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Volumn 23, Issue 23, 2003, Pages 8862-8877

mTOR-Dependent Regulation of Ribosomal Gene Transcription Requires S6K1 and Is Mediated by Phosphorylation of the Carboxy-Terminal Activation Domain of the Nucleolar Transcription Factor UBF

Author keywords

[No Author keywords available]

Indexed keywords

MAMMALIAN TARGET OF RAPAMYCIN; RAPAMYCIN; REGULATOR PROTEIN; RIBOSOME DNA; S6 KINASE; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR SL 1; TRANSCRIPTION FACTOR UBF; UNCLASSIFIED DRUG;

EID: 0242637318     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.23.23.8862-8877.2003     Document Type: Article
Times cited : (376)

References (67)
  • 1
    • 0034252226 scopus 로고    scopus 로고
    • TIF-IA, the factor mediating growth-dependent control of ribosomal RNA synthesis, is the mammalian homolog of yeast Rrn3p
    • Bodem, J., G. Dobreva, U. Hoffmann-Rohrer, S. Iben, H. Zentgraf, H. Delius, M. Vingron, and I. Grummt. 2000. TIF-IA, the factor mediating growth-dependent control of ribosomal RNA synthesis, is the mammalian homolog of yeast Rrn3p. EMBO Rep. 1:171-175.
    • (2000) EMBO Rep. , vol.1 , pp. 171-175
    • Bodem, J.1    Dobreva, G.2    Hoffmann-Rohrer, U.3    Iben, S.4    Zentgraf, H.5    Delius, H.6    Vingron, M.7    Grummt, I.8
  • 2
    • 0035462613 scopus 로고    scopus 로고
    • Increased expression of UBF is a critical determinant for rRNA synthesis and hypertrophic growth of cardiac myocytes
    • Brandenburger, Y., A. Jenkins, D. J. Autelitano, and R. D. Hannan. 2001. Increased expression of UBF is a critical determinant for rRNA synthesis and hypertrophic growth of cardiac myocytes. FASEB J. 15:2051-2053.
    • (2001) FASEB J. , vol.15 , pp. 2051-2053
    • Brandenburger, Y.1    Jenkins, A.2    Autelitano, D.J.3    Hannan, R.D.4
  • 3
    • 0033000334 scopus 로고    scopus 로고
    • s6k integrates phosphatidylinositol 3-kinase and rapamycin-regulated signals for E2F regulation in T lymphocytes
    • s6k integrates phosphatidylinositol 3-kinase and rapamycin-regulated signals for E2F regulation in T lymphocytes. Mol. Cell. Biol. 19:4729-4738.
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 4729-4738
    • Brennan, P.1    Babbage, J.W.2    Thomas, G.3    Cantrell, D.4
  • 4
    • 0022768818 scopus 로고
    • Transcriptional role for the nontranscribed spacer of rat ribosomal DNA
    • Cassidy, B. G., H. F. Yang-Yen, and L. I. Rothblum. 1986. Transcriptional role for the nontranscribed spacer of rat ribosomal DNA. Mol. Cell. Biol. 6:2766-2773.
    • (1986) Mol. Cell. Biol. , vol.6 , pp. 2766-2773
    • Cassidy, B.G.1    Yang-Yen, H.F.2    Rothblum, L.I.3
  • 6
    • 0032548942 scopus 로고    scopus 로고
    • Differential regulation by calcium reveals distinct signaling requirements for the activation of Akt and p70S6k
    • Conus, N. M., B. A. Hemmings, and R. B. Pearson. 1998. Differential regulation by calcium reveals distinct signaling requirements for the activation of Akt and p70S6k. J. Biol. Chem. 273:4776-4782.
    • (1998) J. Biol. Chem. , vol.273 , pp. 4776-4782
    • Conus, N.M.1    Hemmings, B.A.2    Pearson, R.B.3
  • 7
    • 0027983480 scopus 로고
    • Positive regulation of the cAMP-responsive activator CREM by the p70 S6 kinase: An alternative route to mitogen-induced gene expression
    • de Groot, R. P., L. M. Ballou, and P. Sassone-Corsi. 1994. Positive regulation of the cAMP-responsive activator CREM by the p70 S6 kinase: an alternative route to mitogen-induced gene expression. Cell 79:81-91.
