메뉴 건너뛰기




Volumn 14, Issue , 1996, Pages 483-510

Immunopharmacology of rapamycin

Author keywords

cell cycle; growth control; immunosuppression; lymphocyte activation; protein synthesis inhibitor

Indexed keywords

CALCINEURIN; IMMUNOSUPPRESSIVE AGENT; INTERLEUKIN 2; RAPAMYCIN; T LYMPHOCYTE RECEPTOR; TACROLIMUS;

EID: 0030010183     PISSN: 07320582     EISSN: None     Source Type: Book Series    
DOI: 10.1146/annurev.immunol.14.1.483     Document Type: Review
Times cited : (592)

References (20)
  • 1
    • 0016724057 scopus 로고
    • Rapamycin (AY-22,989), a new antifungal antibiotic. I. Taxonomy of the producing streptomycete and isolation of the active principle
    • Vezina C, Kudelski A, Sehgal SN. 1975. Rapamycin (AY-22,989), a new antifungal antibiotic. I. Taxonomy of the producing streptomycete and isolation of the active principle. J. Antibiot. 28:721-26
    • (1975) J. Antibiot. , vol.28 , pp. 721-726
    • Vezina, C.1    Kudelski, A.2    Sehgal, S.N.3
  • 2
    • 0016713286 scopus 로고
    • Rapamycin (AY-22,989), a new antifungal antibiotic. II. Fermentation, isolation and characterization
    • Sehgal SN, Baker H, Vezina C. 1975. Rapamycin (AY-22,989), a new antifungal antibiotic. II. Fermentation, isolation and characterization. J. Antibiot. 28:727-32
    • (1975) J. Antibiot. , vol.28 , pp. 727-732
    • Sehgal, S.N.1    Baker, H.2    Vezina, C.3
  • 3
    • 0018101547 scopus 로고
    • Rapamycin (AY-22,989), a new anti-fungal antibiotic. III. in vitro and in vivo evaluation
    • Baker H, Sidorowicz A, Sehgal SN, Vezina C. 1978. Rapamycin (AY-22,989), a new anti-fungal antibiotic. III. In vitro and in vivo evaluation. J. Antibiot. 31:539-45
    • (1978) J. Antibiot. , vol.31 , pp. 539-545
    • Baker, H.1    Sidorowicz, A.2    Sehgal, S.N.3    Vezina, C.4
  • 4
    • 0018606537 scopus 로고
    • Rapamycin (AY-22,989), a new antifungal antibiotic. IV. Mechanism of action
    • Singh K, Sun S, Vezina C. 1979. Rapamycin (AY-22,989), a new antifungal antibiotic. IV. Mechanism of action. J. Antibiot. 32:630-45
    • (1979) J. Antibiot. , vol.32 , pp. 630-645
    • Singh, K.1    Sun, S.2    Vezina, C.3
  • 5
    • 0021164348 scopus 로고
    • Activity of rapamycin (AY-22,989) against transplanted tumors
    • Eng CP, Sehgal SN, Vezina C. 1984. Activity of rapamycin (AY-22,989) against transplanted tumors. J. Antibiot. 37:1231-37
    • (1984) J. Antibiot. , vol.37 , pp. 1231-1237
    • Eng, C.P.1    Sehgal, S.N.2    Vezina, C.3
  • 6
    • 0018831901 scopus 로고
    • On the chemistry and high field nuclear magnetic resonance spectroscopy of rapamycin
    • Findlay JA, Radics L. 1980. On the chemistry and high field nuclear magnetic resonance spectroscopy of rapamycin. Can. J. Chem. 58:579-90
    • (1980) Can. J. Chem. , vol.58 , pp. 579-590
    • Findlay, J.A.1    Radics, L.2
  • 8
    • 0027521714 scopus 로고
    • Total synthesis of (-)-rapamycin using an Evans-Tishchenko fragment coupling
    • Romo D, Meyer SD, Johnson DD, Schreiber SL. 1993. Total synthesis of (-)-rapamycin using an Evans-Tishchenko fragment coupling. J. Am. Chem. Soc. 115:7906-7
    • (1993) J. Am. Chem. Soc. , vol.115 , pp. 7906-7907
    • Romo, D.1    Meyer, S.D.2    Johnson, D.D.3    Schreiber, S.L.4
  • 9
    • 0027495167 scopus 로고
    • Total synthesis of rapamycin via a novel titanium-mediated aldol macro-cyclization reaction
