-
1
-
-
0001644020
-
The human plasma proteome: history, character, and diagnostic prospects
-
Anderson NL, Anderson NG (2002) The human plasma proteome: history, character, and diagnostic prospects. Mol. Cell. Proteomics 1, 845-867.
-
(2002)
Mol. Cell. Proteomics
, vol.1
, pp. 845-867
-
-
Anderson, N.L.1
Anderson, N.G.2
-
2
-
-
0036399760
-
Sarcopenia, weight loss, and nutritional frailty in the elderly
-
Bales CW, Ritchie CS (2002) Sarcopenia, weight loss, and nutritional frailty in the elderly. Annu. Rev. Nutr. 22, 309-323.
-
(2002)
Annu. Rev. Nutr.
, vol.22
, pp. 309-323
-
-
Bales, C.W.1
Ritchie, C.S.2
-
3
-
-
33645991485
-
Lower plasma vitamin E levels are associated with the frailty syndrome: the InCHIANTI study
-
Ble A, Cherubini A, Volpato S, Bartali B, Walston JD, Windham BG, Bandinelli S, Lauretani F, Guralnik JM, Ferrucci L (2006) Lower plasma vitamin E levels are associated with the frailty syndrome: the InCHIANTI study. J. Gerontol. A Biol. Sci. Med. Sci. 61, 278-283.
-
(2006)
J. Gerontol. A Biol. Sci. Med. Sci.
, vol.61
, pp. 278-283
-
-
Ble, A.1
Cherubini, A.2
Volpato, S.3
Bartali, B.4
Walston, J.D.5
Windham, B.G.6
Bandinelli, S.7
Lauretani, F.8
Guralnik, J.M.9
Ferrucci, L.10
-
4
-
-
0027202741
-
The physics of frailty
-
Bortz WM (1993) The physics of frailty. J. Am. Geriatr. Soc. 41, 1004-1008.
-
(1993)
J. Am. Geriatr. Soc.
, vol.41
, pp. 1004-1008
-
-
Bortz, W.M.1
-
5
-
-
84874422422
-
Frailty in elderly people
-
Clegg A, Young J, Iliffe S, Rikkert MO, Rockwood K (2013) Frailty in elderly people. Lancet 381, 752-762.
-
(2013)
Lancet
, vol.381
, pp. 752-762
-
-
Clegg, A.1
Young, J.2
Iliffe, S.3
Rikkert, M.O.4
Rockwood, K.5
-
6
-
-
2442699834
-
Frailty in older adults: evidence for a phenotype
-
Fried LP, Tangen CM, Walston J, Newman AB, Hirsch C, Gottdiener J, Seeman T, Tracy R, Kop WJ, Burke G, McBurnie MA (2001) Frailty in older adults: evidence for a phenotype. J. Gerontol. A Biol. Sci. Med. Sci. 56, 146-156.
-
(2001)
J. Gerontol. A Biol. Sci. Med. Sci.
, vol.56
, pp. 146-156
-
-
Fried, L.P.1
Tangen, C.M.2
Walston, J.3
Newman, A.B.4
Hirsch, C.5
Gottdiener, J.6
Seeman, T.7
Tracy, R.8
Kop, W.J.9
Burke, G.10
McBurnie, M.A.11
-
7
-
-
79958206937
-
Sirtuins, aging, and medicine
-
Guarente L (2014) Sirtuins, aging, and medicine. N. Engl. J. Med. 364, 2235-2244.
-
(2014)
N. Engl. J. Med.
, vol.364
, pp. 2235-2244
-
-
Guarente, L.1
-
8
-
-
33751113602
-
Mammalian sirtuins-emerging roles in physiology, aging, and calorie restriction
-
Haigis MC, Guarente LP (2006) Mammalian sirtuins-emerging roles in physiology, aging, and calorie restriction. Genes Dev. 20, 2913-2921.
-
(2006)
Genes Dev.
, vol.20
, pp. 2913-2921
-
-
Haigis, M.C.1
Guarente, L.P.2
-
9
-
-
77950206605
-
Ageing
-
Heemels MT (2010) Ageing. Nature 464, 503.
