The impact of a negligent G2/M checkpoint on genomic instability and cancer induction

Nature Reviews Cancer

Volumn 7, Issue 11, 2007, Pages 861-869

  Löbrich, Markus ^a   Jeggo, Penny A ^b  

^a DARMSTADT UNIVERSITY OF TECHNOLOGY   (Germany)

^b UNIVERSITY OF SUSSEX   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ATM PROTEIN; ATR PROTEIN; CHECKPOINT KINASE 2; DOUBLE STRANDED DNA;

CANCER RISK; CARCINOGENESIS; CELL CYCLE G1 PHASE; CELL CYCLE G2 PHASE; CHROMOSOME BREAKAGE; DNA DAMAGE; DNA RESPONSIVE ELEMENT; DNA STRAND BREAKAGE; GENOMIC INSTABILITY; HUMAN; MAMMAL; MITOSIS; NONHUMAN; PRIORITY JOURNAL; RADIATION DOSE; REVIEW; YEAST;

ANIMALS; APOPTOSIS; CELL CYCLE PROTEINS; CELL DIVISION; CELL TRANSFORMATION, NEOPLASTIC; DNA; DNA BREAKS, DOUBLE-STRANDED; DNA DAMAGE; DNA REPAIR; DNA-BINDING PROTEINS; G2 PHASE; GENES, CDC; GENOMIC INSTABILITY; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MODELS, BIOLOGICAL; PHOSPHORYLATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN-SERINE-THREONINE KINASES; RISK; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR PROTEINS;

EID: 35548978945     PISSN: 1474175X     EISSN: 14741768     Source Type: Journal    
DOI: 10.1038/nrc2248     Document Type: Review

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