-
1
-
-
0034820160
-
Autophagy in yeast: Mechanistic insights and physiological function
-
Abeliovich, H., and D. J. Klionsky. 2001. Autophagy in yeast: Mechanistic insights and physiological function. Microbiol. Mol. Biol. Rev. 65:463-479.
-
(2001)
Microbiol. Mol. Biol. Rev.
, vol.65
, pp. 463-479
-
-
Abeliovich, H.1
Klionsky, D.J.2
-
2
-
-
0035449355
-
Cell cycle checkpoint signaling through the ATM and ATR kinases
-
Abraham, R. T. 2001. Cell cycle checkpoint signaling through the ATM and ATR kinases. Genes Dev. 15:2177-2196.
-
(2001)
Genes Dev.
, vol.15
, pp. 2177-2196
-
-
Abraham, R.T.1
-
3
-
-
0032802378
-
Protein kinase activity and identification of a toxic effector domain of the target of rapamycin TOR proteins in yeast
-
Alarcon, C. M., J. Heitman, and M. E. Cardenas. 1999. Protein kinase activity and identification of a toxic effector domain of the target of rapamycin TOR proteins in yeast. Mol. Biol. Cell 10:2531-2546.
-
(1999)
Mol. Biol. Cell
, vol.10
, pp. 2531-2546
-
-
Alarcon, C.M.1
Heitman, J.2
Cardenas, M.E.3
-
4
-
-
0035196663
-
The target of rapamycin signaling pathway regulates mRNA turnover in the yeast Saccharomyces cerevisiae
-
Albig, A. R., and C. J. Decker. 2001. The target of rapamycin signaling pathway regulates mRNA turnover in the yeast Saccharomyces cerevisiae. Mol. Biol. Cell 12:3428-3438.
-
(2001)
Mol. Biol. Cell
, vol.12
, pp. 3428-3438
-
-
Albig, A.R.1
Decker, C.J.2
-
5
-
-
0029392854
-
HEAT repeats in the Huntington's disease protein
-
Andrade, M. A., and P. Bork. 1995. HEAT repeats in the Huntington's disease protein. Nat. Genet. 11:115-116.
-
(1995)
Nat. Genet.
, vol.11
, pp. 115-116
-
-
Andrade, M.A.1
Bork, P.2
-
6
-
-
0030974986
-
Rapamycin destabilizes interleukin-3 mRNA in autocrine tumor cells by a mechanism requiring an intact 3′ untranslated region
-
Banholzer, R., A. P. Nair, H. H. Hirsch, X. F. Ming, and C. Moroni. 1997. Rapamycin destabilizes interleukin-3 mRNA in autocrine tumor cells by a mechanism requiring an intact 3′ untranslated region. Mol. Cell. Biol. 17:3254-3260.
-
(1997)
Mol. Cell. Biol.
, vol.17
, pp. 3254-3260
-
-
Banholzer, R.1
Nair, A.P.2
Hirsch, H.H.3
Ming, X.F.4
Moroni, C.5
-
8
-
-
0033540030
-
The TOR signalling pathway controls nuclear localization of nutrient-regulated transcription factors
-
Beck, T., and M. N. Hall. 1999. The TOR signalling pathway controls nuclear localization of nutrient-regulated transcription factors. Nature 402: 689-692.
-
(1999)
Nature
, vol.402
, pp. 689-692
-
-
Beck, T.1
Hall, M.N.2
-
9
-
-
0033588918
-
Starvation induces vacuolar targeting and degradation of the tryptophan permease in yeast
-
Beck, T., A. Schmidt, and M. N. Hall. 1999. Starvation induces vacuolar targeting and degradation of the tryptophan permease in yeast. J. Cell Biol. 146:1227-1238.
-
(1999)
J. Cell Biol.
, vol.146
, pp. 1227-1238
-
-
Beck, T.1
Schmidt, A.2
Hall, M.N.3
-
10
-
-
0030066934
-
Rapamycin blocks the phosphorylation of 4E-BP1 and inhibits cap-dependent initiation of translation
-
Beretta, L., A. C. Gingras, Y. V. Svitkin, M. N. Hall, and N. Sonenberg. 1996. Rapamycin blocks the phosphorylation of 4E-BP1 and inhibits cap-dependent initiation of translation. EMBO J. 15:658-664.
-
(1996)
EMBO J.
, vol.15
, pp. 658-664
-
-
Beretta, L.1
Gingras, A.C.2
Svitkin, Y.V.3
Hall, M.N.4
Sonenberg, N.5
-
11
-
-
0034705026
-
Drosophila Thor participates in host immune defense and connects a translational regulator with innate immunity
-
Bernal, A., and D. A. Kimbrell. 2000. Drosophila Thor participates in host immune defense and connects a translational regulator with innate immunity. Proc. Natl. Acad. Sci. USA 97:6019-6024.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 6019-6024
-
-
Bernal, A.1
Kimbrell, D.A.2
-
12
-
-
0032516080
-
The TOR (target of rapamycin) signal transduction pathway regulates the stability of translation initiation factor eIF4G in the yeast Saccharomyces cerevisiae
-
Berset, C., H. Trachsel, and M. Altmann. 1998. The TOR (target of rapamycin) signal transduction pathway regulates the stability of translation initiation factor eIF4G in the yeast Saccharomyces cerevisiae. Proc. Natl. Acad. Sci. USA 95:4264-4269.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 4264-4269
-
-
Berset, C.1
Trachsel, H.2
Altmann, M.3
-
13
-
-
0032548058
-
The 14-3-3 proteins positively regulate rapamycin-sensitive signaling
-
Bertram, P. G., C. Zeng, J. Thorson, A. S. Shaw, and X. F. Zheng. 1998. The 14-3-3 proteins positively regulate rapamycin-sensitive signaling. Curr. Biol. 8:1259-1267.
-
(1998)
Curr. Biol.
, vol.8
, pp. 1259-1267
-
-
Bertram, P.G.1
Zeng, C.2
Thorson, J.3
Shaw, A.S.4
Zheng, X.F.5
-
14
-
-
0025226638
-
Probing immunosuppressant action with a nonnatural immunophilin ligand
-
Bierer, B. E., P. K. Somers, T. J. Wandless, S. J. Burakoff, and S. L. Schreiber. 1990. Probing immunosuppressant action with a nonnatural immunophilin ligand. Science 250:556-559.
-
(1990)
Science
, vol.250
, pp. 556-559
-
-
Bierer, B.E.1
Somers, P.K.2
Wandless, T.J.3
Burakoff, S.J.4
Schreiber, S.L.5
-
15
-
-
0028899789
-
Phosphorylation of ribosomal protein S6 is inhibitory for autophagy in isolated rat hepatocytes
-
Blommaart, E. F., J. J. Luiken, P. J. Blommaart, G. M. van Woerkom, and A. J. Meijer. 1995. Phosphorylation of ribosomal protein S6 is inhibitory for autophagy in isolated rat hepatocytes. J. Biol. Chem. 270:2320-2326.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 2320-2326
-
-
Blommaart, E.F.1
Luiken, J.J.2
Blommaart, P.J.3
Van Woerkom, G.M.4
Meijer, A.J.5
-
16
-
-
0034961514
-
Insulin-responsive compartments containing GLUT4 in 3T3-L1 and CHO cells: Regulation by amino acid concentrations
-
Bogan, J. S., A. E. McKee, and H. F. Lodish. 2001. Insulin-responsive compartments containing GLUT4 in 3T3-L1 and CHO cells: Regulation by amino acid concentrations. Mol. Cell. Biol. 21:4785-4806.
-
(2001)
Mol. Cell. Biol.
, vol.21
, pp. 4785-4806
-
-
Bogan, J.S.1
McKee, A.E.2
Lodish, H.F.3
-
19
-
-
0029103330
-
Control of p70 s6 kinase by kinase activity of FRAP in vivo
-
Brown, E. J., P. A. Beal, C. T. Keith, J. Chen, T. B. Shin, and S. L. Schreiber. 1995. Control of p70 s6 kinase by kinase activity of FRAP in vivo. Nature 377:441-446.
-
(1995)
Nature
, vol.377
, pp. 441-446
-
-
Brown, E.J.1
Beal, P.A.2
Keith, C.T.3
Chen, J.4
Shin, T.B.5
Schreiber, S.L.6
-
20
-
-
0030881836
-
Phosphorylation of the translational repressor PHAS-I by the mammalian target of rapamycin
-
Brunn, G. J., C. C. Hudson, A. Sekulic, J. M. Williams, H. Hosoi, P. J. Houghton, J. C. Lawrence, Jr., and R. T. Abraham. 1997. Phosphorylation of the translational repressor PHAS-I by the mammalian target of rapamycin. Science 277:99-101.
-
(1997)
Science
, vol.277
, pp. 99-101
-
-
Brunn, G.J.1
Hudson, C.C.2
Sekulic, A.3
Williams, J.M.4
Hosoi, H.5
Houghton, P.J.6
Lawrence J.C., Jr.7
Abraham, R.T.8
-
21
-
-
0032539664
-
RAFT1 phosphorylation of the translational regulators p70 S6 kinase and 4E-BP1
-
Burnett, P. E., R. K. Barrow, N. A. Cohen, S. H. Snyder, and D. M. Sabatini. 1998. RAFT1 phosphorylation of the translational regulators p70 S6 kinase and 4E-BP1. Proc. Natl. Acad. Sci. USA 95:1432-1437.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 1432-1437
-
-
Burnett, P.E.1
Barrow, R.K.2
Cohen, N.A.3
Snyder, S.H.4
Sabatini, D.M.5
-
22
-
-
0027382875
-
Dominant missense mutations in a novel yeast protein related to mammalian phosphatidylinositol 3-kinase and VPS34 abrogate rapamycin cytotoxicity
-
Cafferkey, R., P. R. Young, M. M. McLaughlin, D. J. Bergsma, Y. Koltin, G. M. Sathe, L. Faucette, W. K. Eng, R. K. Johnson, and G. P. Livi. 1993. Dominant missense mutations in a novel yeast protein related to mammalian phosphatidylinositol 3-kinase and VPS34 abrogate rapamycin cytotoxicity. Mol. Cell. Biol. 13:6012-6023.
-
(1993)
Mol. Cell. Biol.
, vol.13
, pp. 6012-6023
-
-
Cafferkey, R.1
Young, P.R.2
McLaughlin, M.M.3
Bergsma, D.J.4
Koltin, Y.5
Sathe, G.M.6
Faucette, L.7
Eng, W.K.8
Johnson, R.K.9
Livi, G.P.10
-
23
-
-
0033489873
-
Glutamine and the immune system
-
Calder, P. C., and P. Yaqoob. 1999. Glutamine and the immune system. Amino Acids 17:227-241.
-
(1999)
Amino Acids
, vol.17
, pp. 227-241
-
-
Calder, P.C.1
Yaqoob, P.2
-
24
-
-
0033573016
-
The TOR signaling cascade regulates gene expression in response to nutrients
-
Cardenas, M. E., N. S. Cutler, M. C. Lorenz, C. J. Di Como, and J. Heitman. 1999. The TOR signaling cascade regulates gene expression in response to nutrients. Genes Dev. 13:3271-3279.
-
(1999)
Genes Dev.