-
(2010)
Nature
, vol.464
, pp. 503
-
-
Heemels, M.T.1
-
10
-
-
78650758398
-
Sirt1 improves healthy ageing and protects from metabolic syndrome-associated cancer
-
Herranz D, Muñoz-Martin M, Cañamero M, Mulero F, Martinez-Pastor B, Fernandez-Capetillo O, Serrano M (2010) Sirt1 improves healthy ageing and protects from metabolic syndrome-associated cancer. Nat. Commun. 1, 3.
-
(2010)
Nat. Commun.
, vol.1
, pp. 3
-
-
Herranz, D.1
Muñoz-Martin, M.2
Cañamero, M.3
Mulero, F.4
Martinez-Pastor, B.5
Fernandez-Capetillo, O.6
Serrano, M.7
-
11
-
-
84882304814
-
Associations between frailty and serum 25-Hydroxyvitamin D and 1,25-Dihydroxyvitamin D concentrations in older Australian Men: the concord health and ageing in men project
-
Hirani V, Naganathan V, Cumming RG, Blyth F, Le Couteur DG, Handelsman DJ, Waite LM, Seibel MJ (2013) Associations between frailty and serum 25-Hydroxyvitamin D and 1, 25-Dihydroxyvitamin D concentrations in older Australian Men: the concord health and ageing in men project. J. Gerontol. A Biol. Sci. Med. Sci. 68, 1112-1121.
-
(2013)
J. Gerontol. A Biol. Sci. Med. Sci.
, vol.68
, pp. 1112-1121
-
-
Hirani, V.1
Naganathan, V.2
Cumming, R.G.3
Blyth, F.4
Le Couteur, D.G.5
Handelsman, D.J.6
Waite, L.M.7
Seibel, M.J.8
-
12
-
-
0034677535
-
Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase
-
Imai S, Armstrong CM, Kaeberlein M, Guarente L (2000) Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase. Nature 403, 795-800.
-
(2000)
Nature
, vol.403
, pp. 795-800
-
-
Imai, S.1
Armstrong, C.M.2
Kaeberlein, M.3
Guarente, L.4
-
13
-
-
0033214237
-
The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms
-
Kaeberlein M, McVey M, Guarente L (1999) The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms. Genes Dev. 13, 2570-2580.
-
(1999)
Genes Dev.
, vol.13
, pp. 2570-2580
-
-
Kaeberlein, M.1
McVey, M.2
Guarente, L.3
-
14
-
-
84876185003
-
Sirtuin1: a promising serum protein marker for early detection of Alzheimer's disease
-
Kumar R, Chaterjee P, Sharma PK, Singh AK, Gupta A, Gill K, Tripathi M, Dey AB, Dey S (2013) Sirtuin1: a promising serum protein marker for early detection of Alzheimer's disease. PLoS One 8, e61560.
-
(2013)
PLoS One
, vol.8
, pp. e61560
-
-
Kumar, R.1
Chaterjee, P.2
Sharma, P.K.3
Singh, A.K.4
Gupta, A.5
Gill, K.6
Tripathi, M.7
Dey, A.B.8
Dey, S.9
-
15
-
-
77950834672
-
SIRT1, a calorie restriction mimetic, in a new therapeutic approach for type 2 diabetes mellitus and diabetic vascular complications
-
Kume S, Uzu T, Kashiwagi A, Koya D (2010) SIRT1, a calorie restriction mimetic, in a new therapeutic approach for type 2 diabetes mellitus and diabetic vascular complications. Endocr. Metab. Immune Disord. Drug Targets 10, 16-24.
-
(2010)
Endocr. Metab. Immune Disord. Drug Targets
, vol.10
, pp. 16-24
-
-
Kume, S.1
Uzu, T.2
Kashiwagi, A.3
Koya, D.4
-
16
-
-
79951594220
-
Determinants of serum-induced SIRT1 expression in older men: the CHAMP study.J Gerontol A BiolSci
-
Le Couteur DG, Benson VL, McMahon AC, Blyth F, Handelsman DJ, Seibel MJ, Kennerson M, Naganathan V, Cumming RG, de Cabo R (2011) Determinants of serum-induced SIRT1 expression in older men: the CHAMP study.J Gerontol A BiolSci. Med. Sci. 66, 3-8.
-
(2011)
Med. Sci.
