메뉴 건너뛰기




Volumn 13, Issue 15, 2003, Pages 1259-1268

Erratum: Tuberous Sclerosis Complex Gene Products, Tuberin and Hamartin, Control mTOR Signaling by Acting as a GTPase-Activating Protein Complex toward Rheb (Current Biology (2003) 13(15) (1259–1268), (S0960982203005062), (10.1016/S0960-9822(03)00506-2));Tuberous Sclerosis Complex gene products, Tuberin and Hamartin, control mTOR signaling by acting as a GTPase-activating protein complex toward Rheb

Author keywords

[No Author keywords available]

Indexed keywords

EUKARYOTA; MAMMALIA;

EID: 0042701991     PISSN: 09609822     EISSN: 18790445     Source Type: Journal    
DOI: 10.1016/j.cub.2022.01.027     Document Type: Erratum
Times cited : (1013)

References (49)
  • 2
    • 0027992456 scopus 로고
    • 9q34 loss of heterozygosity in atuberous sclerosis astrocytoma suggests a growth suppressor-like activity also for the TSC1 gene
    • Carbonara, C., Longa, L., Grosso, E., Borrone, C., Garre, M.G., Brisigotti, M., and Migone, N. (1994). 9q34 loss of heterozygosity in atuberous sclerosis astrocytoma suggests a growth suppressor-like activity also for the TSC1 gene. Hum. Mol. Genet. 3, 1829-1832.
    • (1994) Hum. Mol. Genet. , vol.3 , pp. 1829-1832
    • Carbonara, C.1    Longa, L.2    Grosso, E.3    Borrone, C.4    Garre, M.G.5    Brisigotti, M.6    Migone, N.7
  • 3
    • 0028289473 scopus 로고
    • Loss of heterozygosity on chromosome 16p13.3 in hamartomas from tuberous sclerosis patients
    • Green, A.J., Smith, M., and Yates, J.R. (1994). Loss of heterozygosity on chromosome 16p13.3 in hamartomas from tuberous sclerosis patients. Nat. Genet. 6, 193-196.
    • (1994) Nat. Genet. , vol.6 , pp. 193-196
    • Green, A.J.1    Smith, M.2    Yates, J.R.3
  • 4
    • 0028029278 scopus 로고
    • The tuberous sclerosis gene on chromosome 9q34 acts as a growth suppressor
    • Green, A.J., Johnson, P.H., and Yates, J.R. (1994). The tuberous sclerosis gene on chromosome 9q34 acts as a growth suppressor. Hum. Mol. Genet. 3, 1833-1834.
    • (1994) Hum. Mol. Genet. , vol.3 , pp. 1833-1834
    • Green, A.J.1    Johnson, P.H.2    Yates, J.R.3
  • 5
    • 0033582748 scopus 로고    scopus 로고
    • Gigas, a Drosophila homolog of tuberous sclerosis gene product-2, regulates the cell cycle
    • Ito, N., and Rubin, G.M. (1999). Gigas, a Drosophila homolog of tuberous sclerosis gene product-2, regulates the cell cycle. Cell 96, 529-539.
    • (1999) Cell , vol.96 , pp. 529-539
    • Ito, N.1    Rubin, G.M.2
  • 6
    • 0032741978 scopus 로고    scopus 로고
    • Tsc2(+/-) mice develop tumors in multiple sites that express gelsolin and are influenced by genetic background
    • Onda, H., Lueck, A., Marks, P.W., Warren, H.B., and Kwiatkowski, D.J. (1999). Tsc2(+/-) mice develop tumors in multiple sites that express gelsolin and are influenced by genetic background. J. Clin. Invest. 104, 687-695.
    • (1999) J. Clin. Invest. , vol.104 , pp. 687-695
    • Onda, H.1    Lueck, A.2    Marks, P.W.3    Warren, H.B.4    Kwiatkowski, D.J.5
  • 9
    • 0033775869 scopus 로고    scopus 로고
    • The TSC1 tumour suppressor hamartin regulates cell adhesion through ERM proteins and the GTPase Rho
    • Lamb, R.F., Roy, C., Diefenbach, T.J., Vinters, H.V., Johnson, M.W., Jay, D.G., and Hall, A. (2000). The TSC1 tumour suppressor hamartin regulates cell adhesion through ERM proteins and the GTPase Rho. Nat. Cell Biol. 2, 281-287.
