Target of rapamycin (TOR): An integrator of nutrient and growth factor signals and coordinator of cell growth and cell cycle progression

Oncogene

Volumn 23, Issue 18, 2004, Pages 3151-3171

  Fingar, Diane C ^a,b   Blenis, John ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

4E BP1; Cell growth; Rapamycin; S6K1; TOR

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; AMINO ACID; BINDING PROTEIN; EVEROLIMUS; GROWTH FACTOR; IMATINIB; IMMUNOSUPPRESSIVE AGENT; INITIATION FACTOR; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHOTRANSFERASE; PROTEIN S6; RAPAMYCIN; RAS PROTEIN; TARGET OF RAPAMYCIN KINASE; TEMSIROLIMUS; TRANSLATION INITIATION FACTOR 4E; TUBERIN; TUMOR SUPPRESSOR PROTEIN; UNCLASSIFIED DRUG; WORTMANNIN; CARRIER PROTEIN; EIF4EBP1 PROTEIN, HUMAN; MAMMALIAN TARGET OF RAPAMYCIN; MONOMERIC GUANINE NUCLEOTIDE BINDING PROTEIN; NEUROPEPTIDE; PHOSPHOPROTEIN; PROTEIN; PROTEIN KINASE; REPRESSOR PROTEIN; RHEB PROTEIN, HUMAN; S6 KINASE; SIGNAL TRANSDUCING ADAPTOR PROTEIN; TUBEROUS SCLEROSIS COMPLEX 1 PROTEIN;

BIOSYNTHESIS; CARCINOGENESIS; CELL CYCLE; CELL GROWTH; CELL PROLIFERATION; CELL SIZE; CLINICAL TRIAL; DRUG APPROVAL; DRUG POTENCY; DRUG POTENTIATION; ENERGY; EUKARYOTE; FOOD AND DRUG ADMINISTRATION; HUMAN; NONHUMAN; NUTRIENT; ORGAN SIZE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN PHOSPHORYLATION; REVIEW; SEQUENCE HOMOLOGY; TUMOR; ANIMAL; CELL DIVISION; CHEMISTRY; METABOLISM; NEOPLASM; PHYSIOLOGY; PROTEIN SYNTHESIS; RIBOSOME; SIGNAL TRANSDUCTION;

ANIMALIA; EUKARYOTA; MAMMALIA; TOR;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; CARRIER PROTEINS; CELL CYCLE; CELL DIVISION; HUMANS; MONOMERIC GTP-BINDING PROTEINS; NEOPLASMS; NEUROPEPTIDES; PHOSPHOPROTEINS; PROTEIN BIOSYNTHESIS; PROTEIN KINASES; PROTEINS; REPRESSOR PROTEINS; RIBOSOMAL PROTEIN S6 KINASES; RIBOSOMES; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR PROTEINS;

EID: 2342545519     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1207542     Document Type: Review

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