-
1
-
-
0029621016
-
G protein-dependent activation of phospholipase C by adenosine A3 receptors in rat brain
-
Abbracchio MP, Brambilla R, Ceruti S, Kim HO, von Lubitz DK, Jacobson KA, and Cattabeni F (1995) G protein-dependent activation of phospholipase C by adenosine A3 receptors in rat brain. Mol Pharmacol 48:1038–1045.
-
(1995)
Mol Pharmacol
, vol.48
, pp. 1038-1045
-
-
Abbracchio, M.P.1
Brambilla, R.2
Ceruti, S.3
Kim, H.O.4
Von Lubitz, D.K.5
Jacobson, K.A.6
Cattabeni, F.7
-
2
-
-
0034743290
-
The A3 adenosine receptor induces cytoskeleton rearrangement in human astrocytoma cells via a specific action on Rho proteins
-
Abbracchio MP, Camurri A, Ceruti S, Cattabeni F, Falzano L, Giammarioli AM, Jacobson KA, Trincavelli L, Martini C, and Malorni W, et al. (2001) The A3 adenosine receptor induces cytoskeleton rearrangement in human astrocytoma cells via a specific action on Rho proteins. Ann N Y Acad Sci 939:63–73.
-
(2001)
Ann N Y Acad Sci
, vol.939
, pp. 63-73
-
-
Abbracchio, M.P.1
Camurri, A.2
Ceruti, S.3
Cattabeni, F.4
Falzano, L.5
Giammarioli, A.M.6
Jacobson, K.A.7
Trincavelli, L.8
Martini, C.9
Malorni, W.10
-
3
-
-
0031577677
-
The A3 adenosine receptor mediates cell spreading, reorganization of actin cytoskeleton, and distribution of Bcl-XL: Studies in human astroglioma cells
-
Abbracchio MP, Rainaldi G, Giammarioli AM, Ceruti S, Brambilla R, Cattabeni F, Barbieri D, Franceschi C, Jacobson KA, and Malorni W (1997) The A3 adenosine receptor mediates cell spreading, reorganization of actin cytoskeleton, and distribution of Bcl-XL: studies in human astroglioma cells. Biochem Biophys Res Commun 241:297–304.
-
(1997)
Biochem Biophys Res Commun
, vol.241
, pp. 297-304
-
-
Abbracchio, M.P.1
Rainaldi, G.2
Giammarioli, A.M.3
Ceruti, S.4
Brambilla, R.5
Cattabeni, F.6
Barbieri, D.7
Franceschi, C.8
Jacobson, K.A.9
Malorni, W.10
-
4
-
-
80054727886
-
Molecular mechanisms of A3 adenosine receptor-induced G1 cell cycle arrest and apoptosis in androgen-dependent and independent prostate cancer cell lines: Involvement of intrinsic pathway
-
Aghaei M, Panjehpour M, Karami-Tehrani F, and Salami S (2011) Molecular mechanisms of A3 adenosine receptor-induced G1 cell cycle arrest and apoptosis in androgen-dependent and independent prostate cancer cell lines: involvement of intrinsic pathway. J Cancer Res Clin Oncol 137:1511–1523.
-
(2011)
J Cancer Res Clin Oncol
, vol.137
, pp. 1511-1523
-
-
Aghaei, M.1
Panjehpour, M.2
Karami-Tehrani, F.3
Salami, S.4
-
5
-
-
0025064068
-
Activation of phospholipase C via adenosine receptors provides synergistic signals for secretion in antigenstimulated RBL-2H3 cells. Evidence for a novel adenosine receptor
-
Ali H, Cunha-Melo JR, Saul WF, and Beaven MA (1990) Activation of phospholipase C via adenosine receptors provides synergistic signals for secretion in antigenstimulated RBL-2H3 cells. Evidence for a novel adenosine receptor. J Biol Chem 265:745–753.
-
(1990)
J Biol Chem
, vol.265
, pp. 745-753
-
-
Ali, H.1
Cunha-Melo, J.R.2
Saul, W.F.3
Beaven, M.A.4
-
6
-
-
36849050373
-
Involvement of COX-1 in A3 adenosine receptor-mediated contraction through endothelium in mice aorta
-
Ansari HR, Nadeem A, Tilley SL, and Mustafa SJ (2007) Involvement of COX-1 in A3 adenosine receptor-mediated contraction through endothelium in mice aorta. Am J Physiol Heart Circ Physiol 293:H3448–H3455.
-
(2007)
Am J Physiol Heart Circ Physiol
, vol.293
, pp. H3448-H3455
-
-
Ansari, H.R.1
Nadeem, A.2
Tilley, S.L.3
Mustafa, S.J.4
-
7
-
-
84888385324
-
Immunity, inflammation and cancer: A leading role for adenosine
-
Antonioli L, Blandizzi C, Pacher P, and Haskó G (2013) Immunity, inflammation and cancer: a leading role for adenosine. Nat Rev Cancer 13:842–857.
-
(2013)
Nat Rev Cancer
, vol.13
, pp. 842-857
-
-
Antonioli, L.1
Blandizzi, C.2
Pacher, P.3
Haskó, G.4
-
8
-
-
77957223893
-
Control of enteric neuromuscular functions by purinergic A(3) receptors in normal rat distal colon and experimental bowel inflammation
-
Antonioli L, Fornai M, Colucci R, Ghisu N, Tuccori M, Awwad O, Bin A, Zoppellaro C, Castagliuolo I, and Gaion RM, et al. (2010) Control of enteric neuromuscular functions by purinergic A(3) receptors in normal rat distal colon and experimental bowel inflammation. Br J Pharmacol 161:856–871.
-
(2010)
Br J Pharmacol
, vol.161
, pp. 856-871
-
-
Antonioli, L.1
Fornai, M.2
Colucci, R.3
Ghisu, N.4
Tuccori, M.5
Awwad, O.6
Bin, A.7
Zoppellaro, C.8
Castagliuolo, I.9
Gaion, R.M.10
-
9
-
-
0030873005
-
Cloning, characterisation and chromosomal assignment of the human adenosine A3 receptor (ADORA3) gene
-
Atkinson MR, Townsend-Nicholson A, Nicholl JK, Sutherland GR, and Schofield PR (1997) Cloning, characterisation and chromosomal assignment of the human adenosine A3 receptor (ADORA3) gene. Neurosci Res 29:73–79.
-
(1997)
Neurosci Res
, vol.29
, pp. 73-79
-
-
Atkinson, M.R.1
Townsend-Nicholson, A.2
Nicholl, J.K.3
Sutherland, G.R.4
Schofield, P.R.5
-
10
-
-
0037962234
-
A3 adenosine receptor agonist IB-MECA reduces myocardial ischemia-reperfusion injury in dogs
-
Auchampach JA, Ge Z-D, Wan TC, Moore J, and Gross GJ (2003) A3 adenosine receptor agonist IB-MECA reduces myocardial ischemia-reperfusion injury in dogs. Am J Physiol Heart Circ Physiol 285:H607–H613.
-
(2003)
Am J Physiol Heart Circ Physiol
, vol.285
, pp. H607-H613
-
-
Auchampach, J.A.1
Ge, Z.-D.2
Wan, T.C.3
Moore, J.4
Gross, G.J.5
-
11
-
-
0030612660
-
Selective activation of A3 adenosine receptors with N6-(3-iodobenzyl)adenosine- 59-N-methyluronamide protects against myocardial stunning and infarction without hemodynamic changes in conscious rabbits
-
Auchampach JA, Rizvi A, Qiu Y, Tang XL, Maldonado C, Teschner S, and Bolli R (1997) Selective activation of A3 adenosine receptors with N6-(3-iodobenzyl)adenosine- 59-N-methyluronamide protects against myocardial stunning and infarction without hemodynamic changes in conscious rabbits. Circ Res 80:800–809.
-
(1997)
Circ Res
, vol.80
, pp. 800-809
-
-
Auchampach, J.A.1
Rizvi, A.2
Qiu, Y.3
Tang, X.L.4
Maldonado, C.5
Teschner, S.6
Bolli, R.7
-
12
-
-
77954348601
-
Treatment of dry eye syndrome with orally administered CF101: Data from a phase 2 clinical trial
-
Avni I, Garzozi HJ, Barequet IS, Segev F, Varssano D, Sartani G, Chetrit N, Bakshi E, Zadok D, and Tomkins O, et al. (2010) Treatment of dry eye syndrome with orally administered CF101: data from a phase 2 clinical trial. Ophthalmology 117: 1287–1293.
-
(2010)
Ophthalmology
, vol.117
, pp. 1287-1293
-
-
Avni, I.1
Garzozi, H.J.2
Barequet, I.S.3
Segev, F.4
Varssano, D.5
Sartani, G.6
Chetrit, N.7
Bakshi, E.8
Zadok, D.9
Tomkins, O.10
-
13
-
-
0037075142
-
Synthesis, biological activity, and molecular modeling investigation of new pyrazolo[4,3-e]-1,2,4-triazolo[1,5-c]pyrimidine derivatives as human A(3) adenosine receptor antagonists
-
Baraldi PG, Cacciari B, Moro S, Spalluto G, Pastorin G, Da Ros T, Klotz KN, Varani K, Gessi S, and Borea PA (2002) Synthesis, biological activity, and molecular modeling investigation of new pyrazolo[4,3-e]-1,2,4-triazolo[1,5-c]pyrimidine derivatives as human A(3) adenosine receptor antagonists. J Med Chem 45: 770–780.
-
(2002)
J Med Chem
, vol.45
, pp. 770-780
-
-
Baraldi, P.G.1
Cacciari, B.2
Moro, S.3
Spalluto, G.4
Pastorin, G.5
Da Ros, T.6
Klotz, K.N.7
Varani, K.8
Gessi, S.9
Borea, P.A.10
-
14
-
-
0033524031
-
Pyrazolo[4,3-e]-1,2,4-triazolo[1,5-c] pyrimidine derivatives as highly potent and selective human A(3) adenosine receptor antagonists
-
Baraldi PG, Cacciari B, Romagnoli R, Spalluto G, Klotz KN, Leung E, Varani K, Gessi S, Merighi S, and Borea PA (1999) Pyrazolo[4,3-e]-1,2,4-triazolo[1,5-c] pyrimidine derivatives as highly potent and selective human A(3) adenosine receptor antagonists. J Med Chem 42:4473–4478.
-
(1999)
J Med Chem
, vol.42
, pp. 4473-4478
-
-
Baraldi, P.G.1
Cacciari, B.2
Romagnoli, R.3
Spalluto, G.4
Klotz, K.N.5
Leung, E.6
Varani, K.7
Gessi, S.8
Merighi, S.9
Borea, P.A.10
-
15
-
-
0034649648
-
Pyrazolo[4,3-e]1,2,4-triazolo[1,5-c] pyrimidine derivatives as highly potent and selective human A(3) adenosine receptor antagonists: Influence of the chain at the N(8) pyrazole nitrogen
-
Baraldi PG, Cacciari B, Romagnoli R, Spalluto G, Moro S, Klotz K-N, Leung E, Varani K, Gessi S, and Merighi S, et al. (2000) Pyrazolo[4,3-e]1,2,4-triazolo[1,5-c] pyrimidine derivatives as highly potent and selective human A(3) adenosine receptor antagonists: influence of the chain at the N(8) pyrazole nitrogen. J Med Chem 43:4768–4780.
-
(2000)
J Med Chem
, vol.43
, pp. 4768-4780
-
-
Baraldi, P.G.1
Cacciari, B.2
Romagnoli, R.3
Spalluto, G.4
Moro, S.5
Klotz, K.-N.6
Leung, E.7
Varani, K.8
Gessi, S.9
Merighi, S.10
-
16
-
-
0345269287
-
Design, synthesis, and biological evaluation of C9- and C2-substituted pyrazolo[4,3-e]-1,2,4-triazolo[1,5-c] pyrimidines as new A2A and A3 adenosine receptors antagonists
-
Baraldi PG, Fruttarolo F, Tabrizi MA, Preti D, Romagnoli R, El-Kashef H, Moorman A, Varani K, Gessi S, and Merighi S, et al. (2003) Design, synthesis, and biological evaluation of C9- and C2-substituted pyrazolo[4,3-e]-1,2,4-triazolo[1,5-c] pyrimidines as new A2A and A3 adenosine receptors antagonists. JMed Chem46: 1229–1241.
-
(2003)
Jmed Chem46
, pp. 1229-1241
-
-
Baraldi, P.G.1
Fruttarolo, F.2
Tabrizi, M.A.3
Preti, D.4
Romagnoli, R.5
El-Kashef, H.6
Moorman, A.7
Varani, K.8
Gessi, S.9
Merighi, S.10
-
17
-
-
84863095992
-
Medicinal chemistry of A₃ adenosine receptor modulators: Pharmacological activities and therapeutic implications
-
Baraldi PG, Preti D, Borea PA, and Varani K (2012) Medicinal chemistry of A₃ adenosine receptor modulators: pharmacological activities and therapeutic implications. J Med Chem 55:5676–5703.
-
(2012)
J Med Chem
, vol.55
, pp. 5676-5703
-
-
Baraldi, P.G.1
Preti, D.2
Borea, P.A.3
Varani, K.4
-
18
-
-
0032078729
-
Apoptosis by 2-chloro-29-deoxyadenosine and 2-chloro-adenosine in human peripheral blood mononuclear cells
-
Barbieri D, Abbracchio MP, Salvioli S, Monti D, Cossarizza A, Ceruti S, Brambilla R, Cattabeni F, Jacobson KA, and Franceschi C (1998) Apoptosis by 2-chloro-29-deoxyadenosine and 2-chloro-adenosine in human peripheral blood mononuclear cells. Neurochem Int 32:493–504.
-
(1998)
Neurochem Int
, vol.32
, pp. 493-504
-
-
Barbieri, D.1
Abbracchio, M.P.2
Salvioli, S.3
Monti, D.4
Cossarizza, A.5
Ceruti, S.6
Brambilla, R.7
Cattabeni, F.8
Jacobson, K.A.9
Franceschi, C.10
-
19
-
-
77951025078
-
Adenosine blocks IFNg- induced phosphorylation of STAT1 on serine 727 to reduce macrophage activation
-
Barnholt KE, Kota RS, Aung HH, and Rutledge JC (2009) Adenosine blocks IFNg- induced phosphorylation of STAT1 on serine 727 to reduce macrophage activation. J Immunol 183:6767–6777.
-
(2009)
J Immunol
, vol.183
, pp. 6767-6777
-
-
Barnholt, K.E.1
Kota, R.S.2
Aung, H.H.3
Rutledge, J.C.4
-
20
-
-
80053107312
-
Inhibition of experimental autoimmune uveitis by the A3 adenosine receptor agonist CF101
-
Bar-Yehuda S, Luger D, Ochaion A, Cohen S, Patokaa R, Zozulya G, Silver PB, de Morales JM, Caspi RR, and Fishman P (2011) Inhibition of experimental autoimmune uveitis by the A3 adenosine receptor agonist CF101. Int J Mol Med 28: 727–731.
-
(2011)
Int J Mol Med
, vol.28
, pp. 727-731
-
-
Bar-Yehuda, S.1
Luger, D.2
Ochaion, A.3
Cohen, S.4
Patokaa, R.5
Zozulya, G.6
Silver, P.B.7
De Morales, J.M.8
Caspi, R.R.9
Fishman, P.10
-
21
-
-
18744393077
-
Agonists to the A3 adenosine receptor induce G-CSF production via NF-kappaB activation: A new class of myeloprotective agents
-
Bar-Yehuda S, Madi L, Barak D, Mittelman M, Ardon E, Ochaion A, Cohn S, and Fishman P (2002) Agonists to the A3 adenosine receptor induce G-CSF production via NF-kappaB activation: a new class of myeloprotective agents. Exp Hematol 30:1390–1398.
-
(2002)
Exp Hematol
, vol.30
, pp. 1390-1398
-
-
Bar-Yehuda, S.1
Madi, L.2
Barak, D.3
Mittelman, M.4
Ardon, E.5
Ochaion, A.6
Cohn, S.7
Fishman, P.8
-
22
-
-
70349778666
-
Induction of an antiinflammatory effect and prevention of cartilage damage in rat knee osteoarthritis by CF101 treatment
-
Bar-Yehuda S, Rath-Wolfson L, Del Valle L, Ochaion A, Cohen S, Patoka R, Zozulya G, Barer F, Atar E, and Piña-Oviedo S, et al. (2009) Induction of an antiinflammatory effect and prevention of cartilage damage in rat knee osteoarthritis by CF101 treatment. Arthritis Rheum 60:3061–3071.
-
(2009)
Arthritis Rheum
, vol.60
, pp. 3061-3071
-
-
Bar-Yehuda, S.1
Rath-Wolfson, L.2
Del Valle, L.3
Ochaion, A.4
Cohen, S.5
Patoka, R.6
Zozulya, G.7
Barer, F.8
Atar, E.9
Piña-Oviedo, S.10
-
23
-
-
35248857500
-
The anti-inflammatory effect of A3 adenosine receptor agonists: A novel targeted therapy for rheumatoid arthritis
-
Bar-Yehuda S, Silverman MH, Kerns WD, Ochaion A, Cohen S, and Fishman P (2007) The anti-inflammatory effect of A3 adenosine receptor agonists: a novel targeted therapy for rheumatoid arthritis. Expert Opin Investig Drugs 16: 1601–1613.
-
(2007)
Expert Opin Investig Drugs
, vol.16
, pp. 1601-1613
-
-
Bar-Yehuda, S.1
Silverman, M.H.2
Kerns, W.D.3
Ochaion, A.4
Cohen, S.5
Fishman, P.6
-
24
-
-
48749128664
-
The A3 adenosine receptor agonist CF102 induces apoptosis of hepatocellular carcinoma via de-regulation of the Wnt and NF-kappaB signal transduction pathways
-
Bar-Yehuda S, Stemmer SM, Madi L, Castel D, Ochaion A, Cohen S, Barer F, Zabutti A, Perez-Liz G, and Del Valle L, et al. (2008) The A3 adenosine receptor agonist CF102 induces apoptosis of hepatocellular carcinoma via de-regulation of the Wnt and NF-kappaB signal transduction pathways. Int J Oncol 33:287–295.
-
(2008)
Int J Oncol
, vol.33
, pp. 287-295
-
-
Bar-Yehuda, S.1
Stemmer, S.M.2
Madi, L.3
Castel, D.4
Ochaion, A.5
Cohen, S.6
Barer, F.7
Zabutti, A.8
Perez-Liz, G.9
Del Valle, L.10
-
25
-
-
56249109097
-
Decreased behavioral activation following caffeine, amphetamine and darkness in A3 adenosine receptor knock-out mice
-
Björklund O, Halldner-Henriksson L, Yang J, Eriksson TM, Jacobson MA, Daré E, and Fredholm BB (2008a) Decreased behavioral activation following caffeine, amphetamine and darkness in A3 adenosine receptor knock-out mice. Physiol Behav 95:668–676.
-
(2008)
Physiol Behav
, vol.95
, pp. 668-676
-
-
Björklund, O.1
Halldner-Henriksson, L.2
Yang, J.3
Eriksson, T.M.4
Jacobson, M.A.5
Daré, E.6
Fredholm, B.B.7
-
26
-
-
53049085661
-
Adenosine A1 and A3 receptors protect astrocytes from hypoxic damage
-
Björklund O, Shang M, Tonazzini I, Daré E, and Fredholm BB (2008b) Adenosine A1 and A3 receptors protect astrocytes from hypoxic damage. Eur J Pharmacol 596: 6–13.
-
(2008)
Eur J Pharmacol
, vol.596
, pp. 6-13
-
-
Björklund, O.1
Shang, M.2
Tonazzini, I.3
Daré, E.4
Fredholm, B.B.5
-
27
-
-
0030785819
-
The extracellular fluid of solid carcinomas contains immunosuppressive concentrations of adenosine
-
Blay J, White TD, and Hoskin DW (1997) The extracellular fluid of solid carcinomas contains immunosuppressive concentrations of adenosine. Cancer Res 57:2602– 2605.
-
(1997)
Cancer Res 57:2602–
-
-
Blay, J.1
White, T.D.2
Hoskin, D.W.3
-
28
-
-
0036891437
-
The pathophysiology of skeletal muscle ischemia and the reperfusion syndrome: A review
-
Blaisdell FW (2002) The pathophysiology of skeletal muscle ischemia and the reperfusion syndrome: a review. Cardiovasc Surg 10:620–630.
-
(2002)
Cardiovasc Surg
, vol.10
, pp. 620-630
-
-
Blaisdell, F.W.1
-
29
-
-
41149145189
-
Adenosine as a modulator of brain activity
-
Boison D (2007) Adenosine as a modulator of brain activity. Drug News Perspect 20: 607–611.
-
(2007)
Drug News Perspect
, vol.20
, pp. 607-611
-
-
Boison, D.1
-
30
-
-
39149122180
-
The adenosine kinase hypothesis of epileptogenesis
-
Boison D (2008) The adenosine kinase hypothesis of epileptogenesis. Prog Neurobiol 84:249–262.
-
(2008)
Prog Neurobiol
, vol.84
, pp. 249-262
-
-
Boison, D.1
-
31
-
-
0034571319
-
Can thermodynamic measurements of receptor binding yield information on drug affinity and efficacy?
-
Borea PA, Dalpiaz A, Varani K, Gilli P, and Gilli G (2000) Can thermodynamic measurements of receptor binding yield information on drug affinity and efficacy? Biochem Pharmacol 60:1549–1556.
-
(2000)
Biochem Pharmacol
, vol.60
, pp. 1549-1556
-
-
Borea, P.A.1
Dalpiaz, A.2
Varani, K.3
Gilli, P.4
Gilli, G.5
-
32
-
-
0031156985
-
Adenosine inhibits neutrophil degranulation in activated human whole blood: Involvement of adenosine A2 and A3 receptors
-
Bouma MG, Jeunhomme TM, Boyle DL, Dentener MA, Voitenok NN, van den Wildenberg FAJM, and Buurman WA (1997) Adenosine inhibits neutrophil degranulation in activated human whole blood: involvement of adenosine A2 and A3 receptors. J Immunol 158:5400–5408.
-
(1997)
J Immunol
, vol.158
, pp. 5400-5408
-
-
Bouma, M.G.1
Jeunhomme, T.M.2
Boyle, D.L.3
Dentener, M.A.4
Voitenok, N.N.5
Van Den Wildenberg, F.6
Buurman, W.A.7
-
33
-
-
0033758890
-
Adenosine A(1) and A(3) receptors mediate inhibition of synaptic transmission in rat cortical neurons
-
Brand A, Vissiennon Z, Eschke D, and Nieber K (2001) Adenosine A(1) and A(3) receptors mediate inhibition of synaptic transmission in rat cortical neurons. Neuropharmacology 40:85–95.
-
(2001)
Neuropharmacology
, vol.40
, pp. 85-95
-
-
Brand, A.1
Vissiennon, Z.2
Eschke, D.3
Nieber, K.4
-
34
-
-
33745598818
-
Cloning and pharmacological characterization of the equine adenosine A3 receptor
-
Brandon CI, Vandenplas M, Dookwah H, and Murray TF (2006) Cloning and pharmacological characterization of the equine adenosine A3 receptor. J Vet Pharmacol Ther 29:255–263.
-
(2006)
J Vet Pharmacol Ther
, vol.29
, pp. 255-263
-
-
Brandon, C.I.1
Vandenplas, M.2
Dookwah, H.3
Murray, T.F.4
-
35
-
-
0032823080
-
Inhibition of fMLP-triggered respiratory burst of human monocytes by adenosine: Involvement of A3 adenosine receptor
-
Broussas M, Cornillet-Lefèbvre P, Potron G, and Nguyen P (1999) Inhibition of fMLP-triggered respiratory burst of human monocytes by adenosine: involvement of A3 adenosine receptor. J Leukoc Biol 66:495–501.
-
(1999)
J Leukoc Biol
, vol.66
, pp. 495-501
-
-
Broussas, M.1
Cornillet-Lefèbvre, P.2
Potron, G.3
Nguyen, P.4
-
36
-
-
0036303892
-
Adenosine inhibits tissue factor expression by LPS-stimulated human monocytes: Involvement of the A3 adenosine receptor
-
Broussas M, Cornillet-Lefèbvre P, Potron G, and Nguyên P (2002) Adenosine inhibits tissue factor expression by LPS-stimulated human monocytes: involvement of the A3 adenosine receptor. Thromb Haemost 88:123–130.
-
(2002)
Thromb Haemost
, vol.88
, pp. 123-130
-
-
Broussas, M.1
Cornillet-Lefèbvre, P.2
Potron, G.3
Nguyên, P.4
-
37
-
-
77958572554
-
Testicular expression of Adora3i2 in Adora3 knockout mice reveals a role of mouse A3Ri2 and human A3Ri3 adenosine receptors in sperm
-
Burnett LA, Blais EM, Unadkat JD, Hille B, Tilley SL, and Babcock DF (2010) Testicular expression of Adora3i2 in Adora3 knockout mice reveals a role of mouse A3Ri2 and human A3Ri3 adenosine receptors in sperm. J Biol Chem 285: 33662–33670.
-
(2010)
J Biol Chem
, vol.285
, pp. 33662-33670
-
-
Burnett, L.A.1
Blais, E.M.2
Unadkat, J.D.3
Hille, B.4
Tilley, S.L.5
Babcock, D.F.6
-
40
-
-
84891133400
-
Purinergic signaling and blood vessels in health and disease
-
Burnstock G and Ralevic V (2014) Purinergic signaling and blood vessels in health and disease. Pharmacol Rev 66:102–192.
-
(2014)
Pharmacol Rev
, vol.66
, pp. 102-192
-
-
Burnstock, G.1
Ralevic, V.2
-
41
-
-
0043270551
-
Adenosine inhibits activation-induced T cell expression of CD2 and CD28 co-stimulatory molecules: Role of interleukin-2 and cyclic AMP signaling pathways
-
Butler JJ, Mader JS, Watson CL, Zhang H, Blay J, and Hoskin DW (2003) Adenosine inhibits activation-induced T cell expression of CD2 and CD28 co-stimulatory molecules: role of interleukin-2 and cyclic AMP signaling pathways. J Cell Biochem 89:975–91.
-
(2003)
J Cell Biochem
, vol.89
, pp. 91-975
-
-
Butler, J.J.1
Mader, J.S.2
Watson, C.L.3
Zhang, H.4
Blay, J.5
Hoskin, D.W.6
-
42
-
-
84871260407
-
Impairment of adenosine A3 receptor activity disrupts neutrophil migratory capacity and impacts innate immune function in vivo
-
Butler M, Sanmugalingam D, Burton VJ, Wilson T, Pearson R, Watson RP, Smith P, and Parkinson SJ (2012) Impairment of adenosine A3 receptor activity disrupts neutrophil migratory capacity and impacts innate immune function in vivo. Eur J Immunol 42:3358–3368.
-
(2012)
Eur J Immunol
, vol.42
, pp. 3358-3368
-
-
Butler, M.1
Sanmugalingam, D.2
Burton, V.J.3
Wilson, T.4
Pearson, R.5
Watson, R.P.6
Smith, P.7
Parkinson, S.J.8
-
43
-
-
84856404019
-
Pharmacological characterization of adenosine receptors on isolated human bronchi
-
Calzetta L, Spina D, Cazzola M, Page CP, Facciolo F, Rendina EA, and Matera MG (2011) Pharmacological characterization of adenosine receptors on isolated human bronchi. Am J Respir Cell Mol Biol 45:1222–1231.
-
(2011)
Am J Respir Cell Mol Biol
, vol.45
, pp. 1222-1231
-
-
Calzetta, L.1
Spina, D.2
Cazzola, M.3
Page, C.P.4
Facciolo, F.5
Rendina, E.A.6
Matera, M.G.7
-
44
-
-
84916234397
-
A3 adenosine receptor allosteric modulators
-
Can-fite Biopharma Ltd. (2010) A3 adenosine receptor allosteric modulators. US0144156.
-
(2010)
US0144156
-
-
Ltd, C.-F.B.1
-
45
-
-
0027338338
-
Adenosine A3 receptors: Two into one won’t go
-
Carruthers AM and Fozard JR (1993) Adenosine A3 receptors: two into one won’t go. Trends Pharmacol Sci 14:290–291.
-
(1993)
Trends Pharmacol Sci
, vol.14
, pp. 290-291
-
-
Carruthers, A.M.1
Fozard, J.R.2
-
46
-
-
84857062597
-
Anti-ischemic effects of multivalent dendrimeric A₃ adenosine receptor agonists in cultured cardiomyocytes and in the isolated rat heart
-
Chanyshev B, Shainberg A, Isak A, Litinsky A, Chepurko Y, Tosh DK, Phan K, Gao ZG, Hochhauser E, and Jacobson KA (2012) Anti-ischemic effects of multivalent dendrimeric A₃ adenosine receptor agonists in cultured cardiomyocytes and in the isolated rat heart. Pharmacol Res 65:338–346.
-
(2012)
Pharmacol Res
, vol.65
, pp. 338-346
-
-
Chanyshev, B.1
Shainberg, A.2
Isak, A.3
Litinsky, A.4
Chepurko, Y.5
Tosh, D.K.6
Phan, K.7
Gao, Z.G.8
Hochhauser, E.9
Jacobson, K.A.10
-
47
-
-
33845708770
-
ATP release guides neutrophil chemotaxis via P2Y2 and A3 receptors
-
Chen Y, Corriden R, Inoue Y, Yip L, Hashiguchi N, Zinkernagel A, Nizet V, Insel PA, and Junger WG (2006) ATP release guides neutrophil chemotaxis via P2Y2 and A3 receptors. Science 314:1792–1795.
