Deletion of the life span determinant p66Shc prevents age-dependent increases in emotionality and pain sensitivity in mice

Experimental Gerontology

Volumn 42, Issue 1-2, 2007, Pages 37-45

  Berry, Alessandra ^a,c   Capone, Francesca ^a   Giorgio, Marco ^b   Pelicci, Pier Giuseppe ^b   de Kloet, E R ^c   Alleva, Enrico ^a   Minghetti, Luisa ^a   Cirulli, Francesca ^a  

^a ISTITUTO SUPERIORE DI SANITÀ   (Italy)

^b EUROPEAN INSTITUTE OF ONCOLOGY   (Italy)

^c LEIDEN UNIVERSITY   (Netherlands)

Author keywords

Ageing; Anxiety; Mice; Oxidative stress; P66shc; Pain sensitivity; Social behavior; Transgene

Indexed keywords

PROTEIN P66;

AGING; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; EMOTIONAL STRESS; EMOTIONALITY; EXPERIMENTAL TEST; EXPLORATORY BEHAVIOR; GENE DELETION; HOMOZYGOTE; HOT PLATE TEST; KNOCKOUT MOUSE; LIFESPAN; LOCOMOTION; MALE; MAZE TEST; MOUSE; MOUSE STRAIN; NOCICEPTION; NONHUMAN; OPEN FIELD TEST; OXIDATIVE STRESS; PAIN; PAIN THRESHOLD; PRIORITY JOURNAL; SOCIAL BEHAVIOR; WILD TYPE;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; AGING; ANIMALS; BEHAVIOR, ANIMAL; EMOTIONS; LONGEVITY; MALE; MICE; MICE, INBRED STRAINS; MICE, KNOCKOUT; MODELS, ANIMAL; PAIN; PAIN THRESHOLD;

EID: 33845571064     PISSN: 05315565     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.exger.2006.05.018     Document Type: Article

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