Adenosine A3 receptors: Novel ligands and paradoxical effects

Trends in Pharmacological Sciences

Volumn 19, Issue 5, 1998, Pages 184-191

  Jacobson, Kenneth A ^a  

^a NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1,4 DIHYDROPYRIDINE; ADENOSINE A3 RECEPTOR; FLAVONOID; TRIAZOLOQUINAZOLINE DERIVATIVE; TUMOR NECROSIS FACTOR ALPHA; ADENOSINE RECEPTOR; CYTOKINE; LIGAND;

APOPTOSIS; ASTHMA; BINDING AFFINITY; BRAIN ISCHEMIA; CLINICAL FEATURE; HEART PROTECTION; LIGAND BINDING; PRIORITY JOURNAL; RECEPTOR BINDING; REVIEW; ANIMAL; BRAIN; CELL CULTURE; CHO CELL; CULTURE TECHNIQUE; DRUG ANTAGONISM; DRUG EFFECT; DRUG POTENTIATION; HAMSTER; HEART; HUMAN; METABOLISM; RAT; SECOND MESSENGER; STRUCTURE ACTIVITY RELATION;

ANIMALS; BRAIN; CHO CELLS; CRICETINAE; CULTURE TECHNIQUES; CYTOKINES; HEART; HUMANS; LIGANDS; RATS; RECEPTOR, ADENOSINE A3; RECEPTORS, PURINERGIC P1; SECOND MESSENGER SYSTEMS; STRUCTURE-ACTIVITY RELATIONSHIP; TUMOR CELLS, CULTURED;

EID: 0031593681     PISSN: 01656147     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-6147(98)01203-6     Document Type: Article

References (49)