-
(2006)
Science
, vol.314
, pp. 1792-1795
-
-
Chen, Y.1
Corriden, R.2
Inoue, Y.3
Yip, L.4
Hashiguchi, N.5
Zinkernagel, A.6
Nizet, V.7
Insel, P.A.8
Junger, W.G.9
-
48
-
-
84860895059
-
Controlling murine and rat chronic pain through A3 adenosine receptor activation
-
Chen Z, Janes K, Chen C, Doyle T, Bryant L, Tosh DK, Jacobson KA, and Salvemini D (2012) Controlling murine and rat chronic pain through A3 adenosine receptor activation. FASEB J 26:1855–1865.
-
(2012)
FASEB J
, vol.26
, pp. 1855-1865
-
-
Chen, Z.1
Janes, K.2
Chen, C.3
Doyle, T.4
Bryant, L.5
Tosh, D.K.6
Jacobson, K.A.7
Salvemini, D.8
-
49
-
-
80053271201
-
A3 adenosine receptor agonist reduces brain ischemic injury and inhibits inflammatory cell migration in rats
-
Choi IY, Lee JC, Ju C, Hwang S, Cho GS, Lee HW, Choi WJ, Jeong LS, and Kim WK (2011) A3 adenosine receptor agonist reduces brain ischemic injury and inhibits inflammatory cell migration in rats. Am J Pathol 179:2042–2052.
-
(2011)
Am J Pathol
, vol.179
, pp. 2042-2052
-
-
Choi, I.Y.1
Lee, J.C.2
Ju, C.3
Hwang, S.4
Cho, G.S.5
Lee, H.W.6
Choi, W.J.7
Jeong, L.S.8
Kim, W.K.9
-
50
-
-
0035829177
-
Differential gene expression of adenosine A1, A2a, A2b, and A3 receptors in the human enteric nervous system
-
Christofi FL, Zhang H, Yu JG, Guzman J, Xue J, Kim M, Wang Y-Z, and Cooke HJ (2001) Differential gene expression of adenosine A1, A2a, A2b, and A3 receptors in the human enteric nervous system. J Comp Neurol 439:46–64.
-
(2001)
J Comp Neurol
, vol.439
, pp. 46-64
-
-
Christofi, F.L.1
Zhang, H.2
Yu, J.G.3
Guzman, J.4
Xue, J.5
Kim, M.6
Wang, Y.-Z.7
Cooke, H.J.8
-
51
-
-
80053357815
-
Conformational changes in the G protein Gs induced by the b2 adrenergic receptor
-
Chung KY, Rasmussen SGF, Liu T, Li S, DeVree BT, Chae PS, Calinski D, Kobilka BK, Woods VL Jr, and Sunahara RK (2011) Conformational changes in the G protein Gs induced by the b2 adrenergic receptor. Nature 477:611–615.
-
(2011)
Nature
, vol.477
, pp. 611-615
-
-
Chung, K.Y.1
Rasmussen, S.2
Liu, T.3
Li, S.4
Devree, B.T.5
Chae, P.S.6
Calinski, D.7
Kobilka, B.K.8
Woods, V.L.9
Sunahara, R.K.10
-
52
-
-
84881333413
-
Inosine induces presynaptic inhibition of acetylcholine release by activation of A3 adenosine receptors at the mouse neuromuscular junction
-
Cinalli AR, Guarracino JF, Fernandez V, Roquel LI, and Losavio AS (2013) Inosine induces presynaptic inhibition of acetylcholine release by activation of A3 adenosine receptors at the mouse neuromuscular junction. Br J Pharmacol 169:1810–1823.
-
(2013)
Br J Pharmacol
, vol.169
, pp. 1810-1823
-
-
Cinalli, A.R.1
Guarracino, J.F.2
Fernandez, V.3
Roquel, L.I.4
Losavio, A.S.5
-
53
-
-
79958698872
-
CF102 an A3 adenosine receptor agonist mediates anti-tumor and anti-inflammatory effects in the liver
-
Cohen S, Stemmer SM, Zozulya G, Ochaion A, Patoka R, Barer F, Bar-Yehuda S, Rath-Wolfson L, Jacobson KA, and Fishman P (2011) CF102 an A3 adenosine receptor agonist mediates anti-tumor and anti-inflammatory effects in the liver. J Cell Physiol 226:2438–2447.
-
(2011)
J Cell Physiol
, vol.226
, pp. 2438-2447
-
-
Cohen, S.1
Stemmer, S.M.2
Zozulya, G.3
Ochaion, A.4
Patoka, R.5
Barer, F.6
Bar-Yehuda, S.7
Rath-Wolfson, L.8
Jacobson, K.A.9
Fishman, P.10
-
54
-
-
84881480493
-
Adenosine-A3 receptors in neutrophil microdomains promote the formation of bacteria-tethering cytonemes
-
Corriden R, Self T, Akong-Moore K, Nizet V, Kellam B, Briddon SJ, and Hill SJ (2013) Adenosine-A3 receptors in neutrophil microdomains promote the formation of bacteria-tethering cytonemes. EMBO Rep 14:726–732.
-
(2013)
EMBO Rep
, vol.14
, pp. 726-732
-
-
Corriden, R.1
Self, T.2
Akong-Moore, K.3
Nizet, V.4
Kellam, B.5
Briddon, S.J.6
Hill, S.J.7
-
55
-
-
0036783615
-
Overexpression of A(3) adenosine receptors decreases heart rate, preserves energetics, and protects ischemic hearts
-
Cross HR, Murphy E, Black RG, Auchampach J, and Steenbergen C (2002) Overexpression of A(3) adenosine receptors decreases heart rate, preserves energetics, and protects ischemic hearts. Am J Physiol Heart Circ Physiol 283:H1562–H1568.
-
(2002)
Am J Physiol Heart Circ Physiol
, vol.283
, pp. H1562-H1568
-
-
Cross, H.R.1
Murphy, E.2
Black, R.G.3
Auchampach, J.4
Steenbergen, C.5
-
56
-
-
84883461852
-
Anti-inflammatory effects of inosine in allergic lung inflammation in mice: Evidence for the participation of adenosine A2A and A 3 receptors
-
da Rocha Lapa F, de Oliveira AP, Accetturi BG, de Oliveira Martins I, Domingos HV, de Almeida Cabrini D, de Lima WT, and Santos AR (2013) Anti-inflammatory effects of inosine in allergic lung inflammation in mice: evidence for the participation of adenosine A2A and A 3 receptors. Purinergic Signal 9:325–336.
-
(2013)
Purinergic Signal
, vol.9
, pp. 325-336
-
-
Da Rocha Lapa, F.1
De Oliveira, A.P.2
Accetturi, B.G.3
De Oliveira Martins, I.4
Domingos, H.V.5
De Almeida Cabrini, D.6
De Lima, W.T.7
Santos, A.R.8
-
57
-
-
84857366473
-
Treatment of plaque-type psoriasis with oral CF101: Data from an exploratory randomized phase 2 clinical trial
-
David M, Akerman L, Ziv M, Kadurina M, Gospodinov D, Pavlotsky F, Yankova R, Kouzeva V, Ramon M, and Silverman MH, et al. (2012) Treatment of plaque-type psoriasis with oral CF101: data from an exploratory randomized phase 2 clinical trial. J Eur Acad Dermatol Venereol 26:361–367.
-
(2012)
J Eur Acad Dermatol Venereol
, vol.26
, pp. 361-367
-
-
David, M.1
Akerman, L.2
Ziv, M.3
Kadurina, M.4
Gospodinov, D.5
Pavlotsky, F.6
Yankova, R.7
Kouzeva, V.8
Ramon, M.9
Silverman, M.H.10
-
58
-
-
0030747295
-
Hypoxia-induced inhibition of adenosine kinase potentiates cardiac adenosine release
-
Decking UK, Schlieper G, Kroll K, and Schrader J (1997) Hypoxia-induced inhibition of adenosine kinase potentiates cardiac adenosine release. Circ Res 81:154–164.
-
(1997)
Circ Res
, vol.81
, pp. 154-164
-
-
Decking, U.K.1
Schlieper, G.2
Kroll, K.3
Schrader, J.4
-
59
-
-
59249094368
-
Adenosine analogs and electromagnetic fields inhibit prostaglandin E2 release in bovine synovial fibroblasts
-
De Mattei M, Varani K, Masieri FF, Pellati A, Ongaro A, Fini M, Cadossi R, Vincenzi F, Borea PA, and Caruso A (2009) Adenosine analogs and electromagnetic fields inhibit prostaglandin E2 release in bovine synovial fibroblasts. Osteoarthritis Cartilage 17:252–262.
-
(2009)
Osteoarthritis Cartilage
, vol.17
, pp. 252-262
-
-
De Mattei, M.1
Varani, K.2
Masieri, F.F.3
Pellati, A.4
Ongaro, A.5
Fini, M.6
Cadossi, R.7
Vincenzi, F.8
Borea, P.A.9
Caruso, A.10
-
60
-
-
0037472749
-
Knight DR, and Kong J, et al. (2003) 39-Aminoadenosine-59-uronamides: Discovery of the first highly selective agonist at the human adenosine A3 receptor
-
DeNinno MP, Masamune H, Chenard LK, DiRico KJ, Eller C, Etienne JB, Tickner JE, Kennedy SP, Knight DR, and Kong J, et al. (2003) 39-Aminoadenosine-59-uronamides: discovery of the first highly selective agonist at the human adenosine A3 receptor. J Med Chem 46:353–355.
-
J Med Chem
, vol.46
, pp. 353-355
-
-
Deninno, M.P.1
Masamune, H.2
Chenard, L.K.3
Dirico, K.J.4
Eller, C.5
Etienne, J.B.6
Tickner, J.E.7
Kennedy, S.P.8
-
61
-
-
80051770227
-
Oxygen/glucose deprivation induces a reduction in synaptic AMPA receptors on hippocampal CA3 neurons mediated by mGluR1 and adenosine A3 receptors
-
Dennis SH, Jaafari N, Cimarosti H, Hanley JG, Henley JM, and Mellor JR (2011) Oxygen/glucose deprivation induces a reduction in synaptic AMPA receptors on hippocampal CA3 neurons mediated by mGluR1 and adenosine A3 receptors. J Neurosci 31:11941–11952.
-
(2011)
J Neurosci
, vol.31
, pp. 11941-11952
-
-
Dennis, S.H.1
Jaafari, N.2
Cimarosti, H.3
Hanley, J.G.4
Henley, J.M.5
Mellor, J.R.6
-
62
-
-
77954768452
-
Direct evidence of chloride ion efflux in ischaemic and pharmacological preconditioning of cultured cardiomyocytes
-
Diaz RJ, Hinek A, and Wilson GJ (2010) Direct evidence of chloride ion efflux in ischaemic and pharmacological preconditioning of cultured cardiomyocytes. Cardiovasc Res 87:545–551.
-
(2010)
Cardiovasc Res
, vol.87
, pp. 545-551
-
-
Diaz, R.J.1
Hinek, A.2
Wilson, G.J.3
-
63
-
-
0142075367
-
Functional expression of adenosine A2A and A3 receptors in the mouse dendritic cell line XS-106
-
Dickenson JM, Reeder S, Rees B, Alexander S, and Kendall D (2003) Functional expression of adenosine A2A and A3 receptors in the mouse dendritic cell line XS-106. Eur J Pharmacol 474:43–51.
-
(2003)
Eur J Pharmacol
, vol.474
, pp. 43-51
-
-
Dickenson, J.M.1
Reeder, S.2
Rees, B.3
Alexander, S.4
Kendall, D.5
-
64
-
-
3242663566
-
Identification of adenosine A1 and A3 receptor subtypes in rat pial and intracerebral arteries
-
Di Tullio MA, Tayebati SK, and Amenta F (2004) Identification of adenosine A1 and A3 receptor subtypes in rat pial and intracerebral arteries. Neurosci Lett 366: 48–52.
-
(2004)
Neurosci Lett
, vol.366
, pp. 48-52
-
-
Di Tullio, M.A.1
Tayebati, S.K.2
Amenta, F.3
-
65
-
-
0029973397
-
Tissue distribution of adenosine receptor mRNAs in the rat
-
Dixon AK, Gubitz AK, Sirinathsinghji DJS, Richardson PJ, and Freeman TC (1996) Tissue distribution of adenosine receptor mRNAs in the rat. Br J Pharmacol 118: 1461–1468.
-
(1996)
Br J Pharmacol
, vol.118
, pp. 1461-1468
-
-
Dixon, A.K.1
Gubitz, A.K.2
Sirinathsinghji, D.3
Richardson, P.J.4
Freeman, T.C.5
-
66
-
-
0037717165
-
Impact of the aryl substituent kind and distance from pyrimido[2,1-f]purindiones on the adenosine receptor selectivity and antagonistic properties
-
Drabczyńska A, Schumacher B, Müller CE, Karolak-Wojciechowska J, Michalak B, Pekala E, and Kieć-Kononowicz K (2003) Impact of the aryl substituent kind and distance from pyrimido[2,1-f]purindiones on the adenosine receptor selectivity and antagonistic properties. Eur J Med Chem 38:397–402.
-
(2003)
Eur J Med Chem
, vol.38
, pp. 397-402
-
-
Drabczyńska, A.1
Schumacher, B.2
Müller, C.E.3
Karolak-Wojciechowska, J.4
Michalak, B.5
Pekala, E.6
Kieć-Kononowicz, K.7
-
67
-
-
84055178004
-
Protection from myocardial ischemia/reperfusion injury by a positive allosteric modulator of the A₃ adenosine receptor
-
Du L, Gao ZG, Nithipatikom K, Ijzerman AP, Veldhoven JP, Jacobson KA, Gross GJ, and Auchampach JA (2012) Protection from myocardial ischemia/reperfusion injury by a positive allosteric modulator of the A₃ adenosine receptor. J Pharmacol Exp Ther 340:210–217.
-
(2012)
J Pharmacol Exp Ther
, vol.340
, pp. 210-217
-
-
Du, L.1
Gao, Z.G.2
Nithipatikom, K.3
Ijzerman, A.P.4
Veldhoven, J.P.5
Jacobson, K.A.6
Gross, G.J.7
Auchampach, J.A.8
-
68
-
-
0031012121
-
Activation of hippocampal adenosine A3 receptors produces a desensitization of A1 receptormediated responses in rat hippocampus
-
Dunwiddie TV, Diao L, Kim HO, Jiang J-L, and Jacobson KA (1997) Activation of hippocampal adenosine A3 receptors produces a desensitization of A1 receptormediated responses in rat hippocampus. J Neurosci 17:607–614.
-
(1997)
J Neurosci
, vol.17
, pp. 607-614
-
-
Dunwiddie, T.V.1
Diao, L.2
Kim, H.O.3
Jiang, J.-L.4
Jacobson, K.A.5
-
69
-
-
79960514946
-
NADPH oxidase pathway is involved in aortic contraction induced by A3 adenosine receptor in mice
-
El-Awady MS, Ansari HR, Fil D, Tilley SL, and Mustafa SJ (2011) NADPH oxidase pathway is involved in aortic contraction induced by A3 adenosine receptor in mice. J Pharmacol Exp Ther 338:711–717.
-
(2011)
J Pharmacol Exp Ther
, vol.338
, pp. 711-717
-
-
El-Awady, M.S.1
Ansari, H.R.2
Fil, D.3
Tilley, S.L.4
Mustafa, S.J.5
-
70
-
-
0029853589
-
Characterization of adenosine receptors involved in adenosine-induced bronchoconstriction in allergic rabbits
-
el-Hashim A, D’Agostino B, Matera MG, and Page C (1996) Characterization of adenosine receptors involved in adenosine-induced bronchoconstriction in allergic rabbits. Br J Pharmacol 119:1262–1268.
-
(1996)
Br J Pharmacol
, vol.119
, pp. 1262-1268
-
-
El-Hashim, A.1
D’Agostino, B.2
Matera, M.G.3
Page, C.4
-
71
-
-
0036640709
-
Effector coupling of stably transfected human A3 adenosine receptors in CHO cells
-
Englert M, Quitterer U, and Klotz KN (2002) Effector coupling of stably transfected human A3 adenosine receptors in CHO cells. Biochem Pharmacol 64:61–65.
-
(2002)
Biochem Pharmacol
, vol.64
, pp. 61-65
-
-
Englert, M.1
Quitterer, U.2
Klotz, K.N.3
-
72
-
-
0037714059
-
Behavioral characterization of mice lacking the A3 adenosine receptor: Sensitivity to hypoxic neurodegeneration
-
Fedorova IM, Jacobson MA, Basile A, and Jacobson KA (2003) Behavioral characterization of mice lacking the A3 adenosine receptor: sensitivity to hypoxic neurodegeneration. Cell Mol Neurobiol 23:431–447.
-
(2003)
Cell Mol Neurobiol
, vol.23
, pp. 431-447
-
-
Fedorova, I.M.1
Jacobson, M.A.2
Basile, A.3
Jacobson, K.A.4
-
73
-
-
0028972108
-
Adenosine A2b receptors evoke interleukin-8 secretion in human mast cells. An enprofylline-sensitive mechanism with implications for asthma
-
Feoktistov I and Biaggioni I (1995) Adenosine A2b receptors evoke interleukin-8 secretion in human mast cells. An enprofylline-sensitive mechanism with implications for asthma. J Clin Invest 96:1979–1986.
-
(1995)
J Clin Invest
, vol.96
, pp. 1979-1986
-
-
Feoktistov, I.1
Biaggioni, I.2
-
74
-
-
0037459368
-
Mast cell-mediated stimulation of angiogenesis: Cooperative interaction between A2B and A3 adenosine receptors
-
Feoktistov I, Ryzhov S, Goldstein AE, and Biaggioni I (2003) Mast cell-mediated stimulation of angiogenesis: cooperative interaction between A2B and A3 adenosine receptors. Circ Res 92:485–492.
-
(2003)
Circ Res
, vol.92
, pp. 485-492
-
-
Feoktistov, I.1
Ryzhov, S.2
Goldstein, A.E.3
Biaggioni, I.4
-
75
-
-
84861099064
-
Adenosine A₂A and A₃receptors are involved in the human endothelial progenitor cells migration
-
Fernandez P, Jara C, Aguilera V, Caviedes L, Diaz F, Radojkovic C, Veas C, Lamperti L, Escudero C, and Aguayo C (2012) Adenosine A₂A and A₃ receptors are involved in the human endothelial progenitor cells migration. J Cardiovasc Pharmacol 59: 397–404.
-
(2012)
J Cardiovasc Pharmacol
, vol.59
, pp. 397-404
-
-
Fernandez, P.1
Jara, C.2
Aguilera, V.3
Caviedes, L.4
Diaz, F.5
Radojkovic, C.6
Veas, C.7
Lamperti, L.8
Escudero, C.9
Aguayo, C.10
-
76
-
-
84879365360
-
Functional tissue engineering in articular cartilage repair: Is there a role for electromagnetic biophysical stimulation?
-
Fini M, Pagani S, Giavaresi G, De Mattei M, Ongaro A, Varani K, Vincenzi F, Massari L, and Cadossi M (2013) Functional tissue engineering in articular cartilage repair: is there a role for electromagnetic biophysical stimulation? Tissue Eng Part B Rev 19:353–367.
-
(2013)
Tissue Eng Part B Rev
, vol.19
, pp. 353-367
-
-
Fini, M.1
Pagani, S.2
Giavaresi, G.3
De Mattei, M.4
Ongaro, A.5
Varani, K.6
Vincenzi, F.7
Massari, L.8
Cadossi, M.9
-
77
-
-
0042807352
-
Targeting the A3 adenosine receptor for cancer therapy: Inhibition of prostate carcinoma cell growth by A3AR agonist
-
Fishman P, Bar-Yehuda S, Ardon E, Rath-Wolfson L, Barrer F, Ochaion A, and Madi L (2003) Targeting the A3 adenosine receptor for cancer therapy: inhibition of prostate carcinoma cell growth by A3AR agonist. Anticancer Res 23 (3A): 2077–2083.
-
(2003)
Anticancer Res
, vol.23
, Issue.3A
, pp. 2077-2083
-
-
Fishman, P.1
Bar-Yehuda, S.2
Ardon, E.3
Rath-Wolfson, L.4
Barrer, F.5
Ochaion, A.6
Madi, L.7
-
78
-
-
0035478429
-
The A3 adenosine receptor as a new target for cancer therapy and chemoprotection
-
Fishman P, Bar-Yehuda S, Barer F, Madi L, Multani AS, and Pathak S (2001) The A3 adenosine receptor as a new target for cancer therapy and chemoprotection. Exp Cell Res 269:230–236.
-
(2001)
Exp Cell Res
, vol.269
, pp. 230-236
-
-
Fishman, P.1
Bar-Yehuda, S.2
Barer, F.3
Madi, L.4
Multani, A.S.5
Pathak, S.6
-
79
-
-
84859265040
-
Pharmacological and therapeutic effects of A3 adenosine receptor agonists
-
Fishman P, Bar-Yehuda S, Liang BT, and Jacobson KA (2012) Pharmacological and therapeutic effects of A3 adenosine receptor agonists. Drug Discov Today 17: 359–366.
-
(2012)
Drug Discov Today
, vol.17
, pp. 359-366
-
-
Fishman, P.1
Bar-Yehuda, S.2
Liang, B.T.3
Jacobson, K.A.4
-
81
-
-
70449564383
-
The PI3K-NF-kappaB signal transduction pathway is involved in mediating the anti-inflammatory effect of IB-MECA in adjuvant-induced arthritis
-
Fishman P, Bar-Yehuda S, Madi L, Rath-Wolfson L, Ochaion A, Cohen S, and Baharav E (2006) The PI3K-NF-kappaB signal transduction pathway is involved in mediating the anti-inflammatory effect of IB-MECA in adjuvant-induced arthritis. Arthritis Res Ther 8:R169.
-
(2006)
Arthritis Res Ther
, vol.8
-
-
Fishman, P.1
Bar-Yehuda, S.2
Madi, L.3
Rath-Wolfson, L.4
Ochaion, A.5
Cohen, S.6
Baharav, E.7
-
82
-
-
1942532883
-
An agonist to the A3 adenosine receptor inhibits colon carcinoma growth in mice via modulation of GSK-3 beta and NF-kappa B
-
Fishman P, Bar-Yehuda S, Ohana G, Barer F, Ochaion A, Erlanger A, and Madi L (2004) An agonist to the A3 adenosine receptor inhibits colon carcinoma growth in mice via modulation of GSK-3 beta and NF-kappa B. Oncogene 23:2465–2471.
-
(2004)
Oncogene
, vol.23
, pp. 2465-2471
-
-
Fishman, P.1
Bar-Yehuda, S.2
Ohana, G.3
Barer, F.4
Ochaion, A.5
Erlanger, A.6
Madi, L.7
-
83
-
-
0033921004
-
Adenosine acts as an inhibitor of lymphoma cell growth: A major role for the A3 adenosine receptor
-
Fishman P, Bar-Yehuda S, Ohana G, Pathak S, Wasserman L, Barer F, and Multani AS (2000) Adenosine acts as an inhibitor of lymphoma cell growth: a major role for the A3 adenosine receptor. Eur J Cancer 36:1452–1458.
-
(2000)
Eur J Cancer
, vol.36
, pp. 1452-1458
-
-
Fishman, P.1
Bar-Yehuda, S.2
Ohana, G.3
Pathak, S.4
Wasserman, L.5
Barer, F.6
Multani, A.S.7
-
84
-
-
70349314951
-
Adenosine receptors and cancer
-
Fishman P, Bar-Yehuda S, Synowitz M, Powell JD, Klotz KN, Gessi S, and Borea PA (2009) Adenosine receptors and cancer. Handbook Exp Pharmacol 193:399–441.
-
(2009)
Handbook Exp Pharmacol
, vol.193
, pp. 399-441
-
-
Fishman, P.1
Bar-Yehuda, S.2
Synowitz, M.3
Powell, J.D.4
Klotz, K.N.5
Gessi, S.6
Borea, P.A.7
-
85
-
-
0032527916
-
Adenosine and other low molecular weight factors released by muscle cells inhibit tumor cell growth
-
Fishman P, Bar-Yehuda S, and Vagman L (1998) Adenosine and other low molecular weight factors released by muscle cells inhibit tumor cell growth. Cancer Res 58: 3181–3187.
-
(1998)
Cancer Res
, vol.58
, pp. 3181-3187
-
-
Fishman, P.1
Bar-Yehuda, S.2
Vagman, L.3
-
86
-
-
84877272473
-
Targeting the A3 adenosine receptor for glaucoma treatment (review)
-
Fishman P, Cohen S, and Bar-Yehuda S (2013) Targeting the A3 adenosine receptor for glaucoma treatment (review). Mol Med Rep 7:1723–1725.
-
(2013)
Mol Med Rep
, vol.7
, pp. 1723-1725
-
-
Fishman, P.1
Cohen, S.2
Bar-Yehuda, S.3
-
87
-
-
0037030495
-
Evidence for involvement of Wnt signaling pathway in IB-MECA mediated suppression of melanoma cells
-
Fishman P, Madi L, Bar-Yehuda S, Barer F, Del Valle L, and Khalili K (2002b) Evidence for involvement of Wnt signaling pathway in IB-MECA mediated suppression of melanoma cells. Oncogene 21:4060–4064.
-
(2002)
Oncogene
, vol.21
, pp. 4060-4064
-
-
Fishman, P.1
Madi, L.2
Bar-Yehuda, S.3
Barer, F.4
Del Valle, L.5
Khalili, K.6
-
88
-
-
84864881916
-
-
Sci Transl Med 4:146ra108
-
Flögel U, Burghoff S, van Lent PL, Temme S, Galbarz L, Ding Z, El-Tayeb A, Huels S, Bönner F, and Borg N, et al. (2012) Selective activation of adenosine A2A receptors on immune cells by a CD73-dependent prodrug suppresses joint inflammation in experimental rheumatoid arthritis. Sci Transl Med 4:146ra108.
-
(2012)
Selective Activation of Adenosine A2A Receptors on Immune Cells by a Cd73-Dependent Prodrug Suppresses Joint Inflammation in Experimental Rheumatoid Arthritis
-
-
Flögel, U.1
Burghoff, S.2
Van Lent, P.L.3
Temme, S.4
Galbarz, L.5
Ding, Z.6
El-Tayeb, A.7
Huels, S.8
Bönner, F.9
Borg, N.10
-
89
-
-
15844400481
-
Modulation of cytokine release by purine receptors in patients with rheumatoid arthritis
-
Forrest CM, Harman G, McMillan RB, Stoy N, Stone TW, and Darlington LG (2005) Modulation of cytokine release by purine receptors in patients with rheumatoid arthritis. Clin Exp Rheumatol 23:89–92.
-
(2005)
Clin Exp Rheumatol
, vol.23
, pp. 89-92
-
-
Forrest, C.M.1
Harman, G.2
McMillan, R.B.3
Stoy, N.4
Stone, T.W.5
Darlington, L.G.6
-
90
-
-
79953058032
-
Cl-IB-MECA enhances TNF-a release in peritoneal macrophages stimulated with LPS
-
Forte G, Sorrentino R, Montinaro A, Pinto A, and Morello S (2011) Cl-IB-MECA enhances TNF-a release in peritoneal macrophages stimulated with LPS. Cytokine 54:161–166.
-
(2011)
Cytokine
, vol.54
, pp. 161-166
-
-
Forte, G.1
Sorrentino, R.2
Montinaro, A.3
Pinto, A.4
Morello, S.5
-
91
-
-
0037308772
-
Pharmacological analysis of calcium responses mediated by the human A3 adenosine receptor in monocyte-derived dendritic cells and recombinant cells
-
Fossetta J, Jackson J, Deno G, Fan X, Du XK, Bober L, Soudé-Bermejo A, de Bouteiller O, Caux C, and Lunn C, et al. (2003) Pharmacological analysis of calcium responses mediated by the human A3 adenosine receptor in monocyte-derived dendritic cells and recombinant cells. Mol Pharmacol 63:342–350.
-
(2003)
Mol Pharmacol
, vol.63
, pp. 342-350
-
-
Fossetta, J.1
Jackson, J.2
Deno, G.3
Fan, X.4
Du, X.K.5
Bober, L.6
Soudé-Bermejo, A.7
De Bouteiller, O.8
Caux, C.9
Lunn, C.10
-
92
-
-
4143095196
-
Activation of adenosine receptors inhibits tumor necrosis factor-alpha release by decreasing TNFalpha mRNA stability and p38 activity
-
Fotheringham JA, Mayne MB, Grant JA, and Geiger JD (2004) Activation of adenosine receptors inhibits tumor necrosis factor-alpha release by decreasing TNFalpha mRNA stability and p38 activity. Eur J Pharmacol 497:87–95.
-
(2004)
Eur J Pharmacol
, vol.497
, pp. 87-95
-
-
Fotheringham, J.A.1
Mayne, M.B.2
Grant, J.A.3
Geiger, J.D.4
-
93
-
-
0027339658
-
Adenosine A3 receptors mediate hypotension in the angiotensin II-supported circulation of the pithed rat
-
Fozard JR and Carruthers AM (1993) Adenosine A3 receptors mediate hypotension in the angiotensin II-supported circulation of the pithed rat. Br J Pharmacol 109:3–5.
