-
1
-
-
0023849673
-
Protein phosphatase 2A inactivates the mitogen-stimulated S6 kinase from Swiss mouse 3T3 cells
-
Ballou, L. M., P. Jeno, and G. Thomas. 1988. Protein phosphatase 2A inactivates the mitogen-stimulated S6 kinase from Swiss mouse 3T3 cells. J Biol. Chem. 263:1188-1194.
-
(1988)
J Biol. Chem.
, vol.263
, pp. 1188-1194
-
-
Ballou, L.M.1
Jeno, P.2
Thomas, G.3
-
2
-
-
0026100595
-
MAP2 kinase and 70K S6 kinase lie on distinct signalling pathwavs
-
Ballou, L. M., H. Luther, and G. Thomas, 1991. MAP2 kinase and 70K S6 kinase lie on distinct signalling pathwavs. Nature (London) 349:348-350.
-
(1991)
Nature (London)
, vol.349
, pp. 348-350
-
-
Ballou, L.M.1
Luther, H.2
Thomas, G.3
-
3
-
-
0028360374
-
A mammalian protein targeted by G1-arresting rapamycin-receptor complex
-
Brown, E. J., M. W. Albers, T. B. Shin, K. Ichikawa, C. T. Keith, W. S. Lane, and S. L. Schreiber. 1994. A mammalian protein targeted by G1-arresting rapamycin-receptor complex. Nature (London) 369:756-758.
-
(1994)
Nature (London)
, vol.369
, pp. 756-758
-
-
Brown, E.J.1
Albers, M.W.2
Shin, T.B.3
Ichikawa, K.4
Keith, C.T.5
Lane, W.S.6
Schreiber, S.L.7
-
4
-
-
0026666050
-
Interleukin 2 stimulation of p70 S6 kinase activity is inhibited by the immunosuppressant rapamycin
-
Calvo, V., C. M. Crews, T. A. Vik, and B. E. Bierer. 1992. Interleukin 2 stimulation of p70 S6 kinase activity is inhibited by the immunosuppressant rapamycin Proc. Natl. Acad. Sci. USA 89:7571-7575.
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 7571-7575
-
-
Calvo, V.1
Crews, C.M.2
Vik, T.A.3
Bierer, B.E.4
-
5
-
-
0028308412
-
Phosphatidylinositol 3-kinase activation is required for insulin stimulation of pp70 S6 kinase. DNA synthesis, and glucose transporter translocation
-
Cbeatham, B., C. J. Vlahos, L. Cheatham, L. Wang, J. Blenis, and C. R. Kahn. 1994. Phosphatidylinositol 3-kinase activation is required for insulin stimulation of pp70 S6 kinase. DNA synthesis, and glucose transporter translocation. Mol. Cell Biol. 14:4902-4911
-
(1994)
Mol. Cell Biol.
, vol.14
, pp. 4902-4911
-
-
Cbeatham, B.1
Vlahos, C.J.2
Cheatham, L.3
Wang, L.4
Blenis, J.5
Kahn, C.R.6
-
6
-
-
0026608787
-
Nuclear localization and regulation of erk- and rsk-encoded protein kinases
-
Chen, R. H., C. Sarnecki, and J. Blenis. 1992. Nuclear localization and regulation of erk- and rsk-encoded protein kinases. Mol. Cell. Biol. 12:915-927
-
(1992)
Mol. Cell. Biol.
, vol.12
, pp. 915-927
-
-
Chen, R.H.1
Sarnecki, C.2
Blenis, J.3
-
7
-
-
0028178928
-
PDGF- and insulin-dependent pp70S6k activation mediated by phosphatidylinositol-3-OH kinase
-
Chung, J., T. C. Grammer, K. P. Lemon, A. Kazlauskas, and J. Blenis. 1994. PDGF- and insulin-dependent pp70S6k activation mediated by phosphatidylinositol-3-OH kinase. Nature (London) 370:71-75
-
(1994)
Nature (London)
, vol.370
, pp. 71-75
-
-
Chung, J.1
Grammer, T.C.2
Lemon, K.P.3
Kazlauskas, A.4
Blenis, J.5
-
8
-
-
0026659046
-
Rapamycin-FKBP specifically blocks growth-dependent activation of and signaling by the 70 kd S6 protein kinases
-
Chung, J., C. J. Kuo, G. R. Crabtree, and J. Blenis. 1992. Rapamycin-FKBP specifically blocks growth-dependent activation of and signaling by the 70 kd S6 protein kinases. Cell 69:1227-1236.