    • (1994) Cell , vol.79 , pp. 81-91
    • De Groot, R.P.1    Ballou, L.M.2    Sassone-Corsi, P.3
  • 8
    • 0037097863 scopus 로고    scopus 로고
    • Mammalian cell size is controlled by mTOR and its downstream targets S6K1 and 4EBP1/eIF4E
    • Fingar, D. C., S. Salama, C. Tsou, E. Harlow, and J. Blenis. 2002. Mammalian cell size is controlled by mTOR and its downstream targets S6K1 and 4EBP1/eIF4E. Genes Dev. 16:1472-1487.
    • (2002) Genes Dev. , vol.16 , pp. 1472-1487
    • Fingar, D.C.1    Salama, S.2    Tsou, C.3    Harlow, E.4    Blenis, J.5
  • 9
    • 0035233058 scopus 로고    scopus 로고
    • Control of translation by the target of rapamycin proteins
    • Gingras, A. C., B. Raught, and N. Sonenberg. 2001. Control of translation by the target of rapamycin proteins. Prog. Mol. Subcell. Biol. 27:143-174.
    • (2001) Prog. Mol. Subcell. Biol. , vol.27 , pp. 143-174
    • Gingras, A.C.1    Raught, B.2    Sonenberg, N.3
  • 10
    • 0035312747 scopus 로고    scopus 로고
    • Regulation of translation initiation by FRAP/mTOR
    • Gingras, A. C., B. Raught, and N. Sonenberg. 2001. Regulation of translation initiation by FRAP/mTOR. Genes Dev. 15:807-826.
    • (2001) Genes Dev. , vol.15 , pp. 807-826
    • Gingras, A.C.1    Raught, B.2    Sonenberg, N.3
  • 11
    • 0028958587 scopus 로고
    • The RNA polymerase I transcription factor UBF is the product of a primary response gene
    • Glibetic, M., L. Taylor, D. Larson, R. Hannan, B. Sells, and L. Rothblum. 1995. The RNA polymerase I transcription factor UBF is the product of a primary response gene. J. Biol. Chem. 270:4209-4212.
    • (1995) J. Biol. Chem. , vol.270 , pp. 4209-4212
    • Glibetic, M.1    Taylor, L.2    Larson, D.3    Hannan, R.4    Sells, B.5    Rothblum, L.6
  • 12
    • 0023234937 scopus 로고
    • Isolation, fractionation and reconstitution of a nuclear extract capable of transcribing ribosomal DNA
    • Haglund, R. E., and L. I. Rothblum. 1987. Isolation, fractionation and reconstitution of a nuclear extract capable of transcribing ribosomal DNA. Mol. Cell. Biochem. 73:11-20.
    • (1987) Mol. Cell. Biochem. , vol.73 , pp. 11-20
    • Haglund, R.E.1    Rothblum, L.I.2
  • 13
    • 0029081544 scopus 로고
    • Rapamycin, wortmannin, and the methylxanthine SQ20006 inactivate pT0s6k by p70s6k by inducing dephosphorylation of the same subset of sites
    • Han, J. W., R. B. Pearson, P. B. Dennis, and G. Thomas. 1995. Rapamycin, wortmannin, and the methylxanthine SQ20006 inactivate pT0s6k by p70s6k by inducing dephosphorylation of the same subset of sites. J. Biol. Chem. 270:21396-21403.
    • (1995) J. Biol. Chem. , vol.270 , pp. 21396-21403
    • Han, J.W.1    Pearson, R.B.2    Dennis, P.B.3    Thomas, G.4
  • 15
    • 0034691675 scopus 로고    scopus 로고
    • RNA polymerase I transcription in confluent cells: Rb downregulates rDNA transcription during confluence-induced cell cycle arrest
    • Hannan, K. M., B. K. Kennedy, A. H. Cavanaugh, R. D. Hannan, I. Hirschler-Laszkiewicz, L. S. Jefferson, and L. I. Rothblum. 2000. RNA polymerase I transcription in confluent cells: Rb downregulates rDNA transcription during confluence-induced cell cycle arrest. Oncogene 19:3487-3497.
