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Proceedings of the National Academy of Sciences of the United States of America

Volumn 98, Issue 18, 2001, Pages 10314-10319

Enhanced sensitivity of PTEN-deficient tumors to inhibition of FRAP/mTOR

(10) Neshat, Mehran S a,b Mellinghoff, Ingo K a Tran, Chris a Stiles, Bangyan b Thomas, George a Petersen, Roseann c Frost, Philip c Gibbons, James J c Wu, Hong a,b Sawyers, Charles L a,b

a UNIVERSITY OF CALIFORNIA (United States)

b UNIVERSITY OF CALIFORNIA (United States)

c PFIZER INC (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MAMMALIAN TARGET OF RAPAMYCIN; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN KINASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER CELL; CARCINOGENESIS; CONTROLLED STUDY; CORRELATION FUNCTION; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DEFICIENCY; PROTEIN PHOSPHORYLATION; TUMOR; TUMOR GROWTH;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; CARRIER PROTEINS; CELLS, CULTURED; HUMANS; IMMUNOPHILINS; MALE; MICE; MICE, KNOCKOUT; MICE, NUDE; MICE, SCID; NEOPLASMS, EXPERIMENTAL; PHOSPHOPROTEINS; PHOSPHORIC MONOESTER HYDROLASES; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR); PROTEIN KINASE INHIBITORS; PROTEIN KINASES; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; PTEN PHOSPHOHYDROLASE; RATS; RIBOSOMAL PROTEIN S6 KINASES; SIROLIMUS; TUMOR CELLS, CULTURED; TUMOR SUPPRESSOR PROTEINS;

ANIMALIA;

EID: 17944377486 PISSN: 00278424 EISSN: None Source Type: Journal
DOI: 10.1073/pnas.171076798 Document Type: Article

Times cited : (924)

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