    • (2000) Nat. Cell Biol. , vol.2 , pp. 281-287
    • Lamb, R.F.1    Roy, C.2    Diefenbach, T.J.3    Vinters, H.V.4    Johnson, M.W.5    Jay, D.G.6    Hall, A.7
  • 10
    • 0029021621 scopus 로고
    • Identification of tuberin, the tuberous sclerosis-2 product. Tuberin possesses specific Rap1GAP activity
    • Wienecke, R., Konig, A., and DeClue, J.E. (1995). Identification of tuberin, the tuberous sclerosis-2 product. Tuberin possesses specific Rap1GAP activity. J. Biol. Chem. 270, 16409-16414.
    • (1995) J. Biol. Chem. , vol.270 , pp. 16409-16414
    • Wienecke, R.1    Konig, A.2    DeClue, J.E.3
  • 11
    • 0030972969 scopus 로고    scopus 로고
    • The tuberous sclerosis 2 gene product, tuberin, functions as a Rab5 GTPase activating protein (GAP) in modulating endocytosis
    • Xiao, G.H., Shoarinejad, F., Jin, F., Goiemis, E.A., and Yeung, R.S. (1997). The tuberous sclerosis 2 gene product, tuberin, functions as a Rab5 GTPase activating protein (GAP) in modulating endocytosis. J. Biol. Chem. 272, 6097-6100.
    • (1997) J. Biol. Chem. , vol.272 , pp. 6097-6100
    • Xiao, G.H.1    Shoarinejad, F.2    Jin, F.3    Goiemis, E.A.4    Yeung, R.S.5
  • 12
    • 0037028305 scopus 로고    scopus 로고
    • Tuberin, the tuberous sclerosis complex 2 tumor suppressor gene product, regulates Rho activation, cell adhesion and migration
    • Astrinidis, A., Cash, T.P., Hunter, D.S., Walker, C.L., Chernoff, J., and Henske, E.P. (2002). Tuberin, the tuberous sclerosis complex 2 tumor suppressor gene product, regulates Rho activation, cell adhesion and migration. Oncogene 21, 8470-8476.
    • (2002) Oncogene , vol.21 , pp. 8470-8476
    • Astrinidis, A.1    Cash, T.P.2    Hunter, D.S.3    Walker, C.L.4    Chernoff, J.5    Henske, E.P.6
  • 13
    • 0035805162 scopus 로고    scopus 로고
    • Drosophila Tsc1 functions with Tsc2 to antagonize insulin signaling in regulating cell growth, cell proliferation, and organ size
    • Potter, C.J., Huang, H., and Xu, T. (2001). Drosophila Tsc1 functions with Tsc2 to antagonize insulin signaling in regulating cell growth, cell proliferation, and organ size. Cell 105, 357-368.
    • (2001) Cell , vol.105 , pp. 357-368
    • Potter, C.J.1    Huang, H.2    Xu, T.3
  • 14
    • 0034982971 scopus 로고    scopus 로고
    • TSC1 and TSC2 tumor suppressors antagonize insulin signaling in cell growth
    • Gao, X., and Pan, D. (2001). TSC1 and TSC2 tumor suppressors antagonize insulin signaling in cell growth. Genes Dev. 15, 1383-1392.
    • (2001) Genes Dev. , vol.15 , pp. 1383-1392
    • Gao, X.1    Pan, D.2
  • 15
    • 0034312315 scopus 로고    scopus 로고
    • Regulation of cellular growth by the Drosophila target of rapamycin dTOR
    • Zhang, H., Stallock, J.P., Ng, J.C., Reinhard, C., and Neufeld, T.P. (2000). Regulation of cellular growth by the Drosophila target of rapamycin dTOR. Genes Dev. 14, 2712-2724.