, vol.13
, pp. 3271-3279
-
-
Cardenas, M.E.1
Cutler, N.S.2
Lorenz, M.C.3
Di Como, C.J.4
Heitman, J.5
-
25
-
-
0035816673
-
Phosphorylation regulates the interaction between Gln3p and the nuclear import factor Srp1p
-
Carvalho, J., P. G. Bertram, S. R. Wente, and X. F. Zheng. 2001. Phosphorylation regulates the interaction between Gln3p and the nuclear import factor Srp1p. J. Biol. Chem. 276:25359-25365.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 25359-25365
-
-
Carvalho, J.1
Bertram, P.G.2
Wente, S.R.3
Zheng, X.F.4
-
26
-
-
0035149551
-
Remodeling of yeast genome expression in response to environmental changes
-
Causton, H. C., B. Ren, S. S. Koh, C. T. Harbison, E. Kanin, E. G. Jennings, T. I. Lee, H. L. True, E. S. Lander, and R. A. Young. 2001. Remodeling of yeast genome expression in response to environmental changes. Mol. Biol. Cell 12:323-337.
-
(2001)
Mol. Biol. Cell
, vol.12
, pp. 323-337
-
-
Causton, H.C.1
Ren, B.2
Koh, S.S.3
Harbison, C.T.4
Kanin, E.5
Jennings, E.G.6
Lee, T.I.7
True, H.L.8
Lander, E.S.9
Young, R.A.10
-
27
-
-
0032577919
-
Alpha 4 associates with protein phosphatases 2A, 4, and 6
-
Chen, J., R. T. Peterson, and S. L. Schreiber. 1998. Alpha 4 associates with protein phosphatases 2A, 4, and 6. Biochem. Biophys. Res. Commun. 247:827-832.
-
(1998)
Biochem. Biophys. Res. Commun.
, vol.247
, pp. 827-832
-
-
Chen, J.1
Peterson, R.T.2
Schreiber, S.L.3
-
28
-
-
0029055145
-
Identification of an 11-kDa FKBP12-rapamycin-binding domain within the 289-kDa FKBP12-rapamycin-associated protein and characterization of a critical serine residue
-
Chen, J., X. F. Zheng, E. J. Brown, and S. L. Schreiber. 1995. Identification of an 11-kDa FKBP12-rapamycin-binding domain within the 289-kDa FKBP12-rapamycin-associated protein and characterization of a critical serine residue. Proc. Natl. Acad. Sci. USA 92:4947-4951.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 4947-4951
-
-
Chen, J.1
Zheng, X.F.2
Brown, E.J.3
Schreiber, S.L.4
-
29
-
-
0028598672
-
RAPTI, a mammalian homolog of yeast Tor, interacts with the FKBP12/rapamycin complex
-
Chiu, M. I., H. Katz, and V. Berlin. 1994. RAPTI, a mammalian homolog of yeast Tor, interacts with the FKBP12/rapamycin complex. Proc. Natl. Acad. Sci. USA 91:12574-12578.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 12574-12578
-
-
Chiu, M.I.1
Katz, H.2
Berlin, V.3
-
30
-
-
0029842109
-
Structure of the FKBP12-rapamycin complex interacting with the binding domain of human FRAP
-
Choi, J., J. Chen, S. L. Schreiber, and J. Clardy. 1996. Structure of the FKBP12-rapamycin complex interacting with the binding domain of human FRAP. Science 273:239-242.
-
(1996)
Science
, vol.273
, pp. 239-242
-
-
Choi, J.1
Chen, J.2
Schreiber, S.L.3
Clardy, J.4
-
31
-
-
0026659046
-
Rapamycin-FKBP specifically blocks growth-dependent activation of and signaling by the 70 kd S6 protein kinases
-
Chung, J., C. J. Kuo, G. R. Crabtree, and J. Blenis. 1992. Rapamycin-FKBP specifically blocks growth-dependent activation of and signaling by the 70 kd S6 protein kinases. Cell 69:1227-1236.
-
(1992)
Cell
, vol.69
, pp. 1227-1236
-
-
Chung, J.1
Kuo, C.J.2
Crabtree, G.R.3
Blenis, J.4
-
32
-
-
0000189281
-
Cellular differentiation in the kidneys of newborn mice studied with the electron microscope
-
Clark, S. L. 1957. Cellular differentiation in the kidneys of newborn mice studied with the electron microscope. J. Biophys. Biochem. Cytol. 3:349-360.
-
(1957)
J. Biophys. Biochem. Cytol.
, vol.3
, pp. 349-360
-
-
Clark, S.L.1
-
33
-
-
0034044544
-
Eap1p, a novel eukaryotic translation initiation factor 4E-associated protein in Saccharomyces cerevisiae
-
Cosentino, G. P., T. Schmelzle, A. Haghighat, S. B. Helliwell, M. N. Hall, and N. Sonenberg. 2000. Eap1p, a novel eukaryotic translation initiation factor 4E-associated protein in Saccharomyces cerevisiae. Mol. Cell. Biol. 20:4604-4613.
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 4604-4613
-
-
Cosentino, G.P.1
Schmelzle, T.2
Haghighat, A.3
Helliwell, S.B.4
Hall, M.N.5
Sonenberg, N.6
-
34
-
-
0035860714
-
The GATA transcription factors GLN3 and GAT1 link TOR to salt stress in Saccharomyces cerevisiae
-
Crespo, J. L., K. Daicho, T. Ushimaru, and M. N. Hall. 2001. The GATA transcription factors GLN3 and GAT1 link TOR to salt stress in Saccharomyces cerevisiae. J. Biol. Chem. 276:34441-34444.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 34441-34444
-
-
Crespo, J.L.1
Daicho, K.2
Ushimaru, T.3
Hall, M.N.4
-
35
-
-
0037076314
-
The TOR-controlled transcription activators GLN3, RTG1 and RTG3 are regulated in response to intracellular levels of glutamine
-
Crespo, J. L., T. Powers, B. Fowler, and M. N. Hall. 2002. The TOR-controlled transcription activators GLN3, RTG1 and RTG3 are regulated in response to intracellular levels of glutamine. Proc. Natl. Acad. Sci. USA 99:6784-6789.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 6784-6789
-
-
Crespo, J.L.1
Powers, T.2
Fowler, B.3
Hall, M.N.4
-
36
-
-
0033043180
-
Rapamycin antifungal action is mediated via conserved complexes with FKBP12 and TOR kinase homologs in Cryptococcus neoformans
-
Cruz, M. C., L. M. Cavallo, J. M. Gorlach, G. Cox, J. R. Perfect, M. E. Cardenas, and J. Heitman. 1999. Rapamycin antifungal action is mediated via conserved complexes with FKBP12 and TOR kinase homologs in Cryptococcus neoformans. Mol. Cell. Biol. 19:4101-4112.
-
(1999)
Mol. Cell. Biol.
, vol.19
, pp. 4101-4112
-
-
Cruz, M.C.1
Cavallo, L.M.2
Gorlach, J.M.3
Cox, G.4
Perfect, J.R.5
Cardenas, M.E.6
Heitman, J.7
-
37
-
-
0034774478
-
Rapamycin and less immunosuppressive analogs are toxic to Candida albicans and Cryptococcus neoformans via FKBP12-dependent inhibition of TOR
-
Cruz, M. C., A. L. Goldstein, J. Blankenship, M. Del Poeta, J. R. Perfect, J. H. McCusker, Y. L. Bennani, M. E. Cardenas, and J. Heitman. 2001. Rapamycin and less immunosuppressive analogs are toxic to Candida albicans and Cryptococcus neoformans via FKBP12-dependent inhibition of TOR. Antimicrob. Agents Chemother. 45:3162-3170.
-
(2001)
Antimicrob. Agents Chemother.
, vol.45
, pp. 3162-3170
-
-
Cruz, M.C.1
Goldstein, A.L.2
Blankenship, J.3
Del Poeta, M.4
Perfect, J.R.5
McCusker, J.H.6
Bennani, Y.L.7
Cardenas, M.E.8
Heitman, J.9
-
38
-
-
0035664839
-
The TOR signal transduction cascade controls cellular differentiation in response to nutrients
-
Cutler, N. S., X. Pan, J. Heitman, and M. E. Cardenas. 2001. The TOR signal transduction cascade controls cellular differentiation in response to nutrients. Mol. Biol. Cell 12:4103-4113.
-
(2001)
Mol. Biol. Cell
, vol.12
, pp. 4103-4113
-
-
Cutler, N.S.1
Pan, X.2
Heitman, J.3
Cardenas, M.E.4
-
40
-
-
0035941266
-
The Npr1 kinase controls biosynthetic and endocytic sorting of the yeast Gap1 permease
-
De Craene, J. O., O. Soetens, and B. Andre. 2001. The Npr1 kinase controls biosynthetic and endocytic sorting of the yeast Gap1 permease. J. Biol. Chem. 276:43939-43948.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 43939-43948
-
-
De Craene, J.O.1
Soetens, O.2
Andre, B.3
-
41
-
-
0032999830
-
Target of rapamycin (TOR): Balancing the opposing forces of protein synthesis and degradation
-
Dennis, P. B., S. Fumagalli, and G. Thomas. 1999. Target of rapamycin (TOR): Balancing the opposing forces of protein synthesis and degradation. Curr. Opin. Genet. Dev. 9:49-54.
-
(1999)
Curr. Opin. Genet. Dev.
, vol.9
, pp. 49-54
-
-
Dennis, P.B.1
Fumagalli, S.2
Thomas, G.3
-
42
-
-
0035798097
-
Mammalian TOR: A homeostatic ATP sensor
-
Dennis, P. B., A. Jaeschke, M. Saitoh, B. Fowler, S. C. Kozma, and G. Thomas. 2001. Mammalian TOR: A homeostatic ATP sensor. Science 294: 1102-1105.
-
(2001)
Science
, vol.294
, pp. 1102-1105
-
-
Dennis, P.B.1
Jaeschke, A.2
Saitoh, M.3
Fowler, B.4
Kozma, S.C.5
Thomas, G.6
-
43
-
-
0029828590
-
s6k phosphorylation sites, T-229 and T-389, are differentially regulated by rapamycin-insensitive kinase kinases
-
s6k phosphorylation sites, T-229 and T-389, are differentially regulated by rapamycin-insensitive kinase kinases. Mol. Cell. Biol. 16:6242-6251.
-
(1996)
Mol. Cell. Biol.
, vol.16
, pp. 6242-6251
-
-
Dennis, P.B.1
Pullen, N.2
Kozma, S.C.3
Thomas, G.4
-
44
-
-
0029808294
-
Nutrients, via the Tor proteins, stimulate the association of Tap42 with type 2A phosphatases
-
Di Como, C. J., and K. T. Arndt. 1996. Nutrients, via the Tor proteins, stimulate the association of Tap42 with type 2A phosphatases. Genes Dev. 10:1904-1916.
-
(1996)
Genes Dev.
, vol.10
, pp. 1904-1916
-
-
Di Como, C.J.1
Arndt, K.T.2
-
45
-
-
0037022532
-
Mks1 in concert with TOR signaling negatively regulates RTG target gene expression in S. cerevisiae
-
Dilova, I., C. Y. Chen, and T. Powers. 2002. Mks1 in concert with TOR signaling negatively regulates RTG target gene expression in S. cerevisiae. Curr. Biol. 12:389-395.
-
(2002)
Curr. Biol.
, vol.12
, pp. 389-395
-
-
Dilova, I.1
Chen, C.Y.2
Powers, T.3
-
46
-
-
0035976615
-
Phosphatidic acid-mediated mitogenic activation of mTOR signaling
-
Fang, Y., M. Vilella-Bach, R. Bachmann, A. Flanigan, and J. Chen. 2001. Phosphatidic acid-mediated mitogenic activation of mTOR signaling. Science 294:1942-1945.