-
(1992)
Cell
, vol.69
, pp. 1227-1236
-
-
Chung, J.1
Kuo, C.J.2
Crabtree, G.R.3
Blenis, J.4
-
9
-
-
0028928611
-
The chemistry of signal transduction
-
Clardy, J. 1995. The chemistry of signal transduction. Proc. Natl. Acad. Sci. USA 92:56-61.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 56-61
-
-
Clardy, J.1
-
10
-
-
0028276966
-
Differential subcellular localisation of two isoforms of p70 S6 protein kinase
-
Coffer, P. J., and J. R. Woodgett. 1994 Differential subcellular localisation of two isoforms of p70 S6 protein kinase. Biochem. Biophys Res. Commun 198:780-786.
-
(1994)
Biochem. Biophys Res. Commun
, vol.198
, pp. 780-786
-
-
Coffer, P.J.1
Woodgett, J.R.2
-
11
-
-
0027983480
-
Positive regulation of the cAMP-responsive activator CREM by the p70 S6 kinase: An alternative route to mitogen-induced gene expression
-
de Groot, R. P., L. M. Ballou, and P. Sassone-Corsi. 1994. Positive regulation of the cAMP-responsive activator CREM by the p70 S6 kinase: an alternative route to mitogen-induced gene expression. Cell 79:81-91.
-
(1994)
Cell
, vol.79
, pp. 81-91
-
-
De Groot, R.P.1
Ballou, L.M.2
Sassone-Corsi, P.3
-
12
-
-
0025155473
-
Cytoplasmic expression system based on constitutive synthesis of bacteriophage T7 RNA polymerase in mammalian cells
-
Elroy-Stein, O., and B. Moss. 1990. Cytoplasmic expression system based on constitutive synthesis of bacteriophage T7 RNA polymerase in mammalian cells. Proc. Natl. Acad. Sci. USA 87:6743-6747.
-
(1990)
Proc. Natl. Acad. Sci. USA
, vol.87
, pp. 6743-6747
-
-
Elroy-Stein, O.1
Moss, B.2
-
13
-
-
0025837327
-
Mitogen-activated 70K S6 kinase: Identification of in vitro 40 S ribosomal S6 phosphorylation sites
-
Ferrari, S., H. R. Bandi, J. Hofsteenge, B. M. Bussian, and G. Thomas. 1991. Mitogen-activated 70K S6 kinase: identification of in vitro 40 S ribosomal S6 phosphorylation sites J Biol. Chem 266:22770-22775.
-
(1991)
J Biol. Chem
, vol.266
, pp. 22770-22775
-
-
Ferrari, S.1
Bandi, H.R.2
Hofsteenge, J.3
Bussian, B.M.4
Thomas, G.5
-
14
-
-
0027228165
-
The immunosuppressant rapamycin induces motivation of p70s6k through dephosphorylation of a novel set of sites
-
Ferrari, S., R. B. Pearson, M. Siegmann, S. C. Kozma, and G. Thomas. 1993. The immunosuppressant rapamycin induces motivation of p70s6k through dephosphorylation of a novel set of sites J. Biol. Chem 268:16091-10094.
-
(1993)
J. Biol. Chem
, vol.268
, pp. 16091-110094
-
-
Ferrari, S.1
Pearson, R.B.2
Siegmann, M.3
Kozma, S.C.4
Thomas, G.5
-
15
-
-
0029079275
-
The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phos phatidylinositol 3-kinase
-
Franke, T. F., S.-I. Yang, T. O. Chan, K. Datta, A. Kazlauskas, D. K. Morrison, D. R. Kaplan, and P. N. Tsichlis. 1995. The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phos phatidylinositol 3-kinase Cell 81:727-736.
