-
1
-
-
0025939587
-
Tolerance of normal tissue to therapeutic irradiation
-
Emami B, Lyman J, Brown A, et al. Tolerance of normal tissue to therapeutic irradiation. Int J Radiat Oncol Biol Phys 1991;21:109-22.
-
(1991)
Int J Radiat Oncol Biol Phys
, vol.21
, pp. 109-122
-
-
Emami, B.1
Lyman, J.2
Brown, A.3
-
2
-
-
0033621687
-
2) is a prognostic factor for local control in head and neck cancers
-
DOI 10.1016/S0360-3016(99)00373-9, PII S0360301699003739
-
Bjork-Eriksson T, West C, Karlsson E, Mercke C. Tumor radiosensitivity (SF2) is a prognostic factor for local control in head and neck cancers. Int J Radiat Oncol Biol Phys 2000;46:13-19 (Pubitemid 30021473)
-
(2000)
International Journal of Radiation Oncology Biology Physics
, vol.46
, Issue.1
, pp. 13-19
-
-
Bjork-Eriksson, T.1
West, C.2
Karlsson, E.3
Mercke, C.4
-
3
-
-
0030766981
-
The independence of intrinsic radiosensitivity as a prognostic factor for patient response to radiotherapy of carcinoma of the cervix
-
West CM, Davidson SE, Roberts SA, Hunter RD. The independence of intrinsic radiosensitivity as a prognostic factor for patient response to radiotherapy of carcinoma of the cervix. Br J Cancer 1997;76: 1184-190.
-
(1997)
Br J Cancer
, vol.76
, pp. 1184-1190
-
-
West, C.M.1
Davidson, S.E.2
Roberts, S.A.3
Hunter, R.D.4
-
4
-
-
0028019862
-
Vitro parameters and treatment outcome in head and neck cancers treated with surgery and/or radiation: Cell characterization and correlations with local control and overall survival
-
Girinsky T, Bernheim A, Lubin R, et al. In vitro parameters and treatment outcome in head and neck cancers treated with surgery and/or radiation: cell characterization and correlations with local control and overall survival. Int J Radiat Oncol Biol Phys 1994;30: 789-794
-
(1994)
Int J Radiat Oncol Biol Phys
, vol.30
, pp. 789-794
-
-
Girinsky, T.1
Bernheim, A.2
Lubin, R.3
-
5
-
-
32144433159
-
Radiotherapy plus cetuximab for squamous-cell carcinoma of the head and neck
-
Bonner JA, Harari PM, Giralt J, et al. Radiotherapy plus cetuximab for squamous-cell carcinoma of the head and neck. N Engl J Med 2006; 354:567-578
-
(2006)
N Engl J Med
, vol.354
, pp. 567-578
-
-
Bonner, J.A.1
Harari, P.M.2
Giralt, J.3
-
6
-
-
54749113690
-
Growth inhibition and radiosensitization of glioblastoma and lung cancer cells by small interfering RNA silencing of tumor necrosis factor receptor-associated factor 2
-
Zheng M, Morgan-Lappe SE, Yang J, et al. Growth inhibition and radiosensitization of glioblastoma and lung cancer cells by small interfering RNA silencing of tumor necrosis factor receptor-associated factor 2. Cancer Res 2008;68:7570-7578
-
(2008)
Cancer Res
, vol.68
, pp. 7570-7578
-
-
Zheng, M.1
Morgan-Lappe, S.E.2
Yang, J.3
-
7
-
-
35649028388
-
A loss of function screen identifies nine new radiation susceptibility genes
-
DOI 10.1016/j.bbrc.2007.10.074, PII S0006291X07022425
-
Sudo H, Tsuji AB, Sugyo A, Imai T, Saga T, Harada YN. A loss of function screen identifies nine new radiation susceptibility genes. Biochem Biophys Res Commun 2007;364:695-701. (Pubitemid 350026518)
-
(2007)
Biochemical and Biophysical Research Communications
, vol.364
, Issue.3
, pp. 695-701
-
-
Sudo, H.1
Tsuji, A.B.2
Sugyo, A.3
Imai, T.4
Saga, T.5
Harada, Y.-N.6
-
8
-
-
34548313955
-
Clonogenic assay of cells in vitro
