Targeted disruption of p70s6k defines its role in protein synthesis and rapamycin sensitivity

Proceedings of the National Academy of Sciences of the United States of America

Volumn 95, Issue 9, 1998, Pages 5033-5038

  Kawasome, Hideki ^a   Papst, Philip ^a   Webb, Saiphone ^a   Keller, Gordon M ^a   Johnson, Gary L ^a   Gelfand, Erwin W ^a   Terada, Naohiro ^a  

^a NATIONAL JEWISH MEDICAL AND RESEARCH CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MURINAE; ANIMALIA; RODENTIA;

PROTEIN SERINE THREONINE KINASE; RAPAMYCIN;

ANIMAL CELL; ARTICLE; CELL GROWTH; CELL PROLIFERATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS; RNA TRANSLATION;

AMINO ACID SEQUENCE; ANIMALS; CARRIER PROTEINS; CELL DIVISION; MICE; MOLECULAR SEQUENCE DATA; MUTAGENESIS, INSERTIONAL; PHOSPHOPROTEINS; PHOSPHORYLATION; POLYENES; PROTEIN BIOSYNTHESIS; RIBOSOMAL PROTEIN S6; RIBOSOMAL PROTEIN S6 KINASES; RIBOSOMAL PROTEINS; RNA, MESSENGER; SIROLIMUS;

EID: 0032574823     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.95.9.5033     Document Type: Article

References (42)