    • Hayward CM, Yohannes D, Danishefsky SJ. 1993. Total synthesis of rapamycin via a novel titanium-mediated aldol macro-cyclization reaction. J Am. Chem. Soc. 115:9345-16
    • (1993) J Am. Chem. Soc. , vol.115 , pp. 9345-9416
    • Hayward, C.M.1    Yohannes, D.2    Danishefsky, S.J.3
  • 11
    • 0017362502 scopus 로고
    • Inhibition of the immune response by rapamycin, a new antifungal antibiotic
    • Martel RR, Klicius J, Galet S. 1977. Inhibition of the immune response by rapamycin, a new antifungal antibiotic. Can. J. Physiol. 55:48-51
    • (1977) Can. J. Physiol. , vol.55 , pp. 48-51
    • Martel, R.R.1    Klicius, J.2    Galet, S.3
  • 12
    • 0023245677 scopus 로고
    • FK-506, a novel immunosuppressant isolated from a Streptomyces. I. Fermentation, isolation, and physico-chemical and biological characteristics
    • Kino R, Hatanaka H, Hashimoto M, Nishiyama M, Goto T, Okuhara M, Kohsaka M, Aoki H, Imanaka H. 1987. FK-506, a novel immunosuppressant isolated from a Streptomyces. I. Fermentation, isolation, and physico-chemical and biological characteristics. J Antibiot. (Tokyo). 40:1249-55
    • (1987) J Antibiot. (Tokyo) , vol.40 , pp. 1249-1255
    • Kino, R.1    Hatanaka, H.2    Hashimoto, M.3    Nishiyama, M.4    Goto, T.5    Okuhara, M.6    Kohsaka, M.7    Aoki, H.8    Imanaka, H.9
  • 15
    • 0024345850 scopus 로고
    • Identification of a new pharmacologic action for an old compound
    • Morris RE, Meiser BM. 1989. Identification of a new pharmacologic action for an old compound. Med. Sci. Res. 17:609-10
    • (1989) Med. Sci. Res. , vol.17 , pp. 609-610
    • Morris, R.E.1    Meiser, B.M.2
  • 16
    • 0025022365 scopus 로고
    • The immunosuppressive macrolides FK-506 and rapamycin act as reciprocal antagonists in murine T cells
    • Dumont F, Melino M, Staruch M, Koprak S, Fischer P, Sigal N. 1990. The immunosuppressive macrolides FK-506 and rapamycin act as reciprocal antagonists in murine T cells. J. Immunol. 144:1418-24
    • (1990) J. Immunol. , vol.144 , pp. 1418-1424
    • Dumont, F.1    Melino, M.2    Staruch, M.3    Koprak, S.4    Fischer, P.5    Sigal, N.6
  • 17
    • 0025099697 scopus 로고
    • Distinct mechanisms of suppression of murine T cell activation by the related macrolides FK-506 and rapamycin
    • Dumont F, Staruch M, Koprak S, Melino M, Sigal N. 1990. Distinct mechanisms of suppression of murine T cell activation by the related macrolides FK-506 and rapamycin. J. Immunol. 144:251-58
    • (1990) J. Immunol. , vol.144 , pp. 251-258
    • Dumont, F.1    Staruch, M.2    Koprak, S.3    Melino, M.4    Sigal, N.5
  • 19
    • 0025735273 scopus 로고
    • Rapamycin: FK506's fraternal twin or distant cousin? Immunol
    • Morris RE. 1991. Rapamycin: FK506's fraternal twin or distant cousin? Immunol. Today. 12:137-40
    • (1991) Today. , vol.12 , pp. 137-140
    • Morris, R.E.1
  • 20
    • 0026071875 scopus 로고
    • Inhibition of skin graft rejection in mice by rapamycin: A novel immunosuppressive macrolide
    • Eng CP, Gullo-Brown J, Chang JY, Sehgal SN. 1991. Inhibition of skin graft rejection in mice by rapamycin: a novel immunosuppressive macrolide. Transplant. Proc. 23:868-69
    • (1991) Transplant. Proc. , vol.23 , pp. 868-869
    • Eng, C.P.1    Gullo-Brown, J.2    Chang, J.Y.3    Sehgal, S.N.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.