-
1
-
-
33847035824
-
Phosphorylation of HuR by Chk2 regulates SIRT1 expression
-
COI: 1:CAS:528:DC%2BD2sXjtlWkurg%3D, PID: 17317627
-
Abdelmohsen K, Pullmann R Jr, Lal A, Kim HH, Galban S, Yang X, Blethrow JD, Walker M, Shubert J, Gillespie DA, Furneaux H, Gorospe M (2007) Phosphorylation of HuR by Chk2 regulates SIRT1 expression. Mol Cell 25:543–557
-
(2007)
Mol Cell
, vol.25
, pp. 543-557
-
-
Abdelmohsen, K.1
Pullmann, R.2
Lal, A.3
Kim, H.H.4
Galban, S.5
Yang, X.6
Blethrow, J.D.7
Walker, M.8
Shubert, J.9
Gillespie, D.A.10
Furneaux, H.11
Gorospe, M.12
-
2
-
-
55749084738
-
A role for the mitochondrial deacetylase Sirt3 in regulating energy homeostasis
-
COI: 1:CAS:528:DC%2BD1cXht1SgtrbL, PID: 18794531
-
Ahn BH, Kim HS, Song S, Lee IH, Liu J, Vassilopoulos A, Deng CX, Finkel T (2008) A role for the mitochondrial deacetylase Sirt3 in regulating energy homeostasis. Proc Natl Acad Sci USA 105:14447–14452
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 14447-14452
-
-
Ahn, B.H.1
Kim, H.S.2
Song, S.3
Lee, I.H.4
Liu, J.5
Vassilopoulos, A.6
Deng, C.X.7
Finkel, T.8
-
3
-
-
34249669270
-
Sirt1 regulates aging and resistance to oxidative stress in the heart
-
COI: 1:CAS:528:DC%2BD2sXltl2nsbY%3D, PID: 17446436
-
Alcendor RR, Gao S, Zhai P, Zablocki D, Holle E, Yu X, Tian B, Wagner T, Vatner SF, Sadoshima J (2007) Sirt1 regulates aging and resistance to oxidative stress in the heart. Circ Res 100(10):1512–1521
-
(2007)
Circ Res
, vol.100
, Issue.10
, pp. 1512-1521
-
-
Alcendor, R.R.1
Gao, S.2
Zhai, P.3
Zablocki, D.4
Holle, E.5
Yu, X.6
Tian, B.7
Wagner, T.8
Vatner, S.F.9
Sadoshima, J.10
-
4
-
-
84976263041
-
Increased expression of SIRT2 is a novel marker of cellular senescence and is dependent on wild type p53 status
-
COI: 1:CAS:528:DC%2BC28XhtVGmtr3O, PID: 27229617
-
Anwar T, Khosla S, Ramakrishna G (2016) Increased expression of SIRT2 is a novel marker of cellular senescence and is dependent on wild type p53 status. Cell Cycle 15(14):1883–1897
-
(2016)
Cell Cycle
, vol.15
, Issue.14
, pp. 1883-1897
-
-
Anwar, T.1
Khosla, S.2
Ramakrishna, G.3
-
5
-
-
84891275812
-
Metformin modulates hyperglycaemia-induced endothelial senescence and apoptosis through SIRT1
-
COI: 1:CAS:528:DC%2BC3sXhvFOntr3F, PID: 24372553
-
Arunachalam G, Samuel SM, Marei I, Ding H, Triggle CR (2014) Metformin modulates hyperglycaemia-induced endothelial senescence and apoptosis through SIRT1. Br J Pharmacol 171(2):523–535
-
(2014)
Br J Pharmacol
, vol.171
, Issue.2
, pp. 523-535
-
-
Arunachalam, G.1
Samuel, S.M.2
Marei, I.3
Ding, H.4
Triggle, C.R.5
-
6
-
-
84908530414
-
Chemistry: chemical con artists foil drug discovery
-
COI: 1:CAS:528:DC%2BC2cXhs1WjsL7M, PID: 25254460
-
Baell J, Walters MA (2014) Chemistry: chemical con artists foil drug discovery. Nature 513(7519):481–483
-
(2014)
Nature
, vol.513
, Issue.7519
, pp. 481-483
-
-
Baell, J.1
Walters, M.A.2
-
7
-
-
84891947918
-
Loss-of-SIRT1 function during vascular ageing: hyperphosphorylation mediated by cyclin-dependent kinase 5
-
COI: 1:CAS:528:DC%2BC3sXhtlSiurjJ, PID: 23968571
-
Bai B, Vanhoutte PM, Wang Y (2014) Loss-of-SIRT1 function during vascular ageing: hyperphosphorylation mediated by cyclin-dependent kinase 5. Trends Cardiovasc Med 24:81–84
-
(2014)
Trends Cardiovasc Med
, vol.24
, pp. 81-84
-
-
Bai, B.1
Vanhoutte, P.M.2
Wang, Y.3
-
8
-
-
0142212316
-
Oxidant, antioxidant and physical exercise
-
Banerjee AK, Mandal A, Chanda D, Chakraborti S (2013) Oxidant, antioxidant and physical exercise. Mol Cell Biochem 253(1–2):307–312
-
(2013)
Mol Cell Biochem
, vol.253
, Issue.1-2
, pp. 307-312
-
-
Banerjee, A.K.1
Mandal, A.2
Chanda, D.3
Chakraborti, S.4
-
9
-
-
84863453769
-
SIRT7 links H3K18 deacetylation to maintenance of oncogenic transformation
-
COI: 1:CAS:528:DC%2BC38XpvVWjur8%3D, PID: 22722849
-
Barber MF, Michishita-Kioi E, Xi Y, Tasselli L, Kioi M, Moqtaderi Z, Tennen RI, Paredes S, Young NL, Chen K, Struhl K, Garcia BA, Gozani O, Li W, Chua KF (2012) SIRT7 links H3K18 deacetylation to maintenance of oncogenic transformation. Nature 487(7405):114–118
-
(2012)
Nature
, vol.487
, Issue.7405
, pp. 114-118
-
-
Barber, M.F.1
Michishita-Kioi, E.2
Xi, Y.3
Tasselli, L.4
Kioi, M.5
Moqtaderi, Z.6
Tennen, R.I.7
Paredes, S.8
Young, N.L.9
Chen, K.10
Struhl, K.11
Garcia, B.A.12
Gozani, O.13
Li, W.14
Chua, K.F.15
-
10
-
-
33751072349
-
Resveratrol improves health and survival of mice on a high-calorie diet
-
COI: 1:CAS:528:DC%2BD28Xht1Sgtb3I, PID: 17086191
-
Baur JA, Pearson KJ, Price NL, Jamieson HA, Lerin C, Kalra A, Prabhu VV, Allard JS, Lopez-Lluch G, Lewis K, Pistell PJ, Poosala S, Becker KG, Boss O, Gwinn D, Wang M, Ramaswamy S, Fishbein KW, Spencer RG, Lakatta EG, Le Couteur D, Shaw RJ, Navas P, Puigserver P, Ingram DK, de Cabo R, Sinclair DA (2006) Resveratrol improves health and survival of mice on a high-calorie diet. Nature 444:337–342
-
(2006)
Nature
, vol.444
, pp. 337-342
-
-
Baur, J.A.1
Pearson, K.J.2
Price, N.L.3
Jamieson, H.A.4
Lerin, C.5
Kalra, A.6
Prabhu, V.V.7
Allard, J.S.8
Lopez-Lluch, G.9
Lewis, K.10
Pistell, P.J.11
Poosala, S.12
Becker, K.G.13
Boss, O.14
Gwinn, D.15
Wang, M.16
Ramaswamy, S.17
Fishbein, K.W.18
Spencer, R.G.19
Lakatta, E.G.20
Le Couteur, D.21
Shaw, R.J.22
Navas, P.23
Puigserver, P.24
Ingram, D.K.25
de Cabo, R.26
Sinclair, D.A.27
more..
-
11
-
-
81355150447
-
Long-term treadmill exercise induces neuroprotective molecular changes in rat brain
-
COI: 1:CAS:528:DC%2BC3MXhsFCmurfL, PID: 21817108
-
Bayod S, Del Valle J, Canudas AM, Lalanza JF, Sanchez-Roige S, Camins A, Escorihuela RM, Pallàs M (2011) Long-term treadmill exercise induces neuroprotective molecular changes in rat brain. J Appl Physiol 111(5):1380–1390
-
(2011)
J Appl Physiol
, vol.111
, Issue.5
, pp. 1380-1390
-
-
Bayod, S.1
Del Valle, J.2
Canudas, A.M.3
Lalanza, J.F.4
Sanchez-Roige, S.5
Camins, A.6
Escorihuela, R.M.7
Pallàs, M.8
-
12
-
-
84868304039
-
Long-term physical exercise induces changes in sirtuin 1 pathway and oxidative parameters in adult rat tissues
-
COI: 1:CAS:528:DC%2BC38XhtlOnt73M, PID: 22940286
-
Bayod S, del Valle J, Lalanza JF, Sanchez-Roige S, de Luxán-Delgado B, Coto-Montes A, Canudas AM, Camins A, Escorihuela RM, Pallàs M (2012) Long-term physical exercise induces changes in sirtuin 1 pathway and oxidative parameters in adult rat tissues. Exp Gerontol 47:925–935
-
(2012)
Exp Gerontol
, vol.47
, pp. 925-935
-
-
Bayod, S.1
del Valle, J.2
Lalanza, J.F.3
Sanchez-Roige, S.4
de Luxán-Delgado, B.5
Coto-Montes, A.6
Canudas, A.M.7
Camins, A.8
Escorihuela, R.M.9
Pallàs, M.10
-
13
-
-
79959819034
-
SirT3 suppresses hypoxia inducible factor 1alpha and tumor growth by inhibiting mitochondrial ROS production
-
COI: 1:CAS:528:DC%2BC3MXisFent70%3D, PID: 21358671
-
Bell EL, Emerling BM, Ricoult SJ, Guarente L (2011) SirT3 suppresses hypoxia inducible factor 1alpha and tumor growth by inhibiting mitochondrial ROS production. Oncogene 30(26):2986–2996
-
(2011)
Oncogene
, vol.30
, Issue.26
, pp. 2986-2996
-
-
Bell, E.L.1
Emerling, B.M.2
Ricoult, S.J.3
Guarente, L.4
-
14
-
-
19944433088
-
A novel VNTR enhancer within the SIRT3 gene, a human homologue of SIR2, is associated with survival at oldest ages
-
COI: 1:CAS:528:DC%2BD2MXotVKitw%3D%3D, PID: 15676284
-
Bellizzi D, Rose G, Cavalcante P, Covello G, Dato S, De Rango F, Greco V, Maggiolini M, Feraco E, Mari V, Franceschi C, Passarino G, De Benedictis G (2005) A novel VNTR enhancer within the SIRT3 gene, a human homologue of SIR2, is associated with survival at oldest ages. Genomics 85(2):258–263
-
(2005)
Genomics
, vol.85
, Issue.2
, pp. 258-263
-
-
Bellizzi, D.1
Rose, G.2
Cavalcante, P.3
Covello, G.4
Dato, S.5
De Rango, F.6
Greco, V.7
Maggiolini, M.8
Feraco, E.9
Mari, V.10
Franceschi, C.11
Passarino, G.12
De Benedictis, G.13
-
15
-
-
33845208684
-
Characterization of a bidirectional promoter shared between two human genes related to aging: SIRT3 and PSMD13
-
COI: 1:CAS:528:DC%2BD28Xht12jur7K, PID: 17059877
-
Bellizzi D, Dato S, Cavalcante P, Covello G, Di Cianni F, Passarino G, Rose G, De Benedictis G (2007) Characterization of a bidirectional promoter shared between two human genes related to aging: SIRT3 and PSMD13. Genomics 89(1):143–150
-
(2007)
Genomics
, vol.89
, Issue.1
, pp. 143-150
-
-
Bellizzi, D.1
Dato, S.2
Cavalcante, P.3
Covello, G.4
Di Cianni, F.5
Passarino, G.6
Rose, G.7
De Benedictis, G.8
-
16
-
-
84871538934
-
Regulation of chromatin structure by poly(ADP-ribosyl)ation
-
COI: 1:CAS:528:DC%2BC3sXht1ejtLvE, PID: 22969794
-
Beneke S (2012) Regulation of chromatin structure by poly(ADP-ribosyl)ation. Front Genet 3:169
-
(2012)
Front Genet
, vol.3
, pp. 169
-
-
Beneke, S.1
-
17
-
-
46749158332
-
Hormetic modulation of differentiation of normal human epidermal keratinocytes undergoing replicative senescence in vitro
-
COI: 1:CAS:528:DC%2BD1cXosFWhsbo%3D, PID: 18262743
-
Berge U, Kristensen P, Rattan SI (2008) Hormetic modulation of differentiation of normal human epidermal keratinocytes undergoing replicative senescence in vitro. Exp Gerontol 43(7):658–662
-
(2008)
Exp Gerontol
, vol.43
, Issue.7
, pp. 658-662
-
-
Berge, U.1
Kristensen, P.2
Rattan, S.I.3
-
18
-
-
33845571064
-
Deletion of the life span determinant p66Shc prevents age-dependent increases in emotionality and pain sensitivity in mice
-
COI: 1:CAS:528:DC%2BD2sXhsFanuw%3D%3D, PID: 16809014
-
Berry A, Capone F, Giorgio M, Pelicci PG, de Kloet ER, Alleva E, Minghetti L, Cirulli F (2007) Deletion of the life span determinant p66Shc prevents age-dependent increases in emotionality and pain sensitivity in mice. Exp Gerontol 42(1–2):37–45
-
(2007)
Exp Gerontol
, vol.42
, Issue.1-2
, pp. 37-45
-
-
Berry, A.1
Capone, F.2
Giorgio, M.3
Pelicci, P.G.4
de Kloet, E.R.5
Alleva, E.6
Minghetti, L.7
Cirulli, F.8
-
19
-
-
84949974865
-
Hormesis: decoding two sides of the same coin
-
COI: 1:CAS:528:DC%2BC2sXivVensg%3D%3D
-
Bhakta-Guha D, Efferth T (2015) Hormesis: decoding two sides of the same coin. Pharmaceuticals (Basel) 8(4):865–883
-
(2015)
Pharmaceuticals (Basel)
, vol.8
, Issue.4
, pp. 865-883
-
-
Bhakta-Guha, D.1
Efferth, T.2
-
20
-
-
84893820824
-
A comparison of replicative senescence and doxorubicin-induced premature senescence of vascular smooth muscle cells isolated from human aorta
-
COI: 1:CAS:528:DC%2BC2cXhslykur0%3D, PID: 24243065
-
Bielak-Zmijewska A, Wnuk M, Przybylska D, Grabowska W, Lewinska A, Alster O, Korwek Z, Cmoch A, Myszka A, Pikula S, Mosieniak G, Sikora E (2014) A comparison of replicative senescence and doxorubicin-induced premature senescence of vascular smooth muscle cells isolated from human aorta. Biogerontology 15(1):47–64
-
(2014)
Biogerontology
, vol.15
, Issue.1
, pp. 47-64
-
-
Bielak-Zmijewska, A.1
Wnuk, M.2
Przybylska, D.3
Grabowska, W.4
Lewinska, A.5
Alster, O.6
Korwek, Z.7
Cmoch, A.8
Myszka, A.9
Pikula, S.10
Mosieniak, G.11
Sikora, E.12
-
21
-
-
45549098657
-
SirT1 regulates energy metabolism and response to caloric restriction in mice
-
PID: 18335035
-
Boily G, Seifert EL, Bevilacqua L, He XH, Sabourin G, Estey C, Moffat C, Crawford S, Saliba S, Jardine K, Xuan J, Evans M, Harper ME, McBurney MW (2008) SirT1 regulates energy metabolism and response to caloric restriction in mice. PLoS ONE 3(3):e1759
-
(2008)
PLoS ONE
, vol.3
, Issue.3
-
-
Boily, G.1
Seifert, E.L.2
Bevilacqua, L.3
He, X.H.4
Sabourin, G.5
Estey, C.6
Moffat, C.7
Crawford, S.8
Saliba, S.9
Jardine, K.10
Xuan, J.11
Evans, M.12
Harper, M.E.13
McBurney, M.W.14
-
22
-
-
84983440665
-
Slowing ageing by design: the rise of NAD+ and sirtuin-activating compounds
-
Bonkowski MS, Sinclair DA (2016) Slowing ageing by design: the rise of NAD+ and sirtuin-activating compounds. Nat Rev Mol Cell Biol 7(11):679–690
-
(2016)
Nat Rev Mol Cell Biol
, vol.7
, Issue.11
, pp. 679-690
-
-
Bonkowski, M.S.1
Sinclair, D.A.2
-
23
-
-
17144429302
-
Calorie restriction, SIRT1 and metabolism: understanding longevity
-
COI: 1:CAS:528:DC%2BD2MXivVaktLg%3D, PID: 15768047
-
Bordone L, Guarente L (2005) Calorie restriction, SIRT1 and metabolism: understanding longevity. Nat Rev Mol Cell Biol 6(4):298–305
-
(2005)
Nat Rev Mol Cell Biol
, vol.6
, Issue.4
, pp. 298-305
-
-
Bordone, L.1
Guarente, L.2
-
24
-
-
84861183528
-
The effects of aging, physical training, and a single bout of exercise on mitochondrial protein expression in human skeletal muscle
-
COI: 1:CAS:528:DC%2BC38XlvVyht7k%3D, PID: 22449457
-
Bori Z, Zhao Z, Koltai E, Fatouros IG, Jamurtas AZ, Douroudos II, Terzis G, Chatzinikolaou A, Sovatzidis A, Draganidis D, Boldogh I, Radak Z (2012) The effects of aging, physical training, and a single bout of exercise on mitochondrial protein expression in human skeletal muscle. Exp Gerontol 47:417–424
-
(2012)
Exp Gerontol
, vol.47
, pp. 417-424
-
-
Bori, Z.1
Zhao, Z.2
Koltai, E.3
Fatouros, I.G.4
Jamurtas, A.Z.5
Douroudos, I.I.6
Terzis, G.7
Chatzinikolaou, A.8
Sovatzidis, A.9
Draganidis, D.10
Boldogh, I.11
Radak, Z.12
-
25
-
-
80054782483
-
The dual role of sirtuins in cancer
-
PID: 21941620
-
Bosch-Presegué L, Vaquero A (2011) The dual role of sirtuins in cancer. Genes Cancer 2(6):648–662
-
(2011)
Genes Cancer
, vol.2
, Issue.6
, pp. 648-662
-
-
Bosch-Presegué, L.1
Vaquero, A.2
-
26
-
-
79954467406
-
Stabilization of Suv39H1 by SirT1 is part of oxidative stress response and ensures genome protection
-
PID: 21504832
-
Bosch-Presegué L, Raurell-Vila H, Marazuela-Duque A, Kane-Goldsmith N, Valle A, Oliver J, Serrano L, Vaquero A (2011) Stabilization of Suv39H1 by SirT1 is part of oxidative stress response and ensures genome protection. Mol Cell 42(2):210–223
-
(2011)
Mol Cell
, vol.42
, Issue.2
, pp. 210-223
-
-
Bosch-Presegué, L.1
Raurell-Vila, H.2
Marazuela-Duque, A.3
Kane-Goldsmith, N.4
Valle, A.5
Oliver, J.6
Serrano, L.7
Vaquero, A.8
-
27
-
-
15444377466
-
SIRT1 deacetylation and repression of p300 involves lysine residues 1020/1024 within the cell cycle regulatory domain 1
-
COI: 1:CAS:528:DC%2BD2MXit1eku7s%3D, PID: 15632193
-
Bouras T, Fu M, Sauve AA, Wang F, Quong AA, Perkins ND, Hay RT, Gu W, Pestell RG (2005) SIRT1 deacetylation and repression of p300 involves lysine residues 1020/1024 within the cell cycle regulatory domain 1. J Biol Chem 280:10264–10276
-
(2005)
J Biol Chem
, vol.280
, pp. 10264-10276
-
-
Bouras, T.1
Fu, M.2
Sauve, A.A.3
Wang, F.4
Quong, A.A.5
Perkins, N.D.6
Hay, R.T.7
Gu, W.8
Pestell, R.G.9
-
28
-
-
79955591489
-
Age related changes in NAD+ metabolism oxidative stress and Sirt1 activity in wistar rats
-
COI: 1:CAS:528:DC%2BC3MXls1Klu7w%3D, PID: 21541336
-
Braidy N, Guillemin GJ, Mansour H, Chan-Ling T, Poljak A, Grant R (2011) Age related changes in NAD+ metabolism oxidative stress and Sirt1 activity in wistar rats. PLoS ONE 6(4):e19194
-
(2011)
PLoS ONE
, vol.6
, Issue.4
-
-
Braidy, N.1
Guillemin, G.J.2
Mansour, H.3
Chan-Ling, T.4
Poljak, A.5
Grant, R.6
-
29
-
-
84896399265
-
Mapping NAD+ metabolism in the brain of ageing Wistar rats: potential targets for influencing brain senescence
-
COI: 1:CAS:528:DC%2BC2cXjs1Cksro%3D, PID: 24337988
-
Braidy N, Poljak A, Grant R, Jayasena T, Mansour H (2014) Mapping NAD+ metabolism in the brain of ageing Wistar rats: potential targets for influencing brain senescence. Biogerontology 15(2):177–198
-
(2014)
Biogerontology
, vol.15
, Issue.2
, pp. 177-198
-
-
Braidy, N.1
Poljak, A.2
Grant, R.3
Jayasena, T.4
Mansour, H.5
-
30
-
-
0027192267
-
Transcriptional silencing in yeast is associated with reduced nucleosome acetylation
-
COI: 1:CAS:528:DyaK3sXktVansrg%3D, PID: 8458576
-
Braunstein M, Rose AB, Holmes SG, Alis CD, Broach JR (1993) Transcriptional silencing in yeast is associated with reduced nucleosome acetylation. Genes Dev 7:592–604
-
(1993)
Genes Dev
, vol.7
, pp. 592-604
-
-
Braunstein, M.1
Rose, A.B.2
Holmes, S.G.3
Alis, C.D.4
Broach, J.R.5
-
31
-
-
84874238886
-
SIRT3 reverses aging-associated degeneration
-
COI: 1:CAS:528:DC%2BC3sXhvFWjurk%3D, PID: 23375372
-
Brown K, Xie S, Qiu X, Mohrin M, Shin J, Liu Y, Zhang D, Scadden DT, Chen D (2013) SIRT3 reverses aging-associated degeneration. Cell Rep 3(2):319–327
-
(2013)
Cell Rep
, vol.3
, Issue.2
, pp. 319-327
-
-
Brown, K.1
Xie, S.2
Qiu, X.3
Mohrin, M.4
Shin, J.5
Liu, Y.6
Zhang, D.7
Scadden, D.T.8
Chen, D.9
-
32
-
-
84861021850
-
GH and IGF1: roles in energy metabolism of long-living GH mutant mice
-
PID: 22466316
-
Brown-Borg HM, Bartke A (2012) GH and IGF1: roles in energy metabolism of long-living GH mutant mice. J Gerontol A Biol Sci Med Sci 67(6):652–660
-
(2012)
J Gerontol A Biol Sci Med Sci
, vol.67
, Issue.6
, pp. 652-660
-
-
Brown-Borg, H.M.1
Bartke, A.2
-
33
-
-
80053168829
-
Absence of effects of Sir2 overexpression on lifespan in C. elegans and Drosophila
-
COI: 1:CAS:528:DC%2BC3MXht1WltLfK, PID: 21938067
-
Burnett C, Valentini S, Cabreiro F, Goss M, Somogyvári M, Piper MD, Hoddinott M, Sutphin GL, Leko V, McElwee JJ, Vazquez-Manrique RP, Orfila AM, Ackerman D, Au C, Vinti G, Riesen M, Howard K, Neri C, Bedalov A, Kaeberlein M, Soti C, Partridge L, Gems D (2011) Absence of effects of Sir2 overexpression on lifespan in C. elegans and Drosophila. Nature 477(7365):482–485
-
(2011)
Nature
, vol.477
, Issue.7365
, pp. 482-485
-
-
Burnett, C.1
Valentini, S.2
Cabreiro, F.3
Goss, M.4
Somogyvári, M.5
Piper, M.D.6
Hoddinott, M.7
Sutphin, G.L.8
Leko, V.9
McElwee, J.J.10
Vazquez-Manrique, R.P.11
Orfila, A.M.12
Ackerman, D.13
Au, C.14
Vinti, G.15
Riesen, M.16
Howard, K.17
Neri, C.18
Bedalov, A.19
Kaeberlein, M.20
Soti, C.21
Partridge, L.22
Gems, D.23
more..
