Control of Nutrient-Sensitive Transcription Programs by the Unconventional Prefoldin URI

Science

Volumn 302, Issue 5648, 2003, Pages 1208-1212

  Gstaiger, Matthias ^a,b   Luke, Brian ^b   Hess, Daniel ^a   Oakeley, Edward J ^a   Wirbelauer, Christiane ^a   Blondel, Marc ^b,d   Vigneron, Marc ^c   Peter, Matthias ^b   Krek, Wilhelm ^a,b  

^a FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH   (Switzerland)

^b ETH ZURICH   (Switzerland)

^c UNIVERSITÉ DE STRASBOURG   (France)

^d CNRS   (France)

Author keywords

[No Author keywords available]

Indexed keywords

GENES; PROTEINS; RNA; YEAST;

GENE EXPRESSION;

NUTRITION;

ADENOSINE TRIPHOSPHATASE; CHAPERONE; GLUTATHIONE TRANSFERASE; IMMUNOGLOBULIN G; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHOTRANSFERASE; PREFOLDIN; PROTEIN STAP1; RAPAMYCIN; RNA POLYMERASE; S PHASE KINASE ASSOCIATED PROTEIN 2; TARGET OF RAPAMYCIN KINASE; TRANSFER RNA; UNCLASSIFIED DRUG; UNCONVENTIONAL PREFOLDIN RPB5 INTERACTOR;

ARTICLE; EVOLUTION; GEL FILTRATION; GENE EXPRESSION; HELA CELL; HUMAN; MOLECULAR WEIGHT; NONHUMAN; NUTRIENT; NUTRITION; OPEN READING FRAME; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SACCHAROMYCES CEREVISIAE; SEQUENCE HOMOLOGY; TRANSCRIPTION REGULATION;

AMINO ACID SEQUENCE; AMINO ACIDS; CARRIER PROTEINS; CELL LINE; DNA-BINDING PROTEINS; DNA-DIRECTED RNA POLYMERASES; GATA TRANSCRIPTION FACTORS; GENE EXPRESSION REGULATION; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MOLECULAR SEQUENCE DATA; PHOSPHORYLATION; PROTEIN KINASES; PROTEIN SUBUNITS; REPRESSOR PROTEINS; RNA INTERFERENCE; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SIGNAL TRANSDUCTION; SIROLIMUS; TRANS-ACTIVATORS; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; TRANSFECTION;

SACCHAROMYCES; SACCHAROMYCES CEREVISIAE;

EID: 0242497664     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.1088401     Document Type: Article

References (26)

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26. We thank A. G. Hinnebusch for myc-GCN4 and lacZ-reporter plasmids; G. Thomas for mTOR plasmids: R. Agami for the pSUPER vector; J. Paszkowski, U. Müller, and G. Thomas for critical reading of the manuscript; and all members of our laboratory for discussions. Supported by the Swiss Cancer League, the Novartis Research Foundation, the Association pour la Recherche sur le Cancer (M.V.), and the Swiss National Science Foundation (M.P.).