TOR deficiency in C. elegans causes developmental arrest and intestinal atrophy by inhibition of mRNA translation

Current Biology

Volumn 12, Issue 17, 2002, Pages 1448-1461

  Long, Xiaomeng ^a   Spycher, Carmen ^b   Han, Z Stanley ^a   Rose, Ann M ^c   Müller, Fritz ^b   Avruch, Joseph ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b UNIVERSITY OF FRIBOURG   (Switzerland)

^c UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CAENORHABDITIS; CAENORHABDITIS ELEGANS; INVERTEBRATA;

CAENORHABDITIS ELEGANS PROTEIN; INITIATION FACTOR 2; INITIATION FACTOR 4G; LET 363 PROTEIN, C ELEGANS; LET-363 PROTEIN, C ELEGANS; MESSENGER RNA; PHOSPHOTRANSFERASE; RAPAMYCIN; S6 KINASE;

ADAPTATION; ALLELE; ANIMAL; ARTICLE; ATROPHY; CAENORHABDITIS ELEGANS; COMPARATIVE STUDY; GENE EXPRESSION REGULATION; GENE TARGETING; GENETIC COMPLEMENTATION; GENETICS; GROWTH, DEVELOPMENT AND AGING; INTESTINE; ISOLATION AND PURIFICATION; LARVA; LETHAL GENE; PATHOLOGY; PHENOTYPE; PHYSIOLOGY; PROTEIN SYNTHESIS; RNA INTERFERENCE; SEQUENCE HOMOLOGY; SPECIES DIFFERENCE; STARVATION;

ADAPTATION, PHYSIOLOGICAL; ALLELES; ANIMALS; ATROPHY; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; EUKARYOTIC INITIATION FACTOR-2; EUKARYOTIC INITIATION FACTOR-4G; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENE TARGETING; GENES, LETHAL; GENETIC COMPLEMENTATION TEST; INTESTINES; LARVA; PHENOTYPE; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR); PROTEIN BIOSYNTHESIS; RIBOSOMAL PROTEIN S6 KINASES, 70-KDA; RNA INTERFERENCE; RNA, MESSENGER; SEQUENCE HOMOLOGY, AMINO ACID; SIROLIMUS; SPECIES SPECIFICITY; STARVATION;

EID: 0037015269     PISSN: 09609822     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-9822(02)01091-6     Document Type: Article

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