-
34
-
-
84922006768
-
Hormesis: from mainstream to therapy
-
PID: 25366126
-
Calabrese EJ (2014) Hormesis: from mainstream to therapy. J Cell Commun Signal 8(4):289–291
-
(2014)
J Cell Commun Signal
, vol.8
, Issue.4
, pp. 289-291
-
-
Calabrese, E.J.1
-
35
-
-
67349276169
-
AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity
-
COI: 1:CAS:528:DC%2BD1MXivVKltLc%3D, PID: 19262508
-
Canto C, Gerhart-Hines Z, Feige JN, Lagouge M, Noriega L, Milne JC, Elliott PJ, Puigserver P, Auwerx J (2009) AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity. Nature 458:1056–1060
-
(2009)
Nature
, vol.458
, pp. 1056-1060
-
-
Canto, C.1
Gerhart-Hines, Z.2
Feige, J.N.3
Lagouge, M.4
Noriega, L.5
Milne, J.C.6
Elliott, P.J.7
Puigserver, P.8
Auwerx, J.9
-
36
-
-
84874244599
-
SIRT6 protects human endothelial cells from DNA damage, telomere dysfunction, and senescence
-
COI: 1:CAS:528:DC%2BC3sXis1Cqs7g%3D, PID: 23201774
-
Cardus A, Uryga AK, Walters G, Erusalimsky JD (2013) SIRT6 protects human endothelial cells from DNA damage, telomere dysfunction, and senescence. Cardiovasc Res 97(3):571–579
-
(2013)
Cardiovasc Res
, vol.97
, Issue.3
, pp. 571-579
-
-
Cardus, A.1
Uryga, A.K.2
Walters, G.3
Erusalimsky, J.D.4
-
37
-
-
84881089080
-
Will calorie restriction work in humans?
-
Cava E, Fontana L (2013) Will calorie restriction work in humans? Aging (Albany NY) 5:507–514
-
(2013)
Aging (Albany NY)
, vol.5
, pp. 507-514
-
-
Cava, E.1
Fontana, L.2
-
38
-
-
28844469898
-
Increase in activity during calorie restriction requires Sirt1
-
COI: 1:CAS:528:DC%2BD2MXhtlahsLbJ, PID: 16339438
-
Chen D, Steele AD, Lindquist S, Guarente L (2005) Increase in activity during calorie restriction requires Sirt1. Science 310(5754):1641
-
(2005)
Science
, vol.310
, Issue.5754
, pp. 1641
-
-
Chen, D.1
Steele, A.D.2
Lindquist, S.3
Guarente, L.4
-
39
-
-
85018884737
-
Study of Icariin on raising SIRT6 activity and inhibiting NF-kB inflammation signal pathway of mouse
-
Chen Y, Ping J, Zhang J, Huang JH, Xia SJ, Shen ZY (2012) Study of Icariin on raising SIRT6 activity and inhibiting NF-kB inflammation signal pathway of mouse. Gerontol Health Care 338–341
-
(2012)
Gerontol Health Care
, pp. 338-341
-
-
Chen, Y.1
Ping, J.2
Zhang, J.3
Huang, J.H.4
Xia, S.J.5
Shen, Z.Y.6
-
40
-
-
84883829745
-
Cross-talk between SIRT1 and p66Shc in vascular diseases
-
COI: 1:CAS:528:DC%2BC3sXktlOjtro%3D, PID: 23499302
-
Chen HZ, Wan YZ, Liu DP (2013) Cross-talk between SIRT1 and p66Shc in vascular diseases. Trends Cardiovasc Med 23(7):237–241
-
(2013)
Trends Cardiovasc Med
, vol.23
, Issue.7
, pp. 237-241
-
-
Chen, H.Z.1
Wan, Y.Z.2
Liu, D.P.3
-
41
-
-
0141814680
-
Developmental defects and p53 hyperacetylation in Sir2 homolog (SIRT1)-deficient mice
-
COI: 1:CAS:528:DC%2BD3sXnslyntrc%3D, PID: 12960381
-
Cheng HL, Mostoslavsky R, Saito S, Manis JP, Gu Y, Patel P, Bronson R, Appella E, Alt FW, Chua KF (2003) Developmental defects and p53 hyperacetylation in Sir2 homolog (SIRT1)-deficient mice. Proc Natl Acad Sci USA 100:10794–10799
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 10794-10799
-
-
Cheng, H.L.1
Mostoslavsky, R.2
Saito, S.3
Manis, J.P.4
Gu, Y.5
Patel, P.6
Bronson, R.7
Appella, E.8
Alt, F.W.9
Chua, K.F.10
-
42
-
-
27244435939
-
Mammalian SIRT1 limits replicative life span in response to chronic genotoxic stress
-
COI: 1:CAS:528:DC%2BD2MXntlCrurc%3D, PID: 16054100
-
Chua KF, Mostoslavsky R, Lombard DB, Pang WW, Saito S, Franco S, Kaushal D, Cheng HL, Fischer MR, Stokes N, Murphy MM, Appella E, Alt FW (2005) Mammalian SIRT1 limits replicative life span in response to chronic genotoxic stress. Cell Metab 2:67–76
-
(2005)
Cell Metab
, vol.2
, pp. 67-76
-
-
Chua, K.F.1
Mostoslavsky, R.2
Lombard, D.B.3
Pang, W.W.4
Saito, S.5
Franco, S.6
Kaushal, D.7
Cheng, H.L.8
Fischer, M.R.9
Stokes, N.10
Murphy, M.M.11
Appella, E.12
Alt, F.W.13
-
43
-
-
77956176874
-
Regulation of SIRT1 in cellular functions: role of polyphenols
-
COI: 1:CAS:528:DC%2BC3cXhtV2jurrF, PID: 20450879
-
Chung S, Yao H, Caito S, Hwang JW, Arunachalam G, Rahman I (2010) Regulation of SIRT1 in cellular functions: role of polyphenols. Arch Biochem Biophys 501(1):79–90
-
(2010)
Arch Biochem Biophys
, vol.501
, Issue.1
, pp. 79-90
-
-
Chung, S.1
Yao, H.2
Caito, S.3
Hwang, J.W.4
Arunachalam, G.5
Rahman, I.6
-
44
-
-
84866880582
-
Resveratrol as a calorie restriction mimetic: therapeutic implications
-
COI: 1:CAS:528:DC%2BC38XhsVCjsrbE, PID: 22885100
-
Chung JH, Manganiello V, Dyck JR (2012) Resveratrol as a calorie restriction mimetic: therapeutic implications. Trends Cell Biol 22(10):546–554
-
(2012)
Trends Cell Biol
, vol.22
, Issue.10
, pp. 546-554
-
-
Chung, J.H.1
Manganiello, V.2
Dyck, J.R.3
-
45
-
-
84655167647
-
Association of sirtuin 1 (SIRT1) gene SNPs and transcript expression levels with severe obesity
-
COI: 1:CAS:528:DC%2BC3MXhs1OltrjI
-
Clark SJ, Falchi M, Olsson B, Jacobson P, Cauchi S, Balkau B, Marre M, Lantieri O, Andersson JC, Jernås M, Aitman TJ, Richardson S, Sjöström L, Wong HY, Carlsson LM, Froguel P, Walley AJ (2012) Association of sirtuin 1 (SIRT1) gene SNPs and transcript expression levels with severe obesity. Obesity (Silver Spring) 20(1):178–185
-
(2012)
Obesity (Silver Spring)
, vol.20
, Issue.1
, pp. 178-185
-
-
Clark, S.J.1
Falchi, M.2
Olsson, B.3
Jacobson, P.4
Cauchi, S.5
Balkau, B.6
Marre, M.7
Lantieri, O.8
Andersson, J.C.9
Jernås, M.10
Aitman, T.J.11
Richardson, S.12
Sjöström, L.13
Wong, H.Y.14
Carlsson, L.M.15
Froguel, P.16
Walley, A.J.17
-
46
-
-
84874422422
-
Frailty in elderly people
-
PID: 23395245
-
Clegg A, Young J, Iliffe S, Rikkert MO, Rockwood K (2013) Frailty in elderly people. Lancet 381:752–762
-
(2013)
Lancet
, vol.381
, pp. 752-762
-
-
Clegg, A.1
Young, J.2
Iliffe, S.3
Rikkert, M.O.4
Rockwood, K.5
-
47
-
-
0038050784
-
Fitness effects on the cognitive function of older adults: a meta-analytic study
-
PID: 12661673
-
Colcombe S, Kramer AF (2003) Fitness effects on the cognitive function of older adults: a meta-analytic study. Psychol Sci 14(2):125–130
-
(2003)
Psychol Sci
, vol.14
, Issue.2
, pp. 125-130
-
-
Colcombe, S.1
Kramer, A.F.2
-
48
-
-
67650439330
-
Caloric restriction delays disease onset and mortality in rhesus monkeys
-
COI: 1:CAS:528:DC%2BD1MXos1SrtL0%3D, PID: 19590001
-
Colman RJ, Anderson RM, Johnson SC, Kastman EK, Kosmatka KJ, Beasley TM, Allison DB, Cruzen C, Simmons HA, Kemnitz JW, Weindruch R (2009) Caloric restriction delays disease onset and mortality in rhesus monkeys. Science 325(5937):201–204
-
(2009)
Science
, vol.325
, Issue.5937
, pp. 201-204
-
-
Colman, R.J.1
Anderson, R.M.2
Johnson, S.C.3
Kastman, E.K.4
Kosmatka, K.J.5
Beasley, T.M.6
Allison, D.B.7
Cruzen, C.8
Simmons, H.A.9
Kemnitz, J.W.10
Weindruch, R.11
-
49
-
-
73649133942
-
Skeletal muscle NAMPT is induced by exercise in humans
-
COI: 1:CAS:528:DC%2BC3cXhsFKmtLk%3D, PID: 19887595
-
Costford SR, Bajpeyi S, Pasarica M, Albarado DC, Thomas SC, Xie H, Church TS, Jubrias SA, Conley KE, Smith SR (2010) Skeletal muscle NAMPT is induced by exercise in humans. Am J Physiol Endocrinol Metab 298:E117–E126
-
(2010)
Am J Physiol Endocrinol Metab
, vol.298
, pp. E117-E126
-
-
Costford, S.R.1
Bajpeyi, S.2
Pasarica, M.3
Albarado, D.C.4
Thomas, S.C.5
Xie, H.6
Church, T.S.7
Jubrias, S.A.8
Conley, K.E.9
Smith, S.R.10
-
51
-
-
67650659852
-
Anti-oxidative and anti-inflammatory vasoprotective effects of caloric restriction in aging: role of circulating factors and SIRT1
-
COI: 1:CAS:528:DC%2BD1MXptVShtrY%3D, PID: 19549533
-
Csiszar A, Labinskyy N, Jimenez R, Pinto JT, Ballabh P, Losonczy G, Pearson KJ, de Cabo R, Ungvari Z (2009) Anti-oxidative and anti-inflammatory vasoprotective effects of caloric restriction in aging: role of circulating factors and SIRT1. Mech Ageing Dev 130:518–527
-
(2009)
Mech Ageing Dev
, vol.130
, pp. 518-527
-
-
Csiszar, A.1
Labinskyy, N.2
Jimenez, R.3
Pinto, J.T.4
Ballabh, P.5
Losonczy, G.6
Pearson, K.J.7
de Cabo, R.8
Ungvari, Z.9
-
52
-
-
3042750643
-
Silent information regulator 2 potentiates Foxo1-mediated transcription through its deacetylase activity
-
COI: 1:CAS:528:DC%2BD2cXlvFOhsr0%3D, PID: 15220471
-
Daitoku H, Hatta M, Matsuzaki H, Aratani S, Ohshima T, Miyagishi M, Nakajima T, Fukamizu A (2004) Silent information regulator 2 potentiates Foxo1-mediated transcription through its deacetylase activity. Proc Natl Acad Sci USA 101:10042–10047
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 10042-10047
-
-
Daitoku, H.1
Hatta, M.2
Matsuzaki, H.3
Aratani, S.4
Ohshima, T.5
Miyagishi, M.6
Nakajima, T.7
Fukamizu, A.8
-
53
-
-
83255164138
-
Curcumin induces stress response and hormetically modulates wound healing ability of human skin fibroblasts undergoing ageing in vitro
-
COI: 1:CAS:528:DC%2BC3MXhtlWrt77L, PID: 21380847
-
Demirovic D, Rattan SI (2011) Curcumin induces stress response and hormetically modulates wound healing ability of human skin fibroblasts undergoing ageing in vitro. Biogerontology 12(5):437–444
-
(2011)
Biogerontology
, vol.12
, Issue.5
, pp. 437-444
-
-
Demirovic, D.1
Rattan, S.I.2
-
54
-
-
0037405043
-
Role for human SIRT2 NAD-dependent deacetylase activity in control of mitotic exit in the cell cycle
-
COI: 1:CAS:528:DC%2BD3sXjt1GlsL4%3D, PID: 12697818
-
Dryden SC, Nahhas FA, Nowak JE, Goustin AS, Tainsky MA (2003) Role for human SIRT2 NAD-dependent deacetylase activity in control of mitotic exit in the cell cycle. Mol Cell Biol 23:3173–3185
-
(2003)
Mol Cell Biol
, vol.23
, pp. 3173-3185
-
-
Dryden, S.C.1
Nahhas, F.A.2
Nowak, J.E.3
Goustin, A.S.4
Tainsky, M.A.5
-
55
-
-
81055122671
-
Sirt5 is a NAD-dependent protein lysine demalonylase and desuccinylase
-
COI: 1:CAS:528:DC%2BC3MXhsVagtrnI, PID: 22076378
-
Du J, Zhou Y, Su X, Yu JJ, Khan S, Jiang H, Kim J, Woo J, Kim JH, Choi BH, He B, Chen W, Zhang S, Cerione RA, Auwerx J, Hao Q, Lin H (2011) Sirt5 is a NAD-dependent protein lysine demalonylase and desuccinylase. Science 334:806–809
-
(2011)
Science
, vol.334
, pp. 806-809
-
-
Du, J.1
Zhou, Y.2
Su, X.3
Yu, J.J.4
Khan, S.5
Jiang, H.6
Kim, J.7
Woo, J.8
Kim, J.H.9
Choi, B.H.10
He, B.11
Chen, W.12
Zhang, S.13
Cerione, R.A.14
Auwerx, J.15
Hao, Q.16
Lin, H.17
-
56
-
-
84875431269
-
Flavonoid apigenin is an inhibitor of the NAD+ ase CD38: implications for cellular NAD+ metabolism, protein acetylation, and treatment of metabolic syndrome
-
COI: 1:CAS:528:DC%2BC3sXpvFCktbs%3D, PID: 23172919
-
Escande C, Nin V, Price NL, Capellini V, Gomes AP, Barbosa MT, O’Neil L, White TA, Sinclair DA, Chini EN (2013) Flavonoid apigenin is an inhibitor of the NAD+ ase CD38: implications for cellular NAD+ metabolism, protein acetylation, and treatment of metabolic syndrome. Diabetes 62(4):1084–1093
-
(2013)
Diabetes
, vol.62
, Issue.4
, pp. 1084-1093
-
-
Escande, C.1
Nin, V.2
Price, N.L.3
Capellini, V.4
Gomes, A.P.5
Barbosa, M.T.6
O’Neil, L.7
White, T.A.8
Sinclair, D.A.9
Chini, E.N.10
-
57
-
-
84868649397
-
-
eds), Springer, New York
-
Fahy GM, West MD, Coles LS, Harris SB (eds) (2010) The future of aging: pathways to human life extension. Springer, New York
-
(2010)
The future of aging: pathways to human life extension
-
-
Fahy, G.M.1
West, M.D.2
Coles, L.S.3
Harris, S.B.4
-
58
-
-
77955501963
-
SIRT1 regulates UV-induced DNA repair through deacetylating XPA
-
COI: 1:CAS:528:DC%2BC3cXpsVCnsbo%3D, PID: 20670893
-
Fan W, Luo J (2010) SIRT1 regulates UV-induced DNA repair through deacetylating XPA. Mol Cell 39:247–258
-
(2010)
Mol Cell
, vol.39
, pp. 247-258
-
-
Fan, W.1
Luo, J.2
-
59
-
-
39449118273
-
Exercise training promotes SIRT1 activity in aged rats
-
COI: 1:CAS:528:DC%2BD1cXitVKmtrw%3D, PID: 18069916
-
Ferrara N, Rinaldi B, Corbi G, Conti V, Stiuso P, Boccuti S, Rengo G, Rossi F, Filippelli A (2008) Exercise training promotes SIRT1 activity in aged rats. Rejuvenation Res 11(1):139–150
-
(2008)
Rejuvenation Res
, vol.11
, Issue.1
, pp. 139-150
-
-
Ferrara, N.1
Rinaldi, B.2
Corbi, G.3
Conti, V.4
Stiuso, P.5
Boccuti, S.6
Rengo, G.7
Rossi, F.8
Filippelli, A.9
-
60
-
-
18844402089
-
Functional foods, herbs and nutraceuticals: towards biochemical mechanisms of healthy aging
-
COI: 1:CAS:528:DC%2BD2cXpvVers78%3D, PID: 15547316
-
Ferrari CKB (2004) Functional foods, herbs and nutraceuticals: towards biochemical mechanisms of healthy aging. Biogerontology 5:275–289
-
(2004)
Biogerontology
, vol.5
, pp. 275-289
-
-
Ferrari, C.K.B.1
-
61
-
-
79952501323
-
SIRT3 opposes reprogramming of cancer cell metabolism through HIF1alpha destabilization
-
COI: 1:CAS:528:DC%2BC3MXjtFKis74%3D, PID: 21397863
-
Finley LW, Carracedo A, Lee J, Souza A, Egia A, Zhang J, Teruya-Feldstein J, Moreira PI, Cardoso SM, Clish CB, Pandolfi PP, Haigis MC (2011) SIRT3 opposes reprogramming of cancer cell metabolism through HIF1alpha destabilization. Cancer Cell 19(3):416–428
-
(2011)
Cancer Cell
, vol.19
, Issue.3
, pp. 416-428
-
-
Finley, L.W.1
Carracedo, A.2
Lee, J.3
Souza, A.4
Egia, A.5
Zhang, J.6
Teruya-Feldstein, J.7
Moreira, P.I.8
Cardoso, S.M.9
Clish, C.B.10
Pandolfi, P.P.11
Haigis, M.C.12
-
62
-
-
29744463503
-
Sirtuin 1 (SIRT1) sequence variation is not associated with exceptional human longevity
-
COI: 1:CAS:528:DC%2BD28XhvFygsQ%3D%3D, PID: 16257164
-
Flachsbart F, Croucher PJ, Nikolaus S, Hampe J, Cordes C, Schreiber S, Nebel A (2006) Sirtuin 1 (SIRT1) sequence variation is not associated with exceptional human longevity. Exp Gerontol 41(1):98–102
-
(2006)
Exp Gerontol
, vol.41
, Issue.1
, pp. 98-102
-
-
Flachsbart, F.1
Croucher, P.J.2
Nikolaus, S.3
Hampe, J.4
Cordes, C.5
Schreiber, S.6
Nebel, A.7
-
63
-
-
84872807646
-
Curcumin ameliorates arterial dysfunction and oxidative stress with aging
-
COI: 1:CAS:528:DC%2BC38XhslCnu7rM, PID: 23142245
-
Fleenor BS, Sindler AL, Marvi NK, Howell KL, Zigler ML, Yoshizawa M, Seals DR (2013) Curcumin ameliorates arterial dysfunction and oxidative stress with aging. Exp Gerontol 48:269–276
-
(2013)
Exp Gerontol
, vol.48
, pp. 269-276
-
-
Fleenor, B.S.1
Sindler, A.L.2
Marvi, N.K.3
Howell, K.L.4
Zigler, M.L.5
Yoshizawa, M.6
Seals, D.R.7
-
64
-
-
33744466971
-
Mammalian Sir2 homolog SIRT7 is an activator of RNA polymerase I transcription
-
COI: 1:CAS:528:DC%2BD28XkslCjsb4%3D, PID: 16618798
-
Ford E, Voit R, Liszt G, Magin C, Grummt I, Guarente L (2006) Mammalian Sir2 homolog SIRT7 is an activator of RNA polymerase I transcription. Genes Dev 20:1075–1080
-
(2006)
Genes Dev
, vol.20
, pp. 1075-1080
-
-
Ford, E.1
Voit, R.2
Liszt, G.3
Magin, C.4
Grummt, I.5
Guarente, L.6
-
65
-
-
8144229685
-
Deletion of p66shc gene protects against age-related endothelial dysfunction