    • (2000) Genes Dev. , vol.14 , pp. 2712-2724
    • Zhang, H.1    Stallock, J.P.2    Ng, J.C.3    Reinhard, C.4    Neufeld, T.P.5
  • 16
    • 0036342294 scopus 로고    scopus 로고
    • Identification of the tuberous sclerosis complex-2 tumor suppressor gene product tuberin as a target of the phosphoinositide 3-kinase/akt pathway
    • Manning, B.D., Tee, A.R., Logsdon, M.N., Blenis, J., and Cantley, L.C. (2002). Identification of the tuberous sclerosis complex-2 tumor suppressor gene product tuberin as a target of the phosphoinositide 3-kinase/akt pathway. Mol. Cell 10, 151-162.
    • (2002) Mol. Cell , vol.10 , pp. 151-162
    • Manning, B.D.1    Tee, A.R.2    Logsdon, M.N.3    Blenis, J.4    Cantley, L.C.5
  • 17
    • 0036713778 scopus 로고    scopus 로고
    • TSC2 is phosphoryiated and inhibited by Akt and suppresses mTOR signalling
    • Inoki, K., Li, Y., Zhu, T., Wu, J., and Guan, K.L. (2002). TSC2 is phosphoryiated and inhibited by Akt and suppresses mTOR signalling. Nat. Cell Biol. 4, 648-657.
    • (2002) Nat. Cell Biol. , vol.4 , pp. 648-657
    • Inoki, K.1    Li, Y.2    Zhu, T.3    Wu, J.4    Guan, K.L.5
  • 19
    • 0037108750 scopus 로고    scopus 로고
    • Tuberous sclerosis complex-1 and -2 gene products function together to inhibit mammalian target of rapamycin (mTOR)-mediated downstream signaling
    • Tee, A.R., Fingar, D.C., Manning, B.D., Kwiatkowski, D.J., Cantley, L.C., and Blenis, J. (2002). Tuberous sclerosis complex-1 and -2 gene products function together to inhibit mammalian target of rapamycin (mTOR)-mediated downstream signaling. Proc. Natl. Acad. Sci. USA 99, 13571-13576.
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 13571-13576
    • Tee, A.R.1    Fingar, D.C.2    Manning, B.D.3    Kwiatkowski, D.J.4    Cantley, L.C.5    Blenis, J.6
  • 20
    • 0037097863 scopus 로고    scopus 로고
    • Mammalian cell size is controlled by mTOR and its downstream targets S6K1 and 4EBP1/eIF4E
    • Fingar, D.C., Salama, S., Tsou, C., Harlow, E., and Blenis, J. (2002). Mammalian cell size is controlled by mTOR and its downstream targets S6K1 and 4EBP1/eIF4E. Genes Dev. 16, 1472-1487.
    • (2002) Genes Dev. , vol.16 , pp. 1472-1487
    • Fingar, D.C.1    Salama, S.2    Tsou, C.3    Harlow, E.4    Blenis, J.5
  • 21
    • 0037662713 scopus 로고    scopus 로고
    • Regulation of targets of mTOR (mammalian target of rapamycin) signalling by intracellular amino acid availability
    • Beugnet, A., Tee, A.R., Taylor, P.M., and Proud, C.G. (2003). Regulation of targets of mTOR (mammalian target of rapamycin) signalling by intracellular amino acid availability. Biochem. J. 372, 555-566.
    • (2003) Biochem. J. , vol.372 , pp. 555-566
    • Beugnet, A.1    Tee, A.R.2    Taylor, P.M.3    Proud, C.G.4
  • 23
    • 0034051278 scopus 로고    scopus 로고
    • Loss of Rhb1, a Rheb-related GTPase in fission yeast, causes growth arrest with a terminal phenotype similar to that caused by nitrogen starvation
    • Mach, K.E., Furge, K.A., and Albright, C.F. (2000). Loss of Rhb1, a Rheb-related GTPase in fission yeast, causes growth arrest with a terminal phenotype similar to that caused by nitrogen starvation. Genetics 155, 611-622.
