Cytosolic malate dehydrogenase regulates senescence in human fibroblasts

Biogerontology

Volumn 13, Issue 5, 2012, Pages 525-536

  Lee, Seung Min ^a,b   Dho, So Hee ^a   Ju, Sung Kyu ^a   Maeng, Jin Soo ^c   Kim, Jeong Yoon ^b   Kwon, Ki Sun ^a  

^a Korea Research Institute of Bioscience and Biotechnology (KRIBB)   (South Korea)

^b Chungnam National University   (South Korea)

^c Korea Food Research Institute   (South Korea)

Author keywords

AMPK; MDH1; NAD NADH; Senescence; SIRT1

Indexed keywords

BETA GALACTOSIDASE; CYCLIN DEPENDENT KINASE INHIBITOR 1; CYCLIN DEPENDENT KINASE INHIBITOR 2A; CYTOSOLIC MALATE DEHYDROGENASE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; MALATE DEHYDROGENASE; NICOTINAMIDE ADENINE DINUCLEOTIDE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE; SIRTUIN 1; UNCLASSIFIED DRUG;

ARTICLE; CELL AGING; CELL DIVISION; CELL LEVEL; CELL STRUCTURE; CONTROLLED STUDY; CORRELATION ANALYSIS; CYTOSOL; ENZYME ACTIVATION; ENZYME ACTIVITY; FIBROBLAST; GENE SILENCING; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN CONTENT; PROTEIN FUNCTION;

BASE SEQUENCE; BLOTTING, WESTERN; CARBOHYDRATE METABOLISM; CELL AGING; CYTOSOL; DNA PRIMERS; FIBROBLASTS; GENE KNOCKDOWN TECHNIQUES; HUMANS; MALATE DEHYDROGENASE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA INTERFERENCE;

EID: 84870292564     PISSN: 13895729     EISSN: 15736768     Source Type: Journal    
DOI: 10.1007/s10522-012-9397-0     Document Type: Article

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