4E-BP1 phosphorylation is mediated by the FRAP-p70s6k pathway and is independent of mitogen-activated protein kinase

Proceedings of the National Academy of Sciences of the United States of America

Volumn 93, Issue 9, 1996, Pages 4076-4080

  Von Manteuffel, Sabine R ^a   Gingras, Anne Claude ^b   Ming, Xiu Feng ^a   Sonenberg, Nahum ^b   Thomas, George ^a  

^a FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH   (Switzerland)

^b MCGILL UNIVERSITY   (Canada)

Author keywords

Insulin; Signal transduction; Translational control

Indexed keywords

1 ETHYL 4 HYDRAZINO 1H PYRAZOLO[3,4 B]PYRIDINE 5 CARBOXYLIC ACID ETHYL ESTER; ANISOMYCIN; INITIATION FACTOR 4E; INSULIN; MITOGEN ACTIVATED PROTEIN KINASE; PHORBOL 13 ACETATE 12 MYRISTATE; PLATELET DERIVED GROWTH FACTOR RECEPTOR; PROTEIN KINASE; PROTEIN KINASE INHIBITOR; PROTEIN KINASE P 70; RAPAMYCIN; REPRESSOR PROTEIN; REPRESSOR PROTEIN 4E BP 1; UNCLASSIFIED DRUG; WORTMANNIN;

ANIMAL CELL; AORTA; ARTICLE; CELL STRAIN 3T3; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME ACTIVATION; HUMAN; HUMAN CELL; KIDNEY CELL; MOUSE; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; SWINE;

3T3 CELLS; ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANDROSTADIENES; ANIMALS; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; CARRIER PROTEINS; CELL LINE; ENZYME ACTIVATION; ENZYME INHIBITORS; HUMANS; IMMUNOSUPPRESSIVE AGENTS; INSULIN; KIDNEY; KINETICS; MICE; NICOTINIC ACIDS; PHOSPHODIESTERASE INHIBITORS; PHOSPHOPROTEINS; PHOSPHORYLATION; POLYENES; PROTEIN-SERINE-THREONINE KINASES; RIBOSOMAL PROTEIN S6 KINASES; SIGNAL TRANSDUCTION; SIROLIMUS; TETRADECANOYLPHORBOL ACETATE;

EID: 0029984354     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.93.9.4076     Document Type: Article

References (33)