    • (2000) Oncogene , vol.19 , pp. 3487-3497
    • Hannan, K.M.1    Kennedy, B.K.2    Cavanaugh, A.H.3    Hannan, R.D.4    Hirschler-Laszkiewicz, I.5    Jefferson, L.S.6    Rothblum, L.I.7
  • 16
    • 0037337449 scopus 로고    scopus 로고
    • Activation of S6K1 (p70 ribosomal protein S6 kinase 1) requires an initial calcium-dependent priming event involving formation of a high-molecular-mass signalling complex
    • Hannan, K. M., G. Thomas, and R. B. Pearson. 2003. Activation of S6K1 (p70 ribosomal protein S6 kinase 1) requires an initial calcium-dependent priming event involving formation of a high-molecular-mass signalling complex. Biochem. J. 370:469-477.
    • (2003) Biochem. J. , vol.370 , pp. 469-477
    • Hannan, K.M.1    Thomas, G.2    Pearson, R.B.3
  • 17
    • 0033557150 scopus 로고    scopus 로고
    • Cellular regulation of ribosomal DNA transcription: Both rat and Xenopus UBF1 stimulate rDNA transcription in 3T3 fibroblasts
    • Hannan, R., V. Stefanovsky, T. Arino, L. Rothblum, and T. Moss. 1999. Cellular regulation of ribosomal DNA transcription: both rat and Xenopus UBF1 stimulate rDNA transcription in 3T3 fibroblasts. Nucleic Acids Res. 27:1205-1213.
    • (1999) Nucleic Acids Res. , vol.27 , pp. 1205-1213
    • Hannan, R.1    Stefanovsky, V.2    Arino, T.3    Rothblum, L.4    Moss, T.5
  • 19
    • 0028918980 scopus 로고
    • Regulation of rDNA transcription factors during cardiomyocyte hypertrophy induced by adrenergic agents
    • Hannan, R. D., J. Luyken, and L. I. Rothblum. 1995. Regulation of rDNA transcription factors during cardiomyocyte hypertrophy induced by adrenergic agents. J. Biol. Chem. 270:8290-8297.
    • (1995) J. Biol. Chem. , vol.270 , pp. 8290-8297
    • Hannan, R.D.1    Luyken, J.2    Rothblum, L.I.3
  • 20
    • 0030041763 scopus 로고    scopus 로고
    • Regulation of ribosomal DNA transcription during contraction-induced hypertrophy of neonatal cardiomyocytes
    • Hannan, R. D., J. Luyken, and L. I. Rothblum. 1996. Regulation of ribosomal DNA transcription during contraction-induced hypertrophy of neonatal cardiomyocytes. J. Biol. Chem. 271:3213-3220.
    • (1996) J. Biol. Chem. , vol.271 , pp. 3213-3220
    • Hannan, R.D.1    Luyken, J.2    Rothblum, L.I.3
  • 21
    • 0029738630 scopus 로고    scopus 로고
    • Overexpression of the transcription factor UBF1 is sufficient to increase ribosomal DNA transcription in neonatal cardiomyocytes: Implications for cardiac hypertrophy
    • Hannan, R. D., V. Stefanovsky, L. Taylor, T. Moss, and L. I. Rothblum. 1996. Overexpression of the transcription factor UBF1 is sufficient to increase ribosomal DNA transcription in neonatal cardiomyocytes: implications for cardiac hypertrophy. Proc. Natl. Acad. Sci. USA 93:8750-8755.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 8750-8755
    • Hannan, R.D.1    Stefanovsky, V.2    Taylor, L.3    Moss, T.4    Rothblum, L.I.5
  • 22
    • 0035859956 scopus 로고    scopus 로고
    • p70S6 kinase signals cell survival as well as growth, inactivating the proapoptotic molecule BAD
    • Harada, H., J. S. Andersen, M. Mann, N. Terada, and S. J. Korsmeyer. 2001. p70S6 kinase signals cell survival as well as growth, inactivating the proapoptotic molecule BAD. Proc. Natl. Acad. Sci. USA 98:9666-9670.
