메뉴 건너뛰기




Volumn 47, Issue 1, 2012, Pages 23-28

Effects of treadmill exercise and training frequency on anabolic signaling pathways in the skeletal muscle of aged rats

Author keywords

Aging; Insulin; Mitochondria; MTOR; Physical activity; Sarcomere volume; Sarcopenia

Indexed keywords

CYTOCHROME C OXIDASE; GLUCOSE TRANSPORTER 4; INSULIN RECEPTOR; INSULIN RECEPTOR SUBSTRATE 1; MAMMALIAN TARGET OF RAPAMYCIN;

EID: 84155163883     PISSN: 05315565     EISSN: 18736815     Source Type: Journal    
DOI: 10.1016/j.exger.2011.10.003     Document Type: Article
Times cited : (43)

References (34)
  • 1
    • 0034996561 scopus 로고    scopus 로고
    • Age effect on transcript levels and synthesis rate of muscle MHC and response to resistance exercise
    • Balagopal P., Schimke J.C., Ades P., Adey D., Nair K.S. Age effect on transcript levels and synthesis rate of muscle MHC and response to resistance exercise. Am. J. Physiol. Endocrinol. Metab. 2001, 280:E203-E208.
    • (2001) Am. J. Physiol. Endocrinol. Metab. , vol.280
    • Balagopal, P.1    Schimke, J.C.2    Ades, P.3    Adey, D.4    Nair, K.S.5
  • 2
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford M.M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 1976, 72:248-254.
    • (1976) Anal. Biochem. , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 3
    • 0030066985 scopus 로고    scopus 로고
    • Effect of aging on insulin receptor, insulin receptor substrate-1, and phosphatidylinositol 3-kinase in liver and muscle of rats
    • Carvalho C.R., Brenelli S.L., Silva A.C., Nunes A.L., Velloso L.A., Saad M.J. Effect of aging on insulin receptor, insulin receptor substrate-1, and phosphatidylinositol 3-kinase in liver and muscle of rats. Endocrinology 1996, 137:151-159.
    • (1996) Endocrinology , vol.137 , pp. 151-159
    • Carvalho, C.R.1    Brenelli, S.L.2    Silva, A.C.3    Nunes, A.L.4    Velloso, L.A.5    Saad, M.J.6
  • 5
    • 0031790471 scopus 로고    scopus 로고
    • Ultrastructural study of the alterations in spinal ganglion cells of rats chronically fed on ethanol
    • Corsetti G., Rezzani R., Rodella L., Bianchi R. Ultrastructural study of the alterations in spinal ganglion cells of rats chronically fed on ethanol. Ultrastruct. Pathol. 1998, 22:309-319.
    • (1998) Ultrastruct. Pathol. , vol.22 , pp. 309-319
    • Corsetti, G.1    Rezzani, R.2    Rodella, L.3    Bianchi, R.4
  • 7
    • 36749081539 scopus 로고    scopus 로고
    • MTOR controls mitochondrial oxidative function through a YY1-PGC-1alpha transcriptional complex
    • Cunningham J.T., Rodgers J.T., Arlow D.H., Vazquez F., Mootha V.K., Puigserver P. mTOR controls mitochondrial oxidative function through a YY1-PGC-1alpha transcriptional complex. Nature 2007, 450:736-740.
    • (2007) Nature , vol.450 , pp. 736-740
    • Cunningham, J.T.1    Rodgers, J.T.2    Arlow, D.H.3    Vazquez, F.4    Mootha, V.K.5    Puigserver, P.6
  • 8
    • 44449165370 scopus 로고    scopus 로고
    • Intracellular mechanisms of metabolism regulation: the role of signaling via the mammalian target of rapamycin pathway and other routes
    • Flati V., Pasini E., D'Antona G., Speca S., Toniato E., Martinotti S. Intracellular mechanisms of metabolism regulation: the role of signaling via the mammalian target of rapamycin pathway and other routes. Am. J. Cardiol. 2008, 101:16E-21E.
