메뉴 건너뛰기




Volumn 126, Issue 23, 1999, Pages 5365-5372

PTEN affects cell size, cell proliferation and apoptosis during Drosophila eye development

Author keywords

Apoptosis; Cell size; Drosophila development; Insulin signaling; Proliferation; PTEN tumor suppressor

Indexed keywords

INSULIN; INSULIN RECEPTOR;

EID: 0033376684     PISSN: 09501991     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (275)

References (51)
  • 2
    • 0027160708 scopus 로고
    • Targeted gene expression as a means of altering cell fates and generating dominant phenotypes
    • Brand, A. H. and Perrimon, N. (1993). Targeted gene expression as a means of altering cell fates and generating dominant phenotypes. Development 118, 401-415.
    • (1993) Development , vol.118 , pp. 401-415
    • Brand, A.H.1    Perrimon, N.2
  • 4
    • 0033551070 scopus 로고    scopus 로고
    • New insights into tumor suppression: PTEN suppresses tumor formation by restraining the phosphoinositide 3-kinase/AKT pathway
    • Cantley, L. C. and Neel, B. G. (1999). New insights into tumor suppression: PTEN suppresses tumor formation by restraining the phosphoinositide 3-kinase/AKT pathway. Proc. Natl. Acad. Sci. USA 96, 4240-4245.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 4240-4245
    • Cantley, L.C.1    Neel, B.G.2
  • 6
    • 0028803222 scopus 로고
    • Uncoupling cell fate determination from patterned cell division in the Drosophila eye
    • de Nooij, J. C. and Hariharan, I. K. (1995). Uncoupling cell fate determination from patterned cell division in the Drosophila eye [see comments]. Science 270, 983-985.
    • (1995) Science , vol.270 , pp. 983-985
    • De Nooij, J.C.1    Hariharan, I.K.2
  • 7
    • 0032176512 scopus 로고    scopus 로고
    • Protein tyrosine phosphatases: Mechanisms of catalysis and regulation
    • Denu, J. M. and Dixon, J. E. (1998). Protein tyrosine phosphatases: mechanisms of catalysis and regulation. Curr. Opin. Chem. Biol. 2, 633-641.
    • (1998) Curr. Opin. Chem. Biol. , vol.2 , pp. 633-641
    • Denu, J.M.1    Dixon, J.E.2
  • 8
    • 0030297891 scopus 로고    scopus 로고
    • Form and function in protein dephosphorylation
    • Denu, J. M., Stuckey, J. A., Saper, M. A. and Dixon, J. E. (1996). Form and function in protein dephosphorylation. Cell 87, 361-364.
    • (1996) Cell , vol.87 , pp. 361-364
    • Denu, J.M.1    Stuckey, J.A.2    Saper, M.A.3    Dixon, J.E.4
  • 9
    • 0031870959 scopus 로고    scopus 로고
    • Pten is essential for embryonic development and tumour suppression
    • Di Cristofano, A., Pesce, B., Cordon-Cardo, C. and Pandolfi, P. P. (1998). Pten is essential for embryonic development and tumour suppression. Nat. Genet. 19, 348-355.
    • (1998) Nat. Genet. , vol.19 , pp. 348-355
    • Di Cristofano, A.1    Pesce, B.2    Cordon-Cardo, C.3    Pandolfi, P.P.4
  • 11
    • 0030728479 scopus 로고    scopus 로고
    • Growth suppression of glioma cells by PTEN requires a functional phosphatase catalytic domain
    • Furnari, F. B., Lin, H., Huang, H. S. and Cavenee, W. K. (1997). Growth suppression of glioma cells by PTEN requires a functional phosphatase catalytic domain. Proc. Natl. Acad. Sci. USA 94, 12479-12484.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 12479-12484
    • Furnari, F.B.1    Lin, H.2    Huang, H.S.3    Cavenee, W.K.4
  • 12
    • 0032981396 scopus 로고    scopus 로고
    • Regulation of the insulin-like developmental pathway of Caenorhabditis elagans by a homolog of the PTEN tumor suppressor gene
    • Gil, E. B., Malone Link, E., Liu, L. X., Johnson, C. D. and Lees, J. A. (1999). Regulation of the insulin-like developmental pathway of Caenorhabditis elagans by a homolog of the PTEN tumor suppressor gene. Proc. Natl. Acad. Sci. USA 96, 2925-2930.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 2925-2930
    • Gil, E.B.1    Malone Link, E.2    Liu, L.X.3    Johnson, C.D.4    Lees, J.A.5
  • 13
    • 0033606767 scopus 로고    scopus 로고
    • Shc and FAK differentially regulate cell motility and directionality modulated by PTEN
    • Gu, J., Tamura, M., Pankov, R., Danen, E. H., Takino, T., Matsumoto, K. and Yamada, K. M. (1999). Shc and FAK differentially regulate cell motility and directionality modulated by PTEN. J. Cell Biol. 146, 389-403.