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 9666-9670
    • Harada, H.1    Andersen, J.S.2    Mann, M.3    Terada, N.4    Korsmeyer, S.J.5
  • 23
    • 0030061161 scopus 로고    scopus 로고
    • The species-specific RNA polymerase I transcription factor SL-1 binds to upstream binding factor
    • Hempel, W. M., A. H. Cavanaugh, R. D. Hannan, L. Taylor, and L. I. Rothblum. 1996. The species-specific RNA polymerase I transcription factor SL-1 binds to upstream binding factor. Mol. Cell. Biol. 16:557-563.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 557-563
    • Hempel, W.M.1    Cavanaugh, A.H.2    Hannan, R.D.3    Taylor, L.4    Rothblum, L.I.5
  • 24
    • 0028810245 scopus 로고
    • Angiotensin II-induced hypertrophy of rat vascular smooth muscle is associated with increased 18 S rRNA synthesis and phosphorylation of the rRNA transcription factor, upstream binding factor
    • Hershey, J. C., M. Hautmann, M. M. Thompson, L. I. Rothblum, T. A. Haystead, and G. K. Owens. 1995. Angiotensin II-induced hypertrophy of rat vascular smooth muscle is associated with increased 18 S rRNA synthesis and phosphorylation of the rRNA transcription factor, upstream binding factor. J. Biol. Chem. 270:25096-25101.
    • (1995) J. Biol. Chem. , vol.270 , pp. 25096-25101
    • Hershey, J.C.1    Hautmann, M.2    Thompson, M.M.3    Rothblum, L.I.4    Haystead, T.A.5    Owens, G.K.6
  • 27
    • 0032442607 scopus 로고    scopus 로고
    • Phosphorylation of the rRNA transcription factor upstream binding factor promotes its association with TATA binding protein
    • Kihm, A. J., J. C. Hershey, T. A. J. Haystead, C. S. Madsen, and G. K. Owens. 1998. Phosphorylation of the rRNA transcription factor upstream binding factor promotes its association with TATA binding protein. Proc. Natl. Acad. Sci. USA 95:14816-14820.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 14816-14820
    • Kihm, A.J.1    Hershey, J.C.2    Haystead, T.A.J.3    Madsen, C.S.4    Owens, G.K.5
  • 28
    • 0036007421 scopus 로고    scopus 로고
    • Regulation of cell size in growth, development and human disease: PI3K, PKB and S6K
    • Kozma, S. C., and G. Thomas. 2002. Regulation of cell size in growth, development and human disease: PI3K, PKB and S6K. Bioessays 24:65-71.
    • (2002) Bioessays , vol.24 , pp. 65-71
    • Kozma, S.C.1    Thomas, G.2
  • 29
    • 0016248333 scopus 로고
    • A short lived polypeptide component of one of two discrete functional pools of hepatic nuclear alpha-amanitin resistant RNA polymerases
    • Lampert, A., and P. Feigelson. 1974. A short lived polypeptide component of one of two discrete functional pools of hepatic nuclear alpha-amanitin resistant RNA polymerases. Biochem. Biophys. Res. Commun. 58:1030-1038.
    • (1974) Biochem. Biophys. Res. Commun. , vol.58 , pp. 1030-1038
    • Lampert, A.1    Feigelson, P.2
  • 30
    • 0027336002 scopus 로고
    • p70s6k function is essential for G1 progression
    • Lane, H. A., A. Fernandez, N. J. Lamb, and G. Thomas. 1993. p70s6k function is essential for G1 progression. Nature 363:170-172.
    • (1993) Nature , vol.363 , pp. 170-172
    • Lane, H.A.1    Fernandez, A.2    Lamb, N.J.3    Thomas, G.4
  • 31
    • 0026059316 scopus 로고
    • Cyanogen bromide cleavage and proteolytic peptide mapping of proteins immobilized to membranes
    • Luo, K. X., T. R. Hurley, and B. M. Sefton. 1991. Cyanogen bromide cleavage and proteolytic peptide mapping of proteins immobilized to membranes. Methods Enzymol. 201:149-152.
