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijrobp.2007.03.036     Document Type: Article

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