1. Olah, M. E. and Stiles, G. L. (1995) Annu. Rev. Pharmacol. Toxicol. 35, 581-606
2. Linden, J. (1994) Trends Pharmacol. Sci. 15, 298-306
3. Jacobson, K. A. and Suzuki, F. (1997) Drug Dev. Res. 39, 289-300
4. Dunwiddie, T. V., Diao, L., Kim, H. O., Jiang, J-l. and Jacobson, K. A. (1997) J. Neurosci. 17, 607-614
5. Abbracchio, M. P. et al. (1997) Biochem. Biophys. Res. Commun. 241, 297-304
6. Olah, M. E., Gallo-Rodriguez, C., Jacobson, K. A. and Stiles, G. L. (1994) Mol. Pharmacol. 45, 978-982
7. Shearman, L. P. and Weaver, D. R. (1997) Brain Res. 745, 10-20
8. Dixon A. K., Gubitz, A. K., Sirinathsinghji, D. J., Richardson, P. J. and Freeman, T. C. (1996) Br. J. Pharmacol. 118, 1461-1468
9. Jacobson, K. A. et al. (1995) Drugs Future 20, 689-699
10. von Lubitz, D. K. J. E., Lin, R. C-S., Popik, P., Carter, M. F. and Jacobson, K. A. (1994) Eur. J. Pharmacol. 263, 59-67
11. Beaven, M. A., Ramkumar V. and Ali, H. (1994) Trends Pharmacol. Sci. 15, 13-14
12. Walker, B. A. et al. (1997) Am. J. Respir. Cell. Mol. Biol. 16, 531-737
13. Knight, D. A. et al. (1997) J. Leukocyte Biol. 62, 465-468
14. Liu, G. S. et al. (1994) Cardiovasc. Res. 28, 1057-1061
15. Strickler, J., Jacobson, K. A. and Liang, B. T. (1996) J. Clin. Invest. 98, 1773-1779
16. Stambaugh, K., Jacobson, K. A., Jiang, J-l. and Liang, B. T. (1997) Am. J. Physiol. 273, H501-H505
17. Tracey, W. R. et al. (1997) Cardiovasc. Res. 33, 410-415
18. Kohno, Y., Ji, X. d., Mawhorter, S. D., Koshiba, M. and Jacobson, K. A. (1996) Blood 88, 3569-3574
19. Salvatore, C. A., Jacobson, M. A., Taylor, H. E., Linden, J. and Johnson, R. G. (1993) Proc. Natl. Acad. Sci. U. S. A. 90, 10365-10369
20. Linden, J. et al. (1993) Mol. Pharmacol. 44, 524-532
21. Auchampach, J. A. et al. (1997) Mol. Pharmacol. 52, 846-860
22. Abbracchio, M. P. et al. (1995) Mol. Pharmacol. 48, 1038-1045
23. Ali, H. et al. (1996) J. Pharmacol. Exp. Ther. 276, 837-845
24. Kohno, Y., Sei, Y., Koshiba, M., Kim, H. O. and Jacobson, K. A. (1996) Biochem. Biophys. Res. Commun. 219, 904-910
25. Shin, Y., Daly, J. W. and Jacobson, K. A. (1996) Drug Dev. Res. 39, 36-46
26. Sei, Y., von Lubitz, D. K. J. E., Abbracchio, M. P., Ji, X. d. and Jacobson, K. A. (1997) Drug Dev. Res. 40, 267-273
27. Fleming K. M. and Mogul, D. J. (1997) Neuropharmacology 36, 353-362
28. Shneyvays, V., Jacobson, K. A. and Shainberg, A. (1997) J. Mol. Cell. Cardiol. 29, 11A.
29. Bouma, M. G. et al. (1997) J. Immunol. 158, 5400-5408
30. Sajjadi, F. G., Takabayashi, K., Foster, A. C., Domingo, R. C. and Firestein, G. S. (1996) J. Immunol. 156, 3435-3442
31. Jacobson, K. A. et al. (1997) Neuropharmacology 36, 1157-1165
32. Abbracchio, M. P. et al. (1997) Ann. New York Acad. Sci. 825, 11-22
33. Palmer, T. M., Gettys, T. W. and Stiles, G. L. (1995) J. Biol. Chem. 270, 16895-16902
34. Palmer, T. M., Benovic, J. L. and Stiles, G. L. (1996) J. Biol. Chem. 271, 15272-15278
35. Karton, Y. et al. (1996) J. Med. Chem. 39, 2293-2301
36. Jiang, J-l. et al. (1997) J. Med. Chem. 40, 2596-2608
37. Kim, Y-C., Ji, X. d. and Jacobson, K. A. (1996) J. Med. Chem. 39, 4142-4148
38. Jacobson, M., Chakravarty, P. K., Johnson, R. G. and Norton, R. (1996) Drug Dev. Res. 37, 131
39. Yao, Y., Sei, Y., Abbracchio, M. P., Kim, Y-C. and Jacobson, K. A. (1997) Biochem. Biophys. Res. Commun. 232, 317-322
40. von Lubitz, D. K. J. E., Lin, R. C-S. and Jacobson, K. A. (1997) Soc. Neurosci. Abstr. 23, 1924
41. Macek, T. A. and Conn, P. J. (1997) Soc. Neurosci. Abstr. 23, 1754
42. Meade, C. J., Mierau, J., Leon, I. and Ensinger, H. A. (1996) J. Pharmacol. Exp. Ther. 279, 1148-1156
43. el-Hashim, A., D'Agostino, B., Matera, M. G. and Page, C. (1996) Br. J. Pharmacol. 119, 1262-1268
44. Ali, S., Jacobson, K. A. and Mustafa, S. J. (1997) FASEB J. 11, A346
45. MacKenzie, W. M., Hoskin, D. W. and Blay, J. (1994) Cancer Res. 54, 3521-3526
46. Fozard, J. R., Pfannkuche, H. J. and Schuurman, H. J. (1996) Eur. J. Pharmacol. 298, 293-297
47. Shepherd, R. K., Linden, J. and Duling, B. R. (1996) Circ. Res. 78, 627-634
48. Auchampach, J. A. et al. (1997) Circ. Res. 80, 800-809
49. Liang, B. T. and Jacobson, K. A. Proc. Natl. Acad. Sci. U. S. A. (in press)