    • (2008) Am. J. Cardiol. , vol.101
    • Flati, V.1    Pasini, E.2    D'Antona, G.3    Speca, S.4    Toniato, E.5    Martinotti, S.6
  • 9
    • 34249678700 scopus 로고    scopus 로고
    • Aerobic exercise overcomes the age-related insulin resistance of muscle protein metabolism by improving endothelial function and Akt/mammalian target of rapamycin signaling
    • Fujita S., Rasmussen B.B., Cadenas J.G., Drummond M.J., Glynn E.L., Sattler F.R., Volpi E. Aerobic exercise overcomes the age-related insulin resistance of muscle protein metabolism by improving endothelial function and Akt/mammalian target of rapamycin signaling. Diabetes 2007, 56:1615-1622.
    • (2007) Diabetes , vol.56 , pp. 1615-1622
    • Fujita, S.1    Rasmussen, B.B.2    Cadenas, J.G.3    Drummond, M.J.4    Glynn, E.L.5    Sattler, F.R.6    Volpi, E.7
  • 10
    • 0026297978 scopus 로고
    • Endogenous cytochrome c and cytochrome oxidase in rat and mouse kidney: light microscopic histochemical study
    • Furgal A., Litwin J.A. Endogenous cytochrome c and cytochrome oxidase in rat and mouse kidney: light microscopic histochemical study. Folia Histochem. Cytobiol. 1991, 29:25-29.
    • (1991) Folia Histochem. Cytobiol. , vol.29 , pp. 25-29
    • Furgal, A.1    Litwin, J.A.2
  • 11
    • 9444290436 scopus 로고    scopus 로고
    • Impaired anabolic response of muscle protein synthesis is associated with S6K1 dysregulation in elderly humans
    • Guillet C., Prod'homme M., Balage M., Gachon P., Giraudet C., Morin L., Grizard J., Boirie Y. Impaired anabolic response of muscle protein synthesis is associated with S6K1 dysregulation in elderly humans. FASEB J. 2004, 18:1586-1587.
    • (2004) FASEB J. , vol.18 , pp. 1586-1587
    • Guillet, C.1    Prod'homme, M.2    Balage, M.3    Gachon, P.4    Giraudet, C.5    Morin, L.6    Grizard, J.7    Boirie, Y.8
  • 12
    • 0038810035 scopus 로고    scopus 로고
    • An autoregulatory loop controls peroxisome proliferator-activated receptor gamma coactivator 1alpha expression in muscle
    • Handschin C., Rhee J., Lin J., Tarr P.T., Spiegelman B.M. An autoregulatory loop controls peroxisome proliferator-activated receptor gamma coactivator 1alpha expression in muscle. Proc. Natl. Acad. Sci. U. S. A. 2003, 100:7111-7116.
    • (2003) Proc. Natl. Acad. Sci. U. S. A. , vol.100 , pp. 7111-7116
    • Handschin, C.1    Rhee, J.2    Lin, J.3    Tarr, P.T.4    Spiegelman, B.M.5
  • 15
    • 0035044213 scopus 로고    scopus 로고
    • Clinical review 125: the insulin receptor and its cellular targets
    • Kido Y., Nakae J., Accili D. Clinical review 125: the insulin receptor and its cellular targets. J. Clin. Endocrinol. Metab. 2001, 86:972-979.
    • (2001) J. Clin. Endocrinol. Metab. , vol.86 , pp. 972-979
    • Kido, Y.1    Nakae, J.2    Accili, D.3
  • 16
    • 58149389257 scopus 로고    scopus 로고
    • Muscle mitochondrial changes with aging and exercise
    • Lanza I.R., Nair K.S. Muscle mitochondrial changes with aging and exercise. Am. J. Clin. Nutr. 2009, 89:467S-471S.
    • (2009) Am. J. Clin. Nutr. , vol.89
    • Lanza, I.R.1    Nair, K.S.2
  • 18
    • 60549115947 scopus 로고    scopus 로고
