The farnesyltransferase inhibitor L744,832 reduces hypoxia in tumors expressing activated H-ras

Cancer Research

Volumn 61, Issue 5, 2001, Pages 2289-2293

  Cohen Jonathan, E ^a   Evans, S M ^a   Koch, C J ^a   Muschel, R J ^a   McKenna, W G ^a   Wu, J ^a   Bernhard, E J ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 [[2 [[2 [(2 AMINO 3 MERCAPTOPROPYL)AMINO] 3 METHYLPENTYL]OXY] 1 OXO 3 PHENYLPROPYL]AMINO] 4 (METHYLSULFONYL)BUTANOIC ACID ISOPROPYL ESTER; 2 NITROIMIDAZOLE DERIVATIVE; PROTEIN FARNESYLTRANSFERASE INHIBITOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG SCREENING; HYPOXIA; MALIGNANT NEOPLASTIC DISEASE; MOUSE; NONHUMAN; ONCOGENE H RAS; PRIORITY JOURNAL; RADIOSENSITIZATION; TISSUE OXYGENATION; TUMOR XENOGRAFT;

ALKYL AND ARYL TRANSFERASES; ANIMALS; ANTINEOPLASTIC AGENTS; CELL HYPOXIA; ENZYME INHIBITORS; FARNESYLTRANSTRANSFERASE; GENE EXPRESSION; GENES, RAS; HT29 CELLS; HUMANS; METHIONINE; MICE; MICE, NUDE; MUTATION; NEOPLASMS; OXYGEN; RAS PROTEINS; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 0035266246     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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