Lethality of Drosophila lacking TSC tumor suppressor function rescued by reducing ds6K signaling

Genes and Development

Volumn 16, Issue 20, 2002, Pages 2627-2632

  Radimerski, Thomas ^a   Montagne, Jacques ^a   Hemmings Mieszczak, Maja ^b   Thomas, George ^a  

^a FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH   (Switzerland)

^b NOVARTIS PHARMA AG   (Switzerland)

Author keywords

Growth; PKB; PTEN; S6K; TOR; TSC

Indexed keywords

HAMARTIN; TUBERIN;

ANIMAL CELL; ARTICLE; DROSOPHILA; GENE FUNCTION; GENE MUTATION; GENETIC DISORDER; GENOTYPE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; TUBEROUS SCLEROSIS; TUMOR SUPPRESSOR GENE;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; CELL DIVISION; DOWN-REGULATION; DROSOPHILA MELANOGASTER; ENZYME ACTIVATION; EYE; GENES, INSECT; GENES, LETHAL; GENES, TUMOR SUPPRESSOR; MUTATION; PHOSPHATIDYLINOSITOL PHOSPHATES; PHOSPHORIC MONOESTER HYDROLASES; PROTEIN-SERINE-THREONINE KINASES; PROTEIN-TYROSINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; PTEN PHOSPHOHYDROLASE; RIBOSOMAL PROTEIN S6 KINASES; RNA, DOUBLE-STRANDED; SIGNAL TRANSDUCTION; TUBEROUS SCLEROSIS; TUMOR SUPPRESSOR PROTEINS; WING;

ANIMALIA;

EID: 0037108151     PISSN: 08909369     EISSN: None     Source Type: Journal    
DOI: 10.1101/gad.239102     Document Type: Article

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