-
(2001)
Science
, vol.294
, pp. 1942-1945
-
-
Fang, Y.1
Vilella-Bach, M.2
Bachmann, R.3
Flanigan, A.4
Chen, J.5
-
49
-
-
0035162698
-
Genomic expression responses to DNA-damaging agents and the regulatory role of the yeast ATR homolog Mec1p
-
Gasch, A. P., M. Huang, S. Metzner, D. Botstein, S. J. Elledge, and P. O. Brown. 2001. Genomic expression responses to DNA-damaging agents and the regulatory role of the yeast ATR homolog Mec1p. Mol. Biol. Cell 12:2987-3003.
-
(2001)
Mol. Biol. Cell
, vol.12
, pp. 2987-3003
-
-
Gasch, A.P.1
Huang, M.2
Metzner, S.3
Botstein, D.4
Elledge, S.J.5
Brown, P.O.6
-
50
-
-
0033153166
-
Regulation of 4E-BP1 phosphorylation: A novel two-step mechanism
-
Gingras, A. C., S. P. Gygi, B. Raught, R. D. Polakiewicz, R. T. Abraham, M. F. Hoekstra, R. Aebersold, and N. Sonenberg. 1999. Regulation of 4E-BP1 phosphorylation: A novel two-step mechanism. Genes Dev. 13: 1422-1437.
-
(1999)
Genes Dev.
, vol.13
, pp. 1422-1437
-
-
Gingras, A.C.1
Gygi, S.P.2
Raught, B.3
Polakiewicz, R.D.4
Abraham, R.T.5
Hoekstra, M.F.6
Aebersold, R.7
Sonenberg, N.8
-
51
-
-
0035498939
-
Hierarchical phosphorylation of the translation inhibitor 4E-BP1
-
Gingras, A. C., B. Raught, S. P. Gygi, A. Niedzwiecka, M. Miron, S. K. Burley, R. D. Polakiewicz, A. Wyslouch-Cieszynska, R. Aebersold, and N. Sonenberg. 2001. Hierarchical phosphorylation of the translation inhibitor 4E-BP1. Genes Dev. 15:2852-2864.
-
(2001)
Genes Dev.
, vol.15
, pp. 2852-2864
-
-
Gingras, A.C.1
Raught, B.2
Gygi, S.P.3
Niedzwiecka, A.4
Miron, M.5
Burley, S.K.6
Polakiewicz, R.D.7
Wyslouch-Cieszynska, A.8
Aebersold, R.9
Sonenberg, N.10
-
52
-
-
0035312747
-
Regulation of translation initiation by FRAP/mTOR
-
Gingras, A. C., B. Raught, and N. Sonenberg. 2001. Regulation of translation initiation by FRAP/mTOR. Genes Dev. 15:807-826.
-
(2001)
Genes Dev.
, vol.15
, pp. 807-826
-
-
Gingras, A.C.1
Raught, B.2
Sonenberg, N.3
-
53
-
-
0032518996
-
Nuclear localization of the C2H2 zinc finger protein Msn2p is regulated by stress and protein kinase A activity
-
Gorner, W., E. Durchschlag, M. T. Martinez-Pastor, F. Estruch, G. Ammerer, B. Hamilton, H. Ruis, and C. Schuller. 1998. Nuclear localization of the C2H2 zinc finger protein Msn2p is regulated by stress and protein kinase A activity. Genes Dev. 12:586-597.
-
(1998)
Genes Dev.
, vol.12
, pp. 586-597
-
-
Gorner, W.1
Durchschlag, E.2
Martinez-Pastor, M.T.3
Estruch, F.4
Ammerer, G.5
Hamilton, B.6
Ruis, H.7
Schuller, C.8
-
54
-
-
0020774482
-
Inactivation-reactivation process and repression of permease formation regulate several ammonia-sensitive permeases in the yeast Saccharomyces cerevisiae
-
Grenson, M. 1983. Inactivation-reactivation process and repression of permease formation regulate several ammonia-sensitive permeases in the yeast Saccharomyces cerevisiae. Eur. J. Biochem. 133:135-139.
-
(1983)
Eur. J. Biochem.
, vol.133
, pp. 135-139
-
-
Grenson, M.1
-
55
-
-
0020773011
-
Study of the positive control of the general amino-acid permease and other ammonia-sensitive uptake systems by the product of the NPR1 gene in the yeast Saccharomyces cerevisiae
-
Grenson, M. 1983. Study of the positive control of the general amino-acid permease and other ammonia-sensitive uptake systems by the product of the NPR1 gene in the yeast Saccharomyces cerevisiae. Eur. J. Biochem. 133:141-144.
-
(1983)
Eur. J. Biochem.
, vol.133
, pp. 141-144
-
-
Grenson, M.1
-
56
-
-
0033534405
-
The structure of the protein phosphatase 2A PR65/A subunit reveals the conformation of its 15 tandemly repeated HEAT motifs
-
Groves, M. R., N. Hanlon, P. Turowski, B. A. Hemmings, and D. Barford. 1999. The structure of the protein phosphatase 2A PR65/A subunit reveals the conformation of its 15 tandemly repeated HEAT motifs. Cell 96:99110.
-
(1999)
Cell
, vol.96
, pp. 99110
-
-
Groves, M.R.1
Hanlon, N.2
Turowski, P.3
Hemmings, B.A.4
Barford, D.5
-
57
-
-
0036174289
-
Rapamycin inhibits primary and metastatic tumor growth by antiangiogenesis: Involvement of vascular endothelial growth factor
-
Guba, M., P. von Breltenbuch, M. Steinbauer, G. Koehl, S. Flegel, M. Hornung, C. J. Bruns, C. Zuelke, S. Farkas, M. Anthuber, K. W. Jauch, and E. K. Geissler. 2002. Rapamycin inhibits primary and metastatic tumor growth by antiangiogenesis: Involvement of vascular endothelial growth factor. Nat. Med. 8:128-135.
-
(2002)
Nat. Med.
, vol.8
, pp. 128-135
-
-
Guba, M.1
Von Breltenbuch, P.2
Steinbauer, M.3
Koehl, G.4
Flegel, S.5
Hornung, M.6
Bruns, C.J.7
Zuelke, C.8
Farkas, S.9
Anthuber, M.10
Jauch, K.W.11
Geissler, E.K.12
-
58
-
-
0030716488
-
Regulation of eIF-4E BP1 phosphorylation by mTOR
-
Hara, K., K. Yonezawa, M. T. Kozlowski, T. Sugimoto, K. Andrabi, Q. P. Weng, M. Kasuga, I. Nishimoto, and J. Avruch. 1997. Regulation of eIF-4E BP1 phosphorylation by mTOR. J. Biol. Chem. 272:26457-26463.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 26457-26463
-
-
Hara, K.1
Yonezawa, K.2
Kozlowski, M.T.3
Sugimoto, T.4
Andrabi, K.5
Weng, Q.P.6
Kasuga, M.7
Nishimoto, I.8
Avruch, J.9
-
59
-
-
0032486268
-
Amino acid sufficiency and mTOR regulate p70 S6 kinase and eIF-4E BP1 through a common effector mechanism
-
Hara, K., K. Yonezawa, Q. P. Weng, M. T. Kozlowski, C. Belham, and J. Avruch. 1998. Amino acid sufficiency and mTOR regulate p70 S6 kinase and eIF-4E BP1 through a common effector mechanism. J. Biol Chem. 273:14484-14494.
-
(1998)
J. Biol Chem.
, vol.273
, pp. 14484-14494
-
-
Hara, K.1
Yonezawa, K.2
Weng, Q.P.3
Kozlowski, M.T.4
Belham, C.5
Avruch, J.6
-
60
-
-
0033592983
-
Rapamycin-modulated transcription defines the subset of nutrient-sensitive signaling pathways directly controlled by the Tor proteins
-
Hardwick, J. S., F. G. Kuruvilla, J. K. Tong, A. F. Shamji, and S. L. Schreiber. 1999. Rapamycin-modulated transcription defines the subset of nutrient-sensitive signaling pathways directly controlled by the Tor proteins. Proc. Natl. Acad. Sci. USA 96:14866-14870.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 14866-14870
-
-
Hardwick, J.S.1
Kuruvilla, F.G.2
Tong, J.K.3
Shamji, A.F.4
Schreiber, S.L.5
-
61
-
-
0033213260
-
The Arabidopsis homolog of yeast TAP42 and mammalian alpha4 binds to the catalytic subunit of protein phosphatase 2A and is induced by chilling
-
Harris, D. M., T. L. Myrick, and S. J. Rundle. 1999. The Arabidopsis homolog of yeast TAP42 and mammalian alpha4 binds to the catalytic subunit of protein phosphatase 2A and is induced by chilling. Plant Physiol. 121:609-617.
-
(1999)
Plant Physiol.
, vol.121
, pp. 609-617
-
-
Harris, D.M.1
Myrick, T.L.2
Rundle, S.J.3
-
62
-
-
0026857926
-
Proline isomerases at the crossroads of protein folding, signal transduction, and immunosuppression
-
Heitman, J., N. R. Mowa, and M. N. Hall. 1992. Proline isomerases at the crossroads of protein folding, signal transduction, and immunosuppression. New Biol. 4:448-460.
-
(1992)
New Biol.
, vol.4
, pp. 448-460
-
-
Heitman, J.1
Mowa, N.R.2
Hall, M.N.3
-
63
-
-
0025776523
-
Targets for cell cycle arrest by the immunosuppressant rapamycin in yeast
-
Heitman, J., N. R. Movva, and M. N. Hall. 1991. Targets for cell cycle arrest by the immunosuppressant rapamycin in yeast. Science 253:905-909.
-
(1991)
Science
, vol.253
, pp. 905-909
-
-
Heitman, J.1
Movva, N.R.2
Hall, M.N.3
-
64
-
-
0026012156
-
FK 506-binding protein proline rotamase is a target for the immunosuppressive agent FK 506 in Saccharomyces cerevisiae
-
Heitman, J., N. R. Movva, P. C. Hiestand, and M. N. Hall. 1991. FK 506-binding protein proline rotamase is a target for the immunosuppressive agent FK 506 in Saccharomyces cerevisiae. Proc. Natl. Acad. Sci. USA 88:1948-1952.
-
(1991)
Proc. Natl. Acad. Sci. USA
, vol.88
, pp. 1948-1952
-
-
Heitman, J.1
Movva, N.R.2
Hiestand, P.C.3
Hall, M.N.4
-
65
-
-
0031882240
-
TOR2 is part of two related signaling pathways coordinating cell growth in Saccharomyces cerevisiae
-
Helliwell, S. B., I. Howald, N. Barbet, and M. N. Hall. 1998. TOR2 is part of two related signaling pathways coordinating cell growth in Saccharomyces cerevisiae. Genetics 148:99-112.
-
(1998)
Genetics
, vol.148
, pp. 99-112
-
-
Helliwell, S.B.1
Howald, I.2
Barbet, N.3
Hall, M.N.4
-
66
-
-
0032488042
-
The Rho1 effector Pkc1, but not Bni1, mediates signalling from Tor2 to the actin cytoskeleton
-
Helliwell, S. B., A. Schmidt, V. Ohya, and M. N. Hall. 1998. The Rho1 effector Pkc1, but not Bni1, mediates signalling from Tor2 to the actin cytoskeleton. Curr. Biol. 8:1211-1214.
-
(1998)
Curr. Biol.