    • (2000) Genetics , vol.155 , pp. 611-622
    • Mach, K.E.1    Furge, K.A.2    Albright, C.F.3
  • 24
    • 0034646618 scopus 로고    scopus 로고
    • The Saccharomyces cerevisiae Rheb G-protein is involved in regulating canavanine resistance and arginine uptake
    • Urano, J., Tabancay, A.P., Yang, W., and Tamanoi, F. (2000). The Saccharomyces cerevisiae Rheb G-protein is involved in regulating canavanine resistance and arginine uptake. J. Biol. Chem. 275, 11198-11206.
    • (2000) J. Biol. Chem. , vol.275 , pp. 11198-11206
    • Urano, J.1    Tabancay, A.P.2    Yang, W.3    Tamanoi, F.4
  • 25
    • 0028237671 scopus 로고
    • Rheb, a growth factor- and synaptic activity-regulated gene, encodes a novel Ras-related protein
    • Yamagata, K., Sanders, L.K., Kaufmann, W.E., Yee, W., Barnes, C.A., Nathans, D., and Worley, P.F. (1994). Rheb, a growth factor- and synaptic activity-regulated gene, encodes a novel Ras-related protein. J. Biol. Chem. 269, 16333-16339.
    • (1994) J. Biol. Chem. , vol.269 , pp. 16333-16339
    • Yamagata, K.1    Sanders, L.K.2    Kaufmann, W.E.3    Yee, W.4    Barnes, C.A.5    Nathans, D.6    Worley, P.F.7
  • 26
    • 0030888163 scopus 로고    scopus 로고
    • The Ras-related protein Rheb is farnesylated and antagonizes Ras signaling and transformation
    • Clark, G.J., Kinch, M.S., Rogers-Graham, K., Sebti, S.M., Hamilton, A.D., and Der, C.J. (1997). The Ras-related protein Rheb is farnesylated and antagonizes Ras signaling and transformation. J. Biol. Chem. 272, 10608-10615.
    • (1997) J. Biol. Chem. , vol.272 , pp. 10608-10615
    • Clark, G.J.1    Kinch, M.S.2    Rogers-Graham, K.3    Sebti, S.M.4    Hamilton, A.D.5    Der, C.J.6
  • 28
    • 0026659046 scopus 로고
    • Rapamycin-FKBP specifically blocks growth-dependent activation of and signaling by the 70 kd S6 protein kinases
    • Chung, J., Kuo, C.J., Crabtree, G.R., and Blenis, J. (1992). Rapamycin-FKBP specifically blocks growth-dependent activation of and signaling by the 70 kd S6 protein kinases. Cell 69, 1227-1236.
    • (1992) Cell , vol.69 , pp. 1227-1236
    • Chung, J.1    Kuo, C.J.2    Crabtree, G.R.3    Blenis, J.4
  • 29
    • 0036385637 scopus 로고    scopus 로고
    • Coordinate regulation of translation by the PI 3-kinase and mTOR pathways
    • Martin, K.A., and Blenis, J. (2002). Coordinate regulation of translation by the PI 3-kinase and mTOR pathways. Adv. Cancer Res. 86, 1-39.
    • (2002) Adv. Cancer Res. , vol.86 , pp. 1-39
    • Martin, K.A.1    Blenis, J.2
  • 30
    • 2142817395 scopus 로고
    • Stimulation of ribosomal protein S6 kinase activity by pp60v-src or by serum: Dissociation from phorbol ester-stimulated activity
    • Blenis, J., and Erikson, R.L. (1986). Stimulation of ribosomal protein S6 kinase activity by pp60v-src or by serum: dissociation from phorbol ester-stimulated activity. Proc. Natl. Acad. Sci. USA 83, 1733-1737.
    • (1986) Proc. Natl. Acad. Sci. USA , vol.83 , pp. 1733-1737
    • Blenis, J.1    Erikson, R.L.2
  • 31
    • 0035312747 scopus 로고    scopus 로고
    • Regulation of translation initiation by FRAP/mTOR
    • Gingras, A.C., Raught, B., and Sonenberg, N. (2001). Regulation of translation initiation by FRAP/mTOR. Genes Dev. 15, 807-826.