    • (1999) J. Cell Biol. , vol.146 , pp. 389-403
    • Gu, J.1    Tamura, M.2    Pankov, R.3    Danen, E.H.4    Takino, T.5    Matsumoto, K.6    Yamada, K.M.7
  • 14
    • 0030777104 scopus 로고    scopus 로고
    • Disruption of the MMAC1/PTEN gene by deletion or mutation is a frequent event in malignant melanoma
    • Guldberg, P., thor Straten, P., Birck, A., Ahrenkiel, V., Kirkin, A. F. and Zeuthen, J. (1997). Disruption of the MMAC1/PTEN gene by deletion or mutation is a frequent event in malignant melanoma. Cancer Res. 57, 3660-3663.
    • (1997) Cancer Res. , vol.57 , pp. 3660-3663
    • Guldberg, P.1    Thor Straten, P.2    Birck, A.3    Ahrenkiel, V.4    Kirkin, A.F.5    Zeuthen, J.6
  • 15
    • 0031819408 scopus 로고    scopus 로고
    • Eyeless initiates the expression of both sine oculis and eyes absent during Drosophila compound eye development
    • Halder, G., Callaerts, P., Flister, S., Walldorf, U., Kloter, U. and Gehring, W. J. (1998). Eyeless initiates the expression of both sine oculis and eyes absent during Drosophila compound eye development. Development 125, 2181-2191.
    • (1998) Development , vol.125 , pp. 2181-2191
    • Halder, G.1    Callaerts, P.2    Flister, S.3    Walldorf, U.4    Kloter, U.5    Gehring, W.J.6
  • 16
    • 0028141705 scopus 로고
    • Expression of baculovirus P35 prevents cell death in Drosophila
    • Hay, B. A., Wolff, T. and Rubin, G. M. (1994). Expression of baculovirus P35 prevents cell death in Drosophila. Development 120, 2121-2129.
    • (1994) Development , vol.120 , pp. 2121-2129
    • Hay, B.A.1    Wolff, T.2    Rubin, G.M.3
  • 17
    • 0029830237 scopus 로고    scopus 로고
    • The Drosophila phosphoinositide 3-kinase Dp1 10 promotes cell growth
    • Leevers, S. J., Weinkove, D., MacDougall, L. K., Hafen, E. and Waterfield, M. D. (1996). The Drosophila phosphoinositide 3-kinase Dp1 10 promotes cell growth. EMBO J. 15, 6584-6594.
    • (1996) EMBO J. , vol.15 , pp. 6584-6594
    • Leevers, S.J.1    Weinkove, D.2    MacDougall, L.K.3    Hafen, E.4    Waterfield, M.D.5
  • 18
    • 0031001041 scopus 로고    scopus 로고
    • TEP1, encoded by a candidate tumor suppressor locus, is a novel protein tyrosine phosphatase regulated by transforming growth factor beta
    • Li, D. M. and Sun, H. (1997). TEP1, encoded by a candidate tumor suppressor locus, is a novel protein tyrosine phosphatase regulated by transforming growth factor beta. Cancer Res. 57, 2124-2129.