-
COI: 1:CAS:528:DC%2BD2cXptVejs70%3D, PID: 15505103
-
Francia P, delli Gatti C, Bachschmid M, Martin-Padura I, Savoia C, Migliaccio E, Pelicci PG, Schiavoni M, Lüscher TF, Volpe M, Cosentino F (2004) Deletion of p66shc gene protects against age-related endothelial dysfunction. Circulation 110(18):2889–2895
-
(2004)
Circulation
, vol.110
, Issue.18
, pp. 2889-2895
-
-
Francia, P.1
delli Gatti, C.2
Bachschmid, M.3
Martin-Padura, I.4
Savoia, C.5
Migliaccio, E.6
Pelicci, P.G.7
Schiavoni, M.8
Lüscher, T.F.9
Volpe, M.10
Cosentino, F.11
-
66
-
-
84978664337
-
Vascular smooth muscle sirtuin-1 protects against diet-induced aortic stiffness
-
COI: 1:CAS:528:DC%2BC28XhtlajurjE, PID: 27432859
-
Fry JL, Al Sayah L, Weisbrod RM, Van Roy I, Weng X, Cohen RA, Bachschmid MM, Seta F (2016) Vascular smooth muscle sirtuin-1 protects against diet-induced aortic stiffness. Hypertension 68(3):775–784
-
(2016)
Hypertension
, vol.68
, Issue.3
, pp. 775-784
-
-
Fry, J.L.1
Al Sayah, L.2
Weisbrod, R.M.3
Van Roy, I.4
Weng, X.5
Cohen, R.A.6
Bachschmid, M.M.7
Seta, F.8
-
67
-
-
34250758020
-
2 accelerates cellular senescence by accumulation of acetylated p53 via decrease in the function of SIRT1 by NAD+ depletion
-
COI: 1:CAS:528:DC%2BD2sXms1yrs7g%3D, PID: 17595514
-
2 accelerates cellular senescence by accumulation of acetylated p53 via decrease in the function of SIRT1 by NAD+ depletion. Cell Physiol Biochem 20:45–54
-
(2007)
Cell Physiol Biochem
, vol.20
, pp. 45-54
-
-
Furukawa, A.1
Tada-Oikawa, S.2
Kawanishi, S.3
Oikawa, S.4
-
68
-
-
84890569395
-
SIRT6, a protein with many faces
-
COI: 1:CAS:528:DC%2BC3sXhvVyqtrrJ, PID: 24213807
-
Gertler AA, Cohen HY (2013) SIRT6, a protein with many faces. Biogerontology 14:629–639
-
(2013)
Biogerontology
, vol.14
, pp. 629-639
-
-
Gertler, A.A.1
Cohen, H.Y.2
-
69
-
-
84922245935
-
Curcumin induces senescence of primary human cells building the vasculature in a DNA damage and ATM-independent manner
-
Grabowska W, Kucharewicz K, Wnuk M, Lewinska A, Suszek M, Przybylska D, Mosieniak G, Sikora E, Bielak-Zmijewska A (2015) Curcumin induces senescence of primary human cells building the vasculature in a DNA damage and ATM-independent manner. Age (Dordr) 37(1):9744
-
(2015)
Age (Dordr)
, vol.37
, Issue.1
, pp. 9744
-
-
Grabowska, W.1
Kucharewicz, K.2
Wnuk, M.3
Lewinska, A.4
Suszek, M.5
Przybylska, D.6
Mosieniak, G.7
Sikora, E.8
Bielak-Zmijewska, A.9
-
70
-
-
84964777750
-
Curcumin elevates sirtuin level but does not postpone in vitro senescence of human cells building the vasculature
-
PID: 27034011
-
Grabowska W, Suszek M, Wnuk M, Lewinska A, Wasiak E, Sikora E, Bielak-Zmijewska A (2016) Curcumin elevates sirtuin level but does not postpone in vitro senescence of human cells building the vasculature. Oncotarget 7(15):19201–19213
-
(2016)
Oncotarget
, vol.7
, Issue.15
, pp. 19201-19213
-
-
Grabowska, W.1
Suszek, M.2
Wnuk, M.3
Lewinska, A.4
Wasiak, E.5
Sikora, E.6
Bielak-Zmijewska, A.7
-
71
-
-
84877994005
-
A dietary regimen of caloric restriction or pharmacological activation of SIRT1 to delay the onset of neurodegeneration
-
COI: 1:CAS:528:DC%2BC3sXoslyktbw%3D, PID: 23699506
-
Graff J, Kahn M, Samiei A, Gao J, Ota KT, Rei D, Tsai LH (2013) A dietary regimen of caloric restriction or pharmacological activation of SIRT1 to delay the onset of neurodegeneration. J Neurosci 33:8951–8960
-
(2013)
J Neurosci
, vol.33
, pp. 8951-8960
-
-
Graff, J.1
Kahn, M.2
Samiei, A.3
Gao, J.4
Ota, K.T.5
Rei, D.6
Tsai, L.H.7
-
72
-
-
26244446951
-
Effects of increased dietary fat and exercise on skeletal muscle lipid peroxidation and antioxidant capacity in male rats
-
COI: 1:CAS:528:DC%2BD2MXht1eksL3I, PID: 15633018
-
Greathouse KL, Samuels M, DiMarco NM, Criswell DS (2005) Effects of increased dietary fat and exercise on skeletal muscle lipid peroxidation and antioxidant capacity in male rats. Eur J Nutr 44(7):429–435
-
(2005)
Eur J Nutr
, vol.44
, Issue.7
, pp. 429-435
-
-
Greathouse, K.L.1
Samuels, M.2
DiMarco, N.M.3
Criswell, D.S.4
-
73
-
-
64849107827
-
Involvement of SIRT7 in resumption of rDNA transcription at the exit from mitosis
-
COI: 1:CAS:528:DC%2BD1MXjs1Wls7Y%3D, PID: 19174463
-
Grob A, Roussel P, Wright JE, McStay B, Hernandez-Verdun D, Sirri V (2009) Involvement of SIRT7 in resumption of rDNA transcription at the exit from mitosis. J Cell Sci 122(Pt 4):489–498
-
(2009)
J Cell Sci
, vol.122
, pp. 489-498
-
-
Grob, A.1
Roussel, P.2
Wright, J.E.3
McStay, B.4
Hernandez-Verdun, D.5
Sirri, V.6
-
74
-
-
84958719541
-
Curcumin activates autophagy and attenuates oxidative damage in EA.hy926 cells via the Akt/mTOR pathway
-
COI: 1:CAS:528:DC%2BC28XmsFGlsr4%3D, PID: 26781771
-
Guo S, Long M, Li X, Zhu S, Zhang M, Yang Z (2016) Curcumin activates autophagy and attenuates oxidative damage in EA.hy926 cells via the Akt/mTOR pathway. Mol Med Rep 13(3):2187–2193
-
(2016)
Mol Med Rep
, vol.13
, Issue.3
, pp. 2187-2193
-
-
Guo, S.1
Long, M.2
Li, X.3
Zhu, S.4
Zhang, M.5
Yang, Z.6
-
75
-
-
33748316536
-
SIRT4 inhibits glutamate dehydrogenase and opposes the effects of calorie restriction in pancreatic beta cells
-
COI: 1:CAS:528:DC%2BD28XpvVKiur8%3D, PID: 16959573
-
Haigis MC, Mostoslavsky R, Haigis KM, Fahie K, Christodoulou DC, Murphy AJ, Valenzuela DM, Yancopoulos GD, Karow M, Blander G, Wolberger C, Prolla TA, Weindruch R, Alt FW, Guarente L (2006) SIRT4 inhibits glutamate dehydrogenase and opposes the effects of calorie restriction in pancreatic beta cells. Cell 126:941–954
-
(2006)
Cell
, vol.126
, pp. 941-954
-
-
Haigis, M.C.1
Mostoslavsky, R.2
Haigis, K.M.3
Fahie, K.4
Christodoulou, D.C.5
Murphy, A.J.6
Valenzuela, D.M.7
Yancopoulos, G.D.8
Karow, M.9
Blander, G.10
Wolberger, C.11
Prolla, T.A.12
Weindruch, R.13
Alt, F.W.14
Guarente, L.15
-
76
-
-
84861161546
-
SIRT3 is a mitochondrial tumor suppressor: a scientific tale that connects aberrant cellular ROS, the Warburg effect, and carcinogenesis
-
COI: 1:CAS:528:DC%2BC38XmvF2ntL8%3D, PID: 22589271
-
Haigis MC, Deng CX, Finley LWS, Kim HS, Gius D (2012) SIRT3 is a mitochondrial tumor suppressor: a scientific tale that connects aberrant cellular ROS, the Warburg effect, and carcinogenesis. Cancer Res 72(10):2468–2472
-
(2012)
Cancer Res
, vol.72
, Issue.10
, pp. 2468-2472
-
-
Haigis, M.C.1
Deng, C.X.2
Finley, L.W.S.3
Kim, H.S.4
Gius, D.5
-
77
-
-
84874594425
-
The sirtuin family’s role in aging and age-associated pathologies
-
COI: 1:CAS:528:DC%2BC3sXjvVyhsLo%3D, PID: 23454760
-
Hall JA, Dominy JE, Lee Y, Puigserver P (2013) The sirtuin family’s role in aging and age-associated pathologies. J Clin Invest 123:973–979
-
(2013)
J Clin Invest
, vol.123
, pp. 973-979
-
-
Hall, J.A.1
Dominy, J.E.2
Lee, Y.3
Puigserver, P.4
-
78
-
-
39749087530
-
SIRT1 regulates apoptosis and Nanog expression in mouse embryonic stem cells by controlling p53 subcellular localization
-
COI: 1:CAS:528:DC%2BD1cXjslegtr0%3D, PID: 18371449
-
Han MK, Song EK, Guo Y, Ou X, Mantel C, Broxmeyer HE (2008) SIRT1 regulates apoptosis and Nanog expression in mouse embryonic stem cells by controlling p53 subcellular localization. Cell Stem Cell 2:241–251
-
(2008)
Cell Stem Cell
, vol.2
, pp. 241-251
-
-
Han, M.K.1
Song, E.K.2
Guo, Y.3
Ou, X.4
Mantel, C.5
Broxmeyer, H.E.6
-
79
-
-
34548700597
-
Rapamycin: something old, something new, sometimes borrowed and now renewed
-
COI: 1:CAS:528:DC%2BD2sXhtFGqu7fE, PID: 17728765
-
Hartford CM, Ratain MJ (2007) Rapamycin: something old, something new, sometimes borrowed and now renewed. Clin Pharmacol Ther 82(4):381–388
-
(2007)
Clin Pharmacol Ther
, vol.82
, Issue.4
, pp. 381-388
-
-
Hartford, C.M.1
Ratain, M.J.2
-
80
-
-
0031849916
-
Evidence for 50 AMP-activated protein kinase mediation of the effect of muscle contraction on glucose transport
-
COI: 1:CAS:528:DyaK1cXltFyrtb4%3D, PID: 9703344
-
Hayashi T, Hirshman MF, Kurth EJ, Winder WW, Goodyear LJ (1998) Evidence for 50 AMP-activated protein kinase mediation of the effect of muscle contraction on glucose transport. Diabetes 47:1369–1373
-
(1998)
Diabetes
, vol.47
, pp. 1369-1373
-
-
Hayashi, T.1
Hirshman, M.F.2
Kurth, E.J.3
Winder, W.W.4
Goodyear, L.J.5
-
81
-
-
84925377623
-
Protective effects of curcumin on acute gentamicin-induced nephrotoxicity in rats
-
COI: 1:CAS:528:DC%2BC2MXksF2ltr0%3D, PID: 25730179
-
He L, Peng X, Zhu J, Liu G, Chen X, Tang C, Liu H, Liu F, Peng Y (2015) Protective effects of curcumin on acute gentamicin-induced nephrotoxicity in rats. Can J Physiol Pharmacol 93(4):275–282
-
(2015)
Can J Physiol Pharmacol
, vol.93
, Issue.4
, pp. 275-282
-
-
He, L.1
Peng, X.2
Zhu, J.3
Liu, G.4
Chen, X.5
Tang, C.6
Liu, H.7
Liu, F.8
Peng, Y.9
-
82
-
-
78650758398
-
Sirt1 improves healthy ageing and protects from metabolic syndrome-associated cancer
-
Herranz D, Munoz-Martin M, Canamero M, Mulero F, Martinez-Pastor B, Fernandez-Capetillo O, Serrano M (2010) Sirt1 improves healthy ageing and protects from metabolic syndrome-associated cancer. Nat Commun 1:1–8
-
(2010)
Nat Commun
, vol.1
, pp. 1-8
-
-
Herranz, D.1
Munoz-Martin, M.2
Canamero, M.3
Mulero, F.4
Martinez-Pastor, B.5
Fernandez-Capetillo, O.6
Serrano, M.7
-
83
-
-
77950806433
-
SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation
-
COI: 1:CAS:528:DC%2BC3cXislahsLY%3D, PID: 20203611
-
Hirschey MD, Shimazu T, Goetzman E, Jing E, Schwer B, Lombard DB, Grueter CA, Harris C, Biddinger S, Ilkayeva OR, Stevens RD, Li Y, Saha AK, Ruderman NB, Bain JR, Newgard CB, Farese RV Jr, Alt FW, Kahn CR, Verdin E (2010) SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation. Nature 464(7285):121–125
-
(2010)
Nature
, vol.464
, Issue.7285
, pp. 121-125
-
-
Hirschey, M.D.1
Shimazu, T.2
Goetzman, E.3
Jing, E.4
Schwer, B.5
Lombard, D.B.6
Grueter, C.A.7
Harris, C.8
Biddinger, S.9
Ilkayeva, O.R.10
Stevens, R.D.11
Li, Y.12
Saha, A.K.13
Ruderman, N.B.14
Bain, J.R.15
Newgard, C.B.16
Farese, R.V.17
Alt, F.W.18
Kahn, C.R.19
Verdin, E.20
more..
-
84
-
-
84891503453
-
SIRT4 regulates ATP homeostasis and mediates a retrograde signaling via AMPK
-
COI: 1:CAS:528:DC%2BC2cXntVWru7Y%3D
-
Ho L, Titus AS, Banerjee KK, George S, Lin W, Deota S, Saha AK, Nakamura K, Gut P, Verdin E, Kolthur-Seetharam U (2013) SIRT4 regulates ATP homeostasis and mediates a retrograde signaling via AMPK. Aging (Albany NY) 5(11):835–849
-
(2013)
Aging (Albany NY)
, vol.5
, Issue.11
, pp. 835-849
-
-
Ho, L.1
Titus, A.S.2
Banerjee, K.K.3
George, S.4
Lin, W.5
Deota, S.6
Saha, A.K.7
Nakamura, K.8
Gut, P.9
Verdin, E.10
Kolthur-Seetharam, U.11
-
85
-
-
84858797950
-
Sirtuins as regulators of metabolism and healthspan
-
COI: 1:CAS:528:DC%2BC38XjtlOktbw%3D, PID: 22395773
-
Houtkooper RH, Pirinen E, Auwerx J (2012) Sirtuins as regulators of metabolism and healthspan. Nat Rev Mol Cell Biol 13:225–238
-
(2012)
Nat Rev Mol Cell Biol
, vol.13
, pp. 225-238
-
-
Houtkooper, R.H.1
Pirinen, E.2
Auwerx, J.3
-
86
-
-
0141719702
-
Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan
-
COI: 1:CAS:528:DC%2BD3sXntFCitr4%3D, PID: 12939617
-
Howitz KT, Bitterman KJ, Cohen HY, Lamming DW, Lavu S, Wood JG, Zipkin RE, Chung P, Kisielewski A, Zhang LL, Scherer B, Sinclair DA (2003) Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan. Nature 425:191–196
-
(2003)
Nature
, vol.425
, pp. 191-196
-
-
Howitz, K.T.1
Bitterman, K.J.2
Cohen, H.Y.3
Lamming, D.W.4
Lavu, S.5
Wood, J.G.6
Zipkin, R.E.7
Chung, P.8
Kisielewski, A.9
Zhang, L.L.10
Scherer, B.11
Sinclair, D.A.12
-
87
-
-
78650172708
-
Silent information regulator 1 protects the heart from ischemia/reperfusion
-
PID: 21060073
-
Hsu CP, Zhai P, Yamamoto T, Maejima Y, Matsushima S, Hariharan N, Shao D, Takagi H, Oka S, Sadoshima J (2010) Silent information regulator 1 protects the heart from ischemia/reperfusion. Circulation 122:2170–2182
-
(2010)
Circulation
, vol.122
, pp. 2170-2182
-
-
Hsu, C.P.1
Zhai, P.2
Yamamoto, T.3
Maejima, Y.4
Matsushima, S.5
Hariharan, N.6
Shao, D.7
Takagi, H.8
Oka, S.9
Sadoshima, J.10
-
88
-
-
45849137875
-
SIRT1 overexpression antagonizes cellular senescence with activated ERK/S6k1 signaling in human diploid fibroblasts
-
PID: 18320031
-
Huang J, Gan Q, Han L, Li J, Zhang H, Sun Y, Zhang Z, Tong T (2008) SIRT1 overexpression antagonizes cellular senescence with activated ERK/S6k1 signaling in human diploid fibroblasts. PLoS ONE 3(3):e1710
-
(2008)
PLoS ONE
, vol.3
, Issue.3
-
-
Huang, J.1
Gan, Q.2
Han, L.3
Li, J.4
Zhang, H.5
Sun, Y.6
Zhang, Z.7
Tong, T.8
-
89
-
-
84961291322
-
Effect of curcumin supplementation on physiological fatigue and physical performance in mice
-
COI: 1:CAS:528:DC%2BC2MXktl2nu7c%3D, PID: 25647661
-
Huang WC, Chiu WC, Chuang HL, Tang DW, Lee ZM, Wei L, Chen FA, Huang CC (2015) Effect of curcumin supplementation on physiological fatigue and physical performance in mice. Nutrients 7(2):905–921
-
(2015)
Nutrients
, vol.7
, Issue.2
, pp. 905-921
-
-
Huang, W.C.1
Chiu, W.C.2
Chuang, H.L.3
Tang, D.W.4
Lee, Z.M.5
Wei, L.6
Chen, F.A.7
Huang, C.C.8
-
90
-
-
84962044930
-
W effect of exercise training on skeletal muscle SIRT1 and PGC-1α expression levels in rats of different age
-
PID: 27076782
-
Huang C, Wang T, Tung Y, Lin WT (2016) W effect of exercise training on skeletal muscle SIRT1 and PGC-1α expression levels in rats of different age. Int J Med Sci 13(4):260–270
-
(2016)
Int J Med Sci
, vol.13
, Issue.4
, pp. 260-270
-
-
Huang, C.1
Wang, T.2
Tung, Y.3
Lin, W.T.4
-
91
-
-
84896739647
-
Small molecule SIRT1 activators for the treatment of aging and age-related diseases
-
COI: 1:CAS:528:DC%2BC2cXjsVWgurg%3D, PID: 24439680
-
Hubbard BP, Sinclair DA (2014) Small molecule SIRT1 activators for the treatment of aging and age-related diseases. Trends Pharmacol Sci 35(3):146–154
-
(2014)
Trends Pharmacol Sci
, vol.35
, Issue.3
, pp. 146-154
-
-
Hubbard, B.P.1
Sinclair, D.A.2
-
92
-
-
84877064267
-
Redox regulation of SIRT1 inflammation and cellular senescence
-
COI: 1:CAS:528:DC%2BC3sXptVyltLY%3D, PID: 23542362
-
Hwang J, Yao H, Caito S, Sundar IK, Rahman I (2013) Redox regulation of SIRT1 inflammation and cellular senescence. Free Radic Biol Med 61:95–110
-
(2013)
Free Radic Biol Med
, vol.61
, pp. 95-110
-
-
Hwang, J.1
Yao, H.2
Caito, S.3
Sundar, I.K.4
Rahman, I.5
-
93
-
-
84904751060
-
NAD+ and sirtuins in aging and disease
-
COI: 1:CAS:528:DC%2BC2cXnsVeqsr4%3D, PID: 24786309
-
Imai S, Guarente L (2014) NAD+ and sirtuins in aging and disease. Trends Cell Biol 24(8):464–471
-
(2014)
Trends Cell Biol
, vol.24
, Issue.8
, pp. 464-471
-
-
Imai, S.1
Guarente, L.2
-
94
-
-
84923349090
-
Calorie restriction mimetics: can you have your cake and eat it, too?