    • (2001) Genes Dev. , vol.15 , pp. 807-826
    • Gingras, A.C.1    Raught, B.2    Sonenberg, N.3
  • 32
    • 0037117409 scopus 로고    scopus 로고
    • Identification of a conserved motif required for mTOR signaling
    • Schalm, S.S., and Blenis, J. (2002). Identification of a conserved motif required for mTOR signaling. Curr. Biol. 12, 632-639.
    • (2002) Curr. Biol. , vol.12 , pp. 632-639
    • Schalm, S.S.1    Blenis, J.2
  • 33
    • 0037174828 scopus 로고    scopus 로고
    • Characterization of phosphatidylinositol 3-kinase-dependent phosphorylation of the hydrophobic motif site Thr(389) in p70 S6 kinase 1
    • Romanelli, A., Dreisbach, V.C., and Blenis, J. (2002). Characterization of phosphatidylinositol 3-kinase-dependent phosphorylation of the hydrophobic motif site Thr(389) in p70 S6 kinase 1. J. Biol. Chem. 277, 40281-40289.
    • (2002) J. Biol. Chem. , vol.277 , pp. 40281-40289
    • Romanelli, A.1    Dreisbach, V.C.2    Blenis, J.3
  • 34
    • 0034797345 scopus 로고    scopus 로고
    • Failure to farnesylate Rheb protein contributes to the enrichment of G0/G1 phase cells in the Schizosaccharomyces pombe farnesyltransferase mutant
    • Yang, W., Tabancay, A.P., Jr., Urano, J., and Tamanoi, F. (2001). Failure to farnesylate Rheb protein contributes to the enrichment of G0/G1 phase cells in the Schizosaccharomyces pombe farnesyltransferase mutant. Mol. Microbiol. 41, 1339-1347.
    • (2001) Mol. Microbiol. , vol.41 , pp. 1339-1347
    • Yang, W.1    Tabancay A.P., Jr.2    Urano, J.3    Tamanoi, F.4
  • 35
    • 0029089593 scopus 로고
    • Ras-effector interactions, the problem of specificity
    • Wittinghofer, A., and Herrmann, C. (1995). Ras-effector interactions, the problem of specificity. FEBS Lett. 369, 52-56.
    • (1995) FEBS Lett. , vol.369 , pp. 52-56
    • Wittinghofer, A.1    Herrmann, C.2
  • 38
    • 0038643484 scopus 로고    scopus 로고
    • Rheb promotes cell growth as a component of the insulin/TOR signalling network
    • Saucedo, L.J., Gao, X., Chiarelli, D.A., Li, L., Pan, D., and Edgar, B.A. (2003). Rheb promotes cell growth as a component of the insulin/TOR signalling network. Nat. Cell Biol. 5, 566-571.
    • (2003) Nat. Cell Biol. , vol.5 , pp. 566-571
    • Saucedo, L.J.1    Gao, X.2    Chiarelli, D.A.3    Li, L.4    Pan, D.5    Edgar, B.A.6
  • 39
    • 0038141979 scopus 로고    scopus 로고
    • Rheb is a direct target of the tuberous sclerosis tumour suppressor proteins
    • Zhang, Y., Gao, X., Saucedo, L.J., Ru, B., Edgar, B.A., and Pan, D. (2003). Rheb is a direct target of the tuberous sclerosis tumour suppressor proteins. Nat. Cell Biol. 5, 578-581.
    • (2003) Nat. Cell Biol. , vol.5 , pp. 578-581
    • Zhang, Y.1    Gao, X.2    Saucedo, L.J.3    Ru, B.4    Edgar, B.A.5    Pan, D.6
  • 40
    • 0024406286 scopus 로고
    • All ras proteins are polyisoprenylated but only some are palmitoylated
    • Hancock, J.F., Magee, A.I., Childs, J.E., and Marshall, C.J. (1989). All ras proteins are polyisoprenylated but only some are palmitoylated. Cell 57, 1167-1177.
    • (1989) Cell , vol.57 , pp. 1167-1177
    • Hancock, J.F.1    Magee, A.I.2    Childs, J.E.3    Marshall, C.J.4
  • 41
    • 0032213545 scopus 로고    scopus 로고
    • Hamartin, the product of the tuberous sclerosis 1 (TSC1) gene, interacts with tuberin and appears to be localized to cytoplasmic vesicles
    • Plank, T.L., Yeung, R.S., and Henske, E.P. (1998). Hamartin, the product of the tuberous sclerosis 1 (TSC1) gene, interacts with tuberin and appears to be localized to cytoplasmic vesicles. Cancer Res. 58, 4766-4770.