, vol.66
, pp. 3-8
-
-
Le Couteur, D.G.1
Benson, V.L.2
McMahon, A.C.3
Blyth, F.4
Handelsman, D.J.5
Seibel, M.J.6
Kennerson, M.7
Naganathan, V.8
Cumming, R.G.9
de Cabo, R.10
-
17
-
-
0036068710
-
Serum interleukin-6 and hemoglobin as physiological correlates in the geriatric syndrome of frailty: a pilot study
-
Leng S, Chaves P, Koenig K, Walston J (2002) Serum interleukin-6 and hemoglobin as physiological correlates in the geriatric syndrome of frailty: a pilot study. J. Am. Geriatr. Soc. 50, 1268-1271.
-
(2002)
J. Am. Geriatr. Soc.
, vol.50
, pp. 1268-1271
-
-
Leng, S.1
Chaves, P.2
Koenig, K.3
Walston, J.4
-
18
-
-
2642541669
-
Serum levels of insulin-like growth factor-I (IGF-I) and dehydroepiandrosterone sulfate (DHEA-S), and their relationships with serum interleukin-6, in the geriatric syndrome of frailty
-
Leng SX, Cappola AR, Andersen RE, Blackman MR, Koenig K, Blair M, Walston JD (2004) Serum levels of insulin-like growth factor-I (IGF-I) and dehydroepiandrosterone sulfate (DHEA-S), and their relationships with serum interleukin-6, in the geriatric syndrome of frailty. Aging Clin. Exp. Res. 16, 153-157.
-
(2004)
Aging Clin. Exp. Res.
, vol.16
, pp. 153-157
-
-
Leng, S.X.1
Cappola, A.R.2
Andersen, R.E.3
Blackman, M.R.4
Koenig, K.5
Blair, M.6
Walston, J.D.7
-
19
-
-
34347338725
-
Inflammation and frailty in older women
-
Leng SX, Xue QL, Tian J, Walston JD, Fried LP (2007) Inflammation and frailty in older women. J. Am. Geriatr. Soc. 55, 864-871.
-
(2007)
J. Am. Geriatr. Soc.
, vol.55
, pp. 864-871
-
-
Leng, S.X.1
Xue, Q.L.2
Tian, J.3
Walston, J.D.4
Fried, L.P.5
-
20
-
-
67650594923
-
Association of neutrophil and monocyte counts with fraily in community-dwelling older women
-
Leng S, Xue Q, Tian J (2009) Association of neutrophil and monocyte counts with fraily in community-dwelling older women. Exp. Gerontol. 44, 511-516.
-
(2009)
Exp. Gerontol.
, vol.44
, pp. 511-516
-
-
Leng, S.1
Xue, Q.2
Tian, J.3
-
21
-
-
34948883324
-
SIRT1 deacetylates and positively regulates the nuclear receptor LXR
-
Li X, Zhang S, Blander G, Tse JG, Krieger M, Guarente L (2007) SIRT1 deacetylates and positively regulates the nuclear receptor LXR. Mol. Cell 28, 91-106.
-
(2007)
Mol. Cell
, vol.28
, pp. 91-106
-
-
Li, X.1
Zhang, S.2
Blander, G.3
Tse, J.G.4
Krieger, M.5
Guarente, L.6
-
22
-
-
0026534404
-
Loss of 'complexity' and aging. Potential applications of fractals and chaos theory to senescence
-
Lipsitz LA, Goldberger AL (1992) Loss of 'complexity' and aging. Potential applications of fractals and chaos theory to senescence. JAMA 267, 1806-1809.
-
(1992)
JAMA
, vol.267
, pp. 1806-1809
-
-
Lipsitz, L.A.1
Goldberger, A.L.2
-
23
-
-
84895925833
-
The SIRT1 activator SRT1720 extends lifespan and improves health of mice fed a standard diet
-
Mitchell SJ, Martin-Montalvo A, Mercken EM, Palacios HH, Ward TM, Abulwerdi G, Minor RK, Vlasuk GP, Ellis JL, Sinclair DA, Dawson J, Allison DB, Zhang Y, Becker KG, Bernier M, de Cabo R (2014) The SIRT1 activator SRT1720 extends lifespan and improves health of mice fed a standard diet. Cell Rep. 6, 836-843.
-
(2014)
Cell Rep.