1. Brown, E. J. & Schreiber, S. L. (1996) Cell 86, 517-520.
2. Blenis, J., Kuo, C. J. & Erikson, R. L. (1987) J. Biol. Chem. 262, 14373-14376.
3. Jeno, P., Ballou, L. M., Novak-Hofer, I. & Thomas, G. (1988) Proc. Natl. Acad. Sci. USA 85, 406-410.
4. Price, D. J., Nemenoff, R. A. & Avruch, J. (1989) J. Biol. Chem. 264, 13825-13833.
5. Ballou, L. M., Luther, H. & Thomas, G. (1991) Nature (London) 349, 348-350.
6. Blenis, J., Chung, J., Erikson, E., Alcorta, D. A. & Erikson, R. L. (1991) Cell Growth Differ. 2, 279-285.
7. Calvo, V., Crews, C. M., Vik, T. A. & Bierer, B. E. (1992) Proc. Natl. Acad. Sci. USA 89, 7571-7575.
8. Chung, J., Kuo, C. J., Crabtree, G. R. & Blenis, J. (1992) Cell 69, 1227-1236.
9. Kuo, C. J., Chung, J., Fiorentino, D. F., Flanagan, W. M., Blenis, J. & Crabtree, G. R. (1992) Nature (London) 358, 70-73.
10. Price, D. J., Grove, J. R., Calvo, V., Avruch, J. & Bierer, B. E. (1992) Science 257, 973-977.
11. Terada, N., Lucas, J. J., Szepesi, A., Franklin, R. A., Takase, K. & Gelfand, E. W. (1992) Biochem. Biophys. Res. Commun. 186, 1315-1321.
12. Terao, K. & Ogata, K. (1979) J. Biochem. 86, 597-603.
13. Bommer, U.-A., Noll, F., Lutsch, G. & Bielka, H. (1980) FEBS Lett. 111, 171-174.
14. Tolan, D. R. & Traut, R. R. (1981) J. Biol. Chem. 256, 10129-10136.
15. Kozma, S. C., Ferrari, S. & Thomas, G. (1989) Cell Signalling 3, 219-225.
16. Proud, C. G. (1992) Curr. Top. Cell. Regul. 32, 243-369.
17. Brown, E. J., Beal, P. A., Keith, C. T., Chen, J., Shin, T. B. & Schreiher, S. L. (1996) Nature (London) 377, 441-446.
18. Jefferies, H. B. J., Reinhard, C., Kozma, S. C. & Thomas, G. (1994) Proc. Natl. Acad. Sci. USA 91, 4441-4445.
19. Terada, N., Patel, H. R., Takase, K., Kohno, K., Nairn, A. C. & Gelfand, E. W. (1994) Proc. Natl. Acad. Sci. USA 91, 11477-11481.
20. Nourse, J., Firpo, E., Flanagan, W. M., Coats, S., Polyak, K., Lee, M.-H., Massague, J., Crabtree, G. R. & Roberts, J. M. (1994) Nature (London) 372, 570-573.
21. Kato, J., Matsuoka, M., Polyak, K., Massague, J. & Sherr, C. J. (1994) Cell 79, 487-496.
22. de Groot, R. P., Ballou, L. M. & Sassonc-Corsi, P. (1994) Cell 79, 81-91.
23. Beretta, L., Gingras, A.-C., Svitkin, Y. V., Hall, M. N. & Sonenberg, N (1996) EMBO J. 15, 658-664.
24. von Manteuffel, S. R., Gingras, A.-C., Ming, X.-F., Sonenberg, N. & Thomas, G. (1996) Proc. Natl. Acad. Sci. USA 93, 4076-4080.
25. Rudnicki, M. A., Braun, T., Hinuma, S. & Jaenisch, R. (1992) Cell 71, 383-390.
26. Hogan, B. (1994) Manipulating the Mouse Embryo (Cold Spring Harbor Lab. Press, New York).
27. Mortensen, R. M., Conner, D. A., Chao, S., Geisterfer-Lowrance, A. A. T. & Seidman, J. G. (1992) Mol. Cell. Biol. 12, 2391-2395.
28. Brunn, G. J., Hudson, C. C., Sekulic, A., Williams, J. M., Hosoi, H., Houghton, P. J., Lawrence, J. C., Jr., & Abraham, R. T. (1997) Science 277, 99-101.
29. Terada, N., Takase, K., Papst, P., Nairn, A. C. & Gelfand, E. W. (1995) J. Immunol. 155, 3418-3426.
30. Patel, H. R., Terada, N. & Gelfand, E. W. (1996) Biochem. Biophys. Res. Commun. 227, 507-512.
31. Grove, J. R., Banerjee, P., Balasubramanyam, A., Coffer, P. J., Price, D. J., Avruch, J. & Woodgett, J. R. (1991) Mol. Cell. Biol. 11, 5541-5550.
32. Reinhard, C., Thomas, G. & Kozma, S. C. (1992) Proc. Natl. Acad. Sci. USA 89, 4052-4056.
33. Reinhard, C., Fernandez, A., Lamb, N. J. C. & Thomas, G. (1994) EMBO J. 13, 1557-1565.
34. Susa, M., Olivier, A. R., Fabbro, D. & Thomas, G. (1989) Cell 57, 817-824.
35. Terada, N., Franklin, R. A., Lucas, J. J., Blenis, J. & Gelfand, E. W. (1993) J. Biol. Chem. 268, 12062-12068.
36. Lane, H. A., Fernandez, A., Lamb, N. J. C. & Thomas, G. (1993) Nature (London) 363, 170-172.
37. von Manteuffel, S. R., Dennis, P. B., Pullen, N., Gingras, A.-C., Sonenberg, N. & Thomas, G. (1997) Mol. Cell. Biol. 17, 5426-5436.
38. Jefferies, H. B. J., Fumagalli, S., Dennis, P. B., Reinhard, C., Pearson, R. B. & Thomas, G. (1997) EMBO J. 16, 3693-3704.
39. Lewin, B. (1994) Genes V (Oxford Univ. Press, Oxford).
40. Baughman, G. & Nomura, M. (1983) Cell 34, 979-988.
41. Hammond, M. L. & Bowman, L. H. (1988) J. Biol. Chem. 263, 17785-17791.
42. Mahajan, P. B. (1994) Int. J. Immunopharmacol. 16, 711-721.