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Volumn 105, Issue 38, 2008, Pages 14447-14452

A role for the mitochondrial deacetylase Sirt3 in regulating energy homeostasis

Author keywords

Acetylation; Complex; Electron transport; Sirtuins

Indexed keywords

ADENOSINE TRIPHOSPHATE; MITOCHONDRIAL PROTEIN; PROTEIN SIRTUIN 3; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); UNCLASSIFIED DRUG;

EID: 55749084738     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0803790105     Document Type: Article
Times cited : (1096)

References (26)
  • 1
    • 0023340731 scopus 로고
    • Four genes responsible for a position effect on expression from HML and HMR in Saccharomyces cerevisiae
    • Rine J, Herskowitz I (1987) Four genes responsible for a position effect on expression from HML and HMR in Saccharomyces cerevisiae. Genetics 116:9-22.
    • (1987) Genetics , vol.116 , pp. 9-22
    • Rine, J.1    Herskowitz, I.2
  • 2
    • 0037130175 scopus 로고    scopus 로고
    • Calorie restriction extends Saccharomyces cerevisiae life span by increasing respiration
    • Lin SJ, et al. (2002) Calorie restriction extends Saccharomyces cerevisiae life span by increasing respiration. Nature 418:344-348.
    • (2002) Nature , vol.418 , pp. 344-348
    • Lin, S.J.1
  • 3
    • 0033214237 scopus 로고    scopus 로고
    • The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms
    • Kaeberlein M, McVey M, Guarente L (1999) The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms. Genes Dev 13:2570-2580.
    • (1999) Genes Dev , vol.13 , pp. 2570-2580
    • Kaeberlein, M.1    McVey, M.2    Guarente, L.3
  • 4
    • 0035826271 scopus 로고    scopus 로고
    • Increased dosage of a sir-2 gene extends life span in Caenorhabditis elegans
    • Tissenbaum HA, Guarente L (2001) Increased dosage of a sir-2 gene extends life span in Caenorhabditis elegans. Nature 410:227-230.
    • (2001) Nature , vol.410 , pp. 227-230
    • Tissenbaum, H.A.1    Guarente, L.2
  • 5
    • 33751113602 scopus 로고    scopus 로고
    • Mammalian sirtuins - Emerging roles in physiology, aging, and calorie restriction
    • Haigis MC, Guarente LP (2006) Mammalian sirtuins - Emerging roles in physiology, aging, and calorie restriction. Genes Dev 20:2913-2921.
    • (2006) Genes Dev , vol.20 , pp. 2913-2921
    • Haigis, M.C.1    Guarente, L.P.2
  • 6
    • 0037108799 scopus 로고    scopus 로고
    • SIRT3, a human SIR2 homologue, is an NAD-dependent deacetylase localized to mitochondria
    • Onyango P, Celic I, McCaffery JM, Boeke JD, Feinberg AP (2002) SIRT3, a human SIR2 homologue, is an NAD-dependent deacetylase localized to mitochondria. Proc Natl Acad Sci USA 99:13653-13658.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 13653-13658
    • Onyango, P.1    Celic, I.2    McCaffery, J.M.3    Boeke, J.D.4    Feinberg, A.P.5
  • 7
    • 34247271282 scopus 로고    scopus 로고
    • +-dependent histone deacetylase that translocates to the mitochondria upon cellular stress
    • +-dependent histone deacetylase that translocates to the mitochondria upon cellular stress. Genes Dev 21:920-928.
    • (2007) Genes Dev , vol.21 , pp. 920-928
    • Scher, M.B.1    Vaquero, A.2    Reinberg, D.3
  • 8
    • 0037135972 scopus 로고    scopus 로고
    • The human silent information regulator (Sir)2 homologue hSIRT3 is a mitochondrial nicotinamide adenine dinucleotide-dependent deacetylase
    • Schwer B, North BJ, Frye RA, Ott M, Verdin E (2002) The human silent information regulator (Sir)2 homologue hSIRT3 is a mitochondrial nicotinamide adenine dinucleotide-dependent deacetylase. J Cell Biol 158:647-657.
    • (2002) J Cell Biol , vol.158 , pp. 647-657
    • Schwer, B.1    North, B.J.2    Frye, R.A.3    Ott, M.4    Verdin, E.5
  • 9
    • 17144424946 scopus 로고    scopus 로고