-
Ingram DK, Roth GS (2015) Calorie restriction mimetics: can you have your cake and eat it, too? Ageing Res Rev 20C:46–62
-
(2015)
Ageing Res Rev
, vol.20C
, pp. 46-62
-
-
Ingram, D.K.1
Roth, G.S.2
-
95
-
-
33646948539
-
Calorie restriction mimetics: an emerging research field
-
COI: 1:CAS:528:DC%2BD28XktVOiu7k%3D, PID: 16626389
-
Ingram DK, Zhu M, Mamczarz J, Zou S, Lane MA, Roth GS, deCabo R (2006) Calorie restriction mimetics: an emerging research field. Aging Cell 5(2):97–108
-
(2006)
Aging Cell
, vol.5
, Issue.2
, pp. 97-108
-
-
Ingram, D.K.1
Zhu, M.2
Mamczarz, J.3
Zou, S.4
Lane, M.A.5
Roth, G.S.6
deCabo, R.7
-
96
-
-
84901622078
-
Paeonol protects against premature senescence in endothelial cells by modulating Sirtuin 1 pathway
-
COI: 1:CAS:528:DC%2BC2cXnslelsrc%3D, PID: 24768807
-
Jamal J, Mustafa MR, Wong PF (2014) Paeonol protects against premature senescence in endothelial cells by modulating Sirtuin 1 pathway. J Ethnopharmacol 154:428–436
-
(2014)
J Ethnopharmacol
, vol.154
, pp. 428-436
-
-
Jamal, J.1
Mustafa, M.R.2
Wong, P.F.3
-
97
-
-
84882779240
-
The role of polyphenols in the modulation of sirtuins and other pathways involved in Alzheimer’s disease
-
COI: 1:CAS:528:DC%2BC3sXhvV2gtLvJ, PID: 23831960
-
Jayasena T, Poljak A, Smythe G, Braidy N, Münch G, Sachdev P (2013) The role of polyphenols in the modulation of sirtuins and other pathways involved in Alzheimer’s disease. Ageing Res Rev 12(4):867–883
-
(2013)
Ageing Res Rev
, vol.12
, Issue.4
, pp. 867-883
-
-
Jayasena, T.1
Poljak, A.2
Smythe, G.3
Braidy, N.4
Münch, G.5
Sachdev, P.6
-
98
-
-
84876359638
-
SIRT4 has tumor suppressive activity and regulates the cellular metabolic response to DNA damage by inhibiting mitochondrial glutamine metabolism
-
COI: 1:CAS:528:DC%2BC3sXlsFegu7c%3D, PID: 23562301
-
Jeong MS, Xiao C, Finley LWS, Lahusen T, Souza AL, Pierce K, Li YH, Wang X, Laurent G, German NJ, Xu X, Li C, Wang RH, Lee J, Csibi A, Cerione R, Blenis J, Clish CB, Kimmelman A, Deng CX, Haigis MC (2013) SIRT4 has tumor suppressive activity and regulates the cellular metabolic response to DNA damage by inhibiting mitochondrial glutamine metabolism. Cancer Cell 23(4):450–463
-
(2013)
Cancer Cell
, vol.23
, Issue.4
, pp. 450-463
-
-
Jeong, M.S.1
Xiao, C.2
Finley, L.W.S.3
Lahusen, T.4
Souza, A.L.5
Pierce, K.6
Li, Y.H.7
Wang, X.8
Laurent, G.9
German, N.J.10
Xu, X.11
Li, C.12
Wang, R.H.13
Lee, J.14
Csibi, A.15
Cerione, R.16
Blenis, J.17
Clish, C.B.18
Kimmelman, A.19
Deng, C.X.20
Haigis, M.C.21
more..
-
99
-
-
84994048785
-
SIRT1-mediated deacetylation of PGC1a attributes to the protection of curcumin against glutamate excitotoxicity in cortical neurons
-
COI: 1:CAS:528:DC%2BC28XhsVehurvI, PID: 27568287
-
Jia N, Sun Q, Su Q, Chen G (2016) SIRT1-mediated deacetylation of PGC1a attributes to the protection of curcumin against glutamate excitotoxicity in cortical neurons. Biochem Biophys Res Commun 478(3):1376–1381
-
(2016)
Biochem Biophys Res Commun
, vol.478
, Issue.3
, pp. 1376-1381
-
-
Jia, N.1
Sun, Q.2
Su, Q.3
Chen, G.4
-
100
-
-
84875881601
-
SIRT6 regulates TNF-alpha secretion through hydrolysis of long-chain fatty acyl lysine
-
COI: 1:CAS:528:DC%2BC3sXlt1arsbk%3D, PID: 23552949
-
Jiang H, Khan S, Wang Y, Charron G, He B, Sebastian C, Du J, Kim R, Ge E, Mostoslavsky R, Hang HC, Hao Q, Lin H (2013) SIRT6 regulates TNF-alpha secretion through hydrolysis of long-chain fatty acyl lysine. Nature 496:110–113
-
(2013)
Nature
, vol.496
, pp. 110-113
-
-
Jiang, H.1
Khan, S.2
Wang, Y.3
Charron, G.4
He, B.5
Sebastian, C.6
Du, J.7
Kim, R.8
Ge, E.9
Mostoslavsky, R.10
Hang, H.C.11
Hao, Q.12
Lin, H.13
-
101
-
-
84992478160
-
Curcumin inhibited HGF-induced EMT and angiogenesis through regulating c-Met dependent PI3K/Akt/mTOR signaling pathways in lung cancer
-
COI: 1:CAS:528:DC%2BC28XhtlCisLzN, PID: 27525306
-
Jiao D, Wang J, Lu W, Tang X, Chen J, Mou H, Chen QY (2016) Curcumin inhibited HGF-induced EMT and angiogenesis through regulating c-Met dependent PI3K/Akt/mTOR signaling pathways in lung cancer. Mol Ther Oncolytics 3:16018
-
(2016)
Mol Ther Oncolytics
, vol.3
, pp. 16018
-
-
Jiao, D.1
Wang, J.2
Lu, W.3
Tang, X.4
Chen, J.5
Mou, H.6
Chen, Q.Y.7
-
102
-
-
80052291180
-
Sirtuin-3 (Sirt3) regulates skeletal muscle metabolism and insulin signaling via altered mitochondrial oxidation and reactive oxygen species production
-
COI: 1:CAS:528:DC%2BC3MXhtFCltbfJ, PID: 21873205
-
Jing E, Emanuelli B, Hirschey MD, Boucher J, Lee KY, Lombard D, Verdin EM, Kahn CR (2011) Sirtuin-3 (Sirt3) regulates skeletal muscle metabolism and insulin signaling via altered mitochondrial oxidation and reactive oxygen species production. Proc Natl Acad Sci USA 108(35):14608–14613
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, Issue.35
, pp. 14608-14613
-
-
Jing, E.1
Emanuelli, B.2
Hirschey, M.D.3
Boucher, J.4
Lee, K.Y.5
Lombard, D.6
Verdin, E.M.7
Kahn, C.R.8
-
103
-
-
84872527628
-
mTOR is a key modulator of ageing and age-related disease
-
COI: 1:CAS:528:DC%2BC3sXptlyntg%3D%3D, PID: 23325216
-
Johnson SC, Rabinovitch PS, Kaeberlein M (2013) mTOR is a key modulator of ageing and age-related disease. Nature 493:338–345
-
(2013)
Nature
, vol.493
, pp. 338-345
-
-
Johnson, S.C.1
Rabinovitch, P.S.2
Kaeberlein, M.3
-
104
-
-
0033214237
-
The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms
-
COI: 1:CAS:528:DyaK1MXmvFOitbc%3D, PID: 10521401
-
Kaeberlein M, McVey M, Guarente L (1999) The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms. Genes Dev 13:2570–2580
-
(1999)
Genes Dev
, vol.13
, pp. 2570-2580
-
-
Kaeberlein, M.1
McVey, M.2
Guarente, L.3
-
105
-
-
19344374925
-
Sir2-independent life span extension by calorie restriction in yeast
-
PID: 15328540
-
Kaeberlein M, Kirkland KT, Fields S, Kennedy BK (2004) Sir2-independent life span extension by calorie restriction in yeast. PLoS Biol 2(9):E296
-
(2004)
PLoS Biol
, vol.2
, Issue.9
, pp. E296
-
-
Kaeberlein, M.1
Kirkland, K.T.2
Fields, S.3
Kennedy, B.K.4
-
106
-
-
77956550868
-
Human SIRT6 promotes DNA end resection through CtIP deacetylation
-
COI: 1:CAS:528:DC%2BC3cXhtFajs7rF, PID: 20829486
-
Kaidi A, Weinert BT, Choudhary C, Jackson SP (2010) Human SIRT6 promotes DNA end resection through CtIP deacetylation. Science 329(5997):1348–1353
-
(2010)
Science
, vol.329
, Issue.5997
, pp. 1348-1353
-
-
Kaidi, A.1
Weinert, B.T.2
Choudhary, C.3
Jackson, S.P.4
-
107
-
-
39649100868
-
Regulation of SIRT6 protein levels by nutrient availability
-
COI: 1:CAS:528:DC%2BD1cXisVSqs7c%3D, PID: 18242175
-
Kanfi Y, Shalman R, Peshti V, Pilosof SN, Gozlan YM, Pearson KJ, Lerrer B, Moazed D, Marine JC, de Cabo R, Cohen HY (2008) Regulation of SIRT6 protein levels by nutrient availability. FEBS Lett 582(5):543–548
-
(2008)
FEBS Lett
, vol.582
, Issue.5
, pp. 543-548
-
-
Kanfi, Y.1
Shalman, R.2
Peshti, V.3
Pilosof, S.N.4
Gozlan, Y.M.5
Pearson, K.J.6
Lerrer, B.7
Moazed, D.8
Marine, J.C.9
de Cabo, R.10
Cohen, H.Y.11
-
108
-
-
84858000209
-
The sirtuin SIRT6 regulates lifespan in male mice
-
COI: 1:CAS:528:DC%2BC38XislyntbY%3D, PID: 22367546
-
Kanfi Y, Naiman S, Amir G, Peshti V, Zinman G, Nahum L, Bar-Joseph Z, Cohen HY (2012) The sirtuin SIRT6 regulates lifespan in male mice. Nature 483:218–221
-
(2012)
Nature
, vol.483
, pp. 218-221
-
-
Kanfi, Y.1
Naiman, S.2
Amir, G.3
Peshti, V.4
Zinman, G.5
Nahum, L.6
Bar-Joseph, Z.7
Cohen, H.Y.8
-
109
-
-
77958559652
-
2-induced oxidative stress and senescence via SirT1 activation
-
COI: 1:CAS:528:DC%2BC3MXhvVeku7s%3D, PID: 20644332
-
2-induced oxidative stress and senescence via SirT1 activation. J Atheroscler Thromb 17:970–979
-
(2010)
J Atheroscler Thromb
, vol.17
, pp. 970-979
-
-
Kao, C.L.1
Chen, L.K.2
Chang, Y.L.3
Yung, M.C.4
Hsu, C.C.5
Chen, Y.C.6
Lo, W.L.7
Chen, S.J.8
Ku, H.H.9
Hwang, S.J.10
-
110
-
-
84880160092
-
Antagonistic crosstalk between NF-kappaB and SIRT1 in the regulation of inflammation and metabolic disorders
-
COI: 1:CAS:528:DC%2BC3sXhtFWjt7nN, PID: 23770291
-
Kauppinen A, Suuronen T, Ojala J, Kaarniranta K, Salminen A (2013) Antagonistic crosstalk between NF-kappaB and SIRT1 in the regulation of inflammation and metabolic disorders. Cell Signal 25:1939–1948
-
(2013)
Cell Signal
, vol.25
, pp. 1939-1948
-
-
Kauppinen, A.1
Suuronen, T.2
Ojala, J.3
Kaarniranta, K.4
Salminen, A.5
-
111
-
-
0027771804
-
A C. elegans mutant that lives twice as long as wild type
-
COI: 1:STN:280:DyaK2c%2FmslensQ%3D%3D, PID: 8247153
-
Kenyon C, Chang J, Gensch E, Rudner A, Tabtiang R (1993) A C. elegans mutant that lives twice as long as wild type. Nature 366:461–464
-
(1993)
Nature
, vol.366
, pp. 461-464
-
-
Kenyon, C.1
Chang, J.2
Gensch, E.3
Rudner, A.4
Tabtiang, R.5
-
112
-
-
84874487252
-
Sirtuin 7 oncogenic potential in human hepatocellular carcinoma and its regulation by the tumor suppressors MiR-125a-5p and MiR-125b
-
COI: 1:CAS:528:DC%2BC3sXjsFeltbs%3D, PID: 23079745
-
Kim JK, Noh JH, Jung KH, Eun JW, Bae HJ, Kim MG, Chang YG, Shen Q, Park WS, Lee JY, Borlak J, Nam SW (2013) Sirtuin 7 oncogenic potential in human hepatocellular carcinoma and its regulation by the tumor suppressors MiR-125a-5p and MiR-125b. Hepatology 57:1055–1067
-
(2013)
Hepatology
, vol.57
, pp. 1055-1067
-
-
Kim, J.K.1
Noh, J.H.2
Jung, K.H.3
Eun, J.W.4
Bae, H.J.5
Kim, M.G.6
Chang, Y.G.7
Shen, Q.8
Park, W.S.9
Lee, J.Y.10
Borlak, J.11
Nam, S.W.12
-
113
-
-
84895835925
-
Forever young: SIRT3 a shield against mitochondrial meltdown, aging, and neurodegeneration
-
PID: 24046746
-
Kincaid B, Bossy-Wetzel E (2013) Forever young: SIRT3 a shield against mitochondrial meltdown, aging, and neurodegeneration. Front Aging Neurosci 5:48
-
(2013)
Front Aging Neurosci
, vol.5
, pp. 48
-
-
Kincaid, B.1
Bossy-Wetzel, E.2
-
114
-
-
84882265517
-
Growth hormone and melatonin prevent age-related alteration in apoptosis processes in the dentate gyrus of male rats
-
COI: 1:CAS:528:DC%2BC3sXht1yiur7E, PID: 23852044
-
Kireev RA, Vara E, Tresguerres JAF (2013) Growth hormone and melatonin prevent age-related alteration in apoptosis processes in the dentate gyrus of male rats. Biogerontology 14(4):431–442
-
(2013)
Biogerontology
, vol.14
, Issue.4
, pp. 431-442
-
-
Kireev, R.A.1
Vara, E.2
Tresguerres, J.A.F.3
-
115
-
-
34548394642
-
The effects of tetrahydrocurcumin and green tea polyphenol on the survival of male C57BL/6 mice
-
COI: 1:CAS:528:DC%2BD2sXpvVWqsbo%3D, PID: 17516143
-
Kitani K, Osawa T, Yokozawa T (2007) The effects of tetrahydrocurcumin and green tea polyphenol on the survival of male C57BL/6 mice. Biogerontology 8:567–573
-
(2007)
Biogerontology
, vol.8
, pp. 567-573
-
-
Kitani, K.1
Osawa, T.2
Yokozawa, T.3
-
116
-
-
0018644035
-
MAR1-a regulator of the HMa and HMalpha Loci in Sacchromyces cerevisiae
-
COI: 1:STN:280:DC%2BC3crpt1yiug%3D%3D, PID: 17248968
-
Klar AJ, Fogel S, Macleod K (1979) MAR1-a regulator of the HMa and HMalpha Loci in Sacchromyces cerevisiae. Genetics 93(1):37–50
-
(1979)
Genetics
, vol.93
, Issue.1
, pp. 37-50
-
-
Klar, A.J.1
Fogel, S.2
Macleod, K.3
-
117
-
-
84984820665
-
P66Shc-SIRT1 regulation of oxidative stress protects against cardio-cerebral vascular disease
-
Kong X, Guan J, Li J, Wei J, Wang R (2016) P66Shc-SIRT1 regulation of oxidative stress protects against cardio-cerebral vascular disease. Mol Neurobiol. doi:10.1007/s12035-016-0073-2
-
(2016)
Mol Neurobiol
-
-
Kong, X.1
Guan, J.2
Li, J.3
Wei, J.4
Wang, R.5
-
118
-
-
33749330500
-
Exercise, cognition, and the aging brain
-
PID: 16778001
-
Kramer AF, Erickson KI, Colcombe SJ (2006) Exercise, cognition, and the aging brain. J Appl Physiol 101(4):1237–1242
-
(2006)
J Appl Physiol
, vol.101
, Issue.4
, pp. 1237-1242
-
-
Kramer, A.F.1
Erickson, K.I.2
Colcombe, S.J.3
-
119
-
-
84856628731
-
Dietary obesity-associated Hif1alpha activation in adipocytes restricts fatty acid oxidation and energy expenditure via suppression of the Sirt2-NAD+ system
-
COI: 1:CAS:528:DC%2BC38XitlWgtLg%3D, PID: 22302938
-
Krishnan J, Danzer C, Simka T, Ukropec J, Walter KM, Kumpf S, Mirtschink P, Ukropcova B, Gasperikova D, Pedrazzini T, Krek W (2012) Dietary obesity-associated Hif1alpha activation in adipocytes restricts fatty acid oxidation and energy expenditure via suppression of the Sirt2-NAD+ system. Genes Dev 26(3):259–270
-
(2012)
Genes Dev
, vol.26
, Issue.3
, pp. 259-270
-
-
Krishnan, J.1
Danzer, C.2
Simka, T.3
Ukropec, J.4
Walter, K.M.5
Kumpf, S.6
Mirtschink, P.7
Ukropcova, B.8
Gasperikova, D.9
Pedrazzini, T.10
Krek, W.11
-
120
-
-
84911986242
-
Identification of serum sirtuins as novel noninvasive protein markers for frailty
-
COI: 1:CAS:528:DC%2BC2cXitVamtbjM, PID: 25100619
-
Kumar R, Mohan N, Upadhyay AD, Singh AP, Sahu V, Dwivedi S, Dey AB, Dey S (2014a) Identification of serum sirtuins as novel noninvasive protein markers for frailty. Aging Cell 13(6):975–980
-
(2014)
Aging Cell
, vol.13
, Issue.6
, pp. 975-980
-
-
Kumar, R.1
Mohan, N.2
Upadhyay, A.D.3
Singh, A.P.4
Sahu, V.5
Dwivedi, S.6
Dey, A.B.7
Dey, S.8
-
121
-
-
84902867247
-
P66Shc mediates increased platelet activation and aggregation in hypercholesterolemia
-
COI: 1:CAS:528:DC%2BC2cXpslWqurc%3D, PID: 24845561
-
Kumar S, Vikram A, Kim YR, Jacobs SJ, Irani K (2014b) P66Shc mediates increased platelet activation and aggregation in hypercholesterolemia. Biochem Biophys Res Commun 449(4):496–501
-
(2014)
Biochem Biophys Res Commun
, vol.449
, Issue.4
, pp. 496-501
-
-
Kumar, S.1
Vikram, A.2
Kim, Y.R.3
Jacobs, S.J.4
Irani, K.5
-
122
-
-
84906123510
-
Exercise training enhanced SIRT1 longevity signaling replaces the IGF1 survival pathway to attenuate aging-induced rat heart apoptosis
-
Lai CH, Ho TJ, Kuo WW, Day CH, Pai PY, Chung LC, Liao PH, Lin FH, Wu ET, Huang CY (2014) Exercise training enhanced SIRT1 longevity signaling replaces the IGF1 survival pathway to attenuate aging-induced rat heart apoptosis. Age (Dordr) 36(5):9706
-
(2014)
Age (Dordr)
, vol.36
, Issue.5
, pp. 9706
-
-
Lai, C.H.1
Ho, T.J.2
Kuo, W.W.3
Day, C.H.4
Pai, P.Y.5
Chung, L.C.6
Liao, P.H.7
Lin, F.H.8
Wu, E.T.9
Huang, C.Y.10
-
123
-
-
84866321536
-
Physiological and behavioural consequences of long-term moderate treadmill exercise
-
PID: 22472479
-
Lalanza JF, Sanchez-Roige S, Gagliano H, Fuentes S, Bayod S, Camins A, Pallàs M, Armario A, Escorihuela RM (2012) Physiological and behavioural consequences of long-term moderate treadmill exercise. Psychoneuroendocrinology 37(11):1745–1754
-
(2012)
Psychoneuroendocrinology
, vol.37
, Issue.11
, pp. 1745-1754
-
-
Lalanza, J.F.1
Sanchez-Roige, S.2
Gagliano, H.3
Fuentes, S.4
Bayod, S.5
Camins, A.6
Pallàs, M.7
Armario, A.8
Escorihuela, R.M.9
-
124
-
-
0037093346
-
Human SIR2 deacetylates p53 and antagonizes PML/p53-induced cellular senescence
-
COI: 1:CAS:528:DC%2BD38XktFChu7c%3D, PID: 12006491
-
Langley E, Pearson M, Faretta M, Bauer UM, Frye RA, Minucci S, Pelicci PG, Kouzarides T (2002) Human SIR2 deacetylates p53 and antagonizes PML/p53-induced cellular senescence. EMBO J 21(10):2383–2396
-
(2002)
EMBO J
, vol.21
, Issue.10
, pp. 2383-2396
-
-
Langley, E.1
Pearson, M.2
Faretta, M.3
Bauer, U.M.4
Frye, R.A.5
Minucci, S.6
Pelicci, P.G.7
Kouzarides, T.8
-
125
-
-
0028886492
-
Antihepatotoxic activity of icariin, a major constituent of Epimedium koreanum
-
COI: 1:CAS:528:DyaK28XotVGhsQ%3D%3D, PID: 8824946
-
