Curcumin induces oxidation-dependent cell cycle arrest mediated by SIRT7 inhibition of rDNA transcription in human aortic smooth muscle cells

Toxicology Letters

Volumn 233, Issue 3, 2015, Pages 227-238

  Lewinska, Anna ^a   Wnuk, Maciej ^a   Grabowska, Wioleta ^b   Zabek, Tomasz ^c   Semik, Ewelina ^c   Sikora, Ewa ^b   Bielak Zmijewska, Anna ^b  

^a UNIVERSITY OF RZESZÓW   (Poland)

^b NENCKI INSTITUTE OF EXPERIMENTAL BIOLOGY   (Poland)

^c NATIONAL RESEARCH INSTITUTE OF ANIMAL PRODUCTION   (Poland)

Author keywords

Curcumin; DNMT2; Nucleolus; RDNA; SIRT7; VSMCs

Indexed keywords

CURCUMIN; DNA METHYLTRANSFERASE; DNA METHYLTRANSFERASE 2; PROTEIN P21; PROTEIN P53; RIBOSOME DNA; SIRTUIN 7; UNCLASSIFIED DRUG; DNA (CYTOSINE 5) METHYLTRANSFERASE; PROTEIN; SIRT7 PROTEIN, HUMAN; SIRTUIN; TRDMT1 PROTEIN, HUMAN;

ARTICLE; CELL CYCLE ARREST; CONTROLLED STUDY; DNA DAMAGE; DNA TRANSCRIPTION; DOWN REGULATION; ENZYME INHIBITION; HUMAN; MALE; OXIDATION; OXIDATIVE STRESS; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN CARBONYLATION; PROTEIN METHYLATION; RNA METHYLATION; RNA STABILITY; SMOOTH MUSCLE FIBER; UPREGULATION; VASCULAR SMOOTH MUSCLE; AORTA; CELL CULTURE; CELL CYCLE CHECKPOINT; CYTOLOGY; DNA METHYLATION; DRUG EFFECTS; GENETIC TRANSCRIPTION; GENETICS; METABOLISM; NUCLEOLUS; OXIDATION REDUCTION REACTION; PHYSIOLOGY;

AORTA; CELL CYCLE CHECKPOINTS; CELL NUCLEOLUS; CELLS, CULTURED; CURCUMIN; DNA (CYTOSINE-5-)-METHYLTRANSFERASE; DNA METHYLATION; DNA, RIBOSOMAL; HUMANS; MALE; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; OXIDATION-REDUCTION; PROMOTER REGIONS, GENETIC; PROTEINS; SIRTUINS; TRANSCRIPTION, GENETIC;

EID: 84922355140     PISSN: 03784274     EISSN: 18793169     Source Type: Journal    
DOI: 10.1016/j.toxlet.2015.01.019     Document Type: Article

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