-
(1995)
Cell
, vol.81
, pp. 727-736
-
-
Franke, T.F.1
Yang, S.-I.2
Chan, T.O.3
Datta, K.4
Kazlauskas, A.5
Morrison, D.K.6
Kaplan, D.R.7
Tsichlis, P.N.8
-
16
-
-
0000233999
-
Eukaryotic transient-expression system based on recombinant vaccinia virus that synthesizes bacteriophage T7 RNA polymerase
-
Fuerst, T. R., E. G. Niles, F. W. Studier, and B. Moss. 1986 Eukaryotic transient-expression system based on recombinant vaccinia virus that synthesizes bacteriophage T7 RNA polymerase. Proc Natl. Acad. Sci USA 83:8122-8126.
-
(1986)
Proc Natl. Acad. Sci USA
, vol.83
, pp. 8122-8126
-
-
Fuerst, T.R.1
Niles, E.G.2
Studier, F.W.3
Moss, B.4
-
17
-
-
0028137771
-
TOR1 and TOR2 are structurally and functionally similar but not identical phosphatidylinositol kinase homologues in yeast
-
Helliwell, S. B., P. Wagner, J. Kunz, M. Deuter-Reinhard, R. Henriquez, and M. N. Hall. 1994. TOR1 and TOR2 are structurally and functionally similar but not identical phosphatidylinositol kinase homologues in yeast. Mol Biol. Cell 5:105-118.
-
(1994)
Mol Biol. Cell
, vol.5
, pp. 105-118
-
-
Helliwell, S.B.1
Wagner, P.2
Kunz, J.3
Deuter-Reinhard, M.4
Henriquez, R.5
Hall, M.N.6
-
18
-
-
0024797894
-
Protein phosphorylation controls translation rates
-
Hershey, J. W. 1989 Protein phosphorylation controls translation rates J Biol Chem. 264:20823-20836.
-
(1989)
J Biol Chem.
, vol.264
, pp. 20823-20836
-
-
Hershey, J.W.1
-
19
-
-
0028207001
-
Rapamycin selectively represses translation of the "polypyrimidine tract" mRNA family
-
Jefferies, H. B., C. Reinhard, S. C. Kozina, and G. Thomas. 1994 Rapamycin selectively represses translation of the "polypyrimidine tract" mRNA family. Proc. Natl. Acad Sci. USA 91:4441-4445.
-
(1994)
Proc. Natl. Acad Sci. USA
, vol.91
, pp. 4441-4445
-
-
Jefferies, H.B.1
Reinhard, C.2
Kozina, S.C.3
Thomas, G.4
-
20
-
-
0023673241
-
Identification and characterization of a mitogen-activated S6 kinase
-
Jeno, P., L. M. Ballou, I. Novak-Hofer, and G. Thomas. 1988. Identification and characterization of a mitogen-activated S6 kinase. Proc. Natl. Acad, Sci. USA 85:406-410.
-
(1988)
Proc. Natl. Acad, Sci. USA
, vol.85
, pp. 406-410
-
-
Jeno, P.1
Ballou, L.M.2
Novak-Hofer, I.3
Thomas, G.4
-
21
-
-
0029039957
-
Interleukin-2 triggers a novel phosphatidylinositol 3-kinase-dependent MEK activation pathway
-
Karnitz, L. M., L. A. Burns, S. L. Sutor, J. Blenis, and R. T. Abraham. 1995. Interleukin-2 triggers a novel phosphatidylinositol 3-kinase-dependent MEK activation pathway Mol. Cell. Biol. 15:3049-3057.
-
(1995)
Mol. Cell. Biol.
, vol.15
, pp. 3049-3057
-
-
Karnitz, L.M.1
Burns, L.A.2
Sutor, S.L.3
Blenis, J.4
Abraham, R.T.5
-
22
-
-
0027311858
-
Target of rapamycin in yeast, TOR2, is an essential phosphatidylinositol kinase homolog required for G1 progression
-
Kunz, J., R. Henriquez, U. Schneider, M. Deuter-Reinhard, N. R. Movva, and M. N. Hall. 1993. Target of rapamycin in yeast, TOR2, is an essential phosphatidylinositol kinase homolog required for G1 progression. Cell 73: 585-596.
-
(1993)
Cell
, vol.73
, pp. 585-596
-
-
Kunz, J.1
Henriquez, R.2
Schneider, U.3
Deuter-Reinhard, M.4
Movva, N.R.5
Hall, M.N.6
-
23
-
-
0026721092
-
Rapamycin selectively inhibits interleukin-2 activation of p70 S6 kinase
-
Kuo, C. J., J. Chung, D. F. Fiorentino, W. M. Flanagan, J. Blenis, and G. R. Crabtree. 1992. Rapamycin selectively inhibits interleukin-2 activation of p70 S6 kinase. Nature (London) 358:70-73.