-
(1993)
Br J Pharmacol
, vol.109
, pp. 3-5
-
-
Fozard, J.R.1
Carruthers, A.M.2
-
94
-
-
0029993349
-
Mast cell degranulation following adenosine A3 receptor activation in rats
-
Fozard JR, Pfannkuche H-J, and Schuurman H-J (1996) Mast cell degranulation following adenosine A3 receptor activation in rats. Eur J Pharmacol 298:293–297.
-
(1996)
Eur J Pharmacol
, vol.298
, pp. 293-297
-
-
Fozard, J.R.1
Pfannkuche, H.-J.2
Schuurman, H.-J.3
-
95
-
-
84859270374
-
From Hypertension (+) to Asthma: Interactions with the Adenosine A3 Receptor from a Personal Perspective
-
Borea PA, Springer, New York
-
Fozard JR (2010) From Hypertension (+) to Asthma: Interactions with the Adenosine A3 Receptor from a Personal Perspective, in A3 Adenosine Receptors from Cell Biology to Pharmacology and Therapeutics (Borea PA, ed) pp 3–26, Springer, New York.
-
(2010)
A3 Adenosine Receptors from Cell Biology to Pharmacology and Therapeutics
, pp. 3-26
-
-
Fozard, J.R.1
-
96
-
-
84898464790
-
Adenosine—a physiological or pathophysiological agent?
-
Fredholm BB (2014) Adenosine—a physiological or pathophysiological agent? J Mol Med (Berl) 92:201–206.
-
(2014)
J Mol Med (Berl)
, vol.92
, pp. 201-206
-
-
Fredholm, B.B.1
-
97
-
-
0035209620
-
International Union of Pharmacology. XXV. Nomenclature and classification of adenosine receptors
-
Fredholm BB, IJzerman AP, Jacobson KA, Klotz K-N, and Linden J (2001) International Union of Pharmacology. XXV. Nomenclature and classification of adenosine receptors. Pharmacol Rev 53:527–552.
-
(2001)
Pharmacol Rev
, vol.53
, pp. 527-552
-
-
Fredholm, B.B.1
Ijzerman, A.P.2
Jacobson, K.A.3
Klotz, K.-N.4
Linden, J.5
-
98
-
-
79952033865
-
International Union of Basic and Clinical Pharmacology. LXXXI. Nomenclature and classification of adenosine receptors—an update
-
Fredholm BB, IJzerman AP, Jacobson KA, Linden J, and Müller CE (2011) International Union of Basic and Clinical Pharmacology. LXXXI. Nomenclature and classification of adenosine receptors—an update. Pharmacol Rev 63:1–34.
-
(2011)
Pharmacol Rev
, vol.63
, pp. 1-34
-
-
Fredholm, B.B.1
Ijzerman, A.P.2
Jacobson, K.A.3
Linden, J.4
Müller, C.E.5
-
99
-
-
0028218322
-
Structure-activity relationships of N6-benzyladenosine-59-uronamides as A3-selective adenosine agonists
-
Gallo-Rodriguez C, Ji XD, Melman N, Siegman BD, Sanders LH, Orlina J, Fischer B, Pu Q, Olah ME, and van Galen PJ, et al. (1994) Structure-activity relationships of N6-benzyladenosine-59-uronamides as A3-selective adenosine agonists. J Med Chem 37:636–646.
-
(1994)
J Med Chem
, vol.37
, pp. 636-646
-
-
Gallo-Rodriguez, C.1
Ji, X.D.2
Melman, N.3
Siegman, B.D.4
Sanders, L.H.5
Orlina, J.6
Fischer, B.7
Pu, Q.8
Olah, M.E.9
Van Galen, P.J.10
-
100
-
-
0037166356
-
Identification by site-directed mutagenesis of residues involved in ligand recognition and activation of the human A3 adenosine receptor
-
Gao ZG, Chen A, Barak D, Kim SK, Müller CE, and Jacobson KA (2002) Identification by site-directed mutagenesis of residues involved in ligand recognition and activation of the human A3 adenosine receptor. J Biol Chem 277:19056–19063.
-
(2002)
J Biol Chem
, vol.277
, pp. 19056-19063
-
-
Gao, Z.G.1
Chen, A.2
Barak, D.3
Kim, S.K.4
Müller, C.E.5
Jacobson, K.A.6
-
102
-
-
0034746912
-
A3 adenosine receptor activation triggers phosphorylation of protein kinase B and protects rat basophilic leukemia 2H3 mast cells from apoptosis
-
Gao Z, Li BS, Day YJ, and Linden J (2001) A3 adenosine receptor activation triggers phosphorylation of protein kinase B and protects rat basophilic leukemia 2H3 mast cells from apoptosis. Mol Pharmacol 59:76–82.
-
(2001)
Mol Pharmacol
, vol.59
, pp. 76-82
-
-
Gao, Z.1
Li, B.S.2
Day, Y.J.3
Linden, J.4
-
103
-
-
80051544311
-
Functionally biased modulation of A(3) adenosine receptor agonist efficacy and potency by imidazoquinolinamine allosteric enhancers
-
Gao ZG, Verzijl D, Zweemer A, Ye K, Göblyös A, Ijzerman AP, and Jacobson KA (2011) Functionally biased modulation of A(3) adenosine receptor agonist efficacy and potency by imidazoquinolinamine allosteric enhancers. Biochem Pharmacol 82:658–668.
-
(2011)
Biochem Pharmacol
, vol.82
, pp. 658-668
-
-
Gao, Z.G.1
Verzijl, D.2
Zweemer, A.3
Ye, K.4
Göblyös, A.5
Ijzerman, A.P.6
Jacobson, K.A.7
-
104
-
-
84902290940
-
Adenosine A2B and A3 receptor location at the mouse neuromuscular junction
-
Garcia N, Priego M, Hurtado E, Obis T, Santafe MM, Tomàs M, Lanuza MA, and Tomàs J (2014) Adenosine A2B and A3 receptor location at the mouse neuromuscular junction. J Anat 225:109–17.
-
(2014)
J Anat
, vol.225
, pp. 109-117
-
-
Garcia, N.1
Priego, M.2
Hurtado, E.3
Obis, T.4
Santafe, M.M.5
Tomàs, M.6
Lanuza, M.A.7
Tomàs, J.8
-
105
-
-
0027179838
-
Synthesis of imidazo[1,2-c]pyrazolo[4,3-e]pyrimidines, pyrazolo[4,3-e]1,2,4-triazolo[1,5-c]pyrimidines and 1,2,4-triazolo[5,1-i]purines: New potent adenosine A2 receptor antagonists
-
Gatta F, Del Giudice MR, Borioni A, Borea PA, Dionisotti S, and Ongini E (1993) Synthesis of imidazo[1,2-c]pyrazolo[4,3-e]pyrimidines, pyrazolo[4,3-e]1,2,4-triazolo[1,5-c]pyrimidines and 1,2,4-triazolo[5,1-i]purines: new potent adenosine A2 receptor antagonists. Eur J Med Chem 28:569–576.
-
(1993)
Eur J Med Chem
, vol.28
, pp. 569-576
-
-
Gatta, F.1
Del Giudice, M.R.2
Borioni, A.3
Borea, P.A.4
Dionisotti, S.5
Ongini, E.6
-
106
-
-
77955470274
-
Activation of A1, A2A, or A3 adenosine receptors attenuates lung ischemiareperfusion injury
-
Gazoni LM, Walters DM, Unger EB, Linden J, Kron IL, and Laubach VE (2010) Activation of A1, A2A, or A3 adenosine receptors attenuates lung ischemiareperfusion injury. J Thorac Cardiovasc Surg 140:440–446.
-
(2010)
J Thorac Cardiovasc Surg
, vol.140
, pp. 440-446
-
-
Gazoni, L.M.1
Walters, D.M.2
Unger, E.B.3
Linden, J.4
Kron, I.L.5
Laubach, V.E.6
-
107
-
-
33751189857
-
Cl-IB-MECA [2-chloro-N6-(3-iodobenzyl)adenosine-59-N-methylcarboxamide] reduces ischemia/reperfusion injury in mice by activating the A3 adenosine receptor
-
Ge ZD, Peart JN, Kreckler LM, Wan TC, Jacobson MA, Gross GJ, and Auchampach JA (2006) Cl-IB-MECA [2-chloro-N6-(3-iodobenzyl)adenosine-59-N-methylcarboxamide] reduces ischemia/reperfusion injury in mice by activating the A3 adenosine receptor. J Pharmacol Exp Ther 319:1200–1210.
-
(2006)
J Pharmacol Exp Ther
, vol.319
, pp. 1200-1210
-
-
Ge, Z.D.1
Peart, J.N.2
Kreckler, L.M.3
Wan, T.C.4
Jacobson, M.A.5
Gross, G.J.6
Auchampach, J.A.7
-
108
-
-
77953713842
-
A(3) adenosine receptor activation during reperfusion reduces infarct size through actions on bone marrow-derived cells
-
Ge ZD, van der Hoeven D, Maas JE, Wan TC, and Auchampach JA (2010) A(3) adenosine receptor activation during reperfusion reduces infarct size through actions on bone marrow-derived cells. J Mol Cell Cardiol 49:280–286.
-
(2010)
J Mol Cell Cardiol
, vol.49
, pp. 280-286
-
-
Ge, Z.D.1
Van Der Hoeven, D.2
Maas, J.E.3
Wan, T.C.4
Auchampach, J.A.5
-
109
-
-
23644434435
-
Adenosine triggers preconditioning through MEK/ERK1/2 signalling pathway during hypoxia/reoxygenation in neonatal rat cardiomyocytes
-
Germack R and Dickenson JM (2005) Adenosine triggers preconditioning through MEK/ERK1/2 signalling pathway during hypoxia/reoxygenation in neonatal rat cardiomyocytes. J Mol Cell Cardiol 39:429–442.
-
(2005)
J Mol Cell Cardiol
, vol.39
, pp. 429-442
-
-
Germack, R.1
Dickenson, J.M.2
-
110
-
-
1342280328
-
Characterization of ERK1/2 signalling pathways induced by adenosine receptor subtypes in newborn rat cardiomyocytes
-
Germack R and Dickenson JM (2004) Characterization of ERK1/2 signalling pathways induced by adenosine receptor subtypes in newborn rat cardiomyocytes. Br J Pharmacol 141:329–339.
-
(2004)
Br J Pharmacol
, vol.141
, pp. 329-339
-
-
Germack, R.1
Dickenson, J.M.2
-
111
-
-
7444251760
-
Activation of protein kinase B by adenosine A1 and A3 receptors in newborn rat cardiomyocytes
-
Germack R, Griffin M, and Dickenson JM (2004) Activation of protein kinase B by adenosine A1 and A3 receptors in newborn rat cardiomyocytes. J Mol Cell Cardiol 37:989–999.
-
(2004)
J Mol Cell Cardiol
, vol.37
, pp. 989-999
-
-
Germack, R.1
Griffin, M.2
Dickenson, J.M.3
-
112
-
-
4444247043
-
Elevated expression of A3 adenosine receptors in human colorectal cancer is reflected in peripheral blood cells
-
Gessi S, Cattabriga E, Avitabile A, Gafa’ R, Lanza G, Cavazzini L, Bianchi N, Gambari R, Feo C, and Liboni A, et al. (2004a) Elevated expression of A3 adenosine receptors in human colorectal cancer is reflected in peripheral blood cells. Clin Cancer Res 10:5895–5901.
-
(2004)
Clin Cancer Res
, vol.10
, pp. 5895-5901
-
-
Gessi, S.1
Cattabriga, E.2
Avitabile, A.3
Gafa’, R.4
Lanza, G.5
Cavazzini, L.6
Bianchi, N.7
Gambari, R.8
Feo, C.9
Liboni, A.10
-
113
-
-
73849123855
-
Adenosine modulates HIF-1alpha, VEGF, IL-8, and foam cell formation in a human model of hypoxic foam cells
-
Gessi S, Fogli E, Sacchetto V, Merighi S, Varani K, Preti D, Leung E, Maclennan S, and Borea PA (2010a) Adenosine modulates HIF-1alpha, VEGF, IL-8, and foam cell formation in a human model of hypoxic foam cells. Arterioscler Thromb Vasc Biol 30:90–97.
-
(2010)
Arterioscler Thromb Vasc Biol
, vol.30
, pp. 90-97
-
-
Gessi, S.1
Fogli, E.2
Sacchetto, V.3
Merighi, S.4
Varani, K.5
Preti, D.6
Leung, E.7
Maclennan, S.8
Borea, P.A.9
-
114
-
-
37349029453
-
Thermodynamics of A2B adenosine receptor binding discriminates agonistic from antagonistic behaviour
-
Gessi S, Fogli E, Sacchetto V, Varani K, Merighi S, Leung E, Lennan SM, and Borea PA (2008a) Thermodynamics of A2B adenosine receptor binding discriminates agonistic from antagonistic behaviour. Biochem Pharmacol 75:562–569.
-
(2008)
Biochem Pharmacol
, vol.75
, pp. 562-569
-
-
Gessi, S.1
Fogli, E.2
Sacchetto, V.3
Varani, K.4
Merighi, S.5
Leung, E.6
Lennan, S.M.7
Borea, P.A.8
-
115
-
-
81555196344
-
Adenosine receptor targeting in health and disease
-
Gessi S, Merighi S, Fazzi D, Stefanelli A, Varani K, and Borea PA (2011a) Adenosine receptor targeting in health and disease. Expert Opin Investig Drugs 20: 1591–1609.
-
(2011)
Expert Opin Investig Drugs
, vol.20
, pp. 1591-1609
-
-
Gessi, S.1
Merighi, S.2
Fazzi, D.3
Stefanelli, A.4
Varani, K.5
Borea, P.A.6
-
116
-
-
79953210022
-
Adenosine receptors and cancer
-
Gessi S, Merighi S, Sacchetto V, Simioni C, and Borea PA (2011b) Adenosine receptors and cancer. Biochim Biophys Acta 1808:1400–1412.
-
(2011)
Biochim Biophys Acta
, vol.1808
, pp. 1400-1412
-
-
Gessi, S.1
Merighi, S.2
Sacchetto, V.3
Simioni, C.4
Borea, P.A.5
-
117
-
-
84883482212
-
A(1) and A(3) adenosine receptors inhibit LPS-induced hypoxia-inducible factor-1 accumulation in murine astrocytes
-
Gessi S, Merighi S, Stefanelli A, Fazzi D, Varani K, and Borea PA (2013) A(1) and A(3) adenosine receptors inhibit LPS-induced hypoxia-inducible factor-1 accumulation in murine astrocytes. Pharmacol Res 76:157–170.
-
(2013)
Pharmacol Res
, vol.76
, pp. 157-170
-
-
Gessi, S.1
Merighi, S.2
Stefanelli, A.3
Fazzi, D.4
Varani, K.5
Borea, P.A.6
-
118
-
-
84865052094
-
Downregulation of A(1) and A(2B) adenosine receptors in human trisomy 21 mesenchymal cells from first-trimester chorionic villi
-
Gessi S, Merighi S, Stefanelli A, Mirandola P, Bonfatti A, Fini S, Sensi A, Marci R, Varani K, and Borea PA, et al. (2012) Downregulation of A(1) and A(2B) adenosine receptors in human trisomy 21 mesenchymal cells from first-trimester chorionic villi. Biochim Biophys Acta 1822:1660–1670.
-
(2012)
Biochim Biophys Acta
, vol.1822
, pp. 1660-1670
-
-
Gessi, S.1
Merighi, S.2
Stefanelli, A.3
Mirandola, P.4
Bonfatti, A.5
Fini, S.6
Sensi, A.7
Marci, R.8
Varani, K.9
Borea, P.A.10
-
119
-
-
34247642621
-
Adenosine receptors in colon carcinoma tissues and colon tumoral cell lines: Focus on the A(3) adenosine subtype
-
Gessi S, Merighi S, Varani K, Cattabriga E, Benini A, Mirandola P, Leung E, Mac Lennan S, Feo C, and Baraldi S, et al. (2007) Adenosine receptors in colon carcinoma tissues and colon tumoral cell lines: focus on the A(3) adenosine subtype. J Cell Physiol 211:826–836.
-
(2007)
J Cell Physiol
, vol.211
, pp. 826-836
-
-
Gessi, S.1
Merighi, S.2
Varani, K.3
Cattabriga, E.4
Benini, A.5
Mirandola, P.6
Leung, E.7
Mac Lennan, S.8
Feo, C.9
Baraldi, S.10
-
120
-
-
36549081419
-
The A3 adenosine receptor: An enigmatic player in cell biology
-
Gessi S, Merighi S, Varani K, Leung E, Mac Lennan S, and Borea PA (2008b) The A3 adenosine receptor: an enigmatic player in cell biology. Pharmacol Ther 117: 123–140.
-
(2008)
Pharmacol Ther
, vol.117
, pp. 123-140
-
-
Gessi, S.1
Merighi, S.2
Varani, K.3
Leung, E.4
Mac Lennan, S.5
Borea, P.A.6
-
121
-
-
84900278247
-
A3 adenosine receptor regulation of cells of the immune system and modulation of inflammation
-
Borea PA, Springer, New York
-
Gessi S, Sacchetto V, Fogli E, and Fozard J (2009) A3 adenosine receptor regulation of cells of the immune system and modulation of inflammation, in A3 Adenosine Receptors from Cell Biology to Pharmacology and Therapeutics (Borea PA ed) pp 235–256, Springer, New York.
-
(2009)
A3 Adenosine Receptors from Cell Biology to Pharmacology and Therapeutics
, pp. 235-256
-
-
Gessi, S.1
Sacchetto, V.2
Fogli, E.3
Fozard, J.4
-
122
-
-
77649181282
-
Modulation of metalloproteinase-9 in U87MG glioblastoma cells by A3 adenosine receptors
-
Gessi S, Sacchetto V, Fogli E, Merighi S, Varani K, Baraldi PG, Tabrizi MA, Leung E, Maclennan S, and Borea PA (2010b) Modulation of metalloproteinase-9 in U87MG glioblastoma cells by A3 adenosine receptors. Biochem Pharmacol 79:1483–1495.
-
(2010)
Biochem Pharmacol
, vol.79
, pp. 1483-1495
-
-
Gessi, S.1
Sacchetto, V.2
Fogli, E.3
Merighi, S.4
Varani, K.5
Baraldi, P.G.6
Tabrizi, M.A.7
Leung, E.8
Maclennan, S.9
Borea, P.A.10
-
123
-
-
10744223679
-
Expression of A3 adenosine receptors in human lymphocytes: Up-regulation in T cell activation
-
Gessi S, Varani K, Merighi S, Cattabriga E, Avitabile A, Gavioli R, Fortini C, Leung E, Mac Lennan S, and Borea PA (2004b) Expression of A3 adenosine receptors in human lymphocytes: up-regulation in T cell activation. Mol Pharmacol 65: 711–719.
-
(2004)
Mol Pharmacol
, vol.65
, pp. 711-719
-
-
Gessi, S.1
Varani, K.2
Merighi, S.3
Cattabriga, E.4
Avitabile, A.5
Gavioli, R.6
Fortini, C.7
Leung, E.8
Mac Lennan, S.9
Borea, P.A.10
-
124
-
-
0036156443
-
A(3) adenosine receptors in human neutrophils and promyelocytic HL60 cells: A pharmacological and biochemical study
-
Gessi S, Varani K, Merighi S, Cattabriga E, Iannotta V, Leung E, Baraldi PG, and Borea PA (2002) A(3) adenosine receptors in human neutrophils and promyelocytic HL60 cells: a pharmacological and biochemical study. Mol Pharmacol 61:415–424.
-
(2002)
Mol Pharmacol
, vol.61
, pp. 415-424
-
-
Gessi, S.1
Varani, K.2
Merighi, S.3
Cattabriga, E.4
Iannotta, V.5
Leung, E.6
Baraldi, P.G.7
Borea, P.A.8
-
125
-
-
0034840465
-
Pharmacological and biochemical characterization of A3 adenosine receptors in Jurkat T cells
-
Gessi S, Varani K, Merighi S, Morelli A, Ferrari D, Leung E, Baraldi PG, Spalluto G, and Borea PA (2001) Pharmacological and biochemical characterization of A3 adenosine receptors in Jurkat T cells. Br J Pharmacol 134:116–126.
-
(2001)
Br J Pharmacol
, vol.134
, pp. 116-126
-
-
Gessi, S.1
Varani, K.2
Merighi, S.3
Morelli, A.4
Ferrari, D.5
Leung, E.6
Baraldi, P.G.7
Spalluto, G.8
Borea, P.A.9
-
126
-
-
84916207976
-
A3 adenosine receptor allosteric modulators
-
Goblyos A, Brussee J, Ijzerman AP, Gao ZJ, and Jacobson K (2009), inventors, Government of the USA, assignee. A3 adenosine receptor allosteric modulators. US patent 20090054476 A1. 26 Feb 2009.
-
(2009)
US Patent 20090054476 A1
-
-
Goblyos, A.1
Brussee, J.2
Ijzerman, A.P.3
Gao, Z.J.4
-
127
-
-
79961173593
-
Disparity in Fc«RI-induced degranulation of primary human lung and skin mast cells exposed to adenosine
-
Gomez G, Zhao W, and Schwartz LB (2011) Disparity in Fc«RI-induced degranulation of primary human lung and skin mast cells exposed to adenosine. J Clin Immunol 31:479–487.
-
(2011)
J Clin Immunol
, vol.31
, pp. 479-487
-
-
Gomez, G.1
Zhao, W.2
Schwartz, L.B.3
-
128
-
-
84890214544
-
A3 Adenosine receptors mediate oligodendrocyte death and ischemic damage to optic nerve
-
González-Fernández E, Sánchez-Gómez MV, Pérez-Samartín A, Arellano RO, and Matute C (2014) A3 Adenosine receptors mediate oligodendrocyte death and ischemic damage to optic nerve. Glia 62:199–216.
-
(2014)
Glia
, vol.62
, pp. 199-216
-
-
González-Fernández, E.1
Sánchez-Gómez, M.V.2
Pérez-Samartín, A.3
Arellano, R.O.4
Matute, C.5
-
129
-
-
84874095925
-
Novel effects of adenosine receptors on pericellular hyaluronan matrix: Implications for human smooth muscle cell phenotype and interactions with monocytes during atherosclerosis
-
Grandoch M, Hoffmann J, Röck K, Wenzel F, Oberhuber A, Schelzig H, and Fischer JW (2013) Novel effects of adenosine receptors on pericellular hyaluronan matrix: implications for human smooth muscle cell phenotype and interactions with monocytes during atherosclerosis. Basic Res Cardiol 108:340.
-
(2013)
Basic Res Cardiol
, vol.108
-
-
Grandoch, M.1
Hoffmann, J.2
Röck, K.3
Wenzel, F.4
Oberhuber, A.5
Schelzig, H.6
Fischer, J.W.7
-
130
-
-
0344687251
-
Adenosine A3 receptor-mediated regulation of p38 and extracellular-regulated kinase ERK1/2 via phosphatidylinositol-39-kinase
-
Hammarberg C, Fredholm BB, and Schulte G (2004) Adenosine A3 receptor-mediated regulation of p38 and extracellular-regulated kinase ERK1/2 via phosphatidylinositol-39-kinase. Biochem Pharmacol 67:129–134.
-
(2004)
Biochem Pharmacol
, vol.67
, pp. 129-134
-
-
Hammarberg, C.1
Fredholm, B.B.2
Schulte, G.3
-
131
-
-
0042731679
-
Evidence for functional adenosine A3 receptors in microglia cells
-
Hammarberg C, Schulte G, and Fredholm BB (2003) Evidence for functional adenosine A3 receptors in microglia cells. J Neurochem 86:1051–1054.
-
(2003)
J Neurochem
, vol.86
, pp. 1051-1054
-
-
Hammarberg, C.1
Schulte, G.2
Fredholm, B.B.3
-
132
-
-
0029089476
-
A role for mast cells in adenosine A3 receptor-mediated hypotension in the rat
-
Hannon JP, Pfannkuche HJ, and Fozard JR (1995) A role for mast cells in adenosine A3 receptor-mediated hypotension in the rat. Br J Pharmacol 115:945–952.
-
(1995)
Br J Pharmacol
, vol.115
, pp. 945-952
-
-
Hannon, J.P.1
Pfannkuche, H.J.2
Fozard, J.R.3
-
133
-
-
3042613515
-
A3 adenosine receptor agonist potentiates natural killer cell activity
-
Harish A, Hohana G, Fishman P, Arnon O, and Bar-Yehuda S (2003) A3 adenosine receptor agonist potentiates natural killer cell activity. Int J Oncol 23:1245–1249.
-
(2003)
Int J Oncol
, vol.23
, pp. 1245-1249
-
-
Harish, A.1
Hohana, G.2
Fishman, P.3
Arnon, O.4
Bar-Yehuda, S.5
-
134
-
-
0036135889
-
Effects of A(3) adenosine receptor activation and gene knock-out in ischemic-reperfused mouse heart
-
Harrison GJ, Cerniway RJ, Peart J, Berr SS, Ashton K, Regan S, Paul Matherne G, and Headrick JP (2002) Effects of A(3) adenosine receptor activation and gene knock-out in ischemic-reperfused mouse heart. Cardiovasc Res 53:147–155.
-
(2002)
Cardiovasc Res
, vol.53
, pp. 147-155
-
-
Harrison, G.J.1
Cerniway, R.J.2
Peart, J.3
Berr, S.S.4
Ashton, K.5
Regan, S.6
Paul Matherne, G.7
Headrick, J.P.8
-
135
-
-
0348222661
-
Adenosine: An endogenous regulator of innate immunity
-
Haskó G and Cronstein BN (2004) Adenosine: an endogenous regulator of innate immunity. Trends Immunol 25:33–39.
-
(2004)
Trends Immunol
, vol.25
, pp. 33-39
-
-
Haskó, G.1
Cronstein, B.N.2
-
136
-
-
84883698279
-
Regulation of inflammation by adenosine
-
Haskó G and Cronstein B (2013) Regulation of inflammation by adenosine. Front Immunol 4:85.
-
(2013)
Front Immunol
, vol.4
-
-
Haskó, G.1
Cronstein, B.2
-
137
-
-
51049101334
-
Adenosine receptors: Therapeutic aspects for inflammatory and immune diseases
-
Haskó G, Linden J, Cronstein B, and Pacher P (2008) Adenosine receptors: therapeutic aspects for inflammatory and immune diseases. Nat Rev Drug Discov 7: 759–770.
-
(2008)
Nat Rev Drug Discov
, vol.7
, pp. 759-770
-
-
Haskó, G.1
Linden, J.2
Cronstein, B.3
Pacher, P.4
-
138
-
-
0032500375
-
An agonist of adenosine A3 receptors decreases interleukin-12 and interferon-gamma production and prevents lethality in endotoxemic mice
-
Haskó G, Németh ZH, Vizi ES, Salzman AL, and Szabó C (1998) An agonist of adenosine A3 receptors decreases interleukin-12 and interferon-gamma production and prevents lethality in endotoxemic mice. Eur J Pharmacol 358:261–268.
-
(1998)
Eur J Pharmacol
, vol.358
, pp. 261-268
-
-
Haskó, G.1
Németh, Z.H.2
Vizi, E.S.3
Salzman, A.L.4
Szabó, C.5
-
140
-
-
0030588630
-
Adenosine receptor agonists differentially regulate IL-10, TNF-alpha, and nitric oxide production in RAW 264.7 macrophages and in endotoxemic mice
-
Haskó G, Szabó C, Németh ZH, Kvetan V, Pastores SM, and Vizi ES (1996) Adenosine receptor agonists differentially regulate IL-10, TNF-alpha, and nitric oxide production in RAW 264.7 macrophages and in endotoxemic mice. J Immunol 157: 4634–4640.
-
(1996)
J Immunol
, vol.157
, pp. 4634-4640
-
-
Haskó, G.1
Szabó, C.2
Németh, Z.H.3
Kvetan, V.4
Pastores, S.M.5
Vizi, E.S.6
-
141
-
-
19444363878
-
A3 adenosine receptor-mediated protection of the ischemic heart
-
Headrick JP and Peart J (2005) A3 adenosine receptor-mediated protection of the ischemic heart. Vascul Pharmacol 42:271–279.
-
(2005)
Vascul Pharmacol
, vol.42
, pp. 271-279
-
-
Headrick, J.P.1
Peart, J.2
-
142
-
-
64349085168
-
A series of 2,4-disubstituted quinolines as a new class of allosteric enhancers of the adenosine A3 receptor
-
Heitman LH, Göblyös A, Zweemer AM, Bakker R, Mulder-Krieger T, van Veldhoven JPD, de Vries H, Brussee J, and Ijzerman AP (2009) A series of 2,4-disubstituted quinolines as a new class of allosteric enhancers of the adenosine A3 receptor. J Med Chem 52:926–931.