    • (1991) Methods Enzymol. , vol.201 , pp. 149-152
    • Luo, K.X.1    Hurley, T.R.2    Sefton, B.M.3
  • 32
    • 0030023510 scopus 로고    scopus 로고
    • Regulation of rDNA transcription during endothelin-1-induced hypertrophy of neonatal cardiomyocytes. Hyperphosphorylation of upstream binding factor, an rDNA transcription factor
    • Luyken, J., R. D. Hannan, J. Y. Cheung, and L. I. Rothblum. 1996. Regulation of rDNA transcription during endothelin-1-induced hypertrophy of neonatal cardiomyocytes. Hyperphosphorylation of upstream binding factor, an rDNA transcription factor. Circ. Res. 78:354-361.
    • (1996) Circ. Res. , vol.78 , pp. 354-361
    • Luyken, J.1    Hannan, R.D.2    Cheung, J.Y.3    Rothblum, L.I.4
  • 33
    • 0027931137 scopus 로고
    • Modulation of transcription of rRNA genes by rapamycin
    • Mahajan, P. B. 1994. Modulation of transcription of rRNA genes by rapamycin. Int. J. Immunopharmacol. 16:711-721.
    • (1994) Int. J. Immunopharmacol. , vol.16 , pp. 711-721
    • Mahajan, P.B.1
  • 35
    • 0034712932 scopus 로고    scopus 로고
    • RNA polymerase I transcription factor Rrn3 is functionally conserved between yeast and human
    • Moorefield, B., E. A. Greene, and R. H. Reeder. 2000. RNA polymerase I transcription factor Rrn3 is functionally conserved between yeast and human. Proc. Natl. Acad. Sci. USA 97:4724-4729.
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 4724-4729
    • Moorefield, B.1    Greene, E.A.2    Reeder, R.H.3
  • 36
    • 0037205270 scopus 로고    scopus 로고
    • At the center of eukaryotic life
    • Moss, T., and V. Y. Stefanovsky. 2002. At the center of eukaryotic life. Cell 109:545-548.
    • (2002) Cell , vol.109 , pp. 545-548
    • Moss, T.1    Stefanovsky, V.Y.2
  • 37
    • 0029170117 scopus 로고
    • Promotion and regulation of ribosomal transcription in eukaryotes by RNA polymerase I
    • Moss, T., and V. Y. Stefanovsky. 1995. Promotion and regulation of ribosomal transcription in eukaryotes by RNA polymerase I. Prog. Nucleic Acid Res. Mol. Biol. 50:25-66.
    • (1995) Prog. Nucleic Acid Res. Mol. Biol. , vol.50 , pp. 25-66
    • Moss, T.1    Stefanovsky, V.Y.2
  • 38
    • 0031743906 scopus 로고    scopus 로고
    • Connections between growth and the cell cycle
    • Neufeld, T. P., and B. A. Edgar. 1998. Connections between growth and the cell cycle. Curr. Opin. Cell Biol. 10:784-790.
    • (1998) Curr. Opin. Cell Biol. , vol.10 , pp. 784-790
    • Neufeld, T.P.1    Edgar, B.A.2
  • 39
    • 0026502471 scopus 로고
    • Differential phosphorylation and localization of the transcription factor UBF in vivo in response to serum deprivation. In vitro dephosphorylation of UBF reduces its transactivation properties
    • O'Mahony, D. J., W. Q. Xie, S. D. Smith, H. A. Singer, and L. I. Rothblum. 1992. Differential phosphorylation and localization of the transcription factor UBF in vivo in response to serum deprivation. In vitro dephosphorylation of UBF reduces its transactivation properties. J. Biol. Chem. 267:35-38.
    • (1992) J. Biol. Chem. , vol.267 , pp. 35-38
    • O'Mahony, D.J.1    Xie, W.Q.2    Smith, S.D.3    Singer, H.A.4    Rothblum, L.I.5
  • 41
    • 0028802451 scopus 로고
    • The principal target of rapamycin-induced p70s6k inactivation is a novel phosphorylation site within a conserved hydrophobic domain
    • Pearson, R. B., P. B. Dennis, J. W. Han, N. A. Williamson, S. C. Kozma, R. E. Wettenhall, and G. Thomas. 1995. The principal target of rapamycin-induced p70s6k inactivation is a novel phosphorylation site within a conserved hydrophobic domain. EMBO J. 14:5279-5287.