-
(1992)
Nature (London)
, vol.358
, pp. 70-73
-
-
Kuo, C.J.1
Chung, J.2
Fiorentino, D.F.3
Flanagan, W.M.4
Blenis, J.5
Crabtree, G.R.6
-
24
-
-
0027336002
-
p70s6k function is essential for G1 progression
-
Lane, H. A., A. Fernandez, N. J. Lamb, and G. Thomas. 1993. p70s6k function is essential for G1 progression. Nature (London) 363:170-172.
-
(1993)
Nature (London)
, vol.363
, pp. 170-172
-
-
Lane, H.A.1
Fernandez, A.2
Lamb, N.J.3
Thomas, G.4
-
26
-
-
0029257493
-
Evidence that SH2 domains promote processive phosphorylation by protein-tyrosine kinases
-
Mayer, B. J., H. Hirai, and R. Sakai. 1995. Evidence that SH2 domains promote processive phosphorylation by protein-tyrosine kinases. Curr. Biol 5:296-305.
-
(1995)
Curr. Biol
, vol.5
, pp. 296-305
-
-
Mayer, B.J.1
Hirai, H.2
Sakai, R.3
-
27
-
-
0028168073
-
Activation of p70/p85 S6 kinase by a pathway independent of p21ras
-
Ming, X. F., B. M. Burgering, S. Wennstrom, L. Claesson-Welsh, C. H. Heldin, J. L. Bos, S. C. Kozma, and G. Thomas. 1994. Activation of p70/p85 S6 kinase by a pathway independent of p21ras [sec comments]. Nature (London) 371:426-429.
-
(1994)
Nature (London)
, vol.371
, pp. 426-429
-
-
Ming, X.F.1
Burgering, B.M.2
Wennstrom, S.3
Claesson-Welsh, L.4
Heldin, C.H.5
Bos, J.L.6
Kozma, S.C.7
Thomas, G.8
-
28
-
-
0025352187
-
Advanced mammalian gene transfer, high titre retroviral vectors with multiple drug selection markers and a complementary helper-free packaging cell line
-
Morgenstern, J. P., and H. Land. 1990. Advanced mammalian gene transfer, high titre retroviral vectors with multiple drug selection markers and a complementary helper-free packaging cell line. Nucleic Acids Res. 18:3587-3596.
-
(1990)
Nucleic Acids Res.
, vol.18
, pp. 3587-3596
-
-
Morgenstern, J.P.1
Land, H.2
-
29
-
-
0027749145
-
The mitogen activated S6 kinase: Sites of phosphorylation which lead to activation and identification of a putative kinase kinase
-
Morley, S. J., S. Ferrari, and G. Thomas. 1993. The mitogen activated S6 kinase: sites of phosphorylation which lead to activation and identification of a putative kinase kinase. Biochem Soc. Trans 21:3965.
-
(1993)
Biochem Soc. Trans
, vol.21
, pp. 3965
-
-
Morley, S.J.1
Ferrari, S.2
Thomas, G.3
-
30
-
-
0025513605
-
Product review: New mammalian expression vectors
-
Moss, B., O. Elroy-Stein, T. Mizukami, W. A. Alexander, and T. R. Fuerst. 1990. Product review: new mammalian expression vectors. Nature (London) 348:91-92.
-
(1990)
Nature (London)
, vol.348
, pp. 91-92
-
-
Moss, B.1
Elroy-Stein, O.2
Mizukami, T.3
Alexander, W.A.4
Fuerst, T.R.5
-
31
-
-
0025948372
-
Insulin-activated protein kinases phosphorylate a pseudosubstrate synthetic peptide inhibitor of the p70 S6 kinase
-
Price, D. J., N. K. Mukhopadhyay, and J. Avruch. 1991. Insulin-activated protein kinases phosphorylate a pseudosubstrate synthetic peptide inhibitor of the p70 S6 kinase. J. Biol. Chem 266:16281-16284
-
(1991)
J. Biol. Chem
, vol.266
, pp. 16281-16284
-
-
Price, D.J.1
Mukhopadhyay, N.K.2
Avruch, J.3
-
32
-
-
0026440512
-
Biological function of the retinoblastoma protein requires distinct domains for hyperphosphorylation and transcription factor binding
-
Qian, Y., C. Luckey, L. Horton, M. Esser, and D. J. Templeton. 1992. Biological function of the retinoblastoma protein requires distinct domains for hyperphosphorylation and transcription factor binding. Mol Cell. Biol 12:5363-5372.