Lee MK, Choi YJ, Sung SH, Shin DI, Kim JW, Kim YC (1995) Antihepatotoxic activity of icariin, a major constituent of Epimedium koreanum. Planta Med 61:523–526
-
(1995)
Planta Med
, vol.61
, pp. 523-526
-
-
Lee, M.K.1
Choi, Y.J.2
Sung, S.H.3
Shin, D.I.4
Kim, J.W.5
Kim, Y.C.6
-
127
-
-
84870292564
-
Cytosolic malate dehydrogenase regulates senescence in human fibroblasts
-
COI: 1:CAS:528:DC%2BC38XhsVCgtL3M, PID: 22971926
-
Lee SM, Dho SH, Ju SK, Maeng JS, Kim JY, Kwon KS (2012) Cytosolic malate dehydrogenase regulates senescence in human fibroblasts. Biogerontology 13(5):525–536
-
(2012)
Biogerontology
, vol.13
, Issue.5
, pp. 525-536
-
-
Lee, S.M.1
Dho, S.H.2
Ju, S.K.3
Maeng, J.S.4
Kim, J.Y.5
Kwon, K.S.6
-
128
-
-
70350365059
-
Human longevity and 11p15.5: a study in 1321 centenarians
-
PID: 19367319
-
Lescai F, Blanche H, Nebel A, Beekman M, Sahbatou M, Flachsbart F, Slagboom E, Schreiber S, Sorbi S, Passarino G, Franceschi C (2009) Human longevity and 11p15.5: a study in 1321 centenarians. Eur J Hum Genet 17(11):1515–1519
-
(2009)
Eur J Hum Genet
, vol.17
, Issue.11
, pp. 1515-1519
-
-
Lescai, F.1
Blanche, H.2
Nebel, A.3
Beekman, M.4
Sahbatou, M.5
Flachsbart, F.6
Slagboom, E.7
Schreiber, S.8
Sorbi, S.9
Passarino, G.10
Franceschi, C.11
-
129
-
-
84922355140
-
Curcumin induces oxidation-dependent cell cycle arrest mediated by SIRT7 inhibition of rDNA transcription in human aortic smooth muscle cells
-
COI: 1:CAS:528:DC%2BC2MXitVClurY%3D, PID: 25644192
-
Lewinska A, Wnuk M, Grabowska W, Zabek T, Semik E, Sikora E, Bielak-Żmijewska A (2015) Curcumin induces oxidation-dependent cell cycle arrest mediated by SIRT7 inhibition of rDNA transcription in human aortic smooth muscle cells. Toxicol Lett 233(3):227–238
-
(2015)
Toxicol Lett
, vol.233
, Issue.3
, pp. 227-238
-
-
Lewinska, A.1
Wnuk, M.2
Grabowska, W.3
Zabek, T.4
Semik, E.5
Sikora, E.6
Bielak-Żmijewska, A.7
-
130
-
-
33847793039
-
Sirtuin 2, a mammalian homolog of yeast silent information regulator-2 longevity regulator, is an oligodendroglial protein that deacetylates cell differentiation through deacetylating alpha-tubulin
-
Li W, Zhang B, Tang J, Cao Q, Wu Y, Wu C, Guo J, Ling EA, Liang F (2007) Sirtuin 2, a mammalian homolog of yeast silent information regulator-2 longevity regulator, is an oligodendroglial protein that deacetylates cell differentiation through deacetylating alpha-tubulin. J Neurosci 27:2602–2616
-
(2007)
J Neurosci
, vol.27
, pp. 2602-2616
-
-
Li, W.1
Zhang, B.2
Tang, J.3
Cao, Q.4
Wu, Y.5
Wu, C.6
Guo, J.7
Ling, E.A.8
Liang, F.9
-
131
-
-
43149118368
-
Regulation of WRN protein cellular localization and enzymatic activities by SIRT1-mediated deacetylation
-
COI: 1:CAS:528:DC%2BD1cXjt1elsr4%3D, PID: 18203716
-
Li K, Casta A, Wang R, Lozada E, Fan W, Kane S, Ge Q, Gu W, Orren D, Luo J (2008) Regulation of WRN protein cellular localization and enzymatic activities by SIRT1-mediated deacetylation. J Biol Chem 283:7590–7598
-
(2008)
J Biol Chem
, vol.283
, pp. 7590-7598
-
-
Li, K.1
Casta, A.2
Wang, R.3
Lozada, E.4
Fan, W.5
Kane, S.6
Ge, Q.7
Gu, W.8
Orren, D.9
Luo, J.10
-
132
-
-
77956295588
-
p53-induced growth arrest is regulated by the mitochondrial SirT3 deacetylase
-
PID: 20463968
-
Li S, Banck M, Mujtaba S, Zhou MM, Sugrue MM, Walsh MJ (2010) p53-induced growth arrest is regulated by the mitochondrial SirT3 deacetylase. PLoS ONE 5:e10486
-
(2010)
PLoS ONE
, vol.5
-
-
Li, S.1
Banck, M.2
Mujtaba, S.3
Zhou, M.M.4
Sugrue, M.M.5
Walsh, M.J.6
-
134
-
-
80053385974
-
Curcumin-mediated lifespan extension in Caenorhabditis elegans
-
COI: 1:CAS:528:DC%2BC3MXht1OisrjP, PID: 21855561
-
Liao VH, Yu CW, Chu YJ, Li WH, Hsieh YC, Wang TT (2011) Curcumin-mediated lifespan extension in Caenorhabditis elegans. Mech Ageing Dev 132(10):480–487
-
(2011)
Mech Ageing Dev
, vol.132
, Issue.10
, pp. 480-487
-
-
Liao, V.H.1
Yu, C.W.2
Chu, Y.J.3
Li, W.H.4
Hsieh, Y.C.5
Wang, T.T.6
-
135
-
-
0034703217
-
Requirement of NAD and SIR2 for life-span extension by calorie restriction in Saccharomyces cerevisiae
-
COI: 1:CAS:528:DC%2BD3cXmvVClsbc%3D, PID: 11000115
-
Lin SJ, Defossez PA, Guarente L (2000) Requirement of NAD and SIR2 for life-span extension by calorie restriction in Saccharomyces cerevisiae. Science 289(5487):2126–2128
-
(2000)
Science
, vol.289
, Issue.5487
, pp. 2126-2128
-
-
Lin, S.J.1
Defossez, P.A.2
Guarente, L.3
-
136
-
-
84887412525
-
SIRT5 desuccinylates and activates SOD1 to eliminate ROS
-
COI: 1:CAS:528:DC%2BC3sXhs1yqtbrO, PID: 24140062
-
Lin ZF, Xu HB, Wang JY, Lin Q, Ruan Z, Liu FB, Jin W, Huang HH, Chen X (2013) SIRT5 desuccinylates and activates SOD1 to eliminate ROS. Biochem Biophys Res Commun 441(1):191–195
-
(2013)
Biochem Biophys Res Commun
, vol.441
, Issue.1
, pp. 191-195
-
-
Lin, Z.F.1
Xu, H.B.2
Wang, J.Y.3
Lin, Q.4
Ruan, Z.5
Liu, F.B.6
Jin, W.7
Huang, H.H.8
Chen, X.9
-
137
-
-
84906462901
-
Resveratrol enhanced FOXO3 phosphorylation via synergetic activation of SIRT1 and PI3K/Akt signaling to improve the effects of exercise in elderly rat hearts
-
Lin CH, Lin CC, Ting WJ, Pai PY, Kuo CH, Ho TJ, Kuo WW, Chang CH, Huang CY, Lin WT (2014) Resveratrol enhanced FOXO3 phosphorylation via synergetic activation of SIRT1 and PI3K/Akt signaling to improve the effects of exercise in elderly rat hearts. Age (Dordr) 36(5):9705
-
(2014)
Age (Dordr)
, vol.36
, Issue.5
, pp. 9705
-
-
Lin, C.H.1
Lin, C.C.2
Ting, W.J.3
Pai, P.Y.4
Kuo, C.H.5
Ho, T.J.6
Kuo, W.W.7
Chang, C.H.8
Huang, C.Y.9
Lin, W.T.10
-
138
-
-
84980349950
-
Sirt1 decreased adipose inflammation by interacting with Akt2 and inhibiting mTOR/S6K1 pathway in mice
-
COI: 1:CAS:528:DC%2BC28Xht1Oktb7F, PID: 27317762
-
Liu Z, Gan L, Liu G, Chen Y, Wu T, Feng F, Sun C (2016) Sirt1 decreased adipose inflammation by interacting with Akt2 and inhibiting mTOR/S6K1 pathway in mice. J Lipid Res 57(8):1373–1381
-
(2016)
J Lipid Res
, vol.57
, Issue.8
, pp. 1373-1381
-
-
Liu, Z.1
Gan, L.2
Liu, G.3
Chen, Y.4
Wu, T.5
Feng, F.6
Sun, C.7
-
139
-
-
84928243408
-
Interventions to slow aging in humans: are we ready?
-
COI: 1:CAS:528:DC%2BC2MXmvVyqu7k%3D, PID: 25902704
-
Longo VD, Antebi A, Bartke A, Barzilai N, Brown-Borg HM, Caruso C, Curiel TJ, de Cabo R, Franceschi C, Gems D, Ingram DK, Johnson TE, Kennedy BK, Kenyon C, Klein S, Kopchick JJ, Lepperdinger G, Madeo F, Mirisola MG, Mitchell JR, Passarino G, Rudolph KL, Sedivy JM, Shadel GS, Sinclair DA, Spindler SR, Suh Y, Vijg J, Vinciguerra M, Fontana L (2015) Interventions to slow aging in humans: are we ready? Aging Cell 14(4):497–510
-
(2015)
Aging Cell
, vol.14
, Issue.4
, pp. 497-510
-
-
Longo, V.D.1
Antebi, A.2
Bartke, A.3
Barzilai, N.4
Brown-Borg, H.M.5
Caruso, C.6
Curiel, T.J.7
de Cabo, R.8
Franceschi, C.9
Gems, D.10
Ingram, D.K.11
Johnson, T.E.12
Kennedy, B.K.13
Kenyon, C.14
Klein, S.15
Kopchick, J.J.16
Lepperdinger, G.17
Madeo, F.18
Mirisola, M.G.19
Mitchell, J.R.20
Passarino, G.21
Rudolph, K.L.22
Sedivy, J.M.23
Shadel, G.S.24
Sinclair, D.A.25
Spindler, S.R.26
Suh, Y.27
Vijg, J.28
Vinciguerra, M.29
Fontana, L.30
more..
-
140
-
-
84897538335
-
Modulating the p66shc signaling pathway with protocatechuic acid protects the intestine from ischemiareperfusion injury and alleviates secondary liver damage
-
Ma L, Wang G, Chen Z, Li Z, Yao J, Zhao H, Wang S, Ma Z, Chang H, Tian X (2014) Modulating the p66shc signaling pathway with protocatechuic acid protects the intestine from ischemiareperfusion injury and alleviates secondary liver damage. Sci World J 2014:387640
-
(2014)
Sci World J
, vol.2014
, pp. 387640
-
-
Ma, L.1
Wang, G.2
Chen, Z.3
Li, Z.4
Yao, J.5
Zhao, H.6
Wang, S.7
Ma, Z.8
Chang, H.9
Tian, X.10
-
141
-
-
84863974838
-
Sirtuin 6 (SIRT6) rescues the decline of homologous recombination repair during replicative senescence
-
Mao Z, Tian X, Van Meter M, Ke Z, Gorbunova V, Seluanov A (2011) Sirtuin 6 (SIRT6) rescues the decline of homologous recombination repair during replicative senescence. Proc Natl Acad Sci USA 109(29):11800–11805
-
(2011)
Proc Natl Acad Sci USA
, vol.109
, Issue.29
, pp. 11800-11805
-
-
Mao, Z.1
Tian, X.2
Van Meter, M.3
Ke, Z.4
Gorbunova, V.5
Seluanov, A.6
-
142
-
-
84959862066
-
Long live FOXO: unraveling the role of FOXO proteins in aging and longevity
-
COI: 1:CAS:528:DC%2BC2MXhvFKgs7vJ, PID: 26643314
-
Martins R, Lithgow GJ, Link W (2016) Long live FOXO: unraveling the role of FOXO proteins in aging and longevity. Aging Cell 15(2):196–207
-
(2016)
Aging Cell
, vol.15
, Issue.2
, pp. 196-207
-
-
Martins, R.1
Lithgow, G.J.2
Link, W.3
-
143
-
-
78049268948
-
Aging and exercise affect the level of protein acetylation and SIRT1 activity in cerebellum of male rats
-
COI: 1:CAS:528:DC%2BC3cXhtlSjt7nF, PID: 20467811
-
Marton O, Koltai E, Nyakas C, Bakonyi T, Zenteno-Savin T, Kumagai S, Goto S, Radak Z (2010) Aging and exercise affect the level of protein acetylation and SIRT1 activity in cerebellum of male rats. Biogerontology 11:679–686
-
(2010)
Biogerontology
, vol.11
, pp. 679-686
-
-
Marton, O.1
Koltai, E.2
Nyakas, C.3
Bakonyi, T.4
Zenteno-Savin, T.5
Kumagai, S.6
Goto, S.7
Radak, Z.8
-
144
-
-
22744445281
-
Overview of caloric restriction and ageing
-
COI: 1:CAS:528:DC%2BD2MXmvVGjtr0%3D, PID: 15885745
-
Masoro EJ (2005) Overview of caloric restriction and ageing. Mech Ageing Dev 126(9):913–922
-
(2005)
Mech Ageing Dev
, vol.126
, Issue.9
, pp. 913-922
-
-
Masoro, E.J.1
-
145
-
-
23844485211
-
Acetylation of Foxo1 alters its DNA-binding ability and sensitivity to phosphorylation
-
COI: 1:CAS:528:DC%2BD2MXoslKit74%3D, PID: 16076959
-
Matsuzaki H, Daitoku H, Hatta M, Aoyama H, Yoshimochi K, Fukamizu A (2005) Acetylation of Foxo1 alters its DNA-binding ability and sensitivity to phosphorylation. Proc Natl Acad Sci USA 102:11278–11283
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 11278-11283
-
-
Matsuzaki, H.1
Daitoku, H.2
Hatta, M.3
Aoyama, H.4
Yoshimochi, K.5
Fukamizu, A.6
-
146
-
-
0037207475
-
The mammalian SIR2α protein has a role in embryogenesis and gametogenesis
-
COI: 1:CAS:528:DC%2BD3sXhtVOlsg%3D%3D, PID: 12482959
-
McBurney MW, Yang X, Jardine K, Hixon M, Boekelheide K, Webb JR, Lansdorp PM, Lemieux M (2003) The mammalian SIR2α protein has a role in embryogenesis and gametogenesis. Mol Cell Biol 23:38–54
-
(2003)
Mol Cell Biol
, vol.23
, pp. 38-54
-
-
McBurney, M.W.1
Yang, X.2
Jardine, K.3
Hixon, M.4
Boekelheide, K.5
Webb, J.R.6
Lansdorp, P.M.7
Lemieux, M.8
-
147
-
-
0030915211
-
Physical activity as a factor in the action of dietary restriction on aging: effects in Fischer 344 rats
-
COI: 1:CAS:528:DyaK2sXjtFKjsb8%3D
-
McCarter RJ, Shimokawa I, Ikeno Y, Higami Y, Hubbard GB, Yu BP, McMahan CA (1997) Physical activity as a factor in the action of dietary restriction on aging: effects in Fischer 344 rats. Aging (Milano) 9:73–79
-
(1997)
Aging (Milano)
, vol.9
, pp. 73-79
-
-
McCarter, R.J.1
Shimokawa, I.2
Ikeno, Y.3
Higami, Y.4
Hubbard, G.B.5
Yu, B.P.6
McMahan, C.A.7
-
148
-
-
7644226719
-
NAD+ modulates p53 DNA binding specificity and function
-
COI: 1:CAS:528:DC%2BD2cXpslOnu7g%3D, PID: 15509798
-
McLure KG, Takagi M, Kastan MB (2004) NAD+ modulates p53 DNA binding specificity and function. Mol Cell Biol 24:9958–9967
-
(2004)
Mol Cell Biol
, vol.24
, pp. 9958-9967
-
-
McLure, K.G.1
Takagi, M.2
Kastan, M.B.3
-
149
-
-
0042691506
-
Autophagy genes are essential for dauer development and life-span extension in C. elegans
-
COI: 1:CAS:528:DC%2BD3sXmvFelurw%3D, PID: 12958363
-
Melendez A, Talloczy Z, Seaman M, Eskelinen EL, Hall DH, Levine B (2003) Autophagy genes are essential for dauer development and life-span extension in C. elegans. Science 301:1387–1391
-
(2003)
Science
, vol.301
, pp. 1387-1391
-
-
Melendez, A.1
Talloczy, Z.2
Seaman, M.3
Eskelinen, E.L.4
Hall, D.H.5
Levine, B.6
-
150
-
-
84924866970
-
SRT2104 extends survival of male mice on a standard diet and preserves bone and muscle mass
-
COI: 1:CAS:528:DC%2BC2cXhsFOnsrbK, PID: 24931715
-
Mercken EM, Mitchell SJ, Martin-Montalvo A, Minor RK, Almeida M, Gomes AP, Scheibye-Knudsen M, Palacios HH, Licata JJ, Zhang Y, Becker KG, Khraiwesh H, González-Reyes JA, Villalba JM, Baur JA, Elliott P, Westphal C, Vlasuk GP, Ellis JL, Sinclair DA, Bernier M, de Cabo R (2014) SRT2104 extends survival of male mice on a standard diet and preserves bone and muscle mass. Aging Cell 13(5):787–796
-
(2014)
Aging Cell
, vol.13
, Issue.5
, pp. 787-796
-
-
Mercken, E.M.1
Mitchell, S.J.2
Martin-Montalvo, A.3
Minor, R.K.4
Almeida, M.5
Gomes, A.P.6
Scheibye-Knudsen, M.7
Palacios, H.H.8
Licata, J.J.9
Zhang, Y.10
Becker, K.G.11
Khraiwesh, H.12
González-Reyes, J.A.13
Villalba, J.M.14
Baur, J.A.15
Elliott, P.16
Westphal, C.17
Vlasuk, G.P.18
Ellis, J.L.19
Sinclair, D.A.20
Bernier, M.21
de Cabo, R.22
more..
-
151
-
-
34249083199
-
Sirtuins in mammals: insights into their biological function
-
COI: 1:CAS:528:DC%2BD2sXks1ansr4%3D, PID: 17447894
-
Michan S, Sinclair D (2007) Sirtuins in mammals: insights into their biological function. Biochem J 404:1–13
-
(2007)
Biochem J
, vol.404
, pp. 1-13
-
-
Michan, S.1
Sinclair, D.2
-
152
-
-
41349090663
-
SIRT6 is a histone H3 lysine 9 deacetylase that modulates telomeric chromatin
-
COI: 1:CAS:528:DC%2BD1cXjslCnurs%3D, PID: 18337721
-
Michishita E, McCord RA, Berber E, Kioi M, Padilla-Nash H, Damian M, Cheung P, Kusumoto R, Kawahara TL, Barrett JC, Chang HY, Bohr VA, Ried T, Gozani O, Chua KF (2008) SIRT6 is a histone H3 lysine 9 deacetylase that modulates telomeric chromatin. Nature 452(7186):492–496
-
(2008)
Nature
, vol.452
, Issue.7186
, pp. 492-496
-
-
Michishita, E.1
McCord, R.A.2
Berber, E.3
Kioi, M.4
Padilla-Nash, H.5
Damian, M.6
Cheung, P.7
Kusumoto, R.8
Kawahara, T.L.9
Barrett, J.C.10
Chang, H.Y.11
Bohr, V.A.12
Ried, T.13
Gozani, O.14
Chua, K.F.15
-
153
-
-
84905045240
-
Low insulin-like growth factor-1 level predicts survival in humans with exceptional longevity
-
COI: 1:CAS:528:DC%2BC2cXht1aksrzP, PID: 24618355
-
Milman S, Atzmon G, Huffman DM, Wan J, Crandall JP, Cohen P, Barzilai N (2014) Low insulin-like growth factor-1 level predicts survival in humans with exceptional longevity. Aging Cell 13:769–771
-
(2014)
Aging Cell
, vol.13
, pp. 769-771
-
-
Milman, S.1
Atzmon, G.2
Huffman, D.M.3
Wan, J.4
Crandall, J.P.5
Cohen, P.6
Barzilai, N.7
-
154
-
-
84859909860
-
SRT1720 improves survival and healthspan of obese mice
-
PID: 22355589
-
Minor RK, Baur JA, Gomes AP, Ward TM, Csiszar A, Mercken EM, Abdelmohsen K, Shin YK, Canto C, Scheibye-Knudsen M, Krawczyk M, Irusta PM, MartinMontalvo A, Hubbard BP, Zhang Y, Lehrmann E, White AA, Price NL, Swindell WR, Pearson KJ, Becker KG, Bohr VA, Gorospe M, Egan JM, Talan MI, Auwerx J, Westphal CH, Ellis JL, Ungvari Z, Vlasuk GP, Elliott PJ, Sinclair DA, de Cabo R (2011) SRT1720 improves survival and healthspan of obese mice. Sci Rep 1:70
-
(2011)
Sci Rep
, vol.1
, pp. 70
-
-
Minor, R.K.1
Baur, J.A.2
Gomes, A.P.3
Ward, T.M.4
Csiszar, A.5
Mercken, E.M.6
Abdelmohsen, K.7
Shin, Y.K.8
Canto, C.9
Scheibye-Knudsen, M.10
Krawczyk, M.11
Irusta, P.M.12
MartinMontalvo, A.13
Hubbard, B.P.14
Zhang, Y.15
Lehrmann, E.16
White, A.A.17
Price, N.L.18
Swindell, W.R.19
Pearson, K.J.20
Becker, K.G.21
Bohr, V.A.22
Gorospe, M.23
Egan, J.M.24
Talan, M.I.25
Auwerx, J.26
Westphal, C.H.27
Ellis, J.L.28
Ungvari, Z.29
Vlasuk, G.P.30
Elliott, P.J.31
Sinclair, D.A.32
de Cabo, R.33
more..