    • (1997) Cancer Res. , vol.57 , pp. 2124-2129
    • Li, D.M.1    Sun, H.2
  • 19
    • 0032431028 scopus 로고    scopus 로고
    • 1 cell cycle arrest in human glioblastoma cells
    • 1 cell cycle arrest in human glioblastoma cells. Proc. Natl. Acad. Sci. USA 95, 15406-15411.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 15406-15411
    • Li, D.M.1    Sun, H.2
  • 20
    • 0032534963 scopus 로고    scopus 로고
    • The PTEN/MMAC1 tumor suppressor induces cell death that is rescued by the AKT/protein kinase B oncogene
    • Li, J., Simpson, L., Takahashi, M., Miliaresis, C., Myers, M. P., Tonks, N. and Parsons, R. (1998). The PTEN/MMAC1 tumor suppressor induces cell death that is rescued by the AKT/protein kinase B oncogene. Cancer Res. 58, 5667-5672.
    • (1998) Cancer Res. , vol.58 , pp. 5667-5672
    • Li, J.1    Simpson, L.2    Takahashi, M.3    Miliaresis, C.4    Myers, M.P.5    Tonks, N.6    Parsons, R.7
  • 21
    • 0030936323 scopus 로고    scopus 로고
    • PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer
    • Li, J., Yen, C., Liaw, D., Podsypanina, K., Bose, S., Wang, S. I., Puc, J., Miliaresis, C., Rodgers, L., McCombie, R. et al. (1997a). PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer [see comments]. Science 275, 1943-1947.
    • (1997) Science , vol.275 , pp. 1943-1947
    • Li, J.1    Yen, C.2    Liaw, D.3    Podsypanina, K.4    Bose, S.5    Wang, S.I.6    Puc, J.7    Miliaresis, C.8    Rodgers, L.9    McCombie, R.10
  • 22
    • 0030697429 scopus 로고    scopus 로고
    • A family of putative tumor suppressors is structurally and functionally conserved in humans and yeast
    • Li, L., Ernsting, B. R., Wishart, M. J., Lohse, D. L. and Dixon, J. E. (1997b). A family of putative tumor suppressors is structurally and functionally conserved in humans and yeast. J. Biol. Chem. 272, 29403-29406.
    • (1997) J. Biol. Chem. , vol.272 , pp. 29403-29406
    • Li, L.1    Ernsting, B.R.2    Wishart, M.J.3    Lohse, D.L.4    Dixon, J.E.5
  • 24
    • 0030724320 scopus 로고    scopus 로고
    • PTEN/MMAC1 mutations and EGFR amplification in glioblastomas
    • Liu, W., James, C. D., Frederick, L., Alderete, B. E. and Jenkins, R. B. (1997). PTEN/MMAC1 mutations and EGFR amplification in glioblastomas. Cancer Res. 57, 5254-5257.
    • (1997) Cancer Res. , vol.57 , pp. 5254-5257
    • Liu, W.1    James, C.D.2    Frederick, L.3    Alderete, B.E.4    Jenkins, R.B.5
  • 25
    • 0032577699 scopus 로고    scopus 로고
    • The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate
    • Maehama, T. and Dixon, J. E. (1998). The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate. J. Biol. Chem. 273, 13375-13378.
    • (1998) J. Biol. Chem. , vol.273 , pp. 13375-13378
    • Maehama, T.1    Dixon, J.E.2
  • 27
    • 0033595003 scopus 로고    scopus 로고
    • The PTEN tumor suppressor homolog in caenorhabditis elegans regulates longevity and dauer formation in an insulin receptor-like signaling pathway
    • Mihaylova, V. T., Borland, C. Z., Manjarrez, L., Stern, M. J. and Sun, H. (1999). The PTEN tumor suppressor homolog in Caenorhabditis elegans regulates longevity and dauer formation in an insulin receptor-like signaling pathway. Proc. Natl. Acad. Sci. USA 96, 7427-7432.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 7427-7432
    • Mihaylova, V.T.1    Borland, C.Z.2    Manjarrez, L.3    Stern, M.J.4    Sun, H.5
  • 30
    • 0031442631 scopus 로고    scopus 로고
    • PTEN: Sometimes taking it off can be better than putting it on
    • Myers, M. P. and Tonks, N. K. (1997). PTEN: sometimes taking it off can be better than putting it on. Am. J. Hum. Genet. 61, 1234-1238.
