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Proceedings of the National Academy of Sciences of the United States of America

Volumn 98, Issue 18, 2001, Pages 10320-10325

An inhibitor of mTOR reduces neoplasia and normalizes p70/s6 kinase activity in Pten+/- mice

(18) Podsypanina, Katrina a Lee, Richard T a Politis, Chris a Hennessy, Ian a Crane, Allison a Puc, Janusz a Neshat, Mehran b Wang, Hong c Yang, Lin a Gibbons, Jay d Frost, Phil d Dreisbach, Valley e Blenis, John e Gaciong, Zbigniew f Fisher, Peter a Sawyers, Charles b Hedrick Ellenson, Lora c Parsons, Ramon a

a College of Physicians and Surgeons ^* (United States)

b UNIVERSITY OF CALIFORNIA (United States)

c WEILL CORNELL MEDICAL COLLEGE (United States)

d PFIZER INC (United States)

e HARVARD MEDICAL SCHOOL (United States)

f MEDICAL UNIVERSITY OF WARSAW (Poland)

Author keywords

[No Author keywords available]

Indexed keywords

MAMMALIAN TARGET OF RAPAMYCIN; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN; PROTEIN INHIBITOR; RAPAMYCIN DERIVATIVE; S6 KINASE; TEMSIROLIMUS; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CANCER THERAPY; CARCINOGENESIS; CELL PROLIFERATION; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME ANALYSIS; MOUSE; NEOPLASM; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; TUMOR VOLUME;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ALLELES; ANIMALS; BASE SEQUENCE; CELL TRANSFORMATION, NEOPLASTIC; DNA PRIMERS; FEMALE; HUMANS; MICE; MICE, KNOCKOUT; PHOSPHORIC MONOESTER HYDROLASES; PROTEIN KINASE INHIBITORS; PROTEIN KINASES; PTEN PHOSPHOHYDROLASE; RIBOSOMAL PROTEIN S6 KINASES; SIGNAL TRANSDUCTION; SIROLIMUS; TUMOR SUPPRESSOR PROTEINS; UTERINE NEOPLASMS;

ANIMALIA;

EID: 17944368972 PISSN: 00278424 EISSN: None Source Type: Journal
DOI: 10.1073/pnas.171060098 Document Type: Article

Times cited : (571)

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