-
Franken NA, Rodermond HM, Stap J, Haveman J, van Bree C. Clonogenic assay of cells in vitro. Nat Protoc 2006;1:2315-2319
-
(2006)
Nat Protoc
, vol.1
, pp. 2315-2319
-
-
Franken, N.A.1
Rodermond, H.M.2
Stap, J.3
Haveman, J.4
Van Bree, C.5
-
9
-
-
0019439264
-
Effect of dose rate on the induction of DNA double-strand breaks in eukaryotic cells
-
DOI 10.2307/3575532
-
Frankenberg-Schwager M, Frankenberg D, Blocher D, Adamczyk C. Effect of dose rate on the induction of DNA double-strand breaks in eucaryotic cells. Radiat Res 1981;87:710-717 (Pubitemid 11057675)
-
(1981)
Radiation Research
, vol.87
, Issue.3
, pp. 710-717
-
-
Frankenberg-Schwager, M.1
Frankenberg, D.2
Bloecher, D.3
Adamczyk, C.4
-
10
-
-
0025836802
-
Sublethal damage, potentially lethal damage, and chromosomal aberrations in mammalian cells exposed to ionizing radiations
-
Bedford JS. Sublethal damage, potentially lethal damage, and chromosomal aberrations in mammalian cells exposed to ionizing radiations. Int J Radiat Oncol Biol Phys 1991;21:1457-1469
-
(1991)
Int J Radiat Oncol Biol Phys
, vol.21
, pp. 1457-1469
-
-
Bedford, J.S.1
-
11
-
-
4944234150
-
Radiation sensitivity, H2AX phosphorylation, and kinetics of repair of DNA strand breaks in irradiated cervical cancer cell lines
-
Banath JP, Macphail SH, Olive PL. Radiation sensitivity, H2AX phosphorylation, and kinetics of repair of DNA strand breaks in irradiated cervical cancer cell lines. Cancer Res 2004;64:7144-7149
-
(2004)
Cancer Res
, vol.64
, pp. 7144-7149
-
-
Banath, J.P.1
Macphail, S.H.2
Olive, P.L.3
-
12
-
-
0346457085
-
Histone H2AX Phosphorylation as a Predictor of Radiosensitivity and Target for Radiotherapy
-
DOI 10.1074/jbc.M310030200
-
Taneja N, Davis M, Choy JS, et al. Histone H2AX phosphorylation as a predictor of radiosensitivity and target for radiotherapy. J Biol Chem 2004;279:2273-2280 (Pubitemid 38084500)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.3
, pp. 2273-2280
-
-
Taneja, N.1
Davis, M.2
Choy, J.S.3
Beckett, M.A.4
Singh, R.5
Kron, S.J.6
Weichselbaum, R.R.7
-
13
-
-
24744452428
-
Selective inhibition of Ras, phosphoinositide 3 kinase, and Akt isoforms increases the radiosensitivity of human carcinoma cell lines
-
DOI 10.1158/0008-5472.CAN-05-0513
-
Kim IA, Bae SS, Fernandes A, et al. Selective inhibition of Ras, phosphoinositide 3 kinase, and Akt isoforms increases the radiosensitivity of human carcinoma cell lines. Cancer Res 2005;65:7902-7910 (Pubitemid 41297268)
-
(2005)
Cancer Research
, vol.65
, Issue.17
, pp. 7902-7910
-
-
Kim, I.-A.1
Bae, S.-S.2
Fernandes, A.3
Wu, J.4
Muschel, R.J.5
McKenna, W.G.6
Birnbaum, M.J.7
Bernhard, E.J.8
-
14
-
-
0023186270
-
The raf oncogene is associated with a radiation-resistant human laryngeal cancer
-
KasidU,PfeiferA,WeichselbaumRR,DritschiloA,MarkGE. Therafoncogeneisassociatedwitharadiation-resistanthumanlaryngealcancer. Science1987;237:1039-1041(Pubitemid17131202)
-
(1987)
Science
, vol.237
, Issue.4818
, pp. 1039-1041
-
-
Kasid, U.1
Pfeifer, A.2
Weichselbaum, R.R.3
-
15
-
-
48649096069
-
Class i PI3 kinase inhibition by the pyridinylfuranopyrimidine inhibitor PI-103 enhances tumor radiosensitivity
-
Prevo R, Deutsch E, Sampson O, et al. Class I PI3 kinase inhibition by the pyridinylfuranopyrimidine inhibitor PI-103 enhances tumor radiosensitivity. Cancer Res 2008;68:5915-5923
