Inhibition of transforming growth factor-β1 signaling attenuates ataxia telangiectasia mutated activity in response to genotoxic stress

Cancer Research

Volumn 66, Issue 22, 2006, Pages 10861-10869

  Kirshner, Julia ^a   Jobling, Michael F ^a   Pajares, Maria Jose ^a   Ravani, Shraddha A ^a   Glick, Adam B ^b   Lavin, Martin J ^c   Koslov, Sergei ^c   Shiloh, Yosef ^d   Barcellos Hoff, Mary Helen ^a,e  

^a LAWRENCE BERKELEY NATIONAL LABORATORY   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

^c ROYAL BRISBANE AND WOMEN'S HOSPITAL   (Australia)

^d TEL AVIV UNIVERSITY   (Israel)

^e Materials Sciences Division   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ATM PROTEIN; CHECKPOINT KINASE 2; ENZYME INHIBITOR; HISTONE H2AX; NUCLEIC ACID BINDING PROTEIN; PROTEIN P53; PROTEIN RAD17; TRANSFORMING GROWTH FACTOR BETA1; TUMOR GROWTH FACTOR BETA1 RECEPTOR KINSE INHIBITOR;

ANIMAL CELL; APOPTOSIS; ARTICLE; ATTENUATION; AUTOPHOSPHORYLATION; CANONICAL ANALYSIS; CARCINOGENESIS; CELL CYCLE ARREST; CELL FATE; DNA DAMAGE; ENZYME ACTIVITY; ENZYME INHIBITION; EPITHELIUM CELL; GENOMIC INSTABILITY; GENOTOXICITY; HOMEOSTASIS; HUMAN; HUMAN CELL; IRRADIATION; MOUSE; NONHUMAN; PLEIOTROPY; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; RADIATION RESPONSE; RADIOSENSITIVITY; SIGNAL TRANSDUCTION; STRESS;

ACTIVIN RECEPTORS, TYPE I; ANIMALS; CELL CYCLE; CELL CYCLE PROTEINS; DNA DAMAGE; DNA-BINDING PROTEINS; EPITHELIAL CELLS; HUMANS; INFRARED RAYS; KERATINOCYTES; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; RECEPTORS, TRANSFORMING GROWTH FACTOR BETA; SIGNAL TRANSDUCTION; TRANSFORMING GROWTH FACTOR BETA1; TUMOR SUPPRESSOR PROTEINS;

EID: 33845303212     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-06-2565     Document Type: Article

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