Direct inhibition of the signaling functions of the mammalian target of rapamycin by the phosphoinositide 3-kinase inhibitors, wortmannin and LY294002

EMBO Journal

Volumn 15, Issue 19, 1996, Pages 5256-5267

  Brunn, Gregory J ^a   Williams, Josie ^b   Sabers, Candace ^a   Wiederrecht, Gregory ^c   Lawrence Jr , John C ^d   Abraham, Robert T ^a,b  

^a MAYO CLINIC   (United States)

^b MAYO GRADUATE SCHOOL   (United States)

^c MERCK RESEARCH LABORATORIES   (United States)

^d WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Cell cycle; Phosphatidylinositol 3 kinase; Rapamycin; Translation; Wortmannin

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; IMMUNOSUPPRESSIVE AGENT; INITIATION FACTOR; PHOSPHATIDYLINOSITIDE; PROTEIN KINASE; RAPAMYCIN; TRANSFERASE INHIBITOR; WORTMANNIN;

ANIMAL CELL; ARTICLE; CELL CYCLE G1 PHASE; CELL GROWTH; GROWTH INHIBITION; MOLECULAR WEIGHT; MOUSE; NONHUMAN; PHOSPHORYLATION; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; T LYMPHOCYTE; TRANSLATION INITIATION; YEAST ARTIFICIAL CHROMOSOME;

ANIMALIA; EUKARYOTA; MAMMALIA;

EID: 0029831167     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1002/j.1460-2075.1996.tb00911.x     Document Type: Article

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