-
(2009)
J Med Chem
, vol.52
, pp. 926-931
-
-
Heitman, L.H.1
Göblyös, A.2
Zweemer, A.M.3
Bakker, R.4
Mulder-Krieger, T.5
Van Veldhoven, J.6
De Vries, H.7
Brussee, J.8
Ijzerman, A.P.9
-
143
-
-
84895161057
-
Allosteric interactions at adenosine A(1) and A(3) receptors: New insights into the role of small molecules and receptor dimerization
-
Hill SJ, May LT, Kellam B, and Woolard J (2014) Allosteric interactions at adenosine A(1) and A(3) receptors: new insights into the role of small molecules and receptor dimerization. Br J Pharmacol 171:1102–1113.
-
(2014)
Br J Pharmacol
, vol.171
, pp. 1102-1113
-
-
Hill, S.J.1
May, L.T.2
Kellam, B.3
Woolard, J.4
-
144
-
-
84867399686
-
Adenosine A(3) receptorinduced proliferation of primary human coronary smooth muscle cells involving the induction of early growth response genes
-
Hinze AV, Mayer P, Harst A, and von Kügelgen I (2012) Adenosine A(3) receptorinduced proliferation of primary human coronary smooth muscle cells involving the induction of early growth response genes. J Mol Cell Cardiol 53:639–645.
-
(2012)
J Mol Cell Cardiol
, vol.53
, pp. 639-645
-
-
Hinze, A.V.1
Mayer, P.2
Harst, A.3
Von Kügelgen, I.4
-
145
-
-
34249809396
-
The protective effect of prior ischemia reperfusion adenosine A1 or A3 receptor activation in the normal and hypertrophied heart
-
Hochhauser E, Leshem D, Kaminski O, Cheporko Y, Vidne BA, and Shainberg A (2007) The protective effect of prior ischemia reperfusion adenosine A1 or A3 receptor activation in the normal and hypertrophied heart. Interact Cardiovasc Thorac Surg 6:363–368.
-
(2007)
Interact Cardiovasc Thorac Surg
, vol.6
, pp. 363-368
-
-
Hochhauser, E.1
Leshem, D.2
Kaminski, O.3
Cheporko, Y.4
Vidne, B.A.5
Shainberg, A.6
-
146
-
-
0041621598
-
Adenosine slows migration of dendritic cells but does not affect other aspects of dendritic cell maturation
-
Hofer S, Ivarsson L, Stoitzner P, Auffinger M, Rainer C, Romani N, and Heufler C (2003) Adenosine slows migration of dendritic cells but does not affect other aspects of dendritic cell maturation. J Invest Dermatol 121:300–307.
-
(2003)
J Invest Dermatol
, vol.121
, pp. 300-307
-
-
Hofer, S.1
Ivarsson, L.2
Stoitzner, P.3
Auffinger, M.4
Rainer, C.5
Romani, N.6
Heufler, C.7
-
147
-
-
84856487832
-
Expression of mRNA for adenosine A(1), A(2a), A(2b), and A(3) receptors in HL-60 cells: Dependence on cell cycle phases
-
Hofer M, Dušek L, Hoferová Z, Stixová L, and Pospíšil M (2011) Expression of mRNA for adenosine A(1), A(2a), A(2b), and A(3) receptors in HL-60 cells: dependence on cell cycle phases. Physiol Res 60:913–920.
-
(2011)
Physiol Res
, vol.60
, pp. 913-920
-
-
Hofer, M.1
Dušek, L.2
Hoferová, Z.3
Stixová, L.4
Pospíšil, M.5
-
148
-
-
0037140549
-
Adenosine acts through an A3 receptor to prevent the induction of murine anti-CD3-activated killer T cells
-
Hoskin DW, Butler JJ, Drapeau D, Haeryfar SM, and Blay J (2002) Adenosine acts through an A3 receptor to prevent the induction of murine anti-CD3-activated killer T cells. Int J Cancer 99:386–395.
-
(2002)
Int J Cancer
, vol.99
, pp. 386-395
-
-
Hoskin, D.W.1
Butler, J.J.2
Drapeau, D.3
Haeryfar, S.M.4
Blay, J.5
-
149
-
-
40249106427
-
Inhibition of T cell and natural killer cell function by adenosine and its contribution to immune evasion by tumor cells (Review)
-
Hoskin DW, Mader JS, Furlong SJ, Conrad DM, and Blay J (2008) Inhibition of T cell and natural killer cell function by adenosine and its contribution to immune evasion by tumor cells (Review). Int J Oncol 32:527–535.
-
(2008)
Int J Oncol
, vol.32
, pp. 527-535
-
-
Hoskin, D.W.1
Mader, J.S.2
Furlong, S.J.3
Conrad, D.M.4
Blay, J.5
-
150
-
-
0028600604
-
Adenosine as a possible inhibitor of killer T-cell activation in the microenvironment of solid tumours
-
Hoskin DW, Reynolds T, and Blay J (1994a) Adenosine as a possible inhibitor of killer T-cell activation in the microenvironment of solid tumours. Int J Cancer 59: 854–855.
-
(1994)
Int J Cancer
, vol.59
, pp. 854-855
-
-
Hoskin, D.W.1
Reynolds, T.2
Blay, J.3
-
151
-
-
0028062055
-
2-Chloroadenosine inhibits the MHCunrestricted cytolytic activity of anti-CD3-activated killer cells: Evidence for the involvement of a non-A1/A2 cell-surface adenosine receptor
-
Hoskin DW, Reynolds T, and Blay J (1994b) 2-Chloroadenosine inhibits the MHCunrestricted cytolytic activity of anti-CD3-activated killer cells: evidence for the involvement of a non-A1/A2 cell-surface adenosine receptor. Cell Immunol 159: 85–93.
-
(1994)
Cell Immunol
, vol.159
, pp. 85-93
-
-
Hoskin, D.W.1
Reynolds, T.2
Blay, J.3
-
152
-
-
77955848047
-
Stimulation of the P2X7 receptor kills rat retinal ganglion cells in vivo
-
Hu H, Lu W, Zhang M, Zhang X, Argall AJ, Patel S, Lee GE, Kim YC, Jacobson KA, and Laties AM, et al. (2010) Stimulation of the P2X7 receptor kills rat retinal ganglion cells in vivo. Exp Eye Res 91:425–432.
-
(2010)
Exp Eye Res
, vol.91
, pp. 425-432
-
-
Hu, H.1
Lu, W.2
Zhang, M.3
Zhang, X.4
Argall, A.J.5
Patel, S.6
Lee, G.E.7
Kim, Y.C.8
Jacobson, K.A.9
Laties, A.M.10
-
153
-
-
46049121127
-
Adenosine induces airway hyperresponsiveness through activation of A3 receptors on mast cells
-
Hua X, Chason KD, Fredholm BB, Deshpande DA, Penn RB, and Tilley SL (2008) Adenosine induces airway hyperresponsiveness through activation of A3 receptors on mast cells. J Allergy Clin Immunol 122:107–113, e1–e7.
-
(2008)
J Allergy Clin Immunol
, vol.122
-
-
Hua, X.1
Chason, K.D.2
Fredholm, B.B.3
Deshpande, D.A.4
Penn, R.B.5
Tilley, S.L.6
-
154
-
-
84898825468
-
Caspase inhibition via A3 adenosine receptors: A new cardioprotective mechanism against myocardial infarction
-
Hussain A, Gharanei AM, Nagra AS, and Maddock HL (2014) Caspase inhibition via A3 adenosine receptors: a new cardioprotective mechanism against myocardial infarction. Cardiovasc Drugs Ther 28:19–32.
-
(2014)
Cardiovasc Drugs Ther
, vol.28
, pp. 19-32
-
-
Hussain, A.1
Gharanei, A.M.2
Nagra, A.S.3
Maddock, H.L.4
-
155
-
-
0031593681
-
Adenosine A3 receptors: Novel ligands and paradoxical effects
-
Jacobson KA (1998) Adenosine A3 receptors: novel ligands and paradoxical effects. Trends Pharmacol Sci 19:184–191.
-
(1998)
Trends Pharmacol Sci
, vol.19
, pp. 184-191
-
-
Jacobson, K.A.1
-
156
-
-
78449310435
-
GPCR ligand-dendrimer (GLiDe) conjugates: Future smart drugs?
-
Jacobson KA (2010) GPCR ligand-dendrimer (GLiDe) conjugates: future smart drugs? Trends Pharmacol Sci 31:575–579.
-
(2010)
Trends Pharmacol Sci
, vol.31
, pp. 575-579
-
-
Jacobson, K.A.1
-
157
-
-
70349337301
-
Medicinal chemistry of the A3 adenosine receptor: Agonists, antagonists, and receptor engineering
-
1232159
-
Jacobson KA, Klutz AM, Tosh DK, Ivanov AA, Preti D, and Baraldi PG (2009) Medicinal chemistry of the A3 adenosine receptor: agonists, antagonists, and receptor engineering. Handb Exp Pharmacol 193:1232159.
-
(2009)
Handb Exp Pharmacol
, vol.193
-
-
Jacobson, K.A.1
Klutz, A.M.2
Tosh, D.K.3
Ivanov, A.A.4
Preti, D.5
Baraldi, P.G.6
-
158
-
-
84916236654
-
Methanocarba adenosine derivatives and dendrimer conjugated thereof
-
inventors, 20120264769. 2 Dec 2010
-
Jacobson KA and Melman A (2010), inventors. Methanocarba adenosine derivatives and dendrimer conjugated thereof. Patent 20120264769. 2 Dec 2010.
-
(2010)
Patent
-
-
Jacobson, K.A.1
Melman, A.2
-
159
-
-
0027333553
-
A role for central A3-adenosine receptors. Mediation of behavioral depressant effects
-
Jacobson KA, Nikodijević O, Shi D, Gallo-Rodriguez C, Olah ME, Stiles GL, and Daly JW (1993) A role for central A3-adenosine receptors. Mediation of behavioral depressant effects. FEBS Lett 336:57–60.
-
(1993)
FEBS Lett
, vol.336
, pp. 57-60
-
-
Jacobson, K.A.1
Nikodijević, O.2
Shi, D.3
Gallo-Rodriguez, C.4
Olah, M.E.5
Stiles, G.L.6
Daly, J.W.7
-
160
-
-
0030694505
-
Pharmacological characterization of novel A3 adenosine receptor-selective antagonists
-
Jacobson KA, Park KS, Jiang J-L, Kim YC, Olah ME, Stiles GL, and Ji X-D (1997) Pharmacological characterization of novel A3 adenosine receptor-selective antagonists. Neuropharmacology 36:1157–1165.
-
(1997)
Neuropharmacology
, vol.36
, pp. 1157-1165
-
-
Jacobson, K.A.1
Park, K.S.2
Jiang, J.-L.3
Kim, Y.C.4
Olah, M.E.5
Stiles, G.L.6
Ji, X.-D.7
-
161
-
-
0029057782
-
Structure-activity relationships of 9-alkyladenine and ribose-modified adenosine derivatives at rat A3 adenosine receptors
-
Jacobson KA, Siddiqi SM, Olah ME, Ji XD, Melman N, Bellamkonda K, Meshulam Y, Stiles GL, and Kim HO (1995) Structure-activity relationships of 9-alkyladenine and ribose-modified adenosine derivatives at rat A3 adenosine receptors. J Med Chem 38:1720–1735.
-
(1995)
J Med Chem
, vol.38
, pp. 1720-1735
-
-
Jacobson, K.A.1
Siddiqi, S.M.2
Olah, M.E.3
Ji, X.D.4
Melman, N.5
Bellamkonda, K.6
Meshulam, Y.7
Stiles, G.L.8
Kim, H.O.9
-
162
-
-
70350716433
-
Adenosine A(3) receptor suppresses prostate cancer metastasis by inhibiting NADPH oxidase activity
-
Jajoo S, Mukherjea D, Watabe K, and Ramkumar V (2009) Adenosine A(3) receptor suppresses prostate cancer metastasis by inhibiting NADPH oxidase activity. Neoplasia 11:1132–1145.
-
(2009)
Neoplasia
, vol.11
, pp. 1132-1145
-
-
Jajoo, S.1
Mukherjea, D.2
Watabe, K.3
Ramkumar, V.4
-
163
-
-
84918532342
-
A3 adenosine receptor agonist prevents the development of paclitaxelinduced neuropathic pain by modulating spinal glial-restricted redox-dependent signaling pathways
-
in press
-
Janes K, Esposito E, Doyle T, Cuzzocrea S, Tosh DK, Jacobson KA, and Salvemini D (2014a) A3 adenosine receptor agonist prevents the development of paclitaxelinduced neuropathic pain by modulating spinal glial-restricted redox-dependent signaling pathways. Pain, in press.
-
(2014)
Pain
-
-
Janes, K.1
Espositodoyle, E.2
Cuzzocrea, T.3
Jacobson, K.A.4
Salvemini, D.5
-
164
-
-
84918578946
-
Spinal neuroimmmune activation is independent of T-cell infiltration and attenuated by A3 adenosine receptor agonists in a model of oxaliplatin-induced peripheral neuropathy
-
in press
-
Janes K, Wahlman C, Little JW, Doyle T, Tosh DK, Jacobson KA, and Salvemini D (2014b) Spinal neuroimmmune activation is independent of T-cell infiltration and attenuated by A3 adenosine receptor agonists in a model of oxaliplatin-induced peripheral neuropathy. Brain Behav Immun, in press.
-
(2014)
Brain Behav Immun
-
-
Janes, K.1
Little, C.J.W.2
Doyle, T.3
Tosh, D.K.4
Jacobson, K.A.5
Salvemini, D.6
-
165
-
-
0043286709
-
N6-substituted D-49-thioadenosine-59-methyluronamides: Potent and selective agonists at the human A3 adenosine receptor
-
Jeong LS, Jin DZ, Kim HO, Shin DH, Moon HR, Gunaga P, Chun MW, Kim YC, Melman N, and Gao ZG, et al. (2003) N6-substituted D-49-thioadenosine-59-methyluronamides: potent and selective agonists at the human A3 adenosine receptor. J Med Chem 46:3775–3777.
-
(2003)
J Med Chem
, vol.46
, pp. 3775-3777
-
-
Jeong, L.S.1
Jin, D.Z.2
Kim, H.O.3
Shin, D.H.4
Moon, H.R.5
Gunaga, P.6
Chun, M.W.7
Kim, Y.C.8
Melman, N.9
Gao, Z.G.10
-
166
-
-
0030051539
-
Interactions of flavonoids and other phytochemicals with adenosine receptors
-
Ji XD, Melman N, and Jacobson KA (1996) Interactions of flavonoids and other phytochemicals with adenosine receptors. J Med Chem 39:781–788.
-
(1996)
J Med Chem
, vol.39
, pp. 781-788
-
-
Ji, X.D.1
Melman, N.2
Jacobson, K.A.3
-
167
-
-
0027943469
-
Species differences in ligand affinity at central A3-adenosine receptors
-
Ji XD, von Lubitz D, Olah ME, Stiles GL, and Jacobson KA (1994) Species differences in ligand affinity at central A3-adenosine receptors. Drug Dev Res 33:51–59.
-
(1994)
Drug Dev Res
, vol.33
, pp. 51-59
-
-
Ji, X.D.1
Von Lubitz, D.2
Olah, M.E.3
Stiles, G.L.4
Jacobson, K.A.5
-
168
-
-
10044283612
-
A(3) adenosine receptor deficiency does not influence atherogenesis
-
Jones MR, Zhao Z, Sullivan CP, Schreiber BM, Stone PJ, Toselli PA, Kagan HM, Cohen RA, and Ravid K (2004) A(3) adenosine receptor deficiency does not influence atherogenesis. J Cell Biochem 92:1034–1043.
-
(2004)
J Cell Biochem
, vol.92
, pp. 1034-1043
-
-
Jones, M.R.1
Zhao, Z.2
Sullivan, C.P.3
Schreiber, B.M.4
Stone, P.J.5
Toselli, P.A.6
Kagan, H.M.7
Cohen, R.A.8
Ravid, K.9
-
169
-
-
0032712049
-
A(3) adenosine receptor activation attenuates neutrophil function and neutrophil-mediated reperfusion injury
-
Jordan JE, Thourani VH, Auchampach JA, Robinson JA, Wang NP, and Vinten-Johansen J (1999) A(3) adenosine receptor activation attenuates neutrophil function and neutrophil-mediated reperfusion injury. Am J Physiol 277:H1895–H1905.
-
(1999)
Am J Physiol
, vol.277
, pp. H1895-H1905
-
-
Jordan, J.E.1
Thourani, V.H.2
Auchampach, J.A.3
Robinson, J.A.4
Wang, N.P.5
Vinten-Johansen, J.6
-
170
-
-
84859949262
-
Cordycepin as a sensitizer to tumour necrosis factor (TNF)-a-induced apoptosis through eukaryotic translation initiation factor 2a(eIF2a)- and mammalian target of rapamycin complex 1 (mTORC1)-mediated inhibition of nuclear factor (NF)-kB
-
Kadomatsu M, Nakajima S, Kato H, Gu L, Chi Y, Yao J, and Kitamura M (2012) Cordycepin as a sensitizer to tumour necrosis factor (TNF)-a-induced apoptosis through eukaryotic translation initiation factor 2a (eIF2a)- and mammalian target of rapamycin complex 1 (mTORC1)-mediated inhibition of nuclear factor (NF)-kB. Clin Exp Immunol 168:325–332.
-
(2012)
Clin Exp Immunol
, vol.168
, pp. 325-332
-
-
Kadomatsu, M.1
Nakajima, S.2
Kato, H.3
Gu, L.4
Chi, Y.5
Yao, J.6
Kitamura, M.7
-
171
-
-
84861358741
-
Apoptosisrelated gene transcription in human A549 lung cancer cells via A(3) adenosine receptor
-
Kamiya H, Kanno T, Fujita Y, Gotoh A, Nakano T, and Nishizaki T (2012) Apoptosisrelated gene transcription in human A549 lung cancer cells via A(3) adenosine receptor. Cell Physiol Biochem 29:687–696.
-
(2012)
Cell Physiol Biochem
, vol.29
, pp. 687-696
-
-
Kamiya, H.1
Kanno, T.2
Fujita, Y.3
Gotoh, A.4
Nakano, T.5
Nishizaki, T.6
-
172
-
-
84864408363
-
Adenosine induces apoptosis in SBC-3 human lung cancer cells through A(3) adenosine receptordependent AMID upregulation
-
Kanno T, Nakano T, Fujita Y, Gotoh A, and Nishizaki T (2012) Adenosine induces apoptosis in SBC-3 human lung cancer cells through A(3) adenosine receptordependent AMID upregulation. Cell Physiol Biochem 30:666–677.
-
(2012)
Cell Physiol Biochem
, vol.30
, pp. 666-677
-
-
Kanno, T.1
Nakano, T.2
Fujita, Y.3
Gotoh, A.4
Nishizaki, T.5
-
173
-
-
69649097791
-
7TM receptor allostery: Putting numbers to shapeshifting proteins
-
Kenakin TP (2009) 7TM receptor allostery: putting numbers to shapeshifting proteins. Trends Pharmacol Sci 30:460–469.
-
(2009)
Trends Pharmacol Sci
, vol.30
, pp. 460-469
-
-
Kenakin, T.P.1
-
174
-
-
84857497773
-
Biased signalling and allosteric machines: New vistas and challenges for drug discovery
-
Kenakin TP (2012) Biased signalling and allosteric machines: new vistas and challenges for drug discovery. Br J Pharmacol 165:1659–1669.
-
(2012)
Br J Pharmacol
, vol.165
, pp. 1659-1669
-
-
Kenakin, T.P.1
-
175
-
-
78149496159
-
Allosteric modulation of G proteincoupled receptors: A pharmacological perspective
-
Keov P, Sexton PM, and Christopoulos A (2011) Allosteric modulation of G proteincoupled receptors: a pharmacological perspective. Neuropharmacology 60:24–35.
-
(2011)
Neuropharmacology
, vol.60
, pp. 24-35
-
-
Keov, P.1
Sexton, P.M.2
Christopoulos, A.3
-
176
-
-
39749132227
-
Toward multivalent signaling across G protein-coupled receptors from poly(amidoamine) dendrimers
-
Kim Y, Hechler B, Klutz AM, Gachet C, and Jacobson KA (2008a) Toward multivalent signaling across G protein-coupled receptors from poly(amidoamine) dendrimers. Bioconjug Chem 19:406–411.
-
(2008)
Bioconjug Chem
, vol.19
, pp. 406-411
-
-
Kim, Y.1
Hechler, B.2
Klutz, A.M.3
Gachet, C.4
Jacobson, K.A.5
-
177
-
-
57449115129
-
Modulation of matrix metalloproteinase secretion by adenosine A3 receptor in preeclamptic villous explants
-
Kim YH, Hwang HS, Kim YT, Kim HS, and Park YW (2008b) Modulation of matrix metalloproteinase secretion by adenosine A3 receptor in preeclamptic villous explants. Reprod Sci 15:939–949.
-
(2008)
Reprod Sci
, vol.15
, pp. 939-949
-
-
Kim, Y.H.1
Hwang, H.S.2
Kim, Y.T.3
Kim, H.S.4
Park, Y.W.5
-
178
-
-
0029842517
-
Derivatives of the triazoloquinazoline adenosine antagonist (CGS15943) are selective for the human A3 receptor subtype
-
Kim YC, Ji XD, and Jacobson KA (1996) Derivatives of the triazoloquinazoline adenosine antagonist (CGS15943) are selective for the human A3 receptor subtype. J Med Chem 39:4142–4148.
-
(1996)
J Med Chem
, vol.39
, pp. 4142-4148
-
-
Kim, Y.C.1
Ji, X.D.2
Jacobson, K.A.3
-
179
-
-
0028171602
-
2-Substitution of N6-benzyladenosine-59-uronamides enhances selectivity for A3 adenosine receptors
-
Kim HO, Ji XD, Siddiqi SM, Olah ME, Stiles GL, and Jacobson KA (1994) 2-Substitution of N6-benzyladenosine-59-uronamides enhances selectivity for A3 adenosine receptors. J Med Chem 37:3614–3621.
-
(1994)
J Med Chem
, vol.37
, pp. 3614-3621
-
-
Kim, H.O.1
Ji, X.D.2
Siddiqi, S.M.3
Olah, M.E.4
Stiles, G.L.5
Jacobson, K.A.6
-
180
-
-
77955819668
-
A3 adenosine receptor antagonist, truncated Thio-Cl-IB-MECA, induces apoptosis in T24 human bladder cancer cells
-
Kim H, Kang JW, Lee S, Choi WJ, Jeong LS, Yang Y, Hong JT, and Yoon Y (2010) A3 adenosine receptor antagonist, truncated Thio-Cl-IB-MECA, induces apoptosis in T24 human bladder cancer cells. Anticancer Res 30:2823–2830.
-
(2010)
Anticancer Res
, vol.30
, pp. 2823-2830
-
-
Kim, H.1
Kang, J.W.2
Lee, S.3
Choi, W.J.4
Jeong, L.S.5
Yang, Y.6
Hong, J.T.7
Yoon, Y.8
-
181
-
-
84871455601
-
The adenosine A3 receptor agonist Cl-IBMECA induces cell death through Ca²⁺/ROS-dependent down regulation of ERK and Akt in A172 human glioma cells
-
Kim TH, Kim YK, and Woo JS (2012) The adenosine A3 receptor agonist Cl-IBMECA induces cell death through Ca²⁺/ROS-dependent down regulation of ERK and Akt in A172 human glioma cells. Neurochem Res 37:2667–2677.
-
(2012)
Neurochem Res
, vol.37
, pp. 2667-2677
-
-
Kim, T.H.1
Kim, Y.K.2
Woo, J.S.3
-
182
-
-
84880506278
-
Thio-Cl-IB-MECA, a novel A₃ adenosine receptor agonist, suppresses angiogenesis by regulating PI3K/AKT/mTOR and ERK signaling in endothelial cells
-
Kim GD, Oh J, Jeong LS, and Lee SK (2013) Thio-Cl-IB-MECA, a novel A₃ adenosine receptor agonist, suppresses angiogenesis by regulating PI3K/AKT/mTOR and ERK signaling in endothelial cells. Biochem Biophys Res Commun 437:79–86.
-
(2013)
Biochem Biophys Res Commun
, vol.437
, pp. 79-86
-
-
Kim, G.D.1
Oh, J.2
Jeong, L.S.3
Lee, S.K.4
-
183
-
-
33846116634
-
[3H]HEMADO—a novel tritiated agonist selective for the human adenosine A3 receptor
-
Klotz KN, Falgner N, Kachler S, Lambertucci C, Vittori S, Volpini R, and Cristalli G (2007) [3H]HEMADO—a novel tritiated agonist selective for the human adenosine A3 receptor. Eur J Pharmacol 556:14–18.
-
(2007)
Eur J Pharmacol
, vol.556
, pp. 14-18
-
-
Klotz, K.N.1
Falgner, N.2
Kachler, S.3
Lambertucci, C.4
Vittori, S.5
Volpini, R.6
Cristalli, G.7
-
184
-
-
77956631792
-
Aldehyde dehydrogenase activation prevents reperfusion arrhythmias by inhibiting local renin release from cardiac mast cells
-
Koda K, Salazar-Rodriguez M, Corti F, Chan NY, Estephan R, Silver RB, Mochly-Rosen D, and Levi R (2010) Aldehyde dehydrogenase activation prevents reperfusion arrhythmias by inhibiting local renin release from cardiac mast cells. Circulation 122:771–781.
-
(2010)
Circulation
, vol.122
, pp. 771-781
-
-
Koda, K.1
Salazar-Rodriguez, M.2
Corti, F.3
Chan, N.Y.4
Estephan, R.5
Silver, R.B.6
Mochly-Rosen, D.7
Levi, R.8
-
185
-
-
0029661826
-
Activation of A3 adenosine receptors on human eosinophils elevates intracellular calcium
-
Kohno Y, Ji X, Mawhorter SD, Koshiba M, and Jacobson KA (1996a) Activation of A3 adenosine receptors on human eosinophils elevates intracellular calcium. Blood 88: 3569–3574.
-
(1996)
Blood
, vol.88
, pp. 3569-3574
-
-
Kohno, Y.1
Ji, X.2
Mawhorter, S.D.3
Koshiba, M.4
Jacobson, K.A.5
-
186
-
-
0029871277
-
Induction of apoptosis in HL-60 human promyelocytic leukemia cells by adenosine A(3) receptor agonists
-
Kohno Y, Sei Y, Koshiba M, Kim HO, and Jacobson KA (1996b) Induction of apoptosis in HL-60 human promyelocytic leukemia cells by adenosine A(3) receptor agonists. Biochem Biophys Res Commun 219:904–910.
-
(1996)
Biochem Biophys Res Commun
, vol.219
, pp. 904-910
-
-
Kohno, Y.1
Sei, Y.2
Koshiba, M.3
Kim, H.O.4
Jacobson, K.A.5
-
188
-
-
33645115158
-
Adenosine inhibits tumor necrosis factor-arelease from mouse peritoneal macrophages via A2A and A2B but not the A3 adenosine receptor
-
Kreckler LM, Wan TC, Ge Z-D, and Auchampach JA (2006) Adenosine inhibits tumor necrosis factor-a release from mouse peritoneal macrophages via A2A and A2B but not the A3 adenosine receptor. J Pharmacol Exp Ther 317:172–180.
-
(2006)
J Pharmacol Exp Ther
, vol.317
, pp. 172-180
-
-
Kreckler, L.M.1
Wan, T.C.2
Ge, Z.-D.3
Auchampach, J.A.4
-
189
-
-
84877615153
-
Adenosine as an endogenous immunoregulator in cancer pathogenesis: Where to go?
-
Kumar V (2013) Adenosine as an endogenous immunoregulator in cancer pathogenesis: where to go? Purinergic Signal 9:145–165.
-
(2013)
Purinergic Signal
, vol.9
, pp. 145-165
-
-
Kumar, V.1
-
190
-
-
23844434887
-
G(i)-protein-dependent inhibition of IL-12 production is mediated by activation of the phosphatidylinositol 3-kinase-protein 3 kinase B/Akt pathway and JNK
-
la Sala A, Gadina M, and Kelsall BL (2005) G(i)-protein-dependent inhibition of IL-12 production is mediated by activation of the phosphatidylinositol 3-kinase-protein 3 kinase B/Akt pathway and JNK. J Immunol 175:2994–2999.
-
(2005)
J Immunol
, vol.175
, pp. 2994-2999
-
-
La Sala, A.1
Gadina, M.2
Kelsall, B.L.3
-
191
-
-
79960848582
-
Suppression of inflammation response by a novel Aadenosine receptor agonist thio-Cl-IB-MECA through inhibition of Akt and NF-kB signaling
-
Lee HS, Chung HJ, Lee HW, Jeong LS, and Lee SK (2011) Suppression of inflammation response by a novel A adenosine receptor agonist thio-Cl-IB-MECA through inhibition of Akt and NF-kB signaling. Immunobiology 216:997–1003.
-
(2011)
Immunobiology
, vol.216
, pp. 997-1003
-
-
Lee, H.S.1
Chung, H.J.2
Lee, H.W.3
Jeong, L.S.4
Lee, S.K.5
-
192
-
-
0034848312
-
A novel cardioprotective role of RhoA: New signaling mechanism for adenosine
-
Lee JE, Bokoch G, and Liang BT (2001) A novel cardioprotective role of RhoA: new signaling mechanism for adenosine. FASEB J 15:1886–1894.