-
(2008)
Cancer Res
, vol.68
, pp. 5915-5923
-
-
Prevo, R.1
Deutsch, E.2
Sampson, O.3
-
17
-
-
0038031592
-
Role of BRCA1 in cellular resistance to paclitaxel and ionizing radiation in an ovarian cancer cell line carrying a defective BRCA1
-
DOI 10.1038/sj.onc.1206319
-
Zhou C, Smith JL, Liu J. Role of BRCA1 in cellular resistance to paclitaxel and ionizing radiation in an ovarian cancer cell line carrying a defective BRCA1. Oncogene 2003;22:2396-2404 (Pubitemid 36560723)
-
(2003)
Oncogene
, vol.22
, Issue.16
, pp. 2396-2404
-
-
Zhou, C.1
Smith, J.L.2
Liu, J.3
-
18
-
-
0032126029
-
Double-strand break repair deficiency and radiation sensitivity in BRCA2 mutant cancer cells
-
Abbott DW, Freeman ML, Holt JT. Double-strand break repair deficiency and radiation sensitivity in BRCA2 mutant cancer cells. J Natl Cancer Inst 1998;90:978-985
-
(1998)
J Natl Cancer Inst
, vol.90
, pp. 978-985
-
-
Abbott, D.W.1
Freeman, M.L.2
Holt, J.T.3
-
19
-
-
67349246802
-
CtIP-BRCA1 modulates the choice of DNA doublestrandbreak repair pathway throughout the cell cycle
-
Yun MH, Hiom K. CtIP-BRCA1 modulates the choice of DNA doublestrandbreak repair pathway throughout the cell cycle. Nature 2009; 459:460-463
-
(2009)
Nature
, vol.459
, pp. 460-463
-
-
Yun, M.H.1
Hiom, K.2
-
20
-
-
0035834067
-
DNA ligase IV-deficient cells are more resistant to ionizing radiation in the absence of Ku70: Implications for DNA double-strand break repair
-
DOI 10.1073/pnas.201271098
-
Adachi N, Ishino T, Ishii Y, Takeda S, Koyama H. DNA ligase IVdeficient cells are more resistant to ionizing radiation in the absence of Ku70: implications for DNA double-strand break repair. Proc Natl Acad Sci U S A 2001;98:12109-12113 (Pubitemid 32959835)
-
(2001)
Proceedings of the National Academy of Sciences of the United States of America
, vol.98
, Issue.21
, pp. 12109-12113
-
-
Adachi, N.1
Ishino, T.2
Ishii, Y.3
Takeda, S.4
Koyama, H.5
-
21
-
-
0028897304
-
DNA-dependent protein kinase activity is absent in xrs-6 cells: Implications for sitespecific recombination and DNA double-strand break repair
-
Finnie NJ, GottliebTM, Blunt T, JeggoPA, JacksonSP.DNA-dependent protein kinase activity is absent in xrs-6 cells: implications for sitespecific recombination and DNA double-strand break repair. Proc Natl Acad Sci U S A 1995;92:320-324
-
(1995)
Proc Natl Acad Sci U S A
, vol.92
, pp. 320-324
-
-
Finnie, N.J.1
Gottlieb, T.M.2
Blunt, T.3
Jeggo, P.A.4
Jackson, S.P.5
-
22
-
-
0033574001
-
Catalytic subunit of DNA-dependent protein kinase: Impact on lymphocyte development and tumorigenesis
-
DOI 10.1073/pnas.96.4.1403
-
Kurimasa A, Ouyang H, Dong LJ, et al. Catalytic subunit of DNAdependent protein kinase: impact on lymphocyte development and tumorigenesis. Proc Natl Acad Sci U S A 1999;96:1403-1408 (Pubitemid 29098463)
-
(1999)
Proceedings of the National Academy of Sciences of the United States of America
, vol.96
, Issue.4
, pp. 1403-1408
-
-
Kurimasa, A.1
Ouyang, H.2
Dong, L.-J.3
Wang, S.4
Li, X.5
Cordon-Cardo, C.6
Chen, D.J.7
Li, G.C.8
-
23
-
-
0037417373
-
Histone deacetylase 4 interacts with 53BP1 to mediate the DNA damage response
-
Kao GD, McKenna WG, Guenther MG, Muschel RJ, Lazar MA, Yen TJ. Histone deacetylase 4 interacts with 53BP1 to mediate the DNA damage response. J Cell Biol 2003;160:1017-1027
-
(2003)
J Cell Biol