-
155
-
-
69349090064
-
Age effects on the regulation of adult hippocampal neurogenesis by physical activity and environmental enrichment in the APP23 mouse model of Alzheimer disease
-
COI: 1:CAS:528:DC%2BD1MXhtlyqtr7I, PID: 19219917
-
Mirochnic S, Wolf S, Staufenbiel M, Kempermann G (2009) Age effects on the regulation of adult hippocampal neurogenesis by physical activity and environmental enrichment in the APP23 mouse model of Alzheimer disease. Hippocampus 19(10):1008–1018
-
(2009)
Hippocampus
, vol.19
, Issue.10
, pp. 1008-1018
-
-
Mirochnic, S.1
Wolf, S.2
Staufenbiel, M.3
Kempermann, G.4
-
156
-
-
84903532543
-
Evidence for a novel antioxidant function and isoform-specific regulation of the human p66Shc gene
-
PID: 24807908
-
Miyazawa M, Tsuji Y (2014) Evidence for a novel antioxidant function and isoform-specific regulation of the human p66Shc gene. Mol Biol Cell 25(13):2116–2127
-
(2014)
Mol Biol Cell
, vol.25
, Issue.13
, pp. 2116-2127
-
-
Miyazawa, M.1
Tsuji, Y.2
-
157
-
-
84874108083
-
Seven sirtuins for seven deadly diseases of aging
-
COI: 1:CAS:528:DC%2BC38Xhs1KqsrrE, PID: 23104101
-
Morris BJ (2013) Seven sirtuins for seven deadly diseases of aging. Free Radic Biol Med 56:133–171
-
(2013)
Free Radic Biol Med
, vol.56
, pp. 133-171
-
-
Morris, B.J.1
-
158
-
-
84863088886
-
Curcumin induces permanent growth arrest of human colon cancer cells: link between senescence and autophagy
-
COI: 1:CAS:528:DC%2BC38XhtVShu7bP, PID: 22613224
-
Mosieniak G, Adamowicz M, Alster O, Jaskowiak H, Szczepankiewicz AA, Wilczynski GM, Ciechomska IA, Sikora E (2012) Curcumin induces permanent growth arrest of human colon cancer cells: link between senescence and autophagy. Mech Ageing Dev 133(6):444–455
-
(2012)
Mech Ageing Dev
, vol.133
, Issue.6
, pp. 444-455
-
-
Mosieniak, G.1
Adamowicz, M.2
Alster, O.3
Jaskowiak, H.4
Szczepankiewicz, A.A.5
Wilczynski, G.M.6
Ciechomska, I.A.7
Sikora, E.8
-
159
-
-
84959287499
-
Curcumin-treated cancer cells show mitotic disturbances leading to growth arrest and induction of senescence phenotype
-
COI: 1:CAS:528:DC%2BC28Xjs1yhtbo%3D, PID: 26916504
-
Mosieniak G, Sliwinska MA, Przybylska D, Grabowska W, Sunderland P, Bielak-Zmijewska A, Sikora E (2016) Curcumin-treated cancer cells show mitotic disturbances leading to growth arrest and induction of senescence phenotype. Int J Biochem Cell Biol 74:33–43
-
(2016)
Int J Biochem Cell Biol
, vol.74
, pp. 33-43
-
-
Mosieniak, G.1
Sliwinska, M.A.2
Przybylska, D.3
Grabowska, W.4
Sunderland, P.5
Bielak-Zmijewska, A.6
Sikora, E.7
-
160
-
-
31044445366
-
Genomic instability and aging-like phenotype in the absence of mammalian SIRT6
-
COI: 1:CAS:528:DC%2BD28Xht1KktLc%3D, PID: 16439206
-
Mostoslavsky R, Chua KF, Lombard DB, Pang WW, Fischer MR, Gellon L, Liu P, Mostoslavsky G, Franco S, Murphy MM, Mills KD, Patel P, Hsu JT, Hong AL, Ford E, Cheng HL, Kennedy C, Nunez N, Bronson R, Frendewey D, Auerbach W, Valenzuela D, Karow M, Hottiger MO, Hursting S, Barrett JC, Guarente L, Mulligan R, Demple B, Yancopoulos GD, Alt FW (2006) Genomic instability and aging-like phenotype in the absence of mammalian SIRT6. Cell 124(2):315–329
-
(2006)
Cell
, vol.124
, Issue.2
, pp. 315-329
-
-
Mostoslavsky, R.1
Chua, K.F.2
Lombard, D.B.3
Pang, W.W.4
Fischer, M.R.5
Gellon, L.6
Liu, P.7
Mostoslavsky, G.8
Franco, S.9
Murphy, M.M.10
Mills, K.D.11
Patel, P.12
Hsu, J.T.13
Hong, A.L.14
Ford, E.15
Cheng, H.L.16
Kennedy, C.17
Nunez, N.18
Bronson, R.19
Frendewey, D.20
Auerbach, W.21
Valenzuela, D.22
Karow, M.23
Hottiger, M.O.24
Hursting, S.25
Barrett, J.C.26
Guarente, L.27
Mulligan, R.28
Demple, B.29
Yancopoulos, G.D.30
Alt, F.W.31
more..
-
161
-
-
78649872952
-
Life span extension by resveratrol, rapamycin and metformin: the promise of dietary restriction mimetics for an healthy aging
-
COI: 1:CAS:528:DC%2BC3cXhtl2msLjP, PID: 20848587
-
Mouchiroud L, Molin L, Dalliere N, Solari F (2010) Life span extension by resveratrol, rapamycin and metformin: the promise of dietary restriction mimetics for an healthy aging. BioFactors 36:377–382
-
(2010)
BioFactors
, vol.36
, pp. 377-382
-
-
Mouchiroud, L.1
Molin, L.2
Dalliere, N.3
Solari, F.4
-
162
-
-
67649669220
-
Suppression of the aging-associated decline in physical performance by a combination of resveratrol intake and habitual exercise in senescence-accelerated mice
-
COI: 1:CAS:528:DC%2BD1MXnsFCgu7w%3D, PID: 18830683
-
Murase T, Haramizu S, Ota N, Hase T (2009) Suppression of the aging-associated decline in physical performance by a combination of resveratrol intake and habitual exercise in senescence-accelerated mice. Biogerontology 10:423–434
-
(2009)
Biogerontology
, vol.10
, pp. 423-434
-
-
Murase, T.1
Haramizu, S.2
Ota, N.3
Hase, T.4
-
163
-
-
43049169926
-
Epigenetic control of rDNA loci in response to intracellular energy status
-
COI: 1:CAS:528:DC%2BD1cXmsVOrurg%3D, PID: 18485871
-
Murayama A, Ohmori K, Fujimura A, Ohmori K, Fujimura A, Minami H, Yasuzawa-Tanaka K, Kuroda T, Oie S, Daitoku H, Okuwaki M, Nagata K, Fukamizu A, Kimura K, Shimizu T, Yanagisawa J (2008) Epigenetic control of rDNA loci in response to intracellular energy status. Cell 133:627–639
-
(2008)
Cell
, vol.133
, pp. 627-639
-
-
Murayama, A.1
Ohmori, K.2
Fujimura, A.3
Ohmori, K.4
Fujimura, A.5
Minami, H.6
Yasuzawa-Tanaka, K.7
Kuroda, T.8
Oie, S.9
Daitoku, H.10
Okuwaki, M.11
Nagata, K.12
Fukamizu, A.13
Kimura, K.14
Shimizu, T.15
Yanagisawa, J.16
-
164
-
-
0035868764
-
Acetylation of TAF(I)68, a subunit of TIF-IB/SL1, activates RNA polymerase I transcription
-
COI: 1:CAS:528:DC%2BD3MXisVCksbg%3D, PID: 11250901
-
Muth V, Nadaud S, Grummt I, Voit R (2001) Acetylation of TAF(I)68, a subunit of TIF-IB/SL1, activates RNA polymerase I transcription. EMBO J 20:1353–1362
-
(2001)
EMBO J
, vol.20
, pp. 1353-1362
-
-
Muth, V.1
Nadaud, S.2
Grummt, I.3
Voit, R.4
-
165
-
-
79952806932
-
Sirtuins at a glance
-
COI: 1:CAS:528:DC%2BC3MXkvVOrtbY%3D, PID: 21378304
-
Nakagawa T, Guarente L (2011) Sirtuins at a glance. J Cell Sci 124:833–838
-
(2011)
J Cell Sci
, vol.124
, pp. 833-838
-
-
Nakagawa, T.1
Guarente, L.2
-
166
-
-
56749156405
-
SIRT1 redistribution on chromatin promotes genomic stability but alters gene expression during aging
-
COI: 1:CAS:528:DC%2BD1cXhsV2jtr%2FF, PID: 19041753
-
Oberdoerffer P, Michan S, McVay M, Mostoslavsky R, Vann J, Park SK, Hartlerode A, Stegmuller J, Hafner A, Loerch P, Wright SM, Mills KD, Bonni A, Yankner BA, Scully R, Prolla TA, Alt FW, Sinclair DA (2008) SIRT1 redistribution on chromatin promotes genomic stability but alters gene expression during aging. Cell 135(5):907–918
-
(2008)
Cell
, vol.135
, Issue.5
, pp. 907-918
-
-
Oberdoerffer, P.1
Michan, S.2
McVay, M.3
Mostoslavsky, R.4
Vann, J.5
Park, S.K.6
Hartlerode, A.7
Stegmuller, J.8
Hafner, A.9
Loerch, P.10
Wright, S.M.11
Mills, K.D.12
Bonni, A.13
Yankner, B.A.14
Scully, R.15
Prolla, T.A.16
Alt, F.W.17
Sinclair, D.A.18
-
167
-
-
31144462116
-
Effect of curcumin on atherosclerosis in apoE/LDLR-double knockout mice
-
COI: 1:CAS:528:DC%2BD28XnvVagtQ%3D%3D, PID: 16391419
-
Olszanecki R, Jawień J, Gajda M, Mateuszuk L, Gebska A, Korabiowska M, Chłopicki S, Korbut R (2005) Effect of curcumin on atherosclerosis in apoE/LDLR-double knockout mice. J Physiol Pharmacol 56(4):627–635
-
(2005)
J Physiol Pharmacol
, vol.56
, Issue.4
, pp. 627-635
-
-
Olszanecki, R.1
Jawień, J.2
Gajda, M.3
Mateuszuk, L.4
Gebska, A.5
Korabiowska, M.6
Chłopicki, S.7
Korbut, R.8
-
168
-
-
51649106480
-
Cilostazol inhibits oxidative stress-induced premature senescence via upregulation of Sirt1 in human endothelial cells
-
COI: 1:CAS:528:DC%2BD1cXpvFKhtrc%3D, PID: 18556572
-
Ota H, Eto M, Kano MR, Ogawa S, Iijima K, Akishita M, Ouchi Y (2008) Cilostazol inhibits oxidative stress-induced premature senescence via upregulation of Sirt1 in human endothelial cells. Arterioscler Thromb Vasc Biol 28:1634–1639
-
(2008)
Arterioscler Thromb Vasc Biol
, vol.28
, pp. 1634-1639
-
-
Ota, H.1
Eto, M.2
Kano, M.R.3
Ogawa, S.4
Iijima, K.5
Akishita, M.6
Ouchi, Y.7
-
169
-
-
78149285838
-
Induction of endothelial nitric oxide synthase, SIRT1, and catalase by statins inhibits endothelial senescence through the Akt pathway
-
COI: 1:CAS:528:DC%2BC3cXhtlSqtbzP, PID: 20705918
-
Ota H, Eto M, Kano MR, Kahyo T, Setou M, Ogawa S, Iijima K, Akishita M, Ouchi Y (2010) Induction of endothelial nitric oxide synthase, SIRT1, and catalase by statins inhibits endothelial senescence through the Akt pathway. Arterioscler Thromb Vasc Biol 30:2205–2211
-
(2010)
Arterioscler Thromb Vasc Biol
, vol.30
, pp. 2205-2211
-
-
Ota, H.1
Eto, M.2
Kano, M.R.3
Kahyo, T.4
Setou, M.5
Ogawa, S.6
Iijima, K.7
Akishita, M.8
Ouchi, Y.9
-
170
-
-
78650747994
-
SIRT1 contributes to telomere maintenance and augments global homologous recombination
-
COI: 1:CAS:528:DC%2BC3MXis1WjsQ%3D%3D, PID: 21187328
-
Palacios JA, Herranz D, De Bonis ML, Velasco S, Serrano M, Blasco MA (2010) SIRT1 contributes to telomere maintenance and augments global homologous recombination. J Cell Biol 191(7):1299–1313
-
(2010)
J Cell Biol
, vol.191
, Issue.7
, pp. 1299-1313
-
-
Palacios, J.A.1
Herranz, D.2
De Bonis, M.L.3
Velasco, S.4
Serrano, M.5
Blasco, M.A.6
-
171
-
-
84957888485
-
Oligonol promotes anti-aging pathways via modulation of SIRT1-AMPK-autophagy pathway
-
PID: 26865910
-
Park S, Seong R, Kim J, Son S, Kim Y, Yokozawa T, Shin OS (2016) Oligonol promotes anti-aging pathways via modulation of SIRT1-AMPK-autophagy pathway. Nutr Res Pract 10(1):3–10
-
(2016)
Nutr Res Pract
, vol.10
, Issue.1
, pp. 3-10
-
-
Park, S.1
Seong, R.2
Kim, J.3
Son, S.4
Kim, Y.5
Yokozawa, T.6
Shin, O.S.7
-
172
-
-
84155163883
-
Effects of treadmill exercise and training frequency on anabolic signaling pathways in the skeletal muscle of aged rats
-
COI: 1:CAS:528:DC%2BC3MXhs12htr%2FK, PID: 22015326
-
Pasini E, Le Douairon Lahaye S, Flati V, Assanelli D, Corsetti G, Speca S, Bernabei R, Calvani R, Marzetti E (2012) Effects of treadmill exercise and training frequency on anabolic signaling pathways in the skeletal muscle of aged rats. Exp Gerontol 47(1):23–28
-
(2012)
Exp Gerontol
, vol.47
, Issue.1
, pp. 23-28
-
-
Pasini, E.1
Le Douairon, L.S.2
Flati, V.3
Assanelli, D.4
Corsetti, G.5
Speca, S.6
Bernabei, R.7
Calvani, R.8
Marzetti, E.9
-
173
-
-
84940976163
-
Sirtuin regulation in aging and injury
-
COI: 1:CAS:528:DC%2BC2MXhsVajsrfN, PID: 26303641
-
Poulose N, Raju R (2015) Sirtuin regulation in aging and injury. Biochim Biophys Acta 1852:2442–2455
-
(2015)
Biochim Biophys Acta
, vol.1852
, pp. 2442-2455
-
-
Poulose, N.1
Raju, R.2
-
174
-
-
77953762857
-
Polyphenols and aging
-
COI: 1:CAS:528:DC%2BC3cXhsVKisLzM, PID: 20298168
-
Queen BL, Tollefsbol TO (2010) Polyphenols and aging. Curr Aging Sci 3(1):34–42
-
(2010)
Curr Aging Sci
, vol.3
, Issue.1
, pp. 34-42
-
-
Queen, B.L.1
Tollefsbol, T.O.2
-
175
-
-
37849004479
-
Systemic adaptation to oxidative challenge induced by regular exercise
-
COI: 1:CAS:528:DC%2BD1cXlvVygtw%3D%3D, PID: 18191751
-
Radak Z, Chung HY, Goto S (2008) Systemic adaptation to oxidative challenge induced by regular exercise. Free Radic Biol Med 44:153–159
-
(2008)
Free Radic Biol Med
, vol.44
, pp. 153-159
-
-
Radak, Z.1
Chung, H.Y.2
Goto, S.3
-
176
-
-
84961289051
-
Caloric restriction, resveratrol and melatonin: role of SIRT1 and implications for aging and related-diseases
-
PID: 25824609
-
Ramis MR, Esteban S, Miralles A, Tan DX, Reiter RJ (2015) Caloric restriction, resveratrol and melatonin: role of SIRT1 and implications for aging and related-diseases. Mech Ageing Dev 146–148:28–41
-
(2015)
Mech Ageing Dev
, vol.146-148
, pp. 28-41
-
-
Ramis, M.R.1
Esteban, S.2
Miralles, A.3
Tan, D.X.4
Reiter, R.J.5
-
177
-
-
84860356570
-
Rationale and methods of discovering hormetins as drugs for healthy ageing
-
COI: 1:CAS:528:DC%2BC38XmtlCqs70%3D, PID: 22509769
-
Rattan SI (2012) Rationale and methods of discovering hormetins as drugs for healthy ageing. Expert Opin Drug Discov 7(5):439–448
-
(2012)
Expert Opin Drug Discov
, vol.7
, Issue.5
, pp. 439-448
-
-
Rattan, S.I.1
-
178
-
-
84941600539
-
Curcumin treatment enhances the effect of exercise on mitochondrial biogenesis in skeletal muscle by increasing cAMP levels
-
PID: 26278015
-
Ray Hamidie RD, Yamada T, Ishizawa R, Saito Y, Masuda K (2015) Curcumin treatment enhances the effect of exercise on mitochondrial biogenesis in skeletal muscle by increasing cAMP levels. Metabolism 64(10):1334–1347
-
(2015)
Metabolism
, vol.64
, Issue.10
, pp. 1334-1347
-
-
Ray Hamidie, R.D.1
Yamada, T.2
Ishizawa, R.3
Saito, Y.4
Masuda, K.5
-
179
-
-
8644224064
-
Sir2 mediates longevity in the fly through a pathway related to calorie restriction
-
COI: 1:CAS:528:DC%2BD2cXhtVGis77E, PID: 15520384
-
Rogina B, Helfand SL (2004) Sir2 mediates longevity in the fly through a pathway related to calorie restriction. Proc Natl Acad Sci USA 101(45):15998–16003
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, Issue.45
, pp. 15998-16003
-
-
Rogina, B.1
Helfand, S.L.2
-
180
-
-
76749124470
-
Healthy brain aging: role of exercise and physical activity
-
PID: 20176294
-
Rolland T, Abellan van Kan G, Vellas B (2010) Healthy brain aging: role of exercise and physical activity. Clin Geriatr Med 26(1):75–78
-
(2010)
Clin Geriatr Med
, vol.26
, Issue.1
, pp. 75-78
-
-
Rolland, T.1
Abellan van Kan, G.2
Vellas, B.3
-
181
-
-
10744232772
-
Variability of the SIRT3 gene, human silent information regulator Sir2 homologue, and survivorship in the elderly
-
COI: 1:CAS:528:DC%2BD3sXot12jsbk%3D, PID: 14580859
-
Rose G, Dato S, Altomare K, Bellizzi D, Garasto S, Greco V, Passarino G, Feraco E, Mari V, Barbi C, BonaFe M, Franceschi C, Tan Q, Boiko S, Yashin AI, De Benedictis G (2003) Variability of the SIRT3 gene, human silent information regulator Sir2 homologue, and survivorship in the elderly. Exp Gerontol 38(10):1065–1070
-
(2003)
Exp Gerontol
, vol.38
, Issue.10
, pp. 1065-1070
-
-
Rose, G.1
Dato, S.2
Altomare, K.3
Bellizzi, D.4
Garasto, S.5
Greco, V.6
Passarino, G.7
Feraco, E.8
Mari, V.9
Barbi, C.10
BonaFe, M.11
Franceschi, C.12
Tan, Q.13
Boiko, S.14
Yashin, A.I.15
De Benedictis, G.16
-
182
-
-
77949817711
-
AMPK and SIRT1: a long-standing partnership?
