P66Shc-SIRT1 Regulation of Oxidative Stress Protects Against Cardio-cerebral Vascular Disease

Molecular Neurobiology

Volumn 54, Issue 7, 2017, Pages 5277-5285

  Kong, Xiangyi ^a,b   Guan, Jian ^a   Li, Jun ^c   Wei, Junji ^a   Wang, Renzhi ^a  

^a PEKING UNION MEDICAL COLLEGE HOSPITAL   (China)

^b HARVARD MEDICAL SCHOOL   (United States)

^c HEBEI MEDICAL UNIVERSITY   (China)

Author keywords

Cardio cerebral vascular disease; Oxidative stress; P66Shc; Pathophysiological mechanism; SIRT1

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PLASMINOGEN ACTIVATOR INHIBITOR 1; PROTEIN P66; REACTIVE OXYGEN METABOLITE; SIRTUIN 1; TRANSCRIPTION FACTOR FKHRL1; PROTECTIVE AGENT; SHC TRANSFORMING PROTEIN 1;

AMINO TERMINAL SEQUENCE; ARTICLE; CARDIOVASCULAR DISEASE; CELL AGING; CEREBROVASCULAR ACCIDENT; CEREBROVASCULAR DISEASE; ENDOTHELIAL DYSFUNCTION; ENDOTHELIUM CELL; HUMAN; ISCHEMIA; MITOCHONDRIAL BIOGENESIS; NEUROPROTECTION; NONHUMAN; OXIDATIVE STRESS; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS; ANIMAL; DRUG EFFECT; METABOLISM; MITOCHONDRION;

ANIMALS; HUMANS; MITOCHONDRIA; OXIDATIVE STRESS; PROTECTIVE AGENTS; REACTIVE OXYGEN SPECIES; SIRTUIN 1; SRC HOMOLOGY 2 DOMAIN-CONTAINING, TRANSFORMING PROTEIN 1;

EID: 84984820665     PISSN: 08937648     EISSN: 15591182     Source Type: Journal    
DOI: 10.1007/s12035-016-0073-2     Document Type: Article

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