Curcumin attenuates hydrogen peroxide-induced premature senescence via the activation of SIRT1 in human umbilical vein endothelial cells

Biological and Pharmaceutical Bulletin

Volumn 38, Issue 8, 2015, Pages 1134-1141

  Sun, Yueliu ^a   Hu, Xiaorong ^a   Hu, Gangying ^a   Xu, Changwu ^a   Jiang, Hong ^a  

^a RENMIN HOSPITAL OF WUHAN UNIVERSITY   (China)

Author keywords

Curcumin; Endothelial senescence; Hydrogen peroxide; Silent information regulator 1 (SIRT1)

Indexed keywords

BETA ACTIN; BETA GALACTOSIDASE; CURCUMIN; ENDOTHELIAL NITRIC OXIDE SYNTHASE; HYDROGEN PEROXIDE; PROTEIN P21; REACTIVE OXYGEN METABOLITE; SILENT INFORMATION REGULATOR PROTEIN; SILENT INFORMATION REGULATOR PROTEIN 1; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; ANTIOXIDANT; GLB1 PROTEIN, HUMAN; NITRIC OXIDE; NOS3 PROTEIN, HUMAN; PLANT EXTRACT; SIRTUIN 1;

APOPTOSIS; ARTICLE; CELL CYCLE REGULATION; CELL DIVISION; CELL GROWTH; CELL PROLIFERATION; CELL PROTECTION; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVATION; ENZYME ACTIVITY; HUMAN; HUMAN CELL; IMMUNOBLOTTING; OXIDATIVE STRESS; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SENESCENCE; UMBILICAL VEIN ENDOTHELIAL CELL; WESTERN BLOTTING; CELL AGING; CELL CULTURE; CHEMISTRY; CURCUMA; CYTOLOGY; DRUG EFFECTS; METABOLISM; PHOSPHORYLATION; PHYSIOLOGY; VASCULAR ENDOTHELIUM;

ANTIOXIDANTS; APOPTOSIS; BETA-GALACTOSIDASE; CELL AGING; CELL DIVISION; CELLS, CULTURED; CURCUMA; CURCUMIN; DOWN-REGULATION; ENDOTHELIUM, VASCULAR; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; HYDROGEN PEROXIDE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE III; OXIDATIVE STRESS; PHOSPHORYLATION; PLANT EXTRACTS; RNA, SMALL INTERFERING; SIRTUIN 1;

EID: 84940947887     PISSN: 09186158     EISSN: 13475215     Source Type: Journal    
DOI: 10.1248/bpb.b15-00012     Document Type: Article

References (45)

