Polyamidoamine (PAMAM) dendrimer conjugates of "clickable" agonists of the A3 adenosine receptor and coactivation of the P2Y14 receptor by a tethered nucleotide

Bioconjugate Chemistry

Volumn 21, Issue 2, 2010, Pages 372-384

  Tosh, Dilip K ^a   Yoo, Lena S ^a   Chinn, Moshe ^a   Hong, Kunlun ^b   Kilbey II, S Michael ^b   Barrett, Matthew O ^c   Fricks, Ingrid P ^c   Harden, T Kendall ^c   Gao, Zhan Guo ^a   Jacobson, Kenneth A ^a  

^a NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^b OAK RIDGE NATIONAL LABORATORY   (United States)

^c UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 [4 (2 CARBOXYETHYL)PHENETHYLAMINO]ADENOSINE 5' (N ETHYLCARBOXAMIDE); 6 HEPTYNOIC ACID; 6 N (3 IODOBENZYL)ADENOSINE 5' N METHYLCARBOXAMIDE; 6N (4 AMINO 3 IODOBENZYL)ADENOSINE 5' N METHYLURONAMIDE; ADENINE; ADENOSINE A1 RECEPTOR; ADENOSINE A2A RECEPTOR; ADENOSINE A3 RECEPTOR; ADENOSINE RECEPTOR STIMULATING AGENT; ADENYLATE CYCLASE; ALKYNE; AMIDE; ANTIINFLAMMATORY AGENT; AZIDE; CARBOXYLIC ACID DERIVATIVE; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; DENDRIMER; LIGAND; NUCLEOSIDE; NUCLEOTIDE; POLYAMIDOAMINE; POLYAMIDOAMINE DENDRIMER CONJUGATE; PURINERGIC P2Y RECEPTOR; PURINERGIC P2Y14 RECEPTOR; RADIOLIGAND; TRIAZOLE DERIVATIVE; UNCLASSIFIED DRUG; URIDINE DIPHOSPHATE GLUCOSE; URIDINE DIPHOSPHATE GLUCURONIC ACID; WATER;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; CELL CULTURE; DRUG CONJUGATION; DRUG DESIGN; DRUG RECEPTOR BINDING; DRUG SELECTIVITY; DRUG SYNTHESIS; HUMAN; HUMAN CELL; NONHUMAN; STRUCTURE ACTIVITY RELATION;

EID: 77049109479     PISSN: 10431802     EISSN: 15204812     Source Type: Journal    
DOI: 10.1021/bc900473v     Document Type: Article

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