    • (1997) Am. J. Hum. Genet. , vol.61 , pp. 1234-1238
    • Myers, M.P.1    Tonks, N.K.2
  • 31
    • 0032568795 scopus 로고    scopus 로고
    • Coordination of growth and cell division in the Drosophila wing
    • Neufeld, T. P., de la Cruz, A. F., Johnston, L. A. and Edgar, B. A. (1998). Coordination of growth and cell division in the Drosophila wing. Cell 93, 1183-1193.
    • (1998) Cell , vol.93 , pp. 1183-1193
    • Neufeld, T.P.1    De La Cruz, A.F.2    Johnston, L.A.3    Edgar, B.A.4
  • 32
    • 0032238299 scopus 로고    scopus 로고
    • The C. Elegans PTEN homolog, DAF-18, acts in the insulin receptor-like metabolic signaling pathway
    • Ogg, S. and Ruvkun, G. (1998). The C. elegans PTEN homolog, DAF-18, acts in the insulin receptor-like metabolic signaling pathway. Mol. Cell 2, 887-893.
    • (1998) Mol. Cell , vol.2 , pp. 887-893
    • Ogg, S.1    Ruvkun, G.2
  • 36
    • 0025744938 scopus 로고
    • Characterization and spatial distribution ot the ELAV protein during Drasophila melanogaster development
    • Robinow, S. and White, K. (1991). Characterization and spatial distribution ot the ELAV protein during Drasophila melanogaster development. J. Neurobiol. 22, 443-461.
    • (1991) J. Neurobiol. , vol.22 , pp. 443-461
    • Robinow, S.1    White, K.2
  • 37
    • 0033602383 scopus 로고    scopus 로고
    • Regulation of dauer larva development in Caenorhabditis elegans by daf-18, a homologue of the tumour suppressor PTEN
    • Rouault, J. P., Kuwabara, P. E., Sinilnikova, O. M., Duret, L., Thierry-Mieg, D. and Billaud, M. (1999). Regulation of dauer larva development in Caenorhabditis elegans by daf-18, a homologue of the tumour suppressor PTEN. Curr. Biol. 9, 329-332.
    • (1999) Curr. Biol. , vol.9 , pp. 329-332
    • Rouault, J.P.1    Kuwabara, P.E.2    Sinilnikova, O.M.3    Duret, L.4    Thierry-Mieg, D.5    Billaud, M.6
  • 38
    • 84861107941 scopus 로고
    • Cell death during the development of the imaginal discs of Calliphora erythrocephala
    • Spreij, T. E. (1971). Cell death during the development of the imaginal discs of Calliphora erythrocephala. Netherlands J. Zool. 21, 221-264.
    • (1971) Netherlands J. Zool. , vol.21 , pp. 221-264
    • Spreij, T.E.1
  • 41
    • 13044305289 scopus 로고    scopus 로고
    • PTEN modulates cell cycle progression and cell survival by regulating phosphatidylinositol 3,4,5,-trisphosphate and Akt/protein kinase B signaling pathway
    • Sun, H., Lesche, R., Li, D. M., Liliental, J., Zhang, H., Gao, J., Gavrilova, N., Mueller, B., Liu, X. and Wu, H. (1999). PTEN modulates cell cycle progression and cell survival by regulating phosphatidylinositol 3,4,5,-trisphosphate and Akt/protein kinase B signaling pathway. Proc. Natl. Acad. Sci. USA 96, 6199-6204.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 6199-6204
    • Sun, H.1    Lesche, R.2    Li, D.M.3    Liliental, J.4    Zhang, H.5    Gao, J.6    Gavrilova, N.7    Mueller, B.8    Liu, X.9    Wu, H.10
  • 43
    • 0032486198 scopus 로고    scopus 로고
    • Inhibition of cell migration, spreading, and focal adhesions by tumor suppressor PTEN
    • Tamura, M., Gu, J., Matsumoto, K., Aota, S., Parsons, R. and Yamada, K. M. (1998). Inhibition of cell migration, spreading, and focal adhesions by tumor suppressor PTEN. Science 280, 1614-1617.