    • Changes in IL-15 expression and death-receptor apoptotic signaling in rat gastrocnemius muscle with aging and life-long calorie restriction
    • Marzetti E., Carter C.S., Wohlgemuth S.E., Lees H.A., Giovannini S., Anderson B., Quinn L.S., Leeuwenburgh C. Changes in IL-15 expression and death-receptor apoptotic signaling in rat gastrocnemius muscle with aging and life-long calorie restriction. Mech. Ageing Dev. 2009, 130:272-280.
    • (2009) Mech. Ageing Dev. , vol.130 , pp. 272-280
    • Marzetti, E.1    Carter, C.S.2    Wohlgemuth, S.E.3    Lees, H.A.4    Giovannini, S.5    Anderson, B.6    Quinn, L.S.7    Leeuwenburgh, C.8
  • 22
    • 0027316018 scopus 로고
    • Physical training reverses defect in mitochondrial energy production in heart of chronically diabetic rats
    • Mokhtar N., Lavoie J.P., Rousseau-Migneron S., Nadeau A. Physical training reverses defect in mitochondrial energy production in heart of chronically diabetic rats. Diabetes 1993, 42:682-687.
    • (1993) Diabetes , vol.42 , pp. 682-687
    • Mokhtar, N.1    Lavoie, J.P.2    Rousseau-Migneron, S.3    Nadeau, A.4
  • 27
    • 0035743103 scopus 로고    scopus 로고
    • Does methylene blue protect the kidney tissues from damage induced by ciclosporin A treatment?
    • Rezzani R., Rodella L., Corsetti G., Bianchi R. Does methylene blue protect the kidney tissues from damage induced by ciclosporin A treatment?. Nephron 2001, 89:329-336.
    • (2001) Nephron , vol.89 , pp. 329-336
    • Rezzani, R.1    Rodella, L.2    Corsetti, G.3    Bianchi, R.4
  • 29
    • 0033821616 scopus 로고    scopus 로고
    • Sarcopenia: a major modifiable cause of frailty in the elderly
    • Roubenoff R. Sarcopenia: a major modifiable cause of frailty in the elderly. J. Nutr. Health Aging 2000, 4:140-142.
    • (2000) J. Nutr. Health Aging , vol.4 , pp. 140-142
    • Roubenoff, R.1
  • 30
    • 0033678865 scopus 로고    scopus 로고
    • Insulin resistance with aging: effects of diet and exercise
    • Ryan A.S. Insulin resistance with aging: effects of diet and exercise. Sports Med. 2000, 30:327-346.
    • (2000) Sports Med. , vol.30 , pp. 327-346
    • Ryan, A.S.1
  • 31
    • 49049083353 scopus 로고    scopus 로고
    • Signaling in muscle atrophy and hypertrophy
    • Sandri M. Signaling in muscle atrophy and hypertrophy. Physiology (Bethesda) 2008, 23:160-170.
    • (2008) Physiology (Bethesda) , vol.23 , pp. 160-170
    • Sandri, M.1
  • 32
    • 25444533562 scopus 로고    scopus 로고
    • Skeletal muscle fibres synthesis in heart failure: role of PGC-1alpha, calcineurin and GH
    • Vescovo G., Ravara B., Gobbo V., Angelini A., Dalla L.L. Skeletal muscle fibres synthesis in heart failure: role of PGC-1alpha, calcineurin and GH. Int. J. Cardiol. 2005, 104:298-306.
    • (2005) Int. J. Cardiol. , vol.104 , pp. 298-306
    • Vescovo, G.1    Ravara, B.2    Gobbo, V.3    Angelini, A.4    Dalla, L.L.5
  • 34
    • 78650510609 scopus 로고    scopus 로고
    • MTOR: from growth signal integration to cancer, diabetes and ageing
    • Zoncu R., Efeyan A., Sabatini D.M. mTOR: from growth signal integration to cancer, diabetes and ageing. Nat. Rev. Mol. Cell Biol. 2011, 12:21-35.
    • (2011) Nat. Rev. Mol. Cell Biol. , vol.12 , pp. 21-35
    • Zoncu, R.1    Efeyan, A.2    Sabatini, D.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.