-
COI: 1:CAS:528:DC%2BC3cXksl2qtbo%3D, PID: 20103737
-
Ruderman NB, Xu XJ, Nelson L, Cacicedo JM, Saha AK, Lan F, Ido Y (2010) AMPK and SIRT1: a long-standing partnership? Am J Physiol Endocrinol Metab 298(4):E751–E760
-
(2010)
Am J Physiol Endocrinol Metab
, vol.298
, Issue.4
, pp. E751-E760
-
-
Ruderman, N.B.1
Xu, X.J.2
Nelson, L.3
Cacicedo, J.M.4
Saha, A.K.5
Lan, F.6
Ido, Y.7
-
183
-
-
84991755544
-
Curcumin prevents muscle damage by regulating NF-κB and Nrf2 pathways and improves performance: an in vivo model
-
PID: 27621662
-
Sahin K, Pala R, Tuzcu M, Ozdemir O, Orhan C, Sahin N, Juturu V (2016) Curcumin prevents muscle damage by regulating NF-κB and Nrf2 pathways and improves performance: an in vivo model. J Inflamm Res 9:147–154
-
(2016)
J Inflamm Res
, vol.9
, pp. 147-154
-
-
Sahin, K.1
Pala, R.2
Tuzcu, M.3
Ozdemir, O.4
Orhan, C.5
Sahin, N.6
Juturu, V.7
-
184
-
-
84855182851
-
AMP-activated protein kinase (AMPK) controls the aging process via an integrated signaling network
-
COI: 1:CAS:528:DC%2BC38Xjs1Cqtb0%3D, PID: 22186033
-
Salminen A, Kaarniranta K (2012) AMP-activated protein kinase (AMPK) controls the aging process via an integrated signaling network. Ageing Res Rev 11(2):230–241
-
(2012)
Ageing Res Rev
, vol.11
, Issue.2
, pp. 230-241
-
-
Salminen, A.1
Kaarniranta, K.2
-
185
-
-
52449083947
-
Curcumin in cell death processes: a challenge for CAM of age-related pathologies
-
COI: 1:STN:280:DC%2BC3cfgsFWrsA%3D%3D
-
Salvioli S, Sikora E, Cooper EL, Franceschi C (2007) Curcumin in cell death processes: a challenge for CAM of age-related pathologies. Evid Based Complement Altern Med 4(2):181–190
-
(2007)
Evid Based Complement Altern Med
, vol.4
, Issue.2
, pp. 181-190
-
-
Salvioli, S.1
Sikora, E.2
Cooper, E.L.3
Franceschi, C.4
-
186
-
-
34447299398
-
Role of pro-oxidants and antioxidants in the anti-inflammatory and apoptotic effects of curcumin (diferuloylmethane)
-
COI: 1:CAS:528:DC%2BD2sXotVWrsr0%3D, PID: 17640567
-
Sandur SK, Ichikawa H, Pandey MK, Kunnumakkara AB, Sung B, Sethi G, Aggarwal BB (2007) Role of pro-oxidants and antioxidants in the anti-inflammatory and apoptotic effects of curcumin (diferuloylmethane). Free Radic Biol Med 43:568–580
-
(2007)
Free Radic Biol Med
, vol.43
, pp. 568-580
-
-
Sandur, S.K.1
Ichikawa, H.2
Pandey, M.K.3
Kunnumakkara, A.B.4
Sung, B.5
Sethi, G.6
Aggarwal, B.B.7
-
187
-
-
33748331132
-
Progressive loss of SIRT1 with cell cycle withdrawal
-
COI: 1:CAS:528:DC%2BD28XhtFSisb3J, PID: 16939484
-
Sasaki T, Maier B, Bartke A, Scrable H (2006) Progressive loss of SIRT1 with cell cycle withdrawal. Aging Cell 5:413–422
-
(2006)
Aging Cell
, vol.5
, pp. 413-422
-
-
Sasaki, T.1
Maier, B.2
Bartke, A.3
Scrable, H.4
-
188
-
-
84883476818
-
Sirt1 extends life span and delays aging in mice through the regulation of Nk2 homeobox 1 in the DMH and LH
-
COI: 1:CAS:528:DC%2BC3sXhsVShtbnJ, PID: 24011076
-
Satoh A, Brace CS, Rensing N, Cliften P, Wozniak DF, Herzog ED, Yamada KA, Imai S (2013) Sirt1 extends life span and delays aging in mice through the regulation of Nk2 homeobox 1 in the DMH and LH. Cell Metab 18:416–430
-
(2013)
Cell Metab
, vol.18
, pp. 416-430
-
-
Satoh, A.1
Brace, C.S.2
Rensing, N.3
Cliften, P.4
Wozniak, D.F.5
Herzog, E.D.6
Yamada, K.A.7
Imai, S.8
-
189
-
-
13944258164
-
Chemical activation of Sir2-dependent silencing by relief of nicotinamide inhibition
-
COI: 1:CAS:528:DC%2BD2MXit12rtLs%3D, PID: 15721262
-
Sauve AA, Moir RD, Schramm VL, Willis IM (2005) Chemical activation of Sir2-dependent silencing by relief of nicotinamide inhibition. Mol Cell 17(4):595–601
-
(2005)
Mol Cell
, vol.17
, Issue.4
, pp. 595-601
-
-
Sauve, A.A.1
Moir, R.D.2
Schramm, V.L.3
Willis, I.M.4
-
190
-
-
84969872759
-
Exercise prevents diet-induced cellular senescence in adipose tissue
-
COI: 1:CAS:528:DC%2BC28XhslWns73F, PID: 26983960
-
Schafer MJ, White TA, Evans G, Tonne JM, Verzosa GC, Stout MB, Mazula DL, Palmer AK, Baker DJ, Jensen MD, Torbenson MS, Miller JD, Ikeda Y, Tchkonia T, van Deursen JM, Kirkland JL, LeBrasseur NK (2016) Exercise prevents diet-induced cellular senescence in adipose tissue. Diabetes 65(6):1606–1615
-
(2016)
Diabetes
, vol.65
, Issue.6
, pp. 1606-1615
-
-
Schafer, M.J.1
White, T.A.2
Evans, G.3
Tonne, J.M.4
Verzosa, G.C.5
Stout, M.B.6
Mazula, D.L.7
Palmer, A.K.8
Baker, D.J.9
Jensen, M.D.10
Torbenson, M.S.11
Miller, J.D.12
Ikeda, Y.13
Tchkonia, T.14
van Deursen, J.M.15
Kirkland, J.L.16
LeBrasseur, N.K.17
-
191
-
-
34247271282
-
SirT3 is a nuclear NAD+-dependent histone deacetylase that translocates to the mitochondria upon cellular stress
-
COI: 1:CAS:528:DC%2BD2sXkslKjtLk%3D, PID: 17437997
-
Scher MB, Vaquero A, Reinberg D (2007) SirT3 is a nuclear NAD+-dependent histone deacetylase that translocates to the mitochondria upon cellular stress. Genes Dev 21:920–928
-
(2007)
Genes Dev
, vol.21
, pp. 920-928
-
-
Scher, M.B.1
Vaquero, A.2
Reinberg, D.3
-
192
-
-
0037135972
-
The human silent information regulator (Sir)2 homologue hSIRT3 is a mitochondrial nicotinamide adenine dinucleotide-dependent deacetylase
-
COI: 1:CAS:528:DC%2BD38XmsVSntbk%3D, PID: 12186850
-
Schwer B, North BJ, Frye RA, Ott M, Verdin E (2002) The human silent information regulator (Sir)2 homologue hSIRT3 is a mitochondrial nicotinamide adenine dinucleotide-dependent deacetylase. J Cell Biol 158:647–657
-
(2002)
J Cell Biol
, vol.158
, pp. 647-657
-
-
Schwer, B.1
North, B.J.2
Frye, R.A.3
Ott, M.4
Verdin, E.5
-
193
-
-
1642602686
-
Senescing human cells and ageing mice accumulate DNA lesions with unrepairable doublestrand breaks
-
COI: 1:CAS:528:DC%2BD2cXosFShtA%3D%3D, PID: 14755273
-
Sedelnikova OA, Horikawa I, Zimonjic DB, Popescu NC, Bonner WM, Barrett JC (2004) Senescing human cells and ageing mice accumulate DNA lesions with unrepairable doublestrand breaks. Nat Cell Biol 6:168–170
-
(2004)
Nat Cell Biol
, vol.6
, pp. 168-170
-
-
Sedelnikova, O.A.1
Horikawa, I.2
Zimonjic, D.B.3
Popescu, N.C.4
Bonner, W.M.5
Barrett, J.C.6
-
194
-
-
84880068090
-
The role of SIRT6 protein in aging and reprogramming of human induced pluripotent stem cells
-
COI: 1:CAS:528:DC%2BC3sXpvVGlurc%3D, PID: 23653361
-
Sharma A, Diecke S, Zhang WY, Lan F, He C, Mordwinkin NM, Chua KF, Wu JC (2013) The role of SIRT6 protein in aging and reprogramming of human induced pluripotent stem cells. J Biol Chem 288:18439–18447
-
(2013)
J Biol Chem
, vol.288
, pp. 18439-18447
-
-
Sharma, A.1
Diecke, S.2
Zhang, W.Y.3
Lan, F.4
He, C.5
Mordwinkin, N.M.6
Chua, K.F.7
Wu, J.C.8
-
195
-
-
78649509214
-
SIRT3 deacetylates mitochondrial 3-hydroxy-3-methylglutaryl CoA synthase 2 and regulates ketone body production
-
COI: 1:CAS:528:DC%2BC3cXhsVyhs7jI, PID: 21109197
-
Shimazu T, Hirschey MD, Hua L, Dittenhafer-Reed KE, Schwer B, Lombard DB, Li Y, Bunkenborg J, Alt FW, Denu JM, Jacobson MP, Verdin E (2010) SIRT3 deacetylates mitochondrial 3-hydroxy-3-methylglutaryl CoA synthase 2 and regulates ketone body production. Cell Metab 12(6):654–661
-
(2010)
Cell Metab
, vol.12
, Issue.6
, pp. 654-661
-
-
Shimazu, T.1
Hirschey, M.D.2
Hua, L.3
Dittenhafer-Reed, K.E.4
Schwer, B.5
Lombard, D.B.6
Li, Y.7
Bunkenborg, J.8
Alt, F.W.9
Denu, J.M.10
Jacobson, M.P.11
Verdin, E.12
-
196
-
-
77249109022
-
The promise of slow down ageing may come from curcumin
-
COI: 1:CAS:528:DC%2BC3cXhtlCqtbfP, PID: 20388102
-
Sikora E, Bielak-Zmijewska A, Mosieniak G, Piwocka K (2010a) The promise of slow down ageing may come from curcumin. Curr Pharm Des 16(7):884–892
-
(2010)
Curr Pharm Des
, vol.16
, Issue.7
, pp. 884-892
-
-
Sikora, E.1
Bielak-Zmijewska, A.2
Mosieniak, G.3
Piwocka, K.4
-
197
-
-
77249112848
-
Curcumin, inflammation, ageing and age-related diseases
-
COI: 1:CAS:528:DC%2BC3cXht1eitbY%3D, PID: 20205886
-
Sikora E, Scapagnini G, Barbagallo M (2010b) Curcumin, inflammation, ageing and age-related diseases. Immun Ageing 7(1):1
-
(2010)
Immun Ageing
, vol.7
, Issue.1
, pp. 1
-
-
Sikora, E.1
Scapagnini, G.2
Barbagallo, M.3
-
198
-
-
0031459980
-
Extrachromosomal rDNA circles—a cause of aging in yeast
-
COI: 1:CAS:528:DyaK1cXjtVKitQ%3D%3D, PID: 9428525
-
Sinclair D, Guarente L (1997) Extrachromosomal rDNA circles—a cause of aging in yeast. Cell 91:1033–1042
-
(1997)
Cell
, vol.91
, pp. 1033-1042
-
-
Sinclair, D.1
Guarente, L.2
-
199
-
-
80054886878
-
Effects of aerobic vs. resistance training on visceral and liver fat stores, liver enzymes, and insulin resistance by HOMA in overweight adults from STRRIDE AT/RT
-
COI: 1:CAS:528:DC%2BC3MXhsFaksbnK, PID: 21846904
-
Slentz CA, Bateman LA, Willis LH, Shields AT, Tanner CJ, Piner LW, Hawk VH, Muehlbauer MJ, Samsa GP, Nelson RC, Huffman KM, Bales CW, Houmard JA, Kraus WE (2011) Effects of aerobic vs. resistance training on visceral and liver fat stores, liver enzymes, and insulin resistance by HOMA in overweight adults from STRRIDE AT/RT. Am J Physiol Endocrinol Metab 301(5):E1033–E1039
-
(2011)
Am J Physiol Endocrinol Metab
, vol.301
, Issue.5
, pp. E1033-E1039
-
-
Slentz, C.A.1
Bateman, L.A.2
Willis, L.H.3
Shields, A.T.4
Tanner, C.J.5
Piner, L.W.6
Hawk, V.H.7
Muehlbauer, M.J.8
Samsa, G.P.9
Nelson, R.C.10
Huffman, K.M.11
Bales, C.W.12
Houmard, J.A.13
Kraus, W.E.14
-
200
-
-
0036165489
-
5-Aminoimidazole-4-carboxamide ribonucleoside treatment improves glucose homeostasis in insulin-resistant diabetic (ob/ob) mice
-
COI: 1:CAS:528:DC%2BD38Xitl2js74%3D, PID: 11845224
-
Song XM, Fiedler M, Galuska D, Ryder JW, Fernstrom M, Chibalin AV, Wallberg-Henriksson H, Zierath JR (2002) 5-Aminoimidazole-4-carboxamide ribonucleoside treatment improves glucose homeostasis in insulin-resistant diabetic (ob/ob) mice. Diabetologia 45:56–65
-
(2002)
Diabetologia
, vol.45
, pp. 56-65
-
-
Song, X.M.1
Fiedler, M.2
Galuska, D.3
Ryder, J.W.4
Fernstrom, M.5
Chibalin, A.V.6
Wallberg-Henriksson, H.7
Zierath, J.R.8
-
201
-
-
61449133232
-
Currying the heart: curcumin and cardioprotection
-
COI: 1:CAS:528:DC%2BD1MXjsValtbY%3D, PID: 19153099
-
Srivastava G, Mehta JL (2009) Currying the heart: curcumin and cardioprotection. J Cardiovasc Pharmacol Ther 14(1):22–27
-
(2009)
J Cardiovasc Pharmacol Ther
, vol.14
, Issue.1
, pp. 22-27
-
-
Srivastava, G.1
Mehta, J.L.2
-
202
-
-
42149141146
-
Functionally significant insulin-like growth factor I receptor mutations in centenarians
-
COI: 1:CAS:528:DC%2BD1cXjtlKktL4%3D, PID: 18316725
-
Suh Y, Atzmon G, Cho MO, Hwang D, Liu B, Leahy DJ, Barzilai N, Cohen P (2008) Functionally significant insulin-like growth factor I receptor mutations in centenarians. Proc Natl Acad Sci USA 105:3438–3442
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 3438-3442
-
-
Suh, Y.1
Atzmon, G.2
Cho, M.O.3
Hwang, D.4
Liu, B.5
Leahy, D.J.6
Barzilai, N.7
Cohen, P.8
-
203
-
-
84901236844
-
Activation of SIRT1 by curcumin blocks the neurotoxicity of amyloid-beta25–35 in rat cortical neurons
-
COI: 1:CAS:528:DC%2BC2cXnt1GnsLg%3D, PID: 24755072
-
Sun Q, Jia N, Wang W, Jin H, Xu J, Hu H (2014) Activation of SIRT1 by curcumin blocks the neurotoxicity of amyloid-beta25–35 in rat cortical neurons. Biochem Biophys Res Commun 448:89–94
-
(2014)
Biochem Biophys Res Commun
, vol.448
, pp. 89-94
-
-
Sun, Q.1
Jia, N.2
Wang, W.3
Jin, H.4
Xu, J.5
Hu, H.6
-
204
-
-
84940947887
-
Curcumin attenuates hydrogen peroxide-induced premature senescence via the activation of SIRT1 in human umbilical vein endothelial cells
-
COI: 1:CAS:528:DC%2BC28Xis1KitLs%3D, PID: 26235577
-
Sun Y, Hu X, Hu G, Xu C, Jiang H (2015) Curcumin attenuates hydrogen peroxide-induced premature senescence via the activation of SIRT1 in human umbilical vein endothelial cells. Biol Pharm Bull 38(8):1134–1141
-
(2015)
Biol Pharm Bull
, vol.38
, Issue.8
, pp. 1134-1141
-
-
Sun, Y.1
Hu, X.2
Hu, G.3
Xu, C.4
Jiang, H.5
-
205
-
-
84877264041
-
2-induced senescence in human umbilical vein endothelial cells through SIRT1 activation
-
COI: 1:CAS:528:DC%2BC3sXovFersbk%3D, PID: 23588928
-
2-induced senescence in human umbilical vein endothelial cells through SIRT1 activation. Mol Med Rep 7:1865–1870
-
(2013)
Mol Med Rep
, vol.7
, pp. 1865-1870
-
-
Suo, R.1
Zhao, Z.Z.2
Tang, Z.H.3
Ren, Z.4
Liu, X.5
Liu, L.S.6
Wang, Z.7
Tang, C.K.8
Wei, D.H.9
Jiang, Z.S.10
-
206
-
-
0034687694
-
Silent information regulator 2 family of NAD-dependent histone/protein deacetylases generates a unique product, 1-O-acetyl-ADP-ribose
-
COI: 1:CAS:528:DC%2BD3MXitVCnsg%3D%3D, PID: 11106374
-
Tanner KG, Landty J, Sternglanz R, Denu JM (2000) Silent information regulator 2 family of NAD-dependent histone/protein deacetylases generates a unique product, 1-O-acetyl-ADP-ribose. Proc Natl Acad Sci USA 97:14178–14182
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 14178-14182
-
-
Tanner, K.G.1
Landty, J.2
Sternglanz, R.3
Denu, J.M.4
-
207
-
-
84929646351
-
Sirtuin functions in female fertility: possible role in oxidative stress and aging
-
PID: 26075037
-
Tatone C, Di Emidio G, Vitti M, Di Carlo M, Santini S Jr, D’Alessandro AM, Falone S, Amicarelli F (2015) Sirtuin functions in female fertility: possible role in oxidative stress and aging. Oxid Med Cell Longev 2015:659687
-
(2015)
Oxid Med Cell Longev
, vol.2015
, pp. 659687
-
-
Tatone, C.1
Di Emidio, G.2
Vitti, M.3
Di Carlo, M.4
Santini, S.5
D’Alessandro, A.M.6
Falone, S.7
Amicarelli, F.8
-
208
-
-
78650889400
-
Chromatin regulation and genome maintenance by mammalian SIRT6
-
COI: 1:CAS:528:DC%2BC3MXksFKgtA%3D%3D, PID: 20729089
-
Tennen RI, Chua KF (2011) Chromatin regulation and genome maintenance by mammalian SIRT6. Trends Biochem Sci 36:39–46
-
(2011)
Trends Biochem Sci
, vol.36
, pp. 39-46
-
-
Tennen, R.I.1
Chua, K.F.2
-
209
-
-
0035826271
-
Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans
-
COI: 1:CAS:528:DC%2BD3MXitVyqtbg%3D, PID: 11242085
-
Tissenbaum HA, Guarente L (2001) Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans. Nature 410(6825):227–230
-
(2001)
Nature
, vol.410
, Issue.6825
, pp. 227-230
-
-
Tissenbaum, H.A.1
Guarente, L.2
-
210
-
-
84904858835
-
Insulin-like growth factor-1 regulates the SIRT1-p53 pathway in cellular senescence
-
COI: 1:CAS:528:DC%2BC2cXht1aksr7F, PID: 25070626
-
Tran D, Bergholz J, Zhang H, He H, Wang Y, Zhang Y, Li Q, Kirkland JL, Xiao ZX (2014) Insulin-like growth factor-1 regulates the SIRT1-p53 pathway in cellular senescence. Aging Cell 13:669–678
-
(2014)
Aging Cell
, vol.13
, pp. 669-678
-
-
Tran, D.1
Bergholz, J.2
Zhang, H.3
He, H.4
Wang, Y.5
Zhang, Y.6
Li, Q.7
Kirkland, J.L.8
Xiao, Z.X.9
-
211
-
-
0033610894
-
CobB, a new member of the SIR2 family of eucaryotic regulatory proteins, is required to compensate for the lack of nicotinate mononucleotide:5,6-dimethylbenzimidazole phosphoribosyltransferase activity in cobT mutants during cobalamin biosynthesis in Salmonella typhimurium LT2
-
COI: 1:CAS:528:DyaK1cXnvVelsLk%3D, PID: 9822644
-
Tsang AW, Escalante-Semerena JC (1998) CobB, a new member of the SIR2 family of eucaryotic regulatory proteins, is required to compensate for the lack of nicotinate mononucleotide:5,6-dimethylbenzimidazole phosphoribosyltransferase activity in cobT mutants during cobalamin biosynthesis in Salmonella typhimurium LT2. J Biol Chem 273(48):31788–31794
-
(1998)
J Biol Chem
, vol.273
, Issue.48
, pp. 31788-31794
-
-
Tsang, A.W.1
Escalante-Semerena, J.C.2
-
212
-
-
33751242797
-
Sirtuin-independent effects of nicotinamide on lifespan extension from calorie restriction in yeast
-
COI: 1:CAS:528:DC%2BD2sXhsF2gtA%3D%3D, PID: 17129213
-
Tsuchiya M, Dang N, Kerr EO, Hu D, Steffen KK, Oakes JA, Kennedy BK, Kaeberlein M (2006) Sirtuin-independent effects of nicotinamide on lifespan extension from calorie restriction in yeast. Aging Cell 5:505–514
-
(2006)
Aging Cell
, vol.5
, pp. 505-514
-
-
Tsuchiya, M.1
Dang, N.2
Kerr, E.O.3
Hu, D.4
Steffen, K.K.5
Oakes, J.A.6
Kennedy, B.K.7
Kaeberlein, M.8
-
213
-
-
84923121157
-
The renoprotective effect of curcumin in cisplatin-induced nephrotoxicity
-
COI: 1:CAS:528:DC%2BC2MXjt1ags7k%3D, PID: 25594614
-
Ugur S, Ulu R, Dogukan A, Gurel A, Yigit IP, Gozel N, Aygen B, Ilhan N (2015) The renoprotective effect of curcumin in cisplatin-induced nephrotoxicity. Ren Fail 37(2):332–336
-
(2015)
Ren Fail
, vol.37
, Issue.2
, pp. 332-336
-
-
Ugur, S.1
Ulu, R.2
Dogukan, A.3
Gurel, A.4
Yigit, I.P.5
Gozel, N.6
Aygen, B.7
Ilhan, N.8
-
214
-
-
41449083867
-
Sirt7 increases stress resistance of cardiomyocytes and prevents apoptosis and inflammatory cardiomyopathy in mice
-
COI: 1:CAS:528:DC%2BD1cXjs1WmsbY%3D, PID: 18239138