, vol.160
, pp. 1017-1027
-
-
Kao, G.D.1
McKenna, W.G.2
Guenther, M.G.3
Muschel, R.J.4
Lazar, Ma.5
Yen, T.J.6
-
24
-
-
33845320139
-
Tipin and Timeless form a mutually protective complex required for genotoxic stress resistance and checkpoint function
-
Chou DM, Elledge SJ. Tipin and Timeless form a mutually protective complex required for genotoxic stress resistance and checkpoint function. Proc Natl Acad Sci U S A 2006;103:18143-18147
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 18143-18147
-
-
Chou, D.M.1
Elledge, S.J.2
-
25
-
-
10744224912
-
DNA polymerase θ is preferentially expressed in lymphoid tissues and upregulated in human cancers
-
DOI 10.1002/ijc.11666
-
Kawamura K, Bahar R, Seimiya M, et al. DNA polymerase A is preferentially expressed in lymphoid tissues and upregulated in human cancers. Int J Cancer 2004;109:9-16. (Pubitemid 38160656)
-
(2004)
International Journal of Cancer
, vol.109
, Issue.1
, pp. 9-16
-
-
Kawamura, K.1
Bahar, R.2
Seimiya, M.3
Chiyo, M.4
Wada, A.5
Okada, S.6
Hatano, M.7
Tokuhisa, T.8
Kimura, H.9
Watanabe, S.10
Honda, I.11
Sakiyama, S.12
Tagawa, M.13
O-Wang, J.14
-
26
-
-
20044366163
-
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma
-
Stupp R, Mason WP, van den Bent MJ, et al. Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma. N Engl J Med 2005;352:987-996
-
(2005)
N Engl J Med
, vol.352
, pp. 987-996
-
-
Stupp, R.1
Mason, W.P.2
Van Den Bent, M.J.3
-
27
-
-
22244448679
-
The role of base excision repair in the sensitivity and resistance to temozolomide-mediated cell death
-
DOI 10.1158/0008-5472.CAN-05-0715
-
Trivedi RN, Almeida KH, Fornsaglio JL, Schamus S, Sobol RW. The role of base excision repair in the sensitivity and resistance to temozolomide-mediated cell death. Cancer Res 2005;65:6394-6400 (Pubitemid 40994427)
-
(2005)
Cancer Research
, vol.65
, Issue.14
, pp. 6394-6400
-
-
Trivedi, R.N.1
Almeida, K.H.2
Fornsaglio, J.L.3
Schamus, S.4
Sobol, R.W.5
-
28
-
-
67651125091
-
Clinical radiation sensitivity with DNA repair disorders: An overview
-
Pollard JM, Gatti RA. Clinical radiation sensitivity with DNA repair disorders: an overview. Int J Radiat Oncol Biol Phys 2009;74: 1323-1331
-
(2009)
Int J Radiat Oncol Biol Phys
, vol.74
, pp. 1323-1331
-
-
Pollard, J.M.1
Gatti, R.A.2
-
29
-
-
45749106028
-
Phase i trial of the human immunodeficiency virus protease inhibitor nelfinavir and chemoradiation for locally advanced pancreatic cancer
-
Brunner TB, Geiger M, Grabenbauer GG, et al. Phase I trial of the human immunodeficiency virus protease inhibitor nelfinavir and chemoradiation for locally advanced pancreatic cancer. J Clin Oncol 2008;26:2699-2706
-
(2008)
J Clin Oncol
, vol.26
, pp. 2699-2706
-
-
Brunner, T.B.1
Geiger, M.2
Grabenbauer, G.G.3
-
30
-
-
26244439873
-
ATM-dependentDNAdamage-independent mitotic phosphorylation of H2AX in normally growing mammalian cells
-
McManus KJ, HendzelMJ. ATM-dependentDNAdamage-independent mitotic phosphorylation of H2AX in normally growing mammalian cells. Mol Biol Cell 2005;16:5013-5025
-
(2005)
Mol Biol Cell
, vol.16
, pp. 5013-5025
-
-
McManus, K.J.1
Hendzel, M.J.2
-
31
-
-
46349087126
-
Low-fidelity DNA synthesis by human DNA polymerase theta
-
DOI 10.1093/nar/gkn310
-
Arana ME, Seki M, Wood RD, Rogozin IB, Kunkel TA. Low-fidelity DNA synthesis by human DNA polymerase A. Nucleic Acids Res 2008;36:3847-3856 (Pubitemid 351917544)