    • SIRT3, a mitochondrial sirtuin deacetylase, regulates mitochondrial function and thermogenesis in brown adipocytes
    • Shi T, Wang F, Stieren E, Tong Q (2005) SIRT3, a mitochondrial sirtuin deacetylase, regulates mitochondrial function and thermogenesis in brown adipocytes. J Biol Chem 280:13560-13567.
    • (2005) J Biol Chem , vol.280 , pp. 13560-13567
    • Shi, T.1    Wang, F.2    Stieren, E.3    Tong, Q.4
  • 10
    • 33748316536 scopus 로고    scopus 로고
    • SIRT4 inhibits glutamate dehydrogenase and opposes the effects of calorie restriction in pancreatic beta cells
    • Haigis MC, et al. (2006) SIRT4 inhibits glutamate dehydrogenase and opposes the effects of calorie restriction in pancreatic beta cells. Cell 126:941-954.
    • (2006) Cell , vol.126 , pp. 941-954
    • Haigis, M.C.1
  • 11
    • 37549002891 scopus 로고    scopus 로고
    • Mammalian Sir2 homolog SIRT3 regulates global mitochondrial lysine acetylation
    • Lombard DB, et al. (2007) Mammalian Sir2 homolog SIRT3 regulates global mitochondrial lysine acetylation. Mol Cell Biol 27:8807-8814.
    • (2007) Mol Cell Biol , vol.27 , pp. 8807-8814
    • Lombard, D.B.1
  • 12
    • 33745889628 scopus 로고    scopus 로고
    • Reversible lysine acetylation controls the activity of the mitochondrial enzyme acetyl-CoA synthetase 2
    • Schwer B, Bunkenborg J, Verdin RO, Andersen JS, Verdin E (2006) Reversible lysine acetylation controls the activity of the mitochondrial enzyme acetyl-CoA synthetase 2. Proc Natl Acad Sci USA 103:10224-10229.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 10224-10229
    • Schwer, B.1    Bunkenborg, J.2    Verdin, R.O.3    Andersen, J.S.4    Verdin, E.5
  • 13
    • 33745931074 scopus 로고    scopus 로고
    • Sirtuins deacetylate and activate mammalian acetyl-CoA synthetases
    • Hallows WC, Lee S, Denu JM (2006) Sirtuins deacetylate and activate mammalian acetyl-CoA synthetases. Proc Natl Acad Sci USA 103:10230-10235.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 10230-10235
    • Hallows, W.C.1    Lee, S.2    Denu, J.M.3
  • 14
    • 33746992118 scopus 로고    scopus 로고
    • Substrate and functional diversity of lysine acetylation revealed by a proteomics survey
    • Kim SC, et al. (2006) Substrate and functional diversity of lysine acetylation revealed by a proteomics survey. Mol Cell 23:607-618.
    • (2006) Mol Cell , vol.23 , pp. 607-618
    • Kim, S.C.1
  • 15
    • 9744240955 scopus 로고    scopus 로고
    • Focused proteomics: Towards a high throughput monoclonal antibody-based resolution of proteins for diagnosis of mitochondrial diseases
    • Murray J, Yonally S, Aggeler R, Marusich MF, Capaldi RA (2004) Focused proteomics: Towards a high throughput monoclonal antibody-based resolution of proteins for diagnosis of mitochondrial diseases. Biochim Biophys Acta 1659:206-211.
    • (2004) Biochim Biophys Acta , vol.1659 , pp. 206-211
    • Murray, J.1    Yonally, S.2    Aggeler, R.3    Marusich, M.F.4    Capaldi, R.A.5
  • 16
    • 29344473941 scopus 로고    scopus 로고
    • Proteomic analysis of succinate dehydrogenase and ubiquinol-cytochrome c reductase (Complex II and III) isolated by immunoprecipitation from bovine and mouse heart mitochondria
    • Schilling B, et al. (2006) Proteomic analysis of succinate dehydrogenase and ubiquinol-cytochrome c reductase (Complex II and III) isolated by immunoprecipitation from bovine and mouse heart mitochondria. Biochim Biophys Acta 1762:213-222.
    • (2006) Biochim Biophys Acta , vol.1762 , pp. 213-222
    • Schilling, B.1
  • 17
    • 0035913903 scopus 로고    scopus 로고
    • hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase
    • Vaziri H, et al. (2001) hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase. Cell 107:149-159.