-
(2001)
FASEB J
, vol.15
, pp. 1886-1894
-
-
Lee, J.E.1
Bokoch, G.2
Liang, B.T.3
-
193
-
-
32544439901
-
Activation of adenosine A3 receptor suppresses lipopolysaccharide-induced TNF-alpha production through inhibition of PI 3-kinase/Akt and NF-kappaB activation in murine BV2 microglial cells
-
Lee JY, Jhun BS, Oh YT, Lee JH, Choe W, Baik HH, Ha J, Yoon KS, Kim SS, and Kang I (2006a) Activation of adenosine A3 receptor suppresses lipopolysaccharide-induced TNF-alpha production through inhibition of PI 3-kinase/Akt and NF-kappaB activation in murine BV2 microglial cells. Neurosci Lett 396:1–6.
-
(2006)
Neurosci Lett
, vol.396
, pp. 1-6
-
-
Lee, J.Y.1
Jhun, B.S.2
Oh, Y.T.3
Lee, J.H.4
Choe, W.5
Baik, H.H.6
Ha, J.7
Yoon, K.S.8
Kim, S.S.9
Kang, I.10
-
194
-
-
33749357961
-
A3 adenosine receptor activation decreases mortality and renal and hepatic injury in murine septic peritonitis
-
Lee HT, Kim M, Joo JD, Gallos G, Chen JF, and Emala CW (2006b) A3 adenosine receptor activation decreases mortality and renal and hepatic injury in murine septic peritonitis. Am J Physiol Regul Integr Comp Physiol 291:R959–R969.
-
(2006)
Am J Physiol Regul Integr Comp Physiol
, vol.291
, pp. R959-R969
-
-
Lee, H.T.1
Kim, M.2
Joo, J.D.3
Gallos, G.4
Chen, J.F.5
Emala, C.W.6
-
195
-
-
78449276676
-
Adenosine A1 and A3 receptor agonists reduce hypoxic injury through the involvement of P38 MAPK
-
Leshem-Lev D, Hochhauser E, Chanyshev B, Isak A, and Shainberg A (2010) Adenosine A1 and A3 receptor agonists reduce hypoxic injury through the involvement of P38 MAPK. Mol Cell Biochem 345: 153–160.
-
(2010)
Mol Cell Biochem
, vol.345
, pp. 153-160
-
-
Leshem-Lev, D.1
Hochhauser, E.2
Chanyshev, B.3
Isak, A.4
Shainberg, A.5
-
196
-
-
84894633583
-
The role of activated adenosine receptors in degranulation of human LAD2 mast cells
-
Leung CT, Li A, Banerjee J, Gao ZG, Kambayashi T, Jacobson KA, and Civan MM (2014) The role of activated adenosine receptors in degranulation of human LAD2 mast cells. Purinergic Signal 10:465–475.
-
(2014)
Purinergic Signal
, vol.10
, pp. 465-475
-
-
Leung, C.T.1
Li, A.2
Banerjee, J.3
Gao, Z.G.4
Kambayashi, T.5
Jacobson, K.A.6
Civan, M.M.7
-
197
-
-
0032514382
-
Structure-activity relationships and molecular modeling of 3, 5-diacyl-2,4-dialkylpyridine derivatives as selective A3 adenosine receptor antagonists
-
Li AH, Moro S, Melman N, Ji XD, and Jacobson KA (1998) Structure-activity relationships and molecular modeling of 3, 5-diacyl-2,4-dialkylpyridine derivatives as selective A3 adenosine receptor antagonists. J Med Chem 41:3186–3201.
-
(1998)
J Med Chem
, vol.41
, pp. 3186-3201
-
-
Li, A.H.1
Moro, S.2
Melman, N.3
Ji, X.D.4
Jacobson, K.A.5
-
198
-
-
79952026098
-
Adenosine A3 receptors in muscle protection
-
Borea PA, Springer, New York
-
Liang BT, Urso M, Zambraski E, and Jacobson KA (2010) Adenosine A3 receptors in muscle protection, in A3 Adenosine Receptors from Cell Biology to Pharmacology and Therapeutics (Borea PA, ed) pp 257–280, Springer, New York.
-
(2010)
A3 Adenosine Receptors from Cell Biology to Pharmacology and Therapeutics
, pp. 257-280
-
-
Liang, B.T.1
Urso, M.2
Zambraski, E.3
Jacobson, K.A.4
-
199
-
-
0028169223
-
Cloned adenosine A3 receptors: Pharmacological properties, species differences and receptor functions
-
Linden J (1994) Cloned adenosine A3 receptors: pharmacological properties, species differences and receptor functions. Trends Pharmacol Sci 15:298–306.
-
(1994)
Trends Pharmacol Sci
, vol.15
, pp. 298-306
-
-
Linden, J.1
-
200
-
-
0027202159
-
Molecular cloning and functional expression of a sheep A3 adenosine receptor with widespread tissue distribution
-
Linden J, Taylor HE, Robeva AS, Tucker AL, Stehle JH, Rivkees SA, Fink JS, and Reppert SM (1993) Molecular cloning and functional expression of a sheep A3 adenosine receptor with widespread tissue distribution. Mol Pharmacol 44: 524–532.
-
(1993)
Mol Pharmacol
, vol.44
, pp. 524-532
-
-
Linden, J.1
Taylor, H.E.2
Robeva, A.S.3
Tucker, A.L.4
Stehle, J.H.5
Rivkees, S.A.6
Fink, J.S.7
Reppert, S.M.8
-
201
-
-
0028287617
-
Evidence that translocation of protein kinase C is a key event during ischemic preconditioning of rabbit myocardium
-
Liu Y, Ytrehus K, and Downey JM (1994) Evidence that translocation of protein kinase C is a key event during ischemic preconditioning of rabbit myocardium. J Mol Cell Cardiol 26:661–668.
-
(1994)
J Mol Cell Cardiol
, vol.26
, pp. 661-668
-
-
Liu, Y.1
Ytrehus, K.2
Downey, J.M.3
-
202
-
-
0141645291
-
Adenosine A3 receptors are located in neurons of the rat hippocampus
-
Lopes LV, Rebola N, Pinheiro PC, Richardson PJ, Oliveira CR, and Cunha RA (2003) Adenosine A3 receptors are located in neurons of the rat hippocampus. Neuroreport 14:1645–1648.
-
(2003)
Neuroreport
, vol.14
, pp. 1645-1648
-
-
Lopes, L.V.1
Rebola, N.2
Pinheiro, P.C.3
Richardson, P.J.4
Oliveira, C.R.5
Cunha, R.A.6
-
203
-
-
0141988684
-
An adenosine analogue, IB-MECA, downregulates estrogen receptor alpha and suppresses human breast cancer cell proliferation
-
Lu J, Pierron A, and Ravid K (2003) An adenosine analogue, IB-MECA, downregulates estrogen receptor alpha and suppresses human breast cancer cell proliferation. Cancer Res 63:6413–6423.
-
(2003)
Cancer Res
, vol.63
, pp. 6413-6423
-
-
Lu, J.1
Pierron, A.2
Ravid, K.3
-
204
-
-
0037453358
-
The adenosine A3 receptor agonist, N6-(3-iodobenzyl)-adenosine-59-Nmethyluronamide, is protective in two murine models of colitis
-
Mabley J, Soriano F, Pacher P, Haskó G, Marton A, Wallace R, Salzman A, and Szabó C (2003) The adenosine A3 receptor agonist, N6-(3-iodobenzyl)-adenosine-59-Nmethyluronamide, is protective in two murine models of colitis. Eur J Pharmacol 466:323–329.
-
(2003)
Eur J Pharmacol
, vol.466
, pp. 323-329
-
-
Mabley, J.1
Soriano, F.2
Pacher, P.3
Haskó, G.4
Marton, A.5
Wallace, R.6
Salzman, A.7
Szabó, C.8
-
205
-
-
0032529355
-
Protein kinase C and A3 adenosine receptor activation inhibit presynaptic metabotropic glutamate receptor (mGluR) function and uncouple mGluRs from GTP-binding proteins
-
Macek TA, Schaffhauser H, and Conn PJ (1998) Protein kinase C and A3 adenosine receptor activation inhibit presynaptic metabotropic glutamate receptor (mGluR) function and uncouple mGluRs from GTP-binding proteins. J Neurosci 18: 6138–6146.
-
(1998)
J Neurosci
, vol.18
, pp. 6138-6146
-
-
Macek, T.A.1
Schaffhauser, H.2
Conn, P.J.3
-
206
-
-
0037103340
-
Synthesis, biological properties, and molecular modeling investigation of the first potent, selective, and water-soluble human A(3) adenosine receptor antagonist
-
Maconi A, Pastorin G, Da Ros T, Spalluto G, Gao ZG, Jacobson KA, Baraldi PG, Cacciari B, Varani K, and Moro S, et al. (2002) Synthesis, biological properties, and molecular modeling investigation of the first potent, selective, and water-soluble human A(3) adenosine receptor antagonist. J Med Chem 45:3579–3582.
-
(2002)
J Med Chem
, vol.45
, pp. 3579-3582
-
-
Maconi, A.1
Pastorin, G.2
Da Ros, T.3
Spalluto, G.4
Gao, Z.G.5
Jacobson, K.A.6
Baraldi, P.G.7
Cacciari, B.8
Varani, K.9
Moro, S.10
-
207
-
-
0036784310
-
Adenosine A(3) receptor activation protects the myocardium from reperfusion/reoxygenation injury
-
Maddock HL, Mocanu MM, and Yellon DM (2002) Adenosine A(3) receptor activation protects the myocardium from reperfusion/reoxygenation injury. Am J Physiol Heart Circ Physiol 283:H1307–H1313.
-
(2002)
Am J Physiol Heart Circ Physiol
, vol.283
, pp. H1307-H1313
-
-
Maddock, H.L.1
Mocanu, M.M.2
Yellon, D.M.3
-
208
-
-
0142211261
-
A3 adenosine receptor activation in melanoma cells: Association between receptor fate and tumor growth inhibition
-
Madi L, Bar-Yehuda S, Barer F, Ardon E, Ochaion A, and Fishman P (2003) A3 adenosine receptor activation in melanoma cells: association between receptor fate and tumor growth inhibition. J Biol Chem 278:42121–42130.
-
(2003)
J Biol Chem
, vol.278
, pp. 42121-42130
-
-
Madi, L.1
Bar-Yehuda, S.2
Barer, F.3
Ardon, E.4
Ochaion, A.5
Fishman, P.6
-
209
-
-
33846246044
-
Overexpression of A3 adenosine receptor in peripheral blood mononuclear cells in rheumatoid arthritis: Involvement of nuclear factor-kappaB in mediating receptor level
-
Madi L, Cohen S, Ochayin A, Bar-Yehuda S, Barer F, and Fishman P (2007) Overexpression of A3 adenosine receptor in peripheral blood mononuclear cells in rheumatoid arthritis: involvement of nuclear factor-kappaB in mediating receptor level. J Rheumatol 34:20–26.
-
(2007)
J Rheumatol
, vol.34
, pp. 20-26
-
-
Madi, L.1
Cohen, S.2
Ochayin, A.3
Bar-Yehuda, S.4
Barer, F.5
Fishman, P.6
-
210
-
-
3042776794
-
The A3 adenosine receptor is highly expressed in tumor versus normal cells: Potential target for tumor growth inhibition
-
Madi L, Ochaion A, Rath-Wolfson L, Bar-Yehuda S, Erlanger A, Ohana G, Harish A, Merimski O, Barer F, and Fishman P (2004) The A3 adenosine receptor is highly expressed in tumor versus normal cells: potential target for tumor growth inhibition. Clin Cancer Res 10:4472–4479.
-
(2004)
Clin Cancer Res
, vol.10
, pp. 4472-4479
-
-
Madi, L.1
Ochaion, A.2
Rath-Wolfson, L.3
Bar-Yehuda, S.4
Erlanger, A.5
Ohana, G.6
Harish, A.7
Merimski, O.8
Barer, F.9
Fishman, P.10
-
211
-
-
84871711982
-
Enhancing pigmentation via activation of A3 adenosine receptors in B16 melanoma cells and in human skin explants
-
Madi L, Rosenberg-Haggen B, Nyska A, and Korenstein R (2013) Enhancing pigmentation via activation of A3 adenosine receptors in B16 melanoma cells and in human skin explants. Exp Dermatol 22:74–77.
-
(2013)
Exp Dermatol
, vol.22
, pp. 74-77
-
-
Madi, L.1
Rosenberg-Haggen, B.2
Nyska, A.3
Korenstein, R.4
-
212
-
-
29244490904
-
Activation of the adenosine A3 receptor in RAW 264.7 cells inhibits lipopolysaccharidestimulated tumor necrosis factor-alpha release by reducing calcium-dependent activation of nuclear factor-kappaB and extracellular signal-regulated kinase 1/2
-
Martin L, Pingle SC, Hallam DM, Rybak LP, and Ramkumar V (2006) Activation of the adenosine A3 receptor in RAW 264.7 cells inhibits lipopolysaccharidestimulated tumor necrosis factor-alpha release by reducing calcium-dependent activation of nuclear factor-kappaB and extracellular signal-regulated kinase 1/2. J Pharmacol Exp Ther 316:71–78.
-
(2006)
J Pharmacol Exp Ther
, vol.316
, pp. 71-78
-
-
Martin, L.1
Pingle, S.C.2
Hallam, D.M.3
Rybak, L.P.4
Ramkumar, V.5
-
213
-
-
33750483550
-
A3 adenosine receptors and mitogen-activated protein kinases in lung injury following in vivo reperfusion
-
Matot I, Weiniger CF, Zeira E, Galun E, Joshi BV, and Jacobson KA (2006) A3 adenosine receptors and mitogen-activated protein kinases in lung injury following in vivo reperfusion. Crit Care 10:R65.
-
(2006)
Crit Care
, vol.10
-
-
Matot, I.1
Weiniger, C.F.2
Zeira, E.3
Galun, E.4
Joshi, B.V.5
Jacobson, K.A.6
-
214
-
-
84856949873
-
Adenosine receptor-mediated cardioprotection: Are all 4 subtypes required or redundant?
-
McIntosh VJ and Lasley RD (2012) Adenosine receptor-mediated cardioprotection: are all 4 subtypes required or redundant? J Cardiovasc Pharmacol Ther 17:21–33.
-
(2012)
J Cardiovasc Pharmacol Ther
, vol.17
, pp. 21-33
-
-
McIntosh, V.J.1
Lasley, R.D.2
-
215
-
-
0030605935
-
Activation of adenosine A3 receptors on macrophages inhibits tumor necrosis factor-a
-
McWhinney CD, Dudley MW, Bowlin TL, Peet NP, Schook L, Bradshaw M, De M, Borcherding DR, and Edwards CK 3rd (1996) Activation of adenosine A3 receptors on macrophages inhibits tumor necrosis factor-a. Eur J Pharmacol 310:209–216. Melillo G (2004) HIF-1: a target for cancer, ischemia and inflammation—too good to be true? Cell Cycle 3:154–155.
-
(1996)
Eur J Pharmacol 310:209–216. Melillo G (2004) HIF-1: A Target for Cancer, Ischemia and inflammation—too Good to Be True? Cell Cycle
, vol.3
, pp. 154-155
-
-
McWhinney, C.D.1
Dudley, M.W.2
Bowlin, T.L.3
Peet, N.P.4
Schook, L.5
Bradshaw, M.6
De, M.7
Borcherding, D.R.8
Edwards, C.K.9
-
216
-
-
42949156868
-
Design of (N)-methanocarba adenosine 59-uronamides as speciesindependent A3 receptor-selective agonists
-
Melman A, Gao ZG, Kumar D, Wan TC, Gizewski E, Auchampach JA, and Jacobson KA (2008) Design of (N)-methanocarba adenosine 59-uronamides as speciesindependent A3 receptor-selective agonists. Bioorg Med Chem Lett 18:2813–2819.
-
(2008)
Bioorg Med Chem Lett
, vol.18
, pp. 2813-2819
-
-
Melman, A.1
Gao, Z.G.2
Kumar, D.3
Wan, T.C.4
Gizewski, E.5
Auchampach, J.A.6
Jacobson, K.A.7
-
217
-
-
77949275122
-
Dendrimer-based drug and imaging conjugates: Design considerations for nanomedical applications
-
Menjoge AR, Kannan RM, and Tomalia DA (2010) Dendrimer-based drug and imaging conjugates: design considerations for nanomedical applications. Drug Discov Today 15:171–185.
-
(2010)
Drug Discov Today
, vol.15
, pp. 171-185
-
-
Menjoge, A.R.1
Kannan, R.M.2
Tomalia, D.A.3
-
218
-
-
33644877968
-
A3 adenosine receptors modulate hypoxiainducible factor-1alpha expression in human A375 melanoma cells
-
Merighi S, Benini A, Mirandola P, Gessi S, Varani K, Leung E, MacLennan S, Baraldi PG, and Borea PA (2005a) A3 adenosine receptors modulate hypoxiainducible factor-1alpha expression in human A375 melanoma cells. Neoplasia 7: 894–903.
-
(2005)
Neoplasia
, vol.7
, pp. 894-903
-
-
Merighi, S.1
Benini, A.2
Mirandola, P.3
Gessi, S.4
Varani, K.5
Leung, E.6
Maclennan, S.7
Baraldi, P.G.8
Borea, P.A.9
-
219
-
-
34347206794
-
Hypoxia inhibits paclitaxel-induced apoptosis through adenosine-mediated phosphorylation of bad in glioblastoma cells
-
Merighi S, Benini A, Mirandola P, Gessi S, Varani K, Leung E, Maclennan S, Baraldi PG, and Borea PA (2007a) Hypoxia inhibits paclitaxel-induced apoptosis through adenosine-mediated phosphorylation of bad in glioblastoma cells. Mol Pharmacol 72:162–172.
-
(2007)
Mol Pharmacol
, vol.72
, pp. 162-172
-
-
Merighi, S.1
Benini, A.2
Mirandola, P.3
Gessi, S.4
Varani, K.5
Leung, E.6
Maclennan, S.7
Baraldi, P.G.8
Borea, P.A.9
-
220
-
-
21244447990
-
A3 adenosine receptor activation inhibits cell proliferation via phosphatidylinositol 3-kinase/Akt-dependent inhibition of the extracellular signal-regulated kinase 1/2 phosphorylation in A375 human melanoma cells
-
Merighi S, Benini A, Mirandola P, Gessi S, Varani K, Leung E, Maclennan S, and Borea PA (2005b) A3 adenosine receptor activation inhibits cell proliferation via phosphatidylinositol 3-kinase/Akt-dependent inhibition of the extracellular signal-regulated kinase 1/2 phosphorylation in A375 human melanoma cells. J Biol Chem 280:19516–19526.
-
(2005)
J Biol Chem
, vol.280
, pp. 19516-19526
-
-
Merighi, S.1
Benini, A.2
Mirandola, P.3
Gessi, S.4
Varani, K.5
Leung, E.6
Maclennan, S.7
Borea, P.A.8
-
221
-
-
33646909636
-
Adenosine modulates vascular endothelial growth factor expression via hypoxia-inducible factor-1 in human glioblastoma cells
-
Merighi S, Benini A, Mirandola P, Gessi S, Varani K, Leung E, Maclennan S, and Borea PA (2006) Adenosine modulates vascular endothelial growth factor expression via hypoxia-inducible factor-1 in human glioblastoma cells. Biochem Pharmacol 72:19–31.
-
(2006)
Biochem Pharmacol
, vol.72
, pp. 19-31
-
-
Merighi, S.1
Benini, A.2
Mirandola, P.3
Gessi, S.4
Varani, K.5
Leung, E.6
Maclennan, S.7
Borea, P.A.8
-
222
-
-
34547178922
-
Caffeine inhibits adenosine-induced accumulation of hypoxia-inducible factor-1alpha, vascular endothelial growth factor, and interleukin-8 expression in hypoxic human colon cancer cells
-
Merighi S, Benini A, Mirandola P, Gessi S, Varani K, Simioni C, Leung E, Maclennan S, Baraldi PG, and Borea PA (2007b) Caffeine inhibits adenosine-induced accumulation of hypoxia-inducible factor-1alpha, vascular endothelial growth factor, and interleukin-8 expression in hypoxic human colon cancer cells. Mol Pharmacol 72:395–406.
-
(2007)
Mol Pharmacol
, vol.72
, pp. 395-406
-
-
Merighi, S.1
Benini, A.2
Mirandola, P.3
Gessi, S.4
Varani, K.5
Simioni, C.6
Leung, E.7
Maclennan, S.8
Baraldi, P.G.9
Borea, P.A.10
-
223
-
-
0036428630
-
Adenosine receptors as mediators of both cell proliferation and cell death of cultured human melanoma cells
-
Merighi S, Mirandola P, Milani D, Varani K, Gessi S, Klotz KN, Leung E, Baraldi PG, and Borea PA (2002a) Adenosine receptors as mediators of both cell proliferation and cell death of cultured human melanoma cells. J Invest Dermatol 119:923–933.
-
(2002)
J Invest Dermatol
, vol.119
, pp. 923-933
-
-
Merighi, S.1
Mirandola, P.2
Milani, D.3
Varani, K.4
Gessi, S.5
Klotz, K.N.6
Leung, E.7
Baraldi, P.G.8
Borea, P.A.9
-
224
-
-
0141673290
-
A glance at adenosine receptors: Novel target for antitumor therapy
-
Merighi S, Mirandola P, Varani K, Gessi S, Leung E, Baraldi PG, Tabrizi MA, and Borea PA (2003) A glance at adenosine receptors: novel target for antitumor therapy. Pharmacol Ther 100:31–48.
-
(2003)
Pharmacol Ther
, vol.100
, pp. 31-48
-
-
Merighi, S.1
Mirandola, P.2
Varani, K.3
Gessi, S.4
Leung, E.5
Baraldi, P.G.6
Tabrizi, M.A.7
Borea, P.A.8
-
225
-
-
70249123905
-
A(2B) and A(3) adenosine receptors modulate vascular endothelial growth factor and interleukin-8 expression in human melanoma cells treated with etoposide and doxorubicin
-
Merighi S, Simioni C, Gessi S, Varani K, Mirandola P, Tabrizi MA, Baraldi PG, and Borea PA (2009) A(2B) and A(3) adenosine receptors modulate vascular endothelial growth factor and interleukin-8 expression in human melanoma cells treated with etoposide and doxorubicin. Neoplasia 11:1064–1073.
-
(2009)
Neoplasia
, vol.11
, pp. 1064-1073
-
-
Merighi, S.1
Simioni, C.2
Gessi, S.3
Varani, K.4
Mirandola, P.5
Tabrizi, M.A.6
Baraldi, P.G.7
Borea, P.A.8
-
226
-
-
84900241829
-
Regulation of second messenger systems and intracellular pathways
-
Borea PA, Springer, New York
-
Merighi S, Simioni C, Lane R, and IJzerman AP (2010) Regulation of second messenger systems and intracellular pathways, in A3 Adenosine Receptors from Cell Biology to Pharmacology and Therapeutics (Borea PA, ed) pp 257–280, Springer, New York.
-
(2010)
A3 Adenosine Receptors from Cell Biology to Pharmacology and Therapeutics
, pp. 257-280
-
-
Merighi, S.1
Simioni, C.2
Lane, R.3
Ijzerman, A.P.4
-
227
-
-
0035197079
-
Pharmacological and biochemical characterization of adenosine receptors in the human malignant melanoma A375 cell line
-
Merighi S, Varani K, Gessi S, Cattabriga E, Iannotta V, Ulouglu C, Leung E, and Borea PA (2001) Pharmacological and biochemical characterization of adenosine receptors in the human malignant melanoma A375 cell line. Br J Pharmacol 134:1215–1226.
-
(2001)
Br J Pharmacol
, vol.134
, pp. 1215-1226
-
-
Merighi, S.1
Varani, K.2
Gessi, S.3
Cattabriga, E.4
Iannotta, V.5
Ulouglu, C.6
Leung, E.7
Borea, P.A.8
-
228
-
-
0037081798
-
Binding thermodynamics at the human A(3) adenosine receptor
-
Merighi S, Varani K, Gessi S, Klotz K-N, Leung E, Baraldi PG, and Borea PA (2002b) Binding thermodynamics at the human A(3) adenosine receptor. Biochem Pharmacol 63:157–161.
-
(2002)
Biochem Pharmacol
, vol.63
, pp. 157-161
-
-
Merighi, S.1
Varani, K.2
Gessi, S.3
Klotz, K.-N.4
Leung, E.5
Baraldi, P.G.6
Borea, P.A.7
-
229
-
-
0025825121
-
Molecular cloning of a novel putative G-protein coupled receptor expressed during rat spermiogenesis
-
Meyerhof W, Müller-Brechlin R, and Richter D (1991) Molecular cloning of a novel putative G-protein coupled receptor expressed during rat spermiogenesis. FEBS Lett 284:155–160.
-
(1991)
FEBS Lett
, vol.284
, pp. 155-160
-
-
Meyerhof, W.1
Müller-Brechlin, R.2
Richter, D.3
-
230
-
-
0033088363
-
A3 adenosine receptors regulate Cl- channels of nonpigmented ciliary epithelial cells
-
Mitchell CH, Peterson-Yantorno K, Carré DA, McGlinn AM, Coca-Prados M, Stone RA, and Civan MM (1999) A3 adenosine receptors regulate Cl- channels of nonpigmented ciliary epithelial cells. Am J Physiol 276:C659–C666.
-
(1999)
Am J Physiol
, vol.276
, pp. C659-C666
-
-
Mitchell, C.H.1
Peterson-Yantorno, K.2
Carré, D.A.3
McGlinn, A.M.4
Coca-Prados, M.5
Stone, R.A.6
Civan, M.M.7
-
231
-
-
84866719355
-
Adoptive immunotherapy with Cl-IB-MECA-treated CD8+ T cells reduces melanoma growth in mice
-
Montinaro A, Forte G, Sorrentino R, Luciano A, Palma G, Arra C, Adcock IM, Pinto A, and Morello S (2012) Adoptive immunotherapy with Cl-IB-MECA-treated CD8+ T cells reduces melanoma growth in mice. PLoS ONE 7:e45401.
-
(2012)
Plos ONE
, vol.7
-
-
Montinaro, A.1
Forte, G.2
Sorrentino, R.3
Luciano, A.4
Palma, G.5
Arra, C.6
Adcock, I.M.7
Pinto, A.8
Morello, S.9
-
232
-
-
70149118604
-
Cl-IB-MECA enhances TRAIL-induced apoptosis via the modulation of NF-kappaB signalling pathway in thyroid cancer cells
-
Morello S, Sorrentino R, Porta A, Forte G, Popolo A, Petrella A, and Pinto A (2009) Cl-IB-MECA enhances TRAIL-induced apoptosis via the modulation of NF-kappaB signalling pathway in thyroid cancer cells. J Cell Physiol 221:378–386.
-
(2009)
J Cell Physiol
, vol.221
, pp. 378-386
-
-
Morello, S.1
Sorrentino, R.2
Porta, A.3
Forte, G.4
Popolo, A.5
Petrella, A.6
Pinto, A.7
-
233
-
-
57349127258
-
A3 adenosine receptor signaling influences pulmonary inflammation and fibrosis
-
Morschl E, Molina JG, Volmer JB, Mohsenin A, Pero RS, Hong JS, Kheradmand F, Lee JJ, and Blackburn MR (2008) A3 adenosine receptor signaling influences pulmonary inflammation and fibrosis. Am J Respir Cell Mol Biol 39:697–705.
-
(2008)
Am J Respir Cell Mol Biol
, vol.39
, pp. 697-705
-
-
Morschl, E.1
Molina, J.G.2
Volmer, J.B.3
Mohsenin, A.4
Pero, R.S.5
Hong, J.S.6
Kheradmand, F.7
Lee, J.J.8
Blackburn, M.R.9
-
234
-
-
1442314696
-
Role of direct RhoAphospholipase D1 interaction in mediating adenosine-induced protection from cardiac ischemia
-
Mozzicato S, Joshi BV, Jacobson KA, and Liang BT (2004) Role of direct RhoAphospholipase D1 interaction in mediating adenosine-induced protection from cardiac ischemia. FASEB J 18:406–408.
-
(2004)
FASEB J
, vol.18
, pp. 406-408
-
-
Mozzicato, S.1
Joshi, B.V.2
Jacobson, K.A.3
Liang, B.T.4
-
235
-
-
0036682414
-
Imidazo[2,1-i]purin-5-ones and related tricyclic water-soluble purine derivatives: Potent A(2A)- and A(3)-adenosine receptor antagonists
-
Müller CE, Thorand M, Qurishi R, Diekmann M, Jacobson KA, Padgett WL, and Daly JW (2002) Imidazo[2,1-i]purin-5-ones and related tricyclic water-soluble purine derivatives: potent A(2A)- and A(3)-adenosine receptor antagonists. J Med Chem 45: 3440–3450.
-
(2002)
J Med Chem
, vol.45
, pp. 3440-3450
-
-
Müller, C.E.1
Thorand, M.2
Qurishi, R.3
Diekmann, M.4
Jacobson, K.A.5
Padgett, W.L.6
Daly, J.W.7
-
236
-
-
84876689863
-
Adenosine A3 receptor activation attenuates lung ischemia-reperfusion injury
-
Mulloy DP, Sharma AK, Fernandez LG, Zhao Y, Lau CL, Kron IL, and Laubach VE (2013) Adenosine A3 receptor activation attenuates lung ischemia-reperfusion injury. Ann Thorac Surg 95:1762–1767.