-
Vakhrusheva O, Smolka C, Gajawada P, Kostin S, Boettger T, Kubin T, Braun T, Bober E (2008) Sirt7 increases stress resistance of cardiomyocytes and prevents apoptosis and inflammatory cardiomyopathy in mice. Circ Res 102(6):703–710
-
(2008)
Circ Res
, vol.102
, Issue.6
, pp. 703-710
-
-
Vakhrusheva, O.1
Smolka, C.2
Gajawada, P.3
Kostin, S.4
Boettger, T.5
Kubin, T.6
Braun, T.7
Bober, E.8
-
215
-
-
65449188292
-
Exercise and the brain: something to chew on
-
PID: 19349082
-
van Praag H (2009) Exercise and the brain: something to chew on. Trends Neurosci 32(5):283–290
-
(2009)
Trends Neurosci
, vol.32
, Issue.5
, pp. 283-290
-
-
van Praag, H.1
-
216
-
-
70349138701
-
The conserved role of sirtuins in chromatin regulation
-
COI: 1:CAS:528:DC%2BD1MXptVekur0%3D, PID: 19378253
-
Vaquero A (2009) The conserved role of sirtuins in chromatin regulation. Int J Dev Biol 53:303–322
-
(2009)
Int J Dev Biol
, vol.53
, pp. 303-322
-
-
Vaquero, A.1
-
217
-
-
33646550204
-
SirT2 is a histone deacetylase with preference for histone H4 Lys 16 during mitosis
-
COI: 1:CAS:528:DC%2BD28XltVyrtbw%3D, PID: 16648462
-
Vaquero A, Scher MB, Lee DH, Sutton A, Cheng HL, Alt FW, Serrano L, Sternglanz R, Reinberg D (2006) SirT2 is a histone deacetylase with preference for histone H4 Lys 16 during mitosis. Genes Dev 20:1256–1261
-
(2006)
Genes Dev
, vol.20
, pp. 1256-1261
-
-
Vaquero, A.1
Scher, M.B.2
Lee, D.H.3
Sutton, A.4
Cheng, H.L.5
Alt, F.W.6
Serrano, L.7
Sternglanz, R.8
Reinberg, D.9
-
218
-
-
36248954501
-
SIRT1 regulates the histone methyl-transferase SUV39H1 during heterochromatin formation
-
COI: 1:CAS:528:DC%2BD2sXhtlajs7%2FM, PID: 18004385
-
Vaquero A, Scher M, Erdjument-Bromage H, Tempst P, Serrano L, Reinberg D (2007) SIRT1 regulates the histone methyl-transferase SUV39H1 during heterochromatin formation. Nature 450(7168):440–444
-
(2007)
Nature
, vol.450
, Issue.7168
, pp. 440-444
-
-
Vaquero, A.1
Scher, M.2
Erdjument-Bromage, H.3
Tempst, P.4
Serrano, L.5
Reinberg, D.6
-
219
-
-
84897516843
-
Accelerated senescence of cord blood endothelial progenitor cells in premature neonates is driven by SIRT1 decreased expression
-
COI: 1:CAS:528:DC%2BC2cXlvFCqt7k%3D, PID: 24518759
-
Vassallo PF, Simoncini S, Ligi I, Chateau AL, Bachelier R, Robert S, Morere J, Fernandez S, Guillet B, Marcelli M, Tellier E, Pascal A, Simeoni U, Anfosso F, Magdinier F, Dignat-George F, Sabatier F (2014) Accelerated senescence of cord blood endothelial progenitor cells in premature neonates is driven by SIRT1 decreased expression. Blood 123(13):2116–2126
-
(2014)
Blood
, vol.123
, Issue.13
, pp. 2116-2126
-
-
Vassallo, P.F.1
Simoncini, S.2
Ligi, I.3
Chateau, A.L.4
Bachelier, R.5
Robert, S.6
Morere, J.7
Fernandez, S.8
Guillet, B.9
Marcelli, M.10
Tellier, E.11
Pascal, A.12
Simeoni, U.13
Anfosso, F.14
Magdinier, F.15
Dignat-George, F.16
Sabatier, F.17
-
220
-
-
84913600621
-
Canonical Wnt signaling induces vascular endothelial dysfunction via p66Shc-regulated reactive oxygen species
-
COI: 1:CAS:528:DC%2BC2cXhsFKnsLvK, PID: 25147340
-
Vikram A, Kim YR, Kumar S, Naqvi A, Hoffman TA, Kumar A, Miller FJ Jr, Kim CS, Irani K (2014) Canonical Wnt signaling induces vascular endothelial dysfunction via p66Shc-regulated reactive oxygen species. Arterioscler Thromb Vasc Biol 34(10):2301–2309
-
(2014)
Arterioscler Thromb Vasc Biol
, vol.34
, Issue.10
, pp. 2301-2309
-
-
Vikram, A.1
Kim, Y.R.2
Kumar, S.3
Naqvi, A.4
Hoffman, T.A.5
Kumar, A.6
Miller, F.J.7
Kim, C.S.8
Irani, K.9
-
221
-
-
34447626095
-
SIRT2 deacetylates FOXO3a in response to oxidative stress and caloric restriction
-
COI: 1:CAS:528:DC%2BD2sXptlyksrc%3D, PID: 17521387
-
Wang F, Nguyen M, Qin FX, Tong Q (2007) SIRT2 deacetylates FOXO3a in response to oxidative stress and caloric restriction. Aging Cell 6:505–514
-
(2007)
Aging Cell
, vol.6
, pp. 505-514
-
-
Wang, F.1
Nguyen, M.2
Qin, F.X.3
Tong, Q.4
-
222
-
-
53149137486
-
Impaired DNA damage response, genome instability, and tumorigenesis in SIRT1 mutant mice
-
COI: 1:CAS:528:DC%2BD1cXht1GlsL3F, PID: 18835033
-
Wang RH, Sengupta K, Li C, Li C, Kim HS, Cao L, Xiao C, Kim S, Xu X, Zheng Y, Chilton B, Jia R, Zheng ZM, Appella E, Wang XW, Ried T, Deng CX (2008) Impaired DNA damage response, genome instability, and tumorigenesis in SIRT1 mutant mice. Cancer Cell 14:312–323
-
(2008)
Cancer Cell
, vol.14
, pp. 312-323
-
-
Wang, R.H.1
Sengupta, K.2
Li, C.3
Li, C.4
Kim, H.S.5
Cao, L.6
Xiao, C.7
Kim, S.8
Xu, X.9
Zheng, Y.10
Chilton, B.11
Jia, R.12
Zheng, Z.M.13
Appella, E.14
Wang, X.W.15
Ried, T.16
Deng, C.X.17
-
223
-
-
79952537492
-
Nicotinamide phosphoribosyltransferase protects against ischemic stroke through SIRT1-dependent adenosine monophosphate-activated kinase pathway
-
COI: 1:CAS:528:DC%2BC3MXktl2lsLk%3D, PID: 21246601
-
Wang P, Xu TY, Guan YF, Tian WW, Viollet B, Rui YC, Zhai QW, Su DF, Miao CY (2011) Nicotinamide phosphoribosyltransferase protects against ischemic stroke through SIRT1-dependent adenosine monophosphate-activated kinase pathway. Ann Neurol 69:360–374
-
(2011)
Ann Neurol
, vol.69
, pp. 360-374
-
-
Wang, P.1
Xu, T.Y.2
Guan, Y.F.3
Tian, W.W.4
Viollet, B.5
Rui, Y.C.6
Zhai, Q.W.7
Su, D.F.8
Miao, C.Y.9
-
224
-
-
84907390733
-
P7C3 neuroprotective chemicals function by activating the rate-limiting enzyme in NAD salvage
-
COI: 1:CAS:528:DC%2BC2cXhsFCgtLjL, PID: 25215490
-
Wang G, Han T, Nijhawan D, Theodoropoulos P, Naidoo J, Yadavalli S, Mirzaei H, Pieper AA, Ready JM, McKnight SL (2014) P7C3 neuroprotective chemicals function by activating the rate-limiting enzyme in NAD salvage. Cell 158:1324–1334
-
(2014)
Cell
, vol.158
, pp. 1324-1334
-
-
Wang, G.1
Han, T.2
Nijhawan, D.3
Theodoropoulos, P.4
Naidoo, J.5
Yadavalli, S.6
Mirzaei, H.7
Pieper, A.A.8
Ready, J.M.9
McKnight, S.L.10
-
225
-
-
84959176827
-
Screening SIRT1 activators from medicinal plants as bioactive compounds against oxidative damage in mitochondrial function
-
PID: 26981165
-
Wang Y, Liang X, Chen Y, Zhao X (2016) Screening SIRT1 activators from medicinal plants as bioactive compounds against oxidative damage in mitochondrial function. Oxid Med Cell Longev 2016:4206392
-
(2016)
Oxid Med Cell Longev
, vol.2016
, pp. 4206392
-
-
Wang, Y.1
Liang, X.2
Chen, Y.3
Zhao, X.4
-
226
-
-
84960153337
-
The role of sirtuins in aging and age-related diseases
-
PID: 26521204
-
Watroba M, Szukiewicz D (2016) The role of sirtuins in aging and age-related diseases. Adv Med Sci 61:52–62
-
(2016)
Adv Med Sci
, vol.61
, pp. 52-62
-
-
Watroba, M.1
Szukiewicz, D.2
-
227
-
-
0030739927
-
Activity measures in rhesus monkeys on long-term calorie restriction
-
COI: 1:CAS:528:DyaK2sXksFGit70%3D, PID: 9226348
-
Weed JL, Lane MA, Roth GS, Speer DL, Ingram DK (1997) Activity measures in rhesus monkeys on long-term calorie restriction. Physiol Behav 62:97–103
-
(1997)
Physiol Behav
, vol.62
, pp. 97-103
-
-
Weed, J.L.1
Lane, M.A.2
Roth, G.S.3
Speer, D.L.4
Ingram, D.K.5
-
228
-
-
0030466371
-
The retardation of aging by caloric restriction: studies in rodents and primates
-
COI: 1:STN:280:DyaK2s7kslChug%3D%3D, PID: 8994305
-
Weindruch R (1996) The retardation of aging by caloric restriction: studies in rodents and primates. Toxicol Pathol 24(6):742–745
-
(1996)
Toxicol Pathol
, vol.24
, Issue.6
, pp. 742-745
-
-
Weindruch, R.1
-
229
-
-
84995694913
-
A sirtuin activator and an anti-inflammatory molecule-multifaceted roles of adjudin and its potential applications for aging-related diseases
-
COI: 1:CAS:528:DC%2BC28XhtlWns77L, PID: 27450234
-
Xia W, Geng K (2016) A sirtuin activator and an anti-inflammatory molecule-multifaceted roles of adjudin and its potential applications for aging-related diseases. Semin Cell Dev Biol 59:71–78
-
(2016)
Semin Cell Dev Biol
, vol.59
, pp. 71-78
-
-
Xia, W.1
Geng, K.2
-
230
-
-
78449248442
-
SIRT6 deficiency results in severe hypoglycemia by enhancing both basal and insulinstimulated glucose uptake in mice
-
COI: 1:CAS:528:DC%2BC3cXhsVWgsrvO, PID: 20847051
-
Xiao C, Kim HS, Lahusen T, Wang RH, Xu X, Gavrilova O, Jou W, Gius D, Deng CX (2010) SIRT6 deficiency results in severe hypoglycemia by enhancing both basal and insulinstimulated glucose uptake in mice. J Biol Chem 285(47):36776–36784
-
(2010)
J Biol Chem
, vol.285
, Issue.47
, pp. 36776-36784
-
-
Xiao, C.1
Kim, H.S.2
Lahusen, T.3
Wang, R.H.4
Xu, X.5
Gavrilova, O.6
Jou, W.7
Gius, D.8
Deng, C.X.9
-
231
-
-
79953152333
-
FoxO1 mediates an auto-feedback loop regulating SIRT1 expression
-
COI: 1:CAS:528:DC%2BC3MXhvVequ74%3D, PID: 21149440
-
Xiong S, Salazar G, Patrushev N, Alexander RW (2011) FoxO1 mediates an auto-feedback loop regulating SIRT1 expression. J Biol Chem 286:5289–5299
-
(2011)
J Biol Chem
, vol.286
, pp. 5289-5299
-
-
Xiong, S.1
Salazar, G.2
Patrushev, N.3
Alexander, R.W.4
-
232
-
-
33750445309
-
NAD metabolism and sirtuins: metabolic regulation of protein deacetylation in stress and toxicity
-
PID: 17233528
-
Yang T, Sauve AA (2006) NAD metabolism and sirtuins: metabolic regulation of protein deacetylation in stress and toxicity. AAPS J 8:E632–E643
-
(2006)
AAPS J
, vol.8
, pp. E632-E643
-
-
Yang, T.1
Sauve, A.A.2
-
233
-
-
33644828772
-
Curcumin inhibits platelet-derived growth factor-stimulated vascular smooth muscle cell function and injury-induced neointima formation
-
PID: 16239599
-
Yang X, Thomas DP, Zhang X, Culver BW, Alexander BM, Murdoch WJ, Rao MN, Tulis DA, Ren J, Sreejayan N (2006) Curcumin inhibits platelet-derived growth factor-stimulated vascular smooth muscle cell function and injury-induced neointima formation. Arterioscler Thromb Vasc Biol 26(1):85–90
-
(2006)
Arterioscler Thromb Vasc Biol
, vol.26
, Issue.1
, pp. 85-90
-
-
Yang, X.1
Thomas, D.P.2
Zhang, X.3
Culver, B.W.4
Alexander, B.M.5
Murdoch, W.J.6
Rao, M.N.7
Tulis, D.A.8
Ren, J.9
Sreejayan, N.10
-
234
-
-
84884511986
-
SIRT1 activation by curcumin pretreatment attenuates mitochondrial oxidative damage induced by myocardial ischemia reperfusion injury
-
COI: 1:CAS:528:DC%2BC3sXhvFyltL%2FN, PID: 23880291
-
Yang Y, Duan W, Lin Y, Yi W, Liang Z, Yan J, Wang N, Deng C, Zhang S, Li Y, Chen W, Yu S, Yi D, Jin Z (2013) SIRT1 activation by curcumin pretreatment attenuates mitochondrial oxidative damage induced by myocardial ischemia reperfusion injury. Free Radic Biol Med 65:667–679
-
(2013)
Free Radic Biol Med
, vol.65
, pp. 667-679
-
-
Yang, Y.1
Duan, W.2
Lin, Y.3
Yi, W.4
Liang, Z.5
Yan, J.6
Wang, N.7
Deng, C.8
Zhang, S.9
Li, Y.10
Chen, W.11
Yu, S.12
Yi, D.13
Jin, Z.14
-
235
-
-
84921847832
-
Up-regulation of nicotinamide phosphoribosyltransferase and increase of NAD+ levels by glucose restriction extend replicative lifespan of human fibroblast Hs68 cells
-
COI: 1:CAS:528:DC%2BC2cXhsVCqu77L, PID: 25146190
-
Yang N, Song T, Chang Y, Chen M, Hu M (2015) Up-regulation of nicotinamide phosphoribosyltransferase and increase of NAD+ levels by glucose restriction extend replicative lifespan of human fibroblast Hs68 cells. Biogerontology 16(1):31–42
-
(2015)
Biogerontology
, vol.16
, Issue.1
, pp. 31-42
-
-
Yang, N.1
Song, T.2
Chang, Y.3
Chen, M.4
Hu, M.5
-
236
-
-
34250897968
-
SIRT1 regulates the function of the Nijmegen breakage syndrome protein
-
COI: 1:CAS:528:DC%2BD2sXot1elsLw%3D, PID: 17612497
-
Yuan Z, Zhang X, Sengupta N, Lane WS, Seto E (2007) SIRT1 regulates the function of the Nijmegen breakage syndrome protein. Mol Cell 27:149–162
-
(2007)
Mol Cell
, vol.27
, pp. 149-162
-
-
Yuan, Z.1
Zhang, X.2
Sengupta, N.3
Lane, W.S.4
Seto, E.5
-
237
-
-
0041589716
-
Are poly(ADP-rybosyl)ation by PARP-1 and deacetylation by Sir2 linked?
-
COI: 1:CAS:528:DC%2BD3sXntVSqsLg%3D, PID: 12879452
-
Zhang J (2003) Are poly(ADP-rybosyl)ation by PARP-1 and deacetylation by Sir2 linked? BioEssays 25:808–814
-
(2003)
BioEssays
, vol.25
, pp. 808-814
-
-
Zhang, J.1
-
238
-
-
84995514584
-
SIRT1, 2, 3 protect mouse oocytes from postovulatory aging
-
PID: 26974211
-
Zhang T, Zhou Y, Li L, Wang H, Ma X, Qian W, Shen W, Schatten H, Sun Q (2016a) SIRT1, 2, 3 protect mouse oocytes from postovulatory aging. Aging 8(4):685–696
-
(2016)
Aging
, vol.8
, Issue.4
, pp. 685-696
-
-
Zhang, T.1
Zhou, Y.2
Li, L.3
Wang, H.4
Ma, X.5
Qian, W.6
Shen, W.7
Schatten, H.8
Sun, Q.9
-
239
-
-
85024882495
-
Calorie restriction-induced SIRT6 activation delays aging by suppressing NF-κB signaling
-
Zhang N, Li Z, Mu W, Li L, Liang Y, Lu M, Wang Z, Qiu Y, Wang Z (2016b) Calorie restriction-induced SIRT6 activation delays aging by suppressing NF-κB signaling. Shock 45(4):411–418
-
(2016)
Shock
, vol.45
, Issue.4
, pp. 411-418
-
-
Zhang, N.1
Li, Z.2
Mu, W.3
Li, L.4
Liang, Y.5
Lu, M.6
Wang, Z.7
Qiu, Y.8
Wang, Z.9
-
240
-
-
77954225200
-
Cytosolic FoxO1 is essential for the induction of autophagy and tumour suppressor activity
-
COI: 1:CAS:528:DC%2BC3cXot1Wmtbc%3D, PID: 20543840
-
Zhao Y, Yang J, Liao W, Liu X, Zhang H, Wang S, Wang D, Feng J, Yu L, Zhu WG (2010) Cytosolic FoxO1 is essential for the induction of autophagy and tumour suppressor activity. Nat Cell Biol 12:665–675
-
(2010)
Nat Cell Biol
, vol.12
, pp. 665-675
-
-
Zhao, Y.1
Yang, J.2
Liao, W.3
Liu, X.4
Zhang, H.5
Wang, S.6
Wang, D.7
Feng, J.8
Yu, L.9
Zhu, W.G.10
-
241
-
-
84878990866
-
Resveratrol improves learning and memory in normally aged mice through microRNA-CREB pathway
-
COI: 1:CAS:528:DC%2BC3sXptV2jtrs%3D, PID: 23685142
-
Zhao YN, Li WF, Li F, Zhang Z, Dai YD, Xu AL, Qi C, Gao JM, Gao J (2013) Resveratrol improves learning and memory in normally aged mice through microRNA-CREB pathway. Biochem Biophys Res Commun 435:597–602
-
(2013)
Biochem Biophys Res Commun
, vol.435
, pp. 597-602
-
-
Zhao, Y.N.1
Li, W.F.2
Li, F.3
Zhang, Z.4
Dai, Y.D.5
Xu, A.L.6
Qi, C.7
Gao, J.M.8
Gao, J.9
-
242
-
-
84903472690
-
Hydrogen sulfide delays nicotinamide-induced premature senescence via upregulation of SIRT1 in human umbilical vein endothelial cells
-
COI: 1:CAS:528:DC%2BC2cXmsVCntLo%3D, PID: 24729176
-
Zheng M, Qiao W, Cui J, Liu L, Liu H, Wang Z, Yan C (2014) Hydrogen sulfide delays nicotinamide-induced premature senescence via upregulation of SIRT1 in human umbilical vein endothelial cells. Mol Cell Biochem 393:59–67
-
(2014)
Mol Cell Biochem
, vol.393
, pp. 59-67
-
-
Zheng, M.1
Qiao, W.2
Cui, J.3
Liu, L.4
Liu, H.5
Wang, Z.6
Yan, C.7
-
243
-
-
74549142287
-
The histone deacetylase Sirt6 regulates glucose homeostasis via Hif1alpha
-
COI: 1:CAS:528:DC%2BC3cXkvVWitLc%3D, PID: 20141841
-
Zhong L, D’Urso A, Toiber D, Sebastian C, Henry RE, Vadysirisack DD, Guimaraes A, Marinelli B, Wikstrom JD, Nir T, Clish CB, Vaitheesvaran B, Iliopoulos O, Kurland I, Dor Y, Weissleder R, Shirihai OS, Ellisen LW, Espinosa JM, Mostoslavsky R (2010) The histone deacetylase Sirt6 regulates glucose homeostasis via Hif1alpha. Cell 140(2):280–293
-
(2010)
Cell
, vol.140
, Issue.2
, pp. 280-293
-
-
Zhong, L.1
D’Urso, A.2
Toiber, D.3
Sebastian, C.4
Henry, R.E.5
Vadysirisack, D.D.6
Guimaraes, A.7
Marinelli, B.8
Wikstrom, J.D.9
Nir, T.10
Clish, C.B.11
Vaitheesvaran, B.12
Iliopoulos, O.13
Kurland, I.14
Dor, Y.15
Weissleder, R.16
Shirihai, O.S.17
Ellisen, L.W.18
Espinosa, J.M.19
Mostoslavsky, R.20
more..
-
244
-
-
80052580047
-
Repression of P66Shc expression by SIRT1 contributes to the prevention of hyperglycemia-induced endothelial dysfunction
-
COI: 1:CAS:528:DC%2BC3MXhtFWkt7zM, PID: 21778425
-
Zhou S, Chen HZ, Wan YZ, Zhang QJ, Wei YS, Huang S, Liu JJ, Lu YB, Zhang ZQ, Yang RF, Zhang R, Cai H, Liu DP, Liang CC (2011) Repression of P66Shc expression by SIRT1 contributes to the prevention of hyperglycemia-induced endothelial dysfunction. Circ Res 109(6):639–648
-
(2011)
Circ Res
, vol.109
, Issue.6
, pp. 639-648
-
-
Zhou, S.1
Chen, H.Z.2
Wan, Y.Z.3
Zhang, Q.J.4
Wei, Y.S.5
Huang, S.6
Liu, J.J.7
Lu, Y.B.8
Zhang, Z.Q.9
Yang, R.F.10
Zhang, R.11
Cai, H.12
Liu, D.P.13
Liang, C.C.14
-
245
-
-
85007565940
-
Curcumin suppresses epithelial-mesenchymal transition of renal tubular epithelial cells through the inhibition of Akt/mTOR pathway
-
PID: 27829579
-
Zhu FQ, Chen MJ, Zhu M, Zhao RS, Qiu W, Xu X, Liu H, Zhao HW, Yu RJ, Wu XF, Zhang K, Huang H (2016) Curcumin suppresses epithelial-mesenchymal transition of renal tubular epithelial cells through the inhibition of Akt/mTOR pathway. Biol Pharm Bull 40(1):17–24
-
(2016)
Biol Pharm Bull
, vol.40
, Issue.1
, pp. 17-24
-
-
Zhu, F.Q.1
Chen, M.J.2
Zhu, M.3
Zhao, R.S.4
Qiu, W.5
Xu, X.6
Liu, H.7
Zhao, H.W.8
Yu, R.J.9
Wu, X.F.10
Zhang, K.11
Huang, H.12
|