    • (2001) Cell , vol.107 , pp. 149-159
    • Vaziri, H.1
  • 18
    • 0035913911 scopus 로고    scopus 로고
    • Negative control of p53 by Sir2alpha promotes cell survival under stress
    • Luo J, et al. (2001) Negative control of p53 by Sir2alpha promotes cell survival under stress. Cell 107:137-148.
    • (2001) Cell , vol.107 , pp. 137-148
    • Luo, J.1
  • 19
    • 3342967512 scopus 로고    scopus 로고
    • Is the failing heart energy starved? On using chemical energy to support cardiac function
    • Ingwall JS, Weiss RG (2004) Is the failing heart energy starved? On using chemical energy to support cardiac function. Circ Res 95:135-145.
    • (2004) Circ Res , vol.95 , pp. 135-145
    • Ingwall, J.S.1    Weiss, R.G.2
  • 20
    • 0032803255 scopus 로고    scopus 로고
    • Neonatal oxidative liver metabolism: Effects of hydrogen peroxide, a putative mediator of septic damage
    • Romeo C, Eaton S, Quant PA, Spitz L, Pierro A (1999) Neonatal oxidative liver metabolism: Effects of hydrogen peroxide, a putative mediator of septic damage. J Pediatr Surg 34:1107-1111.
    • (1999) J Pediatr Surg , vol.34 , pp. 1107-1111
    • Romeo, C.1    Eaton, S.2    Quant, P.A.3    Spitz, L.4    Pierro, A.5
  • 21
    • 0345222531 scopus 로고    scopus 로고
    • Mitochondrial function is differentially affected upon oxidative stress
    • Cardoso SM, Pereira C, Oliveira R (1999) Mitochondrial function is differentially affected upon oxidative stress. Free Radic Biol Med 26:3-13.
    • (1999) Free Radic Biol Med , vol.26 , pp. 3-13
    • Cardoso, S.M.1    Pereira, C.2    Oliveira, R.3
  • 22
    • 36148960929 scopus 로고    scopus 로고
    • Electron transport chain of Saccharomyces cerevisiae mitochondria is inhibited by H2O2 at succinate-cytochrome c oxidoreductase level without lipid peroxidation involvement
    • Cortes-Rojo C, et al. (2007) Electron transport chain of Saccharomyces cerevisiae mitochondria is inhibited by H2O2 at succinate-cytochrome c oxidoreductase level without lipid peroxidation involvement. Free Radic Res 41:1212-1223.
    • (2007) Free Radic Res , vol.41 , pp. 1212-1223
    • Cortes-Rojo, C.1
  • 23
    • 0032587877 scopus 로고    scopus 로고
    • Conditional mutation of Brca1 in mammary epithelial cells results in blunted ductal morphogenesis and tumour formation
    • Xu X, et al. (1999) Conditional mutation of Brca1 in mammary epithelial cells results in blunted ductal morphogenesis and tumour formation. Nat Genet 22:37-43.
    • (1999) Nat Genet , vol.22 , pp. 37-43
    • Xu, X.1
  • 24
    • 0032584068 scopus 로고    scopus 로고
    • The tumor suppressor SMAD4/DPC4 is essential for epiblast proliferation and mesoderm induction in mice
    • Yang X, Li C, Xu X, Deng C (1998) The tumor suppressor SMAD4/DPC4 is essential for epiblast proliferation and mesoderm induction in mice. Proc Natl Acad Sci USA 95:3667-3672.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 3667-3672
    • Yang, X.1    Li, C.2    Xu, X.3    Deng, C.4
  • 25
    • 0029917507 scopus 로고    scopus 로고
    • Fibroblast growth factor receptor 3 is a negative regulator of bone growth
    • Deng C, Wynshaw-Boris A, Zhou F, Kuo A, Leder P (1996) Fibroblast growth factor receptor 3 is a negative regulator of bone growth. Cell 84:911-921.
    • (1996) Cell , vol.84 , pp. 911-921
    • Deng, C.1    Wynshaw-Boris, A.2    Zhou, F.3    Kuo, A.4    Leder, P.5
  • 26
    • 0030008349 scopus 로고    scopus 로고
    • Efficient in vivo manipulation of mouse genomic sequences at the zygote stage
    • Lakso M, et al. (1996) Efficient in vivo manipulation of mouse genomic sequences at the zygote stage. Proc Natl Acad Sci USA 93:5860-5865.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 5860-5865
    • Lakso, M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.