    • (1998) Cancer Res. , vol.58 , pp. 4766-4770
    • Plank, T.L.1    Yeung, R.S.2    Henske, E.P.3
  • 43
    • 0022255075 scopus 로고
    • Activation of Ha-ras p21 by substitution, deletion, and insertion mutations
    • Chipperfield, R.G., Jones, S.S., Lo, K.M., and Weinberg, R.A. (1985). Activation of Ha-ras p21 by substitution, deletion, and insertion mutations. Mol. Cell. Biol. 5, 1809-1813.
    • (1985) Mol. Cell. Biol. , vol.5 , pp. 1809-1813
    • Chipperfield, R.G.1    Jones, S.S.2    Lo, K.M.3    Weinberg, R.A.4
  • 45
    • 0034785929 scopus 로고    scopus 로고
    • Characterization of regulatory events associated with membrane targeting of p90 ribosomal S6 kinase 1
    • Richards, S.A., Dreisbach, V.C., Murphy, L.O., and Blenis, J. (2001). Characterization of regulatory events associated with membrane targeting of p90 ribosomal S6 kinase 1. Mol. Cell. Biol. 21, 7470-7480.
    • (2001) Mol. Cell. Biol. , vol.21 , pp. 7470-7480
    • Richards, S.A.1    Dreisbach, V.C.2    Murphy, L.O.3    Blenis, J.4
  • 46
    • 0033615078 scopus 로고    scopus 로고
    • Ribosomal S6 kinase 1 (RSK1) activation requires signals dependent on and independent of the MAP kinase ERK
    • Richards, S.A., Fu, J., Romanelli, A., Shimamura, A., and Blenis, J. (1999). Ribosomal S6 kinase 1 (RSK1) activation requires signals dependent on and independent of the MAP kinase ERK. Curr. Biol. 9, 810-820.
    • (1999) Curr. Biol. , vol.9 , pp. 810-820
    • Richards, S.A.1    Fu, J.2    Romanelli, A.3    Shimamura, A.4    Blenis, J.5
  • 47
    • 0035896643 scopus 로고    scopus 로고
    • Regulation of ribosomal S6 kinase 2 by effectors of the phosphoinositide 3-kinase pathway
    • Martin, K.A., Schalm, S.S., Richardson, C., Romanelli, A., Keon, K.L., and Blenis, J. (2001). Regulation of ribosomal S6 kinase 2 by effectors of the phosphoinositide 3-kinase pathway. J. Biol. Chem. 276, 7884-7891.
    • (2001) J. Biol. Chem. , vol.276 , pp. 7884-7891
    • Martin, K.A.1    Schalm, S.S.2    Richardson, C.3    Romanelli, A.4    Keon, K.L.5    Blenis, J.6
  • 48
    • 0034628612 scopus 로고    scopus 로고
    • Rsk1 mediates a MEK-MAP kinase cell survival signal
    • Shimamura, A., Ballif, B.A., Richards, S.A., and Blenis, J. (2000). Rsk1 mediates a MEK-MAP kinase cell survival signal. Curr. Biol. 10, 127-135.
    • (2000) Curr. Biol. , vol.10 , pp. 127-135
    • Shimamura, A.1    Ballif, B.A.2    Richards, S.A.3    Blenis, J.4
  • 49
    • 0029100197 scopus 로고
    • Measurement of nucleotide exchange and hydrolysis activities in immunoprecipitates
    • W.E. Balch, C.J. Der, and A. Hall, ed. (London: Academic Press)
    • Downward, J. (1995). Measurement of nucleotide exchange and hydrolysis activities in immunoprecipitates. In Methods in Enzymology, vol. 255, W.E. Balch, C.J. Der, and A. Hall, ed. (London: Academic Press), pp. 110-117.
    • (1995) Methods in Enzymology , vol.255 , pp. 110-117
    • Downward, J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.