1. Campisi J, d'Adda di Fagagna F. Cellular senescence: when bad things happen to good cells. Nat. Rev. Mol. Cell Biol., 8, 729-740 (2007).
2. Erusalimsky JD, Skene C. Mechanisms of endothelial senescence. Exp. Physiol., 94, 299-304 (2009).
3. Minamino T, Miyauchi H, Yoshida T, Ishida Y, Yoshida H, Komuro I. Endothelial cell senescence in human atherosclerosis: role of telomere in endothelial dysfunction. Circulation, 105, 1541-1544 (2002).
4. Bürrig KF. The endothelium of advanced arteriosclerotic plaques in humans. Arterioscler. Thromb., 11, 1678-1689 (1991).
5. Vasile E, Tomita Y, Brown LF, Kocher O, Dvorak HF. Differential expression of thymosin beta-10 by early passage and senescent vascular endothelium is modulated by VPF/VEGF: evidence for senescent endothelial cells in vivo at sites of atherosclerosis. FASEB Journal: Official Publication of the Federation of American Societies for Experimental Biology, 15, 458-466 (2001).
6. Minamino T, Yoshida T, Tateno K, Miyauchi H, Zou Y, Toko H, Komuro I. Ras induces vascular smooth muscle cell senescence and inflammation in human atherosclerosis. Circulation, 108, 2264-2269 (2003).
7. Vaziri H, Dessain SK, Ng Eaton E, Imai S-I, Frye RA, Pandita TK, Guarente L, Weinberg RA. hSIR2(SIRTfunctions as an NADdependent p53 deacetylase. Cell, 107, 149-159 (2001).
8. Saunders LR, Verdin E. Sirtuins: critical regulators at the crossroads between cancer and aging. Oncogene, 26, 5489-5504 (2007).
9. Ota H, Akishita M, Eto M, Iijima K, Kaneki M, Ouchi Y. Sirt1 modulates premature senescence-like phenotype in human endothelial cells. J. Mol. Cell. Cardiol., 43, 571-579 (2007).
10. Zu Y, Liu L, Lee MY, Xu C, Liang Y, Man RY, Vanhoutte PM, Wang Y. SIRT1 promotes proliferation and prevents senescence through targeting LKB1 in primary porcine aortic endothelial cells. Circ. Res., 106, 1384-1393 (2010).
11. Chen H, Wan Y, Zhou S, Lu Y, Zhang Z, Zhang R, Chen F, Hao D, Zhao X, Guo Z, Liu D, Liang C. Endothelium-specific SIRT1 overexpression inhibits hyperglycemia-induced upregulation of vascular cell senescence. Science China Life Sci., 55, 467-473 (2012).
12. Lestari ML, Indrayanto G. Curcumin. Profiles of Drug Substances, Excipients, and Related Methodology, 39, 113-204 (2014).
13. Dulbecco P, Savarino V. Therapeutic potential of curcumin in digestive diseases. World J. Gastroenterol., 19, 9256-9270 (2013).
14. Basnet P, Skalko-Basnet N. Curcumin: an anti-inflammatory molecule from a curry spice on the path to cancer treatment. Molecules, 16, 4567-4598 (2011).
15. Yang Y, Duan W, Lin Y, Yi W, Liang Z, Yan J, Wang N, Deng C, Zhang S, Li Y, Chen W, Yu S, Yi D, Jin Z. SIRT1 activation by curcumin pretreatment attenuates mitochondrial oxidative damage induced by myocardial ischemia reperfusion injury. Free Radic. Biol. Med., 65, 667-679 (2013).
16. Sun Q, Jia N, Wang W, Jin H, Xu J, Hu H. Activation of SIRT1 by curcumin blocks the neurotoxicity of amyloid-beta25-35 in rat cortical neurons. Biochem. Biophys. Res. Commun., 448, 89-94 (2014).
17. Queen BL, Tollefsbol TO. Polyphenols and aging. Current Aging Science, 3, 34-42 (2010).
18. Khurana S, Venkataraman K, Hollingsworth A, Piche M, Tai TC. Polyphenols: benefits to the cardiovascular system in health and in aging. Nutrients, 5, 3779-3827 (2013).
19. 2-induced oxidative stress and senescence via SirT1 activation. J. Atheroscler. Thromb., 17, 970-979 (2010).
20. Chung S, Yao H, Caito S, Hwang JW, Arunachalam G, Rahman I. Regulation of SIRT1 in cellular functions: role of polyphenols. Arch. Biochem. Biophys., 501, 79-90 (2010).
21. Ota H, Eto M, Kano MR, Kahyo T, Setou M, Ogawa S, Iijima K, Akishita M, Ouchi Y. Induction of endothelial nitric oxide synthase, SIRT1, and catalase by statins inhibits endothelial senescence through the Akt pathway. Arterioscler. Thromb. Vasc. Biol., 30, 2205-2211 (2010).
22. Wu Z, Uchi H, Morino-Koga S, Shi W, Furue M. Resveratrol inhibition of human keratinocyte proliferation via SIRT1/ARNT/ERK dependent downregulation of aquaporin 3. J. Dermatol. Sci., 75, 16-23 (2014).
23. 2-induced se nescence in human umbilical vein endothelial cells through SIRT1 activation. Molecular Medicine Reports, 7, 1865-1870 (2013).