, vol.8
, pp. 1211-1214
-
-
Helliwell, S.B.1
Schmidt, A.2
Ohya, V.3
Hall, M.N.4
-
67
-
-
0028137771
-
TOR1 and TOR2 are structurally and functionally similar but not identical phosphatidylinositol kinase homologues in yeast
-
Halliwell, S. B., P. Wagner, J. Kunz, M. Deuter-Reinhard, R. Henriquez, and M. N. Hall. 1994. TOR1 and TOR2 are structurally and functionally similar but not identical phosphatidylinositol kinase homologues in yeast. Mol. Biol. Cell 5:105-118.
-
(1994)
Mol. Biol. Cell
, vol.5
, pp. 105-118
-
-
Halliwell, S.B.1
Wagner, P.2
Kunz, J.3
Deuter-Reinhard, M.4
Henriquez, R.5
Hall, M.N.6
-
68
-
-
0025275038
-
alpha- and beta-forms of the 65-kDa subunit of protein phosphatase 2A have a similar 39 amino acid repeating structure
-
Hemmings, B. A., C. Adams-Pearson, F. Maurer, P. Muller, J. Goris, W. Merlevede, J. Hofsteenge, and S. R. Stone. 1990. alpha- and beta-forms of the 65-kDa subunit of protein phosphatase 2A have a similar 39 amino acid repeating structure. Biochemistry. 29:3166-3173.
-
(1990)
Biochemistry
, vol.29
, pp. 3166-3173
-
-
Hemmings, B.A.1
Adams-Pearson, C.2
Maurer, F.3
Muller, P.4
Goris, J.5
Merlevede, W.6
Hofsteenge, J.7
Stone, S.R.8
-
69
-
-
0000091608
-
The pathway and mechanism of initiation of protein synthesis
-
N. Sonenberg, J. W. B. Hershey, and M. B. Mathews (ed.), Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y
-
Hershey, J. W. B., and W. C. Merrick. 2000. The pathway and mechanism of initiation of protein synthesis, p. 33-88. In N. Sonenberg, J. W. B. Hershey, and M. B. Mathews (ed.), Translational Control of Gene Expression. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
-
(2000)
Translational Control of Gene Expression
, pp. 33-88
-
-
Hershey, J.W.B.1
Merrick, W.C.2
-
70
-
-
0034722888
-
The rapamycin-sensitive signal transduction pathway as a target for cancer therapy
-
Hidalgo, M., and E. K. Rowinsky. 2000. The rapamycin-sensitive signal transduction pathway as a target for cancer therapy. Oncogene 19:6680-6686.
-
(2000)
Oncogene
, vol.19
, pp. 6680-6686
-
-
Hidalgo, M.1
Rowinsky, E.K.2
-
71
-
-
0002470681
-
Mechanism and regulation of initiator methionyl-tRNA binding to ribosomes
-
N. Sonenberg, J. W. B. Hershey, and M. B. Mathews (ed.), Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y
-
Hinnebusch, A. G. 2000. Mechanism and regulation of initiator methionyl-tRNA binding to ribosomes, p. 185-243. In N. Sonenberg, J. W. B. Hershey, and M. B. Mathews (ed.), Translational Control of Gene Expression. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
-
(2000)
Translational Control of Gene Expression
, pp. 185-243
-
-
Hinnebusch, A.G.1
-
72
-
-
0030803256
-
Translational regulation of yeast GCN4. A window on factors that control initiator-tRNA binding to the ribosome
-
Hinnebusch, A. G. 1997. Translational regulation of yeast GCN4. A window on factors that control initiator-tRNA binding to the ribosome. J. Biol. Chem. 272:21661-21664.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 21661-21664
-
-
Hinnebusch, A.G.1
-
73
-
-
0031755688
-
Studies on the mechanism of resistance to rapamycin in human cancer cells
-
Hosoi, H., M. B. Dilling, L. N. Liu, M. K. Danks, T. Shikata, A. Sekulic, R. T. Abraham, J. C. Lawrence, Jr., and P. J. Houghton. 1998. Studies on the mechanism of resistance to rapamycin in human cancer cells. Mol. Pharmacol. 54:815-824.
-
(1998)
Mol. Pharmacol.
, vol.54
, pp. 815-824
-
-
Hosoi, H.1
Dilling, M.B.2
Liu, L.N.3
Danks, M.K.4
Shikata, T.5
Sekulic, A.6
Abraham, R.T.7
Lawrence J.C., Jr.8
Houghton, P.J.9
-
74
-
-
0029792380
-
Coordinated regulation of gene expression by the cell cycle transcription factor Swi4 and the protein kinase C MAP kinase pathway for yeast cell integrity
-
Igual, J. C., A. L. Johnson, and L. H. Johnston. 1996. Coordinated regulation of gene expression by the cell cycle transcription factor Swi4 and the protein kinase C MAP kinase pathway for yeast cell integrity. EMBO J. 15:5001-5013.
-
(1996)
EMBO J.
, vol.15
, pp. 5001-5013
-
-
Igual, J.C.1
Johnson, A.L.2
Johnston, L.H.3
-
75
-
-
0033526844
-
L-Asparaginase inhibits the rapamycin-targeted signaling pathway
-
Iiboshi, Y., P. J. Papst, S. P. Hunger, and N. Terada. 1999. L-Asparaginase inhibits the rapamycin-targeted signaling pathway. Biochem. Biophys. Res. Commun. 260:534-539.
-
(1999)
Biochem. Biophys. Res. Commun.
, vol.260
, pp. 534-539
-
-
Iiboshi, Y.1
Papst, P.J.2
Hunger, S.P.3
Terada, N.4
-
76
-
-
0033534686
-
Amino acid-dependent control of p70(s6k). Involvement of tRNA aminoacylation in the regulation
-
Iiboshi, Y., P. J. Papst, H. Kawasome, H. Hosoi, R. T. Abraham, P. J. Houghton, and N. Terada. 1999. Amino acid-dependent control of p70(s6k). Involvement of tRNA aminoacylation in the regulation. J. Biol. Chem. 274:1092-1099.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 1092-1099
-
-
Iiboshi, Y.1
Papst, P.J.2
Kawasome, H.3
Hosoi, H.4
Abraham, R.T.5
Houghton, P.J.6
Terada, N.7
-
77
-
-
0032528434
-
Ig receptor binding protein 1 (alpha4) is associated with a rapamycin-sensitive signal transduction in lymphocytes through direct binding to the catalytic subunit of protein phosphatase 2A
-
Inui, S., H. Sanjo, K. Maeda, H. Yamamoto, E. Miyamoto, and N. Sakaguchi. 1998. Ig receptor binding protein 1 (alpha4) is associated with a rapamycin-sensitive signal transduction in lymphocytes through direct binding to the catalytic subunit of protein phosphatase 2A. Blood 92:539-546.
-
(1998)
Blood
, vol.92
, pp. 539-546
-
-
Inui, S.1
Sanjo, H.2
Maeda, K.3
Yamamoto, H.4
Miyamoto, E.5
Sakaguchi, N.6
-
78
-
-
0033607531
-
Immunopurified mammalian target of rapamycin phosphorylates and activates p70 S6 kinase alpha in vitro
-
Isotani, S., K. Hara, C. Tokunaga, H. Inoue, J. Avruch, and K. Yonezawa. 1999. Immunopurified mammalian target of rapamycin phosphorylates and activates p70 S6 kinase alpha in vitro. J. Biol. Chem. 274:34493-34498.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 34493-34498
-
-
Isotani, S.1
Hara, K.2
Tokunaga, C.3
Inoue, H.4
Avruch, J.5
Yonezawa, K.6
-
79
-
-
0035930339
-
TIP41 interacts with TAP42 and negatively regulates the TOR signaling pathway
-
Jacinto, E., B. Guo, K. T. Arndt, T. Schmelzle, and M. N. Hall. 2001. TIP41 interacts with TAP42 and negatively regulates the TOR signaling pathway. Mol. Cell 8:1017-1026.
-
(2001)
Mol. Cell
, vol.8
, pp. 1017-1026
-
-
Jacinto, E.1
Guo, B.2
Arndt, K.T.3
Schmelzle, T.4
Hall, M.N.5
-
80
-
-
0030915898
-
Rapamycin suppresses 5′TOP mRNA translation through inhibition of p70s6k
-
Jefferies, H. B., S. Fumagalli, P. B. Dennis, C. Reinhard, R. B. Pearson, and G. Thomas. 1997. Rapamycin suppresses 5′TOP mRNA translation through inhibition of p70s6k. EMBO J. 16:3693-3704.
-
(1997)
EMBO J.
, vol.16
, pp. 3693-3704
-
-
Jefferies, H.B.1
Fumagalli, S.2
Dennis, P.B.3
Reinhard, C.4
Pearson, R.B.5
Thomas, G.6
-
81
-
-
0033577745
-
Tor proteins and protein phosphatase 2A reciprocally regulate Tap42 in controlling cell growth in yeast
-
Jiang, Y., and J. R. Broach. 1999. Tor proteins and protein phosphatase 2A reciprocally regulate Tap42 in controlling cell growth in yeast. EMBO J. 18:2782-2792.
-
(1999)
EMBO J.
, vol.18
, pp. 2782-2792
-
-
Jiang, Y.1
Broach, J.R.2
-
82
-
-
0023122945
-
Phosphorylation of the Saccharomyces cerevisiae equivalent of ribosomal protein S6 has no detectable effect on growth
-
Johnson, S. P., and J. R. Warner. 1987. Phosphorylation of the Saccharomyces cerevisiae equivalent of ribosomal protein S6 has no detectable effect on growth. Mol. Cell. Biol. 7:1338-1345.
-
(1987)
Mol. Cell. Biol.
, vol.7
, pp. 1338-1345
-
-
Johnson, S.P.1
Warner, J.R.2
-
83
-
-
0034329418
-
LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing
-
Kabeya, Y., N. Mizushima, T. Ueno, A. Yamamoto, T. Kirisako, T. Noda, E. Kominami, Y. Ohsumi, and T. Yoshimori. 2000. LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing. EMBO J. 19:5720-5728.
-
(2000)
EMBO J.
, vol.19
, pp. 5720-5728
-
-
Kabeya, Y.1
Mizushima, N.2
Ueno, T.3
Yamamoto, A.4
Kirisako, T.5
Noda, T.6
Kominami, E.7
Ohsumi, Y.8
Yoshimori, T.9
-
84
-
-
0020586302
-
Enzyme-induced asparagine and glutamine depletion and immune system function
-
Kafkewitz, D., and A. Bendich. 1983. Enzyme-induced asparagine and glutamine depletion and immune system function. Am. J. Clin. Nutr. 37:1025-1030.
-
(1983)
Am. J. Clin. Nutr.
, vol.37
, pp. 1025-1030
-
-
Kafkewitz, D.1
Bendich, A.2
-
85
-
-
0034683568
-
Tor-mediated induction of autophagy via an Apg1 protein kinase complex
-
Kamada, Y., T. Funakoshi, T. Shintani, K. Nagano, M. Ohsumi, and Y. Ohsumi. 2000. Tor-mediated induction of autophagy via an Apg1 protein kinase complex. J. Cell Biol. 150:1507-1513.
