Drosophila tumor suppressor PTEN controls cell size and number by antagonizing the Chico/PI3-kinase signaling pathway

Genes and Development

Volumn 13, Issue 24, 1999, Pages 3244-3258

  Goberdhan, Deborah C I ^a   Paricio, Nuria ^b   Goodman, Emma C ^a   Mlodzik, Marek ^b   Wilson, Clive ^a  

^a UNIVERSITY OF KENT   (United Kingdom)

^b EUROPEAN MOLECULAR BIOLOGY LABORATORY   (Germany)

Author keywords

Actin cytoskeleton; Akt PKB; Cell proliferation; Growth control; Insulin signaling; PI3 kinase

Indexed keywords

COMPLEMENTARY DNA; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE; PHOSPHOPROTEIN PHOSPHATASE;

ANIMAL CELL; ARTICLE; CELL PROLIFERATION; CYTOSKELETON; DROSOPHILA; ENZYME ACTIVITY; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR GENE;

1-PHOSPHATIDYLINOSITOL 3-KINASE; AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; CARRIER PROTEINS; CELL DIVISION; CELL SIZE; CHROMOSOME MAPPING; CYTOSKELETON; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; ETHYL METHANESULFONATE; EYE; GENES, TUMOR SUPPRESSOR; GENOMIC LIBRARY; GERM-LINE MUTATION; HOMOZYGOTE; HUMANS; INSECT PROTEINS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MOLECULAR SEQUENCE DATA; MUTAGENESIS; PHOSPHORIC MONOESTER HYDROLASES; PTEN PHOSPHOHYDROLASE; SIGNAL TRANSDUCTION; TRANSCRIPTION, GENETIC; TUMOR SUPPRESSOR PROTEINS; WING;

EID: 0033572644     PISSN: 08909369     EISSN: None     Source Type: Journal    
DOI: 10.1101/gad.13.24.3244     Document Type: Article

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