24. Zhuge CC, Xu JY, Zhang J, Li W, Li P, Li Z, Chen L, Liu X, Shang P, Xu H, Lu Y, Wang F, Lu L, Xu GT. Fullerenol protects retinal pigment epithelial cells from oxidative stress-induced premature senescence via activating SIRT1. Invest. Ophthalmol. Vis. Sci., 55, 4628-4638 (2014).
25. Wang Y, Wu Z, Li D, Wang D, Wang X, Feng X, Xia M. Involvement of oxygen-regulated protein 150 in AMP-activated protein kinase-mediated alleviation of lipid-induced endoplasmic reticulum stress. J. Biol. Chem., 286, 11119-11131 (2011).
26. Chavez-Valdez R, Martin LJ, Flock DL, Northington FJ. Necrostatin- 1 attenuates mitochondrial dysfunction in neurons and astrocytes following neonatal hypoxia-ischemia. Neuroscience, 219, 192-203 (2012).
27. Yi TN, Zhao HY, Zhang JS, Shan HY, Meng X, Zhang J. Effect of aspirin on high glucose-induced senescence of endothelial cells. Chin. Med. J., 122, 3055-3061 (2009).
28. Hayflick L, Moorhead PS. The serial cultivation of human diploid cell strains. Exp. Cell Res., 25, 585-621 (1961).
29. Hayflick L. The limited in vitro lifetime of human diploid cell strains. Exp. Cell Res., 37, 614-636 (1965).
30. Itahana K, Campisi J, Dimri GP. Mechanisms of cellular senescence in human and mouse cells. Biogerontology, 5, 1-10 (2004).
31. Zhang H. Molecular signaling and genetic pathways of senescence: Its role in tumorigenesis and aging. J. Cell. Physiol., 210, 567-574 (2007).
32. Goligorsky MS, Chen J, Patschan S. Stress-induced premature senescence of endothelial cells: a perilous state between recovery and point of no return. Curr. Opin. Hematol., 16, 215-219 (2009).
33. Satyanarayana A, Wiemann SU, Buer J, Lauber J, Dittmar KE, Wustefeld T, Blasco MA, Manns MP, Rudolph KL. Telomere shortening impairs organ regeneration by inhibiting cell cycle re-entry of a subpopulation of cells. EMBO J., 22, 4003-4013 (2003).
34. Schmitt CA, Fridman JS, Yang M, Lee S, Baranov E, Hoffman RM, Lowe SW. A senescence program controlled by p53 and p16INK4a contributes to the outcome of cancer therapy. Cell, 109, 335-346 (2002).
35. Fenton M, Barker S, Kurz DJ, Erusalimsky JD. Cellular senescence after single and repeated balloon catheter denudations of rabbit carotid arteries. Arterioscler. Thromb. Vasc. Biol., 21, 220-226 (2001).
36. Chen J, Brodsky SV, Goligorsky DM, Hampel DJ, Li H, Gross SS, Goligorsky MS. Glycated collagen I induces premature senescencelike phenotypic changes in endothelial cells. Circ. Res., 90, 1290-1298 (2002).
37. Lee KS, Lee BS, Semnani S, Avanesian A, Um CY, Jeon HJ, Seong KM, Yu K, Min KJ, Jafari M. Curcumin extends life span, improves health span, and modulates the expression of age-associated aging genes in Drosophila melanogaster. Rejuvenation Res., 13, 561-570 (2010).
38. Kitani K, Osawa T, Yokozawa T. The effects of tetrahydrocurcumin and green tea polyphenol on the survival of male C57BL/6 mice. Biogerontology, 8, 567-573 (2007).
39. Li YB, Zhong ZF, Chen MW, Bao JL, Wu GS, Zhang QW, Lee SM, Hoi PM, Wang YT. Bisdemethoxycurcumin increases sirt1 to antagonize t-BHP-induced premature senescence in WI38 fibroblast cells. Evid. Based Complement. Alternat. Med., 2013, 851714 (2013).
40. Fleenor BS, Sindler AL, Marvi NK, Howell KL, Zigler ML, Yoshizawa M, Seals DR. Curcumin ameliorates arterial dysfunction and oxidative stress with aging. Exp. Gerontol., 48, 269-276 (2013).
41. Ota H, Eto M, Kano MR, Ogawa S, Iijima K, Akishita M, Ouchi Y. Cilostazol inhibits oxidative stress-induced premature senescence via upregulation of Sirt1 in human endothelial cells. Arterioscler. Thromb. Vasc. Biol., 28, 1634-1639 (2008).
42. Chen H, Liu X, Zhu W, Chen H, Hu X, Jiang Z, Xu Y, Wang L, Zhou Y, Chen P, Zhang N, Hu D, Zhang L, Wang Y, Xu Q, Wu R, Yu H, Wang J. SIRT1 ameliorates age-related senescence of mesenchymal stem cells via modulating telomere shelterin. Frontiers In Aging Neuroscience, 6, 103 (2014).
43. Jamal J, Mustafa MR, Wong PF. Paeonol protects against premature senescence in endothelial cells by modulating Sirtuin 1 pathway. J. Ethnopharmacol., 154, 428-436 (2014).
44. Zheng M, Qiao W, Cui J, Liu L, Liu H, Wang Z, Yan C. Hydrogen sulfide delays nicotinamide-induced premature senescence via upregulation of SIRT1 in human umbilical vein endothelial cells. Mol. Cell. Biochem., 393, 59-67 (2014).
45. 2-induced cellular senescence. Biol. Pharm. Bull., 31, 1265-1269 (2008).