-
(2000)
J. Cell Biol.
, vol.150
, pp. 1507-1513
-
-
Kamada, Y.1
Funakoshi, T.2
Shintani, T.3
Nagano, K.4
Ohsumi, M.5
Ohsumi, Y.6
-
86
-
-
0035006616
-
Fission yeast torl functions in response to various stresses including nitrogen starvation, high osmolarity, and high temperature
-
Kawai, M., A. Nakashima, M. Ueno, T. Ushimaru, K. Aiba, H. Doi, and M. Uritani. 2001. Fission yeast torl functions in response to various stresses including nitrogen starvation, high osmolarity, and high temperature. Curr. Genet. 39:166-174.
-
(2001)
Curr. Genet.
, vol.39
, pp. 166-174
-
-
Kawai, M.1
Nakashima, A.2
Ueno, M.3
Ushimaru, T.4
Aiba, K.5
Doi, H.6
Uritani, M.7
-
87
-
-
0028800996
-
PIK-related kinases: DNA repair, recombination, and cell cycle checkpoints
-
Keith, C. T., and S. L. Schreiber. 1995. PIK-related kinases: DNA repair, recombination, and cell cycle checkpoints. Science 270:50-51.
-
(1995)
Science
, vol.270
, pp. 50-51
-
-
Keith, C.T.1
Schreiber, S.L.2
-
88
-
-
0028012738
-
Amino acid-regulated gene expression in eukaryotic cells
-
Kilberg, M. S., R. G. Hutson, and R. O. Laine. 1994. Amino acid-regulated gene expression in eukaryotic cells. FASEB J. 8:13-19.
-
(1994)
FASEB J.
, vol.8
, pp. 13-19
-
-
Kilberg, M.S.1
Hutson, R.G.2
Laine, R.O.3
-
89
-
-
0033280667
-
Vacuolar import of proteins and organelles from the cytoplasm
-
Klionsky, D. J., and Y. Ohsumi. 1999. Vacuolar import of proteins and organelles from the cytoplasm. Annu. Rev. Cell Dev. Biol. 15:1-32.
-
(1999)
Annu. Rev. Cell Dev. Biol.
, vol.15
, pp. 1-32
-
-
Klionsky, D.J.1
Ohsumi, Y.2
-
90
-
-
0026092585
-
Rapamycin sensitivity in Saccharomyces cerevisiae is mediated by a peptidyl-prolyl cis-trans isomerase related to human FK506-binding protein
-
Koltin, Y., L. Faucette, D. J. Bergsma, M. A. Levy, R. Cafferkey, P. L. Koser, R. K. Johnson, and G. P. Livi. 1991. Rapamycin sensitivity in Saccharomyces cerevisiae is mediated by a peptidyl-prolyl cis-trans isomerase related to human FK506-binding protein. Mol. Cell. Biol. 11:1718-1723.
-
(1991)
Mol. Cell. Biol.
, vol.11
, pp. 1718-1723
-
-
Koltin, Y.1
Faucette, L.2
Bergsma, D.J.3
Levy, M.A.4
Cafferkey, R.5
Koser, P.L.6
Johnson, R.K.7
Livi, G.P.8
-
91
-
-
0034645038
-
Mechanism of metabolic control. Target of rapamycin signaling links nitrogen quality to the activity of the Rtgl and Rtg3 transcription factors
-
Komeili, A., K. P. Wedaman, E. K. O'Shea, and T. Powers. 2000. Mechanism of metabolic control. Target of rapamycin signaling links nitrogen quality to the activity of the Rtgl and Rtg3 transcription factors. J. Cell Biol. 151:863-878.
-
(2000)
J. Cell Biol.
, vol.151
, pp. 863-878
-
-
Komeili, A.1
Wedaman, K.P.2
O'Shea, E.K.3
Powers, T.4
-
93
-
-
0034711280
-
HEAT repeats mediate plasma membrane localization of Tor2p in yeast
-
Kunz, J., U. Schneider, I. Howald, A. Schmidt, and M. N. Hall. 2000. HEAT repeats mediate plasma membrane localization of Tor2p in yeast. J. Biol. Chem. 275:37011-37020.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 37011-37020
-
-
Kunz, J.1
Schneider, U.2
Howald, I.3
Schmidt, A.4
Hall, M.N.5
-
94
-
-
0026721092
-
Rapamycin selectively inhibits interleukin-2 activation of p70 S6 kinase
-
Kuo, C. J., J. Chung, D. F. Fiorentino, W. M. Flanagan, J. Blenis, and G. R. Crabtree. 1992. Rapamycin selectively inhibits interleukin-2 activation of p70 S6 kinase. Nature 358:70-73.
-
(1992)
Nature
, vol.358
, pp. 70-73
-
-
Kuo, C.J.1
Chung, J.2
Fiorentino, D.F.3
Flanagan, W.M.4
Blenis, J.5
Crabtree, G.R.6
-
95
-
-
0035912781
-
Carbon- and nitrogen-quality signaling to translation are mediated by distinct GATA-type transcription factors
-
Kuruvilla, F. G., A. F. Shamji, and S. L. Schreiber. 2001. Carbon- and nitrogen-quality signaling to translation are mediated by distinct GATA-type transcription factors. Proc. Natl. Acad. Sci. USA 98:7283-7288.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 7283-7288
-
-
Kuruvilla, F.G.1
Shamji, A.F.2
Schreiber, S.L.3
-
96
-
-
0029845130
-
Okadaic acid induces cellular hypertrophy in AKR-2B fibroblasts: Involvement of the p70S6 kinase in the onset of protein and rRNA synthesis
-
Leicht, M., A. Simm, G. Bertsch, and J. Hoppe. 1996. Okadaic acid induces cellular hypertrophy in AKR-2B fibroblasts: Involvement of the p70S6 kinase in the onset of protein and rRNA synthesis. Cell Growth Differ. 7:1199-1209.
-
(1996)
Cell Growth Differ.
, vol.7
, pp. 1199-1209
-
-
Leicht, M.1
Simm, A.2
Bertsch, G.3
Hoppe, J.4
-
97
-
-
0000906170
-
Induction of autophagy and inhibition of tumorigenesis by beclin 1
-
Liang, X. H., S. Jackson, M. Seaman, K. Brown, B. Kempkes, H. Hibshoosh, and B. Levine. 1999. Induction of autophagy and inhibition of tumorigenesis by beclin 1. Nature 402:672-676.
-
(1999)
Nature
, vol.402
, pp. 672-676
-
-
Liang, X.H.1
Jackson, S.2
Seaman, M.3
Brown, K.4
Kempkes, B.5
Hibshoosh, H.6
Levine, B.7
-
98
-
-
0027524176
-
RTG1 and RTG2: Two yeast genes required for a novel path of communication from mitochondria to the nucleus
-
Liao, X., and R. A. Butow. 1993. RTG1 and RTG2: Two yeast genes required for a novel path of communication from mitochondria to the nucleus. Cell 72:61-71.
-
(1993)
Cell
, vol.72
, pp. 61-71
-
-
Liao, X.1
Butow, R.A.2
-
99
-
-
0026085418
-
Intramitochondrial functions regulate nonmitochondrial citrate synthase (CIT2) expression in Saccharomyces cerevisiae
-
Liao, X. S., W. C. Small, P. A. Srere, and R. A. Butow. 1991. Intramitochondrial functions regulate nonmitochondrial citrate synthase (CIT2) expression in Saccharomyces cerevisiae. Mol. Cell. Biol. 11:38-46.
-
(1991)
Mol. Cell. Biol.
, vol.11
, pp. 38-46
-
-
Liao, X.S.1
Small, W.C.2
Srere, P.A.3
Butow, R.A.4
-
100
-
-
0028126506
-
PHAS-I as a link between mitogen-activated protein kinase and translation initiation
-
Lin, T. A., X. Kong, T. A. Haystead, A. Pause, G. Belsham, N. Sonenberg, and J. C. Lawrence, Jr. 1994. PHAS-I as a link between mitogen-activated protein kinase and translation initiation. Science 266:653-656.
-
(1994)
Science
, vol.266
, pp. 653-656
-
-
Lin, T.A.1
Kong, X.2
Haystead, T.A.3
Pause, A.4
Belsham, G.5
Sonenberg, N.6
Lawrence J.C., Jr.7
-
101
-
-
0028825698
-
TOR mutations confer rapamycin resistance by preventing interaction with FKBP12-rapamycin
-
Lorenz, M. C., and J. Heitman. 1995. TOR mutations confer rapamycin resistance by preventing interaction with FKBP12-rapamycin. J. Biol. Chem. 270: 27531-27537.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 27531-27537
-
-
Lorenz, M.C.1
Heitman, J.2
-
102
-
-
0000025835
-
Regulation of nitrogen utilization
-
E. W. Jones, J. R. Pringle, and J. R. Broach (ed.), Cold Spring Harbor Laboratory. Press. Cold Spring Harbor, N.Y
-
Magasanik, B. 1992. Regulation of nitrogen utilization, p. 283-317. In E. W. Jones, J. R. Pringle, and J. R. Broach (ed.), The Molecular and Cellular Biology of the Yeast Saccharomyces: Gene Expression, vol. 2. Cold Spring Harbor Laboratory. Press. Cold Spring Harbor, N.Y.
-
(1992)
The Molecular and Cellular Biology of the Yeast Saccharomyces: Gene Expression
, vol.2
, pp. 283-317
-
-
Magasanik, B.1
-
103
-
-
0027931137
-
Modulation of transcription of rRNA genes by rapamycin
-
Mahajan, P. B. 1994. Modulation of transcription of rRNA genes by rapamycin. Int. J. Immunopharmacol. 16:711-721.
-
(1994)
Int. J. Immunopharmacol.
, vol.16
, pp. 711-721
-
-
Mahajan, P.B.1
-
104
-
-
0029656153
-
Constitutive activation of S6 kinase by deletion of amino-terminal autoinhibitory and rapamycin sensitivity domains
-
Mahalingam, M., and D. J. Templeton. 1996. Constitutive activation of S6 kinase by deletion of amino-terminal autoinhibitory and rapamycin sensitivity domains. Mol. Cell. Biol. 16:405-413.
-
(1996)
Mol. Cell. Biol.
, vol.16
, pp. 405-413
-
-
Mahalingam, M.1
Templeton, D.J.2
-
105
-
-
0030983504
-
Apg1p, a novel protein kinase required for the autophagic process in Saccharomyces cerevisiae
-
Matsuura, A., M. Tsukada, Y. Wada, and Y. Ohsumi. 1997. Apg1p, a novel protein kinase required for the autophagic process in Saccharomyces cerevisiae. Gene 192:245-250.
-
(1997)
Gene
, vol.192
, pp. 245-250
-
-
Matsuura, A.1
Tsukada, M.2
Wada, Y.3
Ohsumi, Y.4
-
106
-
-
0037197930
-
Expression and disruption of the Arabidopsis TOR (target of rapamycin) gene
-
Menand, B., T. Desnos, L. Nussaume, F. Berger, D. Bouchez, C. Meyer, and C. Robaglia. 2002. Expression and disruption of the Arabidopsis TOR (target of rapamycin) gene. Proc. Natl. Acad. Sci. USA 99:6422-6427.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 6422-6427
-
-
Menand, B.1
Desnos, T.2
Nussaume, L.3
Berger, F.4
Bouchez, D.5
Meyer, C.6
Robaglia, C.7
-
107
-
-
0002921709
-
Translational control of TOP mRNAs
-
N. Sonenberg, J. W. B. Hershey, and M. B. Mathews (ed.), Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y
-
Meyuhas, O., and E. Hornstein. 2000. Translational control of TOP mRNAs, p. 671-693. In N. Sonenberg, J. W. B. Hershey, and M. B. Mathews (ed.), Translational control of gene expression. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
-
(2000)
Translational Control of Gene Expression
, pp. 671-693
-
-
Meyuhas, O.1
Hornstein, E.2
-
108
-
-
0034976004
-
The translational inhibitor 4E-BP is an effector of PI(3)K/Akt signalling and cell growth in Drosophila
-
Miron, M., J. Verdu, P. E. Lachance, M. J. Birnbaum, P. F. Lasko, and N. Sonenberg. 2001. The translational inhibitor 4E-BP is an effector of PI(3)K/ Akt signalling and cell growth in Drosophila. Nat. Cell Biol. 3:596-601.