-
(2008)
Nucleic Acids Research
, vol.36
, Issue.11
, pp. 3847-3856
-
-
Arana, M.E.1
Seki, M.2
Wood, R.D.3
Rogozin, I.B.4
Kunkel, T.A.5
-
32
-
-
10044288293
-
High-efficiency bypass of DNA damage by human DNA polymerase Q
-
DOI 10.1038/sj.emboj.7600424
-
Seki M, Masutani C, Yang LW, et al. High-efficiency bypass of DNA damage by human DNA polymerase Q. EMBO J 2004;23:4484-4494 (Pubitemid 39601973)
-
(2004)
EMBO Journal
, vol.23
, Issue.22
, pp. 4484-4494
-
-
Seki, M.1
Masutani, C.2
Yang, L.W.3
Schuffert, A.4
Iwai, S.5
Bahar, I.6
Wood, R.D.7
-
33
-
-
27744483444
-
The translesion DNA polymerase θ plays a dominant role in immunoglobulin gene somatic hypermutation
-
DOI 10.1038/sj.emboj.7600833, PII 7600833
-
Zan H, Shima N, Xu Z, et al. The translesion DNA polymerase θ plays a dominant role in immunoglobulin gene somatic hypermutation. EMBO J 2005;24:3757-3769 (Pubitemid 41581692)
-
(2005)
EMBO Journal
, vol.24
, Issue.21
, pp. 3757-3769
-
-
Zan, H.1
Shima, N.2
Xu, Z.3
Al-Qahtani, A.4
Evinger III, A.J.5
Zhong, Y.6
Schimenti, J.C.7
Casali, P.8
-
34
-
-
33750028041
-
Absence of DNA polymerase θ results in decreased somatic hypermutation frequency and altered mutation patterns in Ig genes
-
Masuda K,Ouchida R, HikidaM, et al. Absence of DNA polymerase θ results in decreased somatic hypermutation frequency and altered mutation patterns in Ig genes. DNA Repair (Amst) 2006; 5:1384-1391
-
(2006)
DNA Repair (Amst)
, vol.5
, pp. 1384-1391
-
-
Masuda, K.1
Ouchida, R.2
Hikida, M.3
-
35
-
-
48149091758
-
Reevaluation of the role of DNA polymerase A in somatic hypermutation of immunoglobulin genes
-
Martomo SA, Saribasak H, Yokoi M, Hanaoka F, Gearhart PJ. Reevaluation of the role of DNA polymerase A in somatic hypermutation of immunoglobulin genes. DNA Repair (Amst) 2008;7:1603-1608
-
(2008)
DNA Repair (Amst)
, vol.7
, pp. 1603-1608
-
-
Martomo, S.A.1
Saribasak, H.2
Yokoi, M.3
Hanaoka, F.4
Gearhart, P.J.5
-
36
-
-
33749315817
-
Vertebrate POLQ and POLβ cooperate in base excision repair of oxidative DNA damage
-
Yoshimura M, Kohzaki M, Nakamura J, et al. Vertebrate POLQ and POLβ cooperate in base excision repair of oxidative DNA damage. Mol Cell 2006;24:115-125
-
(2006)
Mol Cell
, vol.24
, pp. 115-125
-
-
Yoshimura, M.1
Kohzaki, M.2
Nakamura, J.3
-
37
-
-
64549092249
-
Human DNA polymerase θ possesses 5′-dRP lyase activity and functions in single-nucleotide base excision repair in vitro
-
Prasad R, Longley MJ, Sharief FS, Hou EW, Copeland WC, Wilson SH. Human DNA polymerase θ possesses 5′-dRP lyase activity and functions in single-nucleotide base excision repair in vitro. Nucleic Acids Res 2009;37:1868-1877
-
(2009)
Nucleic Acids Res
, vol.37
, pp. 1868-1877
-
-
Prasad, R.1
Longley, M.J.2
Sharief, F.S.3
Hou, E.W.4
Copeland, W.C.5
Wilson, S.H.6
-
38
-
-
70349307403
-
Lack of DNA polymerase θ (POLQ) radiosensitizes bone marrow stromal cells in vitro and increases reticulocyte micronuclei after total-body irradiation
-
Goff JP, Shields DS, Seki M, et al. Lack of DNA polymerase θ (POLQ) radiosensitizes bone marrow stromal cells in vitro and increases reticulocyte micronuclei after total-body irradiation. Radiat Res 2009; 172:165-174
-
(2009)
Radiat Res
, vol.172
, pp. 165-174
-
-
Goff, J.P.1
Shields, D.S.2
Seki, M.3
|