Paeonol protects against premature senescence in endothelial cells by modulating Sirtuin 1 pathway

Journal of Ethnopharmacology

Volumn 154, Issue 2, 2014, Pages 428-436

  Jamal, Juliana ^a   Mustafa, Mohd Rais ^a   Wong, Pooi Fong ^a  

^a UNIVERSITY OF MALAYA   (Malaysia)

Author keywords

Aging; Endothelial cells; Oxidative stress; Paeonol; Sirt1; Traditional Chinese medicine

Indexed keywords

ACETYL HISTONE H3 LYSINE 14; BROXURIDINE; CYTOPROTECTIVE AGENT; HISTONE H3; HISTONE H4; HISTONE H4 LYSINE 16; HYDROGEN PEROXIDE; PEONOL; PROTEIN P53; SIRTUIN 1; UNCLASSIFIED DRUG; ACETOPHENONE DERIVATIVE; REACTIVE OXYGEN METABOLITE; SIRT1 PROTEIN, HUMAN;

ARTICLE; CELL AGING; CELL GROWTH; CELL PROLIFERATION; CELL PROTECTION; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYMATIC ASSAY; ENZYME ACTIVITY; G1 PHASE CELL CYCLE CHECKPOINT; G2 PHASE CELL CYCLE CHECKPOINT; HUMAN; HUMAN CELL; OXIDATIVE STRESS; PROTEIN EXPRESSION; S PHASE CELL CYCLE CHECKPOINT; UMBILICAL VEIN ENDOTHELIAL CELL; CELL SURVIVAL; CHEMICAL STRUCTURE; CULTURE TECHNIQUE; DRUG EFFECTS; ETHNOPHARMACOLOGY; ISOLATION AND PURIFICATION; METABOLISM; SIGNAL TRANSDUCTION;

PAEONIA LACTIFLORA;

ACETOPHENONES; CELL AGING; CELL CULTURE TECHNIQUES; CELL SURVIVAL; ENDOTHELIAL CELLS; ETHNOPHARMACOLOGY; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; MOLECULAR STRUCTURE; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; SIRTUIN 1;

EID: 84901622078     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2014.04.025     Document Type: Article

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