-
(2001)
Nat. Cell Biol.
, vol.3
, pp. 596-601
-
-
Miron, M.1
Verdu, J.2
Lachance, P.E.3
Birnbaum, M.J.4
Lasko, P.F.5
Sonenberg, N.6
-
109
-
-
0030984108
-
B cell receptor-associated protein alpha4 displays rapamycin-sensitive binding directly to the catalytic subunit of protein phosphatase 2A
-
Murata, K., J. Wu, and D. L. Brautigan. 1997. B cell receptor-associated protein alpha4 displays rapamycin-sensitive binding directly to the catalytic subunit of protein phosphatase 2A. Proc. Natl. Acad. Sci. USA 94: 10624-10629.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 10624-10629
-
-
Murata, K.1
Wu, J.2
Brautigan, D.L.3
-
110
-
-
0033033091
-
Alpha4 protein as a common regulator of type 2A-related serine/threonine protein phosphatases
-
Nanahoshi, M., Y. Tsujishita, C. Tokunaga, S. Inui, N. Sakaguchi, K. Hara, and K. Yonezawa. 1999. Alpha4 protein as a common regulator of type 2A-related serine/threonine protein phosphatases. FEBS Lett. 446:108-112.
-
(1999)
FEBS Lett.
, vol.446
, pp. 108-112
-
-
Nanahoshi, M.1
Tsujishita, Y.2
Tokunaga, C.3
Inui, S.4
Sakaguchi, N.5
Hara, K.6
Yonezawa, K.7
-
111
-
-
0027582189
-
Control of the yeast cell cycle by the Cdc28 protein kinase
-
Nasmyth, K. 1993. Control of the yeast cell cycle by the Cdc28 protein kinase. Curr. Opin. Cell Biol. 5:166-179.
-
(1993)
Curr. Opin. Cell Biol.
, vol.5
, pp. 166-179
-
-
Nasmyth, K.1
-
112
-
-
0033429554
-
Mammalian target of rapamycin is a direct target for protein kinase B: Identification of a convergence point for opposing effects of insulin and amino-acid deficiency on protein translation
-
Nave, B. T., M. Ouwens, D. J. Withers, D. R. Alessi, and P. R. Shepherd. 1999. Mammalian target of rapamycin is a direct target for protein kinase B: Identification of a convergence point for opposing effects of insulin and amino-acid deficiency on protein translation. Biochem. J. 344:427-431.
-
(1999)
Biochem. J.
, vol.344
, pp. 427-431
-
-
Nave, B.T.1
Ouwens, M.2
Withers, D.J.3
Alessi, D.R.4
Shepherd, P.R.5
-
113
-
-
0032512636
-
Tor, a phosphatidylinositol kinase homologue, controls autophagy in yeast
-
Noda, T., and Y. Ohsumi. 1998. Tor, a phosphatidylinositol kinase homologue, controls autophagy in yeast. J. Biol. Chem. 273:3963-3966.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 3963-3966
-
-
Noda, T.1
Ohsumi, Y.2
-
114
-
-
0034312279
-
Genetic and biochemical characterization of dTOR, the Drosophila homolog of the target of rapamycin
-
Oldham, S., J. Montagne, T. Radimerski, G. Thomas, and E. Hafen. 2000. Genetic and biochemical characterization of dTOR, the Drosophila homolog of the target of rapamycin. Genes Dev. 14:2689-2694.
-
(2000)
Genes Dev.
, vol.14
, pp. 2689-2694
-
-
Oldham, S.1
Montagne, J.2
Radimerski, T.3
Thomas, G.4
Hafen, E.5
-
115
-
-
0028034233
-
Insulin-dependent stimulation of protein synthesis by phosphorylation of a regulator of 5′-cap function
-
Pause, A., G. J. Belsham, A. C. Gingras, O. Donze, T. A. Lin, J. C. Lawrence, Jr., and N. Sonenberg. 1994. Insulin-dependent stimulation of protein synthesis by phosphorylation of a regulator of 5′-cap function. Nature 371:762-767.
-
(1994)
Nature
, vol.371
, pp. 762-767
-
-
Pause, A.1
Belsham, G.J.2
Gingras, A.C.3
Donze, O.4
Lin, T.A.5
Lawrence J.C., Jr.6
Sonenberg, N.7
-
116
-
-
0036310982
-
The immunosuppressant rapamycin mimics a starvation-like signal distinct from amino Acid and glucose deprivation
-
Peng, T., T. R. Golub, and D. M. Sabatini. 2002. The immunosuppressant rapamycin mimics a starvation-like signal distinct from amino Acid and glucose deprivation. Mol. Cell. Biol. 22:5575-5584.
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 5575-5584
-
-
Peng, T.1
Golub, T.R.2
Sabatini, D.M.3
-
117
-
-
0034629365
-
FKBP12-rapamycin-associated protein (FRAP) autophosphory]ates at serine 2481 under translationally repressive conditions
-
Peterson, R. T., P. A. Beal, M. J. Comb, and S. L. Schreiber. 2000. FKBP12-rapamycin-associated protein (FRAP) autophosphory]ates at serine 2481 under translationally repressive conditions. J. Biol. Chem. 275:7416-7423.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 7416-7423
-
-
Peterson, R.T.1
Beal, P.A.2
Comb, M.J.3
Schreiber, S.L.4
-
118
-
-
0033551234
-
Protein phosphatase 2A interacts with the 70-kDa S6 kinase and is activated by inhibition of FKBP12-rapamycinassociated protein
-
Peterson, R. T., B. N. Desai, J. S. Hardwick, and S. L. Schreiber. 1999. Protein phosphatase 2A interacts with the 70-kDa S6 kinase and is activated by inhibition of FKBP12-rapamycinassociated protein. Proc. Natl. Acad. Sci. USA 96:4438-4442.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 4438-4442
-
-
Peterson, R.T.1
Desai, B.N.2
Hardwick, J.S.3
Schreiber, S.L.4
-
120
-
-
0032577691
-
4E-BP3, a new member of the eukaryotic initiation factor 4E-binding protein family
-
Poulin, F., A. C. Gingras, H. Olsen, S. Chevalier, and N. Sonenberg. 1998. 4E-BP3, a new member of the eukaryotic initiation factor 4E-binding protein family. J. Biol. Chem. 273:14002-14007.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 14002-14007
-
-
Poulin, F.1
Gingras, A.C.2
Olsen, H.3
Chevalier, S.4
Sonenberg, N.5
-
121
-
-
0032915417
-
Regulation of ribosome biogenesis by the rapamycin-sensitive TOR-signaling pathway in Saccharomyces cerevisiae
-
Powers, T., and P. Walter. 1999. Regulation of ribosome biogenesis by the rapamycin-sensitive TOR-signaling pathway in Saccharomyces cerevisiae. Mol. Biol. Cell 10:987-1000.
-
(1999)
Mol. Biol. Cell
, vol.10
, pp. 987-1000
-
-
Powers, T.1
Walter, P.2
-
122
-
-
0026759874
-
Rapamycin-induced inhibition of the 70-kilodalton S6 protein kinase
-
Price, D. J., J. R. Grove, V. Calvo, J. Avruch, and B. E. Bierer. 1992. Rapamycin-induced inhibition of the 70-kilodalton S6 protein kinase. Science 257:973-977.
-
(1992)
Science
, vol.257
, pp. 973-977
-
-
Price, D.J.1
Grove, J.R.2
Calvo, V.3
Avruch, J.4
Bierer, B.E.5
-
123
-
-
0034141942
-
Serum-stimulated, rapamycin-sensitive phosphorylation sites in the eukaryotic translation initiation factor 4GI
-
Raught, B., A. C. Gingras, S. P. Gygi, H. Imataka, S. Morino, A. Gradi, R. Aebersold, and N. Sonenberg. 2000. Serum-stimulated, rapamycin-sensitive phosphorylation sites in the eukaryotic translation initiation factor 4GI. EMBO J. 19:434-444.
-
(2000)
EMBO J.
, vol.19
, pp. 434-444
-
-
Raught, B.1
Gingras, A.C.2
Gygi, S.P.3
Imataka, H.4
Morino, S.5
Gradi, A.6
Aebersold, R.7
Sonenberg, N.8
-
124
-
-
0001902617
-
Regulation of ribosomal recruitment in eukaryotes
-
N. Sonenberg, J. W. B. Hershey, and M. B. Mathews (ed.), Cold Spring Harbor Laboratory. Press, Cold Spring Harbor, N.Y
-
Raught, B., A. C. Gingras, and N. Sonenberg. 2000. Regulation of ribosomal recruitment in eukaryotes, p. 245-293. In N. Sonenberg, J. W. B. Hershey, and M. B. Mathews (ed.), Translational control of gene expression. Cold Spring Harbor Laboratory. Press, Cold Spring Harbor, N.Y.
-
(2000)
Translational Control of Gene Expression
, pp. 245-293
-
-
Raught, B.1
Gingras, A.C.2
Sonenberg, N.3
-
125
-
-
0035971180
-
The TOR kinases link nutrient sensing to cell growth
-
Rohde, J., J. Heitman, and M. E. Cardenas. 2001. The TOR kinases link nutrient sensing to cell growth. J. Biol. Chem. 276:9583-9586.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 9583-9586
-
-
Rohde, J.1
Heitman, J.2
Cardenas, M.E.3
-
126
-
-
0033553624
-
Interaction of RAFT1 with gephyrin required for rapamycin-sensitive signaling
-
Sabatini, D. M., R. K. Barrow, S. Blackshaw, P. E. Burnett, M. M. Lai, M. E. Field, B. A. Bahr, J. Kirsch, H. Betz, and S. H. Snyder. 1999. Interaction of RAFT1 with gephyrin required for rapamycin-sensitive signaling. Science 284:1161-1164.
-
(1999)
Science
, vol.284
, pp. 1161-1164
-
-
Sabatini, D.M.1
Barrow, R.K.2
Blackshaw, S.3
Burnett, P.E.4
Lai, M.M.5
Field, M.E.6
Bahr, B.A.7
Kirsch, J.8
Betz, H.9
Snyder, S.H.10
-
127
-
-
0028239893
-
RAFT1: A mammalian protein that binds to FKBP12 in a rapamycin-dependent fashion and is homologous to yeast TORs
-
Sabatini, D. M., H. Erdjument-Bromage, M. Lui, P. Tempst, and S. H. Snyder. 1994. RAFT1: A mammalian protein that binds to FKBP12 in a rapamycin-dependent fashion and is homologous to yeast TORs. Cell 78: 35-43.
-
(1994)
Cell
, vol.78
, pp. 35-43
-
-
Sabatini, D.M.1
Erdjument-Bromage, H.2
Lui, M.3
Tempst, P.4
Snyder, S.H.5
-
128
-
-
0028950217
-
Isolation of a protein target of the FKBP12-rapamycin complex in mammalian cells
-
Sabers, C. J., M. M. Martin, G. J. Brunn, J. M. Williams, F. J. Dumont, G. Wiederrecht, and R. T. Abraham. 1995. Isolation of a protein target of the FKBP12-rapamycin complex in mammalian cells. J. Biol. Chem. 270:815-822.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 815-822
-
-
Sabers, C.J.1
Martin, M.M.2
Brunn, G.J.3
Williams, J.M.4
Dumont, F.J.5
Wiederrecht, G.6
Abraham, R.T.7
-
129
-
-
0001417555
-
GATE-16, a membrane transport modulator, interacts with NSF and the Golgi v-SNARE GOS-28
-
Sagiv, Y., A. Legesse-Miller, A. Porat, and Z. Elazar. 2000. GATE-16, a membrane transport modulator, interacts with NSF and the Golgi v-SNARE GOS-28. EMBO J. 19:1494-1504.
-
(2000)
EMBO J.
, vol.19
, pp. 1494-1504
-
-
Sagiv, Y.1
Legesse-Miller, A.2
Porat, A.3
Elazar, Z.4
-
130
-
-
0034644525
-
TOR, a central controller of cell growth
-
Schmelzle, T., and M. N. Hall. 2000. TOR, a central controller of cell growth. Cell 103:253-262.
-
(2000)
Cell
, vol.103
, pp. 253-262
-
-
Schmelzle, T.1
Hall, M.N.2
-
131
-
-
0032403058
-
The TOR nutrient signalling pathway phosphorylates NPR1 and inhibits turnover of the tryptophan permease
-
Schmidt, A., T. Beck, A. Koller, J. Kunz, and M. N. Hall. 1998. The TOR nutrient signalling pathway phosphorylates NPR1 and inhibits turnover of the tryptophan permease. EMBO J. 17:6924-6931.
-
(1998)
EMBO J.
, vol.17
, pp. 6924-6931
-
-
Schmidt, A.1
Beck, T.2
Koller, A.3
Kunz, J.4
Hall, M.N.5
-
132
-
-
0030906569
-
The yeast phosphatidylinositol kinase homolog TOR2 activates RHO1 and RHO2 via the exchange factor ROM2
-
Schmidt, A., M. Bickle, T. Beck, and M. N. Hall. 1997. The yeast phosphatidylinositol kinase homolog TOR2 activates RHO1 and RHO2 via the exchange factor ROM2. Cell 88:531-542.
-
(1997)
Cell
, vol.88
, pp. 531-542
-
-
Schmidt, A.1
Bickle, M.2
Beck, T.3
Hall, M.N.4
-
134
-
-
0030479340
-
TOR2 is required for organization of the actin cytoskeieton in yeast
-
Schmidt, A., J. Kunz, and M. N. Hall. 1996. TOR2 is required for organization of the actin cytoskeieton in yeast. Proc. Natl. Acad. Sci. USA 93: 13780-13785.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 13780-13785
-
-
Schmidt, A.1
Kunz, J.2
Hall, M.N.3
-
135
-
-
0026030568
-
Chemistry and biology of the immunophilins and their immunosuppressive ligands
-
Schreiber, S. L. 1991. Chemistry and biology of the immunophilins and their immunosuppressive ligands. Science 251:283-287.
-
(1991)
Science
, vol.251
, pp. 283-287
-
-
Schreiber, S.L.1
-
136
-
-
0026625939
-
Immunophilin-sensitive protein phosphatase action in cell signaling pathways
-
Schreiber, S. L. 1992. Immunophilin-sensitive protein phosphatase action in cell signaling pathways. Cell 70:365-368.
-
(1992)
Cell
, vol.70
, pp. 365-368
-
-
Schreiber, S.L.1
-
137
-
-
0032560521
-
Evidence of insulin-stimulated phosphorylation and activation of the mammalian target of rapamycin mediated by a protein kinase B signaling pathway
-
Scott, P. H., G. J. Brunn, A. D. Kohn, R. A. Roth, and J. C. Lawrence, Jr. 1998. Evidence of insulin-stimulated phosphorylation and activation of the mammalian target of rapamycin mediated by a protein kinase B signaling pathway. Proc. Natl. Acad. Sci. USA 95:7772-7777.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 7772-7777
-
-
Scott, P.H.1
Brunn, G.J.2
Kohn, A.D.3
Roth, R.A.4
Lawrence J.C., Jr.5
-
138
-
-
0036200999
-
RTG-dependent mitochondria-to-nucleus signaling is regulated by MKS1 and is linked to formation of yeast prion [URE3]
-
Sekito, T., Z. Liu, J. Thornton, and R. A. Butow. 2002. RTG-dependent mitochondria-to-nucleus signaling is regulated by MKS1 and is linked to formation of yeast prion [URE3]. Mol. Biol. Cell 13:795-804.
-
(2002)
Mol. Biol. Cell
, vol.13
, pp. 795-804
-
-
Sekito, T.1
Liu, Z.2
Thornton, J.3
Butow, R.A.4
-
139
-
-
0034234924
-
A direct linkage between the phosphoinositide 3-kinase-AKT signaling pathway and the mammalian target of rapamycin in mitogen-stimulated and transformed cells
-
Sekulic, A., C. C. Hudson, J. L. Homme, P. Yin, D. M. Otterness, L. M. Karnitz, and R. T. Abraham. 2000. A direct linkage between the phosphoinositide 3-kinase-AKT signaling pathway and the mammalian target of rapamycin in mitogen-stimulated and transformed cells. Cancer Res. 60: 3504-3513.
-
(2000)
Cancer Res.
, vol.60
, pp. 3504-3513
-
-
Sekulic, A.1
Hudson, C.C.2
Homme, J.L.3
Yin, P.4
Otterness, D.M.5
Karnitz, L.M.6
Abraham, R.T.7
-
140
-
-
0034649569
-
Partitioning the transcriptional program induced by rapamycin among the effectors of the Tor proteins
-
Shamji, A. F., F. G. Kuruvilla, and S. L. Schreiber. 2000. Partitioning the transcriptional program induced by rapamycin among the effectors of the Tor proteins. Curr. Biol. 10:1574-1581.
-
(2000)
Curr. Biol.
, vol.10
, pp. 1574-1581
-
-
Shamji, A.F.1
Kuruvilla, F.G.2
Schreiber, S.L.3
-
141
-
-
0033534734
-
Regulation of translational effectors by amino acid and mammalian target of rapamycin signaling pathways. Possible involvement of autophagy in cultured hepatoma cells
-
Shigemitsu, K., Y. Tsujishita, K. Hara, M. Nanahoshi, J. Avruch, and K. Yonezawa. 1999. Regulation of translational effectors by amino acid and mammalian target of rapamycin signaling pathways. Possible involvement of autophagy in cultured hepatoma cells. J. Biol. Chem. 274:1058-1065.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 1058-1065
-
-
Shigemitsu, K.1
Tsujishita, Y.2
Hara, K.3
Nanahoshi, M.4
Avruch, J.5
Yonezawa, K.6
-
142
-
-
0026748870
-
Cyclosporin A, FK-506, and rapamycin: Pharmacologic probes of lymphocyte signal transduction
-
Sigal, N. H., and F. J. Dumont. 1992. Cyclosporin A, FK-506, and rapamycin: Pharmacologic probes of lymphocyte signal transduction. Annu. Rev. Immunol. 10:519-560.
-
(1992)
Annu. Rev. Immunol.
, vol.10
, pp. 519-560
-
-
Sigal, N.H.1
Dumont, F.J.2
-
143
-
-
0032127462
-
Yeast PKA represses Msn2p/Msn4p-dependent gene expression to regulate growth, stress response and glycogen accumulation
-
Smith, A., M. P. Ward, and S. Garrett. 1998. Yeast PKA represses Msn2p/Msn4p-dependent gene expression to regulate growth, stress response and glycogen accumulation. EMBO J. 17:3556-3564.
-
(1998)
EMBO J.
, vol.17
, pp. 3556-3564
-
-
Smith, A.1
Ward, M.P.2
Garrett, S.3
-
144
-
-
0028798082
-
Amino acid transporters of lower eukaryotes: Regulation, structure and topogenesis
-
Sophianopoulou, V., and G. Diallinas. 1995. Amino acid transporters of lower eukaryotes: Regulation, structure and topogenesis. FEMS Microbiol. Rev. 16:53-75.
-
(1995)
FEMS Microbiol. Rev.
, vol.16
, pp. 53-75
-
-
Sophianopoulou, V.1
Diallinas, G.2
-
145
-
-
0028561918
-
Interaction between FKBP12-rapamycin and TOR involves a conserved serine residue
-
Stan, R., M. M. McLaughlin, R. Cafferkey, R. K. Johnson, M. Rosenberg, and G. P. Livi. 1994. Interaction between FKBP12-rapamycin and TOR involves a conserved serine residue. J. Biol. Chem. 269:32027-32030.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 32027-32030
-
-
Stan, R.1
McLaughlin, M.M.2
Cafferkey, R.3
Johnson, R.K.4
Rosenberg, M.5
Livi, G.P.6
-
146
-
-
0028832649
-
Role of the GATA factors Gln3p and Ni11p of Saccharomyces cerevisiae in the expression of nitrogen-regulated genes
-
Stanbrough, M., D. W. Rowen, and B. Magasanik. 1995. Role of the GATA factors Gln3p and Ni11p of Saccharomyces cerevisiae in the expression of nitrogen-regulated genes. Proc. Natl. Acad. Sci. USA 92:9450-9454.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 9450-9454
-
-
Stanbrough, M.1
Rowen, D.W.2
Magasanik, B.3
-
147
-
-
0034910768
-
Approaching the molecular mechanism of autophagy
-
Stromhaug, P. E., and D. J. Klionsky. 2001. Approaching the molecular mechanism of autophagy. Traffic 2:524-531.
-
(2001)
Traffic
, vol.2
, pp. 524-531
-
-
Stromhaug, P.E.1
Klionsky, D.J.2
-
148
-
-
0032730328
-
Opposite translational control of GLUT1 and GLUT4 glucose transporter mRNAs in response to insulin. Role of mammalian target of rapamycin, protein kinase b, and phosphatidylinositol 3-kinase in GLUT1 mRNA MRNA translation
-
Taha, C., Z. Liu, J. Jin, H. Al-Hasani, N. Sonenberg, and A. Klip. 1999. Opposite translational control of GLUT1 and GLUT4 glucose transporter mRNAs in response to insulin. Role of mammalian target of rapamycin, protein kinase b, and phosphatidylinositol 3-kinase in GLUT1 mRNA MRNA translation. J. Biol. Chem. 274:33085-33091.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 33085-33091
-
-
Taha, C.1
Liu, Z.2
Jin, J.3
Al-Hasani, H.4
Sonenberg, N.5
Klip, A.6
-
149
-
-
0026668042
-
Autophagy in yeast demonstrated with proteinase-deficient mutants and conditions for its induction
-
Takeshige, K., M. Baba, S. Tsuboi, T. Noda, and Y. Ohsumi. 1992. Autophagy in yeast demonstrated with proteinase-deficient mutants and conditions for its induction. J. Cell Biol. 119:301-311.
-
(1992)
J. Cell Biol.
, vol.119
, pp. 301-311
-
-
Takeshige, K.1
Baba, M.2
Tsuboi, S.3
Noda, T.4
Ohsumi, Y.5
-
150
-
-
0035910423
-
The human homolog of Saccharomyces cerevisiae Apg7p is a Protein-activating enzyme for multiple substrates including human Apg12p, GATE-16, GABARAP, and MAP-LC3
-
Tanida, I., E. Tanida-Miyake, T. Ueno, and E. Kominami. 2001. The human homolog of Saccharomyces cerevisiae Apg7p is a Protein-activating enzyme for multiple substrates including human Apg12p, GATE-16, GABARAP, and MAP-LC3. J. Biol. Chem. 276:1701-1706.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 1701-1706
-
-
Tanida, I.1
Tanida-Miyake, E.2
Ueno, T.3
Kominami, E.4
-
151
-
-
0032835137
-
Novel sensing mechanisms and targets for the cAMP-protein kinase A pathway in the yeast Saccharomyces cerevisiae
-
Thevelein, J. M., and J. H. de Winde. 1999. Novel sensing mechanisms and targets for the cAMP-protein kinase A pathway in the yeast Saccharomyces cerevisiae. Mol. Microbiol. 33:904-918.
-
(1999)
Mol. Microbiol.
, vol.33
, pp. 904-918
-
-
Thevelein, J.M.1
De Winde, J.H.2
-
152
-
-
0030707562
-
TOR signalling and control of cell growth
-
Thomas, G., and M. N. Hall. 1997. TOR signalling and control of cell growth. Curr. Opin. Cell Biol. 9:782-787.
-
(1997)
Curr. Opin. Cell Biol.
, vol.9
, pp. 782-787
-
-
Thomas, G.1
Hall, M.N.2
-
153
-
-
0027424777
-
Isolation and characterization of autophagy-defective mutants of Saccharomyces cerevisiae
-
Tsukada, M., and Y. Ohsumi. 1993. Isolation and characterization of autophagy-defective mutants of Saccharomyces cerevisiae. FEBS Lett. 333: 169-174.
-
(1993)
FEBS Lett.
, vol.333
, pp. 169-174
-
-
Tsukada, M.1
Ohsumi, Y.2
-
154
-
-
0027173154
-
1 cyclins: Cln3 may be an upstream activator of Cln1, Cln2 and other cyclins
-
1 cyclins: Cln3 may be an upstream activator of Cln1, Cln2 and other cyclins. EMBO J. 12:1955-1968.
-
(1993)
EMBO J.
, vol.12
, pp. 1955-1968
-
-
Tyers, M.1
Tokiwa, G.2
Futcher, B.3
-
155
-
-
0023217215
-
Isolation of the NPR1 gene responsible for the reactivation of ammonia-sensitive amino-acid permeases in Saccharomyces cerevisiae. RNA analysis and gene dosage effects
-
Vandenbol, M., J. C. Jauniaux, S. Vissers, and M. Grenson. 1987. Isolation of the NPR1 gene responsible for the reactivation of ammonia-sensitive amino-acid permeases in Saccharomyces cerevisiae. RNA analysis and gene dosage effects. Eur. J. Biochem. 164:607-612.
-
(1987)
Eur. J. Biochem.
, vol.164
, pp. 607-612
-
-
Vandenbol, M.1
Jauniaux, J.C.2
Vissers, S.3
Grenson, M.4
-
156
-
-
0016724057
-
Rapamycin (AY-22,989), a new antifungal antibiotic. I. Taxonomy of the producing streptomycete and isolation of the active principle
-
Vezina, C., A. Kudelski, and S. N. Sehgal. 1975. Rapamycin (AY-22,989), a new antifungal antibiotic. I. Taxonomy of the producing streptomycete and isolation of the active principle. J. Antibiol. (Tokyo) 28:721-726.
-
(1975)
J. Antibiol. (Tokyo)
, vol.28
, pp. 721-726
-
-
Vezina, C.1
Kudelski, A.2
Sehgal, S.N.3
-
157
-
-
0029984354
-
4E-BP1 phosphorylation is mediated by the FRAP-p70s6k pathway and is independent of mitogen-activated protein kinase
-
von Manteuffel, S. R., A. C. Gingras, X. F. Ming, N. Sonenberg, and G. Thomas. 1996. 4E-BP1 phosphorylation is mediated by the FRAP-p70s6k pathway and is independent of mitogen-activated protein kinase. Proc. Natl. Acad. Sci. USA 93: 4076-4080.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 4076-4080
-
-
Von Manteuffel, S.R.1
Gingras, A.C.2
Ming, X.F.3
Sonenberg, N.4
Thomas, G.5
-
158
-
-
0032528917
-
Amino acid availability regulates p70 S6 kinase and multiple translation factors
-
Wang, X., L. E. Campbell, C. M. Miller, and C. G. Proud. 1998. Amino acid availability regulates p70 S6 kinase and multiple translation factors. Biochem. J. 334:261-267.
-
(1998)
Biochem. J.
, vol.334
, pp. 261-267
-
-
Wang, X.1
Campbell, L.E.2
Miller, C.M.3
Proud, C.G.4
-
159
-
-
0035881470
-
Regulation of elongation factor 2 kinase by p90(RSK1) and p70 S6 kinase
-
Wang, X., W. Li, M. Williams, N. Terada, D. R. Alessi, and C. G. Proud. 2001. Regulation of elongation factor 2 kinase by p90(RSK1) and p70 S6 kinase. EMBO J. 20:437-4379.
-
(2001)
EMBO J.
, vol.20
, pp. 437-4379
-
-
Wang, X.1
Li, W.2
Williams, M.3
Terada, N.4
Alessi, D.R.5
Proud, C.G.6
-
160
-
-
0033229970
-
The economics of ribosome biosynthesis in yeast
-
Warner, J. R. 1999. The economics of ribosome biosynthesis in yeast. Trends Biochem. Sci. 24:437-440.
-
(1999)
Trends Biochem. Sci.
, vol.24
, pp. 437-440
-
-
Warner, J.R.1
-
161
-
-
0035831446
-
The fission yeast TOR homolog, tor1+, is required for the response to starvation and other stresses via a conserved serine
-
Weisman, R., and M. Choder. 2001. The fission yeast TOR homolog, tor1+, is required for the response to starvation and other stresses via a conserved serine. J. Biol. Chem. 276:7027-7032.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 7027-7032
-
-
Weisman, R.1
Choder, M.2
-
162
-
-
0035816598
-
Rapamycin blocks sexual development in fission yeast through inhibition of the cellular function of an FKBP12 homolog
-
Weisman, R., S. Finkelstein, and M. Choder. 2001. Rapamycin blocks sexual development in fission yeast through inhibition of the cellular function of an FKBP12 homolog. J. Biol. Chem. 276:24736-24742.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 24736-24742
-
-
Weisman, R.1
Finkelstein, S.2
Choder, M.3
-
163
-
-
0029117304
-
Maximal activation of transcription by Stat1 and Stat3 requires both tyrosine and serine phosphorylation
-
Wen, Z., Z. Zhong, and J. E. Darnell, Jr. 1995. Maximal activation of transcription by Stat1 and Stat3 requires both tyrosine and serine phosphorylation. Cell 82:241-250.
-
(1995)
Cell
, vol.82
, pp. 241-250
-
-
Wen, Z.1
Zhong, Z.2
Darnell J.E., Jr.3
-
164
-
-
0026012054
-
FKB1 encodes a nonessential FK 506-binding protein in Saccharomyces cerevisiae and contains regions suggesting homology to the cyclophilins
-
Wiederrecht, G., L. Brizuela, K. Elliston, N. H. Sigal, and J. J. Siekierka. 1991. FKB1 encodes a nonessential FK 506-binding protein in Saccharomyces cerevisiae and contains regions suggesting homology to the cyclophilins. Proc. Natl. Acad. Sci. USA 88:1029-1033.
-
(1991)
Proc. Natl. Acad. Sci. USA
, vol.88
, pp. 1029-1033
-
-
Wiederrecht, G.1
Brizuela, L.2
Elliston, K.3
Sigal, N.H.4
Siekierka, J.J.5
-
165
-
-
0032561348
-
Branched-chain amino acids are essential in the regulation of PHAS-1 and p70 S6 kinase by pancreatic beta-cells. A possible role in protein translation and mitogenic signaling
-
Xu, G., G. Kwon, C. A. Marshall, T. A. Lin, J. C. Lawrence, Jr., and M. L. McDaniel. 1998. Branched-chain amino acids are essential in the regulation of PHAS-1 and p70 S6 kinase by pancreatic beta-cells. A possible role in protein translation and mitogenic signaling. J. Biol. Chem. 273:28178-28184.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 28178-28184
-
-
Xu, G.1
Kwon, G.2
Marshall, C.A.3
Lin, T.A.4
Lawrence J.C., Jr.5
McDaniel, M.L.6
-
166
-
-
0028983369
-
p34Cdc28-mediated control of Cln3 cyclin degradation
-
Yaglom, J., M. H. Linskens, S. Sadis, D. M. Rubin, B. Futcher, and D. Finley. 1995. p34Cdc28-mediated control of Cln3 cyclin degradation. Mol. Cell. Biol. 15:731-741.
-
(1995)
Mol. Cell. Biol.
, vol.15
, pp. 731-741
-
-
Yaglom, J.1
Linskens, M.H.2
Sadis, S.3
Rubin, D.M.4
Futcher, B.5
Finley, D.6
-
167
-
-
0033968596
-
Serine phosphorylation and maximal activation of STAT3 during ciliary neurotrophic factor signaling is mediated by the rapamycin target mTOR
-
Yokogami, K., S. Wakisaka, J. Avruch, and S. A. Reeves. 2000. Serine phosphorylation and maximal activation of STAT3 during ciliary neurotrophic factor signaling is mediated by the rapamycin target mTOR. Curr. Biol. 10:47-50.
-
(2000)
Curr. Biol.
, vol.10
, pp. 47-50
-
-
Yokogami, K.1
Wakisaka, S.2
Avruch, J.3
Reeves, S.A.4
-
169
-
-
0034312315
-
Regulation of cellular growth by the Drosophila target of rapamycin dTOR
-
Zhang, H., J. P. Stallock, J. C. Ng, C. Reinhard, and T. P. Neufeld. 2000. Regulation of cellular growth by the Drosophila target of rapamycin dTOR. Genes Dev. 14:2712-2724.
-
(2000)
Genes Dev.
, vol.14
, pp. 2712-2724
-
-
Zhang, H.1
Stallock, J.P.2
Ng, J.C.3
Reinhard, C.4
Neufeld, T.P.5
-
170
-
-
2642616985
-
Temperature-induced expression of yeast FKS2 is under the dual control of protein kinase C and calcineurin
-
Zhao, C., U. S. Jung, P. Garrett-Engele, T. Roe, M. S. Cyert, and D. E. Levin. 1998. Temperature-induced expression of yeast FKS2 is under the dual control of protein kinase C and calcineurin. Mol. Cell. Biol. 18:1013-1022.
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 1013-1022
-
-
Zhao, C.1
Jung, U.S.2
Garrett-Engele, P.3
Roe, T.4
Cyert, M.S.5
Levin, D.E.6
-
171
-
-
0029071264
-
TOR kinase domains are required for two distinct functions, only one of which is inhibited by rapamycin
-
Zheng, X. F., D. Florentino, J. Chen, G. R. Crabtree, and S. L. Schreiber. 1995. TOR kinase domains are required for two distinct functions, only one of which is inhibited by rapamycin. Cell 82:121-130.
-
(1995)
Cell
, vol.82
, pp. 121-130
-
-
Zheng, X.F.1
Florentino, D.2
Chen, J.3
Crabtree, G.R.4
Schreiber, S.L.5
|