Adenosine modulates HIF-1α, VEGF, IL-8, and foam cell formation in a human model of hypoxic foam cells

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 30, Issue 1, 2010, Pages 90-97

  Gessi, Stefania ^a   Fogli, Eleonora ^a   Sacchetto, Valeria ^a   Merighi, Stefania ^a   Varani, Katia ^a   Preti, Delia ^b   Leung, Edward ^c   MacLennan, Stephen ^c   Borea, Pier Andrea ^a  

^a Interdisciplinary Center for the Study of Inflammation   (Italy)

^b UNIVERSITY OF FERRARA   (Italy)

^c King Pharmaceuticals   (United States)

Author keywords

A3 A2B antagonists; Adenosine receptors; Atherosclerosis; Foam cells; HIF 1

Indexed keywords

ADENOSINE; ADENOSINE A1 RECEPTOR; ADENOSINE A2A RECEPTOR; ADENOSINE A2B RECEPTOR; ADENOSINE A3 RECEPTOR; ADENOSINE RECEPTOR; HYPOXIA INDUCIBLE FACTOR 1ALPHA; INTERLEUKIN 8; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN KINASE B; VASCULOTROPIN;

ANGIOGENESIS; ARTICLE; ATHEROGENESIS; ATHEROSCLEROTIC PLAQUE; CELL HYPOXIA; CONTROLLED STUDY; ENZYME PHOSPHORYLATION; FOAM CELL; HUMAN; HUMAN CELL; HYPOXIC CELL; PRIORITY JOURNAL;

ADENOSINE; ANOXIA; ATHEROSCLEROSIS; AZO COMPOUNDS; COLORING AGENTS; FOAM CELLS; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; INTERLEUKIN-8; LIPOPROTEINS, LDL; MACROPHAGES; MAP KINASE SIGNALING SYSTEM; PROTO-ONCOGENE PROTEINS C-AKT; RECEPTOR, ADENOSINE A1; RECEPTOR, ADENOSINE A2A; RECEPTOR, ADENOSINE A2B; RNA, MESSENGER; U937 CELLS; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 73849123855     PISSN: 10795642     EISSN: None     Source Type: Journal    
DOI: 10.1161/ATVBAHA.109.194902     Document Type: Article

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