    • (1995) EMBO J. , vol.14 , pp. 5279-5287
    • Pearson, R.B.1    Dennis, P.B.2    Han, J.W.3    Williamson, N.A.4    Kozma, S.C.5    Wettenhall, R.E.6    Thomas, G.7
  • 42
    • 0029418405 scopus 로고
    • Regulation of p70s6k/p85s6k and its role in the cell cycle
    • Pearson, R. B., and G. Thomas. 1995. Regulation of p70s6k/p85s6k and its role in the cell cycle. Prog. Cell Cycle Res. 1:21-32.
    • (1995) Prog. Cell Cycle Res. , vol.1 , pp. 21-32
    • Pearson, R.B.1    Thomas, G.2
  • 43
    • 0033551234 scopus 로고    scopus 로고
    • Protein phosphatase 2A interacts with the 70-kDa S6 kinase and is activated by inhibition of FKBP12-rapamycin-associated protein
    • Peterson, R. T., B. N. Desai, J. S. Hardwick, and S. L. Schreiber. 1999. Protein phosphatase 2A interacts with the 70-kDa S6 kinase and is activated by inhibition of FKBP12-rapamycin-associated protein. Proc. Natl. Acad. Sci. USA 96:4438-4442.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 4438-4442
    • Peterson, R.T.1    Desai, B.N.2    Hardwick, J.S.3    Schreiber, S.L.4
  • 44
    • 0032915417 scopus 로고    scopus 로고
    • Regulation of ribosome biogenesis by the rapamycin-sensitive TOR-signaling pathway in Saccharomyces cerevisiae
    • Powers, T., and P. Walter. 1999. Regulation of ribosome biogenesis by the rapamycin-sensitive TOR-signaling pathway in Saccharomyces cerevisiae. Mol. Biol. Cell 10:987-1000.
    • (1999) Mol. Biol. Cell , vol.10 , pp. 987-1000
    • Powers, T.1    Walter, P.2
  • 45
    • 0037108151 scopus 로고    scopus 로고
    • Lethality of Drosophila lacking TSC tumor suppressor function rescued by reducing dS6K signaling
    • Radimerski, T., J. Montagne, M. Hemmings-Mieszczak, and G. Thomas. 2002. Lethality of Drosophila lacking TSC tumor suppressor function rescued by reducing dS6K signaling. Genes Dev. 16:2627-2632.
    • (2002) Genes Dev. , vol.16 , pp. 2627-2632
    • Radimerski, T.1    Montagne, J.2    Hemmings-Mieszczak, M.3    Thomas, G.4
  • 48
    • 0020491426 scopus 로고
    • Transcription initiation site of rat ribosomal DNA
    • Rothblum, L. I., R. Reddy, and B. Cassidy. 1982. Transcription initiation site of rat ribosomal DNA. Nucleic Acids Res. 10:7345-7362.
    • (1982) Nucleic Acids Res. , vol.10 , pp. 7345-7362
    • Rothblum, L.I.1    Reddy, R.2    Cassidy, B.3
  • 49
    • 0034644525 scopus 로고    scopus 로고
    • TOR, a central controller of cell growth
    • Schmelzle, T., and M. N. Hall. 2000. TOR, a central controller of cell growth. Cell 103:253-262.
    • (2000) Cell , vol.103 , pp. 253-262
    • Schmelzle, T.1    Hall, M.N.2
  • 51
    • 0027130985 scopus 로고
    • Transcription from the rat 45S ribosomal DNA promoter does not require the factor UBF
    • Smith, S. D., D. J. O'Mahony, B. T. Kinsella, and L. I. Rothblum. 1993. Transcription from the rat 45S ribosomal DNA promoter does not require the factor UBF. Gene Expr. 3:229-236.
