TGFβ-1 dependent fast stimulation of ATM and p53 phosphorylation following exposure to ionizing radiation does not involve TGFβ-receptor I signalling

Radiotherapy and Oncology

Volumn 83, Issue 3, 2007, Pages 289-295

  Wiegman, Erwin M ^a,b   Blaese, Marcel A ^a   Loeffler, Heidi ^a   Coppes, Rob P ^b   Rodemann, H Peter ^a  

^a UNIVERSITY OF TÜBINGEN   (Germany)

^b UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

Author keywords

ATM activity; TGF 1; TGF 1 receptor signalling

Indexed keywords

ATM PROTEIN; CHECKPOINT KINASE 2; DECANOYLARGINYLVALYLLYSYLARGINYLCHLOROMETHYL KETONE; FURIN; KETONE DERIVATIVE; PROTEIN P53; SMAD PROTEIN; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 1; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG; CELL CYCLE PROTEIN; DNA BINDING PROTEIN; PROTEIN SERINE THREONINE KINASE; SMAD2 PROTEIN; SMAD2 PROTEIN, HUMAN; TRANSFORMING GROWTH FACTOR BETA RECEPTOR; TUMOR SUPPRESSOR PROTEIN;

ARTICLE; CELL CYCLE ARREST; CELL SURVIVAL; CONTROLLED STUDY; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IONIZING RADIATION; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RADIATION EXPOSURE; SIGNAL TRANSDUCTION; CELL LINE; DRUG EFFECT; GENETICS; KINETICS; METABOLISM; PHOSPHORYLATION; TIME; UPREGULATION;

CELL CYCLE PROTEINS; CELL LINE; DNA-BINDING PROTEINS; FLOW CYTOMETRY; HUMANS; KINETICS; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; RADIATION, IONIZING; RECEPTORS, TRANSFORMING GROWTH FACTOR BETA; SIGNAL TRANSDUCTION; SMAD2 PROTEIN; TIME FACTORS; TRANSFORMING GROWTH FACTOR BETA1; TUMOR SUPPRESSOR PROTEIN P53; TUMOR SUPPRESSOR PROTEINS; UP-REGULATION;

EID: 34250189244     PISSN: 01678140     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.radonc.2007.05.013     Document Type: Article

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