    • (1998) Science , vol.280 , pp. 1614-1617
    • Tamura, M.1    Gu, J.2    Matsumoto, K.3    Aota, S.4    Parsons, R.5    Yamada, K.M.6
  • 44
    • 0032954260 scopus 로고    scopus 로고
    • Human homologue of the Drosophila melanogaster lats tumour suppressor modulates CDC2 activity
    • Tao, W., Zhang, S., Turenchalk, G. S., Stewart, R. A., St John, M. A., Chen, W. and Xu, T. (1999). Human homologue of the Drosophila melanogaster lats tumour suppressor modulates CDC2 activity. Nat. Genet. 21, 177-181.
    • (1999) Nat. Genet. , vol.21 , pp. 177-181
    • Tao, W.1    Zhang, S.2    Turenchalk, G.S.3    Stewart, R.A.4    St John, M.A.5    Chen, W.6    Xu, T.7
  • 45
    • 0030761409 scopus 로고    scopus 로고
    • Mutations in PTEN are frequent in endometrial carcinoma but rare in other common gynecological malignancies
    • Tashiro, H., Blazes, M. S., Wu, R., Cho, K. R., Bose, S., Wang, S. I., Li, J., Parsons, R. and Ellensun, L. H. (1997). Mutations in PTEN are frequent in endometrial carcinoma but rare in other common gynecological malignancies. Cancer Res. 57, 3935-3940.
    • (1997) Cancer Res. , vol.57 , pp. 3935-3940
    • Tashiro, H.1    Blazes, M.S.2    Wu, R.3    Cho, K.R.4    Bose, S.5    Wang, S.I.6    Li, J.7    Parsons, R.8    Ellensun, L.H.9
  • 46
    • 0031671351 scopus 로고    scopus 로고
    • Slimb coordinates wg and dpp expression in the dorsal-ventral and anterior-posterior axes during limb development
    • Theodosiou, N. A., Zhang, S., Wang, W. Y. and Xu, T. (1998). slimb coordinates wg and dpp expression in the dorsal-ventral and anterior-posterior axes during limb development. Development 125, 3411-3416.
    • (1998) Development , vol.125 , pp. 3411-3416
    • Theodosiou, N.A.1    Zhang, S.2    Wang, W.Y.3    Xu, T.4
  • 48
    • 0030021282 scopus 로고    scopus 로고
    • Cell killing by the Drosophila gene reaper
    • White, K., Tahaoglu, E. and Steller, H. (1996). Cell killing by the Drosophila gene reaper. Science 271, 805-807.
    • (1996) Science , vol.271 , pp. 805-807
    • White, K.1    Tahaoglu, E.2    Steller, H.3
  • 49
    • 0025995598 scopus 로고
    • Cell death in normal and rough eye mutants of Drosophila
    • Wolff, T. and Ready, D. F. (1991). Cell death in normal and rough eye mutants of Drosophila. Development 113, 825-839.
    • (1991) Development , vol.113 , pp. 825-839
    • Wolff, T.1    Ready, D.F.2
  • 50
    • 0028695434 scopus 로고
    • Mosaic analysis using FLP recombinase
    • Xu, T. and Harrison, S. D. (1994). Mosaic analysis using FLP recombinase. Meth. Cell Biol. 44, 655-681.
    • (1994) Meth. Cell Biol. , vol.44 , pp. 655-681
    • Xu, T.1    Harrison, S.D.2
  • 51
    • 0028929414 scopus 로고
    • Identifying tumor suppressors in genetic mosaics: The Drosophila lats gene encodes a putative protein kinase
    • Xu, T., Wang, W., Zhang, S., Stewart, R. A. and Yu, W. (1995). Identifying tumor suppressors in genetic mosaics: the Drosophila lats gene encodes a putative protein kinase. Development 121, 1053-1063.
    • (1995) Development , vol.121 , pp. 1053-1063
    • Xu, T.1    Wang, W.2    Zhang, S.3    Stewart, R.A.4    Yu, W.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.