    • (1993) Gene Expr. , vol.3 , pp. 229-236
    • Smith, S.D.1    O'Mahony, D.J.2    Kinsella, B.T.3    Rothblum, L.I.4
  • 53
    • 0032054816 scopus 로고    scopus 로고
    • The mRNA 5′ cap-binding protein eIF4E and control of cell growth
    • Sonenberg, N., and A. C. Gingras. 1998. The mRNA 5′ cap-binding protein eIF4E and control of cell growth. Curr. Opin. Cell Biol. 10:268-275.
    • (1998) Curr. Opin. Cell Biol. , vol.10 , pp. 268-275
    • Sonenberg, N.1    Gingras, A.C.2
  • 54
    • 0035930330 scopus 로고    scopus 로고
    • An immediate response of ribosomal transcription to growth factor stimulation in mammals is mediated by ERK phosphorylation of UBF
    • Stefanovsky, V. Y., G. Pelletier, R. Hannan, T. Gagnon-Kugler, L. I. Rothblum, and T. Moss. 2001. An immediate response of ribosomal transcription to growth factor stimulation in mammals is mediated by ERK phosphorylation of UBF. Mol. Cell 8:1063-1073.
    • (2001) Mol. Cell , vol.8 , pp. 1063-1073
    • Stefanovsky, V.Y.1    Pelletier, G.2    Hannan, R.3    Gagnon-Kugler, T.4    Rothblum, L.I.5    Moss, T.6
  • 55
    • 0032563947 scopus 로고    scopus 로고
    • Size control: Cell proliferation does not equal growth
    • Su, T. T., and P. H. O'Farrell. 1998. Size control: cell proliferation does not equal growth. Curr. Biol. 8:R687-R689.
    • (1998) Curr. Biol. , vol.8
    • Su, T.T.1    O'Farrell, P.H.2
  • 56
    • 0035200856 scopus 로고    scopus 로고
    • Amino acid-induced translation of TOP mRNAs is fully dependent on phosphatidylinositol 3-kinase-mediated signaling, is partially inhibited by rapamycin, and is independent of S6K1 and rpS6 phosphorylation
    • Tang, H., E. Hornstein, M. Stolovich, G. Levy, M. Livingstone, D. Templeton, J. Avruch, and O. Meyuhas. 2001. Amino acid-induced translation of TOP mRNAs is fully dependent on phosphatidylinositol 3-kinase-mediated signaling, is partially inhibited by rapamycin, and is independent of S6K1 and rpS6 phosphorylation. Mol. Cell. Biol. 21:8671-8683.
    • (2001) Mol. Cell. Biol. , vol.21 , pp. 8671-8683
    • Tang, H.1    Hornstein, E.2    Stolovich, M.3    Levy, G.4    Livingstone, M.5    Templeton, D.6    Avruch, J.7    Meyuhas, O.8
  • 57
    • 0033772338 scopus 로고    scopus 로고
    • An encore for ribosome biogenesis in the control of cell proliferation
    • Thomas, G. 2000. An encore for ribosome biogenesis in the control of cell proliferation. Nat. Cell Biol. 2:E71-E72.
    • (2000) Nat. Cell Biol. , vol.2
    • Thomas, G.1
  • 58
    • 0030707562 scopus 로고    scopus 로고
    • TOR signalling and control of cell growth
    • Thomas, G., and M. N. Hall. 1997. TOR signalling and control of cell growth. Curr. Opin. Cell Biol. 9:782-787.
    • (1997) Curr. Opin. Cell Biol. , vol.9 , pp. 782-787
    • Thomas, G.1    Hall, M.N.2
  • 59
    • 0030029587 scopus 로고    scopus 로고
    • Protein kinase CK2: Biphasic kinetics with peptide substrates
    • Tiganis, T., C. M. House, and B. E. Kemp. 1996. Protein kinase CK2: biphasic kinetics with peptide substrates. Arch. Biochem. Biophys. 325:289-294.