-
(2013)
Ann Thorac Surg
, vol.95
, pp. 1762-1767
-
-
Mulloy, D.P.1
Sharma, A.K.2
Fernandez, L.G.3
Zhao, Y.4
Lau, C.L.5
Kron, I.L.6
Laubach, V.E.7
-
237
-
-
0342716464
-
Cloning and characterisation of the human adenosine A3 receptor gene
-
Murrison EM, Goodson SJ, Edbrooke MR, and Harris CA (1996) Cloning and characterisation of the human adenosine A3 receptor gene. FEBS Lett 384:243–246.
-
(1996)
FEBS Lett
, vol.384
, pp. 243-246
-
-
Murrison, E.M.1
Goodson, S.J.2
Edbrooke, M.R.3
Harris, C.A.4
-
238
-
-
84870920414
-
A3 adenosine receptor mediates apoptosis in in vitro RCC4-VHL human renal cancer cells by up-regulating AMID expression
-
Nagaya H, Gotoh A, Kanno T, and Nishizaki T (2013) A3 adenosine receptor mediates apoptosis in in vitro RCC4-VHL human renal cancer cells by up-regulating AMID expression. J Urol 189:321–328.
-
(2013)
J Urol
, vol.189
, pp. 321-328
-
-
Nagaya, H.1
Gotoh, A.2
Kanno, T.3
Nishizaki, T.4
-
239
-
-
32144458105
-
Antitumor effect of cordycepin (39-deoxyadenosine) on mouse melanoma and lung carcinoma cells involves adenosine A3 receptor stimulation
-
Nakamura K, Yoshikawa N, Yamaguchi Y, Kagota S, Shinozuka K, and Kunitomo M (2006) Antitumor effect of cordycepin (39-deoxyadenosine) on mouse melanoma and lung carcinoma cells involves adenosine A3 receptor stimulation. Anticancer Res 26 (1A):43–47.
-
(2006)
Anticancer Res
, vol.26
, Issue.1A
, pp. 43-47
-
-
Nakamura, K.1
Yoshikawa, N.2
Yamaguchi, Y.3
Kagota, S.4
Shinozuka, K.5
Kunitomo, M.6
-
240
-
-
84896822622
-
Synthesis and anti-renal fibrosis activity of conformationally locked truncated 2-hexynyl-N(6)-substituted-(N)-methanocarba-nucleosides as A3 adenosine receptor antagonists and partial agonists
-
Nayak A, Chandra G, Hwang I, Kim K, Hou X, Kim HO, Sahu PK, Roy KK, Yoo J, and Lee Y, et al. (2014) Synthesis and anti-renal fibrosis activity of conformationally locked truncated 2-hexynyl-N(6)-substituted-(N)-methanocarba-nucleosides as A3 adenosine receptor antagonists and partial agonists. J Med Chem 57: 1344–1354.
-
(2014)
J Med Chem
, vol.57
, pp. 1344-1354
-
-
Nayak, A.1
Chandra, G.2
Hwang, I.3
Kim, K.4
Hou, X.5
Kim, H.O.6
Sahu, P.K.7
Roy, K.K.8
Yoo, J.9
Lee, Y.10
-
241
-
-
0032548768
-
Mitogenic signaling from P1 and P2 purinergic receptors to mitogen-activated protein kinase in human fetal astrocyte cultures
-
Neary JT, McCarthy M, Kang Y, and Zuniga S (1998) Mitogenic signaling from P1 and P2 purinergic receptors to mitogen-activated protein kinase in human fetal astrocyte cultures. Neurosci Lett 242:159–162.
-
(1998)
Neurosci Lett
, vol.242
, pp. 159-162
-
-
Neary, J.T.1
McCarthy, M.2
Kang, Y.3
Zuniga, S.4
-
243
-
-
84863469859
-
AMP converted from intracellularly transported adenosine upregulates p53 expression to induce malignant pleural mesothelioma cell apoptosis
-
Nogi Y, Kanno T, Nakano T, Fujita Y, Tabata C, Fukuoka K, Gotoh A, and Nishizaki T (2012) AMP converted from intracellularly transported adenosine upregulates p53 expression to induce malignant pleural mesothelioma cell apoptosis. Cell Physiol Biochem 30:61–74.
-
(2012)
Cell Physiol Biochem
, vol.30
, pp. 61-74
-
-
Nogi, Y.1
Kanno, T.2
Nakano, T.3
Fujita, Y.4
Tabata, C.5
Fukuoka, K.6
Gotoh, A.7
Nishizaki, T.8
-
244
-
-
48349143486
-
The A3 adenosine receptor agonist CF502 inhibits the PI3K, PKB/Akt and NF-kappaB signaling pathway in synoviocytes from rheumatoid arthritis patients and in adjuvant-induced arthritis rats
-
Ochaion A, Bar-Yehuda S, Cohen S, Amital H, Jacobson KA, Joshi BV, Gao ZG, Barer F, Patoka R, and Del Valle L, et al. (2008) The A3 adenosine receptor agonist CF502 inhibits the PI3K, PKB/Akt and NF-kappaB signaling pathway in synoviocytes from rheumatoid arthritis patients and in adjuvant-induced arthritis rats. Biochem Pharmacol 76:482–494.
-
(2008)
Biochem Pharmacol
, vol.76
, pp. 482-494
-
-
Ochaion, A.1
Bar-Yehuda, S.2
Cohen, S.3
Amital, H.4
Jacobson, K.A.5
Joshi, B.V.6
Gao, Z.G.7
Barer, F.8
Patoka, R.9
Del Valle, L.10
-
245
-
-
67649385777
-
The anti-inflammatory target A(3) adenosine receptor is over-expressed in rheumatoid arthritis, psoriasis and Crohn’s disease
-
Ochaion A, Bar-Yehuda S, Cohen S, Barer F, Patoka R, Amital H, Reitblat T, Reitblat A, Ophir J, and Konfino I, et al. (2009) The anti-inflammatory target A(3) adenosine receptor is over-expressed in rheumatoid arthritis, psoriasis and Crohn’s disease. Cell Immunol 258:115–122.
-
(2009)
Cell Immunol
, vol.258
, pp. 115-122
-
-
Ochaion, A.1
Bar-Yehuda, S.2
Cohen, S.3
Barer, F.4
Patoka, R.5
Amital, H.6
Reitblat, T.7
Reitblat, A.8
Ophir, J.9
Konfino, I.10
-
246
-
-
84859635614
-
Adenosine A3 receptor is involved in ADP-induced microglial process extension and migration
-
Ohsawa K, Sanagi T, Nakamura Y, Suzuki E, Inoue K, and Kohsaka S (2012) Adenosine A3 receptor is involved in ADP-induced microglial process extension and migration. J Neurochem 121:217–227.
-
(2012)
J Neurochem
, vol.121
, pp. 217-227
-
-
Ohsawa, K.1
Sanagi, T.2
Nakamura, Y.3
Suzuki, E.4
Inoue, K.5
Kohsaka, S.6
-
247
-
-
0037103354
-
Fujiwara H, and Nagao Y (2002) 1,2,4-Triazolo[5,1-i]purine derivatives as highly potent and selective human adenosine A(3) receptor ligands
-
Okamura T, Kurogi Y, Nishikawa H, Hashimoto K, Fujiwara H, and Nagao Y (2002) 1,2,4-Triazolo[5,1-i]purine derivatives as highly potent and selective human adenosine A(3) receptor ligands. J Med Chem 45:3703–3708.
-
J Med Chem
, vol.45
, pp. 3703-3708
-
-
Okamura, T.1
Kurogi, Y.2
Nishikawa, H.3
Hashimoto, K.4
-
248
-
-
0028179205
-
Jacobson KA, and Stiles GL (1994) [125I]AB-MECA, a high affinity radioligand for the rat A3 adenosine receptor
-
Olah ME, Gallo-Rodriguez C, Jacobson KA, and Stiles GL (1994) [125I]AB-MECA, a high affinity radioligand for the rat A3 adenosine receptor. Mol Pharmacol 45: 978–982.
-
Mol Pharmacol
, vol.45
, pp. 978-982
-
-
Olah, M.E.1
Gallo-Rodriguez, C.2
-
249
-
-
84857472460
-
Electromagnetic fields (EMFs) and adenosine receptors modulate prostaglandin E(2) and cytokine release in human osteoarthritic synovial fibroblasts
-
Ongaro A, Varani K, Masieri FF, Pellati A, Massari L, Cadossi R, Vincenzi F, Borea PA, Fini M, and Caruso A, et al. (2012) Electromagnetic fields (EMFs) and adenosine receptors modulate prostaglandin E(2) and cytokine release in human osteoarthritic synovial fibroblasts. J Cell Physiol 227:2461–2469.
-
(2012)
J Cell Physiol
, vol.227
, pp. 2461-2469
-
-
Ongaro, A.1
Varani, K.2
Masieri, F.F.3
Pellati, A.4
Massari, L.5
Cadossi, R.6
Vincenzi, F.7
Borea, P.A.8
Fini, M.9
Caruso, A.10
-
250
-
-
84863459465
-
A3 adenosine receptor-mediated p53-dependent apoptosis in Lu-65 human lung cancer cells
-
Otsuki T, Kanno T, Fujita Y, Tabata C, Fukuoka K, Nakano T, Gotoh A, and Nishizaki T (2012) A3 adenosine receptor-mediated p53-dependent apoptosis in Lu-65 human lung cancer cells. Cell Physiol Biochem 30:210–220.
-
(2012)
Cell Physiol Biochem
, vol.30
, pp. 210-220
-
-
Otsuki, T.1
Kanno, T.2
Fujita, Y.3
Tabata, C.4
Fukuoka, K.5
Nakano, T.6
Gotoh, A.7
Nishizaki, T.8
-
251
-
-
0037295346
-
Jacobson KA, and Müller CE (2003) 2-Phenylimidazo[2,1-i]purin-5-ones: Structure-activity relationships and characterization of potent and selective inverse agonists at Human A3 adenosine receptors
-
Ozola V, Thorand M, Diekmann M, Qurishi R, Schumacher B, Jacobson KA, and Müller CE (2003) 2-Phenylimidazo[2,1-i]purin-5-ones: structure-activity relationships and characterization of potent and selective inverse agonists at Human A3 adenosine receptors. Bioorg Med Chem 11:347–356.
-
Bioorg Med Chem
, vol.11
, pp. 347-356
-
-
Ozola, V.1
Thorand, M.2
Diekmann, M.3
Qurishi, R.4
Schumacher, B.5
-
252
-
-
0028818439
-
Agonist-dependent phosphorylation and desensitization of the rat A3 adenosine receptor. Evidence for a G-proteincoupled receptor kinase-mediated mechanism
-
Palmer TM, Benovic JL, and Stiles GL (1995) Agonist-dependent phosphorylation and desensitization of the rat A3 adenosine receptor. Evidence for a G-proteincoupled receptor kinase-mediated mechanism. J Biol Chem 270:29607–29613.
-
(1995)
J Biol Chem
, vol.270
, pp. 29607-29613
-
-
Palmer, T.M.1
Benovic, J.L.2
Stiles, G.L.3
-
253
-
-
0034006037
-
Identification of threonine residues controlling the agonist-dependent phosphorylation and desensitization of the rat A(3) adenosine receptor
-
Palmer TM and Stiles GL (2000) Identification of threonine residues controlling the agonist-dependent phosphorylation and desensitization of the rat A(3) adenosine receptor. Mol Pharmacol 57:539–545.
-
(2000)
Mol Pharmacol
, vol.57
, pp. 539-545
-
-
Palmer, T.M.1
Stiles, G.L.2
-
254
-
-
2442450703
-
An adenosine analog (IB-MECA) inhibits anchorage-dependent cell growth of various human breast cancer cell lines
-
Panjehpour M and Karami-Tehrani F (2004) An adenosine analog (IB-MECA) inhibits anchorage-dependent cell growth of various human breast cancer cell lines. Int J Biochem Cell Biol 36:1502–1509.
-
(2004)
Int J Biochem Cell Biol
, vol.36
, pp. 1502-1509
-
-
Panjehpour, M.1
Karami-Tehrani, F.2
-
255
-
-
0034848771
-
IdzkoM, Herouy Y, Rheinen H, Gebicke-Haerter PJ, Mrowietz U, Dichmann S, and Norgauer J
-
Panther E, IdzkoM, Herouy Y, Rheinen H, Gebicke-Haerter PJ, Mrowietz U, Dichmann S, and Norgauer J (2001) Expression and function of adenosine receptors in human dendritic cells. FASEB J 15:1963–1970.
-
(2001)
Expression and Function of Adenosine Receptors in Human Dendritic Cells. FASEB J
, vol.15
, pp. 1963-1970
-
-
Panther, E.1
-
256
-
-
84880866056
-
Rational design of sulfonated A3 adenosine receptor-selective nucleosides as pharmacological tools to study chronic neuropathic pain
-
Paoletta S, Tosh DK, Finley A, Gizewski ET, Moss SM, Gao ZG, Auchampach JA, Salvemini D, and Jacobson KA (2013) Rational design of sulfonated A3 adenosine receptor-selective nucleosides as pharmacological tools to study chronic neuropathic pain. J Med Chem 56:5949–5963.
-
(2013)
J Med Chem
, vol.56
, pp. 5949-5963
-
-
Paoletta, S.1
Tosh, D.K.2
Finley, A.3
Gizewski, E.T.4
Moss, S.M.5
Gao, Z.G.6
Auchampach, J.A.7
Salvemini, D.8
Jacobson, K.A.9
-
257
-
-
34147175541
-
Adenosinergic cardioprotection: Multiple receptors, multiple pathways
-
Peart JN and Headrick JP (2007) Adenosinergic cardioprotection: multiple receptors, multiple pathways. Pharmacol Ther 114:208–221.
-
(2007)
Pharmacol Ther
, vol.114
, pp. 208-221
-
-
Peart, J.N.1
Headrick, J.P.2
-
258
-
-
34447645146
-
Role of adenosine A3 receptors on CA1 hippocampal neurotransmission during oxygen-glucose deprivation episodes of different duration
-
Pugliese AM, Coppi E, Volpini R, Cristalli G, Corradetti R, Jeong LS, Jacobson KA, and Pedata F (2007) Role of adenosine A3 receptors on CA1 hippocampal neurotransmission during oxygen-glucose deprivation episodes of different duration. Biochem Pharmacol 74:768–779.
-
(2007)
Biochem Pharmacol
, vol.74
, pp. 768-779
-
-
Pugliese, A.M.1
Coppi, E.2
Volpini, R.3
Cristalli, G.4
Corradetti, R.5
Jeong, L.S.6
Jacobson, K.A.7
Pedata, F.8
-
259
-
-
0141992197
-
Brief, repeated, oxygen-glucose deprivation episodes protect neurotransmission from a longer ischemic episode in the in vitro hippocampus: Role of adenosine receptors
-
Pugliese AM, Latini S, Corradetti R, and Pedata F (2003) Brief, repeated, oxygen-glucose deprivation episodes protect neurotransmission from a longer ischemic episode in the in vitro hippocampus: role of adenosine receptors. Br J Pharmacol 140:305–314.
-
(2003)
Br J Pharmacol
, vol.140
, pp. 305-314
-
-
Pugliese, A.M.1
Latini, S.2
Corradetti, R.3
Pedata, F.4
-
260
-
-
0031754497
-
Receptors for purines and pyrimidines
-
Ralevic V and Burnstock G (1998) Receptors for purines and pyrimidines. Pharmacol Rev 50:413–492.
-
(1998)
Pharmacol Rev
, vol.50
, pp. 413-492
-
-
Ralevic, V.1
Burnstock, G.2
-
261
-
-
0027337474
-
The A3 adenosine receptor is the unique adenosine receptor which facilitates release of allergic mediators in mast cells
-
Ramkumar V, Stiles GL, Beaven MA, and Ali H (1993) The A3 adenosine receptor is the unique adenosine receptor which facilitates release of allergic mediators in mast cells. J Biol Chem 268:16887–16890.
-
(1993)
J Biol Chem
, vol.268
, pp. 16887-16890
-
-
Ramkumar, V.1
Stiles, G.L.2
Beaven, M.A.3
Ali, H.4
-
262
-
-
25444513372
-
Gs protein-coupled adenosine receptor signaling and lytic function of activated NK cells
-
Raskovalova T, Huang X, Sitkovsky M, Zacharia LC, Jackson EK, and Gorelik E (2005) Gs protein-coupled adenosine receptor signaling and lytic function of activated NK cells. J Immunol 175:4383–4391.
-
(2005)
J Immunol
, vol.175
, pp. 4383-4391
-
-
Raskovalova, T.1
Huang, X.2
Sitkovsky, M.3
Zacharia, L.C.4
Jackson, E.K.5
Gorelik, E.6
-
263
-
-
80051658642
-
Crystal structure of the b2 adrenergic receptor-Gs protein complex
-
Rasmussen SG, DeVree BT, Zou Y, Kruse AC, Chung KY, Kobilka TS, Thian FS, Chae PS, Pardon E, and Calinski D, et al. (2011) Crystal structure of the b2 adrenergic receptor-Gs protein complex. Nature 477:549–555.
-
(2011)
Nature
, vol.477
, pp. 549-555
-
-
Rasmussen, S.G.1
Devree, B.T.2
Zou, Y.3
Kruse, A.C.4
Chung, K.Y.5
Kobilka, T.S.6
Thian, F.S.7
Chae, P.S.8
Pardon, E.9
Calinski, D.10
-
264
-
-
33748518875
-
IB-MECA, an A3 adenosine receptor agonist prevents bone resorption in rats with adjuvant induced arthritis
-
Rath-Wolfson L, Bar-Yehuda S, Madi L, Ochaion A, Cohen S, Zabutti A, and Fishman P (2006) IB-MECA, an A3 adenosine receptor agonist prevents bone resorption in rats with adjuvant induced arthritis. Clin Exp Rheumatol 24:400–406.
-
(2006)
Clin Exp Rheumatol
, vol.24
, pp. 400-406
-
-
Rath-Wolfson, L.1
Bar-Yehuda, S.2
Madi, L.3
Ochaion, A.4
Cohen, S.5
Zabutti, A.6
Fishman, P.7
-
265
-
-
22044454590
-
Different roles of adenosine A1, A2A and A3 receptors in controlling kainate-induced toxicity in cortical cultured neurons
-
Rebola N, Rodrigues RJ, Oliveira CR, and Cunha RA (2005) Different roles of adenosine A1, A2A and A3 receptors in controlling kainate-induced toxicity in cortical cultured neurons. Neurochem Int 47:317–325.
-
(2005)
Neurochem Int
, vol.47
, pp. 317-325
-
-
Rebola, N.1
Rodrigues, R.J.2
Oliveira, C.R.3
Cunha, R.A.4
-
266
-
-
0034493319
-
Studies on the effects of adenosine A3 receptor stimulation on human eosinophils isolated from non-asthmatic or asthmatic donors
-
Reeves JJ, Harris CA, Hayes BP, Butchers PR, and Sheehan MJ (2000) Studies on the effects of adenosine A3 receptor stimulation on human eosinophils isolated from non-asthmatic or asthmatic donors. Inflamm Res 49:666–672.
-
(2000)
Inflamm Res
, vol.49
, pp. 666-672
-
-
Reeves, J.J.1
Harris, C.A.2
Hayes, B.P.3
Butchers, P.R.4
Sheehan, M.J.5
-
267
-
-
0030611258
-
Adenosine A3 receptors promote degranulation of rat mast cells both in vitro and in vivo
-
Reeves JJ, Jones CA, Sheehan MJ, Vardey CJ, and Whelan CJ (1997) Adenosine A3 receptors promote degranulation of rat mast cells both in vitro and in vivo. Inflamm Res 46:180–184.
-
(1997)
Inflamm Res
, vol.46
, pp. 180-184
-
-
Reeves, J.J.1
Jones, C.A.2
Sheehan, M.J.3
Vardey, C.J.4
Whelan, C.J.5
-
269
-
-
79960248344
-
Impact of disrupting adenosine A₃receptors (A₃⁻/⁻AR) on colonic motility or progression of colitis in the mouse
-
Ren T, Grants I, Alhaj M, McKiernan M, Jacobson M, Hassanain HH, Frankel W, Wunderlich J, and Christofi FL (2011) Impact of disrupting adenosine A₃ receptors (A₃⁻/⁻AR) on colonic motility or progression of colitis in the mouse. Inflamm Bowel Dis 17:1698–1713.
-
(2011)
Inflamm Bowel Dis
, vol.17
, pp. 1698-1713
-
-
Ren, T.1
Grants, I.2
Alhaj, M.3
McKiernan, M.4
Jacobson, M.5
Hassanain, H.H.6
Frankel, W.7
Wunderlich, J.8
Christofi, F.L.9
-
270
-
-
0034669372
-
Activation of A(3) adenosine receptor induces calcium entry and chloride secretion in A(6) cells
-
Reshkin SJ, Guerra L, Bagorda A, Debellis L, Cardone R, Li AH, Jacobson KA, and Casavola V (2000) Activation of A(3) adenosine receptor induces calcium entry and chloride secretion in A(6) cells. J Membr Biol 178:103–113.
-
(2000)
J Membr Biol
, vol.178
, pp. 103-113
-
-
Reshkin, S.J.1
Guerra, L.2
Bagorda, A.3
Debellis, L.4
Cardone, R.5
Li, A.H.6
Jacobson, K.A.7
Casavola, V.8
-
271
-
-
0021162425
-
Enhancement of tetrodotoxin-induced axonal blockade by adenosine, adenosine analogues, dibutyryl cyclic AMP and methylxanthines in the frog sciatic nerve
-
Ribeiro JA and Sebastião AM (1984) Enhancement of tetrodotoxin-induced axonal blockade by adenosine, adenosine analogues, dibutyryl cyclic AMP and methylxanthines in the frog sciatic nerve. Br J Pharmacol 83:485–492.
-
(1984)
Br J Pharmacol
, vol.83
, pp. 485-492
-
-
Ribeiro, J.A.1
Sebastião, A.M.2
-
272
-
-
0022591269
-
Adenosine receptors and calcium: Basis for proposing a third (A3) adenosine receptor
-
Ribeiro JA and Sebastião AM (1986) Adenosine receptors and calcium: basis for proposing a third (A3) adenosine receptor. Prog Neurobiol 26:179–209.
-
(1986)
Prog Neurobiol
, vol.26
, pp. 179-209
-
-
Ribeiro, J.A.1
Sebastião, A.M.2
-
273
-
-
84897579298
-
Using caffeine and other adenosine receptor antagonists and agonists as therapeutic tools against neurodegenerative diseases: A review
-
Rivera-Oliver M and Díaz-Ríos M (2014) Using caffeine and other adenosine receptor antagonists and agonists as therapeutic tools against neurodegenerative diseases: a review. Life Sci 101:1–9.
-
(2014)
Life Sci
, vol.101
, pp. 1-9
-
-
Rivera-Oliver, M.1
Díaz-Ríos, M.2
-
274
-
-
0028080865
-
Localization and characterization of adenosine receptor expression in rat testis
-
Rivkees SA (1994) Localization and characterization of adenosine receptor expression in rat testis. Endocrinology 135:2307–2313.
-
(1994)
Endocrinology
, vol.135
, pp. 2307-2313
-
-
Rivkees, S.A.1
-
275
-
-
0034616038
-
Are A3 adenosine receptors expressed in the brain?
-
Rivkees SA, Thevananther S, and Hao H (2000) Are A3 adenosine receptors expressed in the brain? Neuroreport 11:1025–1030.
-
(2000)
Neuroreport
, vol.11
, pp. 1025-1030
-
-
Rivkees, S.A.1
Thevananther, S.2
Hao, H.3
-
276
-
-
70349469872
-
Blockage of A2A and A3 adenosine receptors decreases the desensitization of human GABA(A) receptors microtransplanted to Xenopus oocytes
-
Roseti C, Palma E, Martinello K, Fucile S, Morace R, Esposito V, Cantore G, Arcella A, Giangaspero F, and Aronica E, et al. (2009) Blockage of A2A and A3 adenosine receptors decreases the desensitization of human GABA(A) receptors microtransplanted to Xenopus oocytes. Proc Natl Acad Sci USA 106:15927–15931.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 15927-15931
-
-
Roseti, C.1
Palma, E.2
Martinello, K.3
Fucile, S.4
Morace, R.5
Esposito, V.6
Cantore, G.7
Arcella, A.8
Giangaspero, F.9
Aronica, E.10
-
277
-
-
2942560494
-
Adenosine-activated mast cells induce IgE synthesis by B lymphocytes: An A2B-mediated process involving Th2 cytokines IL-4 and IL-13 with implications for asthma
-
Ryzhov S, Goldstein AE, Matafonov A, Zeng D, Biaggioni I, and Feoktistov I (2004) Adenosine-activated mast cells induce IgE synthesis by B lymphocytes: an A2B-mediated process involving Th2 cytokines IL-4 and IL-13 with implications for asthma. J Immunol 172:7726–7733.
-
(2004)
J Immunol
, vol.172
, pp. 7726-7733
-
-
Ryzhov, S.1
Goldstein, A.E.2
Matafonov, A.3
Zeng, D.4
Biaggioni, I.5
Feoktistov, I.6
-
278
-
-
0029915543
-
Inhibition of TNF-aexpression by adenosine: Role of A3 adenosine receptors
-
Sajjadi FG, Takabayashi K, Foster AC, Domingo RC, and Firestein GS (1996) Inhibition of TNF-a expression by adenosine: role of A3 adenosine receptors. J Immunol 156:3435–3442.
-
(1996)
J Immunol
, vol.156
, pp. 3435-3442
-
-
Sajjadi, F.G.1
Takabayashi, K.2
Foster, A.C.3
Domingo, R.C.4
Firestein, G.S.5
-
279
-
-
0037204734
-
KF26777 (2-(4-bromophenyl)-7,8-dihydro-4-propyl-1H-imidazo[2,1-i]purin-5(4H)-one dihydrochloride), a new potent and selective adenosine A3 receptor antagonist
-
Saki M, Tsumuki H, Nonaka H, Shimada J, and Ichimura M (2002) KF26777 (2-(4-bromophenyl)-7,8-dihydro-4-propyl-1H-imidazo[2,1-i]purin-5(4H)-one dihydrochloride), a new potent and selective adenosine A3 receptor antagonist. Eur J Pharmacol 444: 133–141.
-
(2002)
Eur J Pharmacol
, vol.444
, pp. 133-141
-
-
Saki, M.1
Tsumuki, H.2
Nonaka, H.3
Shimada, J.4
Ichimura, M.5
-
280
-
-
84875663666
-
Differential effect of adenosine receptors on growth of human colon cancer HCT 116 and HT-29 cell lines
-
Sakowicz-Burkiewicz M, Kitowska A, Grden M, Maciejewska I, Szutowicz A, and Pawelczyk T (2013) Differential effect of adenosine receptors on growth of human colon cancer HCT 116 and HT-29 cell lines. Arch Biochem Biophys 533:47–54.
-
(2013)
Arch Biochem Biophys
, vol.533
, pp. 47-54
-
-
Sakowicz-Burkiewicz, M.1
Kitowska, A.2
Grden, M.3
Maciejewska, I.4
Szutowicz, A.5
Pawelczyk, T.6
-
281
-
-
84863642369
-
The mechanism of beta-adrenergic preconditioning: Roles for adenosine and ROS during triggering and mediation
-
Salie R, Moolman JA, and Lochner A (2012) The mechanism of beta-adrenergic preconditioning: roles for adenosine and ROS during triggering and mediation. Basic Res Cardiol 107:281.
-
(2012)
Basic Res Cardiol
, vol.107
-
-
Salie, R.1
Moolman, J.A.2
Lochner, A.3
-
282
-
-
0027500856
-
Molecular cloning and characterization of the human A3 adenosine receptor
-
Salvatore CA, Jacobson MA, Taylor HE, Linden J, and Johnson RG (1993) Molecular cloning and characterization of the human A3 adenosine receptor. Proc Natl Acad Sci USA 90:10365–10369.
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 10365-10369
-
-
Salvatore, C.A.1
Jacobson, M.A.2
Taylor, H.E.3
Linden, J.4
Johnson, R.G.5
-
283
-
-
0034635486
-
Disruption of the A(3) adenosine receptor gene in mice and its effect on stimulated inflammatory cells
-
Salvatore CA, Tilley SL, Latour AM, Fletcher DS, Koller BH, and Jacobson MA (2000) Disruption of the A(3) adenosine receptor gene in mice and its effect on stimulated inflammatory cells. J Biol Chem 275:4429–4434.
-
(2000)
J Biol Chem
, vol.275
, pp. 4429-4434
-
-
Salvatore, C.A.1
Tilley, S.L.2
Latour, A.M.3
Fletcher, D.S.4
Koller, B.H.5
Jacobson, M.A.6
-
284
-
-
84916201971
-
Cardioprotection during chemotherapy: A case study to understand intracellular mechanisms to combat the cardiotoxicity of sunitinib
-
Sandhu H, Cooper S, Eckert M, Pisula L, Chinweike C, Gharanei M, and Maddock HL (2014) Cardioprotection during chemotherapy: a case study to understand intracellular mechanisms to combat the cardiotoxicity of sunitinib. Heart 100:A7–A8.
