Up-regulation of nicotinamide phosphoribosyltransferase and increase of NAD+ levels by glucose restriction extend replicative lifespan of human fibroblast Hs68 cells

Biogerontology

Volumn 16, Issue 1, 2015, Pages 31-42

  Yang, Nae Cherng ^a,b   Song, Tuzz Ying ^c   Chang, Yan Zin ^a   Chen, Mei Yau ^a   Hu, Miao Lin ^d  

^a CHUNG SHAN MEDICAL UNIVERSITY   (Taiwan)

^b CHUNG SHAN MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^c DA YEH UNIVERSITY   (Taiwan)

^d NATIONAL CHUNG HSING UNIVERSITY   (Taiwan)

Author keywords

Calorie restriction; FK866; Hs68 cells; NAD+; Nicotinamide; Nicotinamide phosphoribosyltransferase

Indexed keywords

DAPORINAD; GLUCOSE; NICOTINAMIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE; NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE; SIRTINOL; SIRTUIN 1; ACRYLAMIDE DERIVATIVE; BENZAMIDE DERIVATIVE; CYTOKINE; N-(4-(1-BENZOYLPIPERIDIN-4-YL)BUTYL)-3-(PYRIDIN-3-YL)ACRYLAMIDE; NAPHTHOL DERIVATIVE; NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE, HUMAN; PIPERIDINE DERIVATIVE; SIRT1 PROTEIN, HUMAN;

ARTICLE; CELL DENSITY; CELL DIVISION; CELL STRUCTURE; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; FIBROBLAST; FIBROBLAST CULTURE; HUMAN; HUMAN CELL; IC50; LIQUID CHROMATOGRAPHY; PRIORITY JOURNAL; PROTEIN EXPRESSION; STEADY STATE; TANDEM MASS SPECTROMETRY; UPREGULATION; WESTERN BLOTTING; ANTAGONISTS AND INHIBITORS; CELL AGING; CELL CULTURE; CELL LINE; CELL PROLIFERATION; CYTOLOGY; DOSE RESPONSE; DRUG EFFECTS; METABOLISM; PHYSIOLOGY;

ACRYLAMIDES; BENZAMIDES; CELL AGING; CELL LINE; CELL PROLIFERATION; CELL SURVIVAL; CELLS, CULTURED; CYTOKINES; DOSE-RESPONSE RELATIONSHIP, DRUG; FIBROBLASTS; GLUCOSE; HUMANS; NAD; NAPHTHOLS; NIACINAMIDE; NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE; PIPERIDINES; SIRTUIN 1; UP-REGULATION;

EID: 84921847832     PISSN: 13895729     EISSN: 15736768     Source Type: Journal    
DOI: 10.1007/s10522-014-9528-x     Document Type: Article

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