    • (1996) Arch. Biochem. Biophys. , vol.325 , pp. 289-294
    • Tiganis, T.1    House, C.M.2    Kemp, B.E.3
  • 60
    • 0032936298 scopus 로고    scopus 로고
    • Recruitment of TATA-binding protein-TAFI complex SL1 to the human ribosomal DNA promoter is mediated by the carboxy-terminal activation domain of upstream binding factor (UBF) and is regulated by UBF phosphorylation
    • Tuan, J. C., W. Zhai, and L. Comai. 1999. Recruitment of TATA-binding protein-TAFI complex SL1 to the human ribosomal DNA promoter is mediated by the carboxy-terminal activation domain of upstream binding factor (UBF) and is regulated by UBF phosphorylation. Mol. Cell. Biol. 19:2872-2879.
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 2872-2879
    • Tuan, J.C.1    Zhai, W.2    Comai, L.3
  • 61
    • 0029094210 scopus 로고
    • Activation of mammalian ribosomal gene transcription requires phosphorylation of the nucleolar transcription factor UBF
    • Voit, R., A. Kuhn, E. E. Sander, and I. Grummt. 1995. Activation of mammalian ribosomal gene transcription requires phosphorylation of the nucleolar transcription factor UBF. Nucleic Acids Res. 23:2593-2599.
    • (1995) Nucleic Acids Res. , vol.23 , pp. 2593-2599
    • Voit, R.1    Kuhn, A.2    Sander, E.E.3    Grummt, I.4
  • 62
    • 0026591023 scopus 로고
    • The nucleolar transcription factor mUBF is phosphorylated by casein kinase II in the C-terminal hyperacidic tail which is essential for transactivation
    • Voit, R., A. Schnapp, A. Kuhn, H. Rosenbauer, P. Hirschmann, H. G. Stunnenberg, and I. Grummt. 1992. The nucleolar transcription factor mUBF is phosphorylated by casein kinase II in the C-terminal hyperacidic tail which is essential for transactivation. EMBO J. 11:2211-2218.
    • (1992) EMBO J. , vol.11 , pp. 2211-2218
    • Voit, R.1    Schnapp, A.2    Kuhn, A.3    Rosenbauer, H.4    Hirschmann, P.5    Stunnenberg, H.G.6    Grummt, I.7
  • 64
    • 0032514376 scopus 로고    scopus 로고
    • Translational induction of the c-myc oncogene via activation of the FRAP/TOR signalling pathway
    • West, M. J., M. Stoneley, and A. E. Willis. 1998. Translational induction of the c-myc oncogene via activation of the FRAP/TOR signalling pathway. Oncogene 17:769-780.
    • (1998) Oncogene , vol.17 , pp. 769-780
    • West, M.J.1    Stoneley, M.2    Willis, A.E.3
  • 65
    • 0034535175 scopus 로고    scopus 로고
    • Cdc42 stimulates RNA splicing via the S6 kinase and a novel S6 kinase target, the nuclear cap-binding complex
    • Wilson, K. F., W. J. Wu, and R. A. Cerione. 2000. Cdc42 stimulates RNA splicing via the S6 kinase and a novel S6 kinase target, the nuclear cap-binding complex. J. Biol. Chem. 275:37307-37310.
    • (2000) J. Biol. Chem. , vol.275 , pp. 37307-37310
    • Wilson, K.F.1    Wu, W.J.2    Cerione, R.A.3
  • 66
    • 0031596416 scopus 로고    scopus 로고
    • 0 program of transcriptional repression in yeast by interfering with the TOR signaling pathway
    • 0 program of transcriptional repression in yeast by interfering with the TOR signaling pathway. Mol. Cell. Biol. 18:4463-4470.
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 4463-4470
    • Zaragoza, D.1    Ghavidel, A.2    Heitman, J.3    Schultz, M.C.4
  • 67
    • 0037291736 scopus 로고    scopus 로고
    • ERK-dependent phosphorylation of the transcription initiation factor TIF-IA is required for RNA polymerase I transcription and cell growth
    • Zhao, J., X. Yuan, M. Frodin, and I. Grummt. 2003. ERK-dependent phosphorylation of the transcription initiation factor TIF-IA is required for RNA polymerase I transcription and cell growth. Mol. Cell 11:405-413.
    • (2003) Mol. Cell , vol.11 , pp. 405-413
    • Zhao, J.1    Yuan, X.2    Frodin, M.3    Grummt, I.4


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