-
(2014)
Heart
, vol.100
, pp. A7-A8
-
-
Sandhu, H.1
Cooper, S.2
Eckert, M.3
Pisula, L.4
Chinweike, C.5
Gharanei, M.6
Maddock, H.L.7
-
286
-
-
0030610258
-
Adenosine A3 receptor activation produces nociceptive behaviour and edema by release of histamine and 5-hydroxytryptamine
-
Sawynok J, Zarrindast MR, Reid AR, and Doak GJ (1997) Adenosine A3 receptor activation produces nociceptive behaviour and edema by release of histamine and 5-hydroxytryptamine. Eur J Pharmacol 333:1–7.
-
(1997)
Eur J Pharmacol
, vol.333
, pp. 1-7
-
-
Sawynok, J.1
Zarrindast, M.R.2
Reid, A.R.3
Doak, G.J.4
-
287
-
-
22144475862
-
Selective upregulation of the A3 adenosine receptor in eyes with pseudoexfoliation syndrome and glaucoma
-
Schlötzer-Schrehardt U, Zenkel M, Decking U, Haubs D, Kruse FE, Jünemann A, Coca-Prados M, and Naumann GO (2005) Selective upregulation of the A3 adenosine receptor in eyes with pseudoexfoliation syndrome and glaucoma. Invest Ophthalmol Vis Sci 46:2023–2034.
-
(2005)
Invest Ophthalmol Vis Sci
, vol.46
, pp. 2023-2034
-
-
Schlötzer-Schrehardt, U.1
Zenkel, M.2
Decking, U.3
Haubs, D.4
Kruse, F.E.5
Jünemann, A.6
Coca-Prados, M.7
Naumann, G.O.8
-
288
-
-
0033851227
-
Human adenosine A(1), A(2A), A(2B), and A(3) receptors expressed in Chinese hamster ovary cells all mediate the phosphorylation of extracellular-regulated kinase 1/2
-
Schulte G and Fredholm BB (2000) Human adenosine A(1), A(2A), A(2B), and A(3) receptors expressed in Chinese hamster ovary cells all mediate the phosphorylation of extracellular-regulated kinase 1/2. Mol Pharmacol 58:477–482.
-
(2000)
Mol Pharmacol
, vol.58
, pp. 477-482
-
-
Schulte, G.1
Fredholm, B.B.2
-
289
-
-
0036841034
-
Signaling pathway from the human adenosine A (3) receptor expressed in Chinese hamster ovary cells to the extracellular signalregulated kinase 1/2
-
Schulte G and Fredholm BB (2002) Signaling pathway from the human adenosine A (3) receptor expressed in Chinese hamster ovary cells to the extracellular signalregulated kinase 1/2. Mol Pharmacol 62:1137–1146.
-
(2002)
Mol Pharmacol
, vol.62
, pp. 1137-1146
-
-
Schulte, G.1
Fredholm, B.B.2
-
290
-
-
84869024880
-
From A1 to A3 en passant through A (2A) receptors in the hippocampus: Pharmacological implications
-
Sebastiao AM, Ribeiro FF, and Ribeiro JA (2012) From A1 to A3 en passant through A (2A) receptors in the hippocampus: pharmacological implications. CNS Neurol Disord Drug Targets 11:652–663.
-
(2012)
CNS Neurol Disord Drug Targets
, vol.11
, pp. 652-663
-
-
Sebastiao, A.M.1
Ribeiro, F.F.2
Ribeiro, J.A.3
-
291
-
-
0030819798
-
Adenosine A3 receptor agonist-induced neurotoxicity in rat cerebellar granule neurons
-
Sei Y, Von Lubitz DKJE, Abbracchio MP, Ji X-D, and Jacobson KA (1997) Adenosine A3 receptor agonist-induced neurotoxicity in rat cerebellar granule neurons. Drug Dev Res 40:267–273.
-
(1997)
Drug Dev Res
, vol.40
, pp. 267-273
-
-
Sei, Y.1
Von Lubitz, D.2
Abbracchio, M.P.3
Ji, X.-D.4
Jacobson, K.A.5
-
292
-
-
0029876530
-
Adenosine-induced vasoconstriction in vivo. Role of the mast cell and A3 adenosine receptor
-
Shepherd RK, Linden J, and Duling BR (1996) Adenosine-induced vasoconstriction in vivo. Role of the mast cell and A3 adenosine receptor. Circ Res 78:627–634.
-
(1996)
Circ Res
, vol.78
, pp. 627-634
-
-
Shepherd, R.K.1
Linden, J.2
Duling, B.R.3
-
293
-
-
21244457219
-
Role of adenosine A1 and A3 receptors in regulation of cardiomyocyte homeostasis after mitochondrial respiratory chain injury
-
Shneyvays V, Leshem D, Zinman T, Mamedova LK, Jacobson KA, and Shainberg A (2005) Role of adenosine A1 and A3 receptors in regulation of cardiomyocyte homeostasis after mitochondrial respiratory chain injury. Am J Physiol Heart Circ Physiol 288:H2792–H2801.
-
(2005)
Am J Physiol Heart Circ Physiol
, vol.288
, pp. H2792-H2801
-
-
Shneyvays, V.1
Leshem, D.2
Zinman, T.3
Mamedova, L.K.4
Jacobson, K.A.5
Shainberg, A.6
-
294
-
-
0034948867
-
Activation of A(3)adenosine receptor protects against doxorubicin-induced cardiotoxicity
-
Shneyvays V, Mamedova L, Zinman T, Jacobson K, and Shainberg A (2001) Activation of A(3)adenosine receptor protects against doxorubicin-induced cardiotoxicity. J Mol Cell Cardiol 33:1249–1261.
-
(2001)
J Mol Cell Cardiol
, vol.33
, pp. 1249-1261
-
-
Shneyvays, V.1
Mamedova, L.2
Zinman, T.3
Jacobson, K.4
Shainberg, A.5
-
295
-
-
0032531207
-
Induction of apoptosis in cardiac myocytes by an A3 adenosine receptor agonist
-
Shneyvays V, Nawrath H, Jacobson KA, and Shainberg A (1998) Induction of apoptosis in cardiac myocytes by an A3 adenosine receptor agonist. Exp Cell Res 243: 383–397.
-
(1998)
Exp Cell Res
, vol.243
, pp. 383-397
-
-
Shneyvays, V.1
Nawrath, H.2
Jacobson, K.A.3
Shainberg, A.4
-
296
-
-
9244246875
-
Analysis of calcium responses mediated by the A3 adenosine receptor in cultured newborn rat cardiac myocytes
-
Shneyvays V, Zinman T, and Shainberg A (2004) Analysis of calcium responses mediated by the A3 adenosine receptor in cultured newborn rat cardiac myocytes. Cell Calcium 36:387–396.
-
(2004)
Cell Calcium
, vol.36
, pp. 387-396
-
-
Shneyvays, V.1
Zinman, T.2
Shainberg, A.3
-
297
-
-
0028915714
-
Search for new purine- and ribose-modified adenosine analogues as selective agonists and antagonists at adenosine receptors
-
Siddiqi SM, Jacobson KA, Esker JL, Olah ME, Ji XD, Melman N, Tiwari KN, Secrist JA 3rd, Schneller SW, and Cristalli G, et al. (1995) Search for new purine- and ribose-modified adenosine analogues as selective agonists and antagonists at adenosine receptors. J Med Chem 38:1174–1188.
-
(1995)
J Med Chem
, vol.38
, pp. 1174-1188
-
-
Siddiqi, S.M.1
Jacobson, K.A.2
Esker, J.L.3
Olah, M.E.4
Ji, X.D.5
Melman, N.6
Tiwari, K.N.7
Secrist, J.A.8
Schneller, S.W.9
Cristalli, G.10
-
298
-
-
38149051473
-
Clinical evidence for utilization of the A3 adenosine receptor as a target to treat rheumatoid arthritis: Data from a phase II clinical trial
-
Silverman MH, Strand V, Markovits D, Nahir M, Reitblat T, Molad Y, Rosner I, Rozenbaum M, Mader R, and Adawi M, et al. (2008) Clinical evidence for utilization of the A3 adenosine receptor as a target to treat rheumatoid arthritis: data from a phase II clinical trial. J Rheumatol 35:41–48.
-
(2008)
J Rheumatol
, vol.35
, pp. 41-48
-
-
Silverman, M.H.1
Strand, V.2
Markovits, D.3
Nahir, M.4
Reitblat, T.5
Molad, Y.6
Rosner, I.7
Rozenbaum, M.8
Mader, R.9
Adawi, M.10
-
299
-
-
0037073605
-
A role for histamine in cytokine modulation by the adenosine A(3) receptor agonist, 2-Cl-IB-MECA
-
Smith SR, Denhardt G, and Terminelli C (2002) A role for histamine in cytokine modulation by the adenosine A(3) receptor agonist, 2-Cl-IB-MECA. Eur J Pharmacol 457:57–69.
-
(2002)
Eur J Pharmacol
, vol.457
, pp. 57-69
-
-
Smith, S.R.1
Denhardt, G.2
Terminelli, C.3
-
300
-
-
84901319344
-
Combination of Cl‑IB‑MECA with paclitaxel is a highly effective cytotoxic therapy causing mTOR‑dependent autophagy and mitotic catastrophe on human melanoma cells
-
Soares AS, Costa VM, Diniz C, and Fresco P (2014) Combination of Cl‑IB‑MECA with paclitaxel is a highly effective cytotoxic therapy causing mTOR‑dependent autophagy and mitotic catastrophe on human melanoma cells. J Cancer Res Clin Oncol 140:921–935.
-
(2014)
J Cancer Res Clin Oncol
, vol.140
, pp. 921-935
-
-
Soares, A.S.1
Costa, V.M.2
Diniz, C.3
Fresco, P.4
-
301
-
-
33644778637
-
Adenosine in the airways: Implications and applications
-
Spicuzza L, Di Maria G, and Polosa R (2006) Adenosine in the airways: implications and applications. Eur J Pharmacol 533:77–88.
-
(2006)
Eur J Pharmacol
, vol.533
, pp. 77-88
-
-
Spicuzza, L.1
Di Maria, G.2
Polosa, R.3
-
302
-
-
84861931513
-
Adenosine receptor expression in rheumatoid synovium: A basis for methotrexate action
-
Stamp LK, Hazlett J, Roberts RL, Frampton C, Highton J, and Hessian PA (2012) Adenosine receptor expression in rheumatoid synovium: a basis for methotrexate action. Arthritis Res Ther 14:R138.
-
(2012)
Arthritis Res Ther
, vol.14
-
-
Stamp, L.K.1
Hazlett, J.2
Roberts, R.L.3
Frampton, C.4
Highton, J.5
Hessian, P.A.6
-
303
-
-
84873044693
-
CF102 for the treatment of hepatocellular carcinoma: A phase I/II, open-label, dose-escalation study
-
Stemmer SM, Benjaminov O, Medalia G, Ciuraru NB, Silverman MH, Bar-Yehuda S, Fishman S, Harpaz Z, Farbstein M, and Cohen S, et al. (2013) CF102 for the treatment of hepatocellular carcinoma: a phase I/II, open-label, dose-escalation study. Oncologist 18:25–26.
-
(2013)
Oncologist
, vol.18
, pp. 25-26
-
-
Stemmer, S.M.1
Benjaminov, O.2
Medalia, G.3
Ciuraru, N.B.4
Silverman, M.H.5
Bar-Yehuda, S.6
Fishman, S.7
Harpaz, Z.8
Farbstein, M.9
Cohen, S.10
-
304
-
-
84905028134
-
Effect of a toggle switch mutation in TM6 of the human adenosine A₃receptor on Gi protein-dependent signalling and Gi-independent receptor internalization
-
Stoddart LA, Kellam B, Briddon SJ, and Hill SJ (2014) Effect of a toggle switch mutation in TM6 of the human adenosine A₃ receptor on Gi protein-dependent signalling and Gi-independent receptor internalization. Br J Pharmacol 171: 3827–3844.
-
(2014)
Br J Pharmacol
, vol.171
, pp. 3827-3844
-
-
Stoddart, L.A.1
Kellam, B.2
Briddon, S.J.3
Hill, S.J.4
-
305
-
-
0034840213
-
Pharmacological characterization of adenosine receptors in PGT-beta mouse pineal gland tumour cells
-
Suh BC, Kim TD, Lee JU, Seong JK, and Kim KT (2001) Pharmacological characterization of adenosine receptors in PGT-beta mouse pineal gland tumour cells. Br J Pharmacol 134:132–142.
-
(2001)
Br J Pharmacol
, vol.134
, pp. 132-142
-
-
Suh, B.C.1
Kim, T.D.2
Lee, J.U.3
Seong, J.K.4
Kim, K.T.5
-
306
-
-
0031691973
-
Suppression of macrophage inflammatory protein (MIP)-1alpha production and collagen-induced arthritis by adenosine receptor agonists
-
Szabó C, Scott GS, Virág L, Egnaczyk G, Salzman AL, Shanley TP, and Haskó G (1998) Suppression of macrophage inflammatory protein (MIP)-1alpha production and collagen-induced arthritis by adenosine receptor agonists. Br J Pharmacol 125:379–387.
-
(1998)
Br J Pharmacol
, vol.125
, pp. 379-387
-
-
Szabó, C.1
Scott, G.S.2
Virág, L.3
Egnaczyk, G.4
Salzman, A.L.5
Shanley, T.P.6
Haskó, G.7
-
307
-
-
77952711968
-
Novel N2-substituted pyrazolo [3,4-d]pyrimidine adenosine A3 receptor antagonists: Inhibition of A3-mediated human glioblastoma cell proliferation
-
Taliani S, La Motta C, Mugnaini L, Simorini F, Salerno S, Marini AM, Da Settimo F, Cosconati S, Cosimelli B, and Greco G, et al. (2010) Novel N2-substituted pyrazolo [3,4-d]pyrimidine adenosine A3 receptor antagonists: inhibition of A3-mediated human glioblastoma cell proliferation. J Med Chem 53:3954–3963.
-
(2010)
J Med Chem
, vol.53
, pp. 3954-3963
-
-
Taliani, S.1
La Motta, C.2
Mugnaini, L.3
Simorini, F.4
Salerno, S.5
Marini, A.M.6
Da Settimo, F.7
Cosconati, S.8
Cosimelli, B.9
Greco, G.10
-
308
-
-
0036083280
-
Targeted deletion of adenosine A(3) receptors augments adenosine-induced coronary flow in isolated mouse heart
-
Talukder MA, Morrison RR, Jacobson MA, Jacobson KA, Ledent C, and Mustafa SJ (2002) Targeted deletion of adenosine A(3) receptors augments adenosine-induced coronary flow in isolated mouse heart. Am J Physiol Heart Circ Physiol 282: H2183–H2189.
-
(2002)
Am J Physiol Heart Circ Physiol
, vol.282
, pp. H2183-H2189
-
-
Talukder, M.A.1
Morrison, R.R.2
Jacobson, M.A.3
Jacobson, K.A.4
Ledent, C.5
Mustafa, S.J.6
-
309
-
-
15444378502
-
Gao ZG, and Jacobson KA (2005) (N)-methanocarba 2,N6-disubstituted adenine nucleosides as highly potent and selective A3 adenosine receptor agonists
-
Tchilibon S, Joshi BV, Kim SK, Duong HT, Gao ZG, and Jacobson KA (2005) (N)-methanocarba 2,N6-disubstituted adenine nucleosides as highly potent and selective A3 adenosine receptor agonists. J Med Chem 48:1745–1758.
-
J Med Chem
, vol.48
, pp. 1745-1758
-
-
Tchilibon, S.1
Joshi, B.V.2
Kim, S.K.3
Duong, H.T.4
-
310
-
-
84872358351
-
Functional and RNA expression profile of adenosine receptor subtypes in mouse mesenteric arteries
-
Teng B, Fil D, Tilley SL, Ledent C, Krahn T, and Mustafa SJ (2013) Functional and RNA expression profile of adenosine receptor subtypes in mouse mesenteric arteries. J Cardiovasc Pharmacol 61:70–76.
-
(2013)
J Cardiovasc Pharmacol
, vol.61
, pp. 70-76
-
-
Teng, B.1
Fil, D.2
Tilley, S.L.3
Ledent, C.4
Krahn, T.5
Mustafa, S.J.6
-
311
-
-
1342281409
-
Regulation of adenosine receptor subtypes during cultivation of human monocytes: Role of receptors in preventing lipopolysaccharide-triggered respiratory burst
-
Thiele A, Kronstein R, Wetzel A, Gerth A, Nieber K, and Hauschildt S (2004) Regulation of adenosine receptor subtypes during cultivation of human monocytes: role of receptors in preventing lipopolysaccharide-triggered respiratory burst. Infect Immun 72:1349–1357.
-
(2004)
Infect Immun
, vol.72
, pp. 1349-1357
-
-
Thiele, A.1
Kronstein, R.2
Wetzel, A.3
Gerth, A.4
Nieber, K.5
Hauschildt, S.6
-
312
-
-
0032867231
-
Adenosine A(3)-receptor stimulation attenuates postischemic dysfunction through K(ATP) channels
-
Thourani VH, Nakamura M, Ronson RS, Jordan JE, Zhao Z-Q, Levy JH, Szlam F, Guyton RA, and Vinten-Johansen J (1999a) Adenosine A(3)-receptor stimulation attenuates postischemic dysfunction through K(ATP) channels. Am J Physiol 277: H228–H235.
-
(1999)
Am J Physiol
, vol.277
, pp. H228-H235
-
-
Thourani, V.H.1
Nakamura, M.2
Ronson, R.S.3
Jordan, J.E.4
Zhao, Z.-Q.5
Levy, J.H.6
Szlam, F.7
Guyton, R.A.8
Vinten-Johansen, J.9
-
313
-
-
0032587022
-
Adenosine A3 pretreatment before cardioplegic arrest attenuates postischemic cardiac dysfunction
-
Thourani VH, Ronson RS, Jordan JE, Guyton RA, and Vinten-Johansen J (1999b) Adenosine A3 pretreatment before cardioplegic arrest attenuates postischemic cardiac dysfunction. Ann Thorac Surg 67:1732–1737.
-
(1999)
Ann Thorac Surg
, vol.67
, pp. 1732-1737
-
-
Thourani, V.H.1
Ronson, R.S.2
Jordan, J.E.3
Guyton, R.A.4
Vinten-Johansen, J.5
-
314
-
-
0038375944
-
Identification of A3 receptor- and mast cell-dependent and -independent components of adenosine-mediated airway responsiveness in mice
-
Tilley SL, Tsai M, Williams CM, Wang ZS, Erikson CJ, Galli SJ, and Koller BH (2003) Identification of A3 receptor- and mast cell-dependent and -independent components of adenosine-mediated airway responsiveness in mice. J Immunol 171: 331–337.
-
(2003)
J Immunol
, vol.171
, pp. 331-337
-
-
Tilley, S.L.1
Tsai, M.2
Williams, C.M.3
Wang, Z.S.4
Erikson, C.J.5
Galli, S.J.6
Koller, B.H.7
-
315
-
-
0033965558
-
Adenosine and inosine increase cutaneous vasopermeability by activating A(3) receptors on mast cells
-
Tilley SL, Wagoner VA, Salvatore CA, Jacobson MA, and Koller BH (2000) Adenosine and inosine increase cutaneous vasopermeability by activating A(3) receptors on mast cells. J Clin Invest 105:361–367.
-
(2000)
J Clin Invest
, vol.105
, pp. 361-367
-
-
Tilley, S.L.1
Wagoner, V.A.2
Salvatore, C.A.3
Jacobson, M.A.4
Koller, B.H.5
-
316
-
-
77049109479
-
Polyamidoamine (PAMAM) dendrimer conjugates of “clickable” agonists of the A3 adenosine receptor and coactivation of the P2Y14 receptor by a tethered nucleotide
-
Tosh DK, Yoo LS, Chinn M, Hong K, Kilbey SM 2nd, Barrett MO, Fricks IP, Harden TK, Gao ZG, and Jacobson KA (2010) Polyamidoamine (PAMAM) dendrimer conjugates of “clickable” agonists of the A3 adenosine receptor and coactivation of the P2Y14 receptor by a tethered nucleotide. Bioconjug Chem 21:372–384.
-
(2010)
Bioconjug Chem
, vol.21
, pp. 372-384
-
-
Tosh, D.K.1
Yoo, L.S.2
Chinn, M.3
Hong, K.4
Kilbey, S.M.5
Barrett, M.O.6
Fricks, I.P.7
Harden, T.K.8
Gao, Z.G.9
Jacobson, K.A.10
-
317
-
-
0030615054
-
Selective adenosine A3 receptor stimulation reduces ischemic myocardial injury in the rabbit heart
-
Tracey WR, Magee W, Masamune H, Kennedy SP, Knight DR, Buchholz RA, and Hill RJ (1997) Selective adenosine A3 receptor stimulation reduces ischemic myocardial injury in the rabbit heart. Cardiovasc Res 33:410–415.
-
(1997)
Cardiovasc Res
, vol.33
, pp. 410-415
-
-
Tracey, W.R.1
Magee, W.2
Masamune, H.3
Kennedy, S.P.4
Knight, D.R.5
Buchholz, R.A.6
Hill, R.J.7
-
318
-
-
0032190313
-
Selective activation of adenosine A3 receptors with N6-(3-chlorobenzyl)-59-N-methylcarboxamidoadenosine (CB-MECA) provides cardioprotection via KATP channel activation
-
Tracey WR, Magee W, Masamune H, Oleynek JJ, and Hill RJ (1998) Selective activation of adenosine A3 receptors with N6-(3-chlorobenzyl)-59-N-methylcarboxamidoadenosine (CB-MECA) provides cardioprotection via KATP channel activation. Cardiovasc Res 40: 138–145.
-
(1998)
Cardiovasc Res
, vol.40
, pp. 138-145
-
-
Tracey, W.R.1
Magee, W.2
Masamune, H.3
Oleynek, J.J.4
Hill, R.J.5
-
319
-
-
0036882256
-
A3 adenosine receptors in human astrocytoma cells: Agonist-mediated desensitization, internalization, and down-regulation
-
Trincavelli ML, Tuscano D, Marroni M, Falleni A, Gremigni V, Ceruti S, Abbracchio MP, Jacobson KA, Cattabeni F, and Martini C (2002a) A3 adenosine receptors in human astrocytoma cells: agonist-mediated desensitization, internalization, and down-regulation. Mol Pharmacol 62:1373–1384.
-
(2002)
Mol Pharmacol
, vol.62
, pp. 1373-1384
-
-
Trincavelli, M.L.1
Tuscano, D.2
Marroni, M.3
Falleni, A.4
Gremigni, V.5
Ceruti, S.6
Abbracchio, M.P.7
Jacobson, K.A.8
Cattabeni, F.9
Martini, C.10
-
320
-
-
0037135692
-
Involvement of mitogen protein kinase cascade in agonist-mediated human A(3) adenosine receptor regulation
-
Trincavelli ML, Tuscano D, Marroni M, Klotz KN, Lucacchini A, and Martini C (2002b) Involvement of mitogen protein kinase cascade in agonist-mediated human A(3) adenosine receptor regulation. Biochim Biophys Acta 1591:55–62.
-
(2002)
Biochim Biophys Acta
, vol.1591
, pp. 55-62
-
-
Trincavelli, M.L.1
Tuscano, D.2
Marroni, M.3
Klotz, K.N.4
Lucacchini, A.5
Martini, C.6
-
321
-
-
0037357314
-
The effect of perfusion with UW solution on the skeletal muscle and vascular endothelial exocrine function in rat hindlimbs
-
Tsuchida T, Kato T, Yamaga M, Ikebe K, Oniki Y, Irie H, and Takagi K (2003) The effect of perfusion with UW solution on the skeletal muscle and vascular endothelial exocrine function in rat hindlimbs. J Surg Res 110:266–271.
-
(2003)
J Surg Res
, vol.110
, pp. 266-271
-
-
Tsuchida, T.1
Kato, T.2
Yamaga, M.3
Ikebe, K.4
Oniki, Y.5
Irie, H.6
Takagi, K.7
-
322
-
-
84859621907
-
(2012) Adenosine A3 receptor stimulation reduces muscle injury following physical trauma and is associated with alterations in the MMP/TIMP response
-
Urso ML, Wang R, Zambraski EJ, and Liang BT (2012) Adenosine A3 receptor stimulation reduces muscle injury following physical trauma and is associated with alterations in the MMP/TIMP response. J Appl Physiol (1985) 112:658–670.
-
(1985)
J Appl Physiol
, vol.112
, pp. 658-670
-
-
Urso, M.L.1
Wang, R.2
Zambraski, E.J.3
Liang, B.T.4
-
323
-
-
50449094182
-
Activation of the A(3) adenosine receptor suppresses superoxide production and chemotaxis of mouse bone marrow neutrophils
-
van der Hoeven D, Wan TC, and Auchampach JA (2008) Activation of the A(3) adenosine receptor suppresses superoxide production and chemotaxis of mouse bone marrow neutrophils. Mol Pharmacol 74:685–696.
-
(2008)
Mol Pharmacol
, vol.74
, pp. 685-696
-
-
Van Der Hoeven, D.1
Wan, T.C.2
Auchampach, J.A.3
-
324
-
-
67649209807
-
Differential expression of adenosine A3 receptors controls adenosine A2A receptor-mediated inhibition of TLR responses in microglia
-
van der Putten C, Zuiderwijk-Sick EA, van Straalen L, de Geus ED, Boven LA, Kondova I, IJzerman AP, and Bajramovic JJ (2009) Differential expression of adenosine A3 receptors controls adenosine A2A receptor-mediated inhibition of TLR responses in microglia. J Immunol 182:7603–7612.
-
(2009)
J Immunol
, vol.182
, pp. 7603-7612
-
-
Van Der Putten, C.1
Zuiderwijk-Sick, E.A.2
Van Straalen, L.3
De Geus, E.D.4
Boven, L.A.5
Kondova, I.6
Ijzerman, A.P.7
Bajramovic, J.J.8
-
325
-
-
0034213365
-
-
van Muijlwijk-Koezen JE, Timmerman H, van der Goot H, Menge WM, Frijtag Von Drabbe Künzel J, de Groote M, IJzerman AP, and IJzerman AP (2000) Isoquinoline and quinazoline urea analogues as antagonists for the human adenosine A(3) receptor. J Med Chem 43:2227–2238.
-
(2000)
Isoquinoline and Quinazoline Urea Analogues as Antagonists for the Human Adenosine A(3) Receptor. J Med Chem
, vol.43
, pp. 2227-2238
-
-
Van Muijlwijk-Koezen, J.E.1
Timmerman, H.2
Van Der Goot, H.3
Menge, W.M.4
Frijtag Von Drabbe Künzel, J.5
De Groote, M.6
Ijzerman, A.P.7
Ijzerman, A.P.8
-
326
-
-
6344278503
-
Tolerability, pharmacokinetics and concentration-dependent hemodynamic effects of oral CF101, an A3 adenosine receptor agonist, in healthy young men
-
van Troostenburg AR, Clark EV, Carey WD, Warrington SJ, Kerns WD, Cohn I, Silverman MH, Bar-Yehuda S, Fong KL, and Fishman P (2004) Tolerability, pharmacokinetics and concentration-dependent hemodynamic effects of oral CF101, an A3 adenosine receptor agonist, in healthy young men. Int J Clin Pharmacol Ther 42:534–542.
-
(2004)
Int J Clin Pharmacol Ther
, vol.42
, pp. 534-542
-
-
Van Troostenburg, A.R.1
Clark, E.V.2
Carey, W.D.3
Warrington, S.J.4
Kerns, W.D.5
Cohn, I.6
Silverman, M.H.7
Bar-Yehuda, S.8
Fong, K.L.9
Fishman, P.10
-
327
-
-
32444448624
-
Alteration of adenosine receptors in patients with chronic obstructive pulmonary disease
-
Varani K, Caramori G, Vincenzi F, Adcock I, Casolari P, Leung E, Maclennan S, Gessi S, Morello S, and Barnes PJ, et al. (2006) Alteration of adenosine receptors in patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med 173:398–406.
-
(2006)
Am J Respir Crit Care Med
, vol.173
, pp. 398-406
-
-
Varani, K.1
Caramori, G.2
Vincenzi, F.3
Adcock, I.4
Casolari, P.5
Leung, E.6
Maclennan, S.7
Gessi, S.8
Morello, S.9
Barnes, P.J.10
-
328
-
-
77951642313
-
Oxidative/nitrosative stress selectively altered A(2B) adenosine receptors in chronic obstructive pulmonary disease
-
Varani K, Caramori G, Vincenzi F, Tosi A, Barczyk A, Contoli M, Casolari P, Triggiani M, Hansel T, and Leung E, et al. (2010) Oxidative/nitrosative stress selectively altered A(2B) adenosine receptors in chronic obstructive pulmonary disease. FASEB J 24:1192–1204.
-
(2010)
FASEB J
, vol.24
, pp. 1192-1204
-
-
Varani, K.1
Caramori, G.2
Vincenzi, F.3
Tosi, A.4
Barczyk, A.5
Contoli, M.6
Casolari, P.7
Triggiani, M.8
Hansel, T.9
Leung, E.10
-
329
-
-
39749113815
-
Characterization of adenosine receptors in bovine chondrocytes and fibroblast-like synoviocytes exposed to low frequency low energy pulsed electromagnetic fields
-
Varani K, De Mattei M, Vincenzi F, Gessi S, Merighi S, Pellati A, Ongaro A, Caruso A, Cadossi R, and Borea PA (2008) Characterization of adenosine receptors in bovine chondrocytes and fibroblast-like synoviocytes exposed to low frequency low energy pulsed electromagnetic fields. Osteoarthritis Cartilage 16:292–304.