-
(1992)
Mol Cell. Biol
, vol.12
, pp. 5363-5372
-
-
Qian, Y.1
Luckey, C.2
Horton, L.3
Esser, M.4
Templeton, D.J.5
-
33
-
-
0028175455
-
Nuclear localization of p85S6K: Functional requirement for entry into S phase
-
Reinhard, C., A. Fernandez, N. J. C. Lamb, and G. Thomas. 1994 Nuclear localization of p85S6K: functional requirement for entry into S phase. EMBO J. 13:1557-1565.
-
(1994)
EMBO J.
, vol.13
, pp. 1557-1565
-
-
Reinhard, C.1
Fernandez, A.2
Lamb, N.J.C.3
Thomas, G.4
-
34
-
-
0028239893
-
RAFT1: A mammalian protein that binds to FKBP12 in a rapamycin-dependent fashion and is homologous to yeast TORs
-
Sabatini, D. M., H. Erdjument-Bromage, M. Lui, P. Tempst, and S. H. Snyder. 1994 RAFT1: a mammalian protein that binds to FKBP12 in a rapamycin-dependent fashion and is homologous to yeast TORs Cell 78: 35-13.
-
(1994)
Cell
, vol.78
, pp. 35-113
-
-
Sabatini, D.M.1
Erdjument-Bromage, H.2
Lui, M.3
Tempst, P.4
Snyder, S.H.5
-
35
-
-
0028950217
-
Isolation of a protein target of the FKBP12-rapamycin complex in mammalian cells
-
Sabers, C. J., M. M. Martin, G. J. Brunn, J. M. Williams, F. J. Dumont, G. Wiederrecht, and R. T. Abraham. 1995. Isolation of a protein target of the FKBP12-rapamycin complex in mammalian cells. J Biol. Chem. 270:815-822.
-
(1995)
J Biol. Chem.
, vol.270
, pp. 815-822
-
-
Sabers, C.J.1
Martin, M.M.2
Brunn, G.J.3
Williams, J.M.4
Dumont, F.J.5
Wiederrecht, G.6
Abraham, R.T.7
-
36
-
-
0025325983
-
The "megaprimer" method of site-directed mutagenesis
-
Sarkar, G., and S. S. Sommer. 1990 The "megaprimer" method of site-directed mutagenesis. Biotechniques 8:404-407.
-
(1990)
Biotechniques
, vol.8
, pp. 404-407
-
-
Sarkar, G.1
Sommer, S.S.2
-
37
-
-
0026969189
-
Rapamycin inhibits the phosphorylation of p70 S6 kinase in IL-2 and mitogen-activated human T cells
-
Terada, N., J. J. Lucas, A. Szepesi, R. A. Franklin, K. Takase, and E. W. Gelfand. 1992 Rapamycin inhibits the phosphorylation of p70 S6 kinase in IL-2 and mitogen-activated human T cells. Biochem Biophys Res. Commun. 186:1315-1321.
-
(1992)
Biochem Biophys Res. Commun.
, vol.186
, pp. 1315-1321
-
-
Terada, N.1
Lucas, J.J.2
Szepesi, A.3
Franklin, R.A.4
Takase, K.5
Gelfand, E.W.6
-
38
-
-
0028939115
-
Multiple independent inputs are required for activation of the p70 S6 kinase
-
Weng, Q.-P., K. Andrabi, M. T. Kozlowski, J. R. Grove, and J. Avruch. 1995 Multiple independent inputs are required for activation of the p70 S6 kinase. Mol. Cell. Biol 15:2333-2340
-
(1995)
Mol. Cell. Biol
, vol.15
, pp. 2333-2340
-
-
Weng, Q.-P.1
Andrabi, K.2
Kozlowski, M.T.3
Grove, J.R.4
Avruch, J.5
|