, vol.6
, pp. 836-843
-
-
Mitchell, S.J.1
Martin-Montalvo, A.2
Mercken, E.M.3
Palacios, H.H.4
Ward, T.M.5
Abulwerdi, G.6
Minor, R.K.7
Vlasuk, G.P.8
Ellis, J.L.9
Sinclair, D.A.10
Dawson, J.11
Allison, D.B.12
Zhang, Y.13
Becker, K.G.14
Bernier, M.15
de Cabo, R.16
-
25
-
-
47549088250
-
The NAD+-dependent deacetylases SIRT1 modulates CLOCK-mediated chromatin remodeling and circadian control
-
Nakahata Y, Kaluzova M, Grimaldi B, Sahar S, Hirayama J, Chen D, Guarente LP, Sassone-Corsi P (2008) The NAD+-dependent deacetylases SIRT1 modulates CLOCK-mediated chromatin remodeling and circadian control. Cell 134, 329-340.
-
(2008)
Cell
, vol.134
, pp. 329-340
-
-
Nakahata, Y.1
Kaluzova, M.2
Grimaldi, B.3
Sahar, S.4
Hirayama, J.5
Chen, D.6
Guarente, L.P.7
Sassone-Corsi, P.8
-
26
-
-
23444440343
-
Frailty and its definition: a worthy challenge
-
Rockwood K (2005) Frailty and its definition: a worthy challenge. J. Am. Geriatr. Soc. 53, 1069-1070.
-
(2005)
J. Am. Geriatr. Soc.
, vol.53
, pp. 1069-1070
-
-
Rockwood, K.1
-
27
-
-
8644224064
-
Sir2 mediates longevity in the fly through a pathway related to calorie restriction
-
Rogina B, Helfand SL (2004) Sir2 mediates longevity in the fly through a pathway related to calorie restriction. Proc. Natl Acad. Sci. U S A 101, 15998-16003.
-
(2004)
Proc. Natl Acad. Sci. U S A
, vol.101
, pp. 15998-16003
-
-
Rogina, B.1
Helfand, S.L.2
-
28
-
-
0014477918
-
Serum enzymes in the diagnosis of disease
-
Taylor WH (1969) Serum enzymes in the diagnosis of disease. Br. J. Anaesth. 41, 227-234.
-
(1969)
Br. J. Anaesth.
, vol.41
, pp. 227-234
-
-
Taylor, W.H.1
-
29
-
-
23844444818
-
Recent advances in blood-related proteomics
-
Thadikkaran L, Siegenthaler MA, Crettaz D, Queloz PA, Schneider P, Tissot JD (2005) Recent advances in blood-related proteomics. Proteomics 5, 3019-3034.
-
(2005)
Proteomics
, vol.5
, pp. 3019-3034
-
-
Thadikkaran, L.1
Siegenthaler, M.A.2
Crettaz, D.3
Queloz, P.A.4
Schneider, P.5
Tissot, J.D.6
-
30
-
-
0035826271
-
Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans
-
Tissenbaum HA, Guarente L (2001) Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans. Nature 410, 227-230.
-
(2001)
Nature
, vol.410
, pp. 227-230
-
-
Tissenbaum, H.A.1
Guarente, L.2
-
31
-
-
69549124156
-
High oxidative stress is correlated with frailty in elderly chinese
-
Wu IC, Shiesh SC, Kuo PH, Lin XZ (2009) High oxidative stress is correlated with frailty in elderly chinese. J. Am. Geriatr. Soc. 57, 1666-1671.
-
(2009)
J. Am. Geriatr. Soc.
, vol.57
, pp. 1666-1671
-
-
Wu, I.C.1
Shiesh, S.C.2
Kuo, P.H.3
Lin, X.Z.4
-
32
-
-
3242719545
-
Modulation of NF-kappaB-dependent transcription and cell survival by the SIRT1 deacetylase
-
Yeung F, Hoberg JE, Ramsey CS, Keller MD, Jones DR, Frye RA, Mayo MW (2004) Modulation of NF-kappaB-dependent transcription and cell survival by the SIRT1 deacetylase. EMBO J. 23, 2369-2380.
-
(2004)
EMBO J.
, vol.23
, pp. 2369-2380
-
-
Yeung, F.1
Hoberg, J.E.2
Ramsey, C.S.3
Keller, M.D.4
Jones, D.R.5
Frye, R.A.6
Mayo, M.W.7
|