-
(2008)
Osteoarthritis Cartilage
, vol.16
, pp. 292-304
-
-
Varani, K.1
De Mattei, M.2
Vincenzi, F.3
Gessi, S.4
Merighi, S.5
Pellati, A.6
Ongaro, A.7
Caruso, A.8
Cadossi, R.9
Borea, P.A.10
-
330
-
-
79951842443
-
Areceptors are overexpressed in pleura from patients with mesothelioma and reduce cell growth via Akt/nuclear factor-kB pathway
-
Varani K, Maniero S, Vincenzi F, Targa M, Stefanelli A, Maniscalco P, Martini F, Tognon M, and Borea PA (2011a) A receptors are overexpressed in pleura from patients with mesothelioma and reduce cell growth via Akt/nuclear factor-kB pathway. Am J Respir Crit Care Med 183:522–530.
-
(2011)
Am J Respir Crit Care Med
, vol.183
, pp. 522-530
-
-
Varani, K.1
Maniero, S.2
Vincenzi, F.3
Targa, M.4
Stefanelli, A.5
Maniscalco, P.6
Martini, F.7
Tognon, M.8
Borea, P.A.9
-
331
-
-
70349773147
-
Normalization of A2A and A3 adenosine receptor up-regulation in rheumatoid arthritis patients by treatment with anti-tumor necrosis factor alpha but not methotrexate
-
Varani K, Massara A, Vincenzi F, Tosi A, Padovan M, Trotta F, and Borea PA (2009) Normalization of A2A and A3 adenosine receptor up-regulation in rheumatoid arthritis patients by treatment with anti-tumor necrosis factor alpha but not methotrexate. Arthritis Rheum 60:2880–2891.
-
(2009)
Arthritis Rheum
, vol.60
, pp. 2880-2891
-
-
Varani, K.1
Massara, A.2
Vincenzi, F.3
Tosi, A.4
Padovan, M.5
Trotta, F.6
Borea, P.A.7
-
332
-
-
17544384891
-
Spalluto G, and Borea PA (2000) [(3)H]MRE 3008F20: A novel antagonist radioligand for the pharmacological and biochemical characterization of human A(3) adenosine receptors
-
Varani K, Merighi S, Gessi S, Klotz KN, Leung E, Baraldi PG, Cacciari B, Romagnoli R, Spalluto G, and Borea PA (2000) [(3)H]MRE 3008F20: a novel antagonist radioligand for the pharmacological and biochemical characterization of human A(3) adenosine receptors. Mol Pharmacol 57:968–975.
-
Mol Pharmacol
, vol.57
, pp. 968-975
-
-
Varani, K.1
Merighi, S.2
Gessi, S.3
Klotz, K.N.4
Leung, E.5
Baraldi, P.G.6
Cacciari, B.7
Romagnoli, R.8
-
333
-
-
78650417131
-
The role of adenosine receptors in rheumatoid arthritis
-
Varani K, Padovan M, Govoni M, Vincenzi F, Trotta F, and Borea PA (2010a) The role of adenosine receptors in rheumatoid arthritis. Autoimmun Rev 10:61–64.
-
(2010)
Autoimmun Rev
, vol.10
, pp. 61-64
-
-
Varani, K.1
Padovan, M.2
Govoni, M.3
Vincenzi, F.4
Trotta, F.5
Borea, P.A.6
-
334
-
-
82655177570
-
A2A and A3 adenosine receptor expression in rheumatoid arthritis: Upregulation, inverse correlation with disease activity score and suppression of inflammatory cytokine and metalloproteinase release
-
Varani K, Padovan M, Vincenzi F, Targa M, Trotta F, Govoni M, and Borea PA (2011b) A2A and A3 adenosine receptor expression in rheumatoid arthritis: upregulation, inverse correlation with disease activity score and suppression of inflammatory cytokine and metalloproteinase release. Arthritis Res Ther 13:R197.
-
(2011)
Arthritis Res Ther
, vol.13
-
-
Varani, K.1
Padovan, M.2
Vincenzi, F.3
Targa, M.4
Trotta, F.5
Govoni, M.6
Borea, P.A.7
-
335
-
-
76149098862
-
A2A adenosine receptor overexpression and functionality, as well as TNF-alpha levels, correlate with motor symptoms in Parkinson’s disease
-
Varani K, Vincenzi F, Tosi A, Gessi S, Casetta I, Granieri G, Fazio P, Leung E, MacLennan S, and Granieri E, et al. (2010b) A2A adenosine receptor overexpression and functionality, as well as TNF-alpha levels, correlate with motor symptoms in Parkinson’s disease. FASEB J 24:587–598.
-
(2010)
FASEB J
, vol.24
, pp. 587-598
-
-
Varani, K.1
Vincenzi, F.2
Tosi, A.3
Gessi, S.4
Casetta, I.5
Granieri, G.6
Fazio, P.7
Leung, E.8
Maclennan, S.9
Granieri, E.10
-
336
-
-
77950933196
-
Expression and functional role of adenosine receptors in regulating inflammatory responses in human synoviocytes
-
Varani K, Vincenzi F, Tosi A, Targa M, Masieri FF, Ongaro A, De Mattei M, Massari L, and Borea PA (2010c) Expression and functional role of adenosine receptors in regulating inflammatory responses in human synoviocytes. Br J Pharmacol 160: 101–115.
-
(2010)
Br J Pharmacol
, vol.160
, pp. 101-115
-
-
Varani, K.1
Vincenzi, F.2
Tosi, A.3
Targa, M.4
Masieri, F.F.5
Ongaro, A.6
De Mattei, M.7
Massari, L.8
Borea, P.A.9
-
337
-
-
84872102720
-
The stimulation of A(3) adenosine receptors reduces bone-residing breast cancer in a rat preclinical model
-
Varani K, Vincenzi F, Targa M, Paradiso B, Parrilli A, Fini M, Lanza G, and Borea PA (2013) The stimulation of A(3) adenosine receptors reduces bone-residing breast cancer in a rat preclinical model. Eur J Cancer 49:482–491.
-
(2013)
Eur J Cancer
, vol.49
, pp. 482-491
-
-
Varani, K.1
Vincenzi, F.2
Targa, M.3
Paradiso, B.4
Parrilli, A.5
Fini, M.6
Lanza, G.7
Borea, P.A.8
-
338
-
-
54149115153
-
Activation of the adenosine-A3 receptor stimulates matrix metalloproteinase-9 secretion by macrophages
-
Velot E, Haas B, Léonard F, Ernens I, Rolland-Turner M, Schwartz C, Longrois D, Devaux Y, and Wagner DR (2008) Activation of the adenosine-A3 receptor stimulates matrix metalloproteinase-9 secretion by macrophages. Cardiovasc Res 80: 246–254.
-
(2008)
Cardiovasc Res
, vol.80
, pp. 246-254
-
-
Velot, E.1
Haas, B.2
Léonard, F.3
Ernens, I.4
Rolland-Turner, M.5
Schwartz, C.6
Longrois, D.7
Devaux, Y.8
Wagner, D.R.9
-
339
-
-
84878622750
-
Pulsed electromagnetic fields increased the antiinflammatory effect of AA and Aadenosine receptors in human T/C-28a2 chondrocytes and hFOB 1.19 osteoblasts
-
Vincenzi F, Targa M, Corciulo C, Gessi S, Merighi S, Setti S, Cadossi R, Goldring MB, Borea PA, and Varani K (2013) Pulsed electromagnetic fields increased the antiinflammatory effect of AA and A adenosine receptors in human T/C-28a2 chondrocytes and hFOB 1.19 osteoblasts. PLoS ONE 8:e65561.
-
(2013)
Plos ONE
, vol.8
-
-
Vincenzi, F.1
Targa, M.2
Corciulo, C.3
Gessi, S.4
Merighi, S.5
Setti, S.6
Cadossi, R.7
Goldring, M.B.8
Borea, P.A.9
Varani, K.10
-
340
-
-
84862695783
-
The anti-tumor effect of A3 adenosine receptors is potentiated by pulsed electromagnetic fields in cultured neural cancer cells
-
Vincenzi F, Targa M, Corciulo C, Gessi S, Merighi S, Setti S, Cadossi R, Borea PA, and Varani K (2012) The anti-tumor effect of A3 adenosine receptors is potentiated by pulsed electromagnetic fields in cultured neural cancer cells. PLoS ONE 7: e39317.
-
(2012)
Plos ONE
, vol.7
-
-
Vincenzi, F.1
Targa, M.2
Corciulo, C.3
Gessi, S.4
Merighi, S.5
Setti, S.6
Cadossi, R.7
Borea, P.A.8
Varani, K.9
-
341
-
-
0037130186
-
N(6)-alkyl-2-alkynyl derivatives of adenosine as potent and selective agonists at the human adenosine A(3) receptor and a starting point for searching A(2B) ligands
-
Volpini R, Costanzi S, Lambertucci C, Taffi S, Vittori S, Klotz KN, and Cristalli G (2002) N(6)-alkyl-2-alkynyl derivatives of adenosine as potent and selective agonists at the human adenosine A(3) receptor and a starting point for searching A(2B) ligands. J Med Chem 45:3271–3279.
-
(2002)
J Med Chem
, vol.45
, pp. 3271-3279
-
-
Volpini, R.1
Costanzi, S.2
Lambertucci, C.3
Taffi, S.4
Vittori, S.5
Klotz, K.N.6
Cristalli, G.7
-
342
-
-
72249085783
-
Synthesis and biological evaluation of 2-alkynyl-N6-methyl-59-N-methylcarboxamidoadenosine derivatives as potent and highly selective agonists for the human adenosine A3 receptor
-
Volpini R, Buccioni M, Dal Ben D, Lambertucci C, Lammi C, Marucci G, Ramadori AT, Klotz KN, and Cristalli G (2009) Synthesis and biological evaluation of 2-alkynyl-N6-methyl-59-N-methylcarboxamidoadenosine derivatives as potent and highly selective agonists for the human adenosine A3 receptor. J Med Chem 52: 7897–7900.
-
(2009)
J Med Chem
, vol.52
, pp. 7897-7900
-
-
Volpini, R.1
Buccioni, M.2
Dal Ben, D.3
Lambertucci, C.4
Lammi, C.5
Marucci, G.6
Ramadori, A.T.7
Klotz, K.N.8
Cristalli, G.9
-
343
-
-
31544478810
-
Mechanisms of hypoxic tolerance in presymptomatic APP23 transgenic mice
-
von Arnim CA, Verstege E, Etrich SM, and Riepe MW (2006) Mechanisms of hypoxic tolerance in presymptomatic APP23 transgenic mice. Mech Ageing Dev 127:109–114.
-
(2006)
Mech Ageing Dev
, vol.127
, pp. 109-114
-
-
Von Arnim, C.A.1
Verstege, E.2
Etrich, S.M.3
Riepe, M.W.4
-
344
-
-
0033597008
-
Adenosine and cerebral ischemia: Therapeutic future or death of a brave concept?
-
von Lubitz DK (1999) Adenosine and cerebral ischemia: therapeutic future or death of a brave concept? Eur J Pharmacol 371:85–102.
-
(1999)
Eur J Pharmacol
, vol.371
, pp. 85-102
-
-
Von Lubitz, D.K.1
-
345
-
-
0028170345
-
Adenosine A3 receptor stimulation and cerebral ischemia
-
Von Lubitz DKJE, Lin RCS, Popik P, Carter MF, and Jacobson KA (1994) Adenosine A3 receptor stimulation and cerebral ischemia. Eur J Pharmacol 263:59–67.
-
(1994)
Eur J Pharmacol
, vol.263
, pp. 59-67
-
-
Von Lubitz, D.1
Lin, R.2
Popik, P.3
Carter, M.F.4
Jacobson, K.A.5
-
346
-
-
0034930857
-
Right thing at a wrong time? Adenosine A3 receptors and cerebroprotection in stroke
-
Von Lubitz DKJE, Simpson KL, and Lin RCS (2001) Right thing at a wrong time? Adenosine A3 receptors and cerebroprotection in stroke. Ann N Y Acad Sci 939:85–96.
-
(2001)
Ann N Y Acad Sci
, vol.939
, pp. 85-96
-
-
Von Lubitz, D.1
Simpson, K.L.2
Lin, R.3
-
347
-
-
37349054485
-
Preparation and first evaluation of [(18)F]FE@SUPPY: A new PET tracer for the adenosine A(3) receptor
-
Wadsak W, Mien LK, Shanab K, Ettlinger DE, Haeusler D, Sindelar K, Lanzenberger RR, Spreitzer H, Viernstein H, and Keppler BK, et al. (2008) Preparation and first evaluation of [(18)F]FE@SUPPY: a new PET tracer for the adenosine A(3) receptor. Nucl Med Biol 35:61–66.
-
(2008)
Nucl Med Biol
, vol.35
, pp. 61-66
-
-
Wadsak, W.1
Mien, L.K.2
Shanab, K.3
Ettlinger, D.E.4
Haeusler, D.5
Sindelar, K.6
Lanzenberger, R.R.7
Spreitzer, H.8
Viernstein, H.9
Keppler, B.K.10
-
348
-
-
37349025060
-
The A3 adenosine receptor agonist CP-532,903 [N6-(2,5-dichlorobenzyl)-39-aminoadenosine-59-N-methylcarboxamide] protects against myocardial ischemia/reperfusion injury via the sarcolemmal ATP-sensitive potassium channel
-
Wan TC, Ge ZD, Tampo A, Mio Y, Bienengraeber MW, Tracey WR, Gross GJ, Kwok WM, and Auchampach JA (2008) The A3 adenosine receptor agonist CP-532,903 [N6-(2,5-dichlorobenzyl)-39-aminoadenosine-59-N-methylcarboxamide] protects against myocardial ischemia/reperfusion injury via the sarcolemmal ATP-sensitive potassium channel. J Pharmacol Exp Ther 324:234–243.
-
(2008)
J Pharmacol Exp Ther
, vol.324
, pp. 234-243
-
-
Wan, T.C.1
Ge, Z.D.2
Tampo, A.3
Mio, Y.4
Bienengraeber, M.W.5
Tracey, W.R.6
Gross, G.J.7
Kwok, W.M.8
Auchampach, J.A.9
-
349
-
-
80055018439
-
Polyamidoamine (PAMAM) dendrimer conjugate specifically activates the A3 adenosine receptor to improve post-ischemic/reperfusion function in isolated mouse hearts
-
Wan TC, Tosh DK, Du L, Gizewski ET, Jacobson KA, and Auchampach JA (2011) Polyamidoamine (PAMAM) dendrimer conjugate specifically activates the A3 adenosine receptor to improve post-ischemic/reperfusion function in isolated mouse hearts. BMC Pharmacol 11:11.
-
(2011)
BMC Pharmacol
, vol.11
-
-
Wan, T.C.1
Tosh, D.K.2
Du, L.3
Gizewski, E.T.4
Jacobson, K.A.5
Auchampach, J.A.6
-
350
-
-
70749118702
-
Nucleoside-derived antagonists to A3 adenosine receptors lower mouse intraocular pressure and act across species
-
Wang Z, Do CW, Avila MY, Peterson-Yantorno K, Stone RA, Gao ZG, Joshi B, Besada P, Jeong LS, and Jacobson KA, et al. (2010) Nucleoside-derived antagonists to A3 adenosine receptors lower mouse intraocular pressure and act across species. Exp Eye Res 90:146–154.
-
(2010)
Exp Eye Res
, vol.90
, pp. 146-154
-
-
Wang, Z.1
Do, C.W.2
Avila, M.Y.3
Peterson-Yantorno, K.4
Stone, R.A.5
Gao, Z.G.6
Joshi, B.7
Besada, P.8
Jeong, L.S.9
Jacobson, K.A.10
-
351
-
-
0344826090
-
Extracellular ATP and adenosine induce cell apoptosis of human hepatoma Li-7A cells via the A3 adenosine receptor
-
Wen LT and Knowles AF (2003) Extracellular ATP and adenosine induce cell apoptosis of human hepatoma Li-7A cells via the A3 adenosine receptor. Br J Pharmacol 140:1009–1018.
-
(2003)
Br J Pharmacol
, vol.140
, pp. 1009-1018
-
-
Wen, L.T.1
Knowles, A.F.2
-
352
-
-
2542421699
-
Adenosine A3 receptor-induced CCL2 synthesis in cultured mouse astrocytes
-
Wittendorp MC, Boddeke HW, and Biber K (2004) Adenosine A3 receptor-induced CCL2 synthesis in cultured mouse astrocytes. Glia 46:410–418.
-
(2004)
Glia
, vol.46
, pp. 410-418
-
-
Wittendorp, M.C.1
Boddeke, H.W.2
Biber, K.3
-
353
-
-
0037063720
-
Decreased inflammatory pain due to reduced carrageenaninduced inflammation in mice lacking adenosine A3 receptors
-
Wu WP, Hao JX, Halldner-Henriksson L, Xu XJ, Jacobson MA, Wiesenfeld-Hallin Z, and Fredholm BB (2002) Decreased inflammatory pain due to reduced carrageenaninduced inflammation in mice lacking adenosine A3 receptors. Neuroscience 114: 523–527.
-
(2002)
Neuroscience
, vol.114
, pp. 523-527
-
-
Wu, W.P.1
Hao, J.X.2
Halldner-Henriksson, L.3
Xu, X.J.4
Jacobson, M.A.5
Wiesenfeld-Hallin, Z.6
Fredholm, B.B.7
-
355
-
-
0037132548
-
Activity of the A3 adenosine receptor gene promoter in transgenic mice: Characterization of previously unidentified sites of expression
-
Yaar R, Lamperti ED, Toselli PA, and Ravid K (2002) Activity of the A3 adenosine receptor gene promoter in transgenic mice: characterization of previously unidentified sites of expression. FEBS Lett 532:267–272.
-
(2002)
FEBS Lett
, vol.532
, pp. 267-272
-
-
Yaar, R.1
Lamperti, E.D.2
Toselli, P.A.3
Ravid, K.4
-
356
-
-
22744435457
-
The cross-species A3 adenosine-receptor antagonist MRS 1292 inhibits adenosine-triggered human nonpigmented ciliary epithelial cell fluid release and reduces mouse intraocular pressure
-
Yang H, Avila MY, Peterson-Yantorno K, Coca-Prados M, Stone RA, Jacobson KA, and Civan MM (2005) The cross-species A3 adenosine-receptor antagonist MRS 1292 inhibits adenosine-triggered human nonpigmented ciliary epithelial cell fluid release and reduces mouse intraocular pressure. Curr Eye Res 30:747–754.
-
(2005)
Curr Eye Res
, vol.30
, pp. 747-754
-
-
Yang, H.1
Avila, M.Y.2
Peterson-Yantorno, K.3
Coca-Prados, M.4
Stone, R.A.5
Jacobson, K.A.6
Civan, M.M.7
-
357
-
-
0031575663
-
Adenosine A3 receptor agonists protect HL-60 and U-937 cells from apoptosis induced by A3 antagonists
-
Yao Y, Sei Y, Abbracchio MP, Jiang JL, Kim YC, and Jacobson KA (1997) Adenosine A3 receptor agonists protect HL-60 and U-937 cells from apoptosis induced by A3 antagonists. Biochem Biophys Res Commun 232:317–322.
-
(1997)
Biochem Biophys Res Commun
, vol.232
, pp. 317-322
-
-
Yao, Y.1
Sei, Y.2
Abbracchio, M.P.3
Jiang, J.L.4
Kim, Y.C.5
Jacobson, K.A.6
-
358
-
-
27444435891
-
Antinociception of intrathecal adenosine receptor subtype agonists in rat formalin test
-
Yoon MH, Bae HB, and Choi JI (2005) Antinociception of intrathecal adenosine receptor subtype agonists in rat formalin test. Anesth Analg 101:1417–1421.
-
(2005)
Anesth Analg
, vol.101
, pp. 1417-1421
-
-
Yoon, M.H.1
Bae, H.B.2
Choi, J.I.3
-
359
-
-
3142754919
-
A3 adenosine receptor signaling contributes to airway inflammation and mucus production in adenosine deaminase-deficient mice
-
Young HW, Molina JG, Dimina D, Zhong H, Jacobson M, Chan LN, Chan TS, Lee JJ, and Blackburn MR (2004) A3 adenosine receptor signaling contributes to airway inflammation and mucus production in adenosine deaminase-deficient mice. J Immunol 173:1380–1389.
-
(2004)
J Immunol
, vol.173
, pp. 1380-1389
-
-
Young, H.W.1
Molina, J.G.2
Dimina, D.3
Zhong, H.4
Jacobson, M.5
Chan, L.N.6
Chan, T.S.7
Lee, J.J.8
Blackburn, M.R.9
-
360
-
-
80052147341
-
Differential roles of GSK-3b during myocardial ischemia and ischemia/reperfusion
-
Zhai P, Sciarretta S, Galeotti J, Volpe M, and Sadoshima J (2011) Differential roles of GSK-3b during myocardial ischemia and ischemia/reperfusion. Circ Res 109: 502–511.
-
(2011)
Circ Res
, vol.109
, pp. 502-511
-
-
Zhai, P.1
Sciarretta, S.2
Galeotti, J.3
Volpe, M.4
Sadoshima, J.5
-
361
-
-
33747375453
-
Identification of the A3 adenosine receptor in rat retinal ganglion cells
-
Zhang M, Budak MT, Lu W, Khurana TS, Zhang X, Laties AM, and Mitchell CH (2006a) Identification of the A3 adenosine receptor in rat retinal ganglion cells. Mol Vis 12:937–948.
-
(2006)
Mol Vis
, vol.12
, pp. 937-948
-
-
Zhang, M.1
Budak, M.T.2
Lu, W.3
Khurana, T.S.4
Zhang, X.5
Laties, A.M.6
Mitchell, C.H.7
-
362
-
-
73449129305
-
The A3 adenosine receptor attenuates the calcium rise triggered by NMDA receptors in retinal ganglion cells
-
Zhang M, Hu H, Zhang X, Lu W, Lim J, Eysteinsson T, Jacobson KA, Laties AM, and Mitchell CH (2010) The A3 adenosine receptor attenuates the calcium rise triggered by NMDA receptors in retinal ganglion cells. Neurochem Int 56:35–41.
-
(2010)
Neurochem Int
, vol.56
, pp. 35-41
-
-
Zhang, M.1
Hu, H.2
Zhang, X.3
Lu, W.4
Lim, J.5
Eysteinsson, T.6
Jacobson, K.A.7
Laties, A.M.8
Mitchell, C.H.9
-
363
-
-
38949130488
-
OARSI recommendations for the management of hip and knee osteoarthritis, Part II: OARSI evidence-based, expert consensus guidelines
-
Zhang W, Moskowitz RW, Nuki G, Abramson S, Altman RD, Arden N, Bierma- Zeinstra S, Brandt KD, Croft P, and Doherty M, et al. (2008) OARSI recommendations for the management of hip and knee osteoarthritis, Part II: OARSI evidence-based, expert consensus guidelines. Osteoarthritis Cartilage 16:137–162.
-
(2008)
Osteoarthritis Cartilage
, vol.16
, pp. 137-162
-
-
Zhang, W.1
Moskowitz, R.W.2
Nuki, G.3
Abramson, S.4
Altman, R.D.5
Arden, N.6
Bierma-Zeinstra, S.7
Brandt, K.D.8
Croft, P.9
Doherty, M.10
-
364
-
-
33746567885
-
Balance of purines may determine life or death of retinal ganglion cells as A3 adenosine receptors prevent loss following P2X7 receptor stimulation
-
Zhang X, Zhang M, Laties AM, and Mitchell CH (2006b) Balance of purines may determine life or death of retinal ganglion cells as A3 adenosine receptors prevent loss following P2X7 receptor stimulation. J Neurochem 98:566–575.
-
(2006)
J Neurochem
, vol.98
, pp. 566-575
-
-
Zhang, X.1
Zhang, M.2
Laties, A.M.3
Mitchell, C.H.4
-
365
-
-
0036516501
-
Late preconditioning elicited by activation of adenosine A(3) receptor in heart: Role of NF- kappa B, iNOS and mitochondrial K (ATP) channel
-
Zhao TC and Kukreja RC (2002) Late preconditioning elicited by activation of adenosine A(3) receptor in heart: role of NF- kappa B, iNOS and mitochondrial K (ATP) channel. J Mol Cell Cardiol 34:263–277.
-
(2002)
J Mol Cell Cardiol
, vol.34
, pp. 263-277
-
-
Zhao, T.C.1
Kukreja, R.C.2
-
366
-
-
0037662806
-
Protein kinase C-delta mediates adenosine A3 receptor-induced delayed cardioprotection in mouse
-
Zhao TC and Kukreja RC (2003) Protein kinase C-delta mediates adenosine A3 receptor-induced delayed cardioprotection in mouse. Am J Physiol Heart Circ Physiol 285:H434–H441.
-
(2003)
Am J Physiol Heart Circ Physiol
, vol.285
, pp. H434-H441
-
-
Zhao, T.C.1
Kukreja, R.C.2
-
367
-
-
36849005071
-
Protective roles of adenosine A1, A2A, and A3 receptors in skeletal muscle ischemia and reperfusion injury
-
Zheng J, Wang R, Zambraski E, Wu D, Jacobson KA, and Liang BT (2007) Protective roles of adenosine A1, A2A, and A3 receptors in skeletal muscle ischemia and reperfusion injury. Am J Physiol Heart Circ Physiol 293:H3685–H3691.
-
(2007)
Am J Physiol Heart Circ Physiol
, vol.293
, pp. H3685-H3691
-
-
Zheng, J.1
Wang, R.2
Zambraski, E.3
Wu, D.4
Jacobson, K.A.5
Liang, B.T.6
-
368
-
-
0038205888
-
Activation of murine lung mast cells by the adenosine A3 receptor
-
Zhong H, Shlykov SG, Molina JG, Sanborn BM, Jacobson MA, Tilley SL, and Blackburn MR (2003) Activation of murine lung mast cells by the adenosine A3 receptor. J Immunol 171:338–345.
-
(2003)
J Immunol
, vol.171
, pp. 338-345
-
-
Zhong, H.1
Shlykov, S.G.2
Molina, J.G.3
Sanborn, B.M.4
Jacobson, M.A.5
Tilley, S.L.6
Blackburn, M.R.7
-
369
-
-
77952163386
-
Stimulation of the adenosine A3 receptor reverses vascular hyporeactivity after hemorrhagic shock in rats
-
Zhou R, Chen F, Li Q, Hu DY, and Liu LM (2010) Stimulation of the adenosine A3 receptor reverses vascular hyporeactivity after hemorrhagic shock in rats. Acta Pharmacol Sin 31:413–420.
-
(2010)
Acta Pharmacol Sin
, vol.31
, pp. 413-420
-
-
Zhou, R.1
Chen, F.2
Li, Q.3
Hu, D.Y.4
Liu, L.M.5
-
370
-
-
0026732707
-
Molecular cloning and characterization of an adenosine receptor: The A3 adenosine receptor
-
Zhou QY, Li C, Olah ME, Johnson RA, Stiles GL, and Civelli O (1992) Molecular cloning and characterization of an adenosine receptor: the A3 adenosine receptor. Proc Natl Acad Sci USA 89:7432–7436.
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 7432-7436
-
-
Zhou, Q.Y.1
Li, C.2
Olah, M.E.3
Johnson, R.A.4
Stiles, G.L.5
Civelli, O.6
-
371
-
-
80052015796
-
Colocalization and regulated physical association of presynaptic serotonin transporters with A₃adenosine receptors
-
Zhu CB, Lindler KM, Campbell NG, Sutcliffe JS, Hewlett WA, and Blakely RD (2011) Colocalization and regulated physical association of presynaptic serotonin transporters with A₃ adenosine receptors. Mol Pharmacol 80:458–465.
-
(2011)
Mol Pharmacol
, vol.80
, pp. 458-465
-
-
Zhu, C.B.1
Lindler, K.M.2
Campbell, N.G.3
Sutcliffe, J.S.4
Hewlett, W.A.5
Blakely, R.D.6
-
372
-
-
34250778339
-
Rapid stimulation of presynaptic serotonin transport by A(3) adenosine receptors
-
Zhu CB, Steiner JA, Munn JL, Daws LC, Hewlett WA, and Blakely RD (2007) Rapid stimulation of presynaptic serotonin transport by A(3) adenosine receptors. J Pharmacol Exp Ther 322:332–340.
-
(2007)
J Pharmacol Exp Ther
, vol.322
, pp. 332-340
-
-
Zhu, C.B.1
Steiner, J.A.2
Munn, J.L.3
Daws, L.C.4
Hewlett, W.A.5
Blakely, R.D.6
-
373
-
-
0033766981
-
Extracellular metabolism of ATP and other nucleotides
-
Zimmermann H (2000) Extracellular metabolism of ATP and other nucleotides. Naunyn Schmiedebergs Arch Pharmacol 362:299–309.
-
(2000)
Naunyn Schmiedebergs Arch Pharmacol
, vol.362
, pp. 299-309
-
-
Zimmermann, H.1
|