1. Lin, T. A., Kong, X., Haystead, T. A. J., Pause, A., Belsham, G., Sonenberg, N. & Lawrence, J. C., Jr. (1994) Science 266, 653-656.
2. Pause, A., Belsham, G. J., Gingras, A.-C., Donzé, O., Lin, T. A., Lawrence, J. C., Jr., & Sonenberg, N. (1994) Nature (London) 371, 762-767.
3. Mader, S., Lee, H., Pause, A. & Sonenberg, N. (1995) Mol. Cell. Biol. 15, 4990-4997.
4. Haghighat, A., Mader, S., Pause, A. & Sonenberg, N. (1995) EMBO J. 14, 5701-5709.
5. Lazaris-Karatzas, A., Montine, K. S. & Sonenberg, N. (1990) Nature (London) 345, 544-547.
6. Beretta, L., Gingras, A.-C., Svitkin, Y. V., Hall, M. N. & Sonenberg, N. (1996) EMBO J. 15, 658-664.
7. Chung, J., Kuo, C. J., Crabtree, G. R. & Blenis, J. (1992) Cell 69, 1227-1236.
8. Chung, J., Grammer, T. C., Lemon, K. P., Kazlauskas, A. & Blenis, J. (1994) Nature (London) 370, 71-75.
9. Han, J. W., Pearson, R. B., Dennis, P. B. & Thomas, G. (1995) J. Biol. Chem. 270, 21396-21403.
10. Ming, X. F., Burgering, B. M. T., Wennström, S., Claesson-Welsh, L., Heldin, C. H., Bos, J. L., Kozma, S. C. & Thomas, G. (1994) Nature (London) 371, 426-429.
11. Brown, E. J., Albers, M. A., Shin, T. B., Ichikawa, K., Keith, C. T., Lane, W. S. & Schreiber, S. L. (1994) Nature (London) 369, 756-758.
12. Sabatini, D. M., Erdjument-Bronage, H., Lui, M., Tempst, P. & Synder, S. H. (1994) Cell 78, 35-43.
13. Sabers, C. J., Martin, M. M., Brunn, G. J., Williams, J. M., Dumont, F. J., Wiederrecht, G. & Abraham, R. T. (1995) J. Biol. Chem. 270, 815-822.
14. Brown, E. J., Beal, P. A., Keith, C. T., Chen, J., Shin, T. B. & Schreiber, S. L. (1995) Nature (London) 377, 441-446.
15. Ballou, L. M., Luther, H. & Thomas, G. (1991) Nature (London) 349, 348-350.
16. Thomas, G., Martin-Perez, J., Siegmann, M. & Otto, A.M. (1982) Cell 30, 235-242.
17. Westermark, B., Siegbahn, A., Heldin, C. H. & Claesson-Welsh, L. (1990) Proc. Natl. Acad. Sci. USA 87, 128-132.
18. Gingras, A. L. C., Svitkin, Y., Belsham, G. J., Pause, A. & Sonenberg, N. (1996) Proc. Natl. Acad. Sci. USA, in press.
19. Lane, H. A., Morley, S. J., Doree, M., Kozma, S. C. & Thomas, G. (1992) EMBO J. 11, 1743-1749.
20. Marais, R., Wynne, J. & Treisman, R. (1993) Cell 73, 381-393.
21. Lane, H. A., Fernandez, A., Lamb, N. J. C. & Thomas, G. (1993) Nature (London) 363, 170-172.
22. Mahadevan, L. C. & Edwards, D. R. (1991) Nature (London) 349, 747-748.
23. Kardalinou, E., Zhelev, N., Hazzalin, C. A. & Mahadevan, L. C. (1994) Mol. Cell. Biol. 14, 1066-1074.
24. Wennström, S., Siegbahn, A., Yokote, K., Arvidsson, A. C., Heldin, C. H., Mori, S. & Claesson-Welsh, L. (1994) Oncogene 9, 651-660.
25. Haystead, T. A. J., Haystead, C. M. M., Hu, C., Lin, T. A. & Lawrence, J. C., Jr. (1994) J. Biol. Chem. 269, 23185-23191.
26. Graves, L. M., Bornfeldt, K. E., Argast, G. M., Krebs, E. G., Kong, X., Lin, T. A. & Lawrence, J. C., Jr. (1995) Proc. Natl. Acad. Sci. USA 92, 7222-7226.
27. Lin, T. A., Kong, X., Saltiel, A. R., Blackshear, P. J. & Lawrence, J. C., Jr. (1995) J. Biol. Chem. 270, 18531-18538.
28. Flotow, H. & Thomas, G. (1992) J. Biol. Chem. 267, 3074-3078.
29. Pearson, R. B., Dennis, P. B., Han, J. W., Williamson, N. A., Kozma, S. C., Wettenhall, R. E. H. & Thomas, G. (1996) EMBO J. 14, 5279-5287.
30. Olivier, A. R., Ballou, L. M. & Thomas, G. (1988) Proc. Natl. Acad. Sci. USA 85, 4720-4724.
31. Jefferies, H. B. J., Reinhard, C., Kozma, S. C. & Thomas, G. (1994) Proc. Natl. Acad. Sci. USA 91, 4441-4445.
32. Shama, S., Avni, D., Frederickson, R. A., Sonenberg, N. & Meyuhas, O. (1995) Gene Expression 4, 241-252.
33. Barbet, N. C., Schneider, U., Helliwell, S. B., Stansfield, I., Tuite, M. F. & Hall, M. N